Cardiovascular Models
Cardiovascular disease is a leading cause of death in the UK and its social and economic cost is increasing constantly due to our ageing society. Queen Mary University of London (QMUL) has a longstanding commitment to world-leading research to better understand and treat heart disease. Activities include the development of innovative cardiovascular devices at the Centre for Cardiovascular Medicine and Device Innovation (CVDHub), as well as basic and translational cardiovascular research at the William Harvey Research Institute (WHRI), or molecular and computational cardiovascular engineering at the School of Engineering and Materials Science
The Centre for Predictive In Vitro Models (CPM) ties in directly with these activities by focusing on advanced three dimensional vascular networks and cardiac tissues for improving understanding of disease mechanisms and development of novel treatments. Currently ongoing state-of-the art projects include bioprinted vessels-on-a-chip (Gautrot Lab), vascular disease modelling based on induced pluripotent stem cells and models for studying vascular endothelial mechanosensing (Xiao Lab, Wang Lab, Krams Lab), bio-nanoarrays to study cardiomyocyte and vascular smooth muscle cell receptor-ligand interactions (Palma Lab, Iskratsch Lab), force sensing nanopillar arrays to measure cardiomyocyte contraction dynamics, or engineered heart tissues for investigating the effects of cardiac disease causing mutations or cardiotoxicity of drugs (Iskratsch Lab, Lin Lab, Tinker Lab).
People
- Prof Thomas Iskratsch
Theme Lead for Cardiovascular Models
Professor of Cardiovascular Mechanobiology and Bioengineering, Queen Mary University of London - Dr Vahitha Abdul Salam
Lecturer, Queen Mary University of London - Prof Amrita Ahluwalia
Dean For Research Faculty of Medicine and Dentistry, QMUL - Prof Jesmond Dalli
Professor in Molecular Pharmacology, Barts and The London School of Medicine and Dentistry - Dr Neil Dufton
Lecturer in Inflammatory Sciences, Faculty of Medicine and Dentistry, Queen Mary University of London - Prof Julien Gautrot
Professor of Biomaterials and Biointerfaces, Queen Mary University of London - Prof Steve Greenwald
Professor of Cardiovascular Mechanics, Faculty of Medicine and Dentistry, Queen Mary University of London - Prof Adrian Hobbs
Professor of Cardiovascular Pharmacology, Faculty of Medicine and Dentistry, Queen Mary University of London - Prof David Kelsell
Professor of Human Molecular Genetics, Faculty of Medicine and Dentistry, Queen Mary University of London - Prof Martin Knight
Professor of Mechanobiology, Dean for Research, Queen Mary University of London - Prof Rob Krams
Professor of Molecular Bioengineering, Queen Mary University of London - Prof David Lee
Professor of Cell & Tissue Engineering, Queen Mary University of London - Dr Yung-Yao Lin
Senior Lecturer, Faculty of Medicine and Dentistry, Queen Mary University of London - Dr Pradeepa Madapura
Senior Lecturer, Faculty of Medicine and Dentistry - Dr Simon McArthur
Senior Lecturer in Neuroscience and Pharmacology, Faculty of Medicine and Dentistry, Queen Mary University of London - Prof Lou Metherell
Professor of Endocrine Genetics, Faculty of Medicine and Dentistry, Queen Mary University of London - Dr Tom Nightingale
Senior Lecturer, Faculty of Medicine and Dentistry, Queen Mary University of London - Prof Mauro Perretti
Professor of Immunopharmacology, Queen Mary University of London - Dr Caroline Roney
Lecturer in Computational Medicine, Queen Mary University of London - Prof Hazel Screen
Professor of Biomedical Engineering, Queen Mary University of London - Prof Greg Slabaugh
Director of the Digital Environment Research Institute, Queen Mary University of London - Dr Manikandan Subramanian
Senior Lecturer, William Harvey Research Institute - Prof Yi Sui
Professor of Fluid Mechanics, Queen Mary University of London - Prof Andrew Tinker
, Faculty of Medicine and Dentistry, Queen Mary University of London - Prof Zion Tse
Academy of Medical Sciences Professor in Bioengineering, Queen Mary University of London - Prof Wen Wang
Vice-Principal and Executive Dean, Queen Mary University of London - Prof Qingzhong Xiao
Professor of Stem Cell and Cardiovascular Disease, Faculty of Medicine and Dentistry, Queen Mary University of London