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Bioengineering and Mechanobiology

Work from Prof Gautrou showing cells proliferating on nanosheets self-assembled at liquid-liquid interfaces
Work from Prof Gautrot showing cells proliferating on nanosheets self-assembled at liquid-liquid interfaces

Researchers in the Centre for Predictive in vitro Models are actively engaged in Bioengineering research that underpins the development of new in vitro models and organ-on-a-chip technology. This includes aspects of biomaterials, manufacture, 3D printing and microfluidics. This area of work links closely with the Queen Mary Institute of Bioengineering and the Bioengineering Division within the School of Engineering and Materials Science.

In addition, Queen Mary University of London has a critical mass of researchers in the area of Mechanobiology, exploring the effects of mechanical stimuli on cell function.  This requires understanding of the physiological and pathological biomechanics and the development of bioengineering technology to apply these stimuli within the context of predictive in vitro models. In addition mechanical stimuli in the form of physical or topographical cues may be used within in vitro models to drive cell differentiation and the production of physiologically relevant extracellaular matrix.