• Different platforms for pre-clinical translational models as available at the CPM
  • Members of the CPM at MPS conference
  • Micro-patterned <em>in vitro</em> model of keratinocyte colonies
  • Ciliated cells inside an airway organ-chip from Emulate

A World-Leading Centre for Predictive in vitro Model Research, Training and Translation

Our vision is to work with key stakeholders to develop and translate innovative in vitro models for highest quality discovery science and to accelerate delivery of safe and effective medicines for the benefit of wider society.

Research with the Centre incorporates a wide range of model systems including 2D and 3D cell culture models, organoids, microphysiological systems, organ-on-a-chip technology, Non Animal Methods (NAMs), and other pre-clinical translational models.

With approximately 100 academic staff across the Faculty of Science and Engineering and the Faculty of Medicine and Dentistry, Queen Mary's Centre for Predictive in vitro Models is leading development and use of these complex in vitro models in partnership an extensive list of partners and industry affiliates.

Queen Mary provide leadership in this field hosting the annual UK symposium and engaging with Government, policy makers, funders, industry and other stake holders to support development and adoption of this transformative technology.

Events

News

Recent Publications

  • Human coronary artery organ‐chip with circulating immune cells recapitulates anti‐inflammatory effect of pulsatile wall strain
    Hou Y, Ziakas G, Hopkins T, Wang W, Screen HRC, Knight MM
    Interdisciplinary Medicine, Wiley 
    10-03-2026
  • Neuromodulation of a peripheral nerve using fully polymeric cuff electrodes: understanding predictability of selective stimulation
    Bailey ZK, Nairac Z, Cuttaz EA, M’Rad IB, Chapman CAR, Rapeaux A, Goding JA, Roche AD et al.
    Journal of Neural Engineering, Iop Publishing vol. 23 (1) 
    01-02-2026
  • DOP078 Development of a bioengineered 3D model of gut barrier defence against Candida albicans invasion and inflammasome activation in Crohn’s Disease
    Carlson S, Mathew L, Pardieu C, Hindle S, Khan M, Blowes L, Munro C, Connelly J et al.
    Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 20 (Supplement_1) 
    01-01-2026

View more publications »

Recent Grants

  • Developing a rapid diagnostic to track the spread of an emerging fungal pathogen in East London
    Kieran Bates
    £73,168 Barts and the London Charity
    01-04-2026 - 30-09-2027
  • FROGMICRO Host control and symbiont counter-adaptation in the microbiome ERC STG 2025 Bates
    Kieran Bates
    £1,181,557 EU Commission - Horizon Europe
    01-02-2026 - 31-01-2031
  • COaCT - Development of a vascularised muscle-tendon inflammation-on-a-chip model
    Hazel Screen and Martin Knight
    £166,623 UCB Pharma SPRL 
    Grant Summary

    01-10-2025 - 30-09-2029

View more grants »