A World-Leading Centre for Predictive in vitro Model Research, Training and Translation
The Queen Mary Centre for Predictive in vitro Models (CPM) provides a beacon of multidisciplinary research, training, and translation focusing on the development and use of predictive in vitro models. This incorporates a wide range of model systems including 2D and 3D cell culture models, organoids, microphysiological systems, organ-on-a-chip technology, Non Animal Methods (NAMs), and other types of in vitro model.
With approximately 100 academic staff across the Faculty of Science and Engineering and the Faculty of Medicine and Dentistry, Queen Mary's Centre for Predictive in vitro Models is leading development and use of these complex in vitro models in partnership an extensive list of partners and industry affiliates.
Queen Mary provide leadership in this field hosting the annual UK symposium and engaging with Government, policy makers, funders, industry and other stake holders to support development and adoption of this transformative technology.
Events
 Thu 1 May 202509:30 - 17:00 | NC3Rs NAMs Network symposium |
| Mon 9 - Fri 13 Jun 2025 | Microphysiological Systems (MPS) World Summit 2025 |
| Mon 16 - Tue 17 Jun 2025 | 3rd Workshop on the European Commission roadmap towards phasing out animal testing for chemical safety assessments |
| Wed 18 - Fri 20 Jun 2025 | Tissue & Cell Engineering Society Conference 2025 |
Recent Publications
- Haemodynamic measurements during hip hemiarthroplasty surgery for hip fracture
Fernandez MA, Henshaw F, Carlos WJ, Kelly A, Griffin XL and Costa ML
The Bone & Joint Journal, British Editorial Society of Bone & Joint Surgery vol. 107-B (1), 103-107.
01-01-2025 - Role of Myofibroblasts in the Repair of Iatrogenic Preterm Membranes Subjected to Mechanical Stimulation
Costa E, Thrasivoulou C, Becker DL, Deprest J, David AL and Chowdhury TT
Prenatal Diagnosis, Wiley
04-12-2024 - Cerebrovascular damage caused by the gut microbe/host co-metabolite p-cresol sulfate is prevented by blockade of the EGF receptor
Shah SN, Knausenberger TB-A, Pontifex MG, Connell E, Le Gall G, Hardy TAJ, Randall DW, McCafferty K, Yaqoob MM, Solito E, Müller M, Stachulski AV, Glen RC, Vauzour D, Hoyles L and McArthur S
Gut Microbes, Taylor & Francis vol. 16 (1), 2431651-2431651.
24-11-2024
Recent Grants
- Investigating perfused inflammatory and immune responses in 3D barrier-immune models for atopic dermatitis
John Connelly
£196,508
01-02-2025 - 31-01-2026 - Investigating the roles of endogenous retro viruses as regulators of gene expression in the endometrial epithelium
Miguel Branco
£731,019 BBSRC Biotechnology and Biological Sciences Research Council
01-02-2025 - 31-01-2028 - Open Trauma Assessment Study
Christopher Bretherton, Xavier Griffin and Jamila Kassam
£2,740 AO Foundation
01-11-2024 - 31-10-2026