Queen Mary University of LondonQueen Mary University of London
  • Micro-patterned <em>in vitro</em> model of keratinocyte colonies
  • Ciliated cells inside Emulate's lung-chip
  • Cells growing in oil droplet model
  • Villi-like structures inside Emulate's intestine-chip
  • Microvilli inside Emulate's intestine-chip
  • Ciliated cells inside Emulate’s lung-chip

Welcome to the Centre for Predictive in vitro Models

The Centre for Predictive in vitro Models (CPM) represents multidisciplinary research focusing on the development and use of predictive in vitro models. This incorporates a wide range of model systems including 2D and 3D cell culture models, organoids, microphysiological systems and organ-on-a-chip technology. 

Our vision is to facilitate the implementation of innovative in vitro models in order to deliver highest quality discovery science and transformative healthcare solutions.

Researchers across Queen Mary are using these in vitro models to examine fundamental hypotheses around health and disease and to test new therapeutics strategies. This is supported by bioengineers who are developing these complex in vitro models and the underpinning technology including aspects of microfluidics, biomaterials, mechanobiology, computational modelling, micromanufacture and 3D printing. 

Our research is closely linked to the regulatory authorities, pharmaceuticals industry and companies developing the technology platforms. In particular Queen Mary has a major new strategic collaboration with the internationally leading organs-on-chips company, Emulate. Together we have established the Queen Mary-Emulate Organs-on-chips Centre which provides unique access for academia and industry to Emulate's organ-on-a-chip platforms with full technical and scientific support. 

Queen Mary also runs the UK Organ-on-a-Chip Technologies Network funded by the EPSRC, MRC and BBSRC via the Technologies Touching Life Scheme. This flourishing network consists of over 500 members and approximately 50 industrial partners and other stake holders.