• Ciliated cells inside Emulate's lung-chip
  • Micro-patterned <em>in vitro</em> model of keratinocyte colonies
  • Cells growing in oil droplet model
  • Villi-like structures inside Emulate's intestine-chip
  • Microvilli inside Emulate's intestine-chip
  • Ciliated cells inside Emulate’s lung-chip

A World-Leading Centre for Predictive in vitro Model Research, Training and Translation

The Queen Mary, Centre for Predictive in vitro Models (CPM) provides a beacon of multidisciplinary research, training, and translation focusing on the development and use of predictive in vitro models. This incorporates a wide range of model systems including 2D and 3D cell culture models, organoids, microphysiological systems, organ-on-a-chip technology, New Approach Methodologies (NAMs), Non Animal Technologies (NATs) and other types of in vitro model.

Our vision is to facilitate the implementation of innovative in vitro models for highest quality discovery science and to accelerate delivery of safe and effective therapeutics for the benefit of wider society.

With approximately 70 academic staff across the Faculty of Science and Engineering and the Faculty of Medicine and Dentistry, Queen Mary's Centre for Predictive in vitro Models is leading development and use of these complex in vitro models in partnership the regulatory authorities, pharmaceuticals and healthcare industry, companies developing the technology platforms, and other stake holders.

Queen Mary led the UK Organ-on-a-Chip Technologies Network funded by UKRI (2018-2022) with over 1,000 members from 60+ universities and multiple stake holder partners, successfully establishing the organ-chip community in the UK. Queen Mary continues to provide leadership in this field hosting the annual UK symposium and engaging with Government, policy makers, funders, industry and other stake holders to support development and adoption of this transformative technology.