Research Publications
The following journal papers published by the members of the CPM, specifically relate to the development and/or use of predictive in vitro models.
2024
Di Cio S, Marhuenda E, Haddrick M and Gautrot JE (2024). Vascularised cardiac spheroids-on-a-chip for testing the toxicity of therapeutics. Springer Nature Scientific Reports vol. 14, (1) 10.1038/s41598-024-53678-w
Scemama A, Lunetto S, Tailor A, Di Cio S, Dibble M, Gautrot J and Biddle A (2024). Development of an in vitro microfluidic model to study the role of microenvironmental cells in oral cancer metastasis. Faculty of 1000 F1000research vol. 12, 10.12688/f1000research.131810.2
2023
Verbruggen SW, Nolan J, Duffy MP, Pearce OMT, Jacobs CR and Knight MM (2023). A Novel Primary Cilium‐Mediated Mechanism Through which Osteocytes Regulate Metastatic Behavior of Both Breast and Prostate Cancer Cells. Wiley Advanced Science vol. 11, (2) 10.1002/advs.202305842
Thompson CL, Hopkins T, Bevan C, Screen HRC, Wright KT and Knight MM (2023). Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment. Iop Publishing Biomedical Materials vol. 18, (6) 10.1088/1748-605x/acf976
Rulten SL, Grose RP, Gatz SA, Jones JL and Cameron AJM (2023). The Future of Precision Oncology. Mdpi International Journal of Molecular Sciences vol. 24, (16) 10.3390/ijms241612613
Chen S, Cheng Y, Zhao Z, Zhang K, Hao T, Sui Y, Wang W, Zhao J and Li Y (2023). Core–Shell-Structured Electrorheological Fluid with a Polarizability-Tunable Nanocarbon Shell for Enhanced Stimuli-Responsive Activity. American Chemical Society (Acs) Acs Applied Materials & Interfaces vol. 15, (29) 35741-35749. 10.1021/acsami.3c07133
Gibson SV, Madzharova E, Tan AC, Allen MD, Keller UAD, Jones JL, Carter EP and Grose RP (2023). ADAMTS3 restricts cancer invasion in models of early breast cancer progression through enhanced fibronectin degradation. Elsevier Matrix Biology vol. 121, 74-89. 10.1016/j.matbio.2023.06.005
Neri-Cruz CE, Teixeira FME and Gautrot JE (2023). A guide to functionalisation and bioconjugation strategies to surface-initiated polymer brushes. Royal Society of Chemistry Chemical Communications vol. 59, (49) 7534-7558. 10.1039/d3cc01082a
Lu RX, Guo ZY, Yu P and Sui Y (2023). Transient deformation of a viscoelastic capsule in a cross-slot microchannel: effects of inertia and membrane viscosity. Cambridge University Press (Cup) Journal of Fluid Mechanics vol. 962, 10.1017/jfm.2023.298
Scemama A, Tailor A, Di Cio S, Dibble M, Gautrot J and Biddle A (2023). Development of an in vitro microfluidic model to study the role of microenvironmental cells in oral cancer metastasis. Taylor and Francis F1000research vol. 12, 439-439. 10.12688/f1000research.131810.1
Cervantes-Salguero K, Gutiérrez Fosado YA, Megone W, Gautrot JE and Palma M (2023). Programmed Self-Assembly of DNA Nanosheets with Discrete Single-Molecule Thickness and Interfacial Mechanics: Design, Simulation, and Characterization. Mdpi Molecules vol. 28, (9) 10.3390/molecules28093686
Dibble M, Di Cio’ S, Luo P, Balkwill F and Gautrot JE (2023). The impact of pericytes on the stability of microvascular networks in response to nanoparticles. Springer Nature Scientific Reports vol. 13, (1) 10.1038/s41598-023-31352-x
Joy JD, Malacrida B, Laforêts F, Kotantaki P, Maniati E, Hopkins S, Garrobo-Calleja I, Gautrot J and Balkwill F (2023). Abstract 4576: 3D in vitro models uncover malignant cell intrinsic and extrinsic mechanisms of CAR-T cell resistance in high grade serous ovarian cancer. American Association For Cancer Research (Aacr) Cancer Research vol. 83, (7_Supplement) 4576-4576. 10.1158/1538-7445.am2023-4576
Clayton NS, Carter EP, Fearon AE, Heward JA, Fernández LR, Boughetane L, Wilkes EH, Cutillas PR and Grose RP (2023). HDAC Inhibition Restores Response to HER2-Targeted Therapy in Breast Cancer via PHLDA1 Induction. Mdpi International Journal of Molecular Sciences vol. 24, (7) 10.3390/ijms24076228
Guo Z, Lin T, Jing D, Wang W and Sui Y (2023). A method for real-time mechanical characterisation of microcapsules. Springer Nature Biomechanics and Modeling in Mechanobiology vol. 22, (4) 1209-1220. 10.1007/s10237-023-01712-7
Bort ET, Joseph MD, Wang Q, Carter EP, Roth NJ, Gibson J, Samadi A, Kocher HM, Simoncelli S, McCormick PJ and Grose RP (2023). Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion. Elife Elife vol. 12, 10.7554/elife.86971
Peng L, Nadal C and Gautrot JE (2023). Growth of mesenchymal stem cells at the surface of silicone, mineral and plant-based oils. Iop Publishing Biomedical Materials vol. 18, (3) 10.1088/1748-605x/acbdda
Harley P, Paredes-Redondo A, Grenci G, Viasnoff V, Lin Y-Y and Lieberam I (2023). 3D Compartmentalised Human Pluripotent Stem Cell–derived Neuromuscular Co-cultures. Bio-Protocol vol. 13, (5) e4624-e4624. 10.21769/bioprotoc.4624
Gibson SV, Tomas Bort E, Rodríguez-Fernández L, Allen MD, Gomm JJ, Goulding I, auf dem Keller U, Agnoletto A, Brisken C, Peck B, Cameron AJ, Marshall JF, Jones JL, Carter EP and Grose RP (2023). TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression. Springer Nature Npj Breast Cancer vol. 9, (1) 10.1038/s41523-023-00513-6
Krishna Kumar R and Foster KR (2023). 3D printing of microbial communities: A new platform for understanding and engineering microbiomes. Microbial Biotechnology vol. 16, (3) 489-493. 10.1111/1751-7915.14168
Wang Z, Lu R, Wang W, Tian FB, Feng JJ and Sui Y (2023). A computational model for the transit of a cancer cell through a constricted microchannel. Springer Nature Biomechanics and Modeling in Mechanobiology vol. 22, (4) 1129-1143. 10.1007/s10237-023-01705-6
Peng L, Matellan C, Bosch‐Fortea M, Gonzalez‐Molina J, Frigerio M, Salentinig S, del Rio Hernandez A and Gautrot JE (2023). Mesenchymal Stem Cells Sense the Toughness of Nanomaterials and Interfaces. Wiley Advanced Healthcare Materials vol. 12, (13) 10.1002/adhm.202203297
Gibson SV, Roozitalab RM, Allen MD, Jones JL, Carter EP and Grose RP (2023). Everybody needs good neighbours: the progressive DCIS microenvironment. Elsevier Trends in Cancer vol. 9, (4) 326-338. 10.1016/j.trecan.2023.01.002
Hayat A, Carter EP, King HW, Ors A, Doe A, Teijeiro SA, Charrot S, Godinho S, Cutillas P, Mohammed H, Grose RP and Ficz G (2023). Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening. The Company of Biologists Disease Models & Mechanisms vol. 16, (2) 10.1242/dmm.049894
Nguyen KDQ, Dejean S, Nottelet B and Gautrot JE (2023). Mechanical Evaluation of Hydrogel–Elastomer Interfaces Generated through Thiol–Ene Coupling. American Chemical Society (Acs) Acs Applied Polymer Materials vol. 5, (2) 1364-1373. 10.1021/acsapm.2c01878
Chrysanthou A, Bosch-Fortea M and Gautrot JE (2023). Co-Surfactant-Free Bioactive Protein Nanosheets for the Stabilization of Bioemulsions Enabling Adherent Cell Expansion. American Chemical Society (Acs) Biomacromolecules vol. 24, (10) 4465-4477. 10.1021/acs.biomac.2c01289
Nolan J, Pearce OMT, Screen HRC, Knight MM and Verbruggen SW (2023). Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK. Mdpi Cancers vol. 15, (3) 10.3390/cancers15030635
Chrysanthou A, Kanso H, Zhong W, Shang L and Gautrot JE (2023). Supercharged Protein Nanosheets for Cell Expansion on Bioemulsions. American Chemical Society (Acs) Acs Applied Materials & Interfaces vol. 15, (2) 2760-2770. 10.1021/acsami.2c20188
Stachulski AV, Knausenberger TB-A, Shah SN, Hoyles L and McArthur S (2023). A host-gut microbial amino acid co-metabolite, p-cresol glucuronide, promotes blood-brain barrier integrity in vivo. Tissue Barriers vol. 11, (1) 10.1080/21688370.2022.2073175
Ri J, Pang N, Bai S, Xu J, Xu L, Ri S, Yao Y and Greenwald SE (2023). Three-dimensional numerical analysis of wall stress induced by asymmetric oscillation of microbubble trains inside micro-vessels. Aip Publishing Physics of Fluids vol. 35, (1) 10.1063/5.0134922
Azhar Z, Grose RP, Raza A and Raza Z (2023). In silico targeting of colony-stimulating factor-1 receptor: delineating immunotherapy in cancer. Open Exploration Publishing Exploration of Targeted Anti-Tumor Therapy vol. 4, (4) 727-742. 10.37349/etat.2023.00164
2022
Iskratsch T, Hawkes W, Marhuenda E, Reynolds P, O'Neill C, PANDEY P, Wilson D, FREELEY M, HUANG D, Junquiang H, Gondarenko S, Hone J, Gadegaard N and Palma M (2022). Regulation of Cardiomyocyte Adhesion and
Mechanosignalling Through Distinct Nanoscale Behaviour of
Integrin Ligands Mimicking Healthy or Fibrotic ECM. The Royal Society Philosophical Transactions of The Royal Society B: Biological Sciences 10.1098/rstb.2022.0021
Dembitz V, Lawson H, Philippe C, Burt RJ, James S, Magee ASM, Woodley K, Durko J, Campos J, Austin MJ, Rio-Machin A, Izquierdo PC, Bewicke-Copley F, Blanco GR, Patel B, Hazlehurst L, Peck B, Finch A, Cutillas P, Fitzgibbon J, Yuneva M, Rouault-Pierre K, Copland J, Kranc K and Gallipoli P (2022). Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia. American Society of Hematology Blood vol. 140, (Supplement 1) 3058-3060. 10.1182/blood-2022-166811
Meng H, Thompson CL, Coveney CR, Wann AK and Knight MM (2022). Techniques for Visualization and Quantification of Primary Cilia in Chondrocytes. Cartilage Tissue Engineering Springer Nature 10.1007/978-1-0716-2839-3_12
Coetzee AS, Carter EP, Rodríguez-Fernández L, Heward J, Wang Q, Karim SA, Boughetane L, Milton C, Uyulur F, Morton JP, Kocher HM and Grose RP (2022). Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1. Springer Nature Oncogene vol. 42, (7) 491-500. 10.1038/s41388-022-02513-5
Morera C, Kim J, Paredes-Redondo A, Nobles M, Rybin D, Moccia R, Kowala A, Meng J, Garren S, Liu P, Morgan JE, Muntoni F, Christoforou N, Owens J, Tinker A and Lin Y-Y (2022). CRISPR-mediated correction of skeletal muscle Ca2+ handling in a novel DMD patient-derived pluripotent stem cell model. Neuromuscular Disorders 10.1016/j.nmd.2022.10.007
Gautrot JE, Chang L, Alexis C, Gutfreund P and Zarbakhsh A (2022). The Architecture of Oligonucleotide-Polycationic Brush Complexes – A Neutron Reflectometry Study. Wiley Advanced Materials Interfaces 10.1002/admi.202201344
Ombrato L (2022). In vivo labelling system to study cell neighbourhoods. Springer Nature Nature Reviews Cancer vol. 22, (12) 661-661. 10.1038/s41568-022-00521-x
Hayward M-K, Allen MD, Gomm JJ, Goulding I, Thompson CL, Knight MM, Marshall JF and Jones JL (2022). Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion. Springer Nature Npj Breast Cancer vol. 8, (1) 10.1038/s41523-022-00464-4
Heywood HK, Gardner L, Knight MM and Lee DA (2022). Oscillations of the circadian clock protein, BMAL-1, align to daily cycles of mechanical stimuli: a novel means to integrate biological time within predictive in vitro model systems. Springer Nature In Vitro Models 1-8. 10.1007/s44164-022-00032-x
Cervantes-Salguero K, Freeley M, Gwyther REA, Jones DD, Chávez JL and Palma M (2022). Single molecule DNA origami nanoarrays with controlled protein orientation. Aip Publishing Biophysics Reviews vol. 3, (3) 10.1063/5.0099294
Sun C, Dong Y, Wei J, Cai M, Liang D, Fu Y, Zhou Y, Sui Y, Wu F, Mikhaylov R, Wang H, Fan F, Xie Z, Stringer M, Yang Z, Wu Z, Tian L and Yang X (2022). Acoustically accelerated neural differentiation of human embryonic stem cells. Elsevier Acta Biomaterialia vol. 151, 333-345. 10.1016/j.actbio.2022.07.041
Jones CFE, Di Cio S, Connelly JT and Gautrot JE (2022). Design of an Integrated Microvascularized Human Skin-on-a-Chip Tissue Equivalent Model. Frontiers Media Frontiers in Bioengineering and Biotechnology vol. 10, 10.3389/fbioe.2022.915702
Whiteford J, Arokiasamy S, Thompson C, Alazawi W and Dufton N (2022). FRI198 Investigating the function of Endothelial-To-Mesenchymal transition during liver fibrogenesis using a Liver-On-A-Chip platform. Elsevier Journal of Hepatology vol. 77, 10.1016/s0168-8278(22)01308-3
Sarmin AM, Moussaid NE, Suntornnond R, Tyler EJ, Kim Y-H, Di Cio S, Megone WV, Pearce O, Gautrot JE, Dawson J and Connelly JT (2022). Multi-Scale Analysis of the Composition, Structure, and Function of Decellularized Extracellular Matrix for Human Skin and Wound Healing Models. Mdpi Biomolecules vol. 12, (6) 10.3390/biom12060837
Lin T, Wang Z, Lu RX, Wang W and Sui Y (2022). Characterising Mechanical Properties of Flowing Microcapsules Using a Deep Convolutional Neural Network. Global Science Press Advances in Applied Mathematics and Mechanics vol. 14, (1) 79-100. 10.4208/aamm.oa-2020-0357
Rivellese F, Surace AEA, Goldmann K, Sciacca E, Çubuk C, Giorli G, John CR, Nerviani A, Fossati-Jimack L, Thorborn G, Ahmed M, Prediletto E, Church SE, Hudson BM, Warren SE, McKeigue PM, Humby F, Bombardieri M, Barnes MR, Lewis MJ and Pitzalis C (2022). Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial. Springer Nature Nature Medicine vol. 28, (6) 1256-1268. 10.1038/s41591-022-01789-0
Yu Z, Zhang J, Zhang Q, Wei S, Shi R, Zhao R, An L, Grose R, Feng D and Wang H (2022). Single‐cell sequencing reveals the heterogeneity and intratumoral crosstalk in human endometrial cancer. Wiley Cell Proliferation vol. 55, (6) 10.1111/cpr.13249
Ghorbani S, Shahrokhtash A, Gautrot JE and Sutherland DS (2022). Protein Ligand Nanopattern Size Selects for Cellular Adhesion via Hemidesmosomes over Focal Adhesions. Wiley Small Methods vol. 6, (6) 10.1002/smtd.202200152
Candarlioglu PL, Dal Negro G, Hughes D, Balkwill F, Harris K, Screen H, Morgan H, David R, Beken S, Guenat O, Rowan W and Amour A (2022). Organ-on-a-chip: current gaps and future directions. Portland Press Biochemical Society Transactions vol. 50, (2) 665-673. 10.1042/BST20200661
Kong D, Peng L, Bosch-Fortea M, Chrysanthou A, Alexis CVJM, Matellan C, Zarbakhsh A, Mastroianni G, del Rio Hernandez A and Gautrot JE (2022). Impact of the multiscale viscoelasticity of quasi-2D self-assembled protein networks on stem cell expansion at liquid interfaces. Elsevier Biomaterials vol. 284, 10.1016/j.biomaterials.2022.121494
Yao Y, Zhou S, Alastruey J, Hao L, Greenwald SE, Zhang Y and Xu L (2022). Estimation of central pulse wave velocity from radial pulse wave analysis. Elsevier Computer Methods and Programs in Biomedicine vol. 219, 10.1016/j.cmpb.2022.106781
Xu L, Zhou S, Wang L, Yao Y, Hao L, Qi L, Han H, Mukkamala R and Greenwald SE (2022). Improving the accuracy and robustness of carotid-femoral pulse wave velocity measurement using a simplified tube-load model. Springer Nature Scientific Reports vol. 12, (1) 10.1038/s41598-022-09256-z
Liu W, Du S, Zhou S, Mei T, Zhang Y, Sun G, Song S, Xu L, Yao Y and Greenwald SE (2022). Noninvasive estimation of aortic pressure waveform based on simplified Kalman filter and dual peripheral artery pressure waveforms. Elsevier Computer Methods and Programs in Biomedicine vol. 219, 10.1016/j.cmpb.2022.106760
Nguyen NT, Jennings J, Milani AH, Martino CDS, Nguyen LTB, Wu S, Mokhtar MZ, Saunders JM, Gautrot JE, Armes SP and Saunders BR (2022). Highly Stretchable Conductive Covalent Coacervate Gels for Electronic Skin. American Chemical Society (Acs) Biomacromolecules vol. 23, (3) 1423-1432. 10.1021/acs.biomac.1c01660
Pundel OJ, Blowes LM and Connelly JT (2022). Extracellular Adhesive Cues Physically Define Nucleolar Structure and Function. Wiley Advanced Science vol. 9, (10) 10.1002/advs.202105545
Shen Y, Kang F, Cheng Y, Zhang K and Sui Y (2022). Numerical and theoretical analysis of fast evaporating sessile droplets with coupled fields. Elsevier International Journal of Thermal Sciences vol. 172, 10.1016/j.ijthermalsci.2021.107284
Cao Y, Liu W, Zhang S, Xu L, Zhu B, Cui H, Geng N, Han H and Greenwald SE (2022). Detection and Localization of Myocardial Infarction Based on Multi-Scale ResNet and Attention Mechanism. Frontiers Frontiers in Physiology vol. 13, 10.3389/fphys.2022.783184
Zardab M, Stasinos K, Grose RP and Kocher HM (2022). The Obscure Potential of AHNAK2. Mdpi Cancers vol. 14, (3) 10.3390/cancers14030528
Mahmood HTNA, Tomas Bort E, Walker AJ, Grose RP and Chioni AM (2022). FGF signalling facilitates cervical cancer progression. Wiley The Federation of European Biochemical Societies (Febs) Journal 10.1111/febs.16331
Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A, Marshall JJT, Rosewell I, Tatari M, Rajeeve V, Khan F, Wang J, Kotantaki P, Tyler EJ, Singh N, Reader CS, Carter EP, Hodivala-Dilke K, Grose RP, Kocher HM, Gavara N, Pearce O, Cutillas P, Marshall JF and Cameron AJM (2022). Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion. Elsevier Cell Reports vol. 38, (4) 10.1016/j.celrep.2021.110227
Whiteford J, Arokiasamy S, Thompson CL and Dufton NP (2022). Novel application of live imaging to determine the functional cell biology of endothelial-to-mesenchymal transition (EndMT) within a liver-on-a-chip platform. Springer Nature In Vitro Models vol. 1, (6) 413-421. 10.1007/s44164-022-00034-9
2021
Sheikh MH, Errede M, d'Amati A, Khan NQ, Fanti S, Loiola RA, McArthur S, Purvis GSD, O'Riordan CE, Ferorelli D, Dell'Erba A, Kieswich J, Reutelingsperger C, Maiorano E, Yaqoob M, Thiemermann C, Baragetti A, Catapano AL, Norata GD, Marelli‐Berg F, Virgintino D and Solito E (2021). Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood‐brain barrier: Therapeutic avenues. Wiley The Faseb Journal vol. 36, (1) 10.1096/fj.202101297r
Hoyles L, Pontifex M, Rodriguez-Ramiro I, Anis-Alavi MA, Jelane KS, Snelling T, Solito E, Fonseca S, Carvalho AL, Carding SR, Muller M, Glen RC, Vauzour D and Mcarthur S (2021). Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide. Biomed Central Microbiome 10.1186/s40168-021-01181-z
Ciancetta A, Gill AK, Ding T, Karlov DS, Chalhoub G, McCormick PJ and Tikhonova IG (2021). Probe Confined Dynamic Mapping for G Protein-Coupled Receptor Allosteric Site Prediction. Acs Central Science vol. 7, (11) 1847-1862. 10.1021/acscentsci.1c00802
Peng L and Gautrot JE (2021). Long term expansion profile of mesenchymal stromal cells at protein nanosheet-stabilised bioemulsions for next generation cell culture microcarriers. Elsevier Materials Today Bio vol. 12, 100159-100159. 10.1016/j.mtbio.2021.100159
Chioni A-M and Grose RP (2021). Biological Significance and Targeting of the FGFR Axis in Cancer. Mdpi Cancers vol. 13, (22) 10.3390/cancers13225681
Raynold AAM, Li D, Chang L and Gautrot JE (2021). Competitive binding and molecular crowding regulate the cytoplasmic interactome of non-viral polymeric gene delivery vectors. Springer Nature Nature Communications vol. 12, (1) 10.1038/s41467-021-26695-w
Woodley K, Dillingh LS, Giotopoulos G, Madrigal P, Tzelepis K, Philippe C, Rattigan K, Asby R, Dembitz V, Magee ASM, Helgason G, Rouault-Pierre K, Vassiliou GS, Huntly BJP and Gallipoli P (2021). Mannose Metabolism Is a Metabolic Vulnerability Unveiled By Standard and Novel Therapies in Acute Myeloid Leukemia. American Society of Hematology Blood vol. 138, (Supplement 1) 10.1182/blood-2021-148489
Alcinesio A, Cazimoglu I, Kimmerly GR, Restrepo Schild V, Krishna Kumar R and Bayley H (2021). Modular Synthetic Tissues from 3D‐Printed Building Blocks. Wiley Advanced Functional Materials vol. 32, (7) 10.1002/adfm.202107773
Nguyen KDQ, Crespo-Ribadeneyra M, Picot O, Colak B and Gautrot JE (2021). Ultrafast Photo-Crosslinking of Thiol–Norbornene Opaque Silicone Elastomer Nanocomposites in Air. American Chemical Society Acs Applied Polymer Materials 10.1021/acsapm.1c00440
Joseph MD, Bort ET, Grose RP, McCormick PJ and Simoncelli S (2021). Quantitative Super-Resolution Imaging for the Analysis of GPCR Oligomerization. Mdpi Biomolecules vol. 11, (10) 10.3390/biom11101503
Alcinesio A, Krishna Kumar R and Bayley H (2021). Functional Multivesicular Structures with Controlled Architecture from 3D‐Printed Droplet Networks. Wiley Chemsystemschem vol. 4, (1) 10.1002/syst.202100036
Paredes-Redondo A, Harley P, Maniati E, Ryan D, Louzada S, Meng J, Kowala A, Fu B, Yang F, Liu P, Marino S, Pourquié O, Muntoni F, Wang J, Lieberam I and Lin YY (2021). Optogenetic modeling of human neuromuscular circuits in Duchenne muscular dystrophy with CRISPR and pharmacological corrections. Science Advances vol. 7, (37) 10.1126/sciadv.abi8787
Maudhoo A, Maharaj A, Buonocore F, Martos-Moreno GA, Argente J, Achermann JC, Chan LF and Metherell LA (2021). Missplicing due to a synonymous, T96= exonic substitution in the T-box transcription factor TBX19 resulting in isolated ACTH deficiency. Bioscientifica Endocrinology Diabetes and Metabolism Case Reports vol. 2021, 21-0128. 10.1530/edm-21-0128
Jomrich G, Kollmann D, Ramazanova D, Ristl R, Grose RP, Ilhan-Mutlu A, Preusser M, Fassnacht C, Tsai Y-C, Guenova E and Schoppmann SF (2021). Expression of programmed cell death protein 1 (PD-1) and programmed cell death 1 ligand (PD-L1) in adenocarcinomas of the gastroesophageal junction change significantly after neoadjuvant treatment. Elsevier European Journal of Surgical Oncology vol. 48, (2) 383-390. 10.1016/j.ejso.2021.08.016
Xu X, Bowen BJ, Gwyther REA, Freeley M, Grigorenko B, Nemukhin AV, Eklöf‐Österberg J, Moth‐Poulsen K, Jones DD and Palma M (2021). Tuning Electrostatic Gating of Semiconducting Carbon Nanotubes by Controlling Protein Orientation in Biosensing Devices. Wiley Angewandte Chemie International Edition vol. 60, (37) 20184-20189. 10.1002/anie.202104044
Carter EP, Roozitalab R, Gibson SV and Grose RP (2021). Tumour microenvironment 3D-modelling: simplicity to complexity and back again. Elsevier Trends in Cancer vol. 7, (11) 1033-1046. 10.1016/j.trecan.2021.06.009
Lu RX, Wang Z, Salsac A-V, Barthès-Biesel D, Wang W and Sui Y (2021). Path selection of a train of spherical capsules in a branched microchannel. Cambridge University Press (Cup) Journal of Fluid Mechanics vol. 923, 10.1017/jfm.2021.571
Megone W, Tang P, Roohpour N and Gautrot JE (2021). Impact of the molecular structure of cationic binders on the rheological and adhesive properties of carboxymethyl cellulose-based coacervate hydrogels. Arkat Usa Arkivoc vol. 2021, (6) 101-119. 10.24820/ark.5550190.p011.516
Freeley M, Gwyther REA, Jones DD and Palma M (2021). DNA-Directed Assembly of Carbon Nanotube–Protein Hybrids. Mdpi Ag Biomolecules 10.3390/biom11070955
Chang L, Yan H, Chang J and Gautrot JE (2021). Cationic Polymer Brush-Coated Bioglass Nanoparticles for the Design of Bioresorbable RNA Delivery Vectors. Elsevier European Polymer Journal 110593-110593. 10.1016/j.eurpolymj.2021.110593
Verbruggen SW, Thompson CL, Duffy MP, Lunetto S, Nolan J, Pearce OMT, Jacobs CR and Knight MM (2021). Mechanical Stimulation Modulates Osteocyte Regulation of Cancer Cell Phenotype. Mdpi Cancers vol. 13, (12) 10.3390/cancers13122906
Liu W, Li Z, Wang Y, Song D, Ji N, Xu L, Mei T, Sun Y and Greenwald SE (2021). Aortic pressure waveform reconstruction using a multi-channel Newton blind system identification algorithm. Elsevier Computers in Biology and Medicine vol. 135, 10.1016/j.compbiomed.2021.104545
Malacrida B, Nichols S, Maniati E, Jones R, Delanie-Smith R, Roozitalab R, Tyler EJ, Thomas M, Boot G, Mackerodt J, Lockley M, Knight MM, Balkwill FR and Pearce OMT (2021). A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion. Elsevier Iscience vol. 24, (6) 10.1016/j.isci.2021.102676
Delaine-Smith RM, Maniati E, Malacrida B, Nichols S, Roozitalab R, Jones RR, Lecker LSM, Pearce OMT, Knight MM and Balkwill FR (2021). Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer. Elsevier Iscience vol. 24, (6) 10.1016/j.isci.2021.102674
Jomrich G, Kollmann D, Wilfing L, Radosavljevic S, Ramazanova D, Ristl R, Grose RP, Ilhan-Mutlu A, Preusser M, Fassnacht C, Tsai Y-C, Guenova E and Schoppmann SF (2021). Programmed death ligand 2 expression plays a limited role in adenocarcinomas of the gastroesophageal junction after preoperative chemotherapy. Springer Nature European Surgery vol. 53, (6) 287-293. 10.1007/s10353-021-00700-4
Smith C, Maharaj AV, Qamar Y, Read J, Williams J, Chan L, Marimuthu V and Metherell L (2021). In Vitro Splicing Assay Proves the Pathogenicity of Intronic Variants in MRAP. Journal of The Endocrine Society vol. 5, (Suppl 1) a85-a86. 10.1210/jendso/bvab048.172
Ismail AS, Goodwin GR, Castrejon-Pita JR, Noyce AJ and Azevedo HS (2021). A novel capsule-based smell test fabricated via coaxial dripping. The Royal Society Journal of The Royal Society Interface vol. 18, (177) 10.1098/rsif.2021.0039
Israeli H, Degtjarik O, Fierro F, Chunilal V, Gill AK, Roth NJ, Botta J, Prabahar V, Peleg Y, Chan LF, Ben-Zvi D, McCormick PJ, Niv MY and Shalev-Benami M (2021). Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling. American Association For The Advancement of Science (Aaas) Science vol. 372, (6544) 808-814. 10.1126/science.abf7958
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Screen HRC, Berk DE, Kadler KE, Ramirez F and Young MF (2015). Tendon Functional Extracellular Matrix. Wiley Journal of Orthopaedic Research® vol. 33, (6) 793-799. 10.1002/jor.22818
Milagre CS, Gopinathan G, Everitt G, Thompson RG, Kulbe H, Zhong H, Hollingsworth RE, Grose R, Bowtell DDL, Hochhauser D and Balkwill FR (2015). Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer. American Association For Cancer Research (Aacr) Cancer Research vol. 75, (7) 1255-1264. 10.1158/0008-5472.can-14-1801
Brewin MP, Birch MJ, Mehta DJ, Reeves JW, Shaw S, Kruse C, Whiteman JR, Hu S, Kenz ZR, Banks HT and Greenwald SE (2015). Characterisation of Elastic and Acoustic Properties of an Agar-Based Tissue Mimicking Material. Springer Nature Annals of Biomedical Engineering vol. 43, (10) 2587-2596. 10.1007/s10439-015-1294-7
Almeida FV, Walko G, McMillan JR, McGrath JA, Wiche G, Barber AH and Connelly JT (2015). The cytolinker plectin regulates nuclear mechanotransduction in keratinocytes. The Company of Biologists Journal of Cell Science vol. 128, (24) 4475-4486. 10.1242/jcs.173435
Fearon AE, Chioni A-M and Grose RP (2015). The FGFR Receptor Family. Receptor Tyrosine Kinases: Family and Subfamilies Springer Nature 10.1007/978-3-319-11888-8_6
2014
Thorpe CT, Chaudhry S, Lei II, Varone A, Riley GP, Birch HL, Clegg PD and Screen HRC (2014). Tendon cell response to cyclic loading. Wiley Scandinavian Journal of Medicine and Science in Sports vol. 25, (4) e381-e391. 10.1111/sms.12333
Carter EP, Fearon AE and Grose RP (2014). Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction. Elsevier Trends in Cell Biology vol. 25, (4) 221-233. 10.1016/j.tcb.2014.11.003
Greco KV, Nalesso G, Kaneva MK, Sherwood J, Iqbal AJ, Moradi-Bidhendi N, Dell'Accio F and Perretti M (2014). Analyses on the mechanisms that underlie the chondroprotective properties of calcitonin. Biochem Pharmacol vol. 91, (3) 348-358. 10.1016/j.bcp.2014.07.034
Kaneva MK, Kerrigan MJP, Grieco P, Curley GP, Locke IC and Getting SJ (2014). Melanocortin peptides protect chondrocytes from mechanically induced cartilage injury. Elsevier Biochemical Pharmacology vol. 92, (2) 336-347. 10.1016/j.bcp.2014.08.019
Coleman SJ, Bruce C, Chioni A-M, Kocher HM and Grose RP (2014). The ins and outs of fibroblast growth factor receptor signalling. Clin Sci (Lond) vol. 127, (4) 217-231. 10.1042/CS20140100
Coleman SJ, Watt J, Arumugam P, Solaini L, Carapuca E, Ghallab M, Grose RP and Kocher HM (2014). Pancreatic cancer organotypics: High throughput, preclinical models for pharmacological agent evaluation. World J Gastroenterol vol. 20, (26) 8471-8481. 10.3748/wjg.v20.i26.8471
Costa P, Gautrot JE and Connelly JT (2014). Directing cell migration using micropatterned and dynamically adhesive polymer brushes. Acta Biomater vol. 10, (6) 2415-2422. 10.1016/j.actbio.2014.01.029
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljević N, Chaplin T, Xue L, Xu M, Foster JM, Karnam SS, James SY, Chioni A-M, Gould D, Lorincz AT, Oliver RTD, Chelala C, Thomas GM, Shipley JM, Mather SJ, Berney DM, Young BD and Lu Y-J (2014). Identification of ZDHHC14 as a novel human tumour suppressor gene. J Pathol vol. 232, (5) 566-577. 10.1002/path.4327
Coleman SJ, Chioni A-M, Ghallab M, Anderson RK, Lemoine NR, Kocher HM and Grose RP (2014). Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion. Embo Mol Med vol. 6, (4) 467-481. 10.1002/emmm.201302698
Shah FA, Brauer DS, Wilson RM, Hill RG and Hing KA (2014). Influence of cell culture medium composition on in vitro dissolution behavior of a fluoride-containing bioactive glass. Journal of Biomedical Materials Research - Part A vol. 102, (3) 647-654. 10.1002/jbm.a.34724
Fearon AE and Grose RP (2014). Grb-ing receptor activation by the tail. Nat Struct Mol Biol vol. 21, (2) 113-114. 10.1038/nsmb.2767
Banks HT, Hu S, Kenz ZR, Kruse C, Shaw S, Whiteman J, Brewin MP, Greenwald SE and Birch MJ (2014). MODEL VALIDATION FOR A NONINVASIVE ARTERIAL STENOSIS DETECTION PROBLEM. Mathematical Biosciences and Engineering vol. 11, (3) 427-448. 10.3934/mbe.2014.11.427
2013
Fearon AE, Gould CR and Grose RP (2013). FGFR signalling in women's cancers. Int J Biochem Cell Biol vol. 45, (12) 2832-2842. 10.1016/j.biocel.2013.09.017
Shafat M, Rajakumar K, Syme H, Buchholz N and Knight MM (2013). Stent encrustation in feline and human artificial urine: does the low molecular weight composition account for the difference? Urolithiasis vol. 41, (6) 481-486. 10.1007/s00240-013-0608-1
Cai H, Depoil D, Palma M, Sheetz MP, Dustin ML and Wind SJ (2013). Bifunctional nanoarrays for probing the immune response at the single-molecule level. J Vac Sci Technol B Nanotechnol Microelectron vol. 31, (6) 10.1116/1.4823764
Guasti L, Candy Sze WC, McKay T, Grose R and King PJ (2013). FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development. Mol Cell Endocrinol vol. 371, (1-2) 182-188. 10.1016/j.mce.2013.01.014
Campion CR, Ball SL, Clarke DL and Hing KA (2013). Microstructure and chemistry affects apatite nucleation on calcium phosphate bone graft substitutes. Journal of Materials Science: Materials in Medicine vol. 24, (3) 597-610. 10.1007/s10856-012-4833-x
Galavotti S, Bartesaghi S, Faccenda D, Shaked-Rabi M, Sanzone S, McEvoy A, Dinsdale D, Condorelli F, Brandner S, Campanella M, Grose R, Jones C and Salomoni P (2013). The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. Oncogene vol. 32, (6) 699-712. 10.1038/onc.2012.111
Mafina M-K, Hing KA and Sullivan AC (2013). Development of novel fluorescent probes for the analysis of protein interactions under physiological conditions with medical devices. Langmuir vol. 29, (5) 1420-1426. 10.1021/la304244s
Legerlotz K, Jones GC, Screen HRC and Riley GP (2013). Cyclic loading of tendon fascicles using a novel fatigue loading system increases interleukin-6 expression by tenocytes. Scandinavian Journal of Medicine and Science in Sports vol. 23, (1) 31-37. 10.1111/j.1600-0838.2011.01410.x
Robbez-Masson LJ, Bödör C, Jones JL, Hurst HC, Fitzgibbon J, Hart IR and Grose RP (2013). Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing. Plos One vol. 8, (11) 10.1371/journal.pone.0078839
Greenwald SE, Banks HT, Birch MJ, Brewin MP, Hu S, Kenz ZR, Kruse C, Mehta D, Reeves J, Shaw S and Whiteman JR (2013). Acoustic localisation of coronary artery stenosis: Wave propagation in soft tissue mimicking gels. Springer Nature Artery Research vol. 7, (3-4) 10.1016/j.artres.2013.10.081
2012
Meyer M, Müller A-K, Yang J, Moik D, Ponzio G, Ornitz DM, Grose R and Werner S (2012). FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin. J Cell Sci vol. 125, (Pt 23) 5690-5701. 10.1242/jcs.108167
Brewin M, Greenwald , Shaw S, Kruse C, Whiteman and Birch M (2012). CHARACTERISATION OF AGAROSE GEL AS A TISSUE MIMIC MATERIAL (TMM) FOR USE IN AN ANTHROPOMORPHIC TEST OBJECT INVESTIGATING THE ACOUSTIC LOCALISATION OF CORONARY STENOSIS. Elsevier Journal of Biomechanics vol. 45, 10.1016/s0021-9290(12)70140-9
Chioni A-M and Grose R (2012). FGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior. J Cell Biol vol. 197, (6) 801-817. 10.1083/jcb.201108077
Tsang SM, Brown L, Lin K, Liu L, Piper K, O'Toole EA, Grose R, Hart IR, Garrod DR, Fortune F and Wan H (2012). Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris. J Pathol vol. 227, (1) 81-93. 10.1002/path.3982
Driskell RR, Juneja VR, Connelly JT, Kretzschmar K, Tan DW-M and Watt FM (2012). Clonal growth of dermal papilla cells in hydrogels reveals intrinsic differences between Sox2-positive and -negative cells in vitro and in vivo. J Invest Dermatol vol. 132, (4) 1084-1093. 10.1038/jid.2011.428
Trappmann B, Gautrot JE, Connelly JT, Strange DGT, Li Y, Oyen ML, Cohen Stuart MA, Boehm H, Li B, Vogel V, Spatz JP, Watt FM and Huck WTS (2012). Extracellular-matrix tethering regulates stem-cell fate. Nature Materials 10.1038/nmat3339
Jarosz M, Robbez-Masson L, Chioni A-M, Cross B, Rosewell I and Grose R (2012). Fibroblast growth factor 22 is not essential for skin development and repair but plays a role in tumorigenesis. Plos One vol. 7, (6) 10.1371/journal.pone.0039436
2011
Guth K, Campion C, Buckland T and Hing KA (2011). Effects of serum protein on ionic exchange between culture medium and microporous hydroxyapatite and silicate-substituted hydroxyapatite. Journal of Materials Science: Materials in Medicine vol. 22, (10) 2155-2164. 10.1007/s10856-011-4409-1
Palma M, Abramson JJ, Gorodetsky AA, Penzo E, Gonzalez RL, Sheetz MP, Nuckolls C, Hone J and Wind SJ (2011). Selective biomolecular nanoarrays for parallel single-molecule investigations. J Am Chem Soc vol. 133, (20) 7656-7659. 10.1021/ja201031g
Schvartzman M, Palma M, Sable J, Abramson J, Hu X, Sheetz MP and Wind SJ (2011). Nanolithographic control of the spatial organization of cellular adhesion receptors at the single-molecule level. Nano Lett vol. 11, (3) 1306-1312. 10.1021/nl104378f
Palma M, Abramson JJ, Gorodetsky AA, Nuckolls C, Sheetz MP, Wind SJ and Hone J (2011). Controlled confinement of DNA at the nanoscale: nanofabrication and surface bio-functionalization. Methods Mol Biol vol. 749, 169-185. 10.1007/978-1-61779-142-0_12
Penzo E, Wang R, Palma M and Wind SJ (2011). Selective placement of DNA origami on substrates patterned by nanoimprint lithography. Journal of Vacuum Science & Technology B vol. 29, (6) 10.1116/1.3646900
2010
Connelly JT, Gautrot JE, Trappmann B, Tan DWM, Donati G, Huck WTS and Watt FM (2010). Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions. Nature Cell Biology vol. 12, (7) 711-718. 10.1038/ncb2074
Connelly JT, Vanderploeg EJ, Mouw JK, Wilson CG and Levenston ME (2010). Tensile loading modulates bone marrow stromal cell differentiation and the development of engineered fibrocartilage constructs. Tissue Eng Part A vol. 16, (6) 1913-1923. 10.1089/ten.TEA.2009.0561
Guth K, Campion C, Buckland T and Hing KA (2010). Surface physiochemistry affects protein adsorption to stoichiometric and silicate-substituted microporous hydroxyapatites. Advanced Engineering Materials vol. 12, (4) 10.1002/adem.200980026
Yang J, Meyer M, Müller A-K, Böhm F, Grose R, Dauwalder T, Verrey F, Kopf M, Partanen J, Bloch W, Ornitz DM and Werner S (2010). Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis. J Cell Biol vol. 188, (6) 935-952. 10.1083/jcb.200910126
Screen HRC, Byers S, Lynn AD, Nguyen V, Patel D and Bryant SJ (2010). Characterization of a novel fiber composite material for mechanotransduction research of fibrous connective tissues. Advanced Functional Materials vol. 20, (5) 738-747. 10.1002/adfm.200901711
Turner N and Grose R (2010). Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer vol. 10, (2) 116-129. 10.1038/nrc2780
Chioni A-M, Shao D, Grose R and Djamgoz MBA (2010). Protein kinase A and regulation of neonatal Nav1.5 expression in human breast cancer cells: activity-dependent positive feedback and cellular migration. Int J Biochem Cell Biol vol. 42, (2) 346-358. 10.1016/j.biocel.2009.11.021
Guth K, Campion C, Buckland T and Hing KA (2010). Effect of silicate-substitution on attachment and early development of human osteoblast-like cells seeded on microporous hydroxyapatite discs. Advanced Engineering Materials vol. 12, (1-2) 10.1002/adem.200980003
D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V, Martinez D, Aubyn D, Grose R, Thomas GJ, Spencer-Dene B, Zicha D, Davies D, Tybulewicz V and Hodivala-Dilke KM (2010). Regulation of lymphatic-blood vessel separation by endothelial Rac1 (vol 136, pg 4043, 2009). Development vol. 137, (2) 359-359. 10.1242/dev.047597
Tsang SM, Liu L, Teh M-T, Wheeler A, Grose R, Hart IR, Garrod DR, Fortune F and Wan H (2010). Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src. Plosone Plos One vol. 5, (12) 10.1371/journal.pone.0014211
2009
Chioni A-M and Grose R (2009). Negative regulation of fibroblast growth factor 10 (FGF-10) by polyoma enhancer activator 3 (PEA3). Eur J Cell Biol vol. 88, (7) 371-384. 10.1016/j.ejcb.2009.01.004
2008
Chioni A-M and Grose R (2008). Organotypic modelling as a means of investigating epithelial-stromal interactions during tumourigenesis. Fibrogenesis Tissue Repair vol. 1, (1) 10.1186/1755-1536-1-8
Connelly JT, García AJ and Levenston ME (2008). Interactions between integrin ligand density and cytoskeletal integrity regulate BMSC chondrogenesis. J Cell Physiol vol. 217, (1) 145-154. 10.1002/jcp.21484
Rashid N, Harding I, Buckland T and HING KA (2008). Nano-scale manipulation of silicate-substituted apatite chemistry impacts surface charge, hydrophilicity, protein adsorption and cell attachment., Editors: Meenan BJ and Boyd AR. International Journal of Nano and Biomaterials vol. 1, (3) 299-319. 10.1504/IJNBM.2008.016877
2007
Grose R, Fantl V, Werner S, Chioni A-M, Jarosz M, Rudling R, Cross B, Hart IR and Dickson C (2007). The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development. Embo J vol. 26, (5) 1268-1278. 10.1038/sj.emboj.7601583
Connelly JT, García AJ and Levenston ME (2007). Inhibition of in vitro chondrogenesis in RGD-modified three-dimensional alginate gels. Biomaterials vol. 28, (6) 1071-1083. 10.1016/j.biomaterials.2006.10.006
2005
Grose R and Dickson C (2005). Fibroblast growth factor signaling in tumorigenesis. Cytokine Growth Factor Rev vol. 16, (2) 179-186. 10.1016/j.cytogfr.2005.01.003
Reynolds LE, Conti FJ, Lucas M, Grose R, Robinson S, Stone M, Saunders G, Dickson C, Hynes RO, Lacy-Hulbert A and Hodivala-Dilke K (2005). Accelerated re-epithelialization in beta3-integrin-deficient- mice is associated with enhanced TGF-beta1 signaling. Nat Med vol. 11, (2) 167-174. 10.1038/nm1165
2004
Grose R and Werner S (2004). Wound-healing studies in transgenic and knockout mice. Mol Biotechnol vol. 28, (2) 147-166. 10.1385/MB:28:2:147
Zhang HB, Dessimoz J, Beyer TA, Krampert M, Williams LT, Werner S and Grose R (2004). Fibroblast growth factor receptor 1-lllb is dispensable for skin morphogenesis and wound healing. Eur J Cell Biol vol. 83, (1) 3-11. 10.1078/0171-9335-00355
Grose R (2004). Common ground in the transcriptional profiles of wounds and tumors. Genome Biol vol. 5, (6) 10.1186/gb-2004-5-6-228
2003
Young P, Boussadia O, Halfter H, Grose R, Berger P, Leone DP, Robenek H, Charnay P, Kemler R and Suter U (2003). E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles. Embo J vol. 22, (21) 5723-5733. 10.1093/emboj/cdg560
Petiot A, Conti FJA, Grose R, Revest J-M, Hodivala-Dilke KM and Dickson C (2003). A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning. Development vol. 130, (22) 5493-5501. 10.1242/dev.00788
Grose R (2003). Epithelial migration: open your eyes to c-Jun. Curr Biol vol. 13, (17) R678-R680. 10.1016/s0960-9822(03)00607-9
Beyer TA, Werner S, Dickson C and Grose R (2003). Fibroblast growth factor 22 and its potential role during skin development and repair. Exp Cell Res vol. 287, (2) 228-236. 10.1016/S0014-4827(03)00139-3
Werner S and Grose R (2003). Regulation of wound healing by growth factors and cytokines. Physiol Rev vol. 83, (3) 835-870. 10.1152/physrev.2003.83.3.835
Martin P, D'Souza D, Martin J, Grose R, Cooper L, Maki R and McKercher SR (2003). Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells. Curr Biol vol. 13, (13) 1122-1128. 10.1016/s0960-9822(03)00396-8
Grose R and Werner S (2003). Wound Healing Studies in Transgenic and Knockout Mice. Wound Healing Springer Nature 10.1385/1-59259-332-1:191
Grose R and Werner S (2003). Wound healing studies in transgenic and knockout mice. A review. Methods Mol Med vol. 78, 191-216. 10.1385/1-59259-332-1:191
2002
Wood W, Jacinto A, Grose R, Woolner S, Gale J, Wilson C and Martin P (2002). Wound healing recapitulates morphogenesis in Drosophila embryos. Nat Cell Biol vol. 4, (11) 907-912. 10.1038/ncb875
Grose R, Werner S, Kessler D, Tuckermann J, Huggel K, Durka S and Reichardt HM (2002). A role for endogenous glucocorticoids in wound repair. Embo Rep vol. 3, (6) 575-582. 10.1093/embo-reports/kvf119
Grose R, Hutter C, Bloch W, Thorey I, Watt FM, Fässler R, Brakebusch C and Werner S (2002). A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair. Development vol. 129, (9) 2303-2315. 10.1242/dev.129.9.2303
Grose R and Werner S (2002). An aPPARently protective mechanism for keratinocytes in wounded skin. Trends Mol Med vol. 8, (4) 149-151. 10.1016/s1471-4914(02)02312-2
Grose R, Harris BS, Cooper L, Topilko P and Martin P (2002). Immediate early genes krox-24 and krox-20 are rapidly up-regulated after wounding in the embryonic and adult mouse. Dev Dyn vol. 223, (3) 371-378. 10.1002/dvdy.10064
2000
Bloch W, Huggel K, Sasaki T, Grose R, Bugnon P, Addicks K, Timpl R and Werner S (2000). The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing. Wiley The Faseb Journal vol. 14, (15) 2373-2376. 10.1096/fj.00-0490fje
Brakebusch C, Grose R, Quondamatteo F, Ramirez A, Jorcano JL, Pirro A, Svensson M, Herken R, Sasaki T, Timpl R, Werner S and Fässler R (2000). Skin and hair follicle integrity is crucially dependent on β1 integrin expression on keratinocytes. Springer Nature The Embo Journal vol. 19, (15) 3990-4003. 10.1093/emboj/19.15.3990
1999
Grose R and Martin P (1999). Parallels between wound repair and morphogenesis in the embryo. Elsevier Seminars in Cell and Developmental Biology vol. 10, (4) 395-404. 10.1006/scdb.1999.0326