Publications
The following journal papers published by the members of the CPM, specifically relate to the development and/or use of predictive in vitro models.
- Investigating iRHOM2-Associated Transcriptional Changes in Tylosis With Esophageal Cancer
Murtough S, Babu D, Webb CM, Picard HLD, McGinty LA, Pink R, Silver AR, Smart HL et al.
Gastro Hep Advances, Elsevier vol. 3 (3), 385-395.
26-12-2023 - Comparison of multiple modalities for drug response prediction with learning curves using neural networks and XGBoost
Branson N, Cutillas PR, Bessant C
Bioinformatics Advances, Oxford University Press (Oup) vol. 4 (1)
23-12-2023 - Identification of novel immune cell signature in gastroesophageal reflux disease: altered mucosal mast cells and dendritic cell profile
Ustaoglu A, Daudali FA, D’afflitto M, Murtough S, Lee C, Moreno E, Blaydon DC, Kelsell DP et al.
Frontiers in Immunology, Frontiers vol. 14
30-11-2023 - Controlled electroactive release from solid-state conductive elastomer electrodes
Chapman CAR, Fernandez-Patel S, Jahan N, Cuttaz EA, Novikov A, Goding JA, Green RA
Materials Today Bio, Elsevier vol. 23
28-11-2023 - Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion
Aguirre GA, Goulart MR, Bank BPT, Dalli J, Kocher HM
Frontiers in Immunology, Frontiers vol. 14
16-11-2023 - A Novel Primary Cilium‐Mediated Mechanism Through which Osteocytes Regulate Metastatic Behavior of Both Breast and Prostate Cancer Cells
Verbruggen SW, Nolan J, Duffy MP, Pearce OMT, Jacobs CR, Knight MM
Advanced Science, Wiley vol. 11 (2), 2305842-2305842.
15-11-2023 - Mucosal Immunity to Gut Fungi in Health and Inflammatory Bowel Disease
Carlson SL, Mathew L, Savage M, Kok K, Lindsay JO, Munro CA, McCarthy NE
Journal of Fungi, Mdpi vol. 9 (11)
14-11-2023 - Generation of glucocorticoid-producing cells derived from human pluripotent stem cells
Ruiz-Babot G, Eceiza A, Abollo-Jiménez F, Malyukov M, Carlone DL, Borges K, Da Costa AR, Qarin S et al.
Cell Reports Methods, Elsevier vol. 3 (11)
01-11-2023 - CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells
Samain R, Maiques O, Monger J, Lam H, Candido J, George S, Ferrari N, Lunetto S et al.
Science Advances, American Association For The Advancement of Science (Aaas) vol. 9 (42)
18-10-2023 - Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment
Thompson CL, Hopkins T, Bevan C, Screen HRC, Wright KT, Knight MM
Biomedical Materials, Iop Publishing vol. 18 (6)
10-10-2023 - P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes
Beltran-Lobo P, Hughes MM, Troakes C, Croft CL, Rupawala H, Jutzi D, Ruepp M-D, Jimenez-Sanchez M et al.
Brain Behavior and Immunity, Elsevier vol. 114, 414-429.
15-09-2023 - Inferring Compensatory Kinase Networks in Yeast using Prolog
Elder GA, Bessant C
Electronic Proceedings in Theoretical Computer Science, Open Publishing Association vol. 385, 260-273.
12-09-2023 - Cx43 regulates mechanotransduction mechanisms in human preterm amniotic membrane defects
Costa E, Thrasivoulou C, Becker DL, Deprest JA, David AL, Chowdhury TT
Prenatal Diagnosis, Wiley vol. 43 (10), 1284-1295.
30-08-2023 - The longevity and reversibility of quiescence in Schizosaccharomyces pombe are dependent upon the HIRA histone chaperone
Gal C, Cochrane GA, Morgan BA
Cell Cycle, Taylor & Francis vol. 22 (17), 1921-1936.
27-08-2023 - Ribosomal Biogenesis and Heterogeneity in Development, Disease, and Aging
Islam RA, Rallis C
Epigenomes, Mdpi vol. 7 (3)
11-08-2023 - Polyether ether ketone coated with nanohydroxyapatite/graphene oxide composite promotes bioactivity and antibacterial activity at the surface of the material
Al‐Noaman A, Rawlinson SCF
European Journal of Oral Sciences, Wiley vol. 131 (5-6)
02-08-2023 - Core–Shell-Structured Electrorheological Fluid with a Polarizability-Tunable Nanocarbon Shell for Enhanced Stimuli-Responsive Activity
Chen S, Cheng Y, Zhao Z, Zhang K, Hao T, Sui Y, Wang W, Zhao J et al.
Acs Applied Materials & Interfaces, American Chemical Society (Acs) vol. 15 (29), 35741-35749.
14-07-2023 - O06 Exploring host–microbiome–immune interactions using singular and multispecies inoculations in optimized 3D skin models
McPolin-Hall E, Stephen A, Pardieu C, Allaker R, Philpott M, Bhogal R, Pople J, Hannen R
British Journal of Dermatology, Oxford University Press (Oup) vol. 189 (1), e6-e6.
07-07-2023 - Constriction imposed by basement membrane regulates developmental cell migration
López EM, Kabanova A, Winkel A, Franze K
Plos Biology, Public Library of Science (Plos) vol. 21 (6)
28-06-2023 - Community detection in empirical kinase networks identifies new potential members of signalling pathways
De Los Angeles Colomina Basanta C, Bazzi M, Hijazi M, Bessant C, Cutillas PR
Plos Computational Biology, Public Library of Science (Plos) vol. 19 (6)
23-06-2023 - The gut microbe‐derived methylamine TMAO protects against neuroinflammation through restraint of pro‐inflammatory glial behaviour
McArthur S
Alzheimer's & Dementia, Wiley vol. 19 (S1)
16-06-2023 - H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function
Pal D, Patel M, Boulet F, Sundarraj J, Grant OA, Branco MR, Basu S, Santos SDM et al.
Nature Structural & Molecular Biology, Springer Nature vol. 30 (7), 935-947.
12-06-2023 - Transient deformation of a viscoelastic capsule in a cross-slot microchannel: effects of inertia and membrane viscosity
Lu RX, Guo ZY, Yu P, Sui Y
Journal of Fluid Mechanics, Cambridge University Press (Cup) vol. 962
03-05-2023 - 769 Reduced expression of PPOX, the variegate porphyria gene, causes intrinsic pathological changes to keratinocytes
Smith CJ, Chan L, Metherell LA
Journal of Investigative Dermatology, Elsevier vol. 143 (5)
01-05-2023 - DLL4 promotes partial endothelial-to-mesenchymal transition at atherosclerosis-prone regions of arteries
Li X, Souilhol C, Canham L, Jia X, Diagbouga M, Ayllon BT, Serbanovic-Canic J, Evans PC
Vascular Pharmacology, Elsevier vol. 150
01-05-2023 - 910 Exploring host-microbiome interactions in optimised 3D skin models
McPolin-Hall E, Stephens A, Pardieu C, Allaker R, Philpott M, Pople J, Hannen R
Journal of Investigative Dermatology, Elsevier vol. 143 (5)
01-05-2023 - Development of an in vitro microfluidic model to study the role of microenvironmental cells in oral cancer metastasis
Scemama A, Tailor A, Di Cio S, Dibble M, Gautrot J, Biddle A
F1000research, F1000research vol. 12
25-04-2023 - The impact of pericytes on the stability of microvascular networks in response to nanoparticles
Dibble M, Di Cio’ S, Luo P, Balkwill F
Scientific Reports, Springer Nature vol. 13 (1)
07-04-2023 - Abstract 4576: 3D in vitro models uncover malignant cell intrinsic and extrinsic mechanisms of CAR-T cell resistance in high grade serous ovarian cancer
Joy JD, Malacrida B, Laforêts F, Kotantaki P, Maniati E, Hopkins S, Garrobo-Calleja I, Gautrot J et al.
Cancer Research, American Association For Cancer Research (Aacr) vol. 83 (7_Supplement), 4576-4576.
04-04-2023 - Engineering Biofouling Resistant Materials Through the Systematic Adaptation of Surface Morphology
Sadler E, Stephen AS, Allaker RP, Crick CR
Advanced Materials Interfaces, Wiley vol. 10 (12)
28-03-2023 - A method for real-time mechanical characterisation of microcapsules
Guo Z, Lin T, Jing D, Wang W, Sui Y
Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 22 (4), 1209-1220.
24-03-2023 - Growth of mesenchymal stem cells at the surface of silicone, mineral and plant-based oils
Peng L, Nadal C
Biomedical Materials, Iop Publishing vol. 18 (3)
17-03-2023 - 3D Compartmentalised Human Pluripotent Stem Cell–derived Neuromuscular Co-cultures
Harley P, Paredes-Redondo A, Grenci G, Viasnoff V, Lin Y-Y, Lieberam I
Bio-Protocol vol. 13 (5), e4624-e4624.
05-03-2023 - Ichthyosis linked to sphingosine 1-phosphate lyase insufficiency is due to aberrant sphingolipid and calcium regulation
Smith CJ, Williams JL, Hall C, Casas J, Caley MP, O'Toole EA, Prasad R, Metherell LA
Journal of Lipid Research, Elsevier vol. 64 (4)
02-03-2023 - TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression
Gibson SV, Tomas Bort E, Rodríguez-Fernández L, Allen MD, Gomm JJ, Goulding I, auf dem Keller U, Agnoletto A et al.
Npj Breast Cancer, Springer Nature vol. 9 (1)
02-03-2023 - A computational model for the transit of a cancer cell through a constricted microchannel
Wang Z, Lu R, Wang W, Tian FB, Feng JJ, Sui Y
Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 22 (4), 1129-1143.
28-02-2023 - Mesenchymal Stem Cells Sense the Toughness of Nanomaterials and Interfaces
Peng L, Matellan C, Bosch‐Fortea M, Gonzalez‐Molina J, Frigerio M, Salentinig S, del Rio Hernandez A, Gautrot JE
Advanced Healthcare Materials, Wiley vol. 12 (13)
21-02-2023 - Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al.
Jci Insight, American Society For Clinical Investigation vol. 8 (3)
08-02-2023 - Interplays of AMPK and TOR in Autophagy Regulation in Yeast
Alao J-P, Legon L, Dabrowska A, Tricolici A-M
Cells, Mdpi vol. 12 (4)
04-02-2023 - Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening
Hayat A, Carter EP, King HW, Ors A, Doe A, Teijeiro SA, Charrot S, Godinho S et al.
Disease Models & Mechanisms, The Company of Biologists vol. 16 (2)
01-02-2023 - Mechanical Evaluation of Hydrogel–Elastomer Interfaces Generated through Thiol–Ene Coupling
Nguyen KDQ, Dejean S, Nottelet B
Acs Applied Polymer Materials, American Chemical Society (Acs) vol. 5 (2), 1364-1373.
30-01-2023 - A novel bioactive glass/graphene oxide composite coating for a polyether ether ketone‐based dental implant
Al‐Noaman A
European Journal of Oral Sciences, Wiley vol. 131 (2)
27-01-2023 - Co-Surfactant-Free Bioactive Protein Nanosheets for the Stabilization of Bioemulsions Enabling Adherent Cell Expansion
Chrysanthou A, Bosch-Fortea M, Gautrot JE
Biomacromolecules, American Chemical Society (Acs) vol. 24 (10), 4465-4477.
23-01-2023 - Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK
Nolan J, Pearce OMT, Screen HRC, Knight MM, Verbruggen SW
Cancers, Mdpi vol. 15 (3)
19-01-2023 - Supercharged Protein Nanosheets for Cell Expansion on Bioemulsions
Chrysanthou A, Kanso H, Zhong W
Acs Applied Materials & Interfaces, American Chemical Society (Acs) vol. 15 (2), 2760-2770.
04-01-2023 - A host-gut microbial amino acid co-metabolite, p-cresol glucuronide, promotes blood-brain barrier integrity in vivo.
Stachulski AV, Knausenberger TB-A, Shah SN, Hoyles L, McArthur S
Tissue Barriers vol. 11 (1), 2073175-2073175.
02-01-2023 - A guide to functionalisation and bioconjugation strategies to surface-initiated polymer brushes
Neri-Cruz CE, Teixeira FME
Chemical Communications, Royal Society of Chemistry (Rsc) vol. 59 (49), 7534-7558.
01-01-2023 - Titanium Dioxide/Graphene Oxide Composite Coatings for 316 Stainless Steel Dental Implants.
Al-Noaman AS
European Journal of Prosthodontics and Restorative Dentistry vol. 31 (4), 358-372.
01-01-2023