Prof Qingzhong Xiao

Qingzhong Xiao
MD, PhD

Professor of Stem Cell and Cardiovascular Disease

William Harvey Research Institute
Faculty of Medicine and Dentistry, Queen Mary University of London
ORCiD

Research

Stem cell, Vascular cell biology, Vascular disease, Non-coding RNAs, Molecular biology, Vascular development

Cardiovascular Models

Interests

2D (primary vascular smooth muscle cells and endothelial cells) or 3D (vascular organoids) in vitro models and several animal models of vascular diseases (atherosclerosis, post-angioplasty restenosis, Aortic aneurysm & dissection, vascular calcification) to study the aetiologies & therapeutic interventions of vascular diseases.

Publications

Publications of specific relevance to Predictive in vitro Models

2023

Meng X, Wu TG, Lou QY, Niu KY, Jiang L, Xiao QZ, Xu T and Zhang L (2023). Optimization of CRISPR–Cas system for clinical cancer therapy. Bioengineering and Translational Medicine  vol. 8, (2) 10.1002/btm2.10474
Chen K, Mou R, Zhu P, Xu X, Wang H, Jiang L, Hu Y, Hu X, Ma L, Xiao Q and Xu Q (2023). The Effect of Lymphangiogenesis in Transplant Arteriosclerosis. Circulation  vol. 147, (6) 482-497. 10.1161/CIRCULATIONAHA.122.060799
Sellahewa SG, Li JY and Xiao Q (2023). Updated Perspectives on Direct Vascular Cellular Reprogramming and Their Potential Applications in Tissue Engineered Vascular Grafts. Journal of Functional Biomaterials  vol. 14, (1) 10.3390/jfb14010021
Efovi D and Xiao Q (2023). Noncoding RNAs in Vascular Cell Biology and Restenosis. Biology  vol. 12, (1) 10.3390/biology12010024

2022

Karamanavi E, McVey DG, Van Der Laan SW, Stanczyk PJ, Morris GE, Wang Y, Yang W, Chan K, Poston RN, Luo J, Zhou X, Gong P, Jones PD, Cao J, Kostogrys RB, Webb TR, Pasterkamp G, Yu H, Xiao Q, Greer PA, Stringer EJ, Samani NJ and Ye S (2022). The FES Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis. Circulation Research  vol. 131, (12) 1004-1017. 10.1161/CIRCRESAHA.122.321146
Swiatlowska P, Sit B, Feng Z, Marhuenda E, Zhou X, Xiao Q, Shanahan C, Yu C-H and Iskratsch T (2022). Mechanoregulation of vascular smooth muscle cells phenotype in atherosclerosis. Journal of Molecular and Cellular Cardiology  vol. 173, 41-42. 10.1016/j.yjmcc.2022.08.083
Zhou K, Chen H, Wang XY, Xu YM, Liao YF, Qin YY, Ge XW, Zhang TT, Fang ZL, Fu BB, Xiao QZ, Zhu FQ, Chen SR, Liu XS, Luo QC and Gao S (2022). Targeted pharmacokinetics and bioinformatics screening strategy reveals JAK2 as the main target for Xin-Ji-Er-Kang in treatment of MIR injury. Biomedicine and Pharmacotherapy  vol. 155, 10.1016/j.biopha.2022.113792
Zhang C, Niu K, Ren M, Zhou X, Yang Z, Yang M, Wang X, Luo J, Shao Y, Chen D, Gao S, Ge S, Wu Q and Xiao Q (2022). Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model. Cells  vol. 11, (20) 10.3390/cells11203218
Yang S, Wang C, Ruan C, Chen M, Cao R, Sheng L, Chang N, Xu T, Zhao P, Liu X, Zhu F, Xiao Q and Gao S (2022). Novel Insights into the Cardioprotective Effects of Calcitriol in Myocardial Infarction. Cells  vol. 11, (10) 10.3390/cells11101676
Swiatlowska P, Sit BHM, Zhen F, Marhuenda E, Xanthis I, Zingaro S, Ward M, Zhou X, Xiao Q, Shanahan C, Jones G, Yu C-H and Iskratsch T (2022). Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching. American Association For The Advancement of Science  Science Advances  10.1126/sciadv.abm3471
Pan M, Cheng ZW, Huang CG, Ye ZQ, Sun LJ, Chen H, Fu BB, Zhou K, Fang ZR, Wang ZJ, Xiao QZ, Liu XS, Zhu FQ and Gao S (2022). Long-term exposure to copper induces mitochondria-mediated apoptosis in mouse hearts. Ecotoxicology and Environmental Safety  vol. 234, 10.1016/j.ecoenv.2022.113329
Yao L, Hao Y, Wen G, Xiao Q, Wu P, Wang J and Liu J (2022). Induction of Heme Oxygenase-1 Modifies the Systemic Immunity and Reduces Atherosclerotic Lesion Development in ApoE Deficient Mice. Frontiers in Pharmacology  vol. 13, 10.3389/fphar.2022.809469
An W, Luong LA, Bowden NP, Yang M, Wu W, Zhou X, Liu C, Niu K, Luo J, Zhang C, Sun X, Poston R, Zhang L, Evans PC and Xiao Q (2022). Cezanne is a critical regulator of pathological arterial remodelling by targeting β-catenin signalling. Cardiovascular Research  vol. 118, (2) 638-653. 10.1093/cvr/cvab056
Yan Y, Xu Y, Yang X, Li Z, Niu K, Liu C, Zhao M, Xiao Q and Wu W (2022). Electron Transfer Flavoprotein (ETF) α Controls Blood Vessel Development by Regulating Endothelial Mitochondrial Bioenergetics and Oxygen Consumption. Oxidative Medicine and Cellular Longevity  vol. 2022, 10.1155/2022/7969916

2021

Yang M, Chen Q, Mei L, Wen G, An W, Zhou X, Niu K, Liu C, Ren M, Sun K, Xiao Q and Zhang L (2021). Neutrophil elastase promotes neointimal hyperplasia by targeting toll-like receptor 4 (TLR4)–NF-κB signalling. British Journal of Pharmacology  vol. 178, (20) 4048-4068. 10.1111/bph.15583
Zhang C, Niu K, Lian P, Hu Y, Shuai Z, Gao S, Ge S, Xu T, Xiao Q and Chen Z (2021). Pathological Bases and Clinical Application of Long Noncoding RNAs in Cardiovascular Diseases. Hypertension (Dallas, Tex. : 1979)  vol. 78, (1) 16-29. 10.1161/HYPERTENSIONAHA.120.16752
Hu LL, Zou K, Chen Y, Wu LJ, Cao J, Xiong XY, Wang L, Cheng XS, Xiao QZ and Yang RQ (2021). Functional role and molecular mechanisms underlying prohibitin 2 in platelet mitophagy and activation. Spandidos Publications  Molecular Medicine Reports  vol. 23, (5) 10.3892/mmr.2021.12023
Chen D, Zhang C, Chen J, Yang M, Afzal TA, An W, Maguire EM, He S, Luo J, Wang X, Zhao Y, Wu Q and Xiao Q (2021). miRNA-200c-3p promotes endothelial to mesenchymal transition and neointimal hyperplasia in artery bypass grafts. Journal of Pathology  vol. 253, (2) 209-224. 10.1002/path.5574

2020

Swiatlowska P, Sit B, Feng Z, Marhuenda E, Xanthis I, Zingaro S, Ward M, Zhou X, Xiao Q, Shanahan C, Jones G, Yu C-H and Iskratsch T (2020). Matrix stiffness and blood pressure together regulate vascular smooth muscle cell phenotype switching. 10.1101/2020.12.27.424498
Maguire EM and Xiao Q (2020). Noncoding RNAs in vascular smooth muscle cell function and neointimal hyperplasia. Febs Journal  vol. 287, (24) 5260-5283. 10.1111/febs.15357
He S, Yang F, Yang M, An W, Maguire EM, Chen Q, Xiao R, Wu W, Zhang L, Wang W and Xiao Q (2020). miR-214-3p-Sufu-GLI1 is a novel regulatory axis controlling inflammatory smooth muscle cell differentiation from stem cells and neointimal hyperplasia. Stem Cell Research and Therapy  vol. 11, (1) 10.1186/s13287-020-01989-w
Liu C, Niu K and Xiao Q (2020). Updated Perspectives On Vascular Cell Specification And Pluripotent Stem Cell-Derived Vascular Organoids For Studying Vasculopathies. Oxford University Press (Oup)  Cardiovascular Research  10.1093/cvr/cvaa313
Cai J, Deng J, Gu W, Ni Z, Liu Y, Kamra Y, Saxena A, Hu Y, Yuan H, Xiao Q, Lu Y and Xu Q (2020). Impact of Local Allo-Immunity and Recipient Cells in Transplant Arteriosclerosis. American Heart Association  Circulation Research  10.1161/CIRCRESAHA.119.316470
Pu X, Chan K, Yang W, Xiao Q, Zhang L, Moore AD, Liu C, Webb TR, Caulfield MJ, Samani NJ, Zhu J and Ye S (2020). Effect of a coronary-heart-disease-associated variant of ADAMTS7 on endothelial cell angiogenesis. Atherosclerosis  vol. 296, 11-17. 10.1016/j.atherosclerosis.2020.01.015

2019

Maguire EM, Pearce SWA, Xiao R, Oo AY and Xiao Q (2019). Matrix metalloproteinase in abdominal aortic aneurysm and aortic dissection. Pharmaceuticals  vol. 12, (3) 10.3390/ph12030118
Yang F, Chen Q, Yang M, Maguire EM, Yu X, He S, Xiao R, Wang CS, An W, Wu W, Zhou Y, Xiao Q and Zhang L (2019). Macrophage-derived MMP-8 determines smooth muscle cell differentiation from adventitia stem/progenitor cells and promotes neointima hyperplasia. Cardiovasc Res  10.1093/cvr/cvz044
Liu SS, Maguire EM, Bai YS, Huang L, Liu Y, Xu L, Fauzi I, Zhang SQ, Xiao Q and Ma NF (2019). A novel regulatory axis, CHD1L-MicroRNA 486-matrix metalloproteinase 2, controls spermatogonial stem cell properties. Molecular and Cellular Biology  vol. 39, (4) 10.1128/MCB.00357-18
Maguire EM, Pearce SWA and Xiao Q (2019). Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease. Vascular Pharmacology  vol. 112, 54-71. 10.1016/j.vph.2018.08.002

2018

Bonacina F, Coe D, Wang G, Longhi MP, Baragetti A, Moregola A, Garlaschelli K, Uboldi P, Pellegatta F, Grigore L, Da Dalt L, Annoni A, Gregori S, Xiao Q, Caruso D, Mitro N, Catapano AL, Marelli-Berg FM and Norata GD (2018). Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation. Nature Communications  vol. 9, (1) 10.1038/s41467-018-05322-1
Chen Q, Wang Q, Zhu J, Xiao Q and Zhang L (2018). Reactive oxygen species: key regulators in vascular health and diseases. British Journal of Pharmacology  vol. 175, (8) 1279-1292. 10.1111/bph.13828
Wen G, An W, Chen J, Maguire EM, Chen Q, Yang F, Pearce SWA, Kyriakides M, Zhang L, Ye S, Nourshargh S and Xiao Q (2018). Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis. J Am Heart Assoc  vol. 7, (4) 10.1161/JAHA.117.008187
Yang F, Chen Q, He S, Yang M, Maguire EM, An W, Afzal TA, Luong LA, Zhang L and Xiao Q (2018). miR-22 is a novel mediator of vascular smooth muscle cell phenotypic modulation and neointima formation. Circulation  vol. 137, (17) 1824-1841. 10.1161/CIRCULATIONAHA.117.027799
Ren M, Ng FL, Warren HR, Witkowska K, Baron M, Jia Z, Cabrera C, Zhang R, Mifsud B, Munroe PB, Xiao Q, Townsend-Nicholson A, Hobbs AJ, Ye S and Caulfield MJ (2018). The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle. Human Molecular Genetics  vol. 27, (1) 199-210. 10.1093/hmg/ddx375

2017

Zhang C, Chen D, Margaret Maguire E, He S, Chen J, An W, Yang M, Adeel Afzal T, Anh Luong L, Zhang L, Lei H, Wu Q and Xiao Q (2017). Cbx3 Inhibits Vascular Smooth Muscle Cell Proliferation, Migration and Neointima Formation. Oxford University Press (Oup)  Cardiovascular Research  10.1093/cvr/cvx236
Zhang L, Chen Q, An W, Yang F, Maguire EM, Chen D, Zhang C, Wen G, Yang M, Dai B, Luong LA, Zhu J, Xu Q and Xiao Q (2017). Novel Pathological Role of hnRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1) in Vascular Smooth Muscle Cell Function and Neointima Hyperplasia. American Heart Association/American Stroke Association  Arterioscler Thromb Vasc Biol  vol. 37, (11) 2182-2194. 10.1161/ATVBAHA.117.310020
AHLUWALIA A (2017). The anti-inflammatory actions of inorganic nitrate stabilise the atherosclerotic plaque. National Academy of Sciences  Proceedings of The National Academy of Sciences of Usa  10.1073/pnas.1613063114
Maguire EM, Xiao Q and Xu Q (2017). Differentiation and application of induced pluripotent stem cell?derived vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology  vol. 37, (11) 2026-2037. 10.1161/ATVBAHA.117.309196

2016

Afzal TA, Luong LA, Chen D, Zhang C, Yang F, Chen Q, An W, Wilkes E, Yashiro K, Cutillas PR, Zhang L and Xiao Q (2016). NCK Associated Protein 1 Modulated by miRNA-214 Determines Vascular Smooth Muscle Cell Migration, Proliferation, and Neointima Hyperplasia. Wiley  Journal of The American Heart Association  vol. 5, (12) e004629-e004629. 10.1161/JAHA.116.004629
Ren M, Ng F, Witkowska K, Baron M, Townsend-Nicholson A, Xiao Q, Hobbs A, Ye S and Caulfield MJ (2016). [OP.7C.08] BLOOD-PRESSURE ASSOCIATED VARIANTS IN NPR3 AFFECT HUMAN VASCULAR SMOOTH MUSCLE CELLS PROLIFERATION AND CALCIUM RESPONSE TO ANGIOTENSIN II. J Hypertens  vol. 34 Suppl 2, 10.1097/01.hjh.0000491573.57396.0f
Yang W, Ng FL, Chan K, Pu X, Poston RN, Ren M, An W, Zhang R, Wu J, Yan S, Situ H, He X, Chen Y, Tan X, Xiao Q, Tucker AT, Caulfield MJ and Ye S (2016). Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction., Editors: Humphries SE. Public Library of Science  Plos Genetics  vol. 12, (7) e1006127-e1006127. 10.1371/journal.pgen.1006127
Yang F, Chen Q, Wen G, Zhang C, Luong LA, Zhu J, Zhang L and Xiao Q (2016). Functional role of miRNA-34A in smooth muscle cell functions and neointima formation. Atherosclerosis  vol. 244, e3-e4. 10.1016/j.atherosclerosis.2015.10.060

2015

Chen Q, Yang F, Guo M, Wen G, Zhang C, Luong LA, Zhu J, Xiao Q and Zhang L (2015). miRNA-34a reduces neointima formation through inhibiting smooth muscle cell proliferation and migration. Journal of Molecular and Cellular Cardiology  vol. 89, 75-86. 10.1016/j.yjmcc.2015.10.017
Zeng L, Li Y, Yang J, Wang G, Margariti A, Xiao Q, Zampetaki A, Yin X, Mayr M, Mori K, Wang W, Hu Y and Xu Q (2015). XBP 1-deficiency abrogates neointimal lesion of injured vessels via cross talk with the PDGF signaling. Arteriosclerosis, Thrombosis, and Vascular Biology  vol. 35, (10) 2134-2144. 10.1161/ATVBAHA.115.305420
Ren M, Ng FL, Witkowska K, Baron M, Townsend-Nicholson A, Xiao Q, Hobbs A, Ye S and Caulfield M (2015). Blood-pressure associated variants in NPR3 affect human vascular smooth muscle cells proliferation and calcium response to angiotensin II. Journal of Human Hypertension  vol. 29, (10) 624-624.
Ren M, Ng FL, Witkowska K, Baron M, Townsend-Nicholson A, Xiao Q, Hobbs A, Ye S and Caulfield M (2015). Abstract P048: Blood-Pressure Associated Variants in Natriuretic Peptide Receptor C Affect Human Vascular Smooth Muscle Cells Proliferation and Calcium Flux in Response to Angiotensin II. Hypertension  vol. 66, (suppl_1) 10.1161/hyp.66.suppl_1.p048
Wen G, Zhang C, Chen Q, Luong LA, Mustafa A, Ye S and Xiao Q (2015). A novel role of matrix metalloproteinase-8 in macrophage differentiation and polarization. Journal of Biological Chemistry  vol. 290, (31) 19158-19172. 10.1074/jbc.M114.634022
Yu X, Zhang L, Wen G, Zhao H, Luong LA, Chen Q, Huang Y, Zhu J, Ye S, Xu Q, Wang W and Xiao Q (2015). Upregulated sirtuin 1 by miRNA-34a is required for smooth muscle cell differentiation from pluripotent stem cells. Cell Death and Differentiation  vol. 22, (7) 1170-1180. 10.1038/cdd.2014.206
Zhao H, Wen G, Huang Y, Yu X, Chen Q, Afzal TA, Luong LA, Zhu J, Shu Y, Zhang L and Xiao Q (2015). MicroRNA-22 Regulates Smooth Muscle Cell Differentiation From Stem Cells by Targeting Methyl CpG-Binding Protein 2. Arteriosclerosis Thrombosis and Vascular Biology  vol. 35, (4) 918-929. 10.1161/ATVBAHA.114.305212

2014

Yu X, Zhang L, Wen G, Zhao H, Luong LA, Chen Q, Huang Y, Zhu J, Ye S, Xu Q, Wang W and Xiao Q (2014). Upregulated sirtuin 1 by miRNA-34a is required for smooth muscle cell differentiation from pluripotent stem cells. Nature Publishing Group  Cell Death and Differentiation  10.1038/cdd.2014.206
Wen G, Chen Q, Le Anh Luong , Mustafa A, Shu Y and Xiao Q (2014). Matrix metalloproteinase-8 (MMP8) modulates M2 macrophage polarization and molecular mechanisms involved. Atherosclerosis  vol. 237, (2) 10.1016/j.atherosclerosis.2014.10.081
Zhao H, Wen G, Huang Y, Yu X, Chen Q, Afzal TA, Le Anh Luong , Zhu J, Shu Y, Zhang L and Xiao Q (2014). MicroRNA-22 regulates smooth muscle cell differentiation from stem cells by targeting methyl CpG binding protein 2. Atherosclerosis  vol. 237, (2) 10.1016/j.atherosclerosis.2014.10.080
Xiao Q, Zhang F, Grassia G, Hu Y, Zhang Z, Xing Q, Yin X, Maddaluno M, Drung B, Schmidt B, Maffia P, Ialenti A, Mayr M, Xu Q and Ye S (2014). Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation. Arterioscler Thromb Vasc Biol  vol. 34, (1) 90-98. 10.1161/ATVBAHA.113.301418

2013

Zeng L, Wang G, Ummarino D, Margariti A, Xu Q, Xiao Q, Wang W, Zhang Z, Yin X, Mayr M, Cockerill G, Li JY-S, Chien S, Hu Y and Xu Q (2013). Histone deacetylase 3 unconventional splicing mediates endothelial-to-mesenchymal transition through transforming growth factor β2. J Biol Chem  vol. 288, (44) 31853-31866. 10.1074/jbc.M113.463745
Luo Z, Wen G, Wang G, Pu X, Ye S, Xu Q, Wang W and Xiao Q (2013). MicroRNA-200C and -150 play an important role in endothelial cell differentiation and vasculogenesis by targeting transcription repressor ZEB1. Stem Cells  vol. 31, (9) 1749-1762. 10.1002/stem.1448
Zhao H, Huang Y, Yu X, Wen G, Wang W, Ye S and Xiao Q (2013). Abstract 004: Microrna-22 Regulates Smooth Muscle Cell Differentiation From Stem Cells By Targeting Methyl Cpg Binding Protein 2. Circulation Research  vol. 113, (suppl_1) 10.1161/res.113.suppl_1.a004
Chen Q, Jin M, Yang F, Zhu J, Xiao Q and Zhang L (2013). Matrix metalloproteinases: Inflammatory regulators of cell behaviors in vascular formation and remodeling. Mediators of Inflammation  vol. 2013, 10.1155/2013/928315
Fang C, Wen G, Zhang L, Lin L, Moore A, Wu S, Ye S and Xiao Q (2013). An important role of matrix metalloproteinase-8 in angiogenesis in vitro and in vivo. Cardiovasc Res  vol. 99, (1) 146-155. 10.1093/cvr/cvt060
Huang Y, Lin L, Yu X, Wen G, Pu X, Zhao H, Fang C, Zhu J, Ye S, Zhang L and Xiao Q (2013). Functional involvements of heterogeneous nuclear ribonucleoprotein A1 in smooth muscle differentiation from stem cells in vitro and in vivo. Stem Cells  vol. 31, (5) 906-917. 10.1002/stem.1324
Zeng L, Xiao Q, Chen M, Margariti A, Martin D, Ivetic A, Xu H, Mason J, Wang W, Cockerill G, Mori K, Yi-Shuan Li J, Chien S, Hu Y and Xu Q (2013). Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis. Circulation  vol. 127, (16) 1712-1722. 10.1161/CIRCULATIONAHA.112.001337
Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C, Patel A, Senver EC, Shaw-Hawkins S, Willeit J, Liu C, Zhu J, Tucker AT, Xu Q, Caulfield MJ and Ye S (2013). ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant. Am J Hum Genet  vol. 92, (3) 366-374. 10.1016/j.ajhg.2013.01.012
Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C, Patel A, Senver EC, Shaw-Hawkins S, Willeit J, Liu C, Zhu J, Tucker AT, Xu Q, Caulfield MJ and Ye S (2013). ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant. American Journal of Human Genetics  vol. 92, (3) 366-374. 10.1016/j.ajhg.2013.01.012
Margariti A, Li H, Chen T, Martin D, Vizcay-Barrena G, Alam S, Karamariti E, Xiao Q, Zampetaki A, Zhang Z, Wang W, Jiang Z, Gao C, Ma B, Chen YG, Cockerill G, Hu Y, Xu Q and Zeng L (2013). XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation. Journal of Biological Chemistry  vol. 288, (2) 859-872. 10.1074/jbc.M112.412783
Xiao Q, Zhang F, Lin L, Fang C, Wen G, Tsai T-N, Pu X, Sims D, Zhang Z, Yin X, Thomaszewski B, Schmidt B, Mayr M, Suzuki K, Xu Q and Ye S (2013). Functional role of matrix metalloproteinase-8 in stem/progenitor cell migration and their recruitment into atherosclerotic lesions. Circ Res  vol. 112, (1) 35-47. 10.1161/CIRCRESAHA.112.274019
Zheng X, Wu Y, Zhu L, Chen Q, Zhou Y, Yan H, Chen T, Xiao Q, Zhu J and Zhang L (2013). Angiotensin II promotes differentiation of mouse embryonic stem cells to smooth muscle cells through PI3-kinase signaling pathway and NF-κB. Differentiation  vol. 85, (1-2) 41-54. 10.1016/j.diff.2012.11.003
Zhou Y, Yan H, Guo M, Zhu J, Xiao Q and Zhang L (2013). Reactive Oxygen Species in Vascular Formation and Development. Oxidative Medicine and Cellular Longevity  vol. 2013, 10.1155/2013/374963
Chen Q, Jin M, Zhu J, Xiao Q and Zhang L (2013). Functions of Heterogeneous Nuclear Ribonucleoproteins in Stem Cell Potency and Differentiation. Biomed Research International  vol. 2013, 10.1155/2013/623978

2012

Huang Y, Lin L, Yu X, Pu X, Zhu J, Zhang L, Ye S and Xiao Q (2012). Functional Involvements of Heterogeneous Nuclear Ribonucleoprotein A1 in Smooth Muscle Differentiation from Stem Cells in vitro and in vivo. Circulation  vol. 126, (21)
Zhang L, Zheng X, Wu Y, Chen Q, Zhu J and Xiao Q (2012). Microrna-34a Regulates Smooth Muscle Cell Differentiation from Stem Cells by 'Targeting Sirtnin 1. Circulation  vol. 126, (21)
Luo Z, Wen G, Wang G, Pu X, Wang W, Ye S, Xu Q and Xiao Q (2012). Microrna-200c and-150 Play a Role in Human Embryonic Stem Cell Differentiation Into Endothelial Cells and Blood Vessel Formation by Targeting Transcription Repressor Zebi. Circulation  vol. 126, (21)
Xiao Q, Zhang F, Grassia G, Hu Y, Zhang Z, Xing Q, Yin X, Maddaluno M, Drung B, Schmidt B, Maffia P, Ialenti A, Mayr M, Xu Q and Ye S (2012). Matrix Metalloproteinase-8 Promotes Vascular Smooth Muscle Cell Proliferation and Neointima Formation. Circulation  vol. 126, (21)
Xiao Q, Zhang F, Lin L, Fang C, Wen G, Tsai T-N, Pu X, Sims D, Zhang Z, Thomaszewski B, Schmidt B, Mayr M, Suzuki K, Xu Q and Ye S (2012). A Functional Role of Matrix Metalloproteinase-8 in Stem/progenitor Cell Migration and Their Recruitment Into Atherosclerotic Lesions. Circulation  vol. 126, (21)
Motterle A, Pu X, Wood H, Xiao Q, Gor S, Ng FL, Chan K, Cross F, Shohreh B, Poston RN, Tucker AT, Caulfield MJ and Ye S (2012). Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells. Hum Mol Genet  vol. 21, (18) 4021-4029. 10.1093/hmg/dds224
Tsai TN, Kirton JP, Campagnolo P, Zhang L, Xiao Q, Zhang Z, Wang W, Hu Y and Xu Q (2012). Contribution of stem cells to neointimal formation of decellularized vessel grafts in a novel mouse model. American Journal of Pathology  vol. 181, (1) 362-373. 10.1016/j.ajpath.2012.03.021
Xiao Q, Pepe AE, Wang G, Luo Z, Zhang L, Zeng L, Zhang Z, Hu Y, Ye S and Xu Q (2012). Nrf3-Pla2g7 interaction plays an essential role in smooth muscle differentiation from stem cells. Arterioscler Thromb Vasc Biol  vol. 32, (3) 730-744. 10.1161/ATVBAHA.111.243188
Xiao Q, Pepe AE, Wang G, Luo Z, Zhang L, Zeng L, Zhang Z, Hu Y, Ye S and Xu Q (2012). Nrf3-Pla2g7 interaction plays an essential role in smooth muscle differentiation from stem cells. Arteriosclerosis, Thrombosis, and Vascular Biology  vol. 32, (3) 730-744. 10.1161/ATVBAHA.111.243188
Liang Q-L, Liang X-P, Wang Y-M, Xie Y-Y, Zhang R-L, Chen X, Gao R, Cheng Y-J, Wu J, Xu Q-B, Xiao Q-Z, Li X, Lv S-F, Fan X-M, Zhang H-Y, Zhang Q-L and Luo G-A (2012). Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on system to system mode. Journal of Translational Medicine  vol. 10, 10.1186/1479-5876-10-26
Knoflach M, Kiechl S, Mantovani A, Cuccovillo I, Bottazzi B, Xu Q, Xiao Q, Gasperi A, Mayr A, Kehrer M, Willeit J and Wick G (2012). Pentraxin-3 as a Marker of Advanced Atherosclerosis Results from the Bruneck, ARMY and ARFY Studies. Plos One  vol. 7, (2) 10.1371/journal.pone.0031474
Motterle A, Xiao Q, Kiechl S, Pender SLF, Morris GE, Willeit J, Caulfield MJ and Ye S (2012). Influence of matrix metalloproteinase-12 on fibrinogen level. Atherosclerosis  vol. 220, (2) 351-354. 10.1016/j.atherosclerosis.2011.11.003
Wang G, Xiao Q, Luo Z, Ye S and Xu Q (2012). Functional impact of heterogeneous nuclear ribonucleoprotein A2/B1 in smooth muscle differentiation from stem cells and embryonic arteriogenesis. J Biol Chem.  vol. 287, (4) 2896-2906. 10.1074/jbc.M111.297028
Wang G, Xiao Q, Luo Z, Ye S and Xu Q (2012). Functional impact of heterogeneous nuclear ribonucleoprotein A2/B1 in smooth muscle differentiation from stem cells and embryonic arteriogenesis. J Biol Chem  vol. 287, (4) 2896-2906. 10.1074/jbc.M111.297028
Sims D and Xiao Q (2012). Smooth muscle cell differentiation from embryonic stem cells: Role of HDAC7 and PDGF-BB. Stem Cells and Cancer Stem Cells, Volume 4: Therapeutic Applications in Disease and Injury  10.1007/978-94-007-2828-8_7

2011

Kiechl S, Paré G, Barbalic M, Qi L, Dupuis J, Dehghan A, Bis JC, Laxton RC, Xiao Q, Bonora E, Willeit J, Xu Q, Witteman JCM, Chasman D, Tracy RP, Ballantyne CM, Ridker PM, Benjamin EJ and Ye S (2011). Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis. Circ Cardiovasc Genet  vol. 4, (6) 681-686. 10.1161/CIRCGENETICS.111.960682
Zhou B, Margariti A, Zeng L, Habi O, Xiao Q, Martin D, Wang G, Hu Y, Wang X and Xu Q (2011). Splicing of histone deacetylase 7 modulates smooth muscle cell proliferation and neointima formation through nuclear β-catenin translocation. Arterioscler Thromb Vasc Biol  vol. 31, (11) 2676-2684. 10.1161/ATVBAHA.111.230888
Luo Z, Xiao Q, Wang W and Xu Q (2011). DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS TOWARDS THE ENDOTHELIAL LINEAGE INVOLVES MICRORNAS. Heart  vol. 97, (20) 4-4. 10.1136/heartjnl-2011-300920b.6
Wang G, Xiao Q and Xu Q (2011). STEM CELL DIFFERENTIATION TO SMOOTH MUSCLE CELLS IS REGULATED BY HNRNP A2/B1. Heart  vol. 97, (20) 3-4. 10.1136/heartjnl-2011-300920b.4
Xiao Q, Wang G, Yin X, Luo Z, Margariti A, Zeng L, Mayr M, Ye S and Xu Q (2011). Chromobox protein homolog 3 is essential for stem cell differentiation to smooth muscles in vitro and in embryonic arteriogenesis. Arterioscler Thromb Vasc Biol  vol. 31, (8) 1842-1852. 10.1161/ATVBAHA.111.230110
Luo ZL, Wang G, Wang W, Xiao QZ and Xu QB (2011). Signalling pathways that regulate endothelial differentiation from stem cells. Front Biosci-Landmrk  vol. 16, 472-485. 10.2741/3699
Kane NM, Xiao Q, Baker AH, Luo Z, Xu Q and Emanueli C (2011). Pluripotent Stem Cell Differentiation into Vascular Cells: A Novel Technology with Promises for Vascular Re(Generation). Pharmacol Ther.  vol. 129, (1) 29-49. 10.1016/j.pharmthera.2010.10.004
Xiao Q and Ye S (2011). The genetics of epigenetics: is there a link with cardiovascular disease. Heart  vol. 97, (2) 96-97. 10.1136/hrt.2010.214833

2010

Zhang L, Jin M, Margariti A, Wang G, Luo Z, Zampetaki A, Zeng L, Ye S, Zhu J and Xiao Q (2010). Sp1-dependent activation of HDAC7 is required for platelet-derived growth factor-BB-induced smooth muscle cell differentiation from stem cells. J Biol Chem  vol. 285, (49) 38463-38472. 10.1074/jbc.M110.153999
Kiechl S, Laxton RC, Xiao Q, Hernesniemi JA, Raitakari OT, Kähönen M, Mayosi BM, Jula A, Moilanen L, Willeit J, Watkins H, Samani NJ, Lehtimäki TJ, Keavney B, Xu Q and Ye S (2010). Coronary artery disease-related genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis. Arterioscler Thromb Vasc Biol  vol. 30, (12) 2678-2683. 10.1161/ATVBAHA.110.213785
Zeng L, Xiao Q, Li H, Margariti A, Hu Y and Xu Q (2010). Xbp1 Splicing is Crucial in Endothelial Cell Proliferation. Circulation  vol. 122, (21)
Xiao Q, Pepe AE and Xu Q (2010). Pla2g7 is Crucial in Stem Cell Differentiation into Smooth Muscle Cells and Involves in Atherosclerosis. Circulation  vol. 122, (21)
Margariti A, Li H, Martin D, Xiao Q, Zampetaki A, Hu Y, Xu Q and Zeng L (2010). X-Box Binding Protein 1 Splicing Triggers an Autophagic Response-Mediated Survival in Endothelial Cells. Circulation  vol. 122, (21)
Dotsenko O, Xiao Q, Xu Q and Jahangiri M (2010). Bone Marrow Resident and Circulating Progenitor Cells in Patients Undergoing Cardiac Surgery. Annals of Thoracic Surgery  vol. 90, (6) 1944-1951. 10.1016/j.athoracsur.2010.08.033
Zhang L, Jin M, Margariti A, Wang G, Luo Z, Zampetaki A, Zeng L, Ye S, Zhu J and Xiao Q (2010). Sp1-dependent activation of HDAC7 is required for PDGF-BB-induced smooth muscle cell differentiation from stem cells. The Journal of Biological Chemistry  vol. 285, 38463-38472. 10.1074/jbc.M110.153999
xiao Q, Wang G, Luo Z and Xu Q (2010). The mechanism of stem cell differentiation into smooth muscle cells. Thromb Haemost  vol. 104, (3) 440-448. 10.1160/TH09-11-0794
Xiao Q, Wang G, Bai X, Yin X, Luo Z, Mayr M, Ye S and Xu Q (2010). BAS/BSCR30 Crucial roles of Cbx3 identified by nuclear proteomics in smooth muscle differentiation from stem cells and vascular injury-induced neointima formation. Heart  vol. 96, (17) 10.1136/hrt.2010.205781.41
Zeng L, Xiao Q, Li H, Margariti A, Hu Y and Xu Q (2010). BAS/BSCR43 X-box binding protein 1 splicing is crucial in endothelial cell proliferation. Heart  vol. 96, (17) 10.1136/hrt.2010.205781.54
Margariti A, Zampetaki A, Xiao Q, Zou B, Karamariti E, Martin D, Yin X, Mayr M, Li H and Zhang Z (2010). Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin. Circ Res.  vol. 106, (7) 1202-1211. 10.1161/CIRCRESAHA.109.213165
Pepe AE, Xiao Q, Zampetaki A, Zhang Z, Kobayashi A, Hu Y and Xu Q (2010). Crucial role of nrf3 in smooth muscle cell differentiation from stem cells. Circ Res.  vol. 106, (5) 870-879. 10.1161/CIRCRESAHA.109.211417
Ye S, Willeit J, Xiao Q, Motterle A, Laxton RC, Oberhollenzer F, Kiechl S and Xu Q (2010). Single nucleotide polymorphism on chromosome 9p21 and endothelial progenitor cells in a general population cohort. Atherosclerosis  vol. 208, (2) 451-455. 10.1016/j.atherosclerosis.2009.08.006
(2010). A Role of Matrix Metalloproteinase-8 in Atherosclerosis: Correction. Circulation Research  vol. 106, (1) 10.1161/res.0b013e3181cdee32
Zampetaki A, Zeng L, Margariti A, Xiao Q, Li H, Zhang Z, Pepe AE, Wang G, Habi O, deFalco E, Cockerill G, Mason JC, Hu Y and Xu Q (2010). Histone deacetylase 3 is critical in endothelial survival and atherosclerosis development in response to disturbed flow. Circulation  vol. 121, (1) 132-142. 10.1161/CIRCULATIONAHA.109.890491

2009

Pepe AE, Xiao Q, Zampetaki A and Xu Q (2009). NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 3 MEDIATES STEM CELL DIFFERENTIATION INTO SMOOTH MUSCLE CELLS THROUGH INCREASED REACTIVE OXYGEN SPECIES GENERATION AND PLASMA PHOSPHOLIPASE A2 PRODUCTION. Heart  vol. 95, (22) 10.1136/hrt.2009.178137x
Xiao Q, Luo Z, Pepe A, Margariti A, Zeng L and Xu Q (2009). NADPH OXIDASE PRODUCED HYDROGEN PEROXIDE-MEDIATED SMOOTH MUSCLE CELL DIFFERENTIATION FROM STEM CELL. Heart  vol. 95, (22) 10.1136/hrt.2009.181669l
Mayr U, Pula G, Evans C, Prokopi M, Yin X, Xiao Q, Hill J, Xu Q and Mayr M (2009). PROTEOMICS IDENTIFIES THYMIDINE PHOSPHORYLASE AS A KEY REGULATOR OF THE ANGIOGENIC POTENTIAL OF COLONY FORMING UNITS AND ENDOTHELIAL PROGENITOR CELL CULTURES. Heart  vol. 95, (22) 10.1136/hrt.2009.178129g
Laxton RC, Hu Y, Duchene J, Zhang F, Zhang Z, Leung K-Y, Xiao Q, Scotland RS, Hodgkinson CP, Smith K, Willeit J, López-Otín C, Simpson IA, Kiechl S, Ahluwalia A, Xu Q and Ye S (2009). A role of matrix metalloproteinase-8 in atherosclerosis. Circ Res  vol. 105, (9) 921-929. 10.1161/CIRCRESAHA.109.200279
Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, Boulanger CM, Westwood N, Urbich C and Willeit J (2009). Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Blood  vol. 114, (3) 723-732. 10.1136/hrt.2009.178137y
Dotsenko O, Xiao Q, Xu Q and Jahangiri M (2009). SEVERITY OF CORONARY ATHEROSCLEROSIS AND CARDIOPULMONARY BYPASS AFFECT STEM CELL TRAFFICKING FOLLOWING CARDIAC SURGERY. Atherosclerosis Supplements  vol. 10, (2)
Dotsenko O, Xiao Q, Xu Q and Jahangiri M (2009). Abstract: P224 SEVERITY OF CORONARY ATHEROSCLEROSIS AND CARDIOPULMONARY BYPASS AFFECT STEM CELL TRAFFICKING FOLLOWING CARDIAC SURGERY. Atherosclerosis Plus  vol. 10, (2) 10.1016/s1567-5688(09)70531-8
Zeng L, Zampetaki A, Margariti A, Pepe AE, Alam S, Martin D, Xiao Q, Wang W, Jin ZG and Cockerill G (2009). Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow. Proc Natl Acad Sci U S a.  vol. 106, (20) 8326-8331.
Xiao Q and Xu Q (2009). Caspase-8, a double-edged sword for EPC functioning. Arterioscler Thromb Vasc Biol.  vol. 29, (4) 444-446. 10.1161/ATVBAHA.108.183087
Xiao Q, Luo Z, Pepe AE, Margariti A, Zeng L and Xu Q (2009). Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H2O2. Am J Physiol Cell Physiol.  vol. 296, (4) C711-C723. 10.1152/ajpcell.00442.2008
Margariti A, Xiao Q, Zampetaki A, Zhang Z, Li H, Martin D, Hu Y, Zeng L and Xu Q (2009). Splicing of HDAC7 modulates the SRF-myocardin complex during stem-cell differentiation towards smooth muscle cells. J Cell Sci.  vol. 122, (4) 460-470. 10.1242/​jcs.034850
Pula G, Mayr U, Evans C, Prokopi M, Vara DS, Yin X, Astroulakis Z, Xiao Q, Hill J and Xu Q (2009). Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures. Circ Res.  vol. 104, (1) 32-40. 10.1161/CIRCRESAHA.108.182261
Xiao Q, Savvidou MD and Nicolaides KH (2009). Endothelial progenitor cells and pregnancy REPLY. American Journal of Obstetrics and Gynecology  vol. 200, (1) E19-E20. 10.1016/j.ajog.2008.06.042
Dotsenko O, Xiao Q, Xu Q and Jahangiri M (2009). Egress of Functionally Competent Progenitor Cells Over-Expressing Cxcr4 from the Bone Marrow Following Cardiac Surgery with the Use of Cardiopulmonary Bypass. Artery Research  vol. 3, (4) 10.1016/j.artres.2009.10.053

2008

Xiao Q, Ye S, Oberhollenzer F, Mayr A, Jahangiri M, Willeit J, Kiechl S and Xu Q (2008). SDF1 gene variation is associated with circulating SDF1alpha level and endothelial progenitor cell number: the Bruneck Study. Plos One  vol. 3, (12)
Xiao Q, Zhang L, Luo Z, Pepe A, Margariti A, Zeng L and Xu Q (2008). Nox4 is Crucial for Stem Cell Differentiation into Smooth Muscle Cells. Circulation  vol. 118, (18) S411-S411.
Pula G, Mayr U, Evans C, Prokopi M, Xiao Q, Hill J, Xu Q and Mayr M (2008). Proteomics Identifies Thymidine Phosphorylase as a Key Regulator of the Angiogenic Potential of Endothelial Progenitor Cells. Circulation  vol. 118, (18) S412-S412.
Foteinos G, Hu Y, Xiao Q, Metzler B and Xu Q (2008). Rapid endothelial turnover in atherosclerosis-prone areas coincides with stem cell repair in apolipoprotein E-deficient mice. Circulation  vol. 117, (14) 1856-1863. 10.1161/​CIRCULATIONAHA.107.746008
Savvidou MD, Xiao Q, Kaihura C, Anderson JM and Nicolaides KH (2008). Maternal circulating endothelial progenitor cells in normal singleton and twin pregnancy. Am J Obstet Gynecol.  vol. 198, (4) 414.e1-414.e5. 10.1016/j.ajog.2007.10.800
Xiao Q, Ye S, Oberhollenzer F, Mayr A, Jahangiri M, Willeit J, Kiechl S and Xu Q (2008). SDF1 gene variation is associated with circulating SDF1alpha level and endothelial progenitor cell number: the Bruneck Study. Plos One  vol. 3, (12) 10.1371/journal.pone.0004061

2007

Adams B, Xiao Q and Xu Q (2007). Vascular progenitor cells and atherosclerosis. Future Cardiology  vol. 3, (6) 635-645. 10.2217/14796678.3.6.635
Qi XW, Liu HF, Xue YZ, Kong XQ, Xu QB and Xiao QZ (2007). Changes of endothelial progenitor cells and vascular endothelial growth factor in patients with coronary artery disease. Journal of Clinical Rehabilitative Tissue Engineering Research  vol. 11, (42) 8439-8443.
Margariti A, Xiao Q, Zampetaki A, Hu Y, Zeng L and Xu Q (2007). Abstract 433: HDAC7 is Essential for Stem Cell Differentiation into Smooth Muscle Cells. Circulation  vol. 116, (suppl_16) 10.1161/circ.116.suppl_16.ii_71-c
Xiao Q, Kiechl S, Patel S, Oberhollenzer F, Weger S, Mayr A, Metzler B, Reindl M, Hu Y, Willeit J and Xu Q (2007). Endothelial Progenitor Cells, Cardiovascular Risk Factors, Cytokine Levels and Atherosclerosis - Results from a Large Population-Based Study. Plos One  vol. 2, (10) 10.1371/journal.pone.0000975
Sidibe A, Yin X, Tarelli E, Xiao Q, Zampetaki A, Xu Q and Mayr M (2007). Integrated membrane protein analysis of mature and embryonic stem cell-derived smooth muscle cells using a novel combination of CyDye/biotin labeling. Mol Cell Proteomics  vol. 6, (10) 1788-1797. 10.1074/mcp.M600433-MCP200
Adams B, Xiao Q and Xu Q (2007). Stem cell therapy for vascular disease. Trends in Cardiovascular Medicine  vol. 17, (7) 246-251. 10.1016/j.tcm.2007.08.005
Zampetaki A, Zeng L, Xiao Q, Margariti A, Hu Y and Xu Q (2007). Lacking cytokine production in ES cells and ES-cell-derived vascular cells stimulated by TNF-alpha is rescued by HDAC inhibitor trichostatin A. American Journal of Physiology-Cell Physiology  vol. 293, (4) C1226-C1238. 10.1152/ajpcell.00152.2007
Roberts N, Xiao Q, Weir G, Xu Q and Jahangiri M (2007). Endothelial Progenitor Cells are Mobilized After Cardiac Surgery. Annals of Thoracic Surgery  vol. 83, (2) 598-605. 10.1016/j.athoracsur.2006.09.087
Xiao Q, Zeng L, Zhang Z, Hu Y and Xu Q (2007). Stem cell-derived Sca-1+ progenitors differentiate into smooth muscle cells, which is mediated by collagen IV-integrin α1/ β1v and PDGF receptor pathways. American Journal of Physiology - Cell Physiology  vol. 292, (1) 10.1152/ajpcell.00341.2006

2006

Yin XK, Mayr M, Xiao QZ, Wang W and Xu QB (2006). Proteomic analysis reveals higher demand for antioxidant protection in embryonic stem cell-derived smooth muscle cells. Proteomics  vol. 6, (24) 6437-6446. 10.1002/pmic.200600351
Xiao Q, Zeng L, Zhang Z, Margariti A, Ali ZA, Channon KM, Xu Q and Hu Y (2006). Sca-1+ progenitors derived from embryonic stem cells differentiate into endothelial cells capable of vascular repair after arterial injury. Arteriosclerosis, Thrombosis, and Vascular Biology  vol. 26, (10) 2244-2251. 10.1161/01.ATV.0000240251.50215.50
Zeng L, Xiao Q, Margariti A, Zhang Z, Zampetaki A, Patel S, Capogrossi MC, Hu Y and Xu Q (2006). HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells. Journal of Cell Biology  vol. 174, (7) 1059-1069. 10.1083/jcb.200605113
Yin X, Xiao Q, Mayr U, Mayr M and Xu Q (2006). Proteomic analysis of embryonic stem cell-derived smooth muscle cells. Vascular Pharmacology  vol. 45, (3) 10.1016/j.vph.2006.08.203
Zeng L, Xiao Q, Margariti A and Xu Q (2006). Shear stress-induced stem cell differentiation toward endothelial cells is regulated by HDAC-P53-P21 pathways. Vascular Pharmacology  vol. 45, (3) 10.1016/j.vph.2006.08.138
Zampetaki A, Xiao Q, Zeng L and Xu Q (2006). TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications. Vascular Pharmacology  vol. 45, (3) 10.1016/j.vph.2006.08.079
Zampetaki A, Xiao Q, Zeng L, Hu Y and Xu Q (2006). TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications. Biochemical and Biophysical Research Communications  vol. 347, (1) 89-99. 10.1016/j.bbrc.2006.06.055

2005

XIAO Q, Mandal K, Schett G, Mayr M, Wick G, Oberhollenzer F, Willeit J, Kiechl S and XU Q (2005). Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study. Lippincott Williams & Wilkins  Stroke  vol. 36, (12) 2571-2576. 10.1161/01.STR.0000189632.98944.ab
Dong XX, Liu JB, Dong YX, He HH, Dong WH, Liang ZP and Xiao QZ (2005). Chinese herbs for inducing differentiation of mesenchymal stem cells in rats. Chinese Journal of Clinical Rehabilitation  vol. 9, (9) 210-212.
WANG W, Yin XK, Xu QB, Wait R, Mayr U, Mayr M, Xiao QZ and Tarelli E (2005). Proteomic dataset of Sca-1+ progenitor cells. Proteomics  vol. 5, (17) 4533-4545. 10.1002/pmic.200402044
Xiao QZ, Su DH, Jiang JH and Zhong NS (2005). Distribution and drug-resistance of 3 500 gram-negative bacteria in Guangzhou. Di 1 Jun Yi Da Xue Xue Bao = Academic Journal of The First Medical College of Pla  vol. 25, (2) 132-138.

Grants

Grants of specific relevance to Predictive in vitro Models
Endothelial repair by CD34+ stem/progenitor cells in atherosclerosis
Xiao Q
£304,530 British Heart Foundation (01-05-2021 - 30-04-2024)


Long non-coding RNAs, the novel players in vascular stem cell differentiation and angioplasty restenosis
Xiao Q
£12,000 British Heart Foundation (01-10-2015 - 30-09-2019)
Summary
A novel role of Cezanne in vascular smooth muscle cell proliferation and neointima hyperplasia
Xiao Q
£231,758 British Heart Foundation (20-09-2016 - 19-09-2019)
Neotrophil elastase (NE): A new player in atherosclerosis
Xiao Q
£84,000 Medical Research Council (01-10-2015 - 30-09-2018)
Summary