Prof Yi Sui
Professor of Fluid Mechanics
School of Engineering and Materials Science
Queen Mary University of London
Queen Mary University of London
Research
computational modelling of cell dynamics in flows, microfluidics cell sorting and characterisation, real-time AI algorithms, in-vitro models for drug delivery
Interests
I am interested in sorting cells from patient blood that can be used to build complex in-vitro models.I have expertise in computational modelling of flow and mass transport, and AI-image based ultrahigh-throughput mechanical characterisation and label-free cell sorting. I am interested in using these tools to understand and develop microfluidics-based in-vitro models such as organ-chips.
Publications of specific relevance to Predictive in vitro Models
2026
Fractal-shaped droplet microfluidics for highly scalable cell mechanoporationSung M, Jing D, Joo B, Im S, Kim Y-J, Sui Y, Chung AJ
Lab On a Chip, Royal Society of Chemistry (Rsc) vol. 26 (1), 10-17.
01-01-2026
Real-time high-throughput characterisation of the surface elasticity of suspended cellsGuo Z, Sui Y, Wang W
Lab On a Chip, Royal Society of Chemistry (Rsc)
01-01-2026
2025
Transient flow-induced deformation of cancer cells in microchannels: a general computational model and experimentsLu R, Li J, Guo Z, Wang Z, Feng JJ, Sui Y
Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 24 (2), 489-506.
02-02-2025
2024
Droplets can enhance microcapsule deformation in channel flowJing D, Lu R, Farutin A, Guo Z, Wang F, Wang W, Misbah C, Sui Y
Communications Physics, Springer Nature vol. 7 (1)
20-09-2024
A computational study of cell membrane damage and intracellular delivery in a cross-slot microchannelLu R, Yu P, Sui Y
Soft Matter, Royal Society of Chemistry (Rsc) vol. 20 (20), 4057-4071.
01-01-2024
2023
Core–Shell-Structured Electrorheological Fluid with a Polarizability-Tunable Nanocarbon Shell for Enhanced Stimuli-Responsive ActivityChen S, Cheng Y, Zhao Z, Zhang K, Hao T, Sui Y, Wang W, Zhao J et al.
Acs Applied Materials & Interfaces, American Chemical Society (Acs) vol. 15 (29), 35741-35749.
14-07-2023
Transient deformation of a viscoelastic capsule in a cross-slot microchannel: effects of inertia and membrane viscosityLu RX, Guo ZY, Yu P, Sui Y
Journal of Fluid Mechanics, Cambridge University Press (Cup) vol. 962
03-05-2023
A method for real-time mechanical characterisation of microcapsulesGuo Z, Lin T, Jing D, Wang W, Sui Y
Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 22 (4), 1209-1220.
24-03-2023
A computational model for the transit of a cancer cell through a constricted microchannelWang Z, Lu R, Wang W, Tian FB, Feng JJ, Sui Y
Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 22 (4), 1129-1143.
28-02-2023
2022
Acoustically accelerated neural differentiation of human embryonic stem cellsSun C, Dong Y, Wei J, Cai M, Liang D, Fu Y, Zhou Y, Sui Y et al.
Acta Biomaterialia, Elsevier vol. 151, 333-345.
29-07-2022
Characterising Mechanical Properties of Flowing Microcapsules Using a Deep Convolutional Neural NetworkLin T, Wang Z, Lu RX, Wang W, Sui Y
Advances in Applied Mathematics and Mechanics, Global Science Press vol. 14 (1), 79-100.
01-06-2022
2021
Path selection of a train of spherical capsules in a branched microchannelLu RX, Wang Z, Salsac A-V, Barthès-Biesel D, Wang W, Sui Y
Journal of Fluid Mechanics, Cambridge University Press (Cup) vol. 923
22-07-2021
A high-throughput method to characterize membrane viscosity of flowing microcapsulesLin T, Wang Z, Lu R, Wang W, Sui Y
Physics of Fluids, Aip Publishing vol. 33 (1)
01-01-2021
A neural network-based algorithm for high-throughput characterisation of viscoelastic properties of flowing microcapsulesLin T, Wang Z, Wang W, Sui Y
Soft Matter, Royal Society of Chemistry (Rsc) vol. 17 (15), 4027-4039.
01-01-2021
2020
An immersed boundary-lattice Boltzmann method for fluid-structure interaction problems involving viscoelastic fluids and complex geometriesMa J, Wang Z, Young J, Lai JCS, Sui Y, Tian F-B
Journal of Computational Physics, Elsevier vol. 415
01-08-2020
2019
Path Selection of a Spherical Capsule in a Branched ChannelWang Z, Sui Y, Wang W, Barthѐs-Biesel D, Salsac A-V
Molecular & Cellular Biomechanics, Tech Science Press vol. 16 (S2), 42-43.
01-01-2019
2018
A fate-alternating transitional regime in contracting liquid filamentsWang F, Contò FP, Naz N, Castrejón-Pita JR, Castrejón-Pita AA, Bailey CG, Wang W, Feng JJ et al.
Journal of Fluid Mechanics, Cambridge University Press (Cup) vol. 860, 640-653.
10-12-2018
Path selection of a spherical capsule in a microfluidic branched channel: Towards the design of an enrichment deviceWang Z, Sui Y, Salsac AV, Barthès-Biesel D, Wang W
Journal of Fluid Mechanics vol. 849, 136-162.
18-06-2018
2017
Benchmark numerical solutions for two-dimensional fluid–structure interaction involving large displacements with the deforming-spatial-domain/stabilized space–time and immersed boundary–lattice Boltzmann methodsXu Y-Q, Jiang Y-Q, Wu J, Sui Y, Tian F-B
Proceedings of The Institution of Mechanical Engineers Part C Journal of Mechanical Engineering Science, Sage Publications vol. 232 (14), 2500-2514.
01-08-2017
2016
Motion of a spherical capsule in branched tube flow with finite inertiaWang Z, Sui Y, Salsac A-V, Barthès-Biesel D, Wang W
Journal of Fluid Mechanics, Cambridge University Press (Cup) vol. 806, 603-626.
13-10-2016
Swimming performance and vorticity structures of a mother-calf pair of fishTian F-B, Wang W, Wu J, Sui Y
Computers & Fluids vol. 124, 1-11.
01-01-2016
Grants of specific relevance to Predictive in vitro Models
Newton International Fellowship alumni: Dynamics of a microcapsule (Dalei Jing)Yi Sui
£6,000 Royal Society
31-03-2026 - 30-03-2027
Fluid Dynamics of Microfluidic Cell Mechanoporation for Intracellular Gene DeliveryYi Sui
£12,000 Royal Society
01-08-2025 - 31-07-2027
EPSRC Centre for Doctoral Training in Next Generation Organ-on-a-Chip Technology (COaCT)Hazel Screen, Martin Knight, Thomas Iskratsch, Caroline Roney, Yi Sui, David Lee, Julia Shelton, Zion Tse, John Connelly, Adrian Biddle and Lucy Norling
£7,066,811 Engineering and Physical Sciences Research Council
Grant Summary
01-07-2024 - 30-09-2032