Publications

 

The following journal papers published by the members of the CPM, specifically relate to the development and/or use of predictive in vitro models.

  • Titanium Dioxide/Graphene Oxide Composite Coatings for 316 Stainless Steel Dental Implants.
    Al-Noaman AS and Rawlinson SF
    European Journal of Prosthodontics and Restorative Dentistry vol. 31 (4), 358-372.  
    30-11-2023
  • Controlled electroactive release from solid-state conductive elastomer electrodes
    Chapman CAR, Fernandez-Patel S, Jahan N, Cuttaz EA, Novikov A, Goding JA and Green RA
    Materials Today Bio, Elsevier vol. 23 
    28-11-2023
  • The Annexin-A1 mimetic RTP-026 promotes acute cardioprotection through modulation of immune cell activation
    Chen J, Oggero S, Cecconello C, Dalli J, Hayat H, Hjiej Andaloussi A, Sanni S, Jonassen TE and Perretti M
    Pharmacological Research, Elsevier vol. 198 
    21-11-2023
  • Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion
    Aguirre GA, Goulart MR, Bank BPT, Dalli J and Kocher HM
    Frontiers in Immunology, Frontiers vol. 14 
    16-11-2023
  • A Novel Primary Cilium‐Mediated Mechanism Through which Osteocytes Regulate Metastatic Behavior of Both Breast and Prostate Cancer Cells
    Verbruggen SW, Nolan J, Duffy MP, Pearce OMT, Jacobs CR and Knight MM
    Advanced Science, Wiley vol. 11 (2), 2305842-2305842.  
    15-11-2023
  • Mucosal Immunity to Gut Fungi in Health and Inflammatory Bowel Disease
    Carlson SL, Mathew L, Savage M, Kok K, Lindsay JO, Munro CA and McCarthy NE
    Journal of Fungi, Mdpi vol. 9 (11) 
    14-11-2023
  • CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells
    Samain R, Maiques O, Monger J, Lam H, Candido J, George S, Ferrari N, KohIhammer L, Lunetto S, Varela A, Orgaz JL, Vilardell F, Olsina JJ, Matias-Guiu X, Sarker D, Biddle A, Balkwill FR, Eyles J, Wilkinson RW, Kocher HM, Calvo F, Wells CM and Sanz-Moreno V
    Science Advances, American Association For The Advancement of Science (Aaas) vol. 9 (42) 
    18-10-2023
  • Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment
    Thompson CL, Hopkins T, Bevan C, Screen HRC, Wright KT and Knight MM
    Biomedical Materials, Iop Publishing vol. 18 (6) 
    10-10-2023
  • P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes
    Beltran-Lobo P, Hughes MM, Troakes C, Croft CL, Rupawala H, Jutzi D, Ruepp M-D, Jimenez-Sanchez M, Perkinton MS, Kassiou M, Golde TE, Hanger DP, Verkhratsky A, Perez-Nievas BG and Noble W
    Brain Behavior and Immunity, Elsevier vol. 114, 414-429.  
    15-09-2023
  • Cx43 regulates mechanotransduction mechanisms in human preterm amniotic membrane defects
    Costa E, Thrasivoulou C, Becker DL, Deprest JA, David AL and Chowdhury TT
    Prenatal Diagnosis, Wiley 
    30-08-2023
  • The Future of Precision Oncology
    Rulten SL, Grose RP, Gatz SA, Jones JL and Cameron AJM
    International Journal of Molecular Sciences, Mdpi vol. 24 (16) 
    09-08-2023
  • Nonaffine Mechanics of Entangled Networks Inspired by Intermediate Filaments
    Pensalfini M, Golde T, Trepat X and Arroyo M
    Physical Review Letters, American Physical Society (Aps) vol. 131 (5) 
    04-08-2023
  • Polyether ether ketone coated with nanohydroxyapatite/graphene oxide composite promotes bioactivity and antibacterial activity at the surface of the material
    Al‐Noaman A and Rawlinson SCF
    European Journal of Oral Sciences, Wiley vol. 131 (5-6) 
    02-08-2023
  • Core–Shell-Structured Electrorheological Fluid with a Polarizability-Tunable Nanocarbon Shell for Enhanced Stimuli-Responsive Activity
    Chen S, Cheng Y, Zhao Z, Zhang K, Hao T, Sui Y, Wang W, Zhao J and Li Y
    Acs Applied Materials & Interfaces, American Chemical Society (Acs) vol. 15 (29), 35741-35749.  
    14-07-2023
  • O06 Exploring host–microbiome–immune interactions using singular and multispecies inoculations in optimized 3D skin models
    McPolin-Hall E, Stephen A, Pardieu C, Allaker R, Philpott M, Bhogal R, Pople J and Hannen R
    British Journal of Dermatology, Oxford University Press (Oup) vol. 189 (1), e6-e6.  
    07-07-2023
  • Constriction imposed by basement membrane regulates developmental cell migration
    López EM, Kabanova A, Winkel A, Franze K, Palacios IM and Martín-Bermudo MD
    Plos Biology, Public Library of Science vol. 21 (6) 
    28-06-2023
  • ADAMTS3 restricts cancer invasion in models of early breast cancer progression through enhanced fibronectin degradation
    Gibson SV, Madzharova E, Tan AC, Allen MD, Keller UAD, Jones JL, Carter EP and Grose RP
    Matrix Biology, Elsevier vol. 121, 74-89.  
    17-06-2023
  • The gut microbe‐derived methylamine TMAO protects against neuroinflammation through restraint of pro‐inflammatory glial behaviour
    McArthur S
    Alzheimer's & Dementia, Wiley vol. 19 (S1) 
    16-06-2023
  • A guide to functionalisation and bioconjugation strategies to surface-initiated polymer brushes
    Neri-Cruz CE, Teixeira FME and Gautrot JE
    Chemical Communications, Royal Society of Chemistry vol. 59 (49), 7534-7558.  
    09-05-2023
  • Transient deformation of a viscoelastic capsule in a cross-slot microchannel: effects of inertia and membrane viscosity
    Lu RX, Guo ZY, Yu P and Sui Y
    Journal of Fluid Mechanics, Cambridge University Press (Cup) vol. 962 
    03-05-2023
  • 910 Exploring host-microbiome interactions in optimised 3D skin models
    McPolin-Hall E, Stephens A, Pardieu C, Allaker R, Philpott M, Pople J and Hannen R
    Journal of Investigative Dermatology, Elsevier vol. 143 (5) 
    01-05-2023
  • 769 Reduced expression of PPOX, the variegate porphyria gene, causes intrinsic pathological changes to keratinocytes
    Smith CJ, Chan L and Metherell LA
    Journal of Investigative Dermatology, Elsevier vol. 143 (5) 
    01-05-2023
  • DLL4 promotes partial endothelial-to-mesenchymal transition at atherosclerosis-prone regions of arteries
    Li X, Souilhol C, Canham L, Jia X, Diagbouga M, Ayllon BT, Serbanovic-Canic J and Evans PC
    Vascular Pharmacology, Elsevier vol. 150 
    01-05-2023
  • Development of an in vitro microfluidic model to study the role of microenvironmental cells in oral cancer metastasis
    Scemama A, Tailor A, Di Cio S, Dibble M, Gautrot J and Biddle A
    F1000research, Taylor and Francis vol. 12, 439-439.  
    25-04-2023
  • Programmed Self-Assembly of DNA Nanosheets with Discrete Single-Molecule Thickness and Interfacial Mechanics: Design, Simulation, and Characterization.
    Cervantes-Salguero K, Gutiérrez Fosado YA, Megone W, Gautrot JE and Palma M
    Molecules, Mdpi vol. 28 (9) 
    24-04-2023
  • The impact of pericytes on the stability of microvascular networks in response to nanoparticles
    Dibble M, Di Cio’ S, Luo P, Balkwill F and Gautrot JE
    Scientific Reports, Springer Nature vol. 13 (1) 
    07-04-2023
  • Abstract 4576: 3D in vitro models uncover malignant cell intrinsic and extrinsic mechanisms of CAR-T cell resistance in high grade serous ovarian cancer
    Joy JD, Malacrida B, Laforêts F, Kotantaki P, Maniati E, Hopkins S, Garrobo-Calleja I, Gautrot J and Balkwill F
    Cancer Research, American Association For Cancer Research (Aacr) vol. 83 (7_Supplement), 4576-4576.  
    04-04-2023
  • HDAC Inhibition Restores Response to HER2-Targeted Therapy in Breast Cancer via PHLDA1 Induction
    Clayton NS, Carter EP, Fearon AE, Heward JA, Fernández LR, Boughetane L, Wilkes EH, Cutillas PR and Grose RP
    International Journal of Molecular Sciences, Mdpi vol. 24 (7) 
    25-03-2023
  • A method for real-time mechanical characterisation of microcapsules
    Guo Z, Lin T, Jing D, Wang W and Sui Y
    Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 22 (4), 1209-1220.  
    24-03-2023
  • Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
    Bort ET, Joseph MD, Wang Q, Carter EP, Roth NJ, Gibson J, Samadi A, Kocher HM, Simoncelli S, McCormick PJ and Grose RP
    Elife, Elife vol. 12 
    21-03-2023
  • Growth of mesenchymal stem cells at the surface of silicone, mineral and plant-based oils
    Peng L, Nadal C and Gautrot JE
    Biomedical Materials, Iop Publishing vol. 18 (3) 
    17-03-2023
  • Mechano-biological and bio-mechanical pathways in cutaneous wound healing
    Pensalfini M and Tepole AB
    Plos Computational Biology, Public Library of Science (Plos) vol. 19 (3) 
    09-03-2023
  • 3D Compartmentalised Human Pluripotent Stem Cell–derived Neuromuscular Co-cultures
    Harley P, Paredes-Redondo A, Grenci G, Viasnoff V, Lin Y-Y and Lieberam I
    Bio-Protocol vol. 13 (5), e4624-e4624.  
    05-03-2023
  • TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression
    Gibson SV, Tomas Bort E, Rodríguez-Fernández L, Allen MD, Gomm JJ, Goulding I, auf dem Keller U, Agnoletto A, Brisken C, Peck B, Cameron AJ, Marshall JF, Jones JL, Carter EP and Grose RP
    Npj Breast Cancer, Springer Nature vol. 9 (1) 
    02-03-2023
  • Ichthyosis linked to sphingosine 1-phosphate lyase insufficiency is due to aberrant sphingolipid and calcium regulation
    Smith CJ, Williams JL, Hall C, Casas J, Caley MP, O'Toole EA, Prasad R and Metherell LA
    Journal of Lipid Research, Elsevier vol. 64 (4) 
    02-03-2023
  • A computational model for the transit of a cancer cell through a constricted microchannel
    Wang Z, Lu R, Wang W, Tian FB, Feng JJ and Sui Y
    Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 22 (4), 1129-1143.  
    28-02-2023
  • Mesenchymal Stem Cells Sense the Toughness of Nanomaterials and Interfaces
    Peng L, Matellan C, Bosch‐Fortea M, Gonzalez‐Molina J, Frigerio M, Salentinig S, del Rio Hernandez A and Gautrot JE
    Advanced Healthcare Materials, Wiley vol. 12 (13) 
    21-02-2023
  • Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis
    Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN and Perretti M
    Jci Insight, American Society For Clinical Investigation vol. 8 (3) 
    08-02-2023
  • Everybody needs good neighbours: the progressive DCIS microenvironment
    Gibson SV, Roozitalab RM, Allen MD, Jones JL, Carter EP and Grose RP
    Trends in Cancer, Elsevier vol. 9 (4), 326-338.  
    02-02-2023
  • Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening
    Hayat A, Carter EP, King HW, Ors A, Doe A, Teijeiro SA, Charrot S, Godinho S, Cutillas P, Mohammed H, Grose RP and Ficz G
    Disease Models & Mechanisms, The Company of Biologists vol. 16 (2) 
    01-02-2023
  • Mechanical Evaluation of Hydrogel–Elastomer Interfaces Generated through Thiol–Ene Coupling
    Nguyen KDQ, Dejean S, Nottelet B and Gautrot JE
    Acs Applied Polymer Materials, American Chemical Society (Acs) vol. 5 (2), 1364-1373.  
    30-01-2023
  • A novel bioactive glass/graphene oxide composite coating for a polyether ether ketone‐based dental implant
    Al‐Noaman A and Rawlinson SCF
    European Journal of Oral Sciences, Wiley vol. 131 (2) 
    27-01-2023
  • Co-Surfactant-Free Bioactive Protein Nanosheets for the Stabilization of Bioemulsions Enabling Adherent Cell Expansion
    Chrysanthou A, Bosch-Fortea M and Gautrot JE
    Biomacromolecules, American Chemical Society (Acs) vol. 24 (10), 4465-4477.  
    23-01-2023
  • Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK
    Nolan J, Pearce OMT, Screen HRC, Knight MM and Verbruggen SW
    Cancers, Mdpi vol. 15 (3) 
    19-01-2023
  • Supercharged Protein Nanosheets for Cell Expansion on Bioemulsions
    Chrysanthou A, Kanso H, Zhong W, Shang L and Gautrot JE
    Acs Applied Materials & Interfaces, American Chemical Society (Acs) vol. 15 (2), 2760-2770.  
    04-01-2023
  • A host-gut microbial amino acid co-metabolite, p-cresol glucuronide, promotes blood-brain barrier integrity in vivo.
    Stachulski AV, Knausenberger TB-A, Shah SN, Hoyles L and McArthur S
    Tissue Barriers vol. 11 (1), 2073175-2073175.  
    02-01-2023
  • Three-dimensional numerical analysis of wall stress induced by asymmetric oscillation of microbubble trains inside micro-vessels
    Ri J, Pang N, Bai S, Xu J, Xu L, Ri S, Yao Y and Greenwald SE
    Physics of Fluids, Aip Publishing vol. 35 (1) 
    01-01-2023
  • Machine learning and disease prediction in obstetrics
    Arain Z, Iliodromiti S, Slabaugh G, David AL and Chowdhury TT
    Current Research in Physiology, Elsevier vol. 6 
    01-01-2023
  • In silico targeting of colony-stimulating factor-1 receptor: delineating immunotherapy in cancer
    Azhar Z, Grose RP, Raza A and Raza Z
    Exploration of Targeted Anti-Tumor Therapy, Open Exploration Publishing vol. 4 (4), 727-742.  
    01-01-2023