Publications
The following journal papers published by the members of the CPM, specifically relate to the development and/or use of predictive in vitro models.
- The Annexin-A1 mimetic RTP-026 promotes acute cardioprotection through modulation of immune cell activation
Chen J, Oggero S, Cecconello C, Dalli J, Hayat H, Hjiej Andaloussi A, Sanni S, Jonassen TEN et al.
Pharmacological Research, Elsevier Bv vol. 198, 107005-107005.
01-12-2023 - Controlled electroactive release from solid-state conductive elastomer electrodes
Chapman CAR, Fernandez-Patel S, Jahan N, Cuttaz EA, Novikov A, Goding JA, Green RA
Materials Today Bio, Elsevier Bv vol. 23, 100883-100883.
01-12-2023 - Titanium Dioxide/Graphene Oxide Composite Coatings for 316 Stainless Steel Dental Implants.
Al-Noaman AS
European Journal of Prosthodontics and Restorative Dentistry vol. 31 (4), 358-372.
30-11-2023 - Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion
Aguirre GA, Goulart MR, Dalli J, Kocher HM
Frontiers in Immunology, Frontiers Media Sa vol. 14
16-11-2023 - A Novel Primary Cilium‐Mediated Mechanism Through which Osteocytes Regulate Metastatic Behavior of Both Breast and Prostate Cancer Cells
Verbruggen SW, Nolan J, Duffy MP, Pearce OMT, Jacobs CR, Knight MM
Advanced Science, Wiley vol. 11 (2), 2305842-2305842.
15-11-2023 - Mucosal Immunity to Gut Fungi in Health and Inflammatory Bowel Disease
Carlson SL, Mathew L, Savage M, Kok K, Lindsay JO, Munro CA, McCarthy NE
Journal of Fungi, Mdpi vol. 9 (11)
14-11-2023 - CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells
Samain R, Maiques O, Monger J, Lam H, Candido J, George S, Ferrari N, KohIhammer L et al.
Science Advances, American Association For The Advancement of Science (Aaas) vol. 9 (42)
18-10-2023 - Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment
Thompson CL, Hopkins T, Bevan C, Screen HRC, Wright KT, Knight MM
Biomedical Materials, Iop Publishing vol. 18 (6)
10-10-2023 - P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes
Beltran-Lobo P, Hughes MM, Troakes C, Croft CL, Rupawala H, Jutzi D, Ruepp M-D, Jimenez-Sanchez M et al.
Brain Behavior and Immunity, Elsevier vol. 114, 414-429.
15-09-2023 - In silico targeting of colony-stimulating factor-1 receptor: delineating immunotherapy in cancer
Azhar Z, Grose RP, Raza A, Raza Z
Exploration of Targeted Anti-Tumor Therapy, Open Exploration Publishing, 727-742.
31-08-2023 - Cx43 regulates mechanotransduction mechanisms in human preterm amniotic membrane defects
Costa E, Thrasivoulou C, Becker DL, Deprest JA, David AL, Chowdhury TT
Prenatal Diagnosis, Wiley
30-08-2023 - The Future of Precision Oncology
Rulten SL, Grose RP, Gatz SA, Jones JL, Cameron AJM
International Journal of Molecular Sciences, Mdpi Ag vol. 24 (16), 12613-12613.
09-08-2023 - Nonaffine Mechanics of Entangled Networks Inspired by Intermediate Filaments
Pensalfini M, Golde T, Trepat X, Arroyo M
Physical Review Letters, American Physical Society (Aps) vol. 131 (5)
04-08-2023 - Polyether ether ketone coated with nanohydroxyapatite/graphene oxide composite promotes bioactivity and antibacterial activity at the surface of the material
Al‐Noaman A, Rawlinson SCF
European Journal of Oral Sciences, Wiley vol. 131 (5-6)
02-08-2023 - ADAMTS3 restricts cancer invasion in models of early breast cancer progression through enhanced fibronectin degradation
Gibson SV, Madzharova E, Tan AC, Allen MD, Keller UAD, Louise Jones J, Carter EP, Grose RP
Matrix Biology, Elsevier Bv vol. 121, 74-89.
01-08-2023 - Core–Shell-Structured Electrorheological Fluid with a Polarizability-Tunable Nanocarbon Shell for Enhanced Stimuli-Responsive Activity
Chen S, Cheng Y, Zhao Z, Zhang K, Hao T, Sui Y, Wang W, Zhao J et al.
Acs Applied Materials & Interfaces, American Chemical Society (Acs) vol. 15 (29), 35741-35749.
14-07-2023 - O06 Exploring host–microbiome–immune interactions using singular and multispecies inoculations in optimized 3D skin models
McPolin-Hall E, Stephen A, Pardieu C, Allaker R, Philpott M, Bhogal R, Pople J, Hannen R
British Journal of Dermatology, Oxford University Press (Oup) vol. 189 (1), e6-e6.
07-07-2023 - Constriction imposed by basement membrane regulates developmental cell migration
López EM, Kabanova A, Winkel A, Franze K, Palacios IM, Martín-Bermudo MD
Plos Biology, Public Library of Science vol. 21 (6)
28-06-2023 - The gut microbe‐derived methylamine TMAO protects against neuroinflammation through restraint of pro‐inflammatory glial behaviour
McArthur S
Alzheimer's &Amp; Dementia, Wiley vol. 19 (S1)
01-06-2023 - DLL4 promotes partial endothelial-to-mesenchymal transition at atherosclerosis-prone regions of arteries
Li X, Souilhol C, Canham L, Jia X, Diagbouga M, Ayllon BT, Serbanovic-Canic J, Evans PC
Vascular Pharmacology, Elsevier Bv vol. 150, 107178-107178.
01-06-2023 - A guide to functionalisation and bioconjugation strategies to surface-initiated polymer brushes
Neri-Cruz CE, Teixeira FME, Gautrot JE
Chemical Communications, Royal Society of Chemistry vol. 59 (49), 7534-7558.
09-05-2023 - Transient deformation of a viscoelastic capsule in a cross-slot microchannel: effects of inertia and membrane viscosity
Lu RX, Guo ZY, Yu P, Sui Y
Journal of Fluid Mechanics, Cambridge University Press (Cup) vol. 962
03-05-2023 - 769 Reduced expression of PPOX, the variegate porphyria gene, causes intrinsic pathological changes to keratinocytes
Smith CJ, Chan L, Metherell LA
Journal of Investigative Dermatology, Elsevier vol. 143 (5)
01-05-2023 - 910 Exploring host-microbiome interactions in optimised 3D skin models
McPolin-Hall E, Stephens A, Pardieu C, Allaker R, Philpott M, Pople J, Hannen R
Journal of Investigative Dermatology, Elsevier vol. 143 (5)
01-05-2023 - Development of an in vitro microfluidic model to study the role of microenvironmental cells in oral cancer metastasis
Scemama A, Tailor A, Di Cio S, Dibble M, Gautrot J, Biddle A
F1000research, F1000 Research Ltd vol. 12, 439-439.
25-04-2023 - Programmed Self-Assembly of DNA Nanosheets with Discrete Single-Molecule Thickness and Interfacial Mechanics: Design, Simulation, and Characterization.
Cervantes-Salguero K, Gutiérrez Fosado YA, Megone W, Gautrot JE, Palma M
Molecules, Mdpi vol. 28 (9)
24-04-2023 - Engineering Biofouling Resistant Materials Through the Systematic Adaptation of Surface Morphology
Sadler E, Stephen AS, Allaker RP, Crick CR
Advanced Materials Interfaces vol. 10 (12)
24-04-2023 - The impact of pericytes on the stability of microvascular networks in response to nanoparticles
Dibble M, Di Cio’ S, Luo P, Balkwill F, Gautrot JE
Scientific Reports, Springer Nature vol. 13 (1)
07-04-2023 - Abstract 4576: 3D in vitro models uncover malignant cell intrinsic and extrinsic mechanisms of CAR-T cell resistance in high grade serous ovarian cancer
Joy JD, Malacrida B, Laforêts F, Kotantaki P, Maniati E, Hopkins S, Garrobo-Calleja I, Gautrot J et al.
Cancer Research, American Association For Cancer Research (Aacr) vol. 83 (7_Supplement), 4576-4576.
04-04-2023 - Everybody needs good neighbours: the progressive DCIS microenvironment
Gibson SV, Roozitalab RM, Allen MD, Jones JL, Carter EP, Grose RP
Trends in Cancer, Elsevier Bv vol. 9 (4), 326-338.
01-04-2023 - HDAC Inhibition Restores Response to HER2-Targeted Therapy in Breast Cancer via PHLDA1 Induction
Clayton NS, Carter EP, Fearon AE, Heward JA, Rodríguez Fernández L, Boughetane L, Wilkes EH, Cutillas PR et al.
International Journal of Molecular Sciences, Mdpi Ag vol. 24 (7), 6228-6228.
25-03-2023 - A method for real-time mechanical characterisation of microcapsules
Guo Z, Lin T, Jing D, Wang W, Sui Y
Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 22 (4), 1209-1220.
24-03-2023 - Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
Tomas Bort E, Joseph MD, Wang Q, Carter EP, Roth NJ, Gibson J, Samadi A, Kocher HM et al.
Elife, Elife Sciences Publications, Ltd vol. 12
21-03-2023 - Growth of mesenchymal stem cells at the surface of silicone, mineral and plant-based oils
Peng L, Nadal C, Gautrot JE
Biomedical Materials, Iop Publishing vol. 18 (3)
17-03-2023 - Mechano-biological and bio-mechanical pathways in cutaneous wound healing
Pensalfini M, Tepole AB
Plos Computational Biology, Public Library of Science (Plos) vol. 19 (3)
09-03-2023 - 3D Compartmentalised Human Pluripotent Stem Cell–derived Neuromuscular Co-cultures
Harley P, Paredes-Redondo A, Grenci G, Viasnoff V, Lin Y-Y, Lieberam I
Bio-Protocol vol. 13 (5), e4624-e4624.
05-03-2023 - TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression
Gibson SV, Tomas Bort E, Rodríguez-Fernández L, Allen MD, Gomm JJ, Goulding I, auf dem Keller U, Agnoletto A et al.
Npj Breast Cancer, Springer Science and Business Media Llc vol. 9 (1)
02-03-2023 - Ichthyosis linked to sphingosine 1-phosphate lyase insufficiency is due to aberrant sphingolipid and calcium regulation
Smith CJ, Williams JL, Hall C, Casas J, Caley MP, O'Toole EA, Prasad R, Metherell LA
Journal of Lipid Research, Elsevier vol. 64 (4)
02-03-2023 - Photoelectrochemical imaging of single cardiomyocytes and monitoring of their action potentials through contact force manipulation of organoids
Jacques R, Zhou B, Marhuenda E, Gorecki J, Das A, Iskratsch T, Krause S
Biosensors and Bioelectronics, Elsevier Bv vol. 223, 115024-115024.
01-03-2023 - A computational model for the transit of a cancer cell through a constricted microchannel
Wang Z, Lu R, Wang W, Tian FB, Feng JJ, Sui Y
Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 22 (4), 1129-1143.
28-02-2023 - Mesenchymal Stem Cells Sense the Toughness of Nanomaterials and Interfaces
Peng L, Matellan C, Bosch‐Fortea M, Gonzalez‐Molina J, Frigerio M, Salentinig S, del Rio Hernandez A, Gautrot JE
Advanced Healthcare Materials, Wiley vol. 12 (13)
21-02-2023 - Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al.
Jci Insight, American Society For Clinical Investigation vol. 8 (3)
08-02-2023 - Mechanical Evaluation of Hydrogel–Elastomer Interfaces Generated through Thiol–Ene Coupling
Nguyen KDQ, Dejean S, Nottelet B, Gautrot JE
Acs Applied Polymer Materials, American Chemical Society (Acs) vol. 5 (2), 1364-1373.
30-01-2023 - A novel bioactive glass/graphene oxide composite coating for a polyether ether ketone‐based dental implant
Al‐Noaman A
European Journal of Oral Sciences, Wiley vol. 131 (2)
27-01-2023 - Co-Surfactant-Free Bioactive Protein Nanosheets for the Stabilization of Bioemulsions Enabling Adherent Cell Expansion
Chrysanthou A, Bosch-Fortea M, Gautrot JE
Biomacromolecules, American Chemical Society (Acs) vol. 24 (10), 4465-4477.
23-01-2023 - Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK
Nolan J, Pearce OMT, Screen HRC, Knight MM, Verbruggen SW
Cancers, Mdpi vol. 15 (3)
19-01-2023 - Supercharged Protein Nanosheets for Cell Expansion on Bioemulsions
Chrysanthou A, Kanso H, Zhong W, Shang L, Gautrot JE
Acs Applied Materials & Interfaces, American Chemical Society (Acs) vol. 15 (2), 2760-2770.
04-01-2023 - Machine learning and disease prediction in obstetrics
Arain Z, Iliodromiti S, Slabaugh G, David AL, Chowdhury TT
Current Research in Physiology, Elsevier vol. 6
01-01-2023 - Three-dimensional numerical analysis of wall stress induced by asymmetric oscillation of microbubble trains inside micro-vessels
Ri J, Pang N, Bai S, Xu J, Xu L, Ri S, Yao Y, Greenwald SE
Physics of Fluids, Aip Publishing vol. 35 (1)
01-01-2023