Publications
The following journal papers published by the members of the CPM, specifically relate to the development and/or use of predictive in vitro models.
- Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide
Hoyles L, Pontifex M, Rodriguez-Ramiro I, Anis-Alavi MA, Jelane KS, Snelling T, Solito E, Fonseca S et al.
Microbiome, Biomed Central
27-11-2021 - Long term expansion profile of mesenchymal stromal cells at protein nanosheet-stabilised bioemulsions for next generation cell culture microcarriers
Peng L, Gautrot JE
Materials Today Bio, Elsevier vol. 12, 100159-100159.
16-11-2021 - Biological Significance and Targeting of the FGFR Axis in Cancer
Chioni A-M, Grose RP
Cancers, Mdpi Ag vol. 13 (22), 5681-5681.
13-11-2021 - Competitive binding and molecular crowding regulate the cytoplasmic interactome of non-viral polymeric gene delivery vectors
Raynold AAM, Li D, Chang L, Gautrot JE
Nature Communications, Springer Nature vol. 12 (1)
08-11-2021 - Mannose Metabolism Is a Metabolic Vulnerability Unveiled By Standard and Novel Therapies in Acute Myeloid Leukemia
Woodley K, Dillingh LS, Giotopoulos G, Madrigal P, Tzelepis K, Philippe C, Rattigan K, Asby R et al.
Blood, American Society of Hematology vol. 138 (Supplement 1)
05-11-2021 - Tumour microenvironment 3D-modelling: simplicity to complexity and back again
Carter EP, Roozitalab R, Gibson SV, Grose RP
Trends in Cancer, Elsevier Bv vol. 7 (11), 1033-1046.
01-11-2021 - Ultrafast Photo-Crosslinking of Thiol–Norbornene Opaque Silicone Elastomer Nanocomposites in Air
Nguyen KDQ, Crespo-Ribadeneyra M, Picot O, Colak B, Gautrot JE
Acs Applied Polymer Materials, American Chemical Society
19-10-2021 - Quantitative Super-Resolution Imaging for the Analysis of GPCR Oligomerization
Joseph MD, Tomas Bort E, Grose RP, McCormick PJ, Simoncelli S
Biomolecules, Mdpi Ag vol. 11 (10), 1503-1503.
12-10-2021 - 099 Ichthyosis associated with sphingosine 1-phosphate lyase deficiency is due to aberrant calcium and sphingolipid regulation
Smith CJ, Williams JL, Caley MP, O’Toole EA, Prasad R, Metherell LA
Journal of Investigative Dermatology vol. 141 (10), s165-s165.
07-10-2021 - Optogenetic modeling of human neuromuscular circuits in Duchenne muscular dystrophy with CRISPR and pharmacological corrections
Paredes-Redondo A, Harley P, Maniati E, Ryan D, Louzada S, Meng J, Kowala A, Fu B et al.
Science Advances vol. 7 (37)
10-09-2021 - Cx43 mediates changes in myofibroblast contraction and collagen release in human amniotic membrane defects after trauma
Costa E, Okesola BO, Thrasivoulou C, Becker DL, Deprest JA, David AL, Chowdhury TT
Scientific Reports, Springer Nature vol. 11 (1)
18-08-2021 - Tuning Electrostatic Gating of Semiconducting Carbon Nanotubes by Controlling Protein Orientation in Biosensing Devices
Xu X, Bowen BJ, Gwyther REA, Freeley M, Grigorenko B, Nemukhin AV, Eklöf‐Österberg J, Moth‐Poulsen K et al.
Angewandte Chemie International Edition, Wiley vol. 60 (37), 20184-20189.
06-08-2021 - A Scarless Healing Tale: Comparing Homeostasis and Wound Healing of Oral Mucosa With Skin and Oesophagus
Pereira D, Sequeira I
Frontiers in Cell and Developmental Biology, Frontiers vol. 9
26-07-2021 - Impact of the molecular structure of cationic binders on the rheological and adhesive properties of carboxymethyl cellulose-based coacervate hydrogels
Megone W, Tang P, Roohpour N
Arkivoc, Arkat Usa vol. 2021 (6), 101-119.
21-07-2021 - DNA-Directed Assembly of Carbon Nanotube–Protein Hybrids
Freeley M, Gwyther REA, Jones DD, Palma M
Biomolecules, Mdpi Ag
29-06-2021 - The Mechanical Interplay Between Differentiating Mesenchymal Stem Cells and Gelatin-Based Substrates Measured by Atomic Force Microscopy
Meng H, Chowdhury TT, Gavara N
Frontiers in Cell and Developmental Biology, Frontiers vol. 9
21-06-2021 - Cationic Polymer Brush-Coated Bioglass Nanoparticles for the Design of Bioresorbable RNA Delivery Vectors
Chang L, Yan H, Chang J, Gautrot JE
European Polymer Journal, Elsevier, 110593-110593.
13-06-2021 - Mechanical Stimulation Modulates Osteocyte Regulation of Cancer Cell Phenotype
Verbruggen SW, Thompson CL, Duffy MP, Lunetto S, Nolan J, Pearce OMT, Jacobs CR, Knight MM
Cancers, Mdpi vol. 13 (12)
10-06-2021 - Aortic pressure waveform reconstruction using a multi-channel Newton blind system identification algorithm
Liu W, Li Z, Wang Y, Song D, Ji N, Xu L, Mei T, Sun Y et al.
Computers in Biology and Medicine, Elsevier vol. 135
08-06-2021 - A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion
Malacrida B, Nichols S, Maniati E, Jones R, Delanie-Smith R, Roozitalab R, Tyler EJ, Thomas M et al.
Iscience, Elsevier vol. 24 (6)
29-05-2021 - Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer
Delaine-Smith RM, Maniati E, Malacrida B, Nichols S, Roozitalab R, Jones RR, Lecker LSM, Pearce OMT et al.
Iscience, Elsevier vol. 24 (6)
29-05-2021 - Loss of 15-lipoxygenase disrupts Treg differentiation altering their pro-resolving functions
Marques RM, Gonzalez-Nunez M, Walker ME, Gomez EA, Colas RA, Montero-Melendez T, Perretti M, Dalli J
Cell Death &Amp; Differentiation, Springer Science and Business Media Llc vol. 28 (11), 3140-3160.
27-05-2021 - Programmed death ligand 2 expression plays a limited role in adenocarcinomas of the gastroesophageal junction after preoperative chemotherapy
Jomrich G, Kollmann D, Wilfing L, Radosavljevic S, Ramazanova D, Ristl R, Grose RP, Ilhan-Mutlu A et al.
European Surgery, Springer Science and Business Media Llc vol. 53 (6), 287-293.
05-05-2021 - In Vitro Splicing Assay Proves the Pathogenicity of Intronic Variants in MRAP
Smith C, Maharaj AV, Qamar Y, Read J, Williams J, Chan L, Marimuthu V, Metherell L
Journal of The Endocrine Society vol. 5 (Suppl 1), a85-a86.
03-05-2021 - Towards More Predictive, Physiological and Animal-free In Vitro Models: Advances in Cell and Tissue Culture 2020 Conference Proceedings
Singh B, Abdelgawad ME, Ali Z, Bailey J, Budyn E, Civita P, Clift MJD, Connelly JT et al.
Alternatives to Laboratory Animals, Sage Publications vol. 49 (3), 93-110.
01-05-2021 - Photoelectrochemical imaging system with high spatiotemporal resolution for visualizing dynamic cellular responses
Zhou B, Das A, Zhong M, Guo Q, Zhang D-W, Hing KA, Sobrido AJ, Titirici M-M et al.
Biosensors and Bioelectronics, Elsevier Bv vol. 180, 113121-113121.
01-05-2021 - Sub-toxic levels of cobalt ions impair mechanostranduction via HDAC6-depedent primary cilia shortening.
Wu H, Wang Z, Liu S, Meng H, Liu S, Shelton JC, Thompson CL, Fu S et al.
Biochem Biophys Res Commun
15-04-2021 - Dissecting FGF Signalling to Target Cellular Crosstalk in Pancreatic Cancer
Carter EP, Coetzee AS, Tomas Bort E, Wang Q, Kocher HM, Grose RP
Cells, Mdpi Ag vol. 10 (4), 847-847.
08-04-2021 - A novel capsule-based smell test fabricated via coaxial dripping
Ismail AS, Goodwin GR, Castrejon-Pita JR, Noyce AJ, Azevedo HS
Journal of The Royal Society Interface, The Royal Society vol. 18 (177)
01-04-2021 - Alpha‐1‐antitrypsin reduces inflammation and exerts chondroprotection in arthritis
Kaneva MK, Muley MM, Krustev E, Reid AR, Souza PR, Dell’Accio F, McDougall JJ, Perretti M
The Faseb Journal, Wiley vol. 35 (5)
31-03-2021 - Extreme reversal in mechanical anisotropy in liquid-liquid interfaces reinforced with self-assembled protein nanosheets
Megone W, Kong D, Peng L, Gautrot JE
Journal of Colloid and Interface Science, Elsevier vol. 594, 650-657.
17-03-2021 - Regulation of collective cell polarity and migration using dynamically adhesive micropatterned substrates
Costa P, Blowes LM, Laly AC, Connelly JT
Acta Biomaterialia, Elsevier vol. 126, 291-300.
16-03-2021 - Corrigendum: Mechanical Stimulation: A Crucial Element of Organ-on-Chip Models
Thompson CL, Fu S, Heywood HK, Knight MM, Thorpe SD
Frontiers in Bioengineering and Biotechnology, Frontiers Media Sa vol. 9
18-02-2021 - Precise positioning of enzymes within hierarchical polymer nanostructures for switchable bioelectrocatalysis.
Qu F, Ma X, Gautrot JE
Biosensors and Bioelectronics, Elsevier vol. 179, 113045-113045.
18-02-2021 - Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption
Adams SD, Csere J, D’angelo G, Carter EP, Romao M, Arnandis T, Dodel M, Kocher HM et al.
Current Biology, Elsevier vol. 31 (7), 1403-1416.e7.
15-02-2021 - Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer
Delaine-Smith R, Maniati E, Malacrida B, Nichols S, Roozitalab R, Jones R, Lecker L, Pearce O et al.
Biorxiv.Org
02-02-2021 - The keratin network of intermediate filaments regulates keratinocyte rigidity sensing and nuclear mechanotransduction
Laly AC, Sliogeryte K, Pundel OJ, Ross R, Keeling MC, Avisetti D, Waseem A, Gavara N et al.
Science Advances, American Association For The Advancement of Science (Aaas) vol. 7 (5)
27-01-2021 - Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions
Croft CL, Goodwin MS, Ryu DH, Lessard CB, Tejeda G, Marrero M, Vause AR, Paterno G et al.
Acta Neuropathologica, Springer Nature vol. 141 (3), 359-381.
26-01-2021 - Comparative Adhesion of Chemically and Physically Crosslinked Poly(Acrylic Acid)-Based Hydrogels to Soft Tissues
Cozens EJ, Roohpour N, Gautrot JE
European Polymer Journal, Elsevier, 110250-110250.
18-01-2021 - Chapter 11 Recent Advances in the Design of Surface-initiated Polymer Brushes for Biomedical Applications
Qu F, Raynold AM
In Soft Matter For Biomedical Applications, Royal Society of Chemistry (Rsc) 264-300.
01-01-2021 - Hallmarks of cancer—the new testament
Senga SS, Grose RP
Open Biology, The Royal Society vol. 11 (1)
01-01-2021