Research at the QM+Emulate Centre

The Queen Mary+Emulate Organs-on-Chips Centre hosts an expanding range of research and development projects. The Centre has helped win over £1M of research funding in the last 6 months. The Centre is open for use by external academic institutions and industry and can help support research projects by providing access to Emulate facilities, support from our Centre Scientists and routes to commercialisation.

Current projects include the following:

Organ-on-a-chip models for safety testing of regenerative medicine products MRC Project Grant (2020-2024) £506,621 Hazel Screen (PI), Martin Knight, Elica el Haj Queen Mary University of London Further information
Organ-on-a-chip model to investigate breast cancer bone metastases CRUK & EPSRC Multidisciplinary Award (2021-2023) £269,601 Martin Knight (PI), Oliver Pearce Queen Mary University of London
Understanding the mechanisms of vascular dysfunction in severe COVID-19 Covid Initiative Fund Prof Daniel Pennington (PI), Dr Neil McCarthy (CoI) Barts and The London School of Medicine and Dentistry
Development of a organ-on-a-chip model for bone  BBSRC LIDo PhD Studentship (Rotation project) Martin Knight (PI), Cleo Bishop (CoI), Stefaan Verbruggen Queen Mary University of London
Development of a synovium-chondrocyte organ-on-a-chip model with integrated biomechanical stimulation  EPSRC OA Tech Network Plus - Pump Priming Grant (2019-2020) £9,068 Hazel Screen (PI), Clare Thompson Queen Mary University of London
Mechanical regulation of synociocyte response to pro-inflammatory cytokines CONACyT PhD Studentship (2019-2023) Martin Knight (PI), Hazel Screen, Clare Thompson Queen Mary University of London
Novel Models of Tendinopathy on a Chip CONACyT PhD Studentship (2019-2023) Hazel Screen (PI), Martin Knight, Clare Thompson Queen Mary University of London