Prof David Lee

David Lee

Professor of Cell & Tissue Engineering

School of Engineering and Materials Science
Queen Mary University of London
www.sems.qmul.ac.uk/staff/d.a.lee

Research

Mechanobiology, Stem cell biology, Circadian biology, Musculoskeletal, Energy metabolism, Cartilage

Underpinning Bioengineering, Cancer Models, Cardiovascular Models, Musculoskeletal Models

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2022

Modulation of sirtuins during monolayer chondrocyte culture influences cartilage regeneration upon transfer to a 3D culture environment
Heywood HK, Thorpe SD, Jeropoulos RM, Caton PW, Lee DA
Frontiers in Bioengineering and Biotechnology, Frontiers Media Sa vol. 10 
06-12-2022
Oscillations of the circadian clock protein, BMAL-1, align to daily cycles of mechanical stimuli: a novel means to integrate biological time within predictive in vitro model systems
Heywood HK, Gardner L, Knight MM, Lee DA
In Vitro Models, Springer Science and Business Media Llc vol. 1 (6), 405-412.  
31-08-2022
Covariation of Pluripotency Markers and Biomechanical Properties in Mouse Embryonic Stem Cells
Brookes O, Thorpe SD, Rigby Evans O, Keeling MC, Lee DA
Frontiers in Cell and Developmental Biology, Frontiers Media Sa vol. 10 
16-05-2022

2020

G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell Polarization
Lachowski D, Cortes E, Matellan C, Rice A, Lee DA, Thorpe SD, del Río Hernández AE
Frontiers in Cell and Developmental Biology, Frontiers Media Sa vol. 8 
22-10-2020
GPER Activation Inhibits Cancer Cell Mechanotransduction and Basement Membrane Invasion via RhoA
Rice A, Cortes E, Lachowski D, Oertle P, Matellan C, Thorpe SD, Ghose R, Wang H et al.
Cancers, Mdpi Ag vol. 12 (2), 289-289.  
25-01-2020
Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway
Chronopoulos A, Thorpe SD, Cortes E, Lachowski D, Rice AJ, Mykuliak VV, Róg T, Lee DA et al.
Nature Materials, Springer Science and Business Media Llc vol. 19 (6), 669-678.  
06-01-2020

2018

Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor
Cortes E, Lachowski D, Rice A, Thorpe SD, Robinson B, Yeldag G, Lee DA, Ghemtio L et al.
Oncogene, Springer Science and Business Media Llc vol. 38 (16), 2910-2922.  
21-12-2018
Retinoic Acid Receptor‐β Is Downregulated in Hepatocellular Carcinoma and Cirrhosis and Its Expression Inhibits Myosin‐Driven Activation and Durotaxis in Hepatic Stellate Cells
Cortes E, Lachowski D, Rice A, Chronopoulos A, Robinson B, Thorpe S, Lee DA, Possamai LA et al.
Hepatology, Ovid Technologies (Wolters Kluwer Health) vol. 69 (2), 785-802.  
17-12-2018
Tamoxifen mechanically reprograms the tumor microenvironment via\n HIF\n ‐1A and reduces cancer cell survival
Cortes E, Lachowski D, Robinson B, Sarper M, Teppo JS, Thorpe SD, Lieberthal TJ, Iwamoto K et al.
Embo Reports, Springer Science and Business Media Llc vol. 20 (1) 
12-12-2018
GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment
Cortes E, Sarper M, Robinson B, Lachowski D, Chronopoulos A, Thorpe SD, Lee DA, del Río Hernández AE
Embo Reports, Springer Science and Business Media Llc vol. 20 (1) 
11-12-2018

2017

Development of a two-stage gene selection method that incorporates a novel hybrid approach using the cuckoo optimization algorithm and harmony search for cancer classification
Elyasigomari V, Lee DA, Screen HRC, SHAHEED MH
Journal of Biomedical Informatics vol. 67 (2017), 11-20.  
03-02-2017
Dynamic regulation of nuclear architecture and mechanics—a rheostatic role for the nucleus in tailoring cellular mechanosensitivity
Thorpe SD, Lee DA
Nucleus, Informa Uk Limited vol. 8 (3), 287-300.  
02-02-2017
Does lamin A/C play a role in neuronal differentiation?
Eraifej J, Thorpe SD, Martins RP, Lee DA
 
01-01-2017
Stem cell differentiation state modulates Lamin AC localization and phosphorylation in response to cyclic tensile strain
Thorpe SD, Oti A, Mauck RL, Lee DA
 
01-01-2017
Small molecule activators of SIRT1 augment the regenerative potential of chondrocytes for cell-based cartilage repair techniques
Heywood HK, Thorpe SD, Jeropoulos RM, Lee DA
 
01-01-2017
Uniaxial tensile strain modulates mesenchymal stem cell nuclear structure and histone methylation in a differentiation dependent manner
Panesar KS, Thorpe SD, Lee DA
 
01-01-2017

2016

Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity
Heo S-J, Driscoll TP, Thorpe SD, Nerurkar NL, Baker BM, Yang MT, Chen CS, Lee DA et al.
Elife, Elife Sciences Publications, Ltd vol. 5 
30-11-2016
Oxygen tension modulates the effects of TNFα in compressed chondrocytes
Tilwani RK, Vessillier S, Pingguan-Murphy B, Lee DA, Bader DL, Chowdhury TT
Inflammation Research, Springer Science and Business Media Llc vol. 66 (1), 49-58.  
22-09-2016
Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells
Heo S-J, Han WM, Szczesny SE, Cosgrove BD, Elliott DM, Lee DA, Duncan RL, Mauck RL
Biophysical Journal, Elsevier Bv vol. 111 (4), 864-874.  
01-08-2016
Chondrocyte dedifferentiation increases cell stiffness by strengthening membrane-actin adhesion
Sliogeryte K, Botto L, Lee DA, Knight MM
Osteoarthritis and Cartilage, Elsevier Bv vol. 24 (5), 912-920.  
01-05-2016
States rights and Australia’s adoption of the statute of Westminster, 1931–1942
Lee D
History Australia, Informa Uk Limited vol. 13 (2), 258-274.  
02-04-2016
Bioenergetic reprogramming of articular chondrocytes by exposure to exogenous and endogenous reactive oxygen species and its role in the anabolic response to low oxygen
Heywood HK, Lee DA
Journal of Tissue Engineering and Regenerative Medicine, Wiley vol. 11 (8), 2286-2294.  
22-01-2016
Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility
Theocharidis G, Drymoussi Z, Kao AP, Barber AH, Lee DA, Braun KM, Connelly JT
Journal of Investigative Dermatology vol. 136 (1), 74-83.  
01-01-2016
SIRT1, an enzyme vital to cartilage homeostasis, is regulated by osmolarity and glucose levels
Heywood HK, Caton PW, Lee DA
 
01-01-2016

2015

Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells
Heo S-J, Thorpe SD, Driscoll TP, Duncan RL, Lee DA, Mauck RL
Scientific Reports, Springer Science and Business Media Llc vol. 5 (1) 
23-11-2015
FINITE ELEMENT ANALYSIS OF MECHANICAL DEFORMATION OF CHONDROCYTE TO 2D SUBSTRATE AND 3D SCAFFOLD
CHEN J, BADER DL, LEE DA, KNIGHT MM
Journal of Mechanics in Medicine and Biology, World Scientific Pub Co Pte Lt vol. 15 (05), 1550077-1550077.  
01-10-2015
Verket som ble borte – ekfrase som dokumentasjon for ettertiden
Grøttum I, Nødseth IL
Ekfrase, Scandinavian University Press / Universitetsforlaget As vol. 6 (01), 50-54.  
11-05-2015

2014

Stem cell differentiation increases membrane-actin adhesion regulating cell blebability, migration and mechanics
Sliogeryte K, Thorpe SD, Lee DA, Botto L, Knight MM
Scientific Reports, Springer Science and Business Media Llc vol. 4 (1) 
04-12-2014
Quantification of chromatin condensation level by image processing
Irianto J, Lee DA, Knight MM
Medical Engineering &Amp; Physics, Elsevier Bv vol. 36 (3), 412-417.  
01-03-2014
Culture Expansion in Low-Glucose Conditions Preserves Chondrocyte Differentiation and Enhances Their Subsequent Capacity to Form Cartilage Tissue in Three-Dimensional Culture
Heywood HK, Nalesso G, Lee DA, Dell'Accio F
Bioresearch Open Access, Mary Ann Liebert Inc vol. 3 (1), 9-18.  
01-02-2014
Mesenchymal stem cell nuclear architecture is differentially regulated by lineage commitment and mechanical stimulation
Thorpe SD, Lee DA
 
01-01-2014
Reactive oxygen species drive the transformation to an oxidative energy metabolism in cultured articular chondrocytes
Heywood HK, Lee DA
 
01-01-2014
Hypoxia amplified catabolic effects induced by TNFα in chondrocytes - response reduced with biomechanical signals
Tilwani RK, Lee DA, Pingguan-Murphy B, Abas WABW, Chowdhury TT
 
01-01-2014

2013

Osmotic Challenge Drives Rapid and Reversible Chromatin Condensation in Chondrocytes
Irianto J, Swift J, Martins RP, McPhail GD, Knight MM, Discher DE, Lee DA
Biophysical Journal, Elsevier Bv vol. 104 (4), 759-769.  
01-02-2013
Continuous and Uninterrupted Oxygen Tension Influences the Colony Formation and Oxidative Metabolism of Human Mesenchymal Stem Cells
Pattappa G, Thorpe SD, Jegard NC, Heywood HK, de Bruijn JD, Lee DA
Tissue Engineering Part C: Methods, Mary Ann Liebert Inc vol. 19 (1), 68-79.  
01-01-2013
Reluctant relaxation
Lee D
History Australia, Informa Uk Limited vol. 10 (3), 149-170.  
01-01-2013

2012

New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures
Sillitoe I, Cuff AL, Dessailly BH, Dawson NL, Furnham N, Lee D, Lees JG, Lewis TE et al.
Nucleic Acids Research, Oxford University Press (Oup) vol. 41 (D1), D490-D498.  
29-11-2012
Cell Mechanics, Structure, and Function Are Regulated by the Stiffness of the Three-Dimensional Microenvironment
Chen J, Irianto J, Inamdar S, Pravincumar P, Lee DA, Bader DL, Knight MM
Biophysical Journal, Elsevier Bv vol. 103 (6), 1188-1197.  
01-09-2012
Mechanical Regulation of Nuclear Structure and Function
Martins RP, Finan JD, Farshid G, Lee DA
Annual Review of Biomedical Engineering, Annual Reviews vol. 14 (1), 431-455.  
15-08-2012
Dynamic compressive strain influences chondrogenic gene expression in human periosteal cells: A case study
Bonzani IC, Campbell JJ, Knight MM, Williams A, Lee DA, Bader DL, Stevens MM
Journal of The Mechanical Behavior of Biomedical Materials, Elsevier Bv vol. 11, 72-81.  
01-07-2012
Improving metabolic flux predictions using absolute gene expression data
Lee D, Smallbone K, Dunn WB, Murabito E, Winder CL, Kell DB, Mendes P, Swainston N
Bmc Systems Biology, Springer Science and Business Media Llc vol. 6 (1) 
19-06-2012
Through pellicle management of haze formation in a wafer fabrication environment
Figliolini A, Archuletta M, LeClaire J, Brinkley D, Doerr D, White R, Bozak R, Lee DA
28th European Mask and Lithography Conference (EMLC 2012). 
16-04-2012
Stanley Melbourne Bruce in London, 1938–41
Lee D
The Journal of Imperial and Commonwealth History, Informa Uk Limited vol. 40 (1), 45-65.  
01-03-2012
Scaling and mesostructure of Carbopol dispersions
Gutowski IA, Lee D, de Bruyn JR, Frisken BJ
Rheologica Acta, Springer Science and Business Media Llc vol. 51 (5), 441-450.  
18-01-2012
Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading
Maeda E, Ye S, Wang W, Bader DL, Knight MM, Lee DA
Biomechanics and Modeling in Mechanobiology vol. 11 (3-4), 439-447.  
01-01-2012
Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations
Hosny NA, Lee DA, Knight MM
Journal of Biomedical Optics, Spie-Intl Soc Optical Eng vol. 17 (1), 016007-016007.  
01-01-2012
White Globules in Melanocytic Neoplasms: In Vivo and Ex Vivo Characteristics
Jaimes N, Scope A, Welzel J, Wang KX, Lee DA, Siegel DM, Marghoob AA
Dermatologic Surgery, Ovid Technologies (Wolters Kluwer Health) vol. 38 (1), 128-132.  
01-01-2012

2011

The mechanics of flexor tendon adhesions
Branford OA, Lee DA, Bader DL, Grobbelaar AO
Journal of Hand Surgery (European Volume), Sage Publications vol. 37 (6), 555-563.  
14-12-2011
The attachment of intrinsic and extrinsic, mobilized and immobilized adhesion cells to collagen and fibronectin
Branford OA, Lee DA, Rolfe KJ, Grobbelaar AO
Journal of Hand Surgery (European Volume), Sage Publications vol. 37 (6), 564-572.  
17-11-2011
Clean and repair of EUV photomasks
Robinson T, Yi D, Brinkley D, Roessler K, White R, Bozak R, Archuletta M, Lee D
SPIE Photomask Technology. 
06-10-2011
The metabolism of human mesenchymal stem cells during proliferation and differentiation.
Pattappa G, Heywood HK, de Bruijn JD, Lee DA
Journal of Cellular Physiology vol. 226 (10), 2562-2570.  
01-10-2011
Extensive oral herpes simplex virus type 1 infection in a haematopoietic stem cell transplant recipient not responding to aciclovir
Moses SE, Osborne W, Valappil M, Collin M, Lee D, Waugh S, Jackson G, Parry CM et al.
Journal of Clinical Virology, Elsevier Bv vol. 52 (2), 67-69.  
01-10-2011
The Metabolism of Human Mesenchymal Stem Cells During Proliferation and Differentiation
Pattappa G, Heywood HK, De Bruijn JD, Lee DA
J Cell Physiol vol. 226 (10), 2562-2570.  
01-10-2011
Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment.
Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH, Screen HRC
Proc Inst Mech Eng H vol. 225 (8), 821-830.  
01-08-2011
Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading

Biomechanics and Modeling in Mechanobiology, Springer Science and Business Media Llc vol. 11 (3-4), 439-447.  
25-06-2011
Investigating the microstructure of a yield-stress fluid by light scattering
Lee D, Gutowski IA, Bailey AE, Rubatat L, de Bruyn JR, Frisken BJ
Physical Review E, American Physical Society (Aps) vol. 83 (3) 
10-03-2011
Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment
Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH, Screen HRC
P I Mech Eng H vol. 225 (H8), 821-830.  
01-01-2011
Finite Element Modeling of Cell Deformation When Chondrocyte Seeded Agarose Is Subjected to Compression
Chen J, Bader DL, Lee DA, Knight MM
 
01-01-2011
Stem Cell Mechanobiology
Lee DA, Knight MM, Campbell JJ, Bader DL
J Cell Biochem vol. 112 (1), 1-9.  
01-01-2011
1,000 structures and more from the MCSG
Lee D, de Beer TAP, Laskowski RA, Thornton JM, Orengo CA
Bmc Structural Biology, Springer Science and Business Media Llc vol. 11 (1), 2-2.  
01-01-2011
Novel devices for diagnosis and treatment
Lee DA, Siegel DM
Journal of Drugs in Dermatology vol. 10 (1), 21-22.  
01-01-2011
Electrospray deposited fibronectin retains the ability to promote cell adhesion
Martyn SV, Heywood HK, Rockett P, Paine MD, Wang MJ, Dobson PJ, Sheard SJ, Lee DA et al.
J Biomed Mater Res B vol. 96B (1), 110-118.  
01-01-2011

2010

Functional analysis of tenocytes gene expression in tendon fascicles subjected to cyclic tensile strain
Maeda E, Fleischmann C, Mein CA, Shelton JC, Bader DL, Lee DA
Connective Tissue Research vol. 51 (6), 434-444.  
01-12-2010
Quantification of mRNA Using Real-Time PCR and Western Blot Analysis of MAPK Events in Chondrocyte/Agarose Constructs
Lee DA, Brand J, Salter D, Akanji O-O, Chowdhury TT
, Humana Press, 77-97.  
07-10-2010
Both Superficial and Deep Zone Articular Chondrocyte Subpopulations Exhibit the Crabtree Effect But Have Different Basal Oxygen Consumption Rates
Heywood HK, Knight MM, Lee DA
J Cell Physiol vol. 223 (3), 630-639.  
01-06-2010
Giving something back
Lee D
Twist (22), 28-30.  
01-06-2010
Through-pellicle defect repair for advanced photomasks
Robinson T, White R, Bozak R, LeClaire J, Archuletta M, Lee D
Photomask and NGL Mask Technology XVII. 
29-04-2010
Nanomachining of non-orthogonal mask patterns
Robinson T, Yi D, White R, Bozak R, Archuletta M, Lee D
Photomask and NGL Mask Technology XVII. 
29-04-2010
A compartment model to evaluate the permeability of gap junctions between tenocytes in tendon fascicles

The Faseb Journal, Wiley vol. 24 (S1) 
01-04-2010
Preliminary results for photomask haze mitigation in a fab environment
Ku T, LeClaire J, Tan SK, Chua GS, Bozak R, White R, Robinson T, Archuletta M et al.
SPIE Advanced Lithography. 
11-03-2010
Extracellular oxygen concentration mapping with a confocal multiphoton laser scanning microscope and TCSPC card
Hosny NA, Lee DA, Knight MM
BiOS. 
11-02-2010
Low Oxygen Reduces the Modulation to an Oxidative Phenotype in Monolayer-Expaned Chondrocytes
Heywood HK, Lee DA
J Cell Physiol vol. 222 (1), 248-253.  
01-01-2010

2009

Effect of intermittent cyclic tensile strain on collagen synthesis by tenocytes in isolated fascicles
Maeda E, Shelton JC, Bader DL, Lee DA
Journal of Biomechanical Science and Engineering vol. 4 (4), 510-517.  
01-12-2009
GeMMA: functional subfamily classification within superfamilies of predicted protein structural domains
Lee DA, Rentzsch R, Orengo C
Nucleic Acids Research, Oxford University Press (Oup) vol. 38 (3), 720-737.  
18-11-2009
New tools to enable photomask repair to the 32nm node
Robinson T, White R, Bozak R, Roessler K, Arruza B, Hogle D, Archuletta M, Lee D
SPIE Photomask Technology. 
01-10-2009
The effect of oxygen tension on the proliferation and differentiation of human mesenchymal stem cells
Pattappa G, Jegard NC, Lee DA, de Bruijn JD
European Cells and Materials vol. 18 (SUPPL. 1) 
01-08-2009
Osteogenic differentiation of human mesenchymal stem cells within a perfused bioreactor system

European Cells and Materials vol. 18 (SUPPL. 2) 
01-07-2009
The influence of oxygen tension on the colony formation and proliferation of human mesenchymal stem cells
Pattappa G, Jegard NC, de Bruijn JD, Lee DA
European Cells and Materials vol. 18 (SUPPL. 2) 
01-07-2009
Graded hydrogel constructs for cartilage tissue engineering
Mcleod R, Pattappa G, Irianto J, Awan M, Knight MM, Lee DA
 
01-07-2009
Selective removal of persistent particles with no photomask damage
Robinson T, Bozak R, White R, Archuletta M, Lee D
Photomask and NGL Mask Technology XVI. 
24-04-2009
Differential regulation of gene expression in isolated tendon fascicles exposed to cyclic tensile strain in vitro
Maeda E, Shelton JC, Bader DL, Lee DA
Journal of Applied Physiology vol. 106 (2), 506-512.  
01-02-2009
The development of a bioreactor to perfuse radially-confined hydrogel constructs: Design and characterization of mass transport properties
Eniwumide JO, Lee DA, Bader DL
Biorheology vol. 46 (5), 417-437.  
01-01-2009
Cell-generated forces influence the viability, metabolism and mechanical properties of fibroblast-seeded collagen gel constructs.
Berry CC, Shelton JC, Lee DA
J Tissue Eng Regen Med vol. 3 (1), 43-53.  
01-01-2009

2008

Metabolic characteristics of human mesenchymal stem cells expanded under normoxic conditions
Pattappa G, A. Lee D, De Bruijn JD
8th World Biomaterials Congress 2008 vol. 1 
01-12-2008
Analysis of process margin in EUV mask repair with nano-machining
Lee S-Y, Kim G-B, Sim H-S, Lee S-H, Kim H-S, Lee J-H, Seo H-S, Han H-S et al.
Photomask Technology. 
24-10-2008
Phenotypic Analysis of Arabidopsis Mutants: Heavy Metal Stress
Lee D, Schroeder J
Cold Spring Harbor Protocols, Cold Spring Harbor Laboratory vol. 2008 (9), pdb.prot497-pdb.prot497.  
01-09-2008
Monolayer expansion induces an oxidative metabolism and ROS in chondrocytes
Heywood HK, Lee DA
Biochem Bioph Res Co vol. 373 (2), 224-229.  
22-08-2008
Collagen synthesis by tenocytes in fascicles subjected to intermittent cyclic strain
Maeda E, Shelton JC, Bader DL, Lee DA
European Cells and Materials vol. 16 (SUPPL. 3) 
01-07-2008
The effect of oxygen supply on chondrocyte metabolic phenotype during monolayer culture
Heywood HK, Lee DA
European Cells and Materials vol. 16 (SUPPL. 3) 
01-07-2008
Signal transduction pathways involving p38 MAPK, JNK, NFκB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1β and dynamic compression
Chowdhury TT, Salter DM, Bader DL, Lee DA
Inflammation Research, Springer Science and Business Media Llc vol. 57 (7), 306-313.  
12-06-2008
Advantages, Disadvantages, and Uses of Generalized Activity Networks for Schedule Estimation
Hughes D, Whitaker Y, Lee D, Eckhause J
Military Operations Research, Military Operations Research Society vol. 13 (3), 27-40.  
01-06-2008
Mechanical loading modulates intracellular calcium signaling in human mesenchymal stem cells
Campbell JJ, Bader DL, Lee DA
Journal of Applied Biomaterials & Biomechanics vol. 6 (1), 9-15.  
01-01-2008
Dynamic compression counteracts IL-1 beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs
Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Bader DL, Salter DM, Lee DA
Arthritis Res Ther vol. 10 (2) 
01-01-2008
Dynamic compression influences interleukin-1β-induced nitric oxide and prostaglandin E2 release by articular chondrocytes via alterations in iNOS and COX-2 expression
Chowdhury TT, Akanji OO, Salter DM, Bader DL, Lee DA
Biorheology, Sage Publications vol. 45 (3-4), 257-274.  
01-01-2008
The effects of direct current stimulation on isolated chondrocytes seeded in 3D agarose constructs
Akanji OO, Lee DA, Bader DA
 
01-01-2008
Surgeons carry out first implant of pulmonary human heart valve
Lee DA
Biomedical Materials (MAY) 
01-01-2008

2007

52 REAL-TIME PCR USING MOLECULAR BEACONS TO DETECT INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS SUBJECTED TO IL-1β AND DYNAMIC COMPRESSION
Chowdhury TT, Akanji OO, Arghandawi S, Salter DM, Bader DL, Lee DA
Osteoarthritis and Cartilage, Elsevier Bv vol. 15, C42-C43.  
01-12-2007
Predicting protein function from sequence and structure
Lee D, Redfern O, Orengo C
Nature Reviews Molecular Cell Biology, Springer Science and Business Media Llc vol. 8 (12), 995-1005.  
01-12-2007
Root contact during insertion of miniscrews for orthodontic anchorage increases the failure rate: an animal study
Chen Y, Chang H, Chen Y, Lee D, Chiang H, Jane Yao C
Clinical Oral Implants Research, Wiley vol. 19 (1), 99-106.  
23-10-2007
Time dependence of cyclic tensile strain on collagen production in tendon fascicles.
Maeda E, Shelton JC, Bader DL, Lee DA
Biochem Biophys Res Commun vol. 362 (2), 399-404.  
19-10-2007
Repairing 45 nm node defects through nano-machining
White R, Dinsdale A, Robinson T, Brinkley D, Csuy J, Lee D
27th Annual BACUS Symposium on Photomask Technology. 
05-10-2007
Gene expressions in tendon fascicles subjected to cyclic tensile strain
Maeda E, Shelton JC, Bader DL, Lee DA
 
01-07-2007
Development of an immunoassay for determination of adsorbed fibronectin levels on bio-functionalised substrates
Heywood HK, Lee DA
 
01-01-2007
Mechanical loading modulates calcium signalling within mesenchymal stem cells
Campbell JJ, Bader DL, Lee DA
 
01-01-2007
Mesenchymal stem cells maintain a glycolytic metabolism under normoxic conditions
Pattappa G, De Bruijn JD, Lee DA
 
01-01-2007
The development and characterisation of chondrocyte-seeded gradient hydrogel constructs for cartilage tissue engineering
Mcleod R, Pattappa G, Irianto J, Knight MM, Lee DA
 
01-01-2007
Dynamic compression counteracts IL-1βb induced iNOS and COX-2 expression in chondrocytes cultured in agarose constructs
Chowdhury TT, Akanji OO, Arghandawi, Salter DM, Bader DL, Lee DA
 
01-01-2007
A model for studying the influence of mechanical loading on human periosteal stem cells
Bonzani IC, Knight MM, Lee DA, Bader DL, Williams A, Stevens MM
 
01-01-2007
Products: CryoLife wins US patent for foam wound sealant
Lee DA
Biomedical Materials (JULY) 
01-01-2007
Products: CryoLife wins rights to distribute replacement pericardium
Lee DA, Hall J
Biomedical Materials (MAR.) 
01-01-2007
Industry news: CryoLife signs Irish distribution deal with Proxy Biomedical
Lee DA
Biomedical Materials (NOV.), 6-7.  
01-01-2007

2006

Glucose concentration and medium volume influence cell viability and glycosaminoglycan synthesis in chondrocyte-seeded alginate constructs
Heywood HK, Bader DL, Lee DA
 
01-12-2006
New aluminum hydroxide and magnesium hydroxide grades with enhanced flame retardancy
Lee DA, Herbiet R
 
23-11-2006
Glucose Concentration and Medium Volume Influences Cell Viability and Glycosaminoglycan Synthesis in Chondrocyte-Seeded Alginate Constructs
Heywood HK, Bader DL, Lee DA
Tissue Engineering, Mary Ann Liebert Inc, 06112005233-06112005233.  
20-11-2006
Self-Assembly of Latex Particles into Proton-Conductive Membranes
Gao J, Yang Y, Lee D, Holdcroft S, Frisken BJ
Macromolecules, American Chemical Society (Acs) vol. 39 (23), 8060-8066.  
17-10-2006
Precise and high-throughput femtopulse laser mask repair of large defects
White R, LeClaire J, Robinson T, Dinsdale A, Bozak R, Lee DA
26th Annual BACUS Symposium on Photomask Technology. 
06-10-2006
Impact of AFM scan artifacts on photolithographic simulation
Robinson T, Lewellen J, Lee DA, Brooker P
26th Annual BACUS Symposium on Photomask Technology. 
06-10-2006
The influence of swelling and matrix degradation on the microstructural integrity of tendon.
Screen HRC, Chhaya VH, Greenwald SE, Bader DL, Lee DA, Shelton JC
Acta Biomater vol. 2 (5), 505-513.  
01-09-2006
Direct current influences Ca 2+ signalling in chondrocytes
Akanji OO, Bader DL, Lee DA
European Cells and Materials vol. 11 (SUPPL.2) 
01-06-2006
Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes
Chowdhury TT, Appleby RN, Salter DM, Bader DA, Lee DA
Biomech Model Mechan vol. 5 (2-3), 192-201.  
01-06-2006
1.3 The quantitative assessment of flexor tendon adhesion – a novel use of confocal microscopy to evaluate local strain, orientation and organisation
BRANFORD O, LEE D, BADER D, GROBBELAAR A
The Journal of Hand Surgery: Journal of The British Society For Surgery of The Hand, Sage Publications vol. 31, 3-3.  
01-06-2006
Femtopulse laser-based mask repair in the DUV wavelength regime
Ghadiali F, Tolani V, Nagpal R, Robinson T, LeClaire J, Bozak R, Lee DA, White R
Photomask and Next Generation Lithography Mask Technology XIII. 
04-05-2006
Application of photolithographic simulation and a mask repair system in a production environment
Robinson T, Lewellen J, Bozak R, Lee DA, Brooker P
Photomask and Next Generation Lithography Mask Technology XIII. 
04-05-2006
Dynamic compressive strain influences chondrogenic gene expression in human mesenchymal stem cells
Campbell JJ, Lee DA, Bader DL
 
01-05-2006
Concentration and M/G ratio influence the physiochemical and mechanical properties of alginate constructs for tissue engineering
Enobakhare B, Bader DI, Lee D
Journal of Applied Biomaterials and Biomechanics vol. 4 (2), 87-96.  
01-05-2006
Ground plans [13]
Lee D
Professional Engineering vol. 19 (6) 
22-03-2006
Chondrocyte Deformation Induces Mitochondrial Distortion and Heterogeneous Intracellular Strain Fields
Knight MM, Bomzon Z, Kimmel E, Sharma AM, Lee DA, Bader DL
Biomechanics and Modeling in Mechanobiology, Springer Science and Business Media Llc vol. 5 (2-3), 180-191.  
07-03-2006
Comprehensive genome analysis of 203 genomes provides structural genomics with new insights into protein family space
Marsden RL
Nucleic Acids Research, Oxford University Press (Oup) vol. 34 (3), 1066-1080.  
06-02-2006
Rate of oxygen consumption by isolated articular chondrocytes is sensitive to medium glucose concentration
Heywood HK, Bader DL, Lee DA
J Cell Physiol vol. 206 (2), 402-410.  
01-02-2006
Exploiting protein structure data to explore the evolution of protein function and biological complexity
Marsden RL, Ranea JAG, Sillero A, Redfern O, Yeats C, Maibaum M, Lee D, Addou S et al.
Philosophical Transactions of The Royal Society B: Biological Sciences, The Royal Society vol. 361 (1467), 425-440.  
01-02-2006
Anti-inflammatory effects of IL-4 and dynamic compression in IL-1 beta stimulated chondrocytes
Chowdhury TT, Bader DL, Lee DA
Biochem Bioph Res Co vol. 339 (1), 241-247.  
06-01-2006
Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose
Knight MM, Toyoda T, Lee DA, Bader DL
J Biomech vol. 39 (8), 1547-1551.  
01-01-2006
Dynamic compression counteracts IL-1 beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL, Lee DA
Biorheology vol. 43 (3-4), 413-429.  
01-01-2006
Chondrocyte Deformation and Mechanotransduction in Cartilage Model Systems(International Workshop 2)
Bader DL, Lee DA, Knight MM
The Proceedings of The Bioengineering Conference Annual Meeting of Bed/Jsme, Japan Society of Mechanical Engineers vol. 2005.18, 2-3.  
01-01-2006
P140 DYNAMIC COMPRESSION COUNTERACTS FIBRONECTIN FRAGMENT INDUCED UPREGULATION OF NITRIC OXIDE
Chowdhury TT, Raveenthiran SP, Bader DL, Lee DA
Osteoarthritis and Cartilage, Elsevier Bv vol. 14, S86-S86.  
01-01-2006
Gene3D: modelling protein structure, function and evolution
Yeats C
Nucleic Acids Research, Oxford University Press (Oup) vol. 34 (90001), D281-D284.  
01-01-2006
Industry news: CryoLife, BioForm sign glue deal
Lee DA, Gridley A
Biomedical Materials (DEC.), 7-8.  
01-01-2006
Products: Spinal implant looks good so far
Lee DA
Biomedical Materials (JUNE), 4-5.  
01-01-2006
Spinal implants: CryoLife's spinal disc repair study completes enrolment
Lee DA
Biomedical Materials (SEP.), 9-10.  
01-01-2006
Government: US law ensures funding for protein hydrogel development
Lee DA
Biomedical Materials (DEC.) 
01-01-2006

2005

Cyclic mechanical conditioning of isolated tendon fascicles results in an upregulation of collagen production
Screen HRC, Bader DL, Shelton JC, Lee DA
Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 193-194.  
01-12-2005
Dynamic compression counteracts IL-1-induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL, Lee DA
Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 251-252.  
01-12-2005
Integrin mediated mechanotransduction in IL-1 stimulated bovine chondrocytes cultured in agarose constructs
Chowdhury TT, Appleby RN, Salter DA, Bader DL, Lee DA
Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 545-546.  
01-12-2005
Dynamic compression activates chondrocyte calcium signaling in a cycle dependent manner involving the release of ATP
Pingguan B, Lee DA, Bader DL, Knight MM
 
01-12-2005
Identification and characterization of deposited fibronectin on biocompatible materials: Comparison of electrospray and wetting methods
Wang MJ, Heywood HK, Bader DL, Paine MD, Stark JPW, Lee DA
Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 439-440.  
01-12-2005
Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles
Pingguan-Murphy B, Lee DA, Bader DL, Knight MM
Arch Biochem Biophys vol. 444 (1), 45-51.  
01-12-2005
Cyclic tensile strain upregulates collagen synthesis in isolated tendon fascicles.
Screen HRC, Shelton JC, Bader DL, Lee DA
Biochem Biophys Res Commun vol. 336 (2), 424-429.  
21-10-2005
Integration of photolithographic simulation and a mask repair system into a single concurrent work cell
Robinson T, Brooker P, Bozak R, Lee DA
Photomask Technology 2005. 
21-10-2005
Mask repair for the 65-nm technology node
Robinson T, Dinsdale A, Bozak R, White R, Lee DA, Roessler K
Photomask Technology 2005. 
21-10-2005
Nutrient utilization by bovine articular chondrocytes: A combined experimental and theoretical approach
Sengers BG, Heywood HK, Lee DA, Oomens CWJ, Bader DL
J Biomech Eng-T Asme vol. 127 (5), 758-766.  
01-10-2005
The influence of noncollagenous matrix components on the micromechanical environment of tendon fascicles.
Screen HRC, Shelton JC, Chhaya VH, Kayser MV, Bader DL, Lee DA
Ann Biomed Eng vol. 33 (8), 1090-1099.  
01-08-2005
Dynamic compression counteracts IL-1β induced INOS and COX-2 activity by human chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL, Lee DA
European Cells and Materials vol. 10 (SUPPL.2) 
01-07-2005
Dynamic compression influences the biochemical response of human mesenchymal stem cells cultured in agarose constructs
Catuogno C, Chowdhury TT, Bader DL, Lee DA
European Cells and Materials vol. 10 (SUPPL.2) 
01-07-2005
Mechanical compression activates chondrocyte Calcium signalling in a cycle dependent Manner Involving the release of ATP
Pingguna B, Lee DA, Bader DL, Knight MM
 
01-07-2005
Perfusion-Enhancement of molecular transport within 3D scaffolds
Eniwumide JO, Lee DA, Bader DL
European Cells and Materials vol. 10 (SUPPL.2) 
01-07-2005
Superficial and deep chondrocyte subpopulations both express the crabtree effect but exhibit differences in oxygen consumption rate
Heywood HK, Bader DL, Lee DA
European Cells and Materials vol. 10 (SUPPL.2) 
01-07-2005
Mechanical conditioning Influences Mesenchymal stem cell chondrogenesis
Campbell JJ, Lee DA, Bader DL
European Cells and Materials vol. 10 (SUPPL.2) 
01-07-2005
Improved cycle time of mask repair by optimizing nanomachining with photolithographic imaging simulation
Brooker P, Robinson T, Lewellen J, Naber B, Bozak R, Lee DA
Photomask and Next Generation Lithography Mask Technology XII. 
28-06-2005
Self-Assembly of Surface-Charged Latex Nanoparticles:  A New Route to the Creation of Continuous Channels for Ion Conduction
Gao J, Lee D, Yang Y, Holdcroft S, Frisken BJ
Macromolecules, American Chemical Society (Acs) vol. 38 (14), 5854-5856.  
15-06-2005
Cyclic tensile strain upregulates collagen production in isolated tendon fascicles
Screen HRC, Shelton JC, Bader DL, Lee DA
 
01-06-2005
The effect of substrate and medium composition on the response of human dermal fibroblasts to cyclic tensile strain in vitro
Baria KE, Bader DL, Screen HRC, Lee DA
 
01-06-2005
British Society for Matrix Biology Autumn Meeting Joint with the UK Tissue & Cell Engineering Society, University of Bristol, UK

International Journal of Experimental Pathology, Wiley vol. 86 (3), a1-a56.  
24-05-2005
Identification and distribution of protein families in 120 completed genomes using Gene3D
Lee D, Grant A, Marsden RL, Orengo C
Proteins: Structure, Function, and Bioinformatics, Wiley vol. 59 (3), 603-615.  
14-03-2005
Mechanical Conditioning of Cell-Seeded Constructs for Soft Tissue Repair — Are Optimisation Strategies Possible?
Bader DL, Lee DA
, Springer Netherlands, 165-192.  
01-01-2005
Glucose metabolism of chondrocytes in tissue-engineered alginate constructs
Heywood HK, Bader DL, Lee DA
 
01-01-2005
Trimethylamine N-oxide reduces the effects of osmotic stress in EBS keratinocytes
Rugg EL, Al-Rawi H, Lee D, McNeill AM
 
01-01-2005
Compression-induced reorganization of cytoplasmic networks in bovine chondrocytes using mitochondria as markers
Sharma A, Bomzon Z, Lee DA, Kimmel E, Bader DL, Knight MM
 
01-01-2005
Integrin-mediated mechanotransduction in IL-1β-stimulated chondrocytes
Appleby RN, Chowdhury TT, Salter DM, Bader DL, Lee DA
 
01-01-2005
Compression-induced damage in a muscle cell model in vitro
Wang YN, Bouten CVC, Lee DA, Bader DL
P I Mech Eng H vol. 219 (H1), 1-12.  
01-01-2005
Autologous chondrocyte implantation - Culture in a TGF-beta-containing medium enhances the reexpression of a chondrocytic phenotype in passaged human chondrocytes in pellet culture
Goldberg AJ, Lee DA, Bader DL, Bentley G
J Bone Joint Surg Br vol. 87B (1), 128-134.  
01-01-2005

2004

The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis
Pearl F
Nucleic Acids Research, Oxford University Press (Oup) vol. 33 (Database issue), D247-D251.  
17-12-2004
Inspection and repair issues for Step-and-Flash Imprint Lithography templates
Nordquist KJ, Dauksher WJ, Mancini DP, Resnick DJ, Hess HF, Pettibone DW, Adler D, Bertsche K et al.
Photomask Technology. 
06-12-2004
Delusional discourse: An investigation comparing the spontaneous causal attributions of paranoid and non‐paranoid individuals
Lee DA, Randall F, Beattie G, Bentall RP
Psychology and Psychotherapy: Theory, Research and Practice, Wiley vol. 77 (4), 525-540.  
01-12-2004
Local Strain Measurement within Tendon
Bader DL, Shelton JC, Lee DA, SCREEN HRC
Strain vol. 40 (4), 157-163.  
01-11-2004
Repair of step and flash imprint lithography templates
Dauksher WJ, Nordquist KJ, Le NV, Gehoski KA, Mancini DP, Resnick DJ, Casoose L, Bozak R et al.
 
01-11-2004
Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain
Bryant SJ, Anseth KS, Lee DA, Bader DL
J Orthopaed Res vol. 22 (5), 1143-1149.  
01-09-2004
Cellular utilization determines viability and matrix distribution profiles in chondrocyte-seeded alginate constructs
Heywood HK, Sembi PK, Lee DA, Bader DL
Tissue Eng vol. 10 (9-10), 1467-1479.  
01-09-2004
Activin Receptor-like Kinase-7 Induces Apoptosis through Activation of MAPKs in a Smad3-dependent Mechanism in Hepatoma Cells
Kim B-C, van Gelder H, Kim TA, Lee H-J, Baik KG, Chun HH, Lee DA, Choi KS et al.
Journal of Biological Chemistry, Elsevier Bv vol. 279 (27), 28458-28465.  
01-07-2004
Integrin-mediated mechanotransduction processes in TGF beta-stimulated monolayer-expanded chondrocytes
Chowdhury TT, Salter DM, Bader DL, Lee DA
Biochem Bioph Res Co vol. 318 (4), 873-881.  
11-06-2004
Debt crisis looms [10]
Lee D
Professional Engineering vol. 17 (8) 
28-04-2004
Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels
Bryant SJ, Chowdhury TT, Lee DA, Bader DL, Anseth KS
Ann Biomed Eng vol. 32 (3), 407-417.  
01-03-2004
Cyclic preconditioning mediates chondrocytes calcium signaling in unstrained and compressed agarose constructs.
Knight MM, Hibbs K, Roberts SR, LEE DA, Bader DL
50th Annual Meeting of the Orthopaedic Research Society. 
01-01-2004
Non-invasive monitoring of molecular diffusion in neo-cartilage using FRAP technique.
Heywood HK, DeRosa E, LEE DA, Bader DL, Netti P
50th Annual Meeting of the Orthopaedic Research Society. 
01-01-2004
Extracellular matrix influences the response of chondrocytes to dynamic compression
LEE DA, van Osch G, Verhaar JAN, Mandl EW, van der Linden JC, van der Breevaart Bravenboer J, Weinans H
Trans. Orthop.Rev. Soc vol. 29, 839-839.  
01-01-2004
Dynamic compression counteracts IL-1β-induced iNOS and COX-2 activity in human chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL, Lee DA
 
01-01-2004
Heterogeneity of deformation of cytoplasmic networks in compressed chondrocytes.
Knight MM, Bonzom Z, Sharma AM, LEE DA, Kimmel E, Bader DL
50th Annual Meeting of the Orthopaedic Research Society. 
01-01-2004
Glucose depletion induces an upregulation of oxygen utilisation by chondrocytes.
Heywood HK, Bader DL, Bongers M, LEE DA
50th Annual Meeting of the Orthopaedic Research Society. 
01-01-2004
Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes
Chowdhury TT, Appleby RN, Salter DM, Bader DL, Lee DA
 
01-01-2004
An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties.
Screen HRC, Lee DA, Bader DL, Shelton JC
Proc Inst Mech Eng H vol. 218 (2), 109-119.  
01-01-2004
alpha 5 beta 1 integrin mediates mechanotransduction processes in TGF-beta stimulated human chondrocytes seeded in agarose constructs and subjected to dynamic compression.
Chowdhry TT, Salter DM, Bader DL, LEE DA
50th Annual Meeting of the Orthopaedic Research Society. 
01-01-2004
Passage in monolayer influences the response of chondrocytes to dynamic compression
Wiseman M, Bader DL, Reisler T, Lee DA
Biorheology vol. 41 (3-4), 283-298.  
01-01-2004
Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage
Holloway I, Kayser M, Lee DA, Bader DL, Bentley G, Knight MM
Osteoarthr Cartilage vol. 12 (1), 17-24.  
01-01-2004
Mechanical Loading of Chondrocytes Embedded in 3D Constructs
Lee DA, Knight MM
In Cartilage and Osteoarthritis, Springer Nature 307-324.  
01-01-2004
Combined anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated bovine chondrocytes cultured in agarose constructs.
Chowdhury TT, Bader DL, LEE DA
50th Annual Meeting of the Orthopaedic Research Society. 
01-01-2004
A structural perspective on genome evolution
Lee D, Grant A, Sillitoe I, Dibley M, Ranea JG, Orengo C
the eighth annual international conference 27 Mar 2004 - 31 Mar 2004. 
01-01-2004

Grant A, Lee D, Orengo C
Genome Biology, Springer Science and Business Media Llc vol. 5 (5), 107-107.  
01-01-2004
EyeSite: a semi-automated database of protein families in the eye
Lee DA
Nucleic Acids Research, Oxford University Press (Oup) vol. 32 (90001), 148D-152.  
01-01-2004

2003

Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression.
Chowdhury TT, Bader DL, Shelton JC, Lee DA
Arch Biochem Biophys vol. 417 (1), 105-111.  
01-09-2003
Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE(2) by superficial zone chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL, Lee DA
Osteoarthr Cartilage vol. 11 (9), 688-696.  
01-09-2003
Trimethylaminuria and a humanFMO3 mutation database
Hernandez D, Addou S, Lee D, Orengo C, Shephard EA, Phillips IR
Human Mutation, Hindawi Limited vol. 22 (3), 209-213.  
18-08-2003
Influence of external uniaxial cyclic strain on oriented fibroblast-seeded collagen gels.
Berry CC, Shelton JC, Bader DL, Lee DA
Tissue Eng vol. 9 (4), 613-624.  
01-08-2003
Dynamic compressive strain inhibits nitric oxide synthesis by equine chondrocytes isolated from different areas of the cartilage surface
Wiseman M, Henson F, Lee DA, Bader DL
Equine Vet J vol. 35 (5), 451-456.  
01-07-2003
A structural perspective on genome evolution
Lee D, Grant A, Buchan D, Orengo C
Current Opinion in Structural Biology, Elsevier Bv vol. 13 (3), 359-369.  
01-06-2003
Live cell imaging using confocal microscopy induces intracellular calcium transients and cell death
Knight MM, Roberts SR, Lee DA, Bader DL
Am J Physiol-Cell Ph vol. 284 (4), C1083-C1089.  
01-04-2003
Expansion of chondrocytes for tissue engineering in alginate beads enhances chondrocytic phenotype compared to conventional monolayer techniques
Lee DA, Reisler T, Bader DL
Acta Orthop Scand vol. 74 (1), 6-15.  
01-02-2003
Mechanical conditioning influences the metabolic response of cell-seeded constructs.
Shelton JC, Bader DL, Lee DA
Cells Tissues Organs vol. 175 (3), 140-150.  
01-01-2003
alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta3-stimulated human chondrocytes seeded in agarose constructs and subjected to dynamic compression.
Chowdhury TT, LEE DA, Salter DM, Shelton JC, Bader DL
ETES. 
01-01-2003
Dermal fibroblasts respond to mechanical conditioning in a strain profile dependent manner.
Berry CC, Cacou C, Lee DA, Bader DL, Shelton JC
Biorheology vol. 40 (1-3), 337-345.  
01-01-2003
Development of a technique to determine strains in tendons using the cell nuclei.
Screen HRC, Lee DA, Bader DL, Shelton JC
Biorheology vol. 40 (1-3), 361-368.  
01-01-2003
alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta-stimulated human chondrocyte / agarose constructs and subjected to dynamic compression.
Chowdhury TT, LEE DA, Salter DM, Shelton JC, Bader DL
Osteoarthritis Cartilage vol. 11 (Suppl 1), S2-S3.  
01-01-2003
Control of mechanotrasduction processes in dynamically stimulated human and bovine chondrocytes cultured in agarose constructs.
Chowdhury TT, Shelton JC, Bader DL, LEE DA
Internat. J. Artificial Organs vol. 26 (9), 858-858.  
01-01-2003
The effects on non-collagenous matrix components on tendon fascicle micromechanics.
SCREEN HRC, Shelton JC, Bader DL, Lee DA
49th Annual Meeting of the Orthopaedic Research Society. 
01-01-2003
Experimental and theoretical analysis of glucose dependent oxygen utilization by bovine articular chondrocytes
LEE DA, Heywood HK, Baaijens FPT, Oomens CWJ, Sengers BG
Internat. J. Artificial Organs vol. 26, 875-875.  
01-01-2003

2002

The influence of uniaxial cyclic strain on orientated fibroblast seeded collagen gels
Berry CC, Shelton JC, Bader DL, Lee DA
Third Smith and Nephew International Symposium Translating Tissue Engineering Into Products 
01-12-2002
Mechanical strain and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose
Knight MM, Toyoda T, Bader DL, Lee DA
 
01-12-2002
Light-induced calcium signalling in chondrocytes
Knight MM, Roberts SR, Lee DA, Bader DL
 
01-12-2002
The design of bioreactor systems for cartilage tissue engineering
Lee DA
Third Smith and Nephew International Symposium Translating Tissue Engineering Into Products 
01-12-2002
Monitoring neo-cartilage formation in cell seeded alginate constructs of clinically relevant dimensions
Heywood HK, Lee DA, Bader DL
 
01-12-2002
Changes in cell morphology and cytoskeletal organisation in osteoarthric cartilage
Holloway I, Knight MM, Lee DA, Bader DL, Bentley G
 
01-09-2002
An in Vitro Investigation of Cartilage Mechanotransduction
Lee DA, Chowdhury TT, Roberts SR, Knight MM, Bader DL
 
01-07-2002
The origin of [Fe ii] emission in NGC 4151
Turner JEH, Allington-Smith J, Chapman S, Content R, Done C, Haynes R, Lee D, Morris S
Monthly Notices of The Royal Astronomical Society, Oxford University Press (Oup) vol. 331 (2), 284-292.  
01-03-2002
Cell and nucleus deformation in compressed chondrocyte-alginate constructs: temporal changes and calculation of cell modulus
Knight MM, Bravenboer JVDB, Lee DA, van Osch GJVM, Weinans H, Bader DL
Bba-Gen Subjects vol. 1570 (1), 1-8.  
15-02-2002
The CATH extended protein‐family database: Providing structural annotations for genome sequences
Pearl FMG, Lee D, Bray JE, Buchan DWA, Shepherd AJ, Orengo CA
Protein Science, Wiley vol. 11 (2), 233-244.  
01-02-2002
The strain behaviour of tendon under tensile load, using cell nuclei as strain markers.
SCREEN HRC, Lee DA, Bader DL, Shelton JC
48th Annual Meeting of the Orthopaedic Research Society. 
01-01-2002
Light-induced calcium signalling in chondrocytes.
Knight MM, Roberts SR, LEE DA, Bader DL
TCES 2002 Annual meeting of the UK Tissue and Cell Engineering Society University of Glasgow, Scotland 19 Sep 2002 - 20 Sep 2002. 
01-01-2002
Mechanical strain and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose.
Knight MM, Toyoda T, LEE DA, Bader DL
48th Annual Meeting of the Orthopaedic Research Society. 
01-01-2002
Non-collagenous matrix components influence the micromechanical environment of tenocytes within tendon fascicles subjected to tensile strain.
Bader DL, Shelton JC, Lee DA, SCREEN HRC
Eur. Cells Mat. vol. 4:S1, 41-42.  
01-01-2002
Characterisation of cell morphology, cytoskeletal organization and apoptosis in human osteoarthritic cartilage.
Holloway I, Knight MM, LEE DA, Bader DL, Bentley G
48th Annual Meeting of the Orthopaedic Research Society. 
01-01-2002
Deformation properties of articular chondrocytes: A critique of three separate techniques
Bader DL, Ohashi T, Knight MM, Lee DA, Sato M
 
01-01-2002
The CATH protein family database: A resource for structural and functional annotation of genomes
Orengo CA, Bray JE, Buchan DWA, Harrison A, Lee D, Pearl FMG, Sillitoe I, Todd AE et al.
 
01-01-2002

2001

Characterization of Lenslet Arrays for Astronomical Spectroscopy
Lee D, Haynes R, Ren D, Allington‐Smith J
Publications of The Astronomical Society of The Pacific, Iop Publishing vol. 113 (789), 1406-1419.  
01-11-2001
Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine (2000)
Bader D, Lee D
Medical Engineering &Amp; Physics, Elsevier Bv vol. 23 (8), 597-597.  
01-10-2001
Properties of optical fibres at cryogenic temperatures
Lee D, Haynes R, Skeen DJ
Monthly Notices of The Royal Astronomical Society, Oxford University Press (Oup) vol. 326 (2), 774-780.  
01-09-2001
Effects of Tissue Transglutaminase on Retinoic Acid-induced Cellular Differentiation and Protection against Apoptosis
Antonyak MA, Singh US, Lee DA, Boehm JE, Combs C, Zgola MM, Page RL, Cerione RA
Journal of Biological Chemistry, Elsevier Bv vol. 276 (36), 33582-33587.  
01-09-2001
The early-type galaxy population in Abell 2218
Ziegler BL, Bower RG, Smail I, Davies RL, Lee D
Monthly Notices of The Royal Astronomical Society, Oxford University Press (Oup) vol. 325 (4), 1571-1590.  
21-08-2001
Dynamic compression inhibits the synthesis of nitric oxide and PGE(2) by IL-1 beta-stimulated chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL, Lee DA
Biochem Bioph Res Co vol. 285 (5), 1168-1174.  
03-08-2001
Chondrocyte deformation within mechanically and enzymatically extracted chondrons compressed in agarose
Knight MM, Ross JM, Sherwin AF, Lee DA, Bader DL, Poole CA
Bba-Gen Subjects vol. 1526 (2), 141-146.  
03-05-2001
Temporal changes in cytoskeletal organisation within isolated chondrocytes quantified using a novel image analysis technique
Knight MM, Idowu BD, Lee DA, Bader DL
Med Biol Eng Comput vol. 39 (3), 397-404.  
01-05-2001
Mechanical compression influences intracellular Ca2+ signaling in chondrocytes seeded in agarose constructs
Roberts SR, Knight MM, Lee DA, Bader DL
J Appl Physiol vol. 90 (4), 1385-1391.  
01-04-2001
Compressive Deformation and Damage of Muscle Cell Subpopulations in a Model System
Bouten CVC, Knight MM, Lee DA, Bader DL
Annals of Biomedical Engineering, Springer Science and Business Media Llc vol. 29 (2), 153-163.  
01-02-2001
Compressive deformation and damage of muscle cell subpopulations in a model system
Bouten CVC, Knight MM, Lee DA, Bader DL
Ann Biomed Eng vol. 29 (2), 153-163.  
01-02-2001
Embryonic stem cells: scientific possibilities, ethical considerations, and regulation in the UK
Lee DA
Interdisciplinary Science Reviews, Sage Publications vol. 26 (2), 112-124.  
01-02-2001
Temporal changes in cell and nucleus deformation in isolated chondrocytes compressed in alginate scaffolds.
Knight MM, van de Breevaart Brevenboer J, van Osch G, Weinans H, LEE DA, Bader DL
47th Annual Meeting, Orthopaedic Research Society San Francisco, California 25 Feb 2001 - 28 Feb 2001. 
01-01-2001
Dynamic compression influences the synthesis of nitric oxide by IL-1beta stimulated chondrocyte sub-populations cultured in agarose constructs.
Chowdhury T, Bader DL, LEE DA
47th Annual Meeting, Orthopaedic Research Society San Francisco, California 25 Feb 2001 - 28 Feb 2001. 
01-01-2001
Mechanical compression influences cytoskeletal oragnisation within chondrocytes seeded in agarose constructs.
LEE DA, Idowu BD, Knight MM, Bader DL
47th Annual Meeting, Orthopaedic Research Society San Francisco, California 25 Feb 2001 - 28 Feb 2001. 
01-01-2001
Physiochemical, biochemical and mechanical characterisation of chondrocyte-alginate constructs.
Enobakhare B, Bader DL, LEE DA
47th Annual Meeting, Orthopaedic Research Society San Francisco, California 25 Feb 2001 - 28 Feb 2001. 
01-01-2001
VIDA: a virus database system for the organization of animal virus genome open reading frames
Alba MM
Nucleic Acids Research, Oxford University Press (Oup) vol. 29 (1), 133-136.  
01-01-2001
A rapid classification protocol for the CATH Domain Database to support structural genomics
Pearl FMG
Nucleic Acids Research, Oxford University Press (Oup) vol. 29 (1), 223-227.  
01-01-2001

2000

Fibre developments at the Anglo-Australian Observatory for SPIRAL and AUSTRALIS
Lee D, Taylor K
 
03-12-2000
Characterisation of cooled infrared fibres for the Gemini IRMOS
Haynes R, Baldry IK, Taylor K, Lee D
 
03-12-2000
Biological response of cyclic strain on developed cell seeded collagen gel model
Berry CC, Cacou C, Shelton JC, Bader DL, Lee DA
Second Smith and Nephew International Symposium Tissue Engineering 2000 Advances in Tissue Engineering Biomaterials and Cell Sig 
01-12-2000
Intracellular - CA2+ signalling in compressed chondrocyte agarose constructs
Roberts SR, Knight MM, Lee DA, Bader DL
 
01-12-2000
Compression induced cell and nucleus deformation in chondrocyte-alginate constructs
Knight MM, Van De Breevaart Bravenboer J, Bader DL, Lee DA
 
01-12-2000
Physiochemical, biochemical and mechanical characterisation of chondrocyte-alginate constructs
Enobakhare BO, Bader DL, Lee DA
Second Smith and Nephew International Symposium Tissue Engineering 2000 Advances in Tissue Engineering Biomaterials and Cell Sig 
01-12-2000
Dynamic compression inhibits the synthesis of nitric oxide by IL-1β stimulated chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL, Lee DA
Second Smith and Nephew International Symposium Tissue Engineering 2000 Advances in Tissue Engineering Biomaterials and Cell Sig 
01-12-2000
A system for monitoring the response of uniaxial strain on cell seeded collagen gels
Cacou C, Palmer D, Lee DA, Bader DL, Shelton JC
Med Eng Phys vol. 22 (5), 327-333.  
01-06-2000
Confocal analysis of cytoskeletal organisation within isolated chondrocyte sub-populations cultured in agarose
Idowu BD, Knight MM, Bader DL, Lee DA
Histochem J vol. 32 (3), 165-174.  
01-03-2000
An experimental investigation of immersed gratings
Lee D, Allington-Smith JR
Monthly Notices of The Royal Astronomical Society, Oxford University Press (Oup) vol. 312 (1), 57-69.  
11-02-2000
Intracellular calcium signalling in compressed chondrocyte agarose constructs
Roberts SR, Knight MM, Lee DA, Bader DL
 
01-01-2000
Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels
Lee DA, Knight MM, Bolton JF, Idowu BD, Kayser MV, Bader DL
J Biomech vol. 33 (1), 81-95.  
01-01-2000
The influence of mechanical loading on isolated chondrocytes seeded in agarose constructs
Lee DA, Noguchi T, Frean SP, Lees P, Bader DL
Biorheology vol. 37 (1-2), 149-161.  
01-01-2000
Assigning genomic sequences to CATH
Pearl FMG
Nucleic Acids Research, Oxford University Press (Oup) vol. 28 (1), 277-282.  
01-01-2000
Structure – Properties of Soft Tissues Articular Cartilage
Bader D, Lee D
In Pergamon Materials Series, Elsevier 75-103.  
01-01-2000

1999

Transcriptional repression of the transforming growth factor-β type I receptor gene by DNA methylation results in the development of TGF-β resistance in human gastric cancer
Kang SH, Bang Y-J, Im Y-H, Yang H-K, Lee DA, Lee HY, Lee HS, Kim NK et al.
Oncogene, Springer Science and Business Media Llc vol. 18 (51), 7280-7286.  
02-12-1999
Models of government regulation of privatized transit systems in five Latin American cities
Lee DA
Transportation Quarterly vol. 53 (1), 21-39.  
01-12-1999
Multiple‐Object and Integral Field Near‐Infrared Spectroscopy Using Fibers
Haynes R, Lee D, Allington‐Smith J, Content R, Dodsworth G, Lewis I, Sharples R, Turner J et al.
Publications of The Astronomical Society of The Pacific, Iop Publishing vol. 111 (765), 1451-1468.  
01-11-1999
A COMPARATIVE STUDY OF VARIOUS ASSAYS FOR IN VITRO BIOCOMPATIBILITY ASSESSMENT OF EXPERIMENTAL ZIRCONIA
Huang J, Hing KA, Best SM, Lee DA, Silvio LD, Bonfield W
Proceedings of the 12th International Symposium on Ceramics in Medicine. 
01-10-1999
The effects of storage temperature on the composition, metabolism and biomechanical properties of human articular cartilage
White AET, Bentley G, Stephens MD, Bader DL, Giddins GEB, Lee DA
The Knee, Elsevier Bv vol. 6 (3), 197-205.  
01-08-1999
Introducing Fare Simplification and New Convenience Fares at Connecticut Transit
Lee DA
Transportation Research Record: Journal of The Transportation Research Board, Sage Publications vol. 1669 (1), 109-112.  
01-01-1999

1998

A Tour through through
Lee D
Journal of English Linguistics, Sage Publications vol. 26 (4), 333-351.  
01-12-1998
TEIFU: A thousand element integral field unit for the WHT fed by the ELECTRA AO system
Haynes R, Doei AP, Content R, Allington-Smith J, Lee D
 
01-12-1998
Measurement of the deformation of isolated chondrocytes in agarose subjected to cyclic compression
Knight MM, Ghori SA, Lee DA, Bader DL
Med Eng Phys vol. 20 (9), 684-688.  
01-11-1998
Response of chondrocyte subpopulations cultured within unloaded and loaded agarose
Lee DA, Noguchi T, Knight MM, O'Donnell L, Bentley G, Bader DL
J Orthop Res vol. 16 (6), 726-733.  
01-11-1998
The influence of elaborated pericellular matrix on the deformation of isolated articular chondrocytes cultured in agarose
Knight MM, Lee DA, Bader DL
Bba-Mol Cell Res vol. 1405 (1-3), 67-77.  
21-10-1998
Dynamic Mechanical Compression Influences Nitric Oxide Production by Articular Chondrocytes Seeded in Agarose
Lee DA, Frean SP, Lees P, Bader DL
Biochemical and Biophysical Research Communications, Elsevier Bv vol. 251 (2), 580-585.  
01-10-1998
SMIRFS-II: multiobject and integral-field near-IR spectroscopy at UKIRT
Haynes R, Content R, Turner JE, Allington-Smith JR, Lee D
Astronomical Telescopes & Instrumentation. 
21-08-1998
<title>Characterization of microlens arrays for integral field spectroscopy</title>
Lee D, Allington-Smith JR, Content R, Haynes R
Astronomical Telescopes & Instrumentation. 
09-07-1998
<title>Gemini multiobject spectrographs</title>
Murowinski RG, Bond T, Crampton D, Davidge TJ, Fletcher JM, Leckie B, Morbey CL, Roberts SC et al.
Astronomical Telescopes & Instrumentation. 
09-07-1998
The pH-Induced Release of Iron from Transferrin Investigated with a Continuum Electrostatic Model
Lee DA, Goodfellow JM
Biophysical Journal, Elsevier Bv vol. 74 (6), 2747-2759.  
01-06-1998
A specific quantitative assay for collagen synthesis by cells seeded in collagen-based biomaterials using sirius red F3B precipitation
LEE DA, ASSOKU E, DOYLE V
Journal of Materials Science: Materials in Medicine, Springer Science and Business Media Llc vol. 9 (1), 47-51.  
01-01-1998
Erratum: Use of polymerase chain reaction to provide prognostic information on human cytomegalovirus disease after liver transplantation. (Journal of Medical Virology 51 (152-158))
Lao WC, Lee D, Burroughs AK, Lanzani G, Rolles K, Emery VC, Griffiths PD
Journal of Medical Virology vol. 54 (1) 
01-01-1998

1997

GMOS: the GEMINI Multiple Object Spectrographs
Davies RL, Allington-Smith JR, Bettess P, Chadwick E, Content R, Dodsworth GN, Haynes R, Lee D et al.
 
01-12-1997
Effect of Normal Synovial Fluid on the Metabolism of Articular Chondrocytes In Vitro
Lee DA, Salih V, Stockton EF, Stanton JS, Bentley G
Clinical Orthopaedics and Related Research, Ovid Technologies (Wolters Kluwer Health) vol. 342, 228???238-228???238.  
01-09-1997
Quantitative Evaluation of the Exploration Strategies of a Mobile Robot
Lee D, Recce M
The International Journal of Robotics Research, Sage Publications vol. 16 (4), 413-447.  
01-08-1997
Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose
Lee DA, Bader DL
Journal of Orthopaedic Research, Wiley vol. 15 (2), 181-188.  
01-03-1997
Prevalence of anti-Vif antibodies in HIV-1 infected individuals assessed using recombinant baculovirus expressedVif protein
O'Neil C, Lee D, Clewley G, Johnson MA, Emery VC
Journal of Medical Virology, Wiley vol. 51 (3), 139-144.  
01-03-1997
Frame conflicts and competing construals in family argument
Lee DA
Journal of Pragmatics, Elsevier Bv vol. 27 (3), 339-360.  
01-03-1997
Use of polymerase chain reaction to provide prognostic information on human cytomegalovirus disease after liver transplantation
Lao WC, Lee D, Burroughs AK, Lanzini G, Rolles K, Emery VC, Griffiths PD
Journal of Medical Virology, Wiley vol. 51 (3), 152-158.  
01-03-1997

1996

Preliminary Results From the Cancer Research Campaign Trial Evaluating Tamoxifen Duration in Women Aged Fifty Years or Older With Breast Cancer

Jnci Journal of The National Cancer Institute, Oxford University Press (Oup) vol. 88 (24), 1834-1839.  
18-12-1996
Quantification of Sulfated Glycosaminoglycans in Chondrocyte/Alginate Cultures, by Use of 1,9-Dimethylmethylene Blue
Enobakhare BO, Bader DL, Lee DA
Analytical Biochemistry, Elsevier Bv vol. 243 (1), 189-191.  
01-12-1996
Specific quantitative assay to determine the rate of collagen synthesis in a collagen gel system
Doyle V, Pearson RG, Lee DA
 
01-12-1996
Reduction of weather-related terminal area delays in the free-flight era
Johnson SC, Rovinsky RB, Chin DK, Kostiuk PF, Lee DA, Hemm RV, Wingrove ER
 
01-12-1996
Novel system for the production of chondrocyte seeded alginate constructs
Enobakhare B, Bader D, Lee DA
 
01-12-1996
Mechanical strain influences the metabolism of chondrocytes cultured in an artificial matrix
Lee DA, Bader DL
 
01-12-1996
Cellular responses to poly-L-lactic acid degradation products
Pearson RG, Lee DA, Doyle V, Bader DL
 
01-12-1996
J. Virol. Methods
Gor D, Lee D, Emery VC
Journal of Virological Methods, Elsevier Bv vol. 62 (2), 185-185.  
01-12-1996
Detection of human cytomegalovirus polymerase chain reaction products using oligonucleotide probes directly conjugated to alkaline phosphatase
Gor D, Lee D, Emery VC
Journal of Virological Methods, Elsevier Bv vol. 61 (1-2), 145-150.  
01-09-1996
An investigation of the growth of human dermal fibroblasts on poly-L-lactic acid in vitro
Doyle V, Pearson R, Lee D, Wolowacz S, Mc Taggart S
Journal of Materials Science: Materials in Medicine, Springer Science and Business Media Llc vol. 7 (6), 381-385.  
01-06-1996
Conformational analysis of pentapeptide sequences matching a proposed recognition motif for lysosomal degradation
Gorinsky B, Laskowski RA, Lee DA, Bomford A
Biochimica Et Biophysica Acta (Bba) - Protein Structure and Molecular Enzymology, Elsevier Bv vol. 1293 (2), 243-253.  
01-04-1996
Implementing a Visioning and Strategic Planning Process at CTTransit
Lee D, Sanders M
Transportation Research Record: Journal of The Transportation Research Board, Sage Publications vol. 1521, 58-61.  
01-01-1996

1995

The development and characterization of anin vitro system to study strain-induced cell deformation in isolated chondrocytes
Lee DA, Bader DL
In Vitro Cellular &Amp; Developmental Biology - Animal, Springer Science and Business Media Llc vol. 31 (11), 828-835.  
01-12-1995

1994

Quantitative evaluation of the exploration strategies of a mobile robot
Lee D, Recce M
 
01-12-1994
Quantitative evaluation of the exploration strategies of an intelligent vehicle
Lee D, Recce M
 
01-12-1994
Proteoglycan depletion alone is not sufficient to stimulate proteoglycan synthesis in cultured bovine cartilage explants
Lee DA, Bentley G, Archer CW
Osteoarthritis and Cartilage, Elsevier Bv vol. 2 (3), 175-185.  
01-09-1994
Characterization of the repair tissue in articular cartilage defects using silver-enhanced colloidal gold immunostaining
Reissis N, Downes S, Kayser M, Lee D, Bentley G
Journal of Materials Science: Materials in Medicine, Springer Science and Business Media Llc vol. 5 (6-7), 402-406.  
01-01-1994

1993

The control of cell division in articular chondrocytes
LEE D, BENTLEY G, ARCHER C
Osteoarthritis and Cartilage, Elsevier Bv vol. 1 (2), 137-145.  
01-04-1993

1991

Categories in the description of just
Lee DA
Lingua, Elsevier Bv vol. 83 (1), 43-66.  
01-01-1991

1990

Effects of ascorbate on myogenesis in micromass culture
Archer CW, Cottrill CP, Lee D
In Vitro Cellular &Amp; Developmental Biology, Springer Science and Business Media Llc vol. 26 (3), 259-264.  
01-03-1990
Digitization of the AT&T worldwide intelligent network
Lee DA
At T Technology vol. 5 (1), 14-19.  
01-01-1990

1989

VLSI package reliability risk due to accelerated environmental testing
Haupert D, Chen FG, Lee D
 
01-12-1989
Relation between the rate of cell movement under agarose and the positioning of cells in heterotypic aggregates
Jones BM, Evans PM, Lee DA
Experimental Cell Research, Elsevier Bv vol. 180 (1), 287-296.  
01-01-1989

1988

INTEGRATED SERVICES DIGITAL NETWORK.
Lee D
British Telecommunications Engineering vol. 7 (pt 2), 2-12.  
01-07-1988
Moth Density and Oviposition Patterns of the European Corn Borer, Ostrinia nubilalis (Lepidoptera: Pyralidae), in Alberta
Lee DA
Environmental Entomology, Oxford University Press (Oup) vol. 17 (2), 220-224.  
01-04-1988

1987

Reproductive patterns of the European corn borer (Ostrinia nubilalis) in Alberta
Lee DA, Spence JR
Canadian Journal of Zoology, Canadian Science Publishing vol. 65 (7), 1733-1740.  
01-07-1987
The semantics of just
Lee D
Journal of Pragmatics, Elsevier Bv vol. 11 (3), 377-398.  
01-06-1987

1985

MECHANICAL CONVEYING SELECTION CONSIDERATIONS.
Lee DA
 
01-01-1985

1984

GUIDELINES FOR SELECTING PNEUMATIC CONVEYING SYSTEMS.
Lee DA
 
01-12-1984

1983

Prevalence and spectrum of asthma in childhood.
Lee DA, Winslow NR, Speight AN, Hey EN
Bmj, Bmj vol. 286 (6373), 1256-1258.  
16-04-1983
Underdiagnosis and undertreatment of asthma in childhood.
Speight AN, Lee DA, Hey EN
Bmj, Bmj vol. 286 (6373), 1253-1256.  
16-04-1983

1981

Sol-Gel Technology Applied to Crystalline Ceramic Nuclear Waste Forms
Angelini P, Bond WD, Caputo AJ, Mack JE, Lackey WJ, Lee DA, Stinton DP
 
01-01-1981

Mechanical Loading of Chondrocytes Embedded in 3D Constructs: In Vitro Methods for Assessment of Morphological and Metabolic Response to Compressive Strain
Lee DA, Knight MM
, Humana Press, 307-324.  
Bioreactor Culture Techniques for Cartilage-Tissue Engineering
Lee DA, Martin I
In Biopolymer Methods in Tissue Engineering, Humana Press 159-170.  

Grants

solid heart iconGrants of specific relevance to Predictive in vitro Models
solid heart iconClock-Chips - Incorporating the Circadian Clock into Organ-on-a-Chip Technology
David Lee and Lei Su
£387,326 BBSRC Biotechnology and Biological Sciences Research Council
01-10-2024 - 30-09-2026
solid heart iconEPSRC Centre for Doctoral Training in Next Generation Organ-on-a-Chip Technology (COaCT)
Hazel Screen, Martin Knight, Thomas Iskratsch, Caroline Roney, Yi Sui, David Lee, Julia Shelton, Zion Tse, John Connelly, Adrian Biddle and Lucy Norling
£7,066,811 Engineering and Physical Sciences Research Council 
Grant Summary

01-07-2024 - 30-09-2032
bullet iconHarmonised IAA grant - Improve and accelerate the impact of QMUL research BBSRC
David Lee and Viji Draviam Sastry
£495,000 BBSRC Biotechnology and Biological Sciences Research Council
01-04-2022 - 31-03-2026
bullet iconHarmonised IAA grant - Improve and accelerate the impact of QMUL research EPSRC
David Lee and Yang Hao
£882,583 EPSRC Engineering and Physical Sciences Research Council
01-04-2022 - 31-03-2026
bullet iconHarmonised IAA grant - Improve and accelerate the impact of QMUL research MRC
Mauro Perretti, Tatjana Crnogorac-Jurcevic and David Lee
£457,000 MRC Medical Research Council
01-04-2022 - 31-03-2026

bullet iconEngineering Circadian Biology into Human Induced Pluripotent Stem Cell Organ-on-a-Chip models
David Lee and Yung-Yao Lin
£201,874 BBSRC Biotechnology and Biological Sciences Research Council
01-02-2022 - 31-01-2025
bullet iconSuper-Resolution Microscopy of live cells in 3D
Viji Draviam Sastry, Conrad Mullineaux, Vidya Darbari, Lakxmi Subramanian, Fabrice Caudron, Richard Pickersgill, Guy Hanke, Alexander Ruban, Peter Thorpe, Christopher Duffy, Jose Martin Duran, John Connelly, Peter McCormick, Paul Chapple, Vardhman Rakyan, Tyson Sharp, Susana Godinho and David Lee
£369,201 BBSRC Biotechnology and Biological Sciences Research Council
01-12-2020 - 31-03-2022
bullet iconDoes the biological clock within cartilage align to diurnal patterns in activity?
David Lee, Hannah Heywood and Martin Knight
£9,954 EPSRC Engineering and Physical Sciences Research Council
01-10-2019 - 31-10-2020
bullet iconMecho-Regulation of Genome Function
David Lee
£436,194 BBSRC Biotechnology and Biological Sciences Research Council
01-01-2017 - 31-12-2019