Prof Yi Sui
Professor of Fluid Mechanics
School of Engineering and Materials Science
Queen Mary University of London
Queen Mary University of London
Research
computational modelling of cell dynamics in flows, microfluidics cell sorting and characterisation, real-time AI algorithms, in-vitro models for drug delivery
Interests
I am interested in sorting cells from patient blood that can be used to build complex in-vitro models. I have expertise in computational modelling of flow and mass transport, and AI-image based ultrahigh-throughput mechanical characterisation and label-free cell sorting. I am interested in using these tools to understand and develop microfluidics-based in-vitro models such as organ-chips.Publications of specific relevance to Predictive in vitro Models
Publications of specific relevance to Predictive in vitro Models2023
Chen S, Cheng Y, Zhao Z, Zhang K, Hao T, Sui Y, Wang W, Zhao J and Li Y (2023). Core–Shell-Structured Electrorheological Fluid with a Polarizability-Tunable Nanocarbon Shell for Enhanced Stimuli-Responsive Activity. American Chemical Society (Acs) Acs Applied Materials & Interfaces vol. 15, (29) 35741-35749. 10.1021/acsami.3c07133Lu RX, Guo ZY, Yu P and Sui Y (2023). Transient deformation of a viscoelastic capsule in a cross-slot microchannel: effects of inertia and membrane viscosity. Cambridge University Press (Cup) Journal of Fluid Mechanics vol. 962, 10.1017/jfm.2023.298Guo Z, Lin T, Jing D, Wang W and Sui Y (2023). A method for real-time mechanical characterisation of microcapsules. Springer Nature Biomechanics and Modeling in Mechanobiology vol. 22, (4) 1209-1220. 10.1007/s10237-023-01712-7Wang Z, Lu R, Wang W, Tian FB, Feng JJ and Sui Y (2023). A computational model for the transit of a cancer cell through a constricted microchannel. Springer Nature Biomechanics and Modeling in Mechanobiology vol. 22, (4) 1129-1143. 10.1007/s10237-023-01705-62022
Sun C, Dong Y, Wei J, Cai M, Liang D, Fu Y, Zhou Y, Sui Y, Wu F, Mikhaylov R, Wang H, Fan F, Xie Z, Stringer M, Yang Z, Wu Z, Tian L and Yang X (2022). Acoustically accelerated neural differentiation of human embryonic stem cells. Elsevier Acta Biomaterialia vol. 151, 333-345. 10.1016/j.actbio.2022.07.041Lin T, Wang Z, Lu RX, Wang W and Sui Y (2022). Characterising Mechanical Properties of Flowing Microcapsules Using a Deep Convolutional Neural Network. Global Science Press Advances in Applied Mathematics and Mechanics vol. 14, (1) 79-100. 10.4208/aamm.oa-2020-0357Shen Y, Kang F, Cheng Y, Zhang K and Sui Y (2022). Numerical and theoretical analysis of fast evaporating sessile droplets with coupled fields. Elsevier International Journal of Thermal Sciences vol. 172, 10.1016/j.ijthermalsci.2021.1072842021
Lu RX, Wang Z, Salsac A-V, Barthès-Biesel D, Wang W and Sui Y (2021). Path selection of a train of spherical capsules in a branched microchannel. Cambridge University Press (Cup) Journal of Fluid Mechanics vol. 923, 10.1017/jfm.2021.571Lin T, Wang Z, Lu R, Wang W and Sui Y (2021). A high-throughput method to characterize membrane viscosity of flowing microcapsules. Aip Publishing Physics of Fluids vol. 33, (1) 10.1063/5.0031640Lin T, Wang Z, Wang W and Sui Y (2021). A neural network-based algorithm for high-throughput characterisation of viscoelastic properties of flowing microcapsules. Royal Society of Chemistry (Rsc) Soft Matter vol. 17, (15) 4027-4039. 10.1039/d0sm02121k2020
Ma J, Wang Z, Young J, Lai JCS, Sui Y and Tian FB (2020). An immersed boundary-lattice Boltzmann method for fluid-structure interaction problems involving viscoelastic fluids and complex geometries. Elsevier Journal of Computational Physics vol. 415, 10.1016/j.jcp.2020.1094872019
Wang F, Contò FP, Naz N, Castrejón-Pita JR, Castrejón-Pita AA, Bailey CG, Wang W, Feng JJ and Sui Y (2019). A fate-alternating transitional regime in contracting liquid filaments. Journal of Fluid Mechanics vol. 860, 640-653. 10.1017/jfm.2018.855Wang Z, Sui Y, Wang W, Barthѐs-Biesel D and Salsac A-V (2019). Path Selection of a Spherical Capsule in a Branched Channel. Computers, Materials and Continua (Tech Science Press) Molecular & Cellular Biomechanics vol. 16, (S2) 42-43. 10.32604/mcb.2019.071482018
Wang Z, Sui Y, Salsac AV, Barthès-Biesel D and Wang W (2018). Path selection of a spherical capsule in a microfluidic branched channel: Towards the design of an enrichment device. Journal of Fluid Mechanics vol. 849, 136-162. 10.1017/jfm.2018.4142017
Xu Y-Q, Jiang Y-Q, Wu J, Sui Y and Tian F-B (2017). Benchmark numerical solutions for two-dimensional fluid–structure interaction involving large displacements with the deforming-spatial-domain/stabilized space–time and immersed boundary–lattice Boltzmann methods. Sage Publications Proceedings of The Institution of Mechanical Engineers Part C Journal of Mechanical Engineering Science vol. 232, (14) 2500-2514. 10.1177/09544062177239422016
Wang Z, Sui Y, Salsac AV, Barthès-Biesel D and Wang W (2016). Motion of a spherical capsule in branched tube flow with finite inertia. Journal of Fluid Mechanics vol. 806, 603-626. 10.1017/jfm.2016.603Tian F-B, Wang W, Wu J and Sui Y (2016). Swimming performance and vorticity structures of a mother-calf pair of fish. Computers & Fluids vol. 124, 1-11. 10.1016/j.compfluid.2015.10.006Grants of specific relevance to Predictive in vitro Models
Multiscale Modelling of Dissolutive WettingSui Y
£179,947 European Commission (01-01-2022 - 31-12-2024)
Fluid dynamics of deformable capsules enclosed in a microdropletSui Y
£12,000 Royal Society (06-12-2021 - 05-12-2023)
Dynamics of microcapsules in inertial two-phase flowsSui Y
£103,316 Royal Society (01-03-2020 - 28-02-2022)
Margination of microcapsules in small arteriesSui Y
EUR200,000 European Commission (06-08-2015 - 05-08-2018)