Dr Sean Carlson
NHS Clinician / Researcher
Barts NHS Trust
Queen Mary University of London
Queen Mary University of London
Research
Inflammatory bowel disease, Fungal immunity, Candida, Crohn's disease, Ulcerative Colitis, Microbiome
Interests
Using in vitro models to assess damage assays for macrophage cultures inoculated with candida albicans strains from IBD patients and health donorsPublications
2026
DOP078 Development of a bioengineered 3D model of gut barrier defence against Candida albicans invasion and inflammasome activation in Crohn’s DiseaseCarlson S, Mathew L, Pardieu C, Hindle S, Khan M, Blowes L, Munro C, Connelly J et al.
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 20 (Supplement_1)
01-01-2026
2025
Clinical Utility and Cost‐Effectiveness of Pretreatment NUDT15 Pharmacogenetic Testing to Prevent Thiopurine‐Induced Myelosuppression: A Genotype‐First Reverse Phenotyping Cohort Study Within the UK NIHR Inflammatory Bowel Disease BioresourceRoberts C, Peters J, Sazonvos A, Goodman N, Sharip M, Smith R, Bishara M, Bewshea C et al.
Alimentary Pharmacology & Therapeutics, Wiley vol. 62 (6), 630-645.
23-06-2025
2024
P145 Phagocyte responses to gut-derived C. albicans are modified in inflammatory bowel diseaseMathew L, Carlson S, Savage M, Pardieu C, Sze N, Munro C, Naglik J, Stagg A et al.
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 18 (Supplement_1), i441-i441.
24-01-2024
2023
Mucosal Immunity to Gut Fungi in Health and Inflammatory Bowel DiseaseCarlson SL, Mathew L, Savage M, Kok K, Lindsay JO, Munro CA, McCarthy NE
Journal of Fungi, Mdpi vol. 9 (11)
14-11-2023
2022
Implications for sequencing of biologic therapy and choice of second anti‐TNF in patients with inflammatory bowel disease: results from the IMmunogenicity to Second Anti‐TNF therapy (IMSAT) therapeutic drug monitoring studyChanchlani N, Lin S, Auth MK, Lee CL, Robbins H, Looi S, Murugesan SV, Riley T et al.
Alimentary Pharmacology & Therapeutics, Wiley vol. 56 (8), 1250-1263.
29-08-2022
Bacterial suppression of intestinal fungi via activation of human gut γδ T-cellsMathew L, Carlson S, Savage M, Pardieu C, O’Brien M, Crawley E, Harrow P, Kaune A-K et al.
In Biorxiv