Annexin A1/FPR2 pathway modulates leukocyte function during Escherichia coli‐induced pneumonia to promote resolution of inflammation and restores lung function
Lara ES, Carvalho AFS, Cardoso C, Zaidan I, Grossi LC, Carneiro FS, Lima EBS, Monteiro AHA, Caixeta RS, Augusto IL, Montuori‐Andrade ACM, Teixeira LCR, Queiroz‐Junior CM, Russo RC, Perretti M, Costa VV, Teixeira MM, Tavares LP and Sousa LP
British Journal of Pharmacology, Wiley 
01-04-2025

Activation of proresolving macrophages in dorsal root ganglia attenuates persistent arthritis pain
Oggero S, Voisin M-B, Picco F, Huerta MÁ, Cecconello C, Burgoyne T, Perretti M and Malcangio M
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 122 (11) 
10-03-2025

Correction: Pessolano et al. Annexin A1 May Induce Pancreatic Cancer Progression as a Key Player of Extracellular Vesicles Effects as Evidenced in the In Vitro MIA PaCa-2 Model System. Int. J. Mol. Sci. 2018, 19, 3878
Pessolano E, Belvedere R, Bizzarro V, Franco P, De Marco I, Porta A, Tosco A, Parente L, Perretti M and Petrella A
International Journal of Molecular Sciences, Mdpi vol. 25 (17) 
29-08-2024

Effects of a pro‐resolving drug in COVID‐19: preclinical studies to a randomized, placebo‐controlled, phase Ib/IIa trial in hospitalized patients
Almeida PRJ, Periard AM, Tana FL, Avila RE, Milhorato LB, Alcantara KMM, Resende CB, Serufo AV, Santos FR, Teixeira DC, Queiroz‐Junior CM, Fonseca TCM, Silva BLV, Costa VV, Souza RP, Perretti M, Jonassen TEN and Teixeira MM
British Journal of Pharmacology, Wiley vol. 181 (23), 4750-4765.  
19-08-2024

Molecular Determinants of Neutrophil Extracellular Vesicles That Drive Cartilage Regeneration in Inflammatory Arthritis
Thomas BL, Montero‐Melendez T, Oggero S, Kaneva MK, Chambers D, Pinto AL, Nerviani A, Lucchesi D, Austin‐Williams S, Hussain MT, Pitzalis C, Allen B, Malcangio M, Dell'Accio F, Norling LV and Perretti M
Arthritis & Rheumatology, Wiley vol. 76 (12), 1705-1718.  
16-08-2024

Internal Medicine Ward with Hematological Skills for the Treatment of Complications Suffered by Hematological Patients on Therapy: Experience of Villa Betania Hospital inRome
Andriani A, Marchetti L, Rossi F, Perretti MA, Raja S and Recine U
Mediterranean Journal of Hematology and Infectious Diseases, Hematology Section, Dept. of Radiological Science and Hematology, Catholic University, Rome, Italy vol. 16 (1), e2024030-e2024030.  
29-02-2024

Addendum: Resolvins suppress tumor growth and enhance cancer therapy
Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR, Schmidt B, Dalli J, Greene ER, Gus-Brautbar Y, Piwowarski J, Mammoto T, Zurakowski D, Perretti M, Sukhatme VP, Kaipainen A, Kieran MW, Huang S and Panigrahy D
Journal of Experimental Medicine, Rockefeller University Press vol. 221 (3) 
31-01-2024

Report from the 2023 workshop on endothelial permeability, edema and inflammation
Vestweber D, Claesson-Welsh L, McDonald DM, Williams T, Schwartz MA, Scallan J, Gavins FNE, van Buul J, Gamble J, Vadas M, Annex BH, Messe SR, Perretti M, André H, Ferrara N, Hla T, Nourshargh S and Simons M
Nature Cardiovascular Research, Springer Nature vol. 2 (12), 1120-1124.  
01-12-2023

A meta-analysis of genome-wide association studies of childhood wheezing phenotypes identifies ANXA1 as a susceptibility locus for persistent wheezing
Granell R, Curtin JA, Haider S, Kitaba NT, Mathie SA, Gregory LG, Yates LL, Tutino M, Hankinson J, Perretti M, Vonk JM, Arshad HS, Cullinan P, Fontanella S, Roberts GC, Koppelman GH, Simpson A, Turner SW, Murray CS, Lloyd CM, Holloway JW and Custovic A
Elife, Elife vol. 12 
25-05-2023

Formyl Peptide Receptor Type 2 Deficiency in Myeloid Cells Amplifies Sepsis-Induced Cardiac Dysfunction
Chen J, Austin-Williams S, O'Riordan CE, Claria-Ribas P, Sugimoto MA, Norling LV, Thiemermann C and Perretti M
Journal of Innate Immunity, Karger Publishers vol. 15 (1), 548-561.  
01-01-2023

Resolution pharmacology − A fresh approach to the clinical management of human inflammatory diseases
Perretti M and Subramanian M
Seminars in Immunology, Elsevier vol. 65 
22-12-2022

Placental Inflammation Leads to Abnormal Embryonic Heart Development
Ward EJ, Bert S, Fanti S, Malone KM, Maughan RT, Gkantsinikoudi C, Prin F, Volpato LK, Piovezan AP, Graham GJ, Dufton NP, Perretti M, Marelli-Berg FM and Nadkarni S
Circulation, Wolters Kluwer vol. 147 (12), 956-972.  
09-12-2022

Pro-resolving and anti-arthritic properties of the MC1 selective agonist PL8177
Garrido-Mesa J, Thomas BL, Dodd J, Spana C, Perretti M and Montero-Melendez T
Frontiers in Immunology, Frontiers vol. 13 
24-11-2022

Neutrophil‐T cell crosstalk and the control of the host inflammatory response
Bert S, Nadkarni S and Perretti M
Immunological Reviews, Wiley vol. 314 (1), 36-49.  
03-11-2022

Resolution Pharmacology: Focus on Pro-Resolving Annexin A1 and Lipid Mediators for Therapeutic Innovation in Inflammation
Perretti M and Dalli J
The Annual Review of Pharmacology and Toxicology, Annual Reviews vol. 63 (1), 449-469.  
23-09-2022

Dorsal root ganglia CX3CR1 expressing monocytes/macrophages contribute to arthritis pain
Oggero S, Cecconello C, Silva R, Zeboudj L, Sideris-Lampretsas G, Perretti M and Malcangio M
Brain Behavior and Immunity, Elsevier vol. 106, 289-306.  
14-09-2022

Annexin A1-FPR2/ALX Signaling Axis Regulates Acute Inflammation during Chikungunya Virus Infection
de Araújo S, de Melo Costa VR, Santos FM, de Sousa CDF, Moreira TP, Gonçalves MR, Félix FB, Queiroz-Junior CM, Campolina-Silva GH, Nogueira ML, Sugimoto MA, Bonilha CS, Perretti M, Souza DG, Costa VV and Teixeira MM
Cells, Mdpi vol. 11 (17) 
31-08-2022

Formylpeptide receptor 2: Nomenclature, structure, signalling and translational perspectives: IUPHAR review 35
Qin CX, Norling LV, Vecchio EA, Brennan EP, May LT, Wootten D, Godson C, Perretti M and Ritchie RH
British Journal of Pharmacology, Wiley vol. 179 (19), 4617-4639.  
29-07-2022

Role of plasma extracellular vesicles in prediction of cardiovascular risk and alterations in response to statin therapy in hypertensive patients
Oggero S, Godec T, van Gorp R, Pinto AL, Schurgers LJ, Reutelingsperger C, Sever P, Norling LV, Perretti M and Gupta A
Journal of Hypertension, Wolters Kluwer vol. 40 (8), 1522-1529.  
21-06-2022

Immune Cell Plasticity in Inflammation: Insights into Description and Regulation of Immune Cell Phenotypes
Margraf A and Perretti M
Cells, Mdpi vol. 11 (11) 
02-06-2022

Annexin A1 treatment prevents the evolution to fibrosis of experimental nonalcoholic steatohepatitis
Gadipudi LL, Ramavath NN, Provera A, Reutelingsperger C, Albano E, Perretti M and Sutti S
Clinical Science, Portland Press vol. 136 (9), 643-656.  
04-05-2022

Targeting the Annexin A1-FPR2/ALX pathway for host-directed therapy in dengue disease
Costa VV, Sugimoto MA, Hubner J, Bonilha CS, Queiroz-Junior CM, Gonçalves-Pereira MH, Chen J, Gobbetti T, Rodrigues GOL, Bambirra JL, Passos IB, Lopes CEM, Moreira TP, Bonjour K, Melo RC, Oliveira MA, Andrade MVM, Sousa LP, Souza DG, da Costa Santiago H, Perretti M and Teixeira MM
Elife, Elife vol. 11 
16-03-2022

The immunomodulatory effects of social isolation in mice are linked to temperature control
Hamilton A, Rizzo R, Brod S, Ono M, Perretti M, Cooper D and D'Acquisto F
Brain Behavior and Immunity, Elsevier vol. 102, 179-194.  
22-02-2022

Annexin-A1-Derived Peptide Ac2-26 Suppresses Allergic Airway Inflammation and Remodelling in Mice
Ferreira TPT, Guimarães FV, Sá YAPJ, da Silva Ribeiro NB, de Arantes ACS, de Frias Carvalho V, Sousa LP, Perretti M, Martins MA and Rodrigues e Silva PM
Cells, Mdpi vol. 11 (5) 
22-02-2022

Formyl Peptide Receptors and Annexin A1: Complementary Mechanisms to Infliximab in Murine Experimental Colitis and Crohn’s Disease
de Paula-Silva M, da Rocha GHO, Broering MF, Queiroz ML, Sandri S, Loiola RA, Oliani SM, Vieira A, Perretti M and Farsky SHP
Frontiers in Immunology, Frontiers vol. 12 
17-09-2021

Annexin A1 attenuates cardiac diastolic dysfunction in mice with inflammatory arthritis
Chen J, Norling LV, Mesa JG, Silva MDP, Burton SE, Reutelingsperger C, Perretti M and Cooper D
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 118 (38) 
15-09-2021

Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists
Maciuszek M, Ortega-Gomez A, Maas SL, Garrido-Mesa J, Ferraro B, Perretti M, Merritt A, Nicolaes GAF, Soehnlein O and Chapman TM
European Journal of Medicinal Chemistry, Elsevier vol. 226 
02-09-2021

Role of formyl peptide receptor 2 (FPR2) in modulating immune response and heart inflammation in an experimental model of acute and chronic Chagas disease
das Dores Pereira R, Rabelo RAN, Leite PG, Cramer A, Botelho AFM, Cruz JS, Régis WCB, Perretti M, Teixeira MM and Machado FS
Cellular Immunology, Elsevier vol. 369 
29-08-2021

A peptide derived from chaperonin 60.1, IRL201104, inhibits LPS-induced acute lung inflammation
Man F, Nadkarni S, Kanabar V, E-Lacerda RR, Gomes Ferreira S, Federici Canova D, Perretti M, Page CP and Riffo-Vasquez Y
American Journal of Physiology - Lung Cellular and Molecular Physiology, American Physiological Society vol. 321 (5), l803-l813.  
25-08-2021

Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation
Reglero-Real N, Pérez-Gutiérrez L, Yoshimura A, Rolas L, Garrido-Mesa J, Barkaway A, Pickworth C, Saleeb RS, Gonzalez-Nuñez M, Austin-Williams SN, Cooper D, Vázquez-Martínez L, Fu T, De Rossi G, Golding M, Voisin M-B, Boulanger CM, Kubota Y, Muller WA, Tooze SA, Nightingale TD, Collinson L, Perretti M, Aksoy E and Nourshargh S
Immunity, Elsevier vol. 54 (9), 1989-2004.e9.  
06-08-2021

Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions
Coenen DM, Heinzmann ACA, Oggero S, Albers HJ, Nagy M, Hagué P, Kuijpers MJE, Vanderwinden J-M, van der Meer AD, Perretti M, Koenen RR and Cosemans JMEM
Cells, Mdpi vol. 10 (8) 
05-08-2021

Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in COVID-19
Koenis DS, Beegun I, Jouvene CC, Aguirre GA, Souza PR, Gonzalez-Nunez M, Ly L, Pistorius K, Kocher HM, Ricketts W, Thomas G, Perretti M, Alusi G, Pfeffer P and Dalli J
Circulation Research, E54-E71.  
09-07-2021

Mesoglycan connects Syndecan‐4 and VEGFR2 through Annexin A1 and formyl peptide receptors to promote angiogenesis in vitro
Pessolano E, Belvedere R, Novizio N, Filippelli A, Perretti M, Whiteford J and Petrella A
The Febs Journal, Wiley vol. 288 (22), 6428-6446.  
22-06-2021

Asymmetric Synthesis and Biological Screening of Quinoxaline-Containing Synthetic Lipoxin A4 Mimetics (QNX-sLXms)
de Gaetano M, Tighe C, Gahan K, Zanetti A, Chen J, Newson J, Cacace A, Marai M, Gaffney A, Brennan E, Kantharidis P, Cooper ME, Leroy X, Perretti M, Gilroy D, Godson C and Guiry PJ
Journal of Medicinal Chemistry, American Chemical Society (Acs) vol. 64 (13), 9193-9216.  
17-06-2021

WNT3A-loaded exosomes enable cartilage repair
Thomas B, Eldridge S, Nosrati B, Alvarez M, THORUP A-S, Nalesso G, Caxaria S, Barawi A, Nicholson J, Perretti M, Gaston-Massuet C, Pitzalis C, Maloney A, Moore A, Jupp R and Dell'Accio F
Journal of Extracellular Vesicles, Co-Action Publishing 
19-05-2021

Cell barrier function of resident peritoneal macrophages in post-operative adhesions
Ito T, Shintani Y, Fields L, Shiraishi M, Podaru M, Kainuma S, Yamashita K, Kobayashi K, Perretti M, Lewis-McDougall F and Suzuki K
Nature Communications, Springer Nature vol. 12 (1) 
14-04-2021

Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity
Oggero S, de Gaetano M, Marcone S, Fitzsimons S, Pinto AL, Ikramova D, Barry M, Burke D, Montero‐Melendez T, Cooper D, Burgoyne T, Belton O, Norling LV, Brennan EP, Godson C and Perretti M
Journal of Extracellular Vesicles, Wiley vol. 10 (6) 
01-04-2021

Corrigendum to “Activation of Melanocortin Receptors MC1 and MC5 Attenuates Retinal Damage in Experimental Diabetic Retinopathy”
Rossi S, Maisto R, Gesualdo C, Trotta MC, Ferraraccio F, Kaneva MK, Getting SJ, Surace E, Testa F, Simonelli F, Grieco P, Merlino F, Perretti M, D’Amico M and Di Filippo C
Mediators of Inflammation, Hindawi vol. 2021 (1) 
30-03-2021

Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation
Maciuszek M, Ortega-Gomez A, Maas SL, Perretti M, Merritt A, Soehnlein O and Chapman TM
European Journal of Medicinal Chemistry, Elsevier vol. 214 
16-01-2021

Senescence under appraisal: hopes and challenges revisited
Davan-Wetton CSA, Pessolano E, Perretti M and Montero-Melendez T
Cellular and Molecular Life Sciences, Springer Nature vol. 78 (7), 3333-3354.  
13-01-2021

Annexin A1 Released in Extracellular Vesicles by Pancreatic Cancer Cells Activates Components of the Tumor Microenvironment, through Interaction with the Formyl-Peptide Receptors
Novizio N, Belvedere R, Pessolano E, Tosco A, Porta A, Perretti M, Campiglia P, Filippelli A and Petrella A
Cells, Mdpi vol. 9 (12) 
18-12-2020

microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression
Fitzsimons S, Oggero S, Bruen R, McCarthy C, Strowitzki MJ, Mahon NG, Ryan N, Brennan EP, Barry M, Perretti M and Belton O
Frontiers in Immunology, Frontiers vol. 11 
17-12-2020

RETRACTED: Mesoglycan exerts its fibrinolytic effect through the activation of annexin A2
Belvedere R, Morretta E, Pessolano E, Novizio N, Tosco A, Porta A, Whiteford J, Perretti M, Filippelli A, Monti MC and Petrella A
Journal of Cellular Physiology, Wiley vol. 236 (7), 4926-4943.  
07-12-2020

Switching on resolution to treat RA moves closer to reality
Perretti M
Nature Reviews Rheumatology, Springer Nature vol. 17 (2), 73-74.  
30-11-2020

Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid.
Brouwers H, Jónasdóttir HS, Kuipers ME, Kwekkeboom JC, Auger JL, Gonzalez-Torres M, López-Vicario C, Clària J, Freysdottir J, Hardardottir I, Garrido-Mesa J, Norling LV, Perretti M, Huizinga TWJ, Kloppenburg M, Toes REM, Binstadt B, Giera M and Ioan-Facsinay A
The Journal of Immunology, Oxford University Press (Oup) vol. 205 (10), 2840-2849.  
15-11-2020

The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections
Souza PR, Walker ME, Goulding NJ, Dalli J, Perretti M and Norling LV
Frontiers in Immunology, Frontiers Media vol. 11, 573019-573019.  
29-09-2020

Heparan sulfate binds the extracellular Annexin A1 and blocks its effects on pancreatic cancer cells
Belvedere R, Novizio N, Pessolano E, Tosco A, Eletto D, Porta A, Campiglia P, Perretti M, Filippelli A and Petrella A
Biochemical Pharmacology, Elsevier vol. 182 
28-09-2020

Formyl peptide receptor type 2 agonists to kick‐start resolution pharmacology
Perretti M and Godson C
British Journal of Pharmacology, Wiley vol. 177 (20), 4595-4600.  
20-09-2020

The Atlas of Inflammation Resolution (AIR)
Serhan CN, Gupta SK, Perretti M, Godson C, Brennan E, Li Y, Soehnlein O, Shimizu T, Werz O, Chiurchiù V, Azzi A, Dubourdeau M, Gupta SS, Schopohl P, Hoch M, Gjorgevikj D, Khan FM, Brauer D, Tripathi A, Cesnulevicius K, Lescheid D, Schultz M, Särndahl E, Repsilber D, Kruse R, Sala A, Haeggström JZ, Levy BD, Filep JG and Wolkenhauer O
Molecular Aspects of Medicine, Elsevier 
01-08-2020

Annexin A1/Formyl Peptide Receptor Pathway Controls Uterine Receptivity to the Blastocyst
Hebeda CB, Sandri S, Benis CM, de Paula-Silva M, Loiola RA, Reutelingsperger C, Perretti M and Farsky SHP
Cells, Mdpi vol. 9 (5) 
11-05-2020

Imbalance of proresolving lipid mediators in persistent allodynia dissociated from signs of clinical arthritis
Allen BL, Montague-Cardoso K, Simeoli R, Colas RA, Oggero S, Vilar B, McNaughton PA, Dalli J, Perretti M, Sher E and Malcangio M
Pain, Lippincott, Williams & Wilkins 
04-05-2020

H and L Chain Affinity Maturation and/or Fab N-Glycosylation Influence Immunoreactivity toward Neutrophil Extracellular Trap Antigens in Rheumatoid Arthritis Synovial B Cell Clones
Corsiero E, Carlotti E, Jagemann L, Perretti M, Pitzalis C and Bombardieri M
The Journal of Immunology, Oxford University Press (Oup) vol. 204 (9) 
01-05-2020

Proresolving lipid mediators enhance PMN-mediated bacterial clearance
Norling LV and Perretti M
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 117 (17), 9148-9150.  
16-04-2020

Immuno-moodulin: A new anxiogenic factor produced by Annexin-A1 transgenic autoimmune-prone T cells
Piras G, Rattazzi L, Paschalidis N, Oggero S, Berti G, Ono M, Bellia F, D'Addario C, Dell'Osso B, Pariante CM, Perretti M and D'Acquisto F
Brain Behavior and Immunity, Elsevier vol. 87, 689-702.  
29-02-2020

Targeting Extracellular Vesicles to the Arthritic Joint Using a Damaged Cartilage-Specific Antibody
Topping LM, Thomas BL, Rhys HI, Tremoleda JL, Foster M, Seed M, Voisin MB, Vinci C, Law HL, Perretti M, Norling LV, Azevedo HS and Nissim A
Frontiers in Immunology, Frontiers Media vol. 11 
14-02-2020

Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis
Montero Melendez T, Nagano A, Chelala C, Filer A, Buckley CD and Perretti M
Nature Communications, Nature Research (Part of Springer Nature) vol. 11 (1) 
06-02-2020

Annexin A1 drives macrophage skewing towards a resolving phenotype to accelerate the regeneration of muscle injury through AMPK activation
McArthur S, Gobbetti T, Juban G, Desgeorges T, Theret M, Gondin J, Toller-Kawahisa JE, Reutelingsperger CP, Perretti M and Mounier R
Journal of Clinical Investigation, American Society For Clinical Investigation 
04-02-2020

Mesoglycan induces the secretion of microvesicles by keratinocytes able to activate human fibroblasts and endothelial cells: A novel mechanism in skin wound healing
Belvedere R, Pessolano E, Porta A, Tosco A, Parente L, Petrella F, Perretti M and Petrella A
European Journal of Pharmacology, Elsevier vol. 869 
26-12-2019

The Annexin A1/FPR2 pathway controls the inflammatory response and bacterial dissemination in experimental pneumococcal pneumonia
Machado MG, Tavares LP, Souza GVS, Queiroz‐Junior CM, Ascenção FR, Lopes ME, Garcia CC, Menezes GB, Perretti M, Russo RC, Teixeira MM and Sousa LP
The Faseb Journal, Wiley vol. 34 (2), 2749-2764.  
26-12-2019

Endogenous Annexin-A1 Negatively Regulates Mast Cell-Mediated Allergic Reactions
Sinniah A, Yazid S, Bena S, Oliani SM, Perretti M and Flower RJ
Frontiers in Pharmacology, Frontiers vol. 10 
13-11-2019

Extracellular annexin-A1 promotes myeloid/granulocytic differentiation of hematopoietic stem/progenitor cells via the Ca2+/MAPK signalling transduction pathway
Barbosa CMV, Fock RA, Hastreiter AA, Reutelingsperger C, Perretti M, Paredes-Gamero EJ and Farsky SHP
Cell Death Discovery, Springer Nature vol. 5 (1) 
23-09-2019

Annexin A1 Contained in Extracellular Vesicles Promotes the Activation of Keratinocytes by Mesoglycan Effects: An Autocrine Loop Through FPRs
Pessolano E, Belvedere R, Bizzarro V, Franco P, De Marco I, Petrella F, Porta A, Tosco A, Parente L, Perretti M and Petrella A
Cells, Mdpi vol. 8 (7) 
19-07-2019

Plasminogen and the Plasminogen Receptor, Plg-RKT, Regulate Macrophage Phenotypic, and Functional Changes
Vago JP, Sugimoto MA, Lima KM, Negreiros-Lima GL, Baik N, Teixeira MM, Perretti M, Parmer RJ, Miles LA and Sousa LP
Frontiers in Immunology, Frontiers vol. 10 
28-06-2019

Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation
Senchenkova EY, Ansari J, Becker F, Vital SA, Al-Yafeai Z, Sparkenbaugh EM, Pawlinski R, Stokes KY, Carroll JL, Dragoi A-M, Qin CX, Ritchie RH, Sun H, Cuellar-Saenz HH, Rubinstein MR, Han YW, Orr AW, Perretti M, Granger DN and Gavins FNE
Circulation, Wolters Kluwer vol. 140 (4), 319-335.  
03-06-2019

The formyl peptide fMLF primes platelet activation and augments thrombus formation
Salamah MF, Ravishankar D, Vaiyapuri R, Moraes LA, Patel K, Perretti M, Gibbins JM and Vaiyapuri S
Journal of Thrombosis and Haemostasis, Elsevier vol. 17 (7), 1120-1133.  
24-05-2019

Mesoglycan induces keratinocyte activation by triggering syndecan‐4 pathway and the formation of the annexin A1/S100A11 complex
Bizzarro V, Belvedere R, Pessolano E, Parente L, Petrella F, Perretti M and Petrella A
Journal of Cellular Physiology, Wiley vol. 234 (11), 20174-20192.  
08-04-2019

Identification of an activated neutrophil phenotype in polymyalgia rheumatica during steroid treatment: potential involvement of immune cell cross talk
Nadkarni S, Lashin H, Hollywood J, Dasgupta B, Mason JC and Perretti M
Clinical Science, Portland Press vol. 133 (7) 
04-04-2019

Proteomic analysis of neutrophils in ANCA-associated vasculitis reveals a dysregulation in proteinase 3-associated proteins such as annexin-A1 involved in apoptotic cell clearance
Everts-Graber J, Martin KR, Thieblemont N, Mocek J, Roccabianca A, Chafey P, Le Gall M, Tacnet-Delorme P, Reutelingsperger CP, Naccache J-M, Bonnotte B, Karras A, Puéchal X, Guillevin L, Terrier B, Frachet P, Perretti M, Mouthon L and Witko-Sarsat V
Kidney International, Elsevier vol. 96 (2), 397-408.  
04-03-2019

Mediators of the Resolution of the Inflammatory Response
Sugimoto MA, Vago JP, Perretti M and Teixeira MM
Trends in Immunology, Elsevier vol. 40 (3), 212-227.  
13-02-2019

Formyl peptide receptor 1 signalling promotes experimental colitis in mice
Di Paola R, Fusco R, Gugliandolo E, D'Amico R, Cordaro M, Impellizzeri D, Perretti M and Cuzzocrea S
Pharmacological Research, Elsevier vol. 141, 591-601.  
31-01-2019

Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post ischemia/reperfusion injury
VOISIN M, leoni G, WOODFIN A, loumagne L, PATEL N, Di Paola R, Cuzzocrea S, THIEMERMANN C, PERRETTI M and NOURSHARGH S
Journal of Pathology, Wiley vol. 248 (1), 88-102.  
11-01-2019

Annexin A1 May Induce Pancreatic Cancer Progression as a Key Player of Extracellular Vesicles Effects as Evidenced in the In Vitro MIA PaCa-2 Model System
Pessolano E, Belvedere R, Bizzarro V, Franco P, De Marco I, Porta A, Tosco A, Parente L, Perretti M and Petrella A
International Journal of Molecular Sciences, Mdpi vol. 19 (12) 
04-12-2018

Resolution of Inflammation Through the Lipoxin and ALX/FPR2 Receptor Pathway Protects Against Abdominal Aortic Aneurysms
Petri MH, Thul S, Andonova T, Lindquist-Liljeqvist M, Jin H, Skenteris N-T, Arnardottir H, Maegdefessel L, Caidahl K, Perretti M, Roy J and Bäck M
Jacc Basic to Translational Science, Elsevier vol. 3 (6), 719-727.  
01-12-2018

The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation
Salamah MF, Ravishankar D, Kodji X, Moraes LA, Williams HF, Vallance TM, Albadawi DA, Vaiyapuri R, Watson K, Gibbins JM, Brain SD, Perretti M and Vaiyapuri S
Blood Advances, American Society of Hematology vol. 2 (21), 2973-2985.  
09-11-2018

Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A4 mimetics (sLXms)
de Gaetano M, Butler E, Gahan K, Zanetti A, Marai M, Chen J, Cacace A, Hams E, Maingot C, McLoughlin A, Brennan E, Leroy X, Loscher CE, Fallon P, Perretti M, Godson C and Guiry PJ
European Journal of Medicinal Chemistry, Elsevier vol. 162, 80-108.  
23-10-2018

n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis.
Frigerio F, Pasqualini G, Craparotta I, Marchini S, van Vliet EA, Foerch P, Vandenplas C, Leclercq K, Aronica E, Porcu L, Pistorius K, Colas RA, Hansen TV, Perretti M, Kaminski RM, Dalli J and Vezzani A
Brain vol. 141 (11), 3130-3143.  
10-10-2018

Neutrophil wrap
Thomas BL and Perretti M
Nature Nanotechnology, Springer Nature vol. 13 (12), 1098-1099.  
03-09-2018

Annexin A1 drives macrophage skewing towards a resolving phenotype to accelerate the regeneration of muscle injury through AMPK activation
MCARTHUR S, GOBBETTI T, Juban G, Desgeorges T, Theret M, Gondin J, Toller-Kawahisa J, Reutelingsperger C, PERRETTI M and Mounier R
Biorxiv vol. 375709 (375709), 1-1.  
29-08-2018

Ligand bias and its association with pro-resolving actions of melanocortin drugs
Patruno S, Garrido-Mesa J, Romano M, PERRETTI M and MONTERO MELENDEZ T
Frontiers in Pharmacology, Frontiers Media vol. 9 (919) 
14-08-2018

Characterization of a synovial B cell-derived 1 recombinant monoclonal antibody 2 targeting stromal calreticulin in the rheumatoid joints
PITZALIS C, CORSIERO E, JAGEMANN L, PERRETTI M and BOMBARDIERI M
Journal of Immunology, American Association of Immunologists 
25-07-2018

Author Correction: Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo
Qin CX, Finlayson SB, Al-Sharea A, Tate M, De Blasio MJ, Deo M, Rosli S, Prakoso D, Thomas CJ, Kiriazis H, Gould E, Yang YH, Morand EF, Perretti M, Murphy AJ, Du X-J, Gao X-M and Ritchie RH
Scientific Reports, Springer Nature vol. 8 (1) 
02-05-2018

Microvesicle Subsets in Sepsis Due to Community Acquired Pneumonia Compared to Faecal Peritonitis.
Lashin HMS, Nadkarni S, Oggero S, Jones HR, Knight JC, Hinds CJ and Perretti M
Shock vol. 49 (4), 393-401.  
01-04-2018

Formyl peptide receptor 1 signalling promotes experimental colitis in mice
Fusco R, Di Paola R, Gugliandolo E, D'Amico R, Perretti M and Cuzzocrea S
The Faseb Journal, Wiley vol. 32 (S1), 832.10-832.10.  
01-04-2018

Endogenous annexin A1 (AnxA1) modulates early‐phase gestation and offspring sex‐ratio skewing
Hebeda CB, Machado ID, Reif‐Silva I, Moreli JB, Oliani SM, Nadkarni S, Perretti M, Bevilacqua E and Farsky SHP
Journal of Cellular Physiology, Wiley vol. 233 (9), 6591-6603.  
07-03-2018

Neutrophil Microvesicles from Healthy Control and Rheumatoid Arthritis Patients Prevent the Inflammatory Activation of Macrophages
Rhys HI, Dell'Accio F, Pitzalis C, Moore A, Norling LV and Perretti M
Ebiomedicine, Elsevier vol. 29, 60-69.  
07-02-2018

Microvesicles in cardiovascular inflammation: markers or mediators of cardiovascular diseases?
Oggero S, Norling L and Perretti M
Proceedings For Annual Meeting of The Japanese Pharmacological Society, Japanese Pharmacological Society vol. WCP2018 
01-01-2018

Potential engagement of pathways of the resolution of inflammation as mechanism of action for plants on animal models
Piovezan AP and Perretti M
Journal of Ethnopharmacology, Elsevier vol. 221, 160-161.  
08-12-2017

Resolvins suppress tumor growth and enhance cancer therapy
Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR, Schmidt B, Dalli J, Greene ER, Gus-Brautbar Y, Piwowarski J, Mammoto T, Zurakowski D, Perretti M, Sukhatme VP, Kaipainen A, Kieran MW, Huang S and Panigrahy D
Journal of Experimental Medicine, Rockefeller University Press vol. 215 (1), 115-140.  
30-11-2017

Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo.
Qin CX, Finlayson SB, Ai-Sharea A, Tate M, De Blasio MJ, Deo M, Rosli S, Prakoso D, Thomas CJ, Kiriazis H, Gould E, Yang YH, Morand EF, Perretti M, Murphy AJ, Du X-J, Gao X-M and Ritchie RH
Sci Rep, Macmillan Publishers Limited, Part of Springer Nature vol. 7 (1), 16615-16615.  
30-11-2017

Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma.
Simeoli R, Montague K, Jones HR, Castaldi L, Chambers D, Kelleher JH, Vacca V, Pitcher T, Grist J, Al-Ahdal H, Wong L-F, Perretti M, Lai J, Mouritzen P, Heppenstall P and Malcangio M
Nat Commun, Macmillan Publishers Limited, Part of Springer Nature vol. 8 (1), 1778-1778.  
24-11-2017

Resolution in an 'over-inflamed' era
Perretti M and Montero-Melendez T
Biochemist vol. 39 (4), 4-7.  
01-08-2017

The resolution of acute inflammation induced by cyclic AMP is dependent on annexin A1
Lima KM, Vago JP, Caux TR, Negreiros-Lima GL, Sugimoto MA, Tavares LP, Arribada RG, Carmo AAF, Galvão I, Costa BRC, Soriani FM, Pinho V, Solito E, Perretti M, Teixeira MM and Sousa LP
Journal of Biological Chemistry, Elsevier vol. 292 (33), 13758-13773.  
27-06-2017

Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation
Gittens BR, Bodkin JV, Nourshargh S, Perretti M and Cooper D
The Journal of Immunology, Oxford University Press (Oup) vol. 198 (11), 4458-4469.  
01-06-2017

Actions of SPM in regulating host responses in arthritis
Perretti M and Norling LV
Molecular Aspects of Medicine, Elsevier vol. 58, 57-64.  
05-05-2017

Hydroalcoholic crude extract of Casearia sylvestris Sw. reduces chronic post-ischemic pain by activation of pro-resolving pathways
Piovezan AP, Batisti AP, Benevides MLACS, Turnes BL, Martins DF, Kanis L, Duarte ECW, Cavalheiro AJ, Bueno PCP, Seed MP, Norling LV, Cooper D, Headland S, Souza PRPS and Perretti M
Journal of Ethnopharmacology, Elsevier vol. 204, 179-188.  
13-04-2017

Characterizing the anti-inflammatory and tissue protective actions of a novel Annexin A1 peptide.
Perretti M, Di Filippo C, D'Amico M and Dalli J
Plos One, Public Library of Science vol. 12 (4), e0175786-e0175786.  
13-04-2017

The impact of environmental enrichment on the murine inflammatory immune response
Brod S, Gobbetti T, Gittens B, Ono M, Perretti M and D’Acquisto F
Jci Insight, American Society For Clinical Investigation vol. 2 (7) 
06-04-2017

Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection.
PERRETTI M, Dalli J, Colas R, Federici Canova D and Gobbetti T
Proceedings of The National Academy of Sciences of The United States of America, National Academy of Sciences vol. 114 (15), 3963-3968.  
29-03-2017

Aspirin‐triggered lipoxin A4 inhibits atherosclerosis progression in apolipoprotein E−/− mice
Petri MH, Laguna‐Fernandez A, Arnardottir H, Wheelock CE, Perretti M, Hansson GK and Bäck M
British Journal of Pharmacology, Wiley vol. 174 (22), 4043-4054.  
14-02-2017

Immune resolution mechanisms in inflammatory arthritis.
Perretti M, Cooper D, Dalli J and Norling LV
Nat Rev Rheumatol vol. 13 (2), 87-99.  
05-01-2017

Neutrophils induce proangiogenic T cells with a regulatory phenotype in pregnancy
NADKARNI SA, Smith J, Mauro C, Marelli-Berg FM, Perretti M, Sferruzzi-Perri AN, Ledwozyw A, Kishore M, Haas R, Williams DJ and Farsky S
, Editors: Medzhitov R. Proceedings of The National Academy of Sciences of Usa, National Academy of Sciences 
12-12-2016

Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3
Montero-Melendez T, Forfar RAE, Cook JM, Jerman JC, Taylor DL and Perretti M
Cellular and Molecular Life Sciences, Springer Nature vol. 74 (7), 1335-1345.  
16-11-2016

An orally administered butyrate‐releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium‐induced murine colitis
Simeoli R, Raso GM, Pirozzi C, Lama A, Santoro A, Russo R, Montero‐Melendez T, Canani RB, Calignano A, Perretti M and Meli R
British Journal of Pharmacology, Wiley vol. 174 (11), 1484-1496.  
03-11-2016

Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation.
Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M and Serhan CN
Journal of Immunology, American Association of Immunologists vol. 197 (6), 2362-2368.  
17-08-2016

Melanocortin agonism as a viable strategy to control alveolar bone loss induced by oral infection
Madeira MFM, Queiroz-Junior CM, Montero-Melendez T, Werneck SMC, Correa JD, Soriani FM, Garlet GP, Souza DG, Teixeira MM, Silva TA and Perretti M
The Faseb Journal, Federation of American Society of Experimental Biology (Faseb) 
17-08-2016

IkB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD
Chen J, Kieswich J, Chiazza F, Moyes A, Gobbetti T, Purvis G, Salvatori D, Patel N, Perretti M, Hobbs A, Collino M, Yaqoob M and THIEMERMANN C
Journal of The American Society of Nephrology, American Society of Nephrology 
06-05-2016

Fpr2/ALX Regulates Neutrophil-Platelet Aggregation and Attenuates Cerebral Inflammation: Impact for Therapy in Cardiovascular Disease
Vital SA, Becker F, Holloway PM, Russell J, Perretti M, Granger DN and Gavins FNE
Circulation, American Heart Association 
06-05-2016

Resolution of Inflammation: What Controls Its Onset?
Sugimoto MA, Sousa LP, Pinho V, Perretti M and Teixeira MM
Frontiers in Immunology, Frontiers Media vol. 7 
26-04-2016

Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN and Perretti M
Jci Insight, American Society For Clinical Investigation vol. 1 (5) 
21-04-2016

The role of neutrophils in inflammation resolution
Jones HR, Robb CT, Perretti M and Rossi AG
Seminars in Immunology vol. 28 (2), 137-145.  
01-04-2016

d‐Penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine‐γ‐lyase
Brancaleone V, Esposito I, Gargiulo A, Vellecco V, Asimakopoulou A, Citi V, Calderone V, Gobbetti T, Perretti M, Papapetropoulos A, Bucci M and Cirino G
British Journal of Pharmacology, Wiley vol. 173 (9), 1556-1565.  
23-03-2016

Annexin A1 Is a Physiological Modulator of Neutrophil Maturation and Recirculation Acting on the CXCR4/CXCL12 Pathway
Machado ID, Spatti M, Hastreiter A, Santin JR, Fock RA, Gil CD, Oliani SM, Perretti M and Farsky SHP
Journal of Cellular Physiology, Wiley vol. 231 (11), 2418-2427.  
08-03-2016

Proresolving Actions of Synthetic and Natural Protease Inhibitors Are Mediated by Annexin A1
Vago JP, Tavares LP, Sugimoto MA, Lima GLN, Galvão I, de Caux TR, Lima KM, Ribeiro ALC, Carneiro FS, Nunes FFC, Pinho V, Perretti M, Teixeira MM and Sousa LP
The Journal of Immunology, Oxford University Press (Oup) vol. 196 (4), 1922-1932.  
15-02-2016

The role of the Annexin-A1/FPR2 system in the regulation of mast cell degranulation provoked by compound 48/80 and in the inhibitory action of nedocromil
Sinniah A, Yazid S, Perretti M, Solito E and Flower RJ
International Immunopharmacology, Elsevier vol. 32, 87-95.  
21-01-2016

Activation of Melanocortin Receptors MC1 and MC5 Attenuates Retinal Damage in Experimental Diabetic Retinopathy
Rossi S, Maisto R, Gesualdo C, Trotta MC, Ferraraccio F, Kaneva MK, Getting SJ, Surace E, Testa F, Simonelli F, Grieco P, Merlino F, Perretti M, D’Amico M and Di Filippo C
Mediators of Inflammation, Hindawi vol. 2016 (1) 
01-01-2016

Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis
Headland SE, Jones HR, Norling LV, Kim A, Souza PR, Corsiero E, Gil CD, Nerviani A, Dell'Accio F, Pitzalis C, Oliani SM, Jan LY and Perretti M
Science Translational Medicine, American Association For The Advancement of Science (Aaas) vol. 7 (315) 
25-11-2015

Resolution Pharmacology: Opportunities for Therapeutic Innovation in Inflammation
Perretti M, Leroy X, Bland EJ and Montero-Melendez T
Trends in Pharmacological Sciences, Elsevier vol. 36 (11), 737-755.  
01-11-2015

Alpha-2-macroglobulin loaded microcapsules enhance human leukocyte functions and innate immune response
Canova DF, Pavlov AM, Norling LV, Gobbetti T, Brunelleschi S, Le Fauder P, Cenac N, Sukhorukov GB and Perretti M
Journal of Controlled Release, Elsevier vol. 217, 284-292.  
16-09-2015

Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo
Eldridge S, Nalesso G, Ismail H, Vicente-Greco K, Kabouridis P, Ramachandran M, Niemeier A, Herz J, Pitzalis C, Perretti M and Dell'Accio F
Annals of The Rheumatic Diseases, Elsevier vol. 75 (6), 1228-1235.  
19-08-2015

Definition of a Novel Pathway Centered on Lysophosphatidic Acid To Recruit Monocytes during the Resolution Phase of Tissue Inflammation
McArthur S, Gobbetti T, Kusters DHM, Reutelingsperger CP, Flower RJ and Perretti M
The Journal of Immunology, Oxford University Press (Oup) vol. 195 (3), 1139-1151.  
01-08-2015

Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions
Haas R, Smith J, Rocher-Ros V, Nadkarni S, Montero-Melendez T, D’Acquisto F, Bland EJ, Bombardieri M, Pitzalis C, Perretti M, Marelli-Berg FM and Mauro C
Plos Biology, Public Library of Science (Plos) vol. 13 (7) 
16-07-2015

Both MC1 and MC3 Receptors Provide Protection From Cerebral Ischemia-Reperfusion–Induced Neutrophil Recruitment
Holloway PM, Durrenberger PF, Trutschl M, Cvek U, Cooper D, Orr AW, Perretti M, Getting SJ and Gavins FNE
Arteriosclerosis Thrombosis and Vascular Biology, Wolters Kluwer vol. 35 (9), 1936-1944.  
25-06-2015

Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet
Kusters DHM, Chatrou ML, Willems BAG, De Saint-Hubert M, Bauwens M, van der Vorst E, Bena S, Biessen EAL, Perretti M, Schurgers LJ and Reutelingsperger CPM
Plos One, Public Library of Science (Plos) vol. 10 (6) 
19-06-2015

The resolution of inflammation: New mechanisms in patho-physiology open opportunities for pharmacology
Perretti M
Seminars in Immunology, Elsevier vol. 27 (3), 145-148.  
01-05-2015

Annexin A1 mimetic peptide controls the inflammatory and fibrotic effects of silica particles in mice
Trentin PG, Ferreira TPT, Arantes ACS, Ciambarella BT, Cordeiro RSB, Flower RJ, Perretti M, Martins MA and Silva PMR
British Journal of Pharmacology, Wiley vol. 172 (12), 3058-3071.  
10-04-2015

R J Flower and M Perretti
Flower RJ and Perretti M
British Journal of Pharmacology, Wiley vol. 172 (7), 1651-1652.  
16-03-2015

Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects.
Montero-Melendez T, Gobbetti T, Cooray SN, Jonassen TE and Perretti M
J Immunol, The American Association of Immunologists, Inc. vol. 194 (7), 3381-3388.  
27-02-2015

Characterization of the anti-inflammatory properties of NCX 429, a dual-acting compound releasing nitric oxide and naproxen
Amoruso A, Fresu LG, Dalli J, Miglietta D, Bardelli C, Canova DF, Perretti M and Brunelleschi S
Life Sciences, Elsevier vol. 126, 28-36.  
21-02-2015

Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice
Fredman G, Kamaly N, Spolitu S, Milton J, Ghorpade D, Chiasson R, Kuriakose G, Perretti M, Farokzhad O and Tabas I
Science Translational Medicine, American Association For The Advancement of Science (Aaas) vol. 7 (275) 
18-02-2015

Annexin A1–containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair
Leoni G, Neumann P-A, Kamaly N, Quiros M, Nishio H, Jones HR, Sumagin R, Hilgarth RS, Alam A, Fredman G, Argyris I, Rijcken E, Kusters D, Reutelingsperger C, Perretti M, Parkos CA, Farokhzad OC, Neish AS and Nusrat A
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 125 (3), 1215-1227.  
09-02-2015

Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor.
Gobbetti T, Ducheix S, le Faouder P, Perez T, Riols F, Boue J, Bertrand-Michel J, Dubourdeau M, Guillou H, Perretti M, Vergnolle N and Cenac N
Br J Pharmacol vol. 172 (3), 910-923.  
01-02-2015

Identification of a novel recycling sequence in the C-tail of FPR2/ALX receptor: association with cell protection from apoptosis.
Thompson D, McArthur S, Hislop JN, Flower RJ and Perretti M
J Biol Chem vol. 289 (52), 36166-36178.  
26-12-2014

Formyl Peptide Receptor as a Novel Therapeutic Target for Anxiety-Related Disorders
Gallo I, Rattazzi L, Piras G, Gobbetti T, Panza E, Perretti M, Dalley JW and D'Acquisto F
Plos One, Public Library of Science (Plos) vol. 9 (12) 
17-12-2014

Aspirin-triggered 15-epi-lipoxin A4 signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation
Petri MH, Laguna-Fernandez A, Tseng C-N, Hedin U, Perretti M and Bäck M
International Journal of Cardiology, Elsevier vol. 179, 370-372.  
05-11-2014

Alterations in the profile of blood neutrophil membrane receptors caused by in vivo adrenocorticotrophic hormone actions.
Machado ID, Santin JR, Drewes CC, Gil CD, Oliani SM, Perretti M and Farsky SHP
Am J Physiol Endocrinol Metab vol. 307 (9), E754-E763.  
01-11-2014

Annexin A1 mediates hydrogen sulfide properties in the control of inflammation.
Brancaleone V, Mitidieri E, Flower RJ, Cirino G and Perretti M
J Pharmacol Exp Ther vol. 351 (1), 96-104.  
01-10-2014

Gapdh gene expression is modulated by inflammatory arthritis and is not suitable for qPCR normalization.
Montero-Melendez T and Perretti M
Inflammation vol. 37 (4), 1059-1069.  
01-08-2014

Resolution of inflammation: targeting GPCRs that interact with lipids and peptides.
Cash JL, Norling LV and Perretti M
Drug Discov Today vol. 19 (8), 1186-1192.  
01-08-2014

Resolution of inflammation: examples of peptidergic players and pathways.
Ahmed TJ, Kaneva MK, Pitzalis C, Cooper D and Perretti M
Drug Discov Today vol. 19 (8), 1166-1171.  
01-08-2014

Association between periodontal disease and inflammatory arthritis reveals modulatory functions by melanocortin receptor type 3.
Montero-Melendez T, Madeira MFM, Norling LV, Alsam A, Curtis MA, da Silva TA and Perretti M
Am J Pathol vol. 184 (8), 2333-2341.  
01-08-2014

Connections in pharmacology: innovation serving translational medicine.
Montero-Melendez T and Perretti M
Drug Discov Today vol. 19 (7), 820-823.  
01-07-2014

Cutting-edge analysis of extracellular microparticles using ImageStream(X) imaging flow cytometry.
Headland SE, Jones HR, D'Sa ASV, Perretti M and Norling LV
Sci Rep vol. 4 
10-06-2014

Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation.
Fu H, Kishore M, Gittens B, Wang G, Coe D, Komarowska I, Infante E, Ridley AJ, Cooper D, Perretti M and Marelli-Berg FM
Nat Commun vol. 5 
14-03-2014

Investigational analysis reveals a potential role for neutrophils in giant-cell arteritis disease progression.
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B and Perretti M
Circ Res vol. 114 (2), 242-248.  
17-01-2014

Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis.
Dalli J, Norling LV, Montero-Melendez T, Federici Canova D, Lashin H, Pavlov AM, Sukhorukov GB, Hinds CJ and Perretti M
Embo Mol Med vol. 6 (1), 27-42.  
01-01-2014

Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain
Old EA, Nadkarni S, Grist J, Gentry C, Bevan S, Kim K-W, Mogg AJ, Perretti M and Malcangio M
Journal of Clinical Investigation vol. 124 (5), 2023-2036.  
01-01-2014

Endogenous Annexin A1 Is a Novel Protective Determinant in Nonalcoholic Steatohepatitis in Mice
Locatelli I, Sutti S, Jindal A, Vacchiano M, Bozzola C, Reutelingsperger C, Kusters D, Bena S, Parola M, Paternostro C, Bugianesi E, McArthur S, Albano E and Perretti M
Hepatology vol. 60 (2), 531-544.  
01-01-2014

AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE^-/- mice
Burgmaier M, Schutters K, Willems B, Van der Vorst EPC, Kusters D, Chatrou M, Norling L, Biessen EAL, Cleutjens J, Perretti M, Schurgers LJ and Reutelingsperger CPM
Journal of Cellular and Molecular Medicine vol. 18 (10), 2117-2124.  
01-01-2014

Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses.
Cooray SN, Gobbetti T, Montero-Melendez T, McArthur S, Thompson D, Clark AJL, Flower RJ and Perretti M
Proc Natl Acad Sci U S A vol. 110 (45), 18232-18237.  
05-11-2013

Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23.
Cash JL, Bena S, Headland SE, McArthur S, Brancaleone V and Perretti M
Embo Rep vol. 14 (11), 999-1007.  
01-11-2013

Annexin-A1 Peptide Ac2-26
Perretti M, D'Acquisto F and Flower RJ
In Handbook of Biologically Active Peptides 631-639.  
29-08-2013

Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.
Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M and Perretti M
Mol Cell Proteomics vol. 12 (8), 2205-2219.  
01-08-2013

A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation.
Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S and Perretti M
Blood vol. 122 (4), 608-617.  
25-07-2013

Endogenous galectin-1 exerts tonic inhibition on experimental arthritis.
Iqbal AJ, Cooper D, Vugler A, Gittens BR, Moore A and Perretti M
J Immunol vol. 191 (1), 171-177.  
01-07-2013

Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A4 receptor.
Dalli J, Consalvo AP, Ray V, Di Filippo C, D'Amico M, Mehta N and Perretti M
J Immunol vol. 190 (12), 6478-6487.  
15-06-2013

The role of omega-3 derived resolvins in arthritis.
Norling LV and Perretti M
Curr Opin Pharmacol vol. 13 (3), 476-481.  
01-06-2013

SP0144 The Role of Omega-3 Derived Resolvins in Arthritis
Perretti M
Annals of The Rheumatic Diseases, Elsevier vol. 72 
01-06-2013

Tu1993 Protective Effects of N-6 Polyunsaturated Fatty Acid Diet on Intestinal Ischemia/Reperfusion Injury Are Centererd on Lipoxin A4 and Its Receptor
Gobbetti T, Ducheix S, Le Faouder P, Boue J, Bertrand-Michel J, Guillou H, Perretti M, Vergnolle N and Cenac N
Gastroenterology, Elsevier vol. 144 (5), s-899.  
01-05-2013

An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis.
Ryan SM, McMorrow J, Umerska A, Patel HB, Kornerup KN, Tajber L, Murphy EP, Perretti M, Corrigan OI and Brayden DJ
J Control Release vol. 167 (2), 120-129.  
28-04-2013

Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors.
Montero-Melendez T, Dalli J and Perretti M
Cell Death Differ vol. 20 (4), 567-575.  
01-04-2013

Agrin expression is downregulated in OA and is required for chondrocyte differentiation
Eldridge S, Vicent-Greco K, Nalesso G, Pitzalis C, Perretti M, Kabouridis P and Dell'Accio F
Osteoarthritis and Cartilage, Elsevier vol. 21, s112-s113.  
01-04-2013

Adipose tissue-specific modulation of galectin expression in lean and obese mice: evidence for regulatory function.
Rhodes DH, Pini M, Castellanos KJ, Montero-Melendez T, Cooper D, Perretti M and Fantuzzi G
Obesity (Silver Spring) vol. 21 (2), 310-319.  
01-02-2013

Cell surface-expressed phosphatidylserine as therapeutic target to enhance phagocytosis of apoptotic cells.
Schutters K, Kusters DHM, Chatrou MLL, Montero-Melendez T, Donners M, Deckers NM, Krysko DV, Vandenabeele P, Perretti M, Schurgers LJ and Reutelingsperger CPM
Cell Death Differ vol. 20 (1), 49-56.  
01-01-2013

Control of myeloid cell trafficking in resolution.
Norling LV and Perretti M
J Innate Immun vol. 5 (4), 367-376.  
01-01-2013

Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin Peptides.
Ahmed TJ, Montero-Melendez T, Perretti M and Pitzalis C
Int J Inflam vol. 2013 
01-01-2013

Novel pathways in the yin-yang of immunomodulation
Godson C and Perretti M
Current Opinion in Pharmacology vol. 13 (4), 543-546.  
01-01-2013

Attenuation of plasma annexin A1 in human obesity
Kosicka A, Cunliffe AD, Mackenzie R, Zariwala MG, Perretti M, Flower RJ and Renshaw D
Faseb Journal vol. 27 (1), 368-378.  
01-01-2013

The calcitonin and glucocorticoids combination: mechanistic insights into their class-effect synergy in experimental arthritis.
Al-Kashi A, Montero-Melendez T, Moradi-Bidhendi N, Gilligan JP, Mehta N and Perretti M
Plos One vol. 8 (2) 
01-01-2013

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair
Leoni G, Alam A, Neumann P-A, Lambeth JD, Cheng G, McCoy J, Hilgarth RS, Kundu K, Murthy N, Kusters D, Reutelingsperger C, Perretti M, Parkos CA, Neish AS and Nusrat A
Journal of Clinical Investigation vol. 123 (1), 443-454.  
01-01-2013

Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO mice.
Pang J, Rhodes DH, Pini M, Akasheh RT, Castellanos KJ, Cabay RJ, Cooper D, Perretti M and Fantuzzi G
Plos One vol. 8 (2) 
01-01-2013

Smooth muscle cells in human atherosclerosis: Proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease
Viiri LE, Full LE, Navin TJ, Begum S, Didangelos A, Astola N, Berge RK, Seppala I, Shalhoub J, Franklin IJ, Perretti M, Lehtimaki T, Davies AH, Wait R and Monaco C
Journal of Molecular and Cellular Cardiology vol. 54, 65-72.  
01-01-2013

Resolution of inflammation: an integrated view
Ortega-Gomez A, Perretti M and Soehnlein O
Embo Molecular Medicine vol. 5 (5), 661-674.  
01-01-2013

Annexin-A1 protein and its relationship to cortisol in human saliva
Fowkes RC, Moradi-Bidhendi N, Branceleone V, Zariwala MG, Brady D, Jessop DS, Perretti M and Renshaw D
Psychoneuroendocrinology vol. 38 (5), 722-727.  
01-01-2013

Biphasic modulation of NOS expression, protein and nitrite products by hydroxocobalamin underlies its protective effect in endotoxemic shock: downstream regulation of COX-2, IL-1β, TNF-α, IL-6, and HMGB1 expression.
Sampaio ALF, Dalli J, Brancaleone V, D'Acquisto F, Perretti M and Wheatley C
Mediators Inflamm vol. 2013 
01-01-2013

Identification of novel predictor classifiers for inflammatory bowel disease by gene expression profiling.
Montero-Meléndez T, Llor X, García-Planella E, Perretti M and Suárez A
Plos One vol. 8 (10) 
01-01-2013

Chapter 86 Annexin-A1 Peptide Ac2–26
Perretti M, D’Acquisto F and Flower RJ
In Handbook of Biologically Active Peptides, Elsevier 631-639.  
01-01-2013

The impact of endogenous annexin A1 on glucocorticoid control of inflammatory arthritis.
Patel HB, Kornerup KN, Sampaio ALF, D'Acquisto F, Seed MP, Girol AP, Gray M, Pitzalis C, Oliani SM and Perretti M
Ann Rheum Dis vol. 71 (11), 1872-1880.  
01-11-2012

Editorial: to resolve or not to resolve: annexin A1 pushes resolution on track.
Perretti M
J Leukoc Biol vol. 92 (2), 245-247.  
01-08-2012

Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions.
Norling LV, Dalli J, Flower RJ, Serhan CN and Perretti M
Arterioscler Thromb Vasc Biol vol. 32 (8), 1970-1978.  
01-08-2012

Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signaling.
Bena S, Brancaleone V, Wang JM, Perretti M and Flower RJ
J Biol Chem vol. 287 (29), 24690-24697.  
13-07-2012

Distinct localization of T cell Agrin during antigen presentation--evidence for the expression of Agrin receptor(s) in antigen-presenting cells.
Kabouridis PS, Pimentel TA, Brancaleone V, D'Acquisto F, Oliani SM, Perretti M and Jury EC
Febs J vol. 279 (13), 2368-2380.  
01-07-2012

The peritoneal tumour microenvironment of high-grade serous ovarian cancer.
Leinster DA, Kulbe H, Everitt G, Thompson R, Perretti M, Gavins FNE, Cooper D, Gould D, Ennis DP, Lockley M, McNeish IA, Nourshargh S and Balkwill FR
J Pathol vol. 227 (2), 136-145.  
01-06-2012

Prednisolone exerts exquisite inhibitory properties on platelet functions.
Liverani E, Banerjee S, Roberts W, Naseem KM and Perretti M
Biochem Pharmacol vol. 83 (10), 1364-1373.  
15-05-2012

The impact of endogenous annexin A1 on glucocorticoid control of inflammatory arthritis
Patel HB, Kornerup KN, Sampaio ALFS, D'Acquisto F, Seed MP, Girol AP, Gray M, Pitzalis C, Oliani SM and Perretti M
Annals of The Rheumatic Diseases 
05-05-2012

The effect of galectins on leukocyte trafficking in inflammation: sweet or sour?
Cooper D, Iqbal AJ, Gittens BR, Cervone C and Perretti M
Ann N Y Acad Sci vol. 1253, 181-192.  
01-04-2012

Mapping pathogenesis of arthritis through small animal models
Vincent TL, Williams RO, Maciewicz R, Silman A, Garside P and group FTARUAMW
Rheumatology, Oxford University Press (Oup) vol. 51 (11), 1931-1941.  
16-03-2012

Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves.
Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Del Carro U, Zambroni D, Brain SD, Perretti M, Ahluwalia A, Priestley JV, Chavakis T, Imhof BA, Feltri ML and Nourshargh S
Faseb J vol. 26 (3), 1064-1076.  
01-03-2012

Actions of translocator protein ligands on neutrophil adhesion and motility induced by G-protein coupled receptor signaling.
de Lima CB, Tamura EK, Montero-Melendez T, Palermo-Neto J, Perretti M, Markus RP and Farsky SHP
Biochem Biophys Res Commun vol. 417 (2), 918-923.  
13-01-2012

Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow.
Dalli J, Jones CP, Cavalcanti DM, Farsky SH, Perretti M and Rankin SM
Faseb J vol. 26 (1), 387-396.  
01-01-2012

Molecular engineering of short half-life small peptides (VIP, αMSH and γ₃MSH) fused to latency-associated peptide results in improved anti-inflammatory therapeutics.
Vessillier S, Adams G, Montero-Melendez T, Jones R, Seed M, Perretti M and Chernajovsky Y
Ann Rheum Dis vol. 71 (1), 143-149.  
01-01-2012

Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils.
Dalli J, Montero-Melendez T, McArthur S and Perretti M
Front Pharmacol vol. 3 
01-01-2012

Acute myocardial infarction in streptozotocin-induced hyperglycaemic rats: protection by a carbon monoxide-releasing molecule (CORM-3)
Di Filippo C, Perretti M, Rossi F, Ferraraccio F, Motterlini R and D'Amico M
Naunyn-Schmiedebergs Archives of Pharmacology vol. 385 (2), 137-144.  
01-01-2012

Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model
Clark AK, Grist J, Al-Kashi A, Perretti M and Malcangio M
Arthritis and Rheumatism vol. 64 (6), 2038-2047.  
01-01-2012

Up-Regulation of Annexin-A1 and Lipoxin A₄ in Individuals with Ulcerative Colitis May Promote Mucosal Homeostasis
Vong L, Ferraz JGP, Dufton N, Panaccione R, Beck PL, Sherman PM, Perretti M and Wallace JL
Plos One vol. 7 (6) 
01-01-2012

Genetic Ablation of the Fpr1 Gene Confers Protection from Smoking-Induced Lung Emphysema in Mice
Cardini S, Dalli J, Fineschi S, Perretti M, Lungarella G and Lucattelli M
American Journal of Respiratory Cell and Molecular Biology vol. 47 (3), 332-339.  
01-01-2012

High density micromass cultures of a human chondrocyte cell line: a reliable assay system to reveal the modulatory functions of pharmacological agents.
Greco KV, Iqbal AJ, Rattazzi L, Nalesso G, Moradi-Bidhendi N, Moore AR, Goldring MB, Dell'Accio F and Perretti M
Biochem Pharmacol vol. 82 (12), 1919-1929.  
15-12-2011

Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes.
Nadkarni S, Cooper D, Brancaleone V, Bena S and Perretti M
Arterioscler Thromb Vasc Biol vol. 31 (11), 2749-2759.  
01-11-2011

Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis.
Damazo AS, Sampaio AL, Nakata CM, Flower RJ, Perretti M and Oliani SM
Bmc Immunol vol. 12 
19-10-2011

Melanocortin receptors as novel effectors of macrophage responses in inflammation
Patel HB, Montero-Melendez T, Greco KV and Perretti M
, Editors: Ariel A. Frontiers in Immunology vol. 2, 1-6.  
13-09-2011

The melanocortin agonist AP214 exerts anti-inflammatory and proresolving properties.
Montero-Melendez T, Patel HB, Seed M, Nielsen S, Jonassen TEN and Perretti M
Am J Pathol vol. 179 (1), 259-269.  
01-07-2011

Sphingosine-1-phosphate modulates vascular permeability and cell recruitment in acute inflammation in vivo.
Roviezzo F, Brancaleone V, De Gruttola L, Vellecco V, Bucci M, D'Agostino B, Cooper D, Sorrentino R, Perretti M and Cirino G
J Pharmacol Exp Ther vol. 337 (3), 830-837.  
01-06-2011

IL-17A increases ADP-induced platelet aggregation.
Maione F, Cicala C, Liverani E, Mascolo N, Perretti M and D'Acquisto F
Biochem Biophys Res Commun vol. 408 (4), 658-662.  
20-05-2011

Cutting Edge: Humanized Nano-Proresolving Medicines Mimic Inflammation-Resolution and Enhance Wound Healing
Norling LV, Spite M, Yang R, Flower RJ, Perretti M and Serhan CN
J Immunol vol. 186 (10), 5543-5547.  
15-05-2011

Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin.
Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ and Ahluwalia A
Arterioscler Thromb Vasc Biol vol. 31 (5), 1075-1083.  
01-05-2011

Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature.
Brancaleone V, Dalli J, Bena S, Flower RJ, Cirino G and Perretti M
J Immunol vol. 186 (8), 4905-4914.  
15-04-2011

Role of melanocortin receptors in the regulation of gouty inflammation.
Montero-Melendez T, Patel HB and Perretti M
Curr Rheumatol Rep vol. 13 (2), 138-145.  
01-04-2011

Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect.
Iqbal AJ, Sampaio ALF, Maione F, Greco KV, Niki T, Hirashima M, Perretti M and Cooper D
Am J Pathol vol. 178 (3), 1201-1209.  
01-03-2011

Microvascular thrombosis and CD40/CD40L signaling.
Gavins FNE, Li G, Russell J, Perretti M and Granger DN
J Thromb Haemost vol. 9 (3), 574-581.  
01-03-2011

Corrections: Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC, Perretti M and Flower RJ
The Journal of Immunology, Oxford University Press (Oup) vol. 186 (4), 2684-2685.  
15-02-2011

Cross-talk between minimally primed HL-60 cells and resting HUVEC reveals a crucial role for adhesion over extracellularly released oxidants
Allegra M, D'Acquisto F, Tesoriere L, Livrea MA and Perretti M
Biochem Pharmacol vol. 81 (3), 396-401.  
01-02-2011

Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids
Colucci M, Mastriota M, Maione F, Di Giannuario A, Mascolo N, Palmery M, Severini C, Perretti M and Pieretti S
Peptides vol. 32 (2), 266-271.  
01-02-2011

Melanocortin receptors as novel effectors of macrophage responses in inflammation.
Patel HB, Montero-Melendez T, Greco KV and Perretti M
Front Immunol vol. 2 
01-01-2011

An essential role for mast cells as modulators of neutrophils influx in collagen-induced arthritis in the mouse.
Pimentel TA, Sampaio ALF, D'Acquisto F, Perretti M and Oliani SM
Lab Invest vol. 91 (1), 33-42.  
01-01-2011

Analysis of the inflammatory response in HY-TCR transgenic mice highlights the pathogenic potential of CD4- CD8- T cells.
Maione F, Paschalidis N, Iqbal AJ, Crompton T, Perretti M and D'Acquisto F
Autoimmunity vol. 43 (8), 672-681.  
01-12-2010

Human RCAN3 gene expression and cell growth in endothelial cells
Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D and Perretti M
Int J Mol Med vol. 26 (6), 913-918.  
01-12-2010

Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis.
Patel HB, Bombardieri M, Sampaio ALF, D'Acquisto F, Gray M, Grieco P, Getting SJ, Pitzalis C and Perretti M
Faseb J vol. 24 (12), 4835-4843.  
01-12-2010

Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature.
Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M and D'Acquisto F
Blood vol. 116 (20), 4288-4296.  
18-11-2010

FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis.
Maderna P, Cottell DC, Toivonen T, Dufton N, Dalli J, Perretti M and Godson C
Faseb J vol. 24 (11), 4240-4249.  
01-11-2010

Human RCAN3 gene expression and cell growth in endothelial cells.
Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D and Perretti M
International Journal of Molecular Medicine, Spandidos Publications vol. 26 (6), 913-918.  
21-10-2010

Downstream gene activation of the receptor ALX by the agonist annexin A1.
Renshaw D, Montero-Melendez T, Dalli J, Kamal A, Brancaleone V, D'Acquisto F, Cirino G and Perretti M
Plos One vol. 5 (9) 
17-09-2010

Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization.
Yazid S, Leoni G, Getting SJ, Cooper D, Solito E, Perretti M and Flower RJ
Arterioscler Thromb Vasc Biol vol. 30 (9), 1718-1724.  
01-09-2010

Anti‐inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis
Patel HB, Bombardieri M, Sampaio ALF, D’Acquisto F, Gray M, Grieco P, Getting SJ, Pitzalis C and Perretti M
The Faseb Journal, Wiley vol. 24 (12), 4835-4843.  
11-08-2010

Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists.
Dufton N and Perretti M
Pharmacol Ther vol. 127 (2), 175-188.  
01-08-2010

CFTR Inhibition Provokes an Inflammatory Response Associated with an Imbalance of the Annexin A1 Pathway
Dalli J, Rosignoli G, Hayhoe RPG, Edelman A and Perretti M
Am J Pathol vol. 177 (1), 176-186.  
01-07-2010

Inflammation-dependent alpha 5 beta 1 (very late antigen-5) expression on leukocytes reveals a functional role for this integrin in acute peritonitis.
Sampaio ALF, Zahn G, Leoni G, Vossmeyer D, Christner C, Marshall JF and Perretti M
J Leukoc Biol vol. 87 (5), 877-884.  
01-05-2010

The melanocortin MC(1) receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculature.
Leoni G, Voisin M-B, Carlson K, Getting S, Nourshargh S and Perretti M
Br J Pharmacol vol. 160 (1), 171-180.  
01-05-2010

Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo
Semple F, Webb S, Li HN, Patel HB, Perretti M, Jackson IJ, Gray M, Davidson DJ and Dorin JR
Eur J Immunol vol. 40 (4), 1073-1078.  
01-04-2010

Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation.
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC, Perretti M and Flower RJ
J Immunol vol. 184 (5), 2611-2619.  
01-03-2010

Enhanced neutrophil expression of annexin-1 in coronary artery disease
Sarndahl E, Bergstrom I, Nijm J, Forslund T, Perretti M and Jonasson L
Metabolism vol. 59 (3), 433-440.  
01-03-2010

Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection
Paschalidis N, Huggins A, Rowbotham NJ, Furmanski AL, Crompton T, Flower RJ, Perretti M and D'Acquisto F
Cell Cycle vol. 9 (4), 785-794.  
15-02-2010

Melanocortin Control of Cell Trafficking in Vascular Inflammation
Patel HB, Leoni G, Melendez TM, Sampaio ALF and Perretti M
88-106.  
01-01-2010

Selective Inhibitors of Kv11.1 Regulate IL-6 Expression by Macrophages in Response to TLR/IL-1R Ligands
Hunter C, Kadakia TB, Cooper D, Perretti M, Schwartz RC and Brown SB
Thescientificworldjournal vol. 10, 1580-1596.  
01-01-2010

Human RCAN3 gene expression and cell growth in endothelial cells
Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D and Perretti M
International Journal of Molecular Medicine vol. 26 (6), 913-918.  
01-01-2010

The Cardio-Protective Properties of Ncx-6550, a Nitric Oxide Donating Pravastatin, in the Mouse
Di Filippo C, Monopoli A, Ongini E, Perretti M and D'Amico M
Microcirculation vol. 17 (6), 417-426.  
01-01-2010

Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate.
Cooper D, Ilarregui JM, Pesoa SA, Croci DO, Perretti M and Rabinovich GA
199-244.  
01-01-2010

Comparative analysis of Annexin A1-Formyl Peptide Receptor 2/ALX expression in human leukocyte subsets
Spurr L, Nadkarni S, Pederzoli-Ribeil M, Goulding NJ, Perretti M and D'Acquisto F
International Immunopharmacology, Elsevier vol. 11 (1), 55-66.  
01-01-2010

Modulation of experimental autoimmune encephalomyelitis by endogenous annexin A1.
Paschalidis N, Iqbal AJ, Maione F, Wood EG, Perretti M, Flower RJ and D'Acquisto F
J Neuroinflammation vol. 6 
13-11-2009

Laminar shear stress regulates endothelial kinin B1 receptor expression and function: potential implication in atherogenesis.
Duchene J, Cayla C, Vessillier S, Scotland R, Yamashiro K, Lecomte F, Syed I, Vo P, Marrelli A, Pitzalis C, Cipollone F, Schanstra J, Bascands J-L, Hobbs AJ, Perretti M and Ahluwalia A
Arterioscler Thromb Vasc Biol vol. 29 (11), 1757-1763.  
01-11-2009

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis
Spite M, Norling LV, Summers L, Yang R, Cooper D, Petasis NA, Flower RJ, Perretti M and Serhan CN
Nature vol. 461 (7268), 1287-U125.  
29-10-2009

Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics.
Perretti M and Dalli J
Br J Pharmacol vol. 158 (4), 936-946.  
01-10-2009

297 INVESTIGATION OF THE ROLE OF FORMYL PEPTIDE RECEPTOR IN ACUTE NOCICEPTION USING GENE‐DEFICIENT MICE
Pieretti S, di Giannuario A, Colucci M, Mastriota M and Perretti M
European Journal of Pain, Wiley vol. 13 (S1), s92a-ss92.  
01-09-2009

Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages
McColl A, Bournazos S, Franz S, Perretti M, Morgan BP, Haslett C and Dransfield I
J Immunol vol. 183 (3), 2167-2175.  
01-08-2009

Quantitative Analysis of Promoter Activity by Green Fluorescent Protein (GFP) Target/Reporter Strategy in a Novel Transgenic alx/fpr-rs2 Null Mouse
Dufton NP, Hannon R, Perretti M and Flower R
Inflammation Research, Springer Nature vol. 58 (Suppl 2), s252-s255.  
01-07-2009

Activation of PPAR beta/delta inhibits leukocyte recruitment, cell adhesion molecule expression, and chemokine release
Piqueras L, Sanz MJ, Perretti M, Morcillo E, Norling L, Mitchell JA, Li Y and Bishop-Bailey D
J Leukocyte Biol vol. 86 (1), 115-122.  
01-07-2009

Endogenous galectins and the control of the host inflammatory response.
Norling LV, Perretti M and Cooper D
J Endocrinol vol. 201 (2), 169-184.  
01-05-2009

Activation of melanocortin receptor type 3 as a new strategy to control experimental and rheumatoid arthritis
Patel HB, Bombardieri M, Pitzalis C and Perretti M
Eur J Clin Invest vol. 39, 29-29.  
01-04-2009

The impact of Annexin-A1 cleavage on neutrophil behaviour during vascular inflammation
Pederzoli-Ribeil M, Maione F, Perretti M and D'Acquisto F
Eur J Clin Invest vol. 39, 37-37.  
01-04-2009

Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation.
Huggins A, Paschalidis N, Flower RJ, Perretti M and D'Acquisto F
Faseb J vol. 23 (4), 985-996.  
01-04-2009

Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study.
Tripatara P, Patel NSA, Brancaleone V, Renshaw D, Rocha J, Sepodes B, Mota-Filipe H, Perretti M and Thiemermann C
Eur J Pharmacol vol. 606 (1-3), 205-209.  
15-03-2009

Interleukin 17 sustains rather than induces inflammation.
Maione F, Paschalidis N, Mascolo N, Dufton N, Perretti M and D'Acquisto F
Biochem Pharmacol vol. 77 (5), 878-887.  
01-03-2009

A Novel Peptide Agonist of Formyl-Peptide Receptor-Like 1 (ALX) Displays Anti-Inflammatory and Cardioprotective Effects
Hecht I, Rong J, Sampaio ALF, Hermesh C, Rutledge C, Shemesh R, Toporik A, Beiman M, Dassa L, Niv H, Cojocaru G, Zauberman A, Rotman G, Perretti M, Vinten-Johansen J and Cohen Y
J Pharmacol Exp Ther vol. 328 (2), 426-434.  
01-02-2009

Functional and Ultrastructural Analysis of Annexin A1 and Its Receptor in Extravasating Neutrophils during Acute Inflammation
Gastardelo TS, Damazo AS, Dalli J, Flower RJ, Perretti M and Oliani SM
Am J Pathol vol. 174 (1), 177-183.  
01-01-2009

Annexin A1 and glucocorticoids as effectors of the resolution of inflammation.
Perretti M and D'Acquisto F
Nat Rev Immunol vol. 9 (1), 62-70.  
01-01-2009

Annexin A1 reguliert intestinale Mukosaschäden, Entzündung und Regeneration
Laukoetter MG, Babbin BA, Nava P, Koch S, Lee WY, Capaldo CT, Peatman E, Severson EA, Flower RJ, Perretti M, Parkos CA and Nusrat A
In Chirurgisches Forum Und Dgav Forum 2009, Springer Nature 225-227.  
01-01-2009

A role for MC3R in modulating lung inflammation
Getting SJ, Riffo-Vasquez Y, Pitchford S, Kaneva M, Grieco P, Page CP, Perretti M and Spina D
Pulm Pharmacol Ther vol. 21 (6), 866-873.  
01-12-2008

Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.
Leoni G, Patel HB, Sampaio ALF, Gavins FNE, Murray JF, Grieco P, Getting SJ and Perretti M
Faseb J vol. 22 (12), 4228-4238.  
01-12-2008

Annexin A1 regulates intestinal mucosal injury, inflammation, and repair
Babbin BA, Laukoetter MG, Nava P, Koch S, Lee WY, Capaldo CT, Peatman E, Severson EA, Flower RJ, Perretti M, Parkos CA and Nusrat A
J Immunol vol. 181 (7), 5035-5044.  
01-10-2008

Fluctuation of annexin-A1 positive mast cells in chronic granulomatous inflammation
Oliani SM, Ciocca GAP, Pimentel TA, Damazo AS, Gibbs L and Perretti M
Inflamm Res vol. 57 (10), 450-456.  
01-10-2008

Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles
Dalli J, Norling LV, Renshaw D, Cooper D, Leung KY and Perretti M
Blood vol. 112 (6), 2512-2519.  
15-09-2008

Annexin-A1: a pivotal regulator of the innate and adaptive immune systems
D'Acquisto F, Perretti M and Flower RJ
Brit J Pharmacol vol. 155 (2), 152-169.  
01-09-2008

Overview of the Role of Annexin 1 in the Innate and Adaptive Immune Response
D'Acquisto F and Perretti M
Immunology Endocrine & Metabolic Agents - Medicinal Chemistry, Bentham Science Publishers vol. 8 (3), 252-258.  
01-09-2008

Initial characterisation of the novel transgenic, the alx/fpr-rs2 null mouse
Dufton N, Buckingham J, Perretti M and Flower R
Fund Clin Pharmacol vol. 22, 48-48.  
01-08-2008

Novel insights into the inhibitory effects of Galectin-1 on neutrophil recruitment under flow
Cooper D, Norling LV and Perretti M
J Leukocyte Biol vol. 83 (6), 1459-1466.  
01-06-2008

Glucocorticoid treatment inhibits annexin-1 expression in rheumatoid arthritis CD4+ T cells.
D'Acquisto F, Paschalidis N, Raza K, Buckley CD, Flower RJ and Perretti M
Rheumatology (Oxford) vol. 47 (5), 636-639.  
01-05-2008

ENHANCED NEUTROPHIL EXPRESSION OF ANNEXIN-1 IN CORONARY ARTERY DISEASE
Sarndahl E, Bergstrom I, Nijm J, Perretti M and Jonasson L
Atherosclerosis Supp vol. 9 (1), 15-15.  
01-05-2008

Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function
Yona S, Lin HH, Dri P, Davies JQ, Hayhoe RPG, Lewis SM, Heinsbroek SEM, Brown KA, Perretti M, Hamann J, Treacher DF, Gordon S and Stacey M
Faseb J vol. 22 (3), 741-751.  
01-03-2008

Annexin-1 modulates repair of gastric mucosal injury
Martin GR, Perretti M, Flower RJ and Wallace JL
Am J Physiol-Gastr L vol. 294 (3), G764-G769.  
01-03-2008

Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking
Norling LV, Sampaio ALF, Cooper D and Perretti M
Faseb J vol. 22 (3), 682-690.  
01-03-2008

Butanol-extracted lipoteichoic acid induces in vivo leukocyte adhesion
Finney SJ, Anning PB, Cao TV, Perretti M, Evans TW and Burke-Gaffney A
Biochem Bioph Res Co vol. 364 (4), 831-837.  
28-12-2007

Aromatic lipoxin A(4) and lipoxin B-4 analogues display potent biological activities
O'Sullivan TP, Vallin KSA, Shah STA, Fakhry J, Maderna P, Scannell M, Sampaio ALF, Perretti M, Godson C and Guiry PJ
J Med Chem vol. 50 (24), 5894-5902.  
29-11-2007

Impaired T cell activation and increased Th2 lineage commitment in Annexin-1-deficient T cells
D'Acquisto F, Paschalidis N, Sampaio ALF, Merghani A, Flower RJ and Perretti M
Eur J Immunol vol. 37 (11), 3131-3142.  
01-11-2007

Annexin 1 cleavage in activated neutrophils - A pivotal role for proteinase 3
Vong L, D'Acquisto F, Pederzoli-Ribeil M, Lavagno L, Flower RJ, Witko-Sarsat R and Perretti M
J Biol Chem vol. 282 (41), 29998-30004.  
12-10-2007

Potential of calcitonin as a novel cotreatment for arthritis
Perretti M and Mancini L
International Journal of Clinical Rheumatology, Omics International vol. 2 (5), 493-496.  
01-10-2007

A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5.
Duchene J, Lecomte F, Ahmed S, Cayla C, Pesquero J, Bader M, Perretti M and Ahluwalia A
J Immunol vol. 179 (7), 4849-4856.  
01-10-2007

Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation.
Gavins FNE, Dalli J, Flower RJ, Granger DN and Perretti M
Faseb J vol. 21 (8), 1751-1758.  
01-06-2007

Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow.
Urquhart P, Rosignoli G, Cooper D, Motterlini R and Perretti M
J Pharmacol Exp Ther vol. 321 (2), 656-662.  
01-05-2007

Formyl peptide receptors and the regulation of ACTH secretion: targets for annexin A1, lipoxins, and bacterial peptides
John CD, Sahni V, Mehet D, Morris JF, Christian HC, Perretti M, Flower RJ, Solito E and Buckingham JC
Faseb J vol. 21 (4), 1037-1046.  
01-04-2007

Uneven modulation of the annexin 1 system in osteoblast-like cells by dexamethasone
Giner RM, Mancini L, Kamal AM and Perretti M
Biochem Bioph Res Co vol. 354 (2), 414-419.  
09-03-2007

Calcitonin and prednisolone display antagonistic actions on bone and have synergistic effects in experimental arthritis
Mancini L, Paul-Clark MJ, Rosignoli G, Hannon R, Martin JE, Macintyre I and Perretti M
Am J Pathol vol. 170 (3), 1018-1027.  
01-03-2007

Glucocorticoids in innate immunity: more transactivation than transrepression!
Perretti M
Blood vol. 109 (3), 852-853.  
01-02-2007

Resolution of inflammation: state of the art, definitions and terms
Serhan CN, Brain SD, Buckley CD, Gilroy DW, Haslett C, O'Neill LAJ, Perretti M, Rossi AG and Wallace JL
Faseb J vol. 21 (2), 325-332.  
01-02-2007

Annexin-1 modulates T-cell activation and differentiation.
D'Acquisto F, Merghani A, Lecona E, Rosignoli G, Raza K, Buckley CD, Flower RJ and Perretti M
Blood vol. 109 (3), 1095-1102.  
01-02-2007

[D-Trp(8)]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse)
Getting SJ, Lam CW, Leoni G, Gavins FNE, Grieco P and Perretti M
Mol Pharmacol vol. 70 (6), 1850-1855.  
01-12-2006

Glucocorticoid upregulation of the annexin-A1 receptor in leukocytes.
Sawmynaden P and Perretti M
Biochem Biophys Res Commun vol. 349 (4), 1351-1355.  
03-11-2006

Therapeutic Exploitation of Endogenous Anti-Inflammatory Mechanisms:Old and New Leads
Renshaw D, Urquhart P and Perretti M
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, Bentham Science Publishers vol. 5 (4), 289-305.  
01-11-2006

Melanocortin 3 receptors control crystal-induced inflammation
Getting SJ, Lam CW, Chen AS, Grieco P and Perretti M
Faseb J vol. 20 (13), 2234-2241.  
01-11-2006

Antiflammin-2 activates the human formyl-peptide receptor like 1.
Kamal AM, Hayhoe RPG, Paramasivam A, Cooper D, Flower RJ, Solito E and Perretti M
Scientificworldjournal vol. 6, 1375-1384.  
25-10-2006

Anti-inflammatory and analgesic aspects of the annexin A1 system
Flower RJ, Ayoub S and Perretti M
Acta Pharmacol Sin vol. 27 (9), 1272-1272.  
01-09-2006

Immunomodulation The promises of immunopharmacology for the development of new drugs
Cassatella MA and Perretti M
Current Opinion in Pharmacology, Elsevier vol. 6 (4), 376-378.  
01-08-2006

Annexin 1, anti-inflammatory drugs and the neuroendocrine-immune interface.
Flower RJ, Perretti M, D'Acquisto F and Buckingham JC
Acta Pharmacol Sin vol. 27, 13-14.  
01-07-2006

Impaired phagocytic mechanism in annexin 1 null macrophages
Yona S, Heinsbroek SEM, Peiser L, Gordon S, Perretti M and Flower RJ
Brit J Pharmacol vol. 148 (4), 469-477.  
01-06-2006

Novel aspects of annexin 1 and glucocorticoid biology: intersection with nitric oxide and the lipoxin receptor.
Perretti M and D'Acquisto F
Inflamm Allergy Drug Targets vol. 5 (2), 107-114.  
01-04-2006

Interaction of human neutrophils with endothelial cells regulates the expression of endogenous proteins annexin 1, galectin-1 and galectin-3
Gil CD, La M, Perretti M and Oliani SM
Cell Biol Int vol. 30 (4), 338-344.  
01-04-2006

Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis
Damazo AS, Yona S, Flower RJ, Perretti M and Oliani SM
J Immunol vol. 176 (7), 4410-4418.  
01-04-2006

Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement
Hayhoe RPG, Kamal AM, Solito E, Flower RJ, Cooper D and Perretti M
Blood vol. 107 (5), 2123-2130.  
01-03-2006

The melanocortin peptide HP228 displays protective effects in acute models of inflammation and organ damage
Getting SJ, Di Filippo C, D'Amico M and Perretti M
Eur J Pharmacol vol. 532 (1-2), 138-144.  
17-02-2006

Melanocortin receptor signaling in RAW264.7 macrophage cell line.
Lam CW, Perretti M and Getting SJ
Peptides vol. 27 (2), 404-412.  
01-02-2006

Inflammation-induced modulation of cellular galectin-1 and –3 expression in a model of rat peritonitis
Perretti M, COOPER D, Gil CD, Oliani SM and Rosignoli G
Inflammation Research vol. 55 (3), 99-107.  
01-01-2006

Annexin I regulates SKCO-15 cell invasion by signaling through formyl peptide receptors
PERRETTI M, Nusrat A, Akyildiz A, Parkos CA, Babbin BA, Lee WY and Winfree LM
J Biol Chem vol. 281, 19588-19599.  
01-01-2006

Ligand-specific glucocorticoid receptor activation in human platelets.
Moraes LA, Paul-Clark MJ, Rickman A, Flower RJ, Goulding NJ and Perretti M
Blood vol. 106 (13), 4167-4175.  
15-12-2005

Down-regulation of the anti-inflammatory protein annexin A1 in cystic fibrosis knock-out mice and patients
Bensalem N, Ventura AP, Vallee B, Lipecka J, Tondelier D, Davezac N, Dos Santos A, Perretti M, Fajac A, Sermet-Gaudelus I, Renouil M, Lesure JF, Halgand F, Laprevote O and Edelman A
Mol Cell Proteomics vol. 4 (10), 1591-1601.  
01-10-2005

Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro.
Chatterjee BE, Yona S, Rosignoli G, Young RE, Nourshargh S, Flower RJ and Perretti M
J Leukoc Biol vol. 78 (3), 639-646.  
01-09-2005

Aspirin and steroids: new mechanistic findings and avenues for drug discovery
Gilroy DW and Perretti M
Curr Opin Pharmacol vol. 5 (4), 405-411.  
01-08-2005

A novel role for Annexin 1 in macrophage phagocytosis
Yona S, Heinsbroek S, Gordon S, Perretti M and Flower RJ
Inflamm Res vol. 54, S217-S218.  
01-08-2005

Role of the immune system in chronic pain
Marchand F, Perretti M and McMahon SB
Nat Rev Neurosci vol. 6 (7), 521-532.  
01-07-2005

Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation
Damazo AS, Yona S, D'Acquisto F, Flower RJ, Oliani SM and Perretti M
Am J Pathol vol. 166 (6), 1607-1617.  
01-06-2005

Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasone-treated macrophages and annexin-derived peptide AC(2-26)
Maderna P, Yona S, Perretti M and Godson C
J Immunol vol. 174 (6), 3727-3733.  
15-03-2005

Controlling inflammation: a fat chance?
Flower RJ and Perretti M
J Exp Med vol. 201 (5), 671-674.  
07-03-2005

An overview of the effects of annexin 1 on cells involved in the inflammatory process.
Kamal AM, Flower RJ and Perretti M
Mem Inst Oswaldo Cruz vol. 100 Suppl 1, 39-47.  
01-03-2005

Annexin-1 is an endogenous gastroprotective factor against indomethacin-induced damage
Zanardo RCO, Perretti M and Wallace JL
Am J Physiol-Gastr L vol. 288 (3), G481-G486.  
01-03-2005

Inhibitory control of TGF-beta 1 on the activation of Rap1, CD11b, and transendothelial migration of leukocytes
Basoni C, Nobles M, Grimshaw A, Desgranges C, Davies D, Perretti M, Kramer IM and Genot E
Faseb J vol. 19 (3), 822-+.  
01-03-2005

In vitro and in vivo induction of heme oxygenase 1 in mouse macrophages following melanocortin receptor activation
Lam CW, Getting SJ and Perretti M
J Immunol vol. 174 (4), 2297-2304.  
15-02-2005

Macrophage biology in the Anx-A1-/- mouse.
Yona S, Ward B, Buckingham JC, Perretti M and Flower RJ
Prostaglandins Leukot Essent Fatty Acids vol. 72 (2), 95-103.  
01-02-2005

A novel effect for annexin 1-derived peptide ac2-26: reduction of allergic inflammation in the rat.
Flower RJ, PERRETTI M, Diaz BL, Bandeira-Melo C, Martins MA, Carvalho VF, Silva PM, Jose PJ and Bonavita AG
J Pharmacol Exp Ther vol. 313 (3), 1416-1422.  
01-01-2005

A twist in anti-inflammation: annexin 1 acts via the lipoxin A4 receptor.
Gavins FNE, Sawmynaden P, Chatterjee BE and Perretti M
Prostaglandins Leukot Essent Fatty Acids vol. 73 (3-4), 211-219.  
01-01-2005

The inhibition of neutrophil-endothelial cell adhesion by hyaluronan independent of CD44.
Alam CAS, Seed MP, Freemantle C, Brown J, Perretti M, Carrier M, Divwedi A, West DC, Gustafson S, Colville-Nash PR and Willoughby DA
Inflammopharmacology vol. 12 (5-6), 535-550.  
01-01-2005

Formyl-peptide receptor is not involved in the protection afforded by annexin 1 in murine acute myocardial infarct.
Gavins FNE, Kamal AM, D'Amico M, Oliani SM and Perretti M
Faseb J vol. 19 (1), 100-102.  
01-01-2005

Inhibitory effects of TSG-6 link module on leukocyte-endothelial cell interactions in vitro and in vivo
Cao TV, La M, Getting SJ, Day AJ and Perretti M
Microcirculation vol. 11 (7), 615-624.  
01-10-2004

MC-3 receptor and the inflammatory mechanisms activated in acute myocardial infarct
Getting SJ, Di Filippo C, Christian HC, Lam CW, Rossi F, D'Amico M and Perretti M
J Leukocyte Biol vol. 76 (4), 845-853.  
01-10-2004

The distinct alterations produced in cardiovascular functions by prednisolone and nitro-prednisolone (NCX-1015) in the rat highlight a causal role for endothelin-1
Di Filippo C, Rossi F, Ongini E, Del Soldato P, Perretti M and D'Amico M
J Pharmacol Exp Ther vol. 310 (3), 1133-1141.  
01-09-2004

Stimulus-specific defect in the phagocytic pathways of annexin 1 null macrophages.
Yona S, Buckingham JC, Perretti M and Flower RJ
Br J Pharmacol vol. 142 (5), 890-898.  
01-07-2004

Annexin 1 and the biology of the neutrophil.
Perretti M and Flower RJ
J Leukoc Biol vol. 76 (1), 25-29.  
01-07-2004

The Annexin 1-/- Mouse: Phenotypic Studies
MARTIN JE, Flower RJ, Perretti M, Hannon R, Getting SJ, Gavins FNE, Christian HC, Parente L, Paul-Clark MJ, Yona S, Oliani SM, Wells D, Cover PO, John CD, Solito E, Morris JF, Buckingham JC, Wells K, Liu K, Croxtall JD and Damazo AS
Annexins vol. 1 (2), 109-120.  
01-07-2004

Annexin 1 and neutrophil apoptosis
Perretti M and Solito E
Biochemical Society Transactions vol. 32, 507-510.  
01-06-2004

Stimulus-dependent specificity for annexin 1 inhibition of the inflammatory nociceptive response: the involvement of the receptor for formylated peptides
Pieretti S, Di Giannuario A, De Felice M, Perretti M and Cirino G
Pain vol. 109 (1-2), 52-63.  
01-05-2004

Inflammatory resolution: new opportunities for drug discovery.
Gilroy DW, Lawrence T, Perretti M and Rossi AG
Nat Rev Drug Discov vol. 3 (5), 401-416.  
01-05-2004

Neutrophil elastase (NE)-deficient mice demonstrate a nonredundant role for NE in neutrophil migration, generation of proinflammatory mediators, and phagocytosis in response to zymosan particles in vivo
Young RE, Thompson RD, Larbi KY, La M, Roberts CE, Shapiro SD, Perretti M and Nourshargh S
J Immunol vol. 172 (7), 4493-4502.  
01-04-2004

Modulation of inflammation and response to dexamethasone by annexin 1 in antigen-induced arthritis
Yang YH, Morand EF, Getting SJ, Paul-Clark M, Liu DL, Yona S, Hannon R, Buckingham JC, Perretti M and Flower RJ
Arthritis Rheum vol. 50 (3), 976-984.  
01-03-2004

Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment
Ahluwalia A, Foster P, Scotland RS, McLean PG, Mathur A, Perretti M, Moncada S and Hobbs AJ
P Natl Acad Sci Usa vol. 101 (5), 1386-1391.  
03-02-2004

Synthesis of nitro esters of prednisolone, new compounds combining pharmacological properties of both glucocorticoids and nitric oxide
Baraldi PG, Romagnoli R, Nunez MD, Perretti M, Paul-Clark MJ, Ferrario M, Govoni M, Benedini F and Ongini E
J Med Chem vol. 47 (3), 711-719.  
29-01-2004

An isocratic HPLC method for the quantitation of eicosanoids in human platelets
Moraes LA, Giner RM, Paul-Clark MJ, Perretti M and Perrett D
Biomed Chromatogr vol. 18 (1), 64-68.  
01-01-2004

Analysis of annexin 1 expression in rat trachea: study of mast cell heterogeneity.
PERRETTI M, Oliani SM, Takahashi HK, Damazo AS, Paul-Clark MJ and Straus AH
Annexins vol. 1, 12-18.  
01-01-2004

The annexin 1 receptor(s): is the plot unravelling?
Perretti M
Trends Pharmacol Sci vol. 24 (11), 574-579.  
01-11-2003

A novel biological activity for galectin-1 - Inhibition of leukocyte-endothelial cell interactions in experimental inflammation
La M, Cao TV, Cerchiaro G, Chilton K, Hirabayashi J, Kasao K, Oliani SM, Chernajovsky Y and Perretti M
Am J Pathol vol. 163 (4), 1505-1515.  
01-10-2003

Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands
Paul-Clark MJ, Roviezzo F, Flower RJ, Cirino G, Del Soldato P, Adcock IM and Perretti M
J Immunol vol. 171 (6), 3245-3252.  
15-09-2003

Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides
Getting SJ, Schioth HB and Perretti M
J Pharmacol Exp Ther vol. 306 (2), 631-637.  
01-08-2003

A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils
Solito E, Kamal A, Russo-Marie F, Buckingham JC, Marullo S and Perretti M
Faseb J vol. 17 (9), 1544-+.  
01-06-2003

Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms.
Gavins FNE, Yona S, Kamal AM, Flower RJ and Perretti M
Blood vol. 101 (10), 4140-4147.  
15-05-2003

Generation of innovative anti-inflammatory and anti-arthritic glucocorticoid derivatives that release NO: the nitro-steroids
Perretti M, Paul-Clark MJ, Mancini L and Flower RJ
Digest Liver Dis vol. 35, S41-S48.  
01-05-2003

Annexin 1: an endogenous anti-inflammatory protein.
Perretti M and Gavins FNE
News Physiol Sci vol. 18, 60-64.  
01-04-2003

Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: Studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor
Getting SJ, Christian HC, Lam CW, Gavins FNE, Flower RJ, Schioth HB and Perretti M
J Immunol vol. 170 (6), 3323-3330.  
15-03-2003

Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse.
Hannon R, Croxtall JD, Getting SJ, Roviezzo F, Yona S, Paul-Clark MJ, Gavins FNE, Perretti M, Morris JF, Buckingham JC and Flower RJ
Faseb J vol. 17 (2), 253-255.  
01-02-2003

Advances in the pathophysiology of constitutive and inducible cyclooxygenases: two enzymes in the spotlight.
PERRETTI M and Parente L
Biochemical Pharmacology vol. 65 (2), 153-159.  
01-01-2003

Migration of specific leukocyte subsets in response to cytokine or chemokine application in vivo.
Perretti M and Getting SJ
139-146.  
01-01-2003

Migration of Specific Leukocyte Subsets in Response to Cytokine or Chemokine Application In Vivo
Perretti M and Getting SJ
In Inflammation Protocols, Springer Nature 139-146.  
01-01-2003

The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner.
Getting SJ, Mahoney DJ, Cao T, Rugg MS, Fries E, Milner CM, Perretti M and Day AJ
J Biol Chem vol. 277 (52), 51068-51076.  
27-12-2002

NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice
Fiorucci S, Antonelli E, Distrutti E, Del Soldato P, Flower RJ, Clark MJP, Morelli A, Perretti M and Ignarro LJ
P Natl Acad Sci Usa vol. 99 (24), 15770-15775.  
26-11-2002

Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor.
Perretti M, Chiang N, La M, Fierro IM, Marullo S, Getting SJ, Solito E and Serhan CN
Nat Med vol. 8 (11), 1296-1302.  
01-11-2002

Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis.
Getting SJ, Christian HC, Flower RJ and Perretti M
Arthritis Rheum vol. 46 (10), 2765-2775.  
01-10-2002

Annexin 1 modulates monocyte-endothelial cell interaction in vitro and cell migration in vivo in the human SCID mouse transplantation model.
Perretti M, Ingegnoli F, Wheller SK, Blades MC, Solito E and Pitzalis C
J Immunol vol. 169 (4), 2085-2092.  
15-08-2002

Time-dependent expression of annexin 1 in a model of chronic granulomatous inflammation
Gibbs L, Carollo MG, Damazo AS, Oliani SM and Perretti M
Inflamm Res vol. 51 (6), 300-306.  
01-06-2002

Stromal cell-derived factor 1 (CXCL12) induces human cell migration into human lymph nodes transplanted into SCID mice
Blades MC, Manzo A, Ingegnoli F, Taylor PR, Panayi GS, Irjala H, Jalkanen S, Haskard DO, Perretti M and Pitzalis C
J Immunol vol. 168 (9), 4308-4317.  
01-05-2002

Effects of cyclooxygenase-1/cyclooxygenase-2 inhibition on leukocyte/endothelial cell interactions in the rat mesentery
Calatayud S, Mitchell JA, Perretti M, Giuliano F and Warner TD
Eur J Pharmacol vol. 440 (1), 71-77.  
05-04-2002

Chemokines as novel therapeutic targets in inflammatory diseases
Ajuebor MN, Swain MG and Perretti M
Biochem Pharmacol vol. 63 (7), 1191-1196.  
01-04-2002

Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID mice
Blades MC, Ingegnoli F, Wheller SK, Manzo A, Wahid S, Panayi GS, Perretti M and Pitzalis C
Arthritis Rheum vol. 46 (3), 824-836.  
01-03-2002

A novel control mechanism based on GDNF modulation of somatostatin release from sensory neurones
Malcangio M, Getting S, Grist J, Cunningham JR, Bradbury EJ, Issa PC, Lever IJ, Pezet S and Perretti M
Faseb J vol. 16 (3), 730-+.  
01-03-2002

Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis
Paul-Clark MJ, Mancini L, Del Soldato P, Flower RJ and Perretti M
P Natl Acad Sci Usa vol. 99 (3), 1677-1682.  
05-02-2002

Annexin 1 localisation in tissue eosinophils as detected by electron microscopy.
PERRETTI M, Damazo AS and Oliani SM
Mediators of Inflammation. vol. 11, 287-292.  
01-01-2002

Role of cell migration in the pathogenesis of rheumatoid arthritis: in vivo studies in SCID mice transplanted with human synovial membrane
Ingegnoli F, Blades M, Manzo A, Wahid S, Perretti M, Panayi G and Pitzalis C
Reumatismo, Pagepress Publications vol. 54 (2), 128-132.  
01-01-2002

A novel control mechanism based on GDNF modulation of somatostatin release from sensory neurones.
Malcangio M, Getting SJ, Grist J, Cunningham JR, Bradbury EJ, Charbel Issa P, Lever IJ, Pezet S and Perretti M
The Faseb Journal : Official Publication of The Federation of American Societies For Experimental Biology vol. 16 (7), 730-732.  
01-01-2002

Stromal cell derived factor-1 (CXCL 12) induces monocyte migration into human synovium transplanted onto SCID mice.
PERRETTI M, Manzo A, Wheller SK, Ingegnoli F, Blades MC, Petzalis C, Wahid S and Panayi GS
Arth Rheum vol. 46, 824-836.  
01-01-2002

Contrasting roles for RANTES and macrophage inflammatory protein-1α (MIP-1α) in a murine model of allergic peritonitis
Das AM, Ajuebor MN, Flower RJ, Perretti M and Mccoll SR
Clinical & Experimental Immunology, Oxford University Press (Oup) vol. 117 (2), 223-229.  
24-12-2001

Analysis of the temporal expression of chemokines and chemokine receptors during experimental granulomatous inflammation: role and expression of MIP-1alpha and MCP-1.
Carollo M, Hogaboam CM, Kunkel SL, Delaney S, Christie MI and Perretti M
Br J Pharmacol vol. 134 (6), 1166-1179.  
01-11-2001

Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase
Mabley JG, Jagtap P, Perretti M, Getting SJ, Salzman AL, Virag L, Szabo E, Soriano FG, Liaudet L, Abdelkarim GE, Hasko G, Marton A, Southan GJ and Szabo C
Inflamm Res vol. 50 (11), 561-569.  
01-11-2001

Analysis of the protection afforded by annexin 1 in ischaemia-reperfusion injury: focus on neutrophil recruitment.
La M, Tailor A, D'Amico M, Flower RJ and Perretti M
Eur J Pharmacol vol. 429 (1-3), 263-278.  
19-10-2001

Cytokine modulation of liver annexin 1 expression during experimental endotoxemia
de Coupade C, Ajuebor MN, Russo-Marie F, Perretti M and Solito E
Am J Pathol vol. 159 (4), 1435-1443.  
01-10-2001

Pharmacological modulation of allergic inflammation in the rat airways and association with mast cell heterogeneity
Damazo AS, de Lima WT, Perretti M and Oliani SM
Eur J Pharmacol vol. 426 (1-2), 123-130.  
24-08-2001

Arthritic diseases: melanocortin type 3 receptor agonists as potential therapeutics.
Getting SJ and Perretti M
Current Opinion in Investigational Drugs vol. 2 (8), 1064-1069.  
01-08-2001

The use of lymphocyte function-associated antigen (LFA)-1-deficient mice to determine the role of LFA-1, Mac-1, and alpha 4 integrin in the inflammatory response of neutrophils
Henderson RB, Lim LHK, Tessier PA, Gavins FNE, Mathies M, Perretti M and Hogg N
J Exp Med vol. 194 (2), 219-226.  
16-07-2001

Involvement of the receptor for formylated peptides in the in vivo anti-migratory actions of annexin 1 and its mimetics
Perretti M, Getting SJ, Solito E, Murphy PM and Gao JL
Am J Pathol vol. 158 (6), 1969-1973.  
01-06-2001

Enhanced serum glucocorticoid levels mediate the reduction of serosal mast cell numbers in diabetic rats
Diaz B, Barreto E, Cordeiro R, Perretti M, Martins M and Silva P
Life Sci vol. 68 (26), 2925-2932.  
18-05-2001

Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation
Solito E, de Coupade C, Canaider S, Goulding NJ and Perretti M
Brit J Pharmacol vol. 133 (2), 217-228.  
01-05-2001

Development of a new model to investigate lymphocyte migration into human peripheral lymph nodes (HPLN) transplanted into SCID mice
Blades MC, Ingegnoli F, Manzo A, Wahid S, Haskard D, Panayi G, Perretti M and Pitzalis C
Rheumatology vol. 40, 66-66.  
01-04-2001

Neutrophil interaction with inflamed postcapillary venule endothelium alters annexin 1 expression
Oliani SM, Paul-Clark MJ, Christian HC, Flower RJ and Perretti M
Am J Pathol vol. 158 (2), 603-615.  
01-02-2001

Mechanism of Reaction of Melatonin with Human Myeloperoxidase.
PERRETTI M, Obinger C, Furtmuller PG, Allegra M, Regelsberger G, Livrea MA, Tesoriere L and Turco-Leveri ML
Biochem Biophys Res Commun. vol. 282, 380-386.  
01-01-2001

Morphological alteration of peritoneal mast cells and macrophages in the mouse peritoneal cavity during the early phases of an allergic inflammatory reaction
Oliani SM, Lim LHK, Christian HC, Pell K, Das AM and Perretti M
Cell Biol Int vol. 25 (8), 795-803.  
01-01-2001

Glucocorticoids and leukocyte adhesion
Pitzalis C, Pipitone N and Perretti M
In Glucocorticoids, Springer Nature 105-118.  
01-01-2001

Neutrophil accumulation induced by bacterial lipopolysaccharide: effects of dexamethasone and annexin 1
Allcock GH, Allegra M, Flower RJ and Perretti M
Clin Exp Immunol vol. 123 (1), 62-67.  
01-01-2001

Natural and synthetic agonists of the melanocortin receptor type 3 possess anti-inflammatory properties.
Getting SJ, Allcock GH, Flower R and Perretti M
J Leukoc Biol vol. 69 (1), 98-104.  
01-01-2001

Modulation of the effects of osteoprotegerin (OPG) ligand in a human leukemic cell line by OPG and calcitonin
Mancini L, Moradi-Bidhendi N, Brandi ML, Perretti M and MacIntyre I
Biochem Bioph Res Co vol. 279 (2), 391-397.  
20-12-2000

21‐NO‐prednisolone is a novel nitric oxide‐releasing derivative of prednisolone with enhanced anti‐inflammatory properties
Paul‐Clark M, Del Soldato P, Fiorucci S, Flower RJ and Perretti M
British Journal of Pharmacology, Wiley vol. 131 (7), 1345-1354.  
01-12-2000

Kinin B1 receptors and the cardiovascular system: regulation of expression and function
McLean PG, Perretti M and Ahluwalia A
Cardiovascular Research, Oxford University Press (Oup) vol. 48 (2), 194-210.  
01-11-2000

Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocyte recruitment.
D'Amico M, Di Filippo C, La M, Solito E, McLean PG, Flower RJ, Oliani SM and Perretti M
Faseb J vol. 14 (13), 1867-1869.  
01-10-2000