Publications

Publications of specific relevance to Predictive in vitro Models
2020

Sheikh MH, Henson S, Loiola RA, Mercurio S, Colamatteo A, Maniscalco GT, De Rosa V,
Mcarthur S and
Solito E (2020).
Immuno-metabolic impact of the multiple sclerosis patients’ sera on endothelial cells of the blood-brain barrier. Biomed Central Journal of Neuroinflammation 10.1186/s12974-020-01810-8
McArthur S, Juban G, Gobbetti T, Desgeorges T, Theret M, Gondin J, Toller-Kawahisa JE, Reutelingsperger CP, Chazaud B,
Perretti M and Mounier R (2020).
Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation. Journal of Clinical Investigation vol. 130, (3) 1156-1167.
10.1172/JCI124635
Wickstead ES, Karim HA, Manuel RE, Biggs CS, Getting SJ and
McArthur S (2020).
Reversal of β-Amyloid-Induced Microglial Toxicity In Vitro by Activation of Fpr2/3. Oxid Med Cell Longev vol. 2020,
10.1155/2020/21391922019

Lopez Tremoleda J, Wall J, Naganathar V, Praditsuktavorn B, Bugg O,
Mcarthur S, Thiemermann C and Brohi K (2019).
Modelling cardiac dysfunction following traumatic haemorrhage injury: impact on myocardial integrity. Frontiers Media Frontiers in Immunology vol. 10,
10.3389/fimmu.2019.02774
Wan H, Li X, Ahmad U, Huang Y, Uttagomol J, Rehman A, Zhou K, Warnes G,
Mcarthur S and
Parkinson E (2019).
Desmoglein-3 acts as a pro-survival protein by suppressing reactive oxygen species and doming whilst augmenting the tight junctions in MDCK cells. Elsevier Mechanisms of Ageing and Development 10.1016/j.mad.2019.111174
Loiola RA, Wickstead ES,
Solito E and
Mcarthur S (2019).
Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Frontiers Media Frontiers in Endocrinology 10.3389/fendo.2019.00420
Loiola RA, Wickstead ES,
Solito E and
McArthur S (2019).
Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Front Endocrinol (Lausanne) vol. 10,
10.3389/fendo.2019.004202018

Barrios-Silva LV, Parnell M, Shinwari ZB, Chaudhary GA, Xenofontos T, van Bekhoven A,
MCARTHUR S and Elliott BT (2018).
Activin sub-family peptides predict chronological age in humans. Wiley Physiological Reports vol. 6, (17) e13823-e13823.
10.14814/phy2.13823
Hoyles L, Snelling T, Umlai U-K, Nicholson JK, Carding SR, Glen RC and
MCARTHUR S (2018).
Microbiome-host systems interactions: Protective effects of propionate upon the bloodbrain barrier. Biomed Central Bmc Microbiome vol. 6, 55-55.
10.1186/s40168-018-0439-y2016

Virdee K, Kentrop J, Jupp B, Venus B, Hensman D,
McArthur S, Wilkinson J, Robbins TW, Gillies G and Dalley JW (2016).
Counteractive effects of antenatal glucocorticoid treatment on D1 receptor modulation of spatial working memory. Psychopharmacology (Berl) vol. 233, (21-22) 3751-3761.
10.1007/s00213-016-4405-8
McArthur S, Loiola RA, Maggioli E, Errede M, Virgintino D and
SOLITO E (2016).
The restorative role of annexin A1 at the blood–brain barrier. Biomed Central Fluids and Barriers of The Cns vol. 13, (17)
10.1186/s12987-016-0043-0
McArthur S, Pienaar IS, Siddiqi SM and Gillies GE (2016).
Sex-specific disruption of murine midbrain astrocytic and dopaminergic developmental trajectories following antenatal GC treatment. Brain Struct Funct vol. 221, (5) 2459-2475.
10.1007/s00429-015-1049-0
Maggioli E, McArthur S, Mauro C, Kieswich J, Kusters DHM, Reutelingsperger CPM, Yaqoob M and
Solito E (2016).
Estrogen protects the blood–brain barrier from inflammation-induced disruption and increased lymphocyte trafficking. Brain, Behavior, and Immunity vol. 51, 212-222.
10.1016/j.bbi.2015.08.0202015

Shende VH, McArthur S, Gillies GE and Opacka-Juffry J (2015).
Astroglial Plasticity Is Implicated in Hippocampal Remodelling in Adult Rats Exposed to Antenatal Dexamethasone. Neural Plast vol. 2015,
10.1155/2015/694347
McArthur S, Gobbetti T, Kusters DHM, Reutelingsperger CP, Flower RJ and
Perretti M (2015).
Definition of a novel pathway centered on lysophosphatidic acid to recruit monocytes during the resolution phase of tissue inflammation. Journal of Immunology vol. 195, (3) 1139-1151.
10.4049/jimmunol.15007332014

Gobbetti T, Coldewey SM, Chen J, McArthur S, Le Faouder P, Cenac N, Flower RJ, Thiemermann C and
Perretti M (2014).
Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis. Proceedings of The National Academy of Sciences of The United States of America vol. 111, (52) 18685-18690.
10.1073/pnas.1410938111
Thompson D, McArthur S, Hislop JN, Flower RJ and
Perretti M (2014).
Identification of a novel recycling sequence in the C-tail of FPR2/ALX receptor: association with cell protection from apoptosis. J Biol Chem vol. 289, (52) 36166-36178.
10.1074/jbc.M114.612630
Gillies GE, Virdee K, McArthur S and Dalley JW (2014).
Sex-dependent diversity in ventral tegmental dopaminergic neurons and developmental programing: A molecular, cellular and behavioral analysis. Neuroscience vol. 282, 69-85.
10.1016/j.neuroscience.2014.05.033
Locatelli I, Sutti S, Jindal A, Vacchiano M, Bozzola C, Reutelingsperger C, Kusters D, Bena S, Parola M, Paternostro C, Bugianesi E, McArthur S, Albano E and
Perretti M (2014).
Endogenous Annexin A1 Is a Novel Protective Determinant in Nonalcoholic Steatohepatitis in Mice. Hepatology vol. 60, (2) 531-544.
10.1002/hep.27141
Virdee K, McArthur S, Brischoux F, Caprioli D, Ungless MA, Robbins TW, Dalley JW and Gillies GE (2014).
Antenatal glucocorticoid treatment induces adaptations in adult midbrain dopamine neurons, which underpin sexually dimorphic behavioral resilience. Neuropsychopharmacology vol. 39, (2) 339-350.
10.1038/npp.2013.1962013

Cooray SN, Gobbetti T, Montero-Melendez T, McArthur S, Thompson D, Clark AJL, Flower RJ and
Perretti M (2013).
Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proc Natl Acad Sci U S A vol. 110, (45) 18232-18237.
10.1073/pnas.1308253110
Cash JL, Bena S, Headland SE, McArthur S, Brancaleone V and
Perretti M (2013).
Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. Embo Rep vol. 14, (11) 999-1007.
10.1038/embor.2013.138
Nadkarni S and McArthur S (2013).
Oestrogen and immunomodulation: new mechanisms that impact on peripheral and central immunity. Curr Opin Pharmacol vol. 13, (4) 576-581.
10.1016/j.coph.2013.05.007
Katsouri L, Vizcaychipi MP, McArthur S, Harrison I, Suárez-Calvet M, Lleo A, Lloyd DG, Ma D and Sastre M (2013).
Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease. Neurobiol Aging vol. 34, (4) 1105-1115.
10.1016/j.neurobiolaging.2012.09.010
Cristante E, McArthur S, Mauro C, Maggioli E, Romero IA, Wylezinska-Arridge M, Couraud PO, Lopez-Tremoleda J, Christian HC, Weksler BB, Malaspina A and
Solito E (2013).
Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications. Proc Natl Acad Sci U S A vol. 110, (3) 832-841.
10.1073/pnas.12093621102012

Dalli J, Montero-Melendez T, McArthur S and
Perretti M (2012).
Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Front Pharmacol vol. 3,
10.3389/fphar.2012.000282011

McArthur S, Robinson IC and Gillies GE (2011).
Novel ontogenetic patterns of sexual differentiation in arcuate nucleus GHRH neurons revealed in GHRH-enhanced green fluorescent protein transgenic mice. Endocrinology vol. 152, (2) 607-617.
10.1210/en.2010-0798
McArthur S and Gillies GE (2011).
Peripheral vs. Central Sex Steroid Hormones in Experimental Parkinson's Disease. Front Endocrinol (Lausanne) vol. 2,
10.3389/fendo.2011.000822010

McArthur S, Cristante E, Paterno M, Christian H, Roncaroli F, Gillies GE and
Solito E (2010).
Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. J Immunol vol. 185, (10) 6317-6328.
10.4049/jimmunol.1001095
Gillies GE and McArthur S (2010).
Estrogen actions in the brain and the basis for differential action in men and women: a case for sex-specific medicines. Pharmacol Rev vol. 62, (2) 155-198.
10.1124/pr.109.002071
Gillies GE and McArthur S (2010).
Independent influences of sex steroids of systemic and central origin in a rat model of Parkinson's disease: A contribution to sex-specific neuroprotection by estrogens. Horm Behav vol. 57, (1) 23-34.
10.1016/j.yhbeh.2009.06.0022009

McArthur S, Yazid S, Christian H, Sirha R, Flower R, Buckingham J and
Solito E (2009).
Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization. Faseb J vol. 23, (11) 4000-4010.
10.1096/fj.09-131391
Yazid S,
Solito E, Christian H, McArthur S, Goulding N and Flower R (2009).
Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1. Biochem Pharmacol vol. 77, (12) 1814-1826.
10.1016/j.bcp.2009.03.0102008
McArthur S, Prasongchean W, Gillies G and
Solito E (2008).
A critical role for the anti-inflammatory protein annexin A1 in microglial phagocytosis. Fund Clin Pharmacol vol. 22, 23-23.
Solito E, McArthur S, Christian H, Gavins F, Buckingham JC and Gillies GE (2008).
Annexin A1 in the brain--undiscovered roles? Trends Pharmacol Sci vol. 29, (3) 135-142.
10.1016/j.tips.2007.12.0032007

McArthur S, McHale E and Gillies GE (2007).
The size and distribution of midbrain dopaminergic populations are permanently altered by perinatal glucocorticoid exposure in a sex- region- and time-specific manner. Neuropsychopharmacology vol. 32, (7) 1462-1476.
10.1038/sj.npp.1301277
McArthur S, Murray HE, Dhankot A, Dexter DT and Gillies GE (2007).
Striatal susceptibility to a dopaminergic neurotoxin is independent of sex hormone effects on cell survival and DAT expression but is exacerbated by central aromatase inhibition. J Neurochem vol. 100, (3) 678-692.
10.1111/j.1471-4159.2006.04226.x2006

McArthur S, Siddique Z-L, Christian HC, Capone G, Theogaraj E, John CD, Smith SF, Morris JF, Buckingham JC and Gillies GE (2006).
Perinatal glucocorticoid treatment disrupts the hypothalamo-lactotroph axis in adult female, but not male, rats. Endocrinology vol. 147, (4) 1904-1915.
10.1210/en.2005-14962005

McArthur S, McHale E, Dalley JW, Buckingham JC and Gillies GE (2005).
Altered mesencephalic dopaminergic populations in adulthood as a consequence of brief perinatal glucocorticoid exposure. J Neuroendocrinol vol. 17, (8) 475-482.
10.1111/j.1365-2826.2005.01331.x2004

Gillies GE, Murray HE, Dexter D and McArthur S (2004).
Sex dimorphisms in the neuroprotective effects of estrogen in an animal model of Parkinson's disease. Pharmacol Biochem Behav vol. 78, (3) 513-522.
10.1016/j.pbb.2004.04.022