Mr Simon König

Simon König

POSTDOCTORAL RESEARCH ASSOCIATE

School of Engineering and Materials Science
Queen Mary University of London
07721 651565
www.sems.qmul.ac.uk/staff/s.koenig/?fq=simon
ORCID Google Scholar LinkedIn

Research

Organ-on-a-Chip, Muskuloskeletal, Tendon, Mechanobiology, Vascularization, Microfluidics, Fluigent, Biomimix

Musculoskeletal Models

Interests

I am currently working on an MRC-funded project developing human tendon-on-a-chip technology. By combining human tissue samples with commercial organ-on-a-chip systems, we aim to create human-relevant, vascularised and mechanoactive models of tendon disease. This platform will help transform our understanding and treatment of tendinopathy—a painful and often chronic condition affecting millions worldwide.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2026

From guideline to practice: A single-center evaluation of the ‘action corridor’ model and generative AI for PET/CT quality management
Obolenski O, Hristova I, Munk OL, Shekari M, Holstensson M, Higuchi T, Stokke C, Goh V et al.
Eanm Innovation, Elsevier vol. 3 
01-06-2026

2025

Transferrin-Functionalized Liposomes Enhance MAPT-ASO Transport Across a 3D Blood–Brain Barrier Microvascular Network Model
Konig S, Shen X, Mantovani G, Winkler GS, Zhu Z, Moeendarbary E
International Journal of Molecular Sciences, Mdpi vol. 26 (23) 
24-11-2025
Mechanobiology of the blood-brain barrier during development, disease and ageing
Konig S, Jayarajan V, Wray S, Kamm R, Moeendarbary E
Nature Communications, Springer Nature vol. 16 (1) 
06-08-2025
Examining Stromal Cell Interactions in an In Vitro Blood–Brain Barrier Model with Human Umbilical Vein Endothelial Cells
Margari A, Konig S, Jayarajan V, Rizzato S, Maruccio G, Moeendarbary E
Cells, Mdpi vol. 14 (11) 
22-05-2025

2020

Cell culture dimensionality influences mesenchymal stem cell fate through cadherin-2 and cadherin-11
Passanha FR, Geuens T, Konig S, van Blitterswijk CA, LaPointe VL
Biomaterials, Elsevier vol. 254 
21-05-2020

Transferrin-Functionalized Liposomes Enhance Mapt-Aso Transport Across a 3D Blood-Brain Barrier Microvascular Network Model
Konig S, Shen X, Mantovani G, Winkler GS, Zhu Z, Moeendarbary E
In Preprints.Org 
Cell culture dimensionality influences mesenchymal stem cell fate through cadherin-2 and cadherin-11
Passanha FR, Geuens T, Konig S, van Blitterswijk CA, LaPointe VL
In Biorxiv