Prof Jesmond Dalli

Jesmond Dalli

Professor in Molecular Pharmacology

Barts and The London School of Medicine and Dentistry
jdallilab.com/
ORCiD

Research

Tissue repair and regeneration, Myelopoesis, resolution mechanisms, GPCR biology, innate immunity, lipid mediators

Cardiovascular Models, Infectious Disease and Inflammation Models, Musculoskeletal Models

Interests

My research interests are in understanding the biology of a novel class of essential fatty acid derived molecules termed as specilized pro-resolving mediators in regulating innate immunity and reparative mechanisms. We are developing and using new in vitro organ-chip models, including bone marrow and joint models, for understanding disease and testing potential therapeutics.

Publications

Publications of specific relevance to Predictive in vitro Models

2024

Walker ME, De Matteis R, Perretti M and Dalli J (2024). Resolvin T4 enhances macrophage cholesterol efflux to reduce vascular disease. Springer Nature  Nature Communications  vol. 15, (1) 10.1038/s41467-024-44868-1
Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR, Schmidt B, Dalli J, Greene ER, Gus-Brautbar Y, Piwowarski J, Mammoto T, Zurakowski D, Perretti M, Sukhatme VP, Kaipainen A, Kieran MW, Huang S and Panigrahy D (2024). Addendum: Resolvins suppress tumor growth and enhance cancer therapy. Rockefeller University Press  Journal of Experimental Medicine  vol. 221, (3) 10.1084/jem.2017068101232024a
Aguirre GA, Goulart MR, Bank BPT, Dalli J and Kocher HM (2024). Corrigendum: Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion. Frontiers  Frontiers in Immunology  vol. 15, 10.3389/fimmu.2024.1353835

2023

Koenis DS, de Matteis R, Rajeeve V, Cutillas P and Dalli J (2023). Efferocyte‐Derived MCTRs Metabolically Prime Macrophages for Continual Efferocytosis via Rac1‐Mediated Activation of Glycolysis. Wiley  Advanced Science  vol. 11, (7) 10.1002/advs.202304690
Chen J, Oggero S, Cecconello C, Dalli J, Hayat H, Hjiej Andaloussi A, Sanni S, Jonassen TE and Perretti M (2023). The Annexin-A1 mimetic RTP-026 promotes acute cardioprotection through modulation of immune cell activation. Elsevier  Pharmacological Research  vol. 198, 10.1016/j.phrs.2023.107005
Aguirre GA, Goulart MR, Bank BPT, Dalli J and Kocher HM (2023). Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion. Frontiers  Frontiers in Immunology  vol. 14, 10.3389/fimmu.2023.1248547
Dalli J and Gomez EA (2023). Reply to: Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples. Springer Nature  Nature Communications  vol. 14, (1) 10.1038/s41467-023-41767-9
Ervik K, Reinertsen AF, Koenis DS, Dalli J and Hansen TV (2023). Stereoselective Synthesis, Pro-resolution, and Anti-inflammatory Actions of RvD5n‑3 DPA. American Chemical Society (Acs)  Journal of Natural Products  vol. 86, (11) 2546-2553. 10.1021/acs.jnatprod.3c00769
Ramirez JL, de Almeida Oliveira G, Calvo E, Dalli J, Colas RA, Serhan CN, Ribeiro JM and Barillas-Mury C (2023). Author Correction: A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae. Springer Nature  Nature Communications  vol. 14, (1) 10.1038/s41467-023-39932-1
Laiglesia LM, Escoté X, Sáinz N, Felix-Soriano E, Santamaría E, Collantes M, Fernández-Galilea M, Colón-Mesa I, Martínez-Fernández L, Quesada-López T, Quesada-Vázquez S, Rodríguez-Ortigosa C, Arbones-Mainar JM, Valverde ÁM, Martínez JA, Dalli J, Herrero L, Lorente-Cebrián S, Villarroya F and Moreno-Aliaga MJ (2023). Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice. Elsevier  Molecular Metabolism  vol. 74, 10.1016/j.molmet.2023.101749
Mai NTH, Dobbs N, Phu NH, Colas RA, Thao LTP, Thuong NTT, Nghia HDT, Hanh NHH, Hang NT, Heemskerk AD, Day JN, Ly L, Thu DDA, Merson L, Kestelyn E, Wolbers M, Geskus R, Summers D, Chau NVV, Dalli J and Thwaites GE (2023). Correction: A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults. Elife  Elife  vol. 12, 10.7554/elife.87888
Dalli J, Kitch D, O'Brien MP, Hunt PW, Funderburg N, Moisi D, Gupta A, Brown TT, Tien PC, Aberg JA and Shivakoti R (2023). Pro-inflammatory and pro-resolving lipid mediators of inflammation in HIV: effect of aspirin intervention. Elsevier  Ebiomedicine  vol. 89, 10.1016/j.ebiom.2023.104468
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN and Perretti M (2023). Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis. American Society For Clinical Investigation  Jci Insight  vol. 8, (3) 10.1172/jci.insight.168728
Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC, Bansal J, Pitrola K, Shaw C, D'Acquisto F, Colas RA, Marelli-Berg F, Dalli J and Ahluwalia A (2023). Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans. American Society For Clinical Investigation  Journal of Clinical Investigation  vol. 133, (2) 10.1172/jci168068

2022

Flak MB, Koenis DS, Gonzalez-Nunez M, Chopo-Pizarro A and Dalli J (2022). Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation. Elsevier  Biochemical Pharmacology  vol. 207, 10.1016/j.bcp.2022.115348
del Campo LSD, García-Redondo AB, Rodríguez C, Zaragoza C, Duro-Sánchez S, Palmas F, de Benito-Bueno A, Socuéllamos PG, Peraza DA, Rodrigues-Díez R, Valenzuela C, Dalli J, Salaices M and Briones AM (2022). Resolvin D2 Attenuates Cardiovascular Damage in Angiotensin II-Induced Hypertension. Wolters Kluwer  Hypertension  vol. 80, (1) 84-96. 10.1161/hypertensionaha.122.19448
Silva RA, Domingos R, Trujillo M, Filho A, Oliveira C, Baldini R, Dalli J and Netto L (2022). LsfA, a 1-Cys Peroxiredoxin involved with Pseudomonas aeruginosa virulence: Structure, biochemical activity, and its influence in inflammation/resolution. Elsevier  Free Radical Biology and Medicine  vol. 192, 10.1016/j.freeradbiomed.2022.10.213
Flak MB, Colas RA, Muñoz-Atienza E, Curtis MA, Dalli J and Pitzalis C (2022). Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis. American Society For Clinical Investigation  Jci Insight  vol. 7, (20) 10.1172/jci.insight.165600
Perretti M and Dalli J (2022). Resolution Pharmacology: Focus on Pro-Resolving Annexin A1 and Lipid Mediators for Therapeutic Innovation in Inflammation. Annual Reviews  The Annual Review of Pharmacology and Toxicology  vol. 63, (1) 449-469. 10.1146/annurev-pharmtox-051821-042743
Caravaca AS, Gallina AL, Tarnawski L, Shavva VS, Colas RA, Dalli J, Malin SG, Hult H, Arnardottir H and Olofsson PS (2022). Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit. Proceedings of The National Academy of Sciences  Proceedings of The National Academy of Sciences of The United States of America  vol. 119, (22) 10.1073/pnas.2023285119
Sips M, Gerlo S, De Clercq L, Gomez EA, Colas RA, Dalli J and Vandekerckhove L (2022). Distinct immune profiles of HIV‐infected subjects are linked to specific lipid mediator signature. Wiley  Immunity Inflammation and Disease  vol. 10, (6) 10.1002/iid3.629
Pistorius K, Ly L, Souza PR, Gomez EA, Koenis DS, Rodriguez AR, Foster J, Sosabowski J, Hopkinson M, Rajeeve V, Spur BW, Pitsillides A, Pitzalis C and Dalli J (2022). MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis. Elsevier  Ebiomedicine  vol. 79, 10.1016/j.ebiom.2022.103974
Dyall SC, Balas L, Bazan NG, Brenna JT, Chiang N, da Costa Souza F, Dalli J, Durand T, Galano J-M, Lein PJ, Serhan CN and Taha AY (2022). Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions. Elsevier  Progress in Lipid Research  vol. 86, 10.1016/j.plipres.2022.101165
Dalli J, Gomez EA and Jouvene CC (2022). Utility of the Specialized Pro-Resolving Mediators as Diagnostic and Prognostic Biomarkers in Disease. Mdpi  Biomolecules  vol. 12, (3) 10.3390/biom12030353
Mikroulis A, Ledri M, Ruffolo G, Palma E, Sperk G, Dalli J, Vezzani A and Kokaia M (2022). Lipid mediator n‐3 docosapentaenoic acid‐derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G‐protein‐coupled receptor. Wiley  The Faseb Journal  vol. 36, (3) 10.1096/fj.202101815r
Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Moreira SAM, Rathod K, Chen J, Bubb K, Colas R, Khambata RS, Dalli J and Ahluwalia A (2022). 20‐hydroxyeicosatetraenoic acid (20‐HETE) is a pivotal endogenous ligand for TRPV1‐mediated neurogenic inflammation in the skin. Wiley  British Journal of Pharmacology  vol. 179, (7) 1450-1469. 10.1111/bph.15726
De Matteis R, Flak MB, Gonzalez-Nunez M, Austin-Williams S, Palmas F, Colas RA and Dalli J (2022). Aspirin activates resolution pathways to reprogram T cell and macrophage responses in colitis-associated colorectal cancer. American Association For The Advancement of Science (Aaas)  Science Advances  vol. 8, (5) 10.1126/sciadv.abl5420
Kraft JD, Blomgran R, Bergström I, Soták M, Clark M, Rani A, Rajan MR, Dalli J, Nyström S, Quiding‐Järbrink M, Bromberg J, Skoog P and Börgeson E (2022). Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis. Wiley  The Faseb Journal  vol. 36, (3) 10.1096/fj.202101219rr

2021

Reinertsen AF, Primdahl KG, De Matteis R, Dalli J and Hansen TV (2021). Stereoselective Synthesis, Configurational Assignment and Biological Evaluations of the Lipid Mediator RvD2n‐3 DPA. Wiley  Chemistry - a European Journal  vol. 28, (7) 10.1002/chem.202103857
Beegun I, Koenis DS, Alusi G and Dalli J (2021). Dysregulated Maresin Concentrations in Plasma and Nasal Secretions From Patients With Chronic Rhinosinusitis. Frontiers  Frontiers in Immunology  vol. 12, 10.3389/fimmu.2021.733019
Palmas F, Clarke J, Colas RA, Gomez EA, Keogh A, Boylan M, McEvoy N, McElvaney OJ, McElvaney O, Alalqam R, McElvaney NG, Curley GF and Dalli J (2021). Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients. Public Library of Science (Plos)  Plos One  vol. 16, (8) 10.1371/journal.pone.0256226
Piattini F, Matsushita M, Muri J, Bretscher P, Feng X, Freigang S, Dalli J, Schneider C and Kopf M (2021). Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis. Wiley  European Journal of Immunology  vol. 51, (10) 2417-2429. 10.1002/eji.202049114
Koenis DS, Beegun I, Jouvene CC, Aguirre GA, Souza PR, Gonzalez-Nunez M, Ly L, Pistorius K, Kocher HM, Ricketts W, Thomas G, Perretti M, Alusi G, Pfeffer P and Dalli J (2021). Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in COVID-19. Circulation Research  E54-E71. 10.1161/CIRCRESAHA.121.319142
Marques RM, Gonzalez-Nunez M, Walker ME, Gomez EA, Colas RA, Montero-Melendez T, Perretti M and Dalli J (2021). Loss of 15-lipoxygenase disrupts Treg differentiation altering their pro-resolving functions. Springer Nature  Cell Death & Differentiation  vol. 28, (11) 3140-3160. 10.1038/s41418-021-00807-x
Jagusch H, Werner M, Koenis D, Dalli J, Werz O and Pohnert G (2021). 14,17,18-Trihydroxy-Eicosatetraenoic Acid: A Novel Pro-Resolving Lipid Mediator from Marine Microalgae. American Chemical Society (Acs)  Acs Pharmacology & Translational Science  vol. 4, (3) 1188-1194. 10.1021/acsptsci.1c00057
Rossaint J, Thomas K, Mersmann S, Skupski J, Margraf A, Tekath T, Jouvene CC, Dalli J, Hidalgo A, Meuth SG, Soehnlein O and Zarbock A (2021). Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education. Rockefeller University Press  Journal of Experimental Medicine  vol. 218, (7) 10.1084/jem.20201353
Félix‐Soriano E, Sáinz N, Gil‐Iturbe E, Collantes M, Fernández‐Galilea M, Castilla‐Madrigal R, Ly L, Dalli J and Moreno‐Aliaga MJ (2021). Changes in brown adipose tissue lipid mediator signatures with aging, obesity, and DHA supplementation in female mice. Wiley  The Faseb Journal  vol. 35, (6) 10.1096/fj.202002531r
Sokal DM, McSloy A, Donegà M, Kirk J, Colas RA, Dolezalova N, Gomez EA, Gupta I, Fjordbakk CT, Ouchouche S, Matteucci PB, Schlegel K, Bashirullah R, Werling D, Harman K, Rowles A, Yazicioglu RF, Dalli J, Chew DJ and Perkins JD (2021). Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs. Frontiers  Frontiers in Immunology  vol. 12, 10.3389/fimmu.2021.649786
Sogorb-Esteve A, Colas RA, Dalli J and Rohrer JD (2021). Differential Lipid Mediator Involvement in the Different Forms of Genetic Frontotemporal Dementia: Novel Insights into Neuroinflammation. Ios Press  Journal of Alzheimer\'s Disease  vol. 84, (1) 283-289. 10.3233/jad-210559

2020

Sobrino A, Walker ME, Colas RA and Dalli J (2020). Protective activities of distinct omega-3 enriched oils are linked to their ability to upregulate specialized pro-resolving mediators. Public Library of Science (Plos)  Plos One  vol. 15, (12) 10.1371/journal.pone.0242543
Wood EG, Macdougall CE, Blythe H, Clément M, Colas RA, Dalli J, Marelli-Berg F and Longhi MP (2020). HIF1α activation in dendritic cells under sterile conditions promotes an anti-inflammatory phenotype through accumulation of intracellular lipids. Springer Nature  Scientific Reports  vol. 10, (1) 10.1038/s41598-020-77793-6
Gomez EA, Colas RA, Souza PR, Hands R, Lewis MJ, Bessant C, Pitzalis C and Dalli J (2020). Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis. Springer Nature  Nature Communications  vol. 11, (1) 10.1038/s41467-020-19176-z
Souza PR, Walker ME, Goulding NJ, Dalli J, Perretti M and Norling LV (2020). The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections. Frontiers Media  Frontiers in Immunology  vol. 11, 573019-573019. 10.3389/fimmu.2020.573019
Brancaleone V, Dalli J, di Villa Bianca RD and Pace S (2020). Editorial: Role of Blood Cells in Inflammatory and Vascular Disorders. Frontiers  Frontiers in Pharmacology  vol. 11, 10.3389/fphar.2020.585705
Chen J, Purvis GSD, Collotta D, Zoubi SA, Sugimoto MA, Cacace A, Martin L, Colas RA, Collino M, Dalli J and Thiemermann C (2020). RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance. Frontiers Media  Frontiers in Immunology  vol. 11, 2080-2080. 10.3389/fimmu.2020.02080
Schaller MS, Chen M, Colas RA, Sorrentino TA, Lazar AA, Grenon SM, Dalli J and Conte MS (2020). Treatment With a Marine Oil Supplement Alters Lipid Mediators and Leukocyte Phenotype in Healthy Patients and Those With Peripheral Artery Disease. Wolters Kluwer  Journal of The American Heart Association  vol. 9, (15) 10.1161/jaha.120.016113
Allen BL, Montague-Cardoso K, Simeoli R, Colas RA, Oggero S, Vilar B, McNaughton PA, Dalli J, Perretti M, Sher E and Malcangio M (2020). Imbalance of proresolving lipid mediators in persistent allodynia dissociated from signs of clinical arthritis. Lippincott, Williams & Wilkins  Pain  10.1097/j.pain.0000000000001908
Ruhanen H, Haridas PAN, Minicocci I, Taskinen JH, Palmas F, di Costanzo A, D'Erasmo L, Metso J, Partanen J, Dalli J, Zhou Y, Arca M, Jauhiainen M, Käkelä R and Olkkonen VM (2020). ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins. Elsevier  Biochimica Et Biophysica Acta (Bba) - Molecular and Cell Biology of Lipids  vol. 1865, (7) 10.1016/j.bbalip.2020.158679
Määttänen P, Lurz E, Botts SR, Wu RY, Robinson SC, Yeung CW, Colas R, Li B, Johnson‐Henry KC, Surette ME, Dalli J and Sherman PM (2020). Plant‐ and Fish‐Derived n‐3 PUFAs Suppress Citrobacter Rodentium–Induced Colonic Inflammation. Wiley  Molecular Nutrition & Food Research  vol. 64, (6) 10.1002/mnfr.201900873
Pangopoulos MK, Nolsøe JMN, Antonsen SG, Colas RA, Dalli J, Aursnes M, Stenstrøm Y and Hansen TV (2020). Enzymatic studies with 3-oxa n-3 DPA. Elsevier  Bioorganic Chemistry  vol. 96, 10.1016/j.bioorg.2020.103653
Wilcz‐Villega E, Carter E, Ironside A, Xu R, Mataloni I, Holdsworth J, Jones W, Béjar RM, Uhlik L, Bentham RB, Godinho SA, Dalli J, Grose R, Szabadkai G, Jones L, Hodivala‐Dilke K and Bianchi K (2020). Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway. Springer Nature  Embo Molecular Medicine  vol. 12, (2) 10.15252/emmm.201910491
Fussbroich D, Colas RA, Eickmeier O, Trischler J, Jerkic SP, Zimmermann K, Göpel A, Schwenger T, Schaible A, Henrich D, Baer P, Zielen S, Dalli J, Beermann C and Schubert R (2020). A combination of LCPUFA ameliorates airway inflammation in asthmatic mice by promoting pro-resolving effects and reducing adverse effects of EPA. Elsevier  Mucosal Immunology  vol. 13, (3) 481-492. 10.1038/s41385-019-0245-2

2019

Souza PR, Marques RM, Gomez EA, Colas RA, De Matteis R, Zak A, Patel M, Collier DJ and Dalli J (2019). Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses: A Randomized Double-Blind Placebo-Controlled Study. Circ Res  10.1161/CIRCRESAHA.119.315506
Flak MB, Koenis DS, Sobrino A, Smith J, Pistorius K, Palmas F and Dalli J (2019). GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections. American Society For Clinical Investigation  Journal of Clinical Investigation  vol. 130, (1) 359-373. 10.1172/jci131609
Shivakoti R, Dalli J, Kadam D, Gaikwad S, Barthwal M, Colas RA, Mazzacuva F, Lokhande R, Dharmshale S, Bharadwaj R, Kagal A, Pradhan N, Deshmukh S, Atre S, Sahasrabudhe T, Kakrani A, Kulkarni V, Raskar S, Suryavanshi N, Chon S, Gupte A, Gupta A, Gupte N, Arriaga MB, Fukutani KF, Andrade BB, Golub JE and Mave V (2019). Lipid mediators of inflammation and Resolution in individuals with tuberculosis and tuberculosis-Diabetes. Elsevier  Prostaglandins and Other Lipid Mediators  vol. 147, 10.1016/j.prostaglandins.2019.106398
Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN, Kalesse M and Hansen TV (2019). Addendum: Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n−3 DPA. Wiley  Chemistry - a European Journal  vol. 25, (66) 15212-15212. 10.1002/chem.201901350
Colas RA, Nhat LTH, Thuong NTT, Gómez EA, Ly L, Thanh HH, Mai NTH, Phu NH, Thwaites GE and Dalli J (2019). Proresolving mediator profiles in cerebrospinal fluid are linked with disease severity and outcome in adults with tuberculous meningitis. Faseb Journal : Official Publication of The Federation of American Societies For Experimental Biology  vol. 33, (11) 13028-13039. 10.1096/fj.201901590R
Thau-Zuchman O, Ingram R, Harvey GG, Cooke T, Palmas F, Pallier PN, Brook J, Priestley JV, Dalli J, Tremoleda JL and Michael-Titus AT (2019). A Single Injection of Docosahexaenoic Acid Induces a Pro-Resolving Lipid Mediator Profile in the Injured Tissue and a Long-Lasting Reduction in Neurological Deficit after Traumatic Brain Injury in Mice. Mary Ann Liebert  Journal of Neurotrauma  vol. 37, (1) 66-79. 10.1089/neu.2019.6420
Nesman JI, Primdahl KG, Tungen JE, Palmas F, Dalli J and Hansen TV (2019). Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA †. Mdpi  Molecules  vol. 24, (18) 10.3390/molecules24183228
Becares N, Härmälä S, China L, Colas RA, Maini AA, Bennet K, Skene SS, Shabir Z, Dalli J and O’Brien A (2019). Immune Regulatory Mediators in Plasma from Patients With Acute Decompensation Are Associated With 3-Month Mortality. Elsevier  Clinical Gastroenterology and Hepatology  vol. 18, (5) 1207-1215.e6. 10.1016/j.cgh.2019.08.036
Dakin SG, Colas RA, Wheway K, Watkins B, Appleton L, Rees J, Gwilym S, Little C, Dalli J and Carr AJ (2019). Proresolving Mediators LXB4 and RvE1 Regulate Inflammation in Stromal Cells from Patients with Shoulder Tendon Tears. Elsevier  American Journal of Pathology  vol. 189, (11) 2258-2268. 10.1016/j.ajpath.2019.07.011
Fosshaug LE, Colas RA, Anstensrud AK, Gregersen I, Nymo S, Sagen EL, Michelsen A, Vinge LE, Øie E, Gullestad L, Halvorsen B, Hansen TV, Aukrust P, Dalli J and Yndestad A (2019). Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction. Elsevier  Ebiomedicine  vol. 46, 264-273. 10.1016/j.ebiom.2019.07.024
Flak MB, Colas RA, Muñoz-Atienza E, Curtis MA, Dalli J and Pitzalis C (2019). Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis. American Society For Clinical Investigation  Jci Insight  vol. 4, (13) 10.1172/jci.insight.125191
Dakin SG, Colas RA, Newton J, Gwilym S, Jones N, Reid HAB, Wood S, Appleton L, Wheway K, Watkins B, Dalli J and Carr AJ (2019). 15-Epi-LXA4 and MaR1 counter inflammation in stromal cells from patients with Achilles tendinopathy and rupture. Faseb Journal : Official Publication of The Federation of American Societies For Experimental Biology  vol. 33, (7) 8043-8054. 10.1096/fj.201900196R
Dakin SG, Colas RA, Dean BJF, Wheway K, Watkins B, Dalli J and Carr AJ (2019). Tendon cells isolated from patients with persistent shoulder tendinopathy show dysregulated resolution responses. Hindawi  Translational Sports Medicine  vol. 2, (4) 173-176. 10.1002/tsm2.86
Holopainen M, Colas RA, Valkonen S, Tigistu-Sahle F, Hyvärinen K, Mazzacuva F, Lehenkari P, Käkelä R, Dalli J, Kerkelä E and Laitinen S (2019). Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells. Elsevier  Biochimica Et Biophysica Acta (Bba) - Molecular and Cell Biology of Lipids  vol. 1864, (10) 1350-1362. 10.1016/j.bbalip.2019.06.010
Sordi R, Chiazza F, Collotta D, Migliaretti G, Colas RA, Vulliamy P, Brohi K, Dalli J, Collino M and Thiemermann C (2019). Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock. Ann Surg  10.1097/SLA.0000000000003407
López-Vicario C, Titos E, Walker ME, Alcaraz-Quiles J, Casulleras M, Durán-Güell M, Flores-Costa R, Pérez-Romero N, Forné M, Dalli J and Clària J (2019). Leukocytes from obese individuals exhibit an impaired SPM signature. Faseb Journal : Official Publication of The Federation of American Societies For Experimental Biology  vol. 33, (6) 7072-7083. 10.1096/fj.201802587R
Valkonen S, Holopainen M, Colas RA, Impola U, Dalli J, Käkelä R, Siljander PR-M and Laitinen S (2019). Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules. Elsevier  Biochimica Et Biophysica Acta (Bba) - Molecular and Cell Biology of Lipids  vol. 1864, (8) 1168-1182. 10.1016/j.bbalip.2019.03.011
Sønderskov J, Tungen JE, Palmas F, Dalli J, Serhan CN, Stenstrøm Y and Vidar Hansen T (2019). Stereoselective synthesis of MaR2n-3 DPA. Tetrahedron Letters  10.1016/j.tetlet.2019.151510
Dalli J, Pistorius K and Walker ME (2019). Novel n-3 Docosapentaneoic Acid-Derived Pro-resolving Mediators Are Vasculoprotective and Mediate the Actions of Statins in Controlling Inflammation. Springer Verlag  Advances in Experimental Medicine and Biology  vol. 1161, 65-75. 10.1007/978-3-030-21735-8_7

2018

Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN, Kalesse M and Hansen TV (2018). Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA. Chemistry  vol. 25, (6) 1476-1480. 10.1002/chem.201806029
Serhan CN, Chiang N and Dalli J (2018). New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration. Mol Aspects Med  vol. 64, 1-17. 10.1016/j.mam.2017.08.002
Laguna-Fernandez A, Checa A, Carracedo M, Artiach G, Petri MH, Baumgartner R, Forteza MJ, Jiang X, Andonova T, Walker ME, Dalli J, Arnardottir H, Gisterå A, Thul S, Wheelock CE, Paulsson-Berne G, Ketelhuth DFJ, Hansson GK and Bäck M (2018). ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages. Circulation  vol. 138, (16) 1693-1705. 10.1161/CIRCULATIONAHA.117.032801
Frigerio F, Pasqualini G, Craparotta I, Marchini S, van Vliet EA, Foerch P, Vandenplas C, Leclercq K, Aronica E, Porcu L, Pistorius K, Colas RA, Hansen TV, Perretti M, Kaminski RM, Dalli J and Vezzani A (2018). n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis. Brain  vol. 141, (11) 3130-3143. 10.1093/brain/awy247
Chiang N, Riley IR, Dalli J, Rodriguez AR, Spur BW and Serhan CN (2018). New maresin conjugates in tissue regeneration pathway counters leukotriene D4–stimulated vascular responses. Faseb  The Faseb Journal  vol. 32, (7) 4043-4052. 10.1096/fj.201701493r
Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J, Thiemermann C and Ahluwalia A (2018). Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis. Faseb J  fj201701303-fj201701303. 10.1096/fj.201701303R
Pistorius K, Souza PR, De Matteis R, Austin-Williams S, Primdahl KG, Vik A, Mazzacuva F, Colas RA, Marques RM, Hansen TV and Dalli J (2018). PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function. Cell Chem Biol  vol. 25, (6) 749-760.e9. 10.1016/j.chembiol.2018.04.017
Dalli J and Serhan CN (2018). Identification and structure elucidation of the pro‐resolving mediators provides novel leads for resolution pharmacology. Wiley  British Journal of Pharmacology  vol. 176, (8) 1024-1037. 10.1111/bph.14336
Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F, Jelicks LA, dos Santos FM, Nagajyothi J, Zingman MA, Reyes J, Weiss LM, Serhan CN and Tanowitz HB (2018). Trypanosoma cruzi produces the specialized proresolving mediators resolvin D1, resolvin D5, and resolvin E2. Infection and Immunity  vol. 86, (4) 10.1128/IAI.00688-17
Motwani MP, Colas RA, George MJ, Flint JD, Dalli J, Richard-Loendt A, De Maeyer RPH, Serhan CN and Gilroy DW (2018). Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli–driven acute inflammation. American Society For Clinical Investigation  Jci Insight  vol. 3, (6) 10.1172/jci.insight.94463
Mai NTH, Dobbs N, Phu NH, Colas RA, Thao LTP, Thuong NTT, Nghia HDT, Hanh NHH, Hang NT, Heemskerk AD, Day JN, Ly L, Thu DDA, Merson L, Kestelyn E, Wolbers M, Geskus R, Summers D, Chau NVV, Dalli J and Thwaites GE (2018). A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults. Elife  Elife  vol. 7, 10.7554/elife.33478
Colas RA, Souza PR, Walker ME, Burton M, Zasłona Z, Curtis AM, Marques RM and Dalli J (2018). Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease. Wolters Kluwer  Circulation Research  vol. 122, (6) 855-863. 10.1161/circresaha.117.312472
Dalli J, Colas RA, Walker ME and Serhan CN (2018). Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis. Methods Mol Biol  vol. 1730, 59-72. 10.1007/978-1-4939-7592-1_4

2017

Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR, Schmidt B, Dalli J, Greene ER, Gus-Brautbar Y, Piwowarski J, Mammoto T, Zurakowski D, Perretti M, Sukhatme VP, Kaipainen A, Kieran MW, Huang S and Panigrahy D (2017). Resolvins suppress tumor growth and enhance cancer therapy. Rockefeller University Press  Journal of Experimental Medicine  vol. 215, (1) 115-140. 10.1084/jem.20170681
Dalli J and Serhan CN (2017). Immunoresolvents signaling molecules at intersection between the brain and immune system. Elsevier  Current Opinion in Immunology  vol. 50, 48-54. 10.1016/j.coi.2017.10.007
Dalli J and Serhan CN (2017). Pro-Resolving Mediators in Regulating and Conferring Macrophage Function. Frontiers Media  Front Immunol  vol. 8, 1400-1400. 10.3389/fimmu.2017.01400
Motwani MP, Newson J, Kwong S, Richard-Loendt A, Colas R, Dalli J and Gilroy DW (2017). Prolonged immune alteration following resolution of acute inflammation in humans. Public Library of Science  Plos One  vol. 12, (10) e0186964-e0186964. 10.1371/journal.pone.0186964
Primdahl KG, Tungen JE, De Souza PRS, Colas RA, Dalli J, Hansen TV and Vik A (2017). Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA. Org Biomol Chem  vol. 15, (40) 8606-8613. 10.1039/c7ob02113e
Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon J-S, Shinohara M, Hisata S, Howrylak JA, Suh G-Y, Ryter SW, Serhan CN and Choi AMK (2017). NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B4Synthesis. Am J Respir Crit Care Med  vol. 196, (6) 713-726. 10.1164/rccm.201604-0892OC
Dakin SG, Ly L, Colas RA, Oppermann U, Wheway K, Watkins B, Dalli J and Carr AJ (2017). Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy. Macmillan Publishing Group  Sci Rep  vol. 7, (1) 11009-11009. 10.1038/s41598-017-11188-y
China L, Maini A, Skene SS, Shabir Z, Sylvestre Y, Colas RA, Ly L, Salles NB, Belloti V, Dalli J, Gilroy DW and O’Brien A (2017). Albumin Counteracts Immune-Suppressive Effects of Lipid Mediators in Patients With Advanced Liver Disease. Elsevier  Clinical Gastroenterology and Hepatology  vol. 16, (5) 738-747.e7. 10.1016/j.cgh.2017.08.027
Walker ME, Souza PR, Colas RA and Dalli J (2017). 13‐Series resolvins mediate the leukocyte‐platelet actions of atorvastatin and pravastatin in inflammatory arthritis. Wiley  The Faseb Journal  vol. 31, (8) 3636-3648. 10.1096/fj.201700268
Reátegui E, Jalali F, Khankhel AH, Wong E, Cho H, Lee J, Serhan CN, Dalli J, Elliott H and Irimia D (2017). Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarming. Nature Biomedical Engineering  vol. 1, (7) 0094-0094. 10.1038/s41551-017-0094
Hansen TV, Dalli J and Serhan CN (2017). The Novel Lipid Mediator PD1n-3DPA: An Overview of the Structural Elucidation, Synthesis, Biosynthesis and Bioactions. Elsevier  Prostaglandins and Other Lipid Mediators  10.1016/j.prostaglandins.2017.06.003
Perretti M, Di Filippo C, D'Amico M and Dalli J (2017). Characterizing the anti-inflammatory and tissue protective actions of a novel Annexin A1 peptide. Public Library of Science  Plos One  vol. 12, (4) e0175786-e0175786. 10.1371/journal.pone.0175786
Dalli J (2017). Does promoting resolution instead of inhibiting inflammation represent the new paradigm in treating infections? Elsevier  Molecular Aspects of Medicine  vol. 58, 12-20. 10.1016/j.mam.2017.03.007
Vik A, Dalli J and Hansen TV (2017). Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid. Elsevier  Bioorganic & Medicinal Chemistry Letters  vol. 27, (11) 2259-2266. 10.1016/j.bmcl.2017.03.079
PERRETTI M, Dalli J, Colas R, Federici Canova D and Gobbetti T (2017). Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection. National Academy of Sciences  Proceedings of The National Academy of Sciences of The United States of America  vol. 114, (15) 3963-3968. 10.1073/pnas.1617290114
Norling LV, Ly L and Dalli J (2017). Resolving inflammation by using nutrition therapy: roles for specialized proresolving mediators. Curr Opin Clin Nutr Metab Care  vol. 20, (2) 145-152. 10.1097/MCO.0000000000000353
Dalli J, Colas RA, Arnardottir H and Serhan CN (2017). Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution. Immunity  vol. 46, (1) 92-105. 10.1016/j.immuni.2016.12.009
Freire MO, Dalli J, Serhan CN and Van Dyke TE (2017). Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes. The American Association of Immunologists  The Journal of Immunology  vol. 198, (2) 718-728. 10.4049/jimmunol.1601543
Dalli J and Serhan C (2017). Macrophage Proresolving Mediators—the When and Where. Myeloid Cells in Health and Disease  American Society For Microbiology  10.1128/9781555819194.ch20
Perretti M, Cooper D, Dalli J and Norling LV (2017). Immune resolution mechanisms in inflammatory arthritis. Nat Rev Rheumatol  vol. 13, (2) 87-99. 10.1038/nrrheum.2016.193
China L, Maini A, Colas R, Ly L, Dalli J, Gilroy D, O’Brien A and Group ATM (2017). FRI-054 Plasma lipid mediator (LM) profiling identifies hyper- and hypo-activated groups of patients with ACLF and targeted 20% human albumin solution infusion recalibrates abnormalities. Elsevier  Journal of Hepatology  vol. 66, (1) 10.1016/s0168-8278(17)31131-5

2016

Colas RA, Dalli J, Chiang N, Vlasakov I, Sanger JM, Riley IR and Serhan CN (2016). Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation. J Immunol  vol. 197, (11) 4444-4452. 10.4049/jimmunol.1600837
AHLUWALIA A (2016). Accelerated resolution underlies sex differences in the inflammatory response in human. American Society For Clinical Investigation  Journal of Clinical Investigation  vol. 127, (1) 169-182. 10.1172/JCI89429.
Tsoyi K, Hall SRR, Dalli J, Colas RA, Ghanta S, Ith B, Coronata A, Fredenburgh LE, Baron RM, Choi AMK, Serhan CN, Liu X and Perrella MA (2016). Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators*. Wolters Kluwer  Critical Care Medicine  vol. 44, (12) e1236-e1245. 10.1097/ccm.0000000000001999
Primdahl KG, Aursnes M, Walker ME, Colas RA, Serhan CN, Dalli J, Hansen TV and Vik A (2016). Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins. J Nat Prod  vol. 79, (10) 2693-2702. 10.1021/acs.jnatprod.6b00634
Titos E, Rius B, López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Lopategi A, Dalli J, Lozano JJ, Arroyo V, Delgado S, Serhan CN and Clària J (2016). Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue. The American Association of Immunologists  The Journal of Immunology  vol. 197, (8) 3360-3370. 10.4049/jimmunol.1502522
DALLI J (2016). Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages. National Academy of Sciences  Proceedings of The National Academy of Sciences of Usa  vol. 113, (43) 10.1073/pnas.1607003113
DALLI J and Colas RC (2016). Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes. Lippincott, Williams & Wilkins  Critical Care Medicine  10.1097/CCM.0000000000002014
DALLI JP (2016). Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses. American Association For The Advancement of Science  Science Translational Medicine  vol. 8, (353) 10.1126/scitranslmed.aaf7483
Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M and Serhan CN (2016). Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. American Association of Immunologists  Journal of Immunology  vol. 197, (6) 2362-2368. 10.4049/jimmunol.1502268
Dalli J, Chiang N and Serhan C (2016). AB0042 Identification of Sulfido-Conjugated Mediators That Promote Resolution of Infection and Organ Protection. Bmj  Annals of The Rheumatic Diseases  vol. 75, (Suppl 2) 10.1136/annrheumdis-2016-eular.6149
Colby JK, Abdulnour R-EE, Sham HP, Dalli J, Colas RA, Winkler JW, Hellmann J, Wong B, Cui Y, El-Chemaly S, Petasis NA, Spite M, Serhan CN and Levy BD (2016). Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. Elsevier  American Journal of Pathology  vol. 186, (7) 1801-1813. 10.1016/j.ajpath.2016.03.011
Dalli J and Serhan C (2016). Macrophage Proresolving Mediators-the When and Where. American Society For Microbiology  Microbiology Spectrum  vol. 4, (3) 10.1128/microbiolspec.mchd-0001-2014
Elajami TK, Colas RA, Dalli J, Chiang N, Serhan CN and Welty FK (2016). Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling. Wiley  The Faseb Journal  vol. 30, (8) 2792-2801. 10.1096/fj.201500155r
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN and Perretti M (2016). Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis. American Society For Clinical Investigation  Jci Insight  vol. 1, (5) 10.1172/jci.insight.85922
Dalli J (2016). LIPID MEDIATORS AND THE RESOLUTION OF CHRONIC INFLAMMATION: IMPLICATIONS FOR ARTHRITIS THERAPY. Osteoarthritis and Cartilage  vol. 24, S2-S2. 10.1016/j.joca.2016.01.021
Dalli J, Sanger JM, Rodriguez AR, Chiang N, Spur BW and Serhan CN (2016). Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3. Public Library of Science (Plos)  Plos One  vol. 11, (2) 10.1371/journal.pone.0149319
Ramon S, Dalli J, Sanger JM, Winkler JW, Aursnes M, Tungen JE, Hansen TV and Serhan CN (2016). The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation. Elsevier  American Journal of Pathology  vol. 186, (4) 962-973. 10.1016/j.ajpath.2015.12.012
Winkler JW, Orr SK, Dalli J, Cheng C-YC, Sanger JM, Chiang N, Petasis NA and Serhan CN (2016). Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance. Springer Nature  Scientific Reports  vol. 6, (1) 10.1038/srep18972
Hansen TV, Dalli J and Serhan CN (2016). Selective identification of specialized pro-resolving lipid mediators from their biosynthetic double di-oxygenation isomers. Royal Society of Chemistry (Rsc)  Rsc Advances  vol. 6, (34) 28820-28829. 10.1039/c6ra00414h
Fiala M, Terrando N and Dalli J (2016). Specialized Pro-Resolving Mediators from Omega-3 Fatty Acids Improve Amyloid-β Phagocytosis and Regulate Inflammation in Patients with Minor Cognitive Impairment. Ios Press  Journal of Alzheimer\'s Disease  vol. 49, (4) 1191-1191. 10.3233/jad-159008

2015

Wang C-W, Colas RA, Dalli J, Arnardottir HH, Nguyen D, Hasturk H, Chiang N, Van Dyke TE and Serhan CN (2015). Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes. American Society For Microbiology  Infection and Immunity  vol. 84, (3) 658-665. 10.1128/iai.01131-15
Abdulnour RE, Sham HP, Douda DN, Colas RA, Dalli J, Bai Y, Ai X, Serhan CN and Levy BD (2015). Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation. Elsevier  Mucosal Immunology  vol. 9, (5) 1278-1287. 10.1038/mi.2015.129
Cianci E, Recchiuti A, Trubiani O, Diomede F, Marchisio M, Miscia S, Colas RA, Dalli J, Serhan CN and Romano M (2015). Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins. Oxford University Press (Oup)  Stem Cells Translational Medicine  vol. 5, (1) 20-32. 10.5966/sctm.2015-0163
Aursnes M, Tungen JE, Colas RA, Vlasakov I, Dalli J, Serhan CN and Hansen TV (2015). Synthesis of the 16S,17S‑Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages. American Chemical Society (Acs)  Journal of Natural Products  vol. 78, (12) 2924-2931. 10.1021/acs.jnatprod.5b00574
Arnardottir H, Orr SK, Dalli J and Serhan CN (2015). Human milk proresolving mediators stimulate resolution of acute inflammation. Elsevier  Mucosal Immunology  vol. 9, (3) 757-766. 10.1038/mi.2015.99
Dalli J, Kraft BD, Colas RA, Shinohara M, Fredenburgh LE, Hess DR, Chiang N, Welty-Wolf K, Choi AM, Piantadosi CA and Serhan CN (2015). The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide. American Thoracic Society  American Journal of Respiratory Cell and Molecular Biology  vol. 53, (3) 314-325. 10.1165/rcmb.2014-0299oc
Croasdell A, Thatcher TH, Kottmann RM, Colas RA, Dalli J, Serhan CN, Sime PJ and Phipps RP (2015). Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages. American Physiological Society  American Journal of Physiology - Lung Cellular and Molecular Physiology  vol. 309, (8) l888-l901. 10.1152/ajplung.00125.2015
Dalli J, Chiang N and Serhan CN (2015). Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections. Springer Nature  Nature Medicine  vol. 21, (9) 1071-1075. 10.1038/nm.3911
Chiang N, Dalli J, Colas RA and Serhan CN (2015). Identification of resolvin D2 receptor mediating resolution of infections and organ protection. Rockefeller University Press  Journal of Experimental Medicine  vol. 212, (8) 1203-1217. 10.1084/jem.20150225
Ramirez JL, de Almeida Oliveira G, Calvo E, Dalli J, Colas RA, Serhan CN, Ribeiro JM and Barillas-Mury C (2015). A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae. Springer Nature  Nature Communications  vol. 6, (1) 10.1038/ncomms8403
Börgeson E, Johnson AMF, Lee YS, Till A, Syed GH, Ali-Shah ST, Guiry PJ, Dalli J, Colas RA, Serhan CN, Sharma K and Godson C (2015). Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease. Elsevier  Cell Metabolism  vol. 22, (1) 125-137. 10.1016/j.cmet.2015.05.003
Kain V, Ingle KA, Colas RA, Dalli J, Prabhu SD, Serhan CN, Joshi M and Halade GV (2015). Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function. Elsevier  Journal of Molecular and Cellular Cardiology  vol. 84, 24-35. 10.1016/j.yjmcc.2015.04.003
Serhan CN, Chiang N and Dalli J (2015). The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution. Elsevier  Seminars in Immunology  vol. 27, (3) 200-215. 10.1016/j.smim.2015.03.004
Dalli J, Chiang N and Serhan C (2015). Novel Peptide‐Conjugated Maresins Stimulate Tissue Regeneration and Clearance of Infections in Planaria and Inflammatory Exudates. Wiley  The Faseb Journal  vol. 29, (S1) 10.1096/fasebj.29.1_supplement.285.5
Sulciner M, Mudge D, Ramon S, Dalli J, Kieran M, Huang S, Serhan C and Panigrahy D (2015). Suppression of Cell Debris‐Stimulated Tumor Growth by Resolvin Mediated Clearance. Wiley  The Faseb Journal  vol. 29, (S1) 10.1096/fasebj.29.1_supplement.926.14
Winkler J, Orr S, Dalli J, Chiang N, Petasis N and Serhan C (2015). Resolvin D4 Potent Antiiinflammatory Proresolving Actions Confirmed via Total Synthesis. Wiley  The Faseb Journal  vol. 29, (S1) 10.1096/fasebj.29.1_supplement.285.10
Ramon S, Dalli J, Norris P, Colas R and Serhan C (2015). Elucidation of Resolvin and Protectin Sulfido‐Conjugated Mediators: New Pro‐Resolving and Tissue Regenerative Pathways. Wiley  The Faseb Journal  vol. 29, (S1) 10.1096/fasebj.29.1_supplement.lb423
Arnardottir H, Orr S, Dalli J and Serhan C (2015). Human Milk Stimulates Resolution of Acute Inflammation. Wiley  The Faseb Journal  vol. 29, (S1) 10.1096/fasebj.29.1_supplement.913.14
Orr SK, Colas RA, Dalli J, Chiang N and Serhan CN (2015). Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent. American Physiological Society  American Journal of Physiology - Lung Cellular and Molecular Physiology  vol. 308, (9) l904-l911. 10.1152/ajplung.00370.2014
Amoruso A, Fresu LG, Dalli J, Miglietta D, Bardelli C, Canova DF, Perretti M and Brunelleschi S (2015). Characterization of the anti-inflammatory properties of NCX 429, a dual-acting compound releasing nitric oxide and naproxen. Elsevier  Life Sciences  vol. 126, 28-36. 10.1016/j.lfs.2015.01.025
Dalli J, Ramon S, Norris PC, Colas RA and Serhan CN (2015). Novel proresolving and tissue‐regenerative resolvin and protectin sulfido‐conjugated pathways. Wiley  The Faseb Journal  vol. 29, (5) 2120-2136. 10.1096/fj.14-268441
Krishnamoorthy N, Burkett PR, Dalli J, Abdulnour R-EE, Colas R, Ramon S, Phipps RP, Petasis NA, Kuchroo VK, Serhan CN and Levy BD (2015). Cutting Edge: Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of Lung Inflammation. The American Association of Immunologists  The Journal of Immunology  vol. 194, (3) 863-867. 10.4049/jimmunol.1402534
Fiala M, Terrando N and Dalli J (2015). Specialized Pro-Resolving Mediators from Omega-3 Fatty Acids Improve Amyloid-β Phagocytosis and Regulate Inflammation in Patients with Minor Cognitive Impairment. Ios Press  Journal of Alzheimer\'s Disease  vol. 48, (2) 293-301. 10.3233/jad-150367

2014

Van Dyke TE, Hasturk H, Kantarci A, Freire MO, Nguyen D, Dalli J and Serhan CN (2014). Proresolving Nanomedicines Activate Bone Regeneration in Periodontitis. Sage Publications  Journal of Dental Research  vol. 94, (1) 148-156. 10.1177/0022034514557331
Abdulnour R-EE, Dalli J, Colby JK, Krishnamoorthy N, Timmons JY, Tan SH, Colas RA, Petasis NA, Serhan CN and Levy BD (2014). Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective. Proceedings of The National Academy of Sciences  Proceedings of The National Academy of Sciences of The United States of America  vol. 111, (46) 16526-16531. 10.1073/pnas.1407123111
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN and Hansen TV (2014). Total synthesis of the anti-inflammatory and pro-resolving lipid mediator MaR1n-3 DPA utilizing an sp(3) -sp(3) Negishi cross-coupling reaction. Chemistry  vol. 20, (45) 14575-14578. 10.1002/chem.201404721
Serhan CN, Chiang N, Dalli J and Levy BD (2014). Lipid Mediators in the Resolution of Inflammation. Cold Spring Harbor Laboratory  Cold Spring Harbor Perspectives in Biology  vol. 7, (2) 10.1101/cshperspect.a016311
Dalli J, Colas RA and Serhan CN (2014). Erratum: CORRIGENDUM: Novel n-3 Immunoresolvents: Structures and Actions. Springer Nature  Scientific Reports  vol. 4, (1) 10.1038/srep06726
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN and Hansen TV (2014). Cover Picture: Total Synthesis of the Anti‐inflammatory and Pro‐resolving Lipid Mediator MaR1n−3 DPA Utilizing an sp3–sp3 Negishi Cross‐Coupling Reaction (Chem. Eur. J. 45/2014). Wiley  Chemistry - a European Journal  vol. 20, (45) 14533-14533. 10.1002/chem.201490186
Dalli J, Chiang N and Serhan CN (2014). Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection. Proceedings of The National Academy of Sciences  Proceedings of The National Academy of Sciences of The United States of America  vol. 111, (44) e4753-e4761. 10.1073/pnas.1415006111
Frediani JK, Jones DP, Tukvadze N, Uppal K, Sanikidze E, Kipiani M, Tran VT, Hebbar G, Walker DI, Kempker RR, Kurani SS, Colas RA, Dalli J, Tangpricha V, Serhan CN, Blumberg HM and Ziegler TR (2014). Plasma Metabolomics in Human Pulmonary Tuberculosis Disease: A Pilot Study. Public Library of Science (Plos)  Plos One  vol. 9, (10) 10.1371/journal.pone.0108854
Arnardottir HH, Dalli J, Colas RA, Shinohara M and Serhan CN (2014). Aging Delays Resolution of Acute Inflammation in Mice: Reprogramming the Host Response with Novel Nano-Proresolving Medicines. The American Association of Immunologists  The Journal of Immunology  vol. 193, (8) 4235-4244. 10.4049/jimmunol.1401313
Tungen JE, Aursnes M, Vik A, Ramon S, Colas RA, Dalli J, Serhan CN and Hansen TV (2014). Synthesis and Anti-inflammatory and Pro-resolving Activities of 22-OH-PD1, a Monohydroxylated Metabolite of Protectin D1. American Chemical Society (Acs)  Journal of Natural Products  vol. 77, (10) 2241-2247. 10.1021/np500498j
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN and Hansen TV (2014). Total Synthesis of the Anti‐inflammatory and Pro‐resolving Lipid Mediator MaR1n−3 DPA Utilizing an sp3–sp3 Negishi Cross‐Coupling Reaction. Wiley  Chemistry - a European Journal  vol. 20, (45) 14575-14578. 10.1002/chem.201404721
Shinohara M, Kibi M, Riley IR, Chiang N, Dalli J, Kraft BD, Piantadosi CA, Choi AMK and Serhan CN (2014). Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1. American Physiological Society  American Journal of Physiology - Lung Cellular and Molecular Physiology  vol. 307, (10) l746-l757. 10.1152/ajplung.00166.2014
Serhan CN, Dalli J, Colas RA, Winkler JW and Chiang N (2014). Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome. Elsevier  Biochimica Et Biophysica Acta  vol. 1851, (4) 397-413. 10.1016/j.bbalip.2014.08.006
Deng B, Wang C-W, Arnardottir HH, Li Y, Cheng C-YC, Dalli J and Serhan CN (2014). Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages. Public Library of Science (Plos)  Plos One  vol. 9, (7) 10.1371/journal.pone.0102362
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B and Perretti M (2014). 15. Neutrophils in GCA. Oxford University Press (Oup)  Rheumatology  vol. 53, (suppl_2) i9-i9. 10.1093/rheumatology/keu200
McCauley LK, Dalli J, Koh AJ, Chiang N and Serhan CN (2014). Cutting Edge: Parathyroid Hormone Facilitates Macrophage Efferocytosis in Bone Marrow via Proresolving Mediators Resolvin D1 and Resolvin D2. The American Association of Immunologists  The Journal of Immunology  vol. 193, (1) 26-29. 10.4049/jimmunol.1301945
Aursnes M, Tungen JE, Vik A, Dalli J and Hansen TV (2014). ChemInform Abstract: Stereoselective Synthesis of Protectin D1: A Potent Antiinflammatory and Proresolving Lipid Mediator. Wiley  Cheminform  vol. 45, (26) no-no. 10.1002/chin.201426218
Mirakaj V, Dalli J, Granja T, Rosenberger P and Serhan CN (2014). Vagus nerve controls resolution and pro-resolving mediators of inflammation. Rockefeller University Press  Journal of Experimental Medicine  vol. 211, (6) 1037-1048. 10.1084/jem.20132103
Colas RA, Shinohara M, Dalli J, Chiang N and Serhan CN (2014). Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue. American Physiological Society  American Journal of Physiology - Cell Physiology  vol. 307, (1) c39-c54. 10.1152/ajpcell.00024.2014
Frediani J, Jones D, Tukvadze N, Sanikidze E, Kipiani M, Uppal K, Kurani S, Hebbar G, Colas R, Dalli J, Serhan C, Tangpricha V, Blumberg H and Ziegler T (2014). Plasma high‐resolution metabolomic profiling reveals upregulation of specific resolvins in patients with pulmonary tuberculosis (248.3). Wiley  The Faseb Journal  vol. 28, (S1) 10.1096/fasebj.28.1_supplement.248.3
Aursnes M, Tungen JE, Vik A, Colas R, Cheng C-YC, Dalli J, Serhan CN and Hansen TV (2014). Total Synthesis of the Lipid Mediator PD1n‑3 DPA: Configurational Assignments and Anti-inflammatory and Pro-resolving Actions. American Chemical Society (Acs)  Journal of Natural Products  vol. 77, (4) 910-916. 10.1021/np4009865
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B and Perretti M (2014). Investigational analysis reveals a potential role for neutrophils in giant-cell arteritis disease progression. Circ Res  vol. 114, (2) 242-248. 10.1161/CIRCRESAHA.114.301374
Dalli J, Norling LV, Montero-Melendez T, Federici Canova D, Lashin H, Pavlov AM, Sukhorukov GB, Hinds CJ and Perretti M (2014). Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis. Embo Mol Med  vol. 6, (1) 27-42. 10.1002/emmm.201303503
Serhan CN, Chiang N and Dalli J (2014). Macrophages and the Entrance of Resolution Phase Lipid Mediators. Macrophages: Biology and Role in The Pathology of Diseases  Springer Nature  10.1007/978-1-4939-1311-4_13
Aursnes M, Tungen JE, Vik A, Dalli J and Hansen TV (2014). Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator. Royal Society of Chemistry (Rsc)  Organic & Biomolecular Chemistry  vol. 12, (3) 432-437. 10.1039/c3ob41902a

2013

Li Y, Dalli J, Chiang N, Baron RM, Quintana C and Serhan CN (2013). Plasticity of Leukocytic Exudates in Resolving Acute Inflammation Is Regulated by MicroRNA and Proresolving Mediators. Elsevier  Immunity  vol. 39, (5) 885-898. 10.1016/j.immuni.2013.10.011
Divanovic S, Dalli J, Jorge-Nebert LF, Flick LM, Gálvez-Peralta M, Boespflug ND, Stankiewicz TE, Fitzgerald JM, Somarathna M, Karp CL, Serhan CN and Nebert DW (2013). Contributions of the Three CYP1 Monooxygenases to Pro-Inflammatory and Inflammation-Resolution Lipid Mediator Pathways. The American Association of Immunologists  The Journal of Immunology  vol. 191, (6) 3347-3357. 10.4049/jimmunol.1300699
Norling LV and Dalli J (2013). Microparticles are novel effectors of immunity. Curr Opin Pharmacol  vol. 13, (4) 570-575. 10.1016/j.coph.2013.05.008
Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M and Perretti M (2013). Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Mol Cell Proteomics  vol. 12, (8) 2205-2219. 10.1074/mcp.M113.028589
Dalli J, Consalvo AP, Ray V, Di Filippo C, D'Amico M, Mehta N and Perretti M (2013). Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A4 receptor. J Immunol  vol. 190, (12) 6478-6487. 10.4049/jimmunol.1203000
Chiang N, Shinohara M, Dalli J, Mirakaj V, Kibi M, Choi AMK and Serhan CN (2013). Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Unique Proresolving Mediator–Heme Oxygenase-1 Circuits. The American Association of Immunologists  The Journal of Immunology  vol. 190, (12) 6378-6388. 10.4049/jimmunol.1202969
Montero-Melendez T, Dalli J and Perretti M (2013). Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors. Cell Death Differ  vol. 20, (4) 567-575. 10.1038/cdd.2012.154
Dalli J and Serhan C (2013). Pro‐Resolving Mediator Production by Human Phagocytes and their Transcellular Biosynthesis with Microparticles in Inflammation‐Resolution. Wiley  The Faseb Journal  vol. 27, (S1) 1168.4-1168.4. 10.1096/fasebj.27.1_supplement.1168.4
Li Y, Fredman G, Dalli J, Chiang N and Serhan CN (2013). Temporal Regulation of Pro‐Resolving Mediators and MicroRNA in Self‐Limited versus Delayed Resolution of Acute Inflammation. Wiley  The Faseb Journal  vol. 27, (S1) 816.4-816.4. 10.1096/fasebj.27.1_supplement.816.4
Gao F, Dalli J, Claria J and Serhan CN (2013). E. coli peritonitis initiates D‐series Resolvin‐metabolome. Wiley  The Faseb Journal  vol. 27, (S1) 822.9-822.9. 10.1096/fasebj.27.1_supplement.822.9
Shinohara M, Chiang N, Dalli J, Mirakaj V, Choi AMK and Serhan CN (2013). Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Novel Pro‐resolving Mediators and Heme Oxygenase‐1. Wiley  The Faseb Journal  vol. 27, (S1) 649.2-649.2. 10.1096/fasebj.27.1_supplement.649.2
Dalli J, Karamnov S, Zhu M, Petasis N and Serhan CN (2013). Maresin 1 a Novel Macrophage n‐3 Derived Mediator is a Potent Tissue Regenerative Immunoresolvent. Wiley  The Faseb Journal  vol. 27, (S1) 379.11-379.11. 10.1096/fasebj.27.1_supplement.379.11
Dalli J, Zhu M, Vlasenko NA, Deng B, Haeggström JZ, Petasis NA and Serhan CN (2013). The novel 13S,14S ‐epoxy‐maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype. Wiley  The Faseb Journal  vol. 27, (7) 2573-2583. 10.1096/fj.13-227728
Dalli J, Winkler JW, Colas RA, Arnardottir H, Cheng C-YC, Chiang N, Petasis NA and Serhan CN (2013). Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents. Elsevier  Cell Chemical Biology  vol. 20, (2) 188-201. 10.1016/j.chembiol.2012.11.010
Sampaio ALF, Dalli J, Brancaleone V, D'Acquisto F, Perretti M and Wheatley C (2013). Biphasic modulation of NOS expression, protein and nitrite products by hydroxocobalamin underlies its protective effect in endotoxemic shock: downstream regulation of COX-2, IL-1β, TNF-α, IL-6, and HMGB1 expression. Mediators Inflamm  vol. 2013, 10.1155/2013/741804
Dalli J, Colas RA and Serhan CN (2013). Novel n-3 Immunoresolvents: Structures and Actions. Springer Nature  Scientific Reports  vol. 3, (1) 10.1038/srep01940

2012

Jones CN, Dalli J, Dimisko L, Wong E, Serhan CN and Irimia D (2012). Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions. Proceedings of The National Academy of Sciences  Proceedings of The National Academy of Sciences of The United States of America  vol. 109, (50) 20560-20565. 10.1073/pnas.1210269109
Clària J, Dalli J, Yacoubian S, Gao F and Serhan CN (2012). Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat. The American Association of Immunologists  The Journal of Immunology  vol. 189, (5) 2597-2605. 10.4049/jimmunol.1201272
Dalli J and Serhan CN (2012). Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators. American Society of Hematology  Blood  vol. 120, (15) e60-e72. 10.1182/blood-2012-04-423525
Norling LV, Dalli J, Flower RJ, Serhan CN and Perretti M (2012). Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arterioscler Thromb Vasc Biol  vol. 32, (8) 1970-1978. 10.1161/ATVBAHA.112.249508
Giera M, Ioan-Facsinay A, Toes R, Gao F, Dalli J, Deelder AM, Serhan CN and Mayboroda OA (2012). Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC–MS/MS. Elsevier  Biochimica Et Biophysica Acta  vol. 1821, (11) 1415-1424. 10.1016/j.bbalip.2012.07.011
Chen X, Barozzi I, Termanini A, Prosperini E, Recchiuti A, Dalli J, Mietton F, Matteoli G, Hiebert S and Natoli G (2012). Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages. Proceedings of The National Academy of Sciences  Proceedings of The National Academy of Sciences of The United States of America  vol. 109, (42) e2865-e2874. 10.1073/pnas.1121131109
Serhan CN, Dalli J, Karamnov S, Choi A, Park C, Xu Z, Ji R, Zhu M and Petasis NA (2012). Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain. Wiley  The Faseb Journal  vol. 26, (4) 1755-1765. 10.1096/fj.11-201442
Dalli J, Jones CP, Cavalcanti DM, Farsky SH, Perretti M and Rankin SM (2012). Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow. Faseb J  vol. 26, (1) 387-396. 10.1096/fj.11-182089
Dalli J, Montero-Melendez T, McArthur S and Perretti M (2012). Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Front Pharmacol  vol. 3, 10.3389/fphar.2012.00028
Cardini S, Dalli J, Fineschi S, Perretti M, Lungarella G and Lucattelli M (2012). Genetic Ablation of the Fpr1 Gene Confers Protection from Smoking-Induced Lung Emphysema in Mice. American Journal of Respiratory Cell and Molecular Biology  vol. 47, (3) 332-339. 10.1165/rcmb.2012-0036OC
Fredman G, Li Y, Dalli J, Chiang N and Serhan CN (2012). Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA. Springer Nature  Scientific Reports  vol. 2, (1) 10.1038/srep00639

2011

Brancaleone V, Dalli J, Bena S, Flower RJ, Cirino G and Perretti M (2011). Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature. J Immunol  vol. 186, (8) 4905-4914. 10.4049/jimmunol.1003145
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC, Perretti M and Flower RJ (2011). Corrections: Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation. The American Association of Immunologists  The Journal of Immunology  vol. 186, (4) 2684-2685. 10.4049/jimmunol.1090139
Brown SM, Dalli J, Perretti M, Bush A, Davies JC and Lloyd CM (2011). THE INFLAMMATORY RESOLUTION PROTEIN ANNEXIN A1 AND THE PAEDIATRIC CF AIRWAY. Pediatric Pulmonology  265-266.

2010

Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M and D'Acquisto F (2010). Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature. Blood  vol. 116, (20) 4288-4296. 10.1182/blood-2010-02-270520
Maderna P, Cottell DC, Toivonen T, Dufton N, Dalli J, Perretti M and Godson C (2010). FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis. Faseb J  vol. 24, (11) 4240-4249. 10.1096/fj.10-159913
Renshaw D, Montero-Melendez T, Dalli J, Kamal A, Brancaleone V, D'Acquisto F, Cirino G and Perretti M (2010). Downstream gene activation of the receptor ALX by the agonist annexin A1. Plos One  vol. 5, (9) 10.1371/journal.pone.0012771
Dalli J, Rosignoli G, Hayhoe RPG, Edelman A and Perretti M (2010). CFTR inhibition provokes an inflammatory response associated with an imbalance of the annexin A1 pathway. Am J Pathol  vol. 177, (1) 176-186. 10.2353/ajpath.2010.091149
Dalli J, Rosignoli G, Hayhoe RPG, Edelman A and Perretti M (2010). CFTR Inhibition Provokes an Inflammatory Response Associated with an Imbalance of the Annexin A1 Pathway. Am J Pathol  vol. 177, (1) 176-186. 10.2353/ajpath.2010.091149
Norling LV, Dalli J, Flower RJ, Serhan CN and Perretti M (2010). Resolvin D1 limits PMN recruitment to inflammatory loci: receptor dependent bioactions. Faseb Journal  vol. 24,
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC, Perretti M and Flower RJ (2010). Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation. J Immunol  vol. 184, (5) 2611-2619. 10.4049/jimmunol.0903526

2009

Perretti M and Dalli J (2009). Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics. Br J Pharmacol  vol. 158, (4) 936-946. 10.1111/j.1476-5381.2009.00483.x
Gastardelo TS, Damazo AS, Dalli J, Flower RJ, Perretti M and Oliani SM (2009). Functional and Ultrastructural Analysis of Annexin A1 and Its Receptor in Extravasating Neutrophils during Acute Inflammation. Am J Pathol  vol. 174, (1) 177-183. 10.2353/ajpath.2009.080342

2008

Dalli J, Norling LV, Renshaw D, Cooper D, Leung KY and Perretti M (2008). Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles. Blood  vol. 112, (6) 2512-2519. 10.1182/blood-2008-02-140533

2007

Gavins FNE, Dalli J, Flower RJ, Granger DN and Perretti M (2007). Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation. Faseb J  vol. 21, (8) 1751-1758. 10.1096/fj.06-7842com

Grants

Grants of specific relevance to Predictive in vitro Models
Cell DIVE Imager for automated, single cell, multiplexed immunofluorescence microscopy
Bishop CL, Bourke CD, Chan LF, Dalli J, Graham TA, Licenikova Horejsi Z, Martin-Duran JM, Nourshargh S, Prendergast A and Riches J
£340,339 Wellcome Trust (20-11-2021 - 19-11-2026)
Summary
Identifying novel receptor targets - ECIS equipment
Dalli JP
£45,000 Barts Charity (06-08-2018 - 08-10-2024)
SPMAC: The role of pro-resolving lipid mediators and gut-resident macrophages in regulating early-in-life immune imprinting and adulthood [...]
Albuquerque De Souza E and Dalli J
£190,380 UK Research and Innovation (31-08-2022 - 30-08-2024)
Summary

Vagal Regulation of RvDn-3 DPA in Cardiovascular Protection during IA
Dalli JP
£201,599 Barts Charity (03-09-2018 - 31-08-2021)
Resolution Pharmacology and Physiology of MCTR in Arthritis
Dalli J
EUR1,964,303 European Research Council (01-03-2016 - 31-08-2021)
Summary
Starting Grant
Dalli JP
European Research Council (01-04-2016 - 01-03-2021)
Using Signature Lipid Mediator Profiles for Innovative Approaches to Patient Stratification and Precision Medicine
Dalli JP
Barts Charity (01-01-2017 - 31-12-2020)
Development and Validation of Methods to Measure Resolvin E1 Target Engagement in Colon Tissue
Sciavolino F, Hanley M, Nusrat A and Dalli J
USD270,000 Crohn's and Colitis Foundation (04-11-2019 - 03-11-2020)
Statin triggered-novel resolvins as innovative resolution-based therapeutics in arthritis
Dalli J
£972,164 Wellcome Trust (07-09-2015 - 20-10-2020)
Summary