Prof Jesmond Dalli

Jesmond Dalli

Professor in Molecular Pharmacology

Barts and The London School of Medicine and Dentistry
jdallilab.com/
ORCID

Research

Tissue repair and regeneration, Myelopoesis, resolution mechanisms, GPCR biology, innate immunity, lipid mediators

Cardiovascular Models, Infectious Disease and Inflammation Models, Musculoskeletal Models

Interests

My research interests are in understanding the biology of a novel class of essential fatty acid derived molecules termed as specilized pro-resolving mediators in regulating innate immunity and reparative mechanisms. We are developing and using new in vitro organ-chip models, including bone marrow and joint models, for understanding disease and testing potential therapeutics.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2025

Correction: RvE1 attenuates polymicrobial sepsis-induced cardiac dysfunction and enhances bacterial clearance
Chen J, Purvis GSD, Collotta D, AI Zoubi S, Sugimoto MA, Cacace A, Martin L, Colas RA et al.
Frontiers in Immunology, Frontiers Media Sa vol. 16 
31-07-2025
Intracellular and nuclear CXCR4 signaling promotes terminal erythroblast differentiation and enucleation
Gutjahr JC, Hub E, Anderson CA, Samus M, Artinger K, Gomez EA, Ratswohl C, Wickli N et al.
Science Signaling, American Association For The Advancement of Science (Aaas) vol. 18 (891) 
17-06-2025
Eosinophils and Bioactive Lipid Mediators Regulate Skin Inflammation and Cancer Growth
Malactou C, Hayes M, Zhang T, Ward S, Harwood C, Dalli J, Strid J
Journal of Investigative Dermatology, Elsevier Bv 
01-05-2025
Formyl-peptide receptor type 2 activation mitigates heart and lung damage in inflammatory arthritis
Margraf A, Chen J, Christoforou M, Claria-Ribas P, Henriques Schneider A, Cecconello C, Bu W, Imbert PRC et al.
Embo Molecular Medicine, Springer Science and Business Media Llc vol. 17 (5), 1153-1183.  
03-04-2025
Targeting Inflammatory Imbalance in Chronic Kidney Disease: Focus on Anti-Inflammatory and Resolution Mediators
Rispoli RM, Popolo A, De Fabrizio V, d’Emmanuele di Villa Bianca R, Autore G, Dalli J, Marzocco S
International Journal of Molecular Sciences, Mdpi Ag vol. 26 (7), 3072-3072.  
27-03-2025
Herring roe PLs promote SPM biosynthesis in macrophages and a keratinocyte/fibroblast co-culture as model of psoriasis
Ringheim-Bakka TA, Saliani A, Østbye T-KK, Mildenberger J, Dooley M, Busygina M, Pedersen ME, Solberg NT et al.
In Cold Spring Harbor Laboratory 
24-02-2025
Formyl-peptide receptor type 2 activation mitigates secondary organ damage in inflammatory arthritis
Margraf A, Chen J, Christoforou M, Claria-Ribas P, Schneider AH, Cecconello C, Bu W, Imbert PRC et al.
In Cold Spring Harbor Laboratory 
08-02-2025
Specialized pro-resolving lipid mediators in gut immunophysiology: from dietary precursors to inflammation resolution
Albuquerque-Souza E, Dalli J
Current Opinion in Clinical Nutrition &Amp; Metabolic Care, Ovid Technologies (Wolters Kluwer Health) vol. 28 (2), 96-103.  
13-01-2025
Pre-stimulation of Precision-Cut bovine udder slices with zymosan before LPS exposure indicates indicators for trained immunity
Filor V, Myslinska J, Saliani A, Dalli J, Steinbach S, Olinga P, Bäumer W, Werling D
In Cold Spring Harbor Laboratory 
08-01-2025
Dysregulation of lipid mediators in patients with frequent exacerbations of COPD
Fisk M, Gomez EA, Sun Y, Mickute M, McEniery C, Cockcroft JR, Bolton C, Fuld J et al.
Erj Open Research, European Respiratory Society (Ers) vol. 11 (2), 00950-2023.  
08-01-2025

2024

Development and Validation of Methodologies for the Identification of Specialized Pro-Resolving Lipid Mediators and Classic Eicosanoids in Biological Matrices
Dooley M, Saliani A, Dalli J
Journal of The American Society For Mass Spectrometry, American Chemical Society (Acs) vol. 35 (10), 2331-2343.  
10-09-2024
An LGR6 frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections
Gomez EA, De Matteis R, Udomjarumanee P, Munroe PB, Dalli J
Blood, American Society of Hematology vol. 144 (4), 420-434.  
25-07-2024
The endocannabinoid anandamide activates pro‐resolving pathways in human primary macrophages by engaging both CB2 and GPR18 receptors
Leuti A, Fava M, Forte G, Pellegrini N, Oddi S, Scipioni L, Gomez EA, Dalli J et al.
The Faseb Journal, Wiley vol. 38 (10) 
27-05-2024
Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and proinflammatory factors
Rodrigues-Diez R, Ballesteros-Martinez C, Moreno-Carriles RM, Nistal F, Díaz del Campo LS, Cachofeiro V, Dalli J, García-Redondo AB et al.
Biomedicine &Amp; Pharmacotherapy, Elsevier Bv vol. 174, 116564-116564.  
01-05-2024
Resolvin T4 enhances macrophage cholesterol efflux to reduce vascular disease
Walker ME, De Matteis R, Perretti M, Dalli J
Nature Communications, Springer Science and Business Media Llc vol. 15 (1) 
05-02-2024
Addendum: Resolvins suppress tumor growth and enhance cancer therapy
Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR et al.
Journal of Experimental Medicine, Rockefeller University Press vol. 221 (3) 
31-01-2024
Corrigendum: Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion
Aguirre GA, Goulart MR, Bank BPT, Dalli J, Kocher HM
Frontiers in Immunology, Frontiers Media Sa vol. 15 
24-01-2024

2023

Efferocyte‐Derived MCTRs Metabolically Prime Macrophages for Continual Efferocytosis via Rac1‐Mediated Activation of Glycolysis
Koenis DS, de Matteis R, Rajeeve V, Cutillas P, Dalli J
Advanced Science, Wiley vol. 11 (7) 
08-12-2023
The Annexin-A1 mimetic RTP-026 promotes acute cardioprotection through modulation of immune cell activation
Chen J, Oggero S, Cecconello C, Dalli J, Hayat H, Hjiej Andaloussi A, Sanni S, Jonassen TEN et al.
Pharmacological Research, Elsevier Bv vol. 198, 107005-107005.  
01-12-2023
Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion
Aguirre GA, Goulart MR, Dalli J, Kocher HM
Frontiers in Immunology, Frontiers Media Sa vol. 14 
16-11-2023
Reply to: Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples
Dalli J, Gomez EA
Nature Communications, Springer Science and Business Media Llc vol. 14 (1) 
10-11-2023
Stereoselective Synthesis, Pro-resolution, and Anti-inflammatory Actions of RvD5n‑3 DPA
Ervik K, Reinertsen AF, Koenis DS, Dalli J, Hansen TV
Journal of Natural Products, American Chemical Society (Acs) vol. 86 (11), 2546-2553.  
25-10-2023
Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice
Laiglesia LM, Escoté X, Sáinz N, Felix-Soriano E, Santamaría E, Collantes M, Fernández-Galilea M, Colón-Mesa I et al.
Molecular Metabolism, Elsevier Bv vol. 74, 101749-101749.  
01-08-2023
Author Correction: A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae
Ramirez JL, de Almeida Oliveira G, Calvo E, Dalli J, Colas RA, Serhan CN, Ribeiro JM, Barillas-Mury C
Nature Communications, Springer Science and Business Media Llc vol. 14 (1) 
18-07-2023
Correction: A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults
Mai NTH, Dobbs N, Phu NH, Colas RA, Thao LTP, Thuong NTT, Nghia HDT, Hanh NHH et al.
Elife, Elife Sciences Publications, Ltd vol. 12 
21-03-2023
Mistakes in the re-analysis of lipidomic data obtained from a human model of resolving inflammation lead to erroneous conclusions
Dalli J
In Cold Spring Harbor Laboratory 
15-03-2023
Pro-inflammatory and pro-resolving lipid mediators of inflammation in HIV: effect of aspirin intervention
Dalli J, Kitch D, O'Brien MP, Hunt PW, Funderburg N, Moisi D, Gupta A, Brown TT et al.
Ebiomedicine, Elsevier Bv vol. 89, 104468-104468.  
01-03-2023
Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al.
Jci Insight, American Society For Clinical Investigation vol. 8 (3) 
08-02-2023
Resolution Pharmacology: Focus on Pro-Resolving Annexin A1 and Lipid Mediators for Therapeutic Innovation in Inflammation
Perretti M, Dalli J
Annual Review of Pharmacology and Toxicology, Annual Reviews vol. 63 (1), 449-469.  
20-01-2023
Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans
Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC et al.
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 133 (2) 
17-01-2023
Resolvin D2 Attenuates Cardiovascular Damage in Angiotensin II-Induced Hypertension
Díaz del Campo LS, García-Redondo AB, Rodríguez C, Zaragoza C, Duro-Sánchez S, Palmas F, de Benito-Bueno A, Socuéllamos PG et al.
Hypertension, Ovid Technologies (Wolters Kluwer Health) vol. 80 (1), 84-96.  
01-01-2023

2022

Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation
Flak MB, Koenis DS, Gonzalez-Nunez M, Chopo-Pizarro A, Dalli J
Biochemical Pharmacology, Elsevier vol. 207 
15-11-2022
LsfA, a 1-Cys Peroxiredoxin involved with Pseudomonas aeruginosa virulence: Structure, biochemical activity, and its influence in inflammation/resolution
Silva RA, Domingos R, Trujillo M, Filho A, Oliveira C, Baldini R, Dalli J, Netto L
Free Radical Biology and Medicine, Elsevier Bv vol. 192, 117-117.  
01-11-2022
Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis

Jci Insight, American Society For Clinical Investigation vol. 7 (20) 
24-10-2022
Structure elucidation and biological evaluations of sulfido-conjugated specialized pro-resolving mediators
Dalli J, Rodriguez A, Spur B, Serhan C
2022 AOCS Annual Meeting & Expo. 
29-09-2022
Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit
Caravaca AS, Gallina AL, Tarnawski L, Shavva VS, Colas RA, Dalli J, Malin SG, Hult H et al.
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 119 (22) 
27-05-2022
Distinct immune profiles of HIV‐infected subjects are linked to specific lipid mediator signature
Sips M, Gerlo S, De Clercq L, Gomez EA, Colas RA, Dalli J, Vandekerckhove L
Immunity, Inflammation and Disease, Wiley vol. 10 (6) 
27-05-2022
MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis

Ebiomedicine, Elsevier Bv vol. 79, 103974-103974.  
01-05-2022
Lipoxin A4 Mediates Mesenchymal Stromal Cell Therapeutic Effects in Sepsis
Keogh A, Clarke J, Rabani R, Dalli J, Godson C, Curley G
American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. 
01-05-2022
Evidence for the presence and diagnostic utility of SPM in human peripheral blood
Dalli J, Gomez EA, Serhan CN
In Cold Spring Harbor Laboratory 
30-04-2022
Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions
Dyall SC, Balas L, Bazan NG, Brenna JT, Chiang N, da Costa Souza F, Dalli J, Durand T et al.
Progress in Lipid Research, Elsevier Bv vol. 86, 101165-101165.  
01-04-2022
Utility of the Specialized Pro-Resolving Mediators as Diagnostic and Prognostic Biomarkers in Disease
Dalli J, Gomez EA, Jouvene CC
Biomolecules, Mdpi Ag vol. 12 (3), 353-353.  
23-02-2022
Lipid mediator n‐3 docosapentaenoic acid‐derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G‐protein‐coupled receptor
Mikroulis A, Ledri M, Ruffolo G, Palma E, Sperk G, Dalli J, Vezzani A, Kokaia M
The Faseb Journal, Wiley vol. 36 (3) 
21-02-2022
20‐hydroxyeicosatetraenoic acid (20‐HETE) is a pivotal endogenous ligand for TRPV1‐mediated neurogenic inflammation in the skin
Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Montalvo Moreira SA, Rathod K, Chen J et al.
British Journal of Pharmacology, Wiley vol. 179 (7), 1450-1469.  
14-02-2022
Aspirin activates resolution pathways to reprogram T cell and macrophage responses in colitis-associated colorectal cancer
De Matteis R, Flak MB, Gonzalez-Nunez M, Austin-Williams S, Palmas F, Colas RA, Dalli J
Science Advances, American Association For The Advancement of Science (Aaas) vol. 8 (5) 
04-02-2022
Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis
Kraft JD, Blomgran R, Bergström I, Soták M, Clark M, Rani A, Rajan MR, Dalli J et al.
The Faseb Journal, Wiley vol. 36 (3) 
01-02-2022
MCTR3 reprogramming arthritic monocytes to exert pro-resolving and tissue-protective functions in inflammatory arthritis

 
01-01-2022

2021

Stereoselective Synthesis, Configurational Assignment and Biological Evaluations of the Lipid Mediator RvD2n‐3 DPA
Reinertsen AF, Primdahl KG, De Matteis R, Dalli J, Hansen TV
Chemistry – a European Journal, Wiley vol. 28 (7) 
28-12-2021
Differential Lipid Mediator Involvement in the Different Forms of Genetic Frontotemporal Dementia: Novel Insights into Neuroinflammation
Sogorb-Esteve A, Colas RA, Dalli J, Rohrer JD
Journal of Alzheimer's Disease, Sage Publications vol. 84 (1), 283-289.  
26-10-2021
Lipid Mediator n-3 Docosapentaenoic Acid-Derived Protectin D1­(PD1n-3DPA) Enhances Synaptic Inhibition of Hippocampal Principal Neurons by Interaction with a G-Protein Coupled Receptor
Mikroulis A, Ledri M, Ruffolo G, Palma E, Sperk G, Dalli J, Vezzani A, Kokaia M
In Springer Science and Business Media Llc 
16-09-2021
Dysregulated Maresin Concentrations in Plasma and Nasal Secretions From Patients With Chronic Rhinosinusitis
Beegun I, Koenis DS, Alusi G, Dalli J
Frontiers in Immunology, Frontiers vol. 12 
31-08-2021
Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients
Palmas F, Clarke J, Colas RA, Gomez EA, Keogh A, Boylan M, McEvoy N, McElvaney OJ et al.
Plos One, Public Library of Science (Plos) vol. 16 (8), e0256226-e0256226.  
26-08-2021
Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in COVID-19
Koenis DS, Beegun I, Jouvene CC, Aguirre GA, Souza PR, Gonzalez-Nunez M, Ly L, Pistorius K et al.
Circulation Research, Ovid Technologies (Wolters Kluwer Health) vol. 129 (4) 
06-08-2021
Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis
Piattini F, Matsushita M, Muri J, Bretscher P, Feng X, Freigang S, Dalli J, Schneider C et al.
European Journal of Immunology, Wiley vol. 51 (10), 2417-2429.  
29-07-2021
Loss of 15-lipoxygenase disrupts Treg differentiation altering their pro-resolving functions
Marques RM, Gonzalez-Nunez M, Walker ME, Gomez EA, Colas RA, Montero-Melendez T, Perretti M, Dalli J
Cell Death &Amp; Differentiation, Springer Science and Business Media Llc vol. 28 (11), 3140-3160.  
27-05-2021
14,17,18-Trihydroxy-Eicosatetraenoic Acid: A Novel Pro-Resolving Lipid Mediator from Marine Microalgae
Jagusch H, Werner M, Koenis D, Dalli J, Werz O, Pohnert G
Acs Pharmacology & Translational Science, American Chemical Society (Acs) vol. 4 (3), 1188-1194.  
27-05-2021
Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education
Rossaint J, Thomas K, Mersmann S, Skupski J, Margraf A, Tekath T, Jouvene CC, Dalli J et al.
Journal of Experimental Medicine, Rockefeller University Press vol. 218 (7) 
20-05-2021
Changes in brown adipose tissue lipid mediator signatures with aging, obesity, and DHA supplementation in female mice
Félix‐Soriano E, Sáinz N, Gil‐Iturbe E, Collantes M, Fernández‐Galilea M, Castilla‐Madrigal R, Ly L, Dalli J et al.
The Faseb Journal, Wiley vol. 35 (6) 
07-05-2021
Lipoxin A4 as a Mediator of Mesenchymal Stromal Cell Therapeutic Effects in Pulmonary Sepsis
Keogh A, Clarke J, Rabani R, Dalli J, Curley GF
American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. 
01-05-2021
Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs
Sokal DM, McSloy A, Donegà M, Kirk J, Colas RA, Dolezalova N, Gomez EA, Gupta I et al.
Frontiers in Immunology, Frontiers Media Sa vol. 12 
29-03-2021

2020

Protective activities of distinct omega-3 enriched oils are linked to their ability to upregulate specialized pro-resolving mediators
Sobrino A, Walker ME, Colas RA, Dalli J
Plos One, Public Library of Science (Plos) vol. 15 (12), e0242543-e0242543.  
16-12-2020
HIF1α activation in dendritic cells under sterile conditions promotes an anti-inflammatory phenotype through accumulation of intracellular lipids
Wood EG, Macdougall CE, Blythe H, Clément M, Colas RA, Dalli J, Marelli-Berg F, Longhi MP
Scientific Reports, Springer Nature vol. 10 (1) 
30-11-2020
Methodologies and Procedures Employed in the Identification and Quantitation of Lipid Mediators via LC-MS/MS
Colas RA, Gomez EA, Dalli J
In Springer Science and Business Media Llc 
28-10-2020
Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis

Nature Communications, Springer Science and Business Media Llc vol. 11 (1) 
27-10-2020
The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections
Souza PR, Walker ME, Goulding NJ, Dalli J, Perretti M, Norling LV
Frontiers in Immunology, Frontiers Media Sa vol. 11 
29-09-2020
Editorial: Role of Blood Cells in Inflammatory and Vascular Disorders
Brancaleone V, Dalli J, d’Emmanuele di Villa Bianca R, Pace S
Frontiers in Pharmacology, Frontiers Media Sa vol. 11 
11-09-2020
RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance
Chen J, Purvis GSD, Collotta D, Al Zoubi S, Sugimoto MA, Cacace A, Martin L, Colas RA et al.
Frontiers in Immunology, Frontiers Media Sa vol. 11 
02-09-2020
Treatment With a Marine Oil Supplement Alters Lipid Mediators and Leukocyte Phenotype in Healthy Patients and Those With Peripheral Artery Disease
Schaller MS, Chen M, Colas RA, Sorrentino TA, Lazar AA, Grenon SM, Dalli J, Conte MS
Journal of The American Heart Association, Ovid Technologies (Wolters Kluwer Health) vol. 9 (15) 
04-08-2020
ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins
Ruhanen H, Haridas PAN, Minicocci I, Taskinen JH, Palmas F, di Costanzo A, D'Erasmo L, Metso J et al.
Biochimica Et Biophysica Acta (Bba) - Molecular and Cell Biology of Lipids, Elsevier Bv vol. 1865 (7), 158679-158679.  
01-07-2020
Imbalance of proresolving lipid mediators in persistent allodynia dissociated from signs of clinical arthritis
Allen BL, Montague-Cardoso K, Simeoli R, Colas RA, Oggero S, Vilar B, McNaughton PA, Dalli J et al.
Pain, Ovid Technologies (Wolters Kluwer Health) vol. 161 (9), 2155-2166.  
04-05-2020
Immune Regulatory Mediators in Plasma from Patients With Acute Decompensation Are Associated With 3-Month Mortality
Becares N, Härmälä S, China L, Colas RA, Maini AA, Bennet K, Skene SS, Shabir Z et al.
Clinical Gastroenterology and Hepatology, Elsevier Bv vol. 18 (5), 1207-1215.e6.  
01-05-2020
A combination of LCPUFA ameliorates airway inflammation in asthmatic mice by promoting pro-resolving effects and reducing adverse effects of EPA
Fussbroich D, Colas RA, Eickmeier O, Trischler J, Jerkic SP, Zimmermann K, Göpel A, Schwenger T et al.
Mucosal Immunology, Elsevier Bv vol. 13 (3), 481-492.  
01-05-2020
Lipid mediators of inflammation and Resolution in individuals with tuberculosis and tuberculosis-Diabetes
Shivakoti R, Dalli J, Kadam D, Gaikwad S, Barthwal M, Colas RA, Mazzacuva F, Lokhande R et al.
Prostaglandins &Amp; Other Lipid Mediators, Elsevier Bv vol. 147, 106398-106398.  
01-04-2020
Enzymatic studies with 3-oxa n-3 DPA
Pangopoulos MK, Nolsøe JMN, Antonsen SG, Colas RA, Dalli J, Aursnes M, Stenstrøm Y, Hansen TV
Bioorganic Chemistry, Elsevier Bv vol. 96, 103653-103653.  
01-03-2020
Plant‐ and Fish‐Derived n‐3 PUFAs Suppress Citrobacter Rodentium–Induced Colonic Inflammation
Määttänen P, Lurz E, Botts SR, Wu RY, Robinson SC, Yeung CW, Colas R, Li B et al.
Molecular Nutrition &Amp; Food Research, Wiley vol. 64 (6) 
12-02-2020
Stereoselective synthesis of MaR2n-3 DPA
Sønderskov J, Tungen JE, Palmas F, Dalli J, Serhan CN, Stenstrøm Y, Vidar Hansen T
Tetrahedron Letters, Elsevier Bv vol. 61 (7), 151510-151510.  
01-02-2020
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway
Wilcz‐Villega E, Carter E, Ironside A, Xu R, Mataloni I, Holdsworth J, Jones W, Moreno Béjar R et al.
Embo Molecular Medicine, Springer Nature vol. 12 (2) 
13-01-2020
Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses
Souza PR, Marques RM, Gomez EA, Colas RA, De Matteis R, Zak A, Patel M, Collier DJ et al.
Circulation Research, Ovid Technologies (Wolters Kluwer Health) vol. 126 (1), 75-90.  
03-01-2020
CFTR ABLATION BY CRISPR/CAS9 IMPAIRS THE PRODUCTION OF PRO-RESOLVING LIPID MEDIATORS BY HUMAN AIRWAY EPITHELIAL CELLS
Plebani R, Colas RA, Mattoscio D, Trerotola M, Gomez EA, Isopi E, Castagnozzi S, Dalli J et al.
 
01-01-2020

2019

GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections
Flak MB, Koenis DS, Sobrino A, Smith J, Pistorius K, Palmas F, Dalli J
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 130 (1), 359-373.  
03-12-2019
Addendum: Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n−3 DPA
Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN et al.
Chemistry – a European Journal, Wiley vol. 25 (66), 15212-15212.  
07-11-2019
Proresolving Mediators LXB4 and RvE1 Regulate Inflammation in Stromal Cells from Patients with Shoulder Tendon Tears
Dakin SG, Colas RA, Wheway K, Watkins B, Appleton L, Rees J, Gwilym S, Little C et al.
The American Journal of Pathology, Elsevier Bv vol. 189 (11), 2258-2268.  
01-11-2019
Proresolving mediator profiles in cerebrospinal fluid are linked with disease severity and outcome in adults with tuberculous meningitis
Colas RA, Nhat LTH, Thuong NTT, Gómez EA, Ly L, Thanh HH, Mai NTH, Phu NH et al.
The Faseb Journal, Wiley vol. 33 (11), 13028-13039.  
05-10-2019
Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells
Holopainen M, Colas RA, Valkonen S, Tigistu-Sahle F, Hyvärinen K, Mazzacuva F, Lehenkari P, Käkelä R et al.
Biochimica Et Biophysica Acta (Bba) - Molecular and Cell Biology of Lipids, Elsevier Bv vol. 1864 (10), 1350-1362.  
01-10-2019
A Single Injection of Docosahexaenoic Acid Induces a Pro-Resolving Lipid Mediator Profile in the Injured Tissue and a Long-Lasting Reduction in Neurological Deficit after Traumatic Brain Injury in Mice
Thau-Zuchman O, Ingram R, Harvey GG, Cooke T, Palmas F, Pallier PN, Brook J, Priestley JV et al.
Journal of Neurotrauma, Mary Ann Liebert vol. 37 (1), 66-79.  
06-09-2019
Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA
Nesman JI, Gangestad Primdahl K, Tungen JE, Palmas F, Dalli J, Hansen TV
Molecules, Mdpi Ag vol. 24 (18), 3228-3228.  
05-09-2019
Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules
Valkonen S, Holopainen M, Colas RA, Impola U, Dalli J, Käkelä R, Siljander PR-M, Laitinen S
Biochimica Et Biophysica Acta (Bba) - Molecular and Cell Biology of Lipids, Elsevier Bv vol. 1864 (8), 1168-1182.  
01-08-2019
Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction
Fosshaug LE, Colas RA, Anstensrud AK, Gregersen I, Nymo S, Sagen EL, Michelsen A, Vinge LE et al.
Ebiomedicine, Elsevier Bv vol. 46, 264-273.  
01-08-2019
Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis

Jci Insight, American Society For Clinical Investigation vol. 4 (13) 
11-07-2019
Tendon cells isolated from patients with persistent shoulder tendinopathy show dysregulated resolution responses
Dakin SG, Colas RA, Dean BJF, Wheway K, Watkins B, Dalli J, Carr AJ
Translational Sports Medicine, Wiley vol. 2 (4), 173-176.  
21-06-2019
Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock
Sordi R, Chiazza F, Collotta D, Migliaretti G, Colas RA, Vulliamy P, Brohi K, Dalli J et al.
Annals of Surgery, Ovid Technologies (Wolters Kluwer Health) vol. 273 (5), 1012-1021.  
07-06-2019
Pro-Resolving Mediator Profiles And 5-Lipoxygenase Activity In Cerebrospinal Fluid Correlate with Disease Severity and Outcome in Adults with Tuberculous Meningitis
Colas RA, Nhat LTH, Thuong NTT, Cifuentes EAG, Ly L, Thanh HH, Phu NH, Mai NTH et al.
In Cold Spring Harbor Laboratory 
16-04-2019
Proresolving mediators LXB4 and RvE1 regulate inflammation in stromal cells from patients with shoulder tendon tears
Dakin SG, Colas RA, Wheway K, Watkins B, Appleton L, Rees J, Gwilym S, Little C et al.
In Cold Spring Harbor Laboratory 
11-04-2019
FRI-109-Increased plasma leukotriene B4 in decompensated cirrhosis associates with disease progression and leads to increased skin window neutrophil infiltration
Becares N, Maini AA, Colas RA, Dalli J, Gilroy DW, O’brien A
 
01-04-2019
15‐Epi‐Lxa\n 4\n and MaR1 counter inflammation in stromal cells from patients with Achilles tendinopathy and rupture
Dakin SG, Colas RA, Newton J, Gwilym S, Jones N, Reid HAB, Wood S, Appleton L et al.
The Faseb Journal, Wiley vol. 33 (7), 8043-8054.  
27-03-2019
Leukocytes from obese individuals exhibit an impaired SPM signature
López-Vicario C, Titos E, Walker ME, Alcaraz-Quiles J, Casulleras M, Durán-Güell M, Flores-Costa R, Pérez-Romero N et al.
The Faseb Journal, Wiley vol. 33 (6), 7072-7083.  
06-03-2019
Novel n-3 Docosapentaneoic Acid-Derived Pro-resolving Mediators Are Vasculoprotective and Mediate the Actions of Statins in Controlling Inflammation
Dalli J, Pistorius K, Walker ME
, Springer International Publishing, 65-75.  
01-01-2019
Proresolving mediators counter inflammation in stromal cells from patients with Achilles tendon disease
Dakin SG, Colas RA, Newton J, Gwilym S, Jones N, Reid HAB, Wood S, Appleton L et al.
 
01-01-2019
Pro-resolving mediator profiles and 5-lipoxygenase activity in cerebrospinal fluids correlate with disease severity and outcomes in adults with tuberculosis meningitis
Colas RA, Thwaites GE, Thuong NT, Ly L, Phu NH, Ramakrishnan L, Mai NT, Dalli J
 
01-01-2019

2018

Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n−3 DPA
Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN et al.
Chemistry – a European Journal, Wiley vol. 25 (6), 1476-1480.  
20-12-2018
New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration
Serhan CN, Chiang N, Dalli J
Molecular Aspects of Medicine, Elsevier Bv vol. 64, 1-17.  
01-12-2018
ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages
Laguna-Fernandez A, Checa A, Carracedo M, Artiach G, Petri MH, Baumgartner R, Forteza MJ, Jiang X et al.
Circulation, Ovid Technologies (Wolters Kluwer Health) vol. 138 (16), 1693-1705.  
16-10-2018
n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis
Frigerio F, Pasqualini G, Craparotta I, Marchini S, van Vliet EA, Foerch P, Vandenplas C, Leclercq K et al.
Brain, Oxford University Press (Oup) 
10-10-2018
Identification and structure elucidation of the pro‐resolving mediators provides novel leads for resolution pharmacology
Dalli J, Serhan CN
British Journal of Pharmacology, Wiley vol. 176 (8), 1024-1037.  
03-06-2018
PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function
Pistorius K, Souza PR, De Matteis R, Austin-Williams S, Primdahl KG, Vik A, Mazzacuva F, Colas RA et al.
Cell Chemical Biology, Elsevier Bv vol. 25 (6), 749-760.e9.  
01-06-2018
Albumin Counteracts Immune-Suppressive Effects of Lipid Mediators in Patients With Advanced Liver Disease
China L, Maini A, Skene SS, Shabir Z, Sylvestre Y, Colas RA, Ly L, Becares Salles N et al.
Clinical Gastroenterology and Hepatology, Elsevier Bv vol. 16 (5), 738-747.e7.  
01-05-2018
Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2
Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F et al.
Infection and Immunity, American Society For Microbiology vol. 86 (4) 
01-04-2018
Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli–driven acute inflammation
Motwani MP, Colas RA, George MJ, Flint JD, Dalli J, Richard-Loendt A, De Maeyer RPH, Serhan CN et al.
Jci Insight, American Society For Clinical Investigation vol. 3 (6) 
22-03-2018
Impaired Production and Diurnal Regulation of Vascular RvD\n n-3 DPA\n Increase Systemic Inflammation and Cardiovascular Disease
Colas RA, Souza PR, Walker ME, Burton M, Zasłona Z, Curtis AM, Marques RM, Dalli J
Circulation Research, Ovid Technologies (Wolters Kluwer Health) vol. 122 (6), 855-863.  
16-03-2018
New maresin conjugates in tissue regeneration pathway counters leukotriene D4–stimulated vascular responses
Chiang N, Riley IR, Dalli J, Rodriguez AR, Spur BW, Serhan CN
The Faseb Journal, Wiley vol. 32 (7), 4043-4052.  
28-02-2018
A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults
Mai NTH, Dobbs N, Phu NH, Colas RA, Thao LTP, Thuong NTT, Nghia HDT, Hanh NHH et al.
Elife, Elife Sciences Publications, Ltd vol. 7 
27-02-2018
Endogenously generated arachidonate‐derived ligands for TRPV1 induce cardiac protection in sepsis
Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J et al.
The Faseb Journal, Wiley vol. 32 (7), 3816-3831.  
20-02-2018
Immunoresolvents signaling molecules at intersection between the brain and immune system
Dalli J, Serhan CN
Current Opinion in Immunology, Elsevier Bv vol. 50, 48-54.  
01-02-2018
Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis
Dalli J, Colas RA, Walker ME, Serhan CN
, Springer New York, 59-72.  
01-01-2018
Omega-3 Fatty Acids and Resolution of Inflammation
Dalli J
 
01-01-2018
Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increases Systemic Inflammation and Cardiovascular Disease
Dalli J, Colas R, de Souza PRS
 
01-01-2018

2017

Does promoting resolution instead of inhibiting inflammation represent the new paradigm in treating infections?
Dalli J
Molecular Aspects of Medicine, Elsevier Bv vol. 58, 12-20.  
01-12-2017
Resolvins suppress tumor growth and enhance cancer therapy
Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR et al.
Journal of Experimental Medicine, Rockefeller University Press vol. 215 (1), 115-140.  
30-11-2017
The novel lipid mediator PD1n-3 DPA: An overview of the structural elucidation, synthesis, biosynthesis and bioactions
Hansen TV, Dalli J, Serhan CN
Prostaglandins &Amp; Other Lipid Mediators, Elsevier Bv vol. 133, 103-110.  
01-11-2017
Pro-Resolving Mediators in Regulating and Conferring Macrophage Function
Dalli J, Serhan CN
Frontiers in Immunology, Frontiers Media Sa vol. 8 
01-11-2017
Prolonged immune alteration following resolution of acute inflammation in humans
Motwani MP, Newson J, Kwong S, Richard-Loendt A, Colas R, Dalli J, Gilroy DW
Plos One, Public Library of Science (Plos) vol. 12 (10), e0186964-e0186964.  
26-10-2017
NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B4Synthesis
Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon J-S, Shinohara M et al.
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society vol. 196 (6), 713-726.  
15-09-2017
Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy
Dakin SG, Ly L, Colas RA, Oppermann U, Wheway K, Watkins B, Dalli J, Carr AJ
Scientific Reports, Springer Science and Business Media Llc vol. 7 (1) 
08-09-2017
13‐Series resolvins mediate the leukocyte‐platelet actions of atorvastatin and pravastatin in inflammatory arthritis
Walker ME, Souza PR, Colas RA, Dalli J
The Faseb Journal, Wiley vol. 31 (8), 3636-3648.  
01-08-2017
Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarming
Reátegui E, Jalali F, Khankhel AH, Wong E, Cho H, Lee J, Serhan CN, Dalli J et al.
Nature Biomedical Engineering, Springer Science and Business Media Llc vol. 1 (7) 
30-06-2017
Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid
Vik A, Dalli J, Hansen TV
Bioorganic &Amp; Medicinal Chemistry Letters, Elsevier Bv vol. 27 (11), 2259-2266.  
01-06-2017
Characterizing the anti-inflammatory and tissue protective actions of a novel Annexin A1 peptide
Perretti M, Di Filippo C, D’Amico M, Dalli J
Plos One, Public Library of Science (Plos) vol. 12 (4), e0175786-e0175786.  
13-04-2017
Protectin D1\n n-3 DPA\n and resolvin D5\n n-3 DPA\n are effectors of intestinal protection
Gobbetti T, Dalli J, Colas RA, Federici Canova D, Aursnes M, Bonnet D, Alric L, Vergnolle N et al.
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 114 (15), 3963-3968.  
29-03-2017
Resolving inflammation by using nutrition therapy
Norling LV, Ly L, Dalli J
Current Opinion in Clinical Nutrition &Amp; Metabolic Care, Ovid Technologies (Wolters Kluwer Health) vol. 20 (2), 145-152.  
01-03-2017
Sex differences in the inflammatory response and inflammation-induced vascular dysfunction
Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, Gee L, Bansal J et al.
 
01-02-2017
Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes
Freire MO, Dalli J, Serhan CN, Van Dyke TE
The Journal of Immunology, Oxford University Press (Oup) vol. 198 (2), 718-728.  
15-01-2017
Macrophage Proresolving Mediators-the When and Where
Dalli J, Serhan C
In Myeloid Cells in Health and Disease, Asm Press 367-383.  
12-01-2017
Immune resolution mechanisms in inflammatory arthritis
Perretti M, Cooper D, Dalli J, Norling LV
Nature Reviews Rheumatology, Springer Science and Business Media Llc vol. 13 (2), 87-99.  
05-01-2017
Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes
Dalli J, Colas RA, Quintana C, Barragan-Bradford D, Hurwitz S, Levy BD, Choi AM, Serhan CN et al.
Critical Care Medicine, Ovid Technologies (Wolters Kluwer Health) vol. 45 (1), 58-68.  
01-01-2017
Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution
Dalli J, Colas RA, Arnardottir H, Serhan CN
Immunity, Elsevier Bv vol. 46 (1), 92-105.  
01-01-2017
Plasma lipid mediator (LM) profiling identifies hyper- and hypo-activated groups of patients with ACLF and targeted 20% human albumin solution infusion recalibrates abnormalities
China L, Maini A, Colas R, Ly L, Dalli J, Gilroy D, O'Brien A
 
01-01-2017
Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA
Primdahl KG, Tungen JE, De Souza PRS, Colas RA, Dalli J, Hansen TV, Vik A
Org. Biomol. Chem., Royal Society of Chemistry (Rsc) vol. 15 (40), 8606-8613.  
01-01-2017
PRORESOLVING ANTIINFLAMMATORY MECHANISMS ARE NOVEL POTENTIAL TARGETS AGAINST EPILEPTOGENESIS
Frigerio F, Colas R, Marchini S, van Vliet E, Foerch P, Aronica E, Perretti M, Dalli J et al.
 
01-01-2017

2016

Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation
Colas RA, Dalli J, Chiang N, Vlasakov I, Sanger JM, Riley IR, Serhan CN
The Journal of Immunology, Oxford University Press (Oup) vol. 197 (11), 4444-4452.  
01-12-2016
Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators*
Tsoyi K, Hall SRR, Dalli J, Colas RA, Ghanta S, Ith B, Coronata A, Fredenburgh LE et al.
Critical Care Medicine, Ovid Technologies (Wolters Kluwer Health) vol. 44 (12), e1236-e1245.  
01-12-2016
Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans
Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC et al.
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 127 (1), 169-182.  
28-11-2016
Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue
Titos E, Rius B, López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Lopategi A, Dalli J, Lozano JJ et al.
The Journal of Immunology, Oxford University Press (Oup) vol. 197 (8), 3360-3370.  
15-10-2016
Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages
Dalli J, Vlasakov I, Riley IR, Rodriguez AR, Spur BW, Petasis NA, Chiang N, Serhan CN
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 113 (43), 12232-12237.  
06-10-2016
Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins
Primdahl KG, Aursnes M, Walker ME, Colas RA, Serhan CN, Dalli J, Hansen TV, Vik A
Journal of Natural Products, American Chemical Society (Acs) vol. 79 (10), 2693-2702.  
05-10-2016
Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation
Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M, Serhan CN
The Journal of Immunology, Oxford University Press (Oup) vol. 197 (6), 2362-2368.  
15-09-2016
Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation
Abdulnour RE, Sham HP, Douda DN, Colas RA, Dalli J, Bai Y, Ai X, Serhan CN et al.
Mucosal Immunology, Elsevier Bv vol. 9 (5), 1278-1287.  
01-09-2016
Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses
Chiurchiù V, Leuti A, Dalli J, Jacobsson A, Battistini L, Maccarrone M, Serhan CN
Science Translational Medicine, American Association For The Advancement of Science (Aaas) vol. 8 (353) 
24-08-2016
Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia
Colby JK, Abdulnour R-EE, Sham HP, Dalli J, Colas RA, Winkler JW, Hellmann J, Wong B et al.
The American Journal of Pathology, Elsevier Bv vol. 186 (7), 1801-1813.  
01-07-2016
SAT0026 Pro-Resolving and Cartilage-Protective Actions of Resolvin D1 in Inflammatory Arthritis
Norling L, Headland S, Dalli J, Arnardottir H, Jones H, Haworth O, Serhan C, Perretti M
 
01-06-2016
AB0042 Identification of Sulfido-Conjugated Mediators That Promote Resolution of Infection and Organ Protection
Dalli J, Chiang N, Serhan C
Annals of The Rheumatic Diseases, Elsevier Bv vol. 75, 911-911.  
01-06-2016
Macrophage Proresolving Mediators—the When and Where
Dalli J, Serhan C
Microbiology Spectrum, American Society For Microbiology vol. 4 (3) 
06-05-2016
Human milk proresolving mediators stimulate resolution of acute inflammation
Arnardottir H, Orr SK, Dalli J, Serhan CN
Mucosal Immunology, Elsevier Bv vol. 9 (3), 757-766.  
01-05-2016
Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling
Elajami TK, Colas RA, Dalli J, Chiang N, Serhan CN, Welty FK
The Faseb Journal, Wiley vol. 30 (8), 2792-2801.  
27-04-2016
Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al.
Jci Insight, American Society For Clinical Investigation vol. 1 (5) 
21-04-2016
Lipid mediators and the resolution of chronic inflammation: implications for arthritis therapy
Dalli J
Osteoarthritis and Cartilage, Elsevier Bv vol. 24, S2-S2.  
01-04-2016
The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation
Ramon S, Dalli J, Sanger JM, Winkler JW, Aursnes M, Tungen JE, Hansen TV, Serhan CN
The American Journal of Pathology, Elsevier Bv vol. 186 (4), 962-973.  
01-04-2016
Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes
Wang C-W, Colas RA, Dalli J, Arnardottir HH, Nguyen D, Hasturk H, Chiang N, Van Dyke TE et al.
Infection and Immunity, American Society For Microbiology vol. 84 (3), 658-665.  
01-03-2016
Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3
Dalli J, Sanger JM, Rodriguez AR, Chiang N, Spur BW, Serhan CN
Plos One, Public Library of Science (Plos) vol. 11 (2), e0149319-e0149319.  
16-02-2016
Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance
Winkler JW, Orr SK, Dalli J, Cheng C-YC, Sanger JM, Chiang N, Petasis NA, Serhan CN
Scientific Reports, Springer Science and Business Media Llc vol. 6 (1) 
08-01-2016
Selective identification of specialized pro-resolving lipid mediators from their biosynthetic double di-oxygenation isomers
Hansen TV, Dalli J, Serhan CN
Rsc Advances, Royal Society of Chemistry (Rsc) vol. 6 (34), 28820-28829.  
01-01-2016
Specialized Pro-Resolving Mediators from Omega-3 Fatty Acids Improve Amyloid-β Phagocytosis and Regulate Inflammation in Patients with Minor Cognitive Impairment
Fiala M, Terrando N, Dalli J
Journal of Alzheimer's Disease, Sage Publications vol. 49 (4), 1191-1191.  
01-01-2016

2015

Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins
Cianci E, Recchiuti A, Trubiani O, Diomede F, Marchisio M, Miscia S, Colas RA, Dalli J et al.
Stem Cells Translational Medicine, Oxford University Press (Oup) vol. 5 (1), 20-32.  
25-11-2015
Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages
Aursnes M, Tungen JE, Colas RA, Vlasakov I, Dalli J, Serhan CN, Hansen TV
Journal of Natural Products, American Chemical Society (Acs) vol. 78 (12), 2924-2931.  
18-11-2015
Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages
Croasdell A, Thatcher TH, Kottmann RM, Colas RA, Dalli J, Serhan CN, Sime PJ, Phipps RP
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society vol. 309 (8), L888-L901.  
15-10-2015
Specialized Pro-Resolving Mediators from Omega-3 Fatty Acids Improve Amyloid-β Phagocytosis and Regulate Inflammation in Patients with Minor Cognitive Impairment
Fiala M, Terrando N, Dalli J
Journal of Alzheimer's Disease, Sage Publications vol. 48 (2), 293-301.  
09-09-2015
The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide
Dalli J, Kraft BD, Colas RA, Shinohara M, Fredenburgh LE, Hess DR, Chiang N, Welty-Wolf K et al.
American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society vol. 53 (3), 314-325.  
01-09-2015
Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections
Dalli J, Chiang N, Serhan CN
Nature Medicine, Springer Science and Business Media Llc vol. 21 (9), 1071-1075.  
03-08-2015
Identification of resolvin D2 receptor mediating resolution of infections and organ protection
Chiang N, Dalli J, Colas RA, Serhan CN
Journal of Experimental Medicine, Rockefeller University Press vol. 212 (8), 1203-1217.  
20-07-2015
Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease
Börgeson E, Johnson AMF, Lee YS, Till A, Syed GH, Ali-Shah ST, Guiry PJ, Dalli J et al.
Cell Metabolism, Elsevier Bv vol. 22 (1), 125-137.  
01-07-2015
Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function
Kain V, Ingle KA, Colas RA, Dalli J, Prabhu SD, Serhan CN, Joshi M, Halade GV
Journal of Molecular and Cellular Cardiology, Elsevier Bv vol. 84, 24-35.  
01-07-2015
A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae
Ramirez JL, de Almeida Oliveira G, Calvo E, Dalli J, Colas RA, Serhan CN, Ribeiro JM, Barillas-Mury C
Nature Communications, Springer Science and Business Media Llc vol. 6 (1) 
23-06-2015
Maresin-1 regulates type 2 innate lymphoid cells and promotes generation of regulatory T cells to limit allergic inflammation (HYP2P.336)
Krishnamoorthy N, Burkett P, Dalli J, Abdulnour R-E, Colas R, Ramon S, Phipps R, Petasis N et al.
The Journal of Immunology, Oxford University Press (Oup) vol. 194 (1_Supplement), 53.17-53.17.  
01-05-2015
The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution
Serhan CN, Chiang N, Dalli J
Seminars in Immunology, Elsevier Bv vol. 27 (3), 200-215.  
01-05-2015
Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent
Orr SK, Colas RA, Dalli J, Chiang N, Serhan CN
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society vol. 308 (9), L904-L911.  
01-05-2015
Characterization of the anti-inflammatory properties of NCX 429, a dual-acting compound releasing nitric oxide and naproxen
Amoruso A, Fresu LG, Dalli J, Miglietta D, Bardelli C, Canova DF, Perretti M, Brunelleschi S
Life Sciences, Elsevier Bv vol. 126, 28-36.  
01-04-2015
Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome
Serhan CN, Dalli J, Colas RA, Winkler JW, Chiang N
Biochimica Et Biophysica Acta (Bba) - Molecular and Cell Biology of Lipids, Elsevier Bv vol. 1851 (4), 397-413.  
01-04-2015
Novel Peptide‐Conjugated Maresins Stimulate Tissue Regeneration and Clearance of Infections in Planaria and Inflammatory Exudates
Dalli J, Chiang N, Serhan C
The Faseb Journal, Wiley vol. 29 (S1) 
01-04-2015
Suppression of Cell Debris‐Stimulated Tumor Growth by Resolvin Mediated Clearance
Sulciner M, Mudge D, Ramon S, Dalli J, Kieran M, Huang S, Serhan C, Panigrahy D
The Faseb Journal, Wiley vol. 29 (S1) 
01-04-2015
Resolvin D4 Potent Antiiinflammatory Proresolving Actions Confirmed via Total Synthesis
Winkler J, Orr S, Dalli J, Chiang N, Petasis N, Serhan C
The Faseb Journal, Wiley vol. 29 (S1) 
01-04-2015
Elucidation of Resolvin and Protectin Sulfido‐Conjugated Mediators: New Pro‐Resolving and Tissue Regenerative Pathways
Ramon S, Dalli J, Norris P, Colas R, Serhan C
The Faseb Journal, Wiley vol. 29 (S1) 
01-04-2015
Human Milk Stimulates Resolution of Acute Inflammation
Arnardottir H, Orr S, Dalli J, Serhan C
The Faseb Journal, Wiley vol. 29 (S1) 
01-04-2015
Novel proresolving and tissue‐regenerative resolvin and protectin sulfido‐conjugated pathways
Dalli J, Ramon S, Norris PC, Colas RA, Serhan CN
The Faseb Journal, Wiley vol. 29 (5), 2120-2136.  
20-02-2015
Cutting Edge: Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of Lung Inflammation
Krishnamoorthy N, Burkett PR, Dalli J, Abdulnour R-EE, Colas R, Ramon S, Phipps RP, Petasis NA et al.
The Journal of Immunology, Oxford University Press (Oup) vol. 194 (3), 863-867.  
01-02-2015

2014

Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1
Shinohara M, Kibi M, Riley IR, Chiang N, Dalli J, Kraft BD, Piantadosi CA, Choi AMK et al.
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society vol. 307 (10), L746-L757.  
15-11-2014
Proresolving Nanomedicines Activate Bone Regeneration in Periodontitis
Van Dyke TE, Hasturk H, Kantarci A, Freire MO, Nguyen D, Dalli J, Serhan CN
Journal of Dental Research, Sage Publications vol. 94 (1), 148-156.  
11-11-2014
Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective
Abdulnour R-EE, Dalli J, Colby JK, Krishnamoorthy N, Timmons JY, Tan SH, Colas RA, Petasis NA et al.
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 111 (46), 16526-16531.  
04-11-2014
Lipid Mediators in the Resolution of Inflammation
Serhan CN, Chiang N, Dalli J, Levy BD
Cold Spring Harbor Perspectives in Biology, Cold Spring Harbor Laboratory vol. 7 (2), a016311-a016311.  
30-10-2014
Correction: Corrigendum: Novel n-3 Immunoresolvents: Structures and Actions
Dalli J, Colas RA, Serhan CN
Scientific Reports, Springer Science and Business Media Llc vol. 4 (1) 
24-10-2014
Cover Picture: Total Synthesis of the Anti‐inflammatory and Pro‐resolving Lipid Mediator MaR1n−3 DPA Utilizing an sp3–sp3 Negishi Cross‐Coupling Reaction (Chem. Eur. J. 45/2014)
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV
Chemistry – a European Journal, Wiley vol. 20 (45), 14533-14533.  
23-10-2014
Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection
Dalli J, Chiang N, Serhan CN
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 111 (44) 
16-10-2014
Plasma Metabolomics in Human Pulmonary Tuberculosis Disease: A Pilot Study
Frediani JK, Jones DP, Tukvadze N, Uppal K, Sanikidze E, Kipiani M, Tran VT, Hebbar G et al.
Plos One, Public Library of Science (Plos) vol. 9 (10), e108854-e108854.  
15-10-2014
Aging Delays Resolution of Acute Inflammation in Mice: Reprogramming the Host Response with Novel Nano-Proresolving Medicines
Arnardottir HH, Dalli J, Colas RA, Shinohara M, Serhan CN
The Journal of Immunology, Oxford University Press (Oup) vol. 193 (8), 4235-4244.  
15-10-2014
Abstract 1664: Cancer progression: The failure to resolve
Sulciner ML, Mudge DK, Bielenberg DR, Benny O, Dalli J, Huang S, Serhan CN, Kieran MW et al.
 
01-10-2014
Abstract 1170: Maresin 1: a potent endogenous anti-inflammatory and pro-resolving inhibitor of primary tumor growth and metastasis
Mudge D, Kieran MW, Bielenberg D, Benny O, Dalli J, Huang S, Serhan CN, Panigrahy D
 
01-10-2014
Total Synthesis of the Anti‐inflammatory and Pro‐resolving Lipid Mediator MaR1n−3 DPA Utilizing an sp3–sp3 Negishi Cross‐Coupling Reaction
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV
Chemistry – a European Journal, Wiley vol. 20 (45), 14537-14537.  
24-09-2014
Synthesis and Anti-inflammatory and Pro-resolving Activities of 22-OH-PD1, a Monohydroxylated Metabolite of Protectin D1
Tungen JE, Aursnes M, Vik A, Ramon S, Colas RA, Dalli J, Serhan CN, Hansen TV
Journal of Natural Products, American Chemical Society (Acs) vol. 77 (10), 2241-2247.  
23-09-2014
Total Synthesis of the Anti‐inflammatory and Pro‐resolving Lipid Mediator MaR1n−3 DPA Utilizing an sp3–sp3 Negishi Cross‐Coupling Reaction
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV
Chemistry – a European Journal, Wiley vol. 20 (45), 14575-14578.  
15-09-2014
Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages
Deng B, Wang C-W, Arnardottir HH, Li Y, Cheng C-YC, Dalli J, Serhan CN
Plos One, Public Library of Science (Plos) vol. 9 (7), e102362-e102362.  
18-07-2014
15. Neutrophils in GCA
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M
Rheumatology, Oxford University Press (Oup) vol. 53 (suppl 2), i9-i9.  
01-07-2014
Cutting Edge: Parathyroid Hormone Facilitates Macrophage Efferocytosis in Bone Marrow via Proresolving Mediators Resolvin D1 and Resolvin D2
McCauley LK, Dalli J, Koh AJ, Chiang N, Serhan CN
The Journal of Immunology, Oxford University Press (Oup) vol. 193 (1), 26-29.  
01-07-2014
Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue
Colas RA, Shinohara M, Dalli J, Chiang N, Serhan CN
American Journal of Physiology-Cell Physiology, American Physiological Society vol. 307 (1), C39-C54.  
01-07-2014
ChemInform Abstract: Stereoselective Synthesis of Protectin D1: A Potent Antiinflammatory and Proresolving Lipid Mediator.
Aursnes M, Tungen JE, Vik A, Dalli J, Hansen TV
Cheminform, Wiley vol. 45 (26) 
12-06-2014
Vagus nerve controls resolution and pro-resolving mediators of inflammation
Mirakaj V, Dalli J, Granja T, Rosenberger P, Serhan CN
Journal of Experimental Medicine, Rockefeller University Press vol. 211 (6), 1037-1048.  
26-05-2014
Resolvin D1 protects from neutrophil mediated joint destruction in inflammatory arthritis (146.5)
Norling L, Headland S, Dalli J, Serhan C, Perretti M
 
01-04-2014
A novel mechanism for protecting the arthritic joint: microparticles deliver Annexin A1 into cartilage (146.8)
Headland S, Norling L, Patel H, Dalli J, Kelly S, Pitzalis C, Dell'Accio F, Perretti M
 
01-04-2014
Plasma high‐resolution metabolomic profiling reveals upregulation of specific resolvins in patients with pulmonary tuberculosis (248.3)
Frediani J, Jones D, Tukvadze N, Sanikidze E, Kipiani M, Uppal K, Kurani S, Hebbar G et al.
The Faseb Journal, Wiley vol. 28 (S1) 
01-04-2014
Total Synthesis of the Lipid Mediator PD1n-3 DPA: Configurational Assignments and Anti-inflammatory and Pro-resolving Actions
Aursnes M, Tungen JE, Vik A, Colas R, Cheng C-YC, Dalli J, Serhan CN, Hansen TV
Journal of Natural Products, American Chemical Society (Acs) vol. 77 (4), 910-916.  
27-02-2014
Investigational Analysis Reveals a Potential Role for Neutrophils in Giant-Cell Arteritis Disease Progression
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M
Circulation Research, Ovid Technologies (Wolters Kluwer Health) vol. 114 (2), 242-248.  
17-01-2014
NEUTROPHILS IN GCA
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M
 
01-01-2014
Macrophages and the Entrance of Resolution Phase Lipid Mediators
Serhan CN, Chiang N, Dalli J
In Macrophages: Biology and Role in The Pathology of Diseases, Springer New York 287-314.  
01-01-2014
Total Synthesis of the Anti-inflammatory and Pro-resolving Lipid Mediator MaR1n-3DPA Utilizing an sp3-sp3 Negishi Cross-Coupling Reaction
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV
Chemistry-a European Journal vol. 20 (45), 14575-14578.  
01-01-2014
Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator
Aursnes M, Tungen JE, Vik A, Dalli J, Hansen TV
Org. Biomol. Chem., Royal Society of Chemistry (Rsc) vol. 12 (3), 432-437.  
01-01-2014

2013

Microparticle alpha‐2‐macroglobulin enhances pro‐resolving responses and promotes survival in sepsis
Dalli J, Norling LV, Montero‐Melendez T, Canova DF, Lashin H, Pavlov AM, Sukhorukov GB, Hinds CJ et al.
Embo Molecular Medicine, Springer Science and Business Media Llc vol. 6 (1), 27-42.  
16-12-2013
Plasticity of Leukocytic Exudates in Resolving Acute Inflammation Is Regulated by MicroRNA and Proresolving Mediators
Li Y, Dalli J, Chiang N, Baron RM, Quintana C, Serhan CN
Immunity, Elsevier Bv vol. 39 (5), 885-898.  
01-11-2013
Contributions of the Three CYP1 Monooxygenases to Pro-Inflammatory and Inflammation-Resolution Lipid Mediator Pathways
Divanovic S, Dalli J, Jorge-Nebert LF, Flick LM, Gálvez-Peralta M, Boespflug ND, Stankiewicz TE, Fitzgerald JM et al.
The Journal of Immunology, Oxford University Press (Oup) vol. 191 (6), 3347-3357.  
15-09-2013
Heterogeneity in Neutrophil Microparticles Reveals Distinct Proteome and Functional Properties
Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M
Molecular &Amp; Cellular Proteomics, Elsevier Bv vol. 12 (8), 2205-2219.  
01-08-2013
Microparticles are novel effectors of immunity
Norling LV, Dalli J
Current Opinion in Pharmacology, Elsevier Bv vol. 13 (4), 570-575.  
01-08-2013
Proresolving and Tissue-Protective Actions of Annexin A1–Based Cleavage-Resistant Peptides Are Mediated by Formyl Peptide Receptor 2/Lipoxin A4 Receptor
Dalli J, Consalvo AP, Ray V, Di Filippo C, D’Amico M, Mehta N, Perretti M
The Journal of Immunology, Oxford University Press (Oup) vol. 190 (12), 6478-6487.  
15-06-2013
Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Unique Proresolving Mediator–Heme Oxygenase-1 Circuits
Chiang N, Shinohara M, Dalli J, Mirakaj V, Kibi M, Choi AMK, Serhan CN
The Journal of Immunology, Oxford University Press (Oup) vol. 190 (12), 6378-6388.  
15-06-2013
Novel n-3 Immunoresolvents: Structures and Actions
Dalli J, Colas RA, Serhan CN
Scientific Reports, Springer Science and Business Media Llc vol. 3 (1) 
05-06-2013
Neutrophil Microparticles are heterogenous in content and function
Perretti M, Dalli J, Norling LV, Melendez TM, Hinds C
 
01-04-2013
Pro‐Resolving Mediator Production by Human Phagocytes and their Transcellular Biosynthesis with Microparticles in Inflammation‐Resolution
Dalli J, Serhan C
The Faseb Journal, Wiley vol. 27 (S1) 
01-04-2013
Temporal Regulation of Pro‐Resolving Mediators and MicroRNA in Self‐Limited versus Delayed Resolution of Acute Inflammation
Li Y, Fredman G, Dalli J, Chiang N, Serhan CN
The Faseb Journal, Wiley vol. 27 (S1) 
01-04-2013
E. coli peritonitis initiates D‐series Resolvin‐metabolome
Gao F, Dalli J, Claria J, Serhan CN
The Faseb Journal, Wiley vol. 27 (S1) 
01-04-2013
Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Novel Pro‐resolving Mediators and Heme Oxygenase‐1
Shinohara M, Chiang N, Dalli J, Mirakaj V, Choi AMK, Serhan CN
The Faseb Journal, Wiley vol. 27 (S1) 
01-04-2013
Maresin 1 a Novel Macrophage n‐3 Derived Mediator is a Potent Tissue Regenerative Immunoresolvent
Dalli J, Karamnov S, Zhu M, Petasis N, Serhan CN
The Faseb Journal, Wiley vol. 27 (S1) 
01-04-2013
The novel 13S,14S‐epoxy‐maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4hydrolase (LTA4H), and shifts macrophage phenotype
Dalli J, Zhu M, Vlasenko NA, Deng B, Haeggström JZ, Petasis NA, Serhan CN
The Faseb Journal, Wiley vol. 27 (7), 2573-2583.  
15-03-2013
Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents
Dalli J, Winkler JW, Colas RA, Arnardottir H, Cheng C-YC, Chiang N, Petasis NA, Serhan CN
Chemistry &Amp; Biology, Elsevier Bv vol. 20 (2), 188-201.  
01-02-2013
Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1β, TNF-α, IL-6, and HMGB1 Expression
Sampaio ALF, Dalli J, Brancaleone V, D'Acquisto F, Perretti M, Wheatley C
Mediators of Inflammation, Wiley vol. 2013, 1-20.  
01-01-2013

2012

Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors
Montero-Melendez T, Dalli J, Perretti M
Cell Death &Amp; Differentiation, Springer Science and Business Media Llc vol. 20 (4), 567-575.  
07-12-2012
Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions
Jones CN, Dalli J, Dimisko L, Wong E, Serhan CN, Irimia D
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 109 (50), 20560-20565.  
26-11-2012
Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC–MS/MS
Giera M, Ioan-Facsinay A, Toes R, Gao F, Dalli J, Deelder AM, Serhan CN, Mayboroda OA
Biochimica Et Biophysica Acta (Bba) - Molecular and Cell Biology of Lipids, Elsevier Bv vol. 1821 (11), 1415-1424.  
01-11-2012
Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators
Dalli J, Serhan CN
Blood, American Society of Hematology vol. 120 (15), e60-e72.  
11-10-2012
Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA
Fredman G, Li Y, Dalli J, Chiang N, Serhan CN
Scientific Reports, Springer Science and Business Media Llc vol. 2 (1) 
06-09-2012
Genetic Ablation of the Fpr1 Gene Confers Protection from Smoking-Induced Lung Emphysema in Mice
Cardini S, Dalli J, Fineschi S, Perretti M, Lungarella G, Lucattelli M
American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society vol. 47 (3), 332-339.  
01-09-2012
Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat
Clària J, Dalli J, Yacoubian S, Gao F, Serhan CN
The Journal of Immunology, Oxford University Press (Oup) vol. 189 (5), 2597-2605.  
01-09-2012
Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci
Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M
Arteriosclerosis, Thrombosis, and Vascular Biology, Ovid Technologies (Wolters Kluwer Health) vol. 32 (8), 1970-1978.  
01-08-2012
Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages
Chen X, Barozzi I, Termanini A, Prosperini E, Recchiuti A, Dalli J, Mietton F, Matteoli G et al.
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 109 (42) 
16-07-2012
FPR1 Blockade And Smoking-Induced Lung Emphysema In Mice
Lucattelli M, Cardini S, Fineschi S, Dalli J, Perretti M, Lungarella G
American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. 
01-05-2012
Resolvin D1 limits PMN recruitment to inflammatory loci: receptor dependent bioactions
Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M
 
01-04-2012
Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain
Serhan CN, Dalli J, Karamnov S, Choi A, Park C, Xu Z, Ji R, Zhu M et al.
The Faseb Journal, Wiley vol. 26 (4), 1755-1765.  
17-01-2012
Annexin A1 N-Terminal Derived Peptide Ac2-26 Exerts Chemokinetic Effects on Human Neutrophils
Dalli J, Montero-Melendez T, McArthur S, Perretti M
Frontiers in Pharmacology, Frontiers Media Sa vol. 3 
01-01-2012
RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS
Norling L, Dalli J, Flower R, Serhan C, Perretti M
 
01-01-2012

2011

Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow
Dalli J, Jones CP, Cavalcanti DM, Farsky SH, Perretti M, Rankin SM
The Faseb Journal, Wiley vol. 26 (1), 387-396.  
28-09-2011
Evidence for an Anti-Inflammatory Loop Centered on Polymorphonuclear Leukocyte Formyl Peptide Receptor 2/Lipoxin A(4) Receptor and Operative in the Inflamed Microvasculature
Brancaleone V, Dalli J, Bena S, Flower RJ, Cirino G, Perretti M
J Immunol vol. 186 (8), 4905-4914.  
15-04-2011
Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation (vol 184, pg 2611, 2010)
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al.
J Immunol vol. 186 (4), 2684-2685.  
15-02-2011
RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS
Norling LV, Dalli J, Serhan CN, Perretti M
 
01-01-2011
THE INFLAMMATORY RESOLUTION PROTEIN ANNEXIN A1 AND THE PAEDIATRIC CF AIRWAY
Brown SM, Dalli J, Perretti M, Bush A, Davies JC, Lloyd CM
Pediatr Pulm, 265-266.  
01-01-2011

2010

Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature
Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F
Blood vol. 116 (20), 4288-4296.  
18-11-2010
FPR2/ALX receptor expression and internalization are critical for lipoxin A(4) and annexin-derived peptide-stimulated phagocytosis
Maderna P, Cottell DC, Toivonen T, Dufton N, Dalli J, Perretti M, Godson C
Faseb J vol. 24 (11), 4240-4249.  
01-11-2010
561 THE CINOD NCX 429 INHIBITS MICROVASCULAR INFLAMMATION THROUGH ITS NO-RELEASING PROPERTIES
Perretti M, Dalli J, Bolla M, Padron J
 
01-10-2010
Downstream Gene Activation of the Receptor ALX by the Agonist Annexin A1
Renshaw D, Montero-Melendez T, Dalli J, Kamal A, Brancaleone V, D'Acquisto F, Cirino G, Perretti M
Plos One vol. 5 (9) 
17-09-2010
Resolvin D1 limits PMN recruitment to inflammatory loci: receptor dependent bioactions
Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M
Faseb Journal vol. 24 
01-04-2010
Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al.
J Immunol vol. 184 (5), 2611-2619.  
01-03-2010
CFTR inhibition yields an inflammatory response associated with an imbalance of the Annexin-A1 pathway
Dalli J, Hayhoe RPG, Rosignoli G, Edelman A, Perretti M
Eur J Clin Invest vol. 40, 47-47.  
01-03-2010
\Super\ Annexin-A1: a novel tool to regulate neutrophil-driven inflammation?
Pederzoli-Ribeil M, Maione F, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F
 
01-01-2010
Mobilization of Annexin A1 in human polymorphonuclear leukocytes (PMN)
Brancaleone V, Dalli J, Perretti M
 
01-01-2010
CFTR Inhibition Provokes an Inflammatory Response Associated with an Imbalance of the Annexin A1 Pathway
Dalli J, Rosignoli G, Hayhoe RPG, Edelman A, Perretti M
American Journal of Pathology vol. 177 (1), 176-186.  
01-01-2010

2009

Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics
Perretti M, Dalli J
Brit J Pharmacol vol. 158 (4), 936-946.  
01-10-2009
Functional and Ultrastructural Analysis of Annexin A1 and Its Receptor in Extravasating Neutrophils during Acute Inflammation
Gastardelo TS, Damazo AS, Dalli J, Flower RJ, Perretti M, Oliani SM
The American Journal of Pathology, Elsevier Bv vol. 174 (1), 177-183.  
01-01-2009

2008

Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles
Dalli J, Norling LV, Renshaw D, Cooper D, Leung K-Y, Perretti M
Blood, American Society of Hematology vol. 112 (6), 2512-2519.  
15-09-2008

2007

Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation
Gavins FNE, Dalli J, Flower RJ, Granger DN, Perretti M
Faseb J vol. 21 (8), 1751-1758.  
01-06-2007

2006

Glueocorticoid regulated expression of the anti-inflammatory receptor ALXR.
Renshaw D, Sawmynadan P, Dalli J, Perretti M
 
06-03-2006
Disinct patterns of gene expression induced by annexin 1 activation of the ALXR receptor in HEK293 cells.
Renshaw D, Dalli J, Kamal A, Perretti M
 
01-03-2006

Pro-Resolving Lipoxin A4 Rescues Impaired Post-Ischemic Angiogenesis and Perfusion Recovery in Hyperlipidemic and Diabetic Mice
Devi D, Budikote Venkatappa MB, Mäkinen P, Örd T, Aavik E, Colas R, Dalli J, Ylä-Herttuala S
 

Grants

solid heart iconGrants of specific relevance to Predictive in vitro Models
bullet iconCharacterizing the biology of GPR173 in neutrophils
Jesmond Dalli and Mauro Perretti
£74,998 Barts and the London Charity
01-09-2025 - 31-08-2026
bullet iconPathogenesis and prevention of cardiovascular disease in prostate cancer patients undergoing hormonal treatments - the role of specialised pro-resolving lipid mediators
Prabhakar Rajan and Jesmond Dalli
£74,794 Barts and the London Charity
01-10-2024 - 30-09-2025
bullet iconSCHOOL-AGE PHYSIOLOGICAL FUNCTION FOLLOWING EARLY-LIFE STUNTING AMONG CHILDREN IN RURAL ZIMBABWE
Andrew Prendergast, Jesmond Dalli, Jonathan Grigg, Melanie Smuk, Priyanthi Dias, Li Chan and Zudin Puthucheary
£457,573 MRC Medical Research Council
01-11-2023 - 31-10-2026
bullet iconReplacement of protective activities of material provided by Lonza (1), (2) and (3)
Jesmond Dalli
£213,967 Lonza Greenwood LLC
01-12-2022 - 31-12-2029
bullet iconLipid mediator profiling in arthritic patients following splenic stimulation -US study
Jesmond Dalli
£167,168 Galvani Galvani Bioelectronics Limited
01-09-2022 - 30-06-2026

bullet iconIdentification and quantitation of lipid mediators in media from cell incubations and in oils
Jesmond Dalli
£42,022 WHRL William Harvey Research Limited
11-03-2024 - 10-09-2024
bullet iconAnalysis of lipid mediator profiling datasets
Jesmond Dalli
£7,555 WHRL William Harvey Research Limited
01-02-2024 - 31-07-2024
bullet iconExploring the potential utility of SPM in regulating phagocyte responses to limit inflammation in MI
Jesmond Dalli
£66,955 Barts and the London Charity
01-02-2024 - 31-01-2025
bullet iconEarly detection of OPSCC through Salivary Specialized Lipid Mediator Profiling
Jesmond Dalli
£65,100 Barts and the London Charity
01-10-2023 - 11-04-2025
bullet iconEstablishing human organ-chip models for the bone marrow
Jesmond Dalli
£10,020 Animal Free Research UK
01-03-2023 - 09-07-2024
bullet iconAnalysis of SPM in oils
Jesmond Dalli
£15,634 WHRL William Harvey Research Limited
21-11-2022 - 20-11-2023
bullet iconLipid Mediator Profiling In Arthritic Patients Following Splenic Stimulation -Scotland Study
Jesmond Dalli
£23,738 Galvani Galvani Bioelectronics Limited
01-09-2022 - 31-12-2023
bullet iconThe Role of Pro-Resolving Lipid Mediators and Gut-Resident Macrophages in Regulating Early-in-life Immune Imprinting and Adulthood Susceptibility to Colitis - MSCA PF-EF 2021 Dalli/Albuquerque
Jesmond Dalli
£190,380 EPSRC - EU Scheme
01-09-2022 - 31-07-2025
bullet iconInflammatory mediators and their effects on haematopoiesis in sickle cell disease
Paul Telfer, Jesmond Dalli and Hasan Rizvi
£285,082 Barts and the London Charity
01-05-2022 - 31-07-2025
bullet iconSpecialized Pro-resolving Mediators in Haematopoiesis
Jesmond Dalli and Antal Rot
£337,713 Barts and the London Charity
01-05-2022 - 30-04-2025
bullet iconSpecialised lipid mediator profiling during androgen deprivation therapy for prostate cancer
Jesmond Dalli
£10,000 William Harvey Research Foundation
01-11-2021 - 31-12-2023
bullet iconAnalysis of lipid mediator
Jesmond Dalli
£23,644 William Harvey Research Limited
05-07-2021 - 04-07-2023
bullet iconJoint Protective Actions of Omega-3 Derived Lipid Mediators
Lucy Norling and Jesmond Dalli
£231,527 Barts and the London Charity
17-04-2021 - 30-11-2023
bullet iconNewton Bhabha Fund PhD Placement - Exploring a unified pathway for the anti-atherogenic effects of adiponectin, sphingosine 1-phosphate
Jesmond Dalli
£10,200 British Council
01-04-2021 - 31-01-2023
bullet iconLipid Mediator Profling AZ - 300 samples
Jesmond Dalli
£139,039 AstraZeneca UK Limited
01-09-2019 - 29-02-2024
bullet iconA phase 2, Randomized, 3 Arm Parallel Group, Placebo and Active-Controlled Study of the Effect of PL-8177 Administered via Sub-cutaneous Injection in Healthy Male Volunteers on Inflammatory Onset and Resolution
Amrita Ahluwalia and Jesmond Dalli
£545,919 Palatin Technologies
01-05-2019 - 30-04-2022
bullet iconLipid Mediator Analytical Profiling of Product Sampler
Jesmond Dalli
£45,260 Metagenics, Inc
15-03-2019 - 14-03-2021
bullet iconPlasma Lipid Mediator Profiling - Fresenius Kabi
Jesmond Dalli
£26,972 Fresenius Kabi
06-01-2019 - 31-12-2020
bullet iconLipid mediator profiles following neuronal stimulation
Jesmond Dalli
£147,772 Galvani Galvani Bioelectronics Limited
01-11-2018 - 16-10-2020
bullet iconIdentifying novel receptor targets to control complex disease processes - ECIS Equipment
Magdalena Flak, Jesmond Dalli and Mauro Perretti
£45,000 Barts and the London Charity
01-09-2018 - 31-08-2019
bullet iconVagal Regulation of RvDn-3 DPA in Cardiovascular Protection during Inflammatory Arthritis
Jesmond Dalli
£219,163 Barts and the London Charity
01-09-2018 - 28-08-2022
bullet iconTechnology transfer of methodology for lipid mediator profiling of plasma and product samples to metagenics from institution
Jesmond Dalli
£36,938 Metagenics, Inc
01-08-2018 - 31-10-2021
bullet iconOmega-3 supplements in cardiovascular protection
Jesmond Dalli
£224,480 SP Inc. Standard Process Inc.
02-07-2018 - 30-11-2020
bullet iconProfiling SPM in marine oils and testing their pro-resolving actions
Jesmond Dalli
£53,797 SP Inc. Standard Process Inc.
04-06-2018 - 31-03-2023
bullet iconThe Role and Response of Proresolving Mediators and associated influences of miRNA in underlying inflammatory responses
Jesmond Dalli
£48,248 SP Inc. Standard Process Inc.
01-04-2018 - 30-09-2021
bullet iconCompletion of full lipid analysis of selected oils to be supplied by Metagenics : WORK ORDER 5
Jesmond Dalli
£50,000 Metagenics, Inc
01-10-2017 - 31-03-2021
bullet iconAspirin promotes SPM to resolve colon cancer
Jesmond Dalli
£82,346 Bayer AG (Charitable arm)
01-07-2017 - 30-06-2019
bullet iconSPM regulation by Fish Oil Supplements in Healthy Volunteers
Jesmond Dalli
£347,448 Metagenics, Inc
09-01-2017 - 30-09-2020
bullet iconLipid mediator profiling of plasma and product sampler
Jesmond Dalli
£160,000 Metagenics, Inc
01-01-2017 - 31-10-2022
bullet iconUsing signature Lipid mediator profiles
Jesmond Dalli
£495,006 Barts and the London Charity
01-11-2016 - 30-06-2020
bullet iconMCTRinIA ERC Starting Grant
Jesmond Dalli
£1,611,228 EU Commission - Horizon 2020
01-03-2016 - 31-08-2021
bullet iconStatin triggered novel resolvins as innovative resolution based therapeutics in arthritis
Jesmond Dalli
£1,043,548 Wellcome Trust
07-09-2015 - 20-04-2021