Publications
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Publications of specific relevance to Predictive in vitro Models
2023
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Wallis R and
Bishop CL (2023).
Death-seq and ye shall find: A novel screening strategy for dying cells. Elsevier Cell Metabolism vol. 35, (10) 1675-1676.
10.1016/j.cmet.2023.09.003![](/publications/bullet24.png)
Gorkic M, Messenger D, Wainwright L, Connelly J and
Bishop CL (2023).
P33 Investigating the utility and exploring biological targets of micro-wound healing compounds in 2D and 3D skin models. Oxford University Press (Oup) British Journal of Dermatology vol. 189, (1) e27-e27.
10.1093/bjd/ljad174.054![](/publications/bullet24.png)
Gorkic M, Messenger D, Wainwright L, Connelly J and
Bishop C (2023).
1454 Investigating the utility and exploring biological targets of micro-wound healing compounds in 2D and 3D skin models. Elsevier Journal of Investigative Dermatology vol. 143, (5)
10.1016/j.jid.2023.03.1471![](/publications/bullet24.png)
Hughes BK, Wallis R and
Bishop CL (2023).
Yearning for machine learning: applications for the classification and characterisation of senescence. Springer Nature Cell and Tissue Research vol. 394, (1) 1-16.
10.1007/s00441-023-03768-42022
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Wallis R, Milligan D, Hughes B, Mizen H, López-Domínguez JA, Eduputa U, Tyler EJ, Serrano M and
Bishop CL (2022).
Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence. Impact Journals, Llc Aging vol. 14, (10) 4220-4246.
10.18632/aging.2040722021
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Palmer A, Epton S, Crawley E, Straface M, Gammon L, Edgar MM, Xu Y, Elahi S, Chin-Aleong J, Martin JE,
Bishop CL, Knowles CH and Sanger GJ (2021).
Expression of p16 Within Myenteric Neurons of the Aged Colon: A Potential Marker of Declining Function. Frontiers in Neuroscience vol. 15, 747067-747067.
10.3389/fnins.2021.747067![](/publications/bullet24.png)
Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen-Woods C, Reglero-Real N, Stein M, Vázquez-Martínez L, Girbl T, Poston RN, Golding M, Saleeb RS, Thiriot A, von Andrian UH, Duchene J, Voisin M-B,
Bishop CL, Voehringer D, Roers A, Rot A, Lämmermann T and
Nourshargh S (2021).
Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Elsevier Immunity vol. 54, (7) 1494-1510.e7.
10.1016/j.immuni.2021.04.025![](/publications/bullet24.png)
Wallis R, Josipovic N, Mizen H, Robles‐Tenorio A, Tyler EJ, Papantonis A and
Bishop CL (2021).
Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence‐associated secretory phenotype. Wiley Journal of Extracellular Vesicles vol. 10, (4)
10.1002/jev2.12041![](/publications/bullet24.png)
Tyler EJ, del Arroyo AG, Hughes BK, Wallis R, Garbe JC, Stampfer MR, Koh J, Lowe R, Philpott MP and
Bishop CL (2021).
Early growth response 2 (EGR2) is a novel regulator of the senescence programme. Wiley Aging Cell vol. 20, (3)
10.1111/acel.133182020
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Milligan DA, Tyler EJ and
Bishop CL (2020).
Tissue engineering to better understand senescence: Organotypics come of age. Elsevier Mechanisms of Ageing and Development vol. 190,
10.1016/j.mad.2020.111261![](/publications/bullet24.png)
Wallis R, Mizen H and
Bishop CL (2020).
The bright and dark side of extracellular vesicles in the senescence-associated secretory phenotype. Elsevier Mechanisms of Ageing and Development vol. 189,
10.1016/j.mad.2020.111263![](/publications/bullet24.png)
Avelar RA, Ortega JG, Tacutu R, Tyler EJ, Bennett D, Binetti P, Budovsky A, Chatsirisupachai K, Johnson E, Murray A, Shields S, Tejada-Martinez D, Thornton D, Fraifeld VE,
Bishop CL and de Magalhães JP (2020).
A multidimensional systems biology analysis of cellular senescence in aging and disease. Springer Nature Genome Biology vol. 21, (1)
10.1186/s13059-020-01990-92019
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Gorgoulis V, Adams PD, Alimonti A, Bennett DC, Bischof O,
Bishop C, Campisi J, Collado M, Evangelou K, Ferbeyre G, Gil J, Hara E, Krizhanovsky V, Jurk D, Maier AB, Narita M, Niedernhofer L, Passos JF, Robbins PD, Schmitt CA, Sedivy J, Vougas K, von Zglinicki T, Zhou D, Serrano M and Demaria M (2019).
Cellular Senescence: Defining a Path Forward. Elsevier (Cell Press) Cell vol. 179, (4) 813-827.
10.1016/j.cell.2019.10.005![](/publications/fav.png)
Almeida FV, Gammon L, Laly AC, Pundel OJ,
Bishop CL and
Connelly JT (2019).
High‐Content Analysis of Cell Migration Dynamics within a Micropatterned Screening Platform. Wiley Advanced Biosystems 1900011-1900011.
10.1002/adbi.201900011![](/publications/bullet24.png)
Almeida FV, Gammon L, Laly AC, Pundel OJ,
Bishop CL and Connelly JT (2019).
Cell Migration Dynamics: High‐Content Analysis of Cell Migration Dynamics within a Micropatterned Screening Platform (Adv. Biosys. 8/2019). Advanced Biosystems vol. 3, (8) 1970083-1970083.
10.1002/adbi.2019700832017
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Thompson CL, Plant JC, Wann AK,
Bishop CL, Novak P, Mitchison HM, Beales PL,
Chapple JP and
Knight MM (2017).
Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling. Eur Cell Mater vol. 34, 128-141.
10.22203/eCM.v034a09![](/publications/bullet24.png)
Nijhuis A, Thompson H, Adam J, Parker A, Gammon L, Lewis A, Bundy JG, Tomoyoshi S, Jalaly A, Propper D, Jeffery R, Suraweera N, McDonald S, THAHA MA, Feakins R, Lowe R,
Bishop CL and Silver A (2017).
Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance., Editors: Davies K and Wynshaw-Boris A.
Oxford University Press (Oup) Human Molecular Genetics 10.1093/hmg/ddx059![](/publications/bullet24.png)
Nijhuis A, Curciarello R, Mehta S, Feakins R,
Bishop CL, Lindsay JO and Silver A (2017).
MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8. Cell Tissue Res 10.1007/s00441-017-2576-12016
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Clarke RW, Novak P, Zhukov A, Tyler EJ, Cano-Jaimez M, Drews A, Richards O, Volynski K,
Bishop C and Klenerman D (2016).
Low Stress Ion Conductance Microscopy of Sub-Cellular Stiffness. Royal Society of Chemistry Soft Matter vol. 12, (38) 7953-7958.
10.1039/c6sm01106c2015
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Lowe R, Overhoff MG, Ramagopalan SV, Garbe JC, Koh J, Stampfer MR, Beach DH, Rakyan VK and
Bishop CL (2015).
The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans. Springer Nature Genome Biology vol. 16, (1)
10.1186/s13059-015-0748-4![](/publications/bullet24.png)
Lewis A, Mehta S, Hanna LN, Rogalski LA, Jeffery R, Nijhuis A, Kumagai T, Biancheri P, Bundy JG,
Bishop CL, Feakins R, Di Sabatino A, Lee JC, Lindsay JO and Silver A (2015).
Low Serum Levels of MicroRNA-19 Are Associated with a Stricturing Crohn's Disease Phenotype. Oxford University Press (Oup) Inflammatory Bowel Diseases vol. 21, (8) 1926-1934.
10.1097/mib.0000000000000443![](/publications/bullet24.png)
Moore M, Philpott M and
Bishop C (2015).
52P A siRNA screen to re-activate senescence in basal-like breast cancer. Elsevier Annals of Oncology vol. 26,
10.1093/annonc/mdv117.14![](/publications/bullet24.png)
Murray A, Letourneau A, Canzonetta C, Stathaki E, Gimelli S, Sloan-Bena F, Abrehart R, Goh P, Lim S, Baldo C, Dagna-Bricarelli F, Hannan S, Mortensen M, Ballard D, Syndercombe Court D, Fusaki N, Hasegawa M, Smart TG,
Bishop C, Antonarakis SE, Groet J and Nizetic D (2015).
Brief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegeneration. Wiley Online Stem Cells vol. 33, (6) 2077-2084.
10.1002/stem.19682014
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Nijhuis A, Biancheri P, Lewis A,
Bishop CL, Giuffrida P, Chan C, Feakins R, Poulsom R, Di Sabatino A, Corazza GR, MacDonald TT, Lindsay JO and Silver AR (2014).
In Crohn's disease fibrosis-reduced expression of the miR-29 family enhances collagen expression in intestinal fibroblasts. Clin Sci (Lond) vol. 127, (5) 341-350.
10.1042/CS201400482013
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Overhoff MG, Garbe JC, Koh J, Stampfer MR, Beach DH and
Bishop CL (2013).
Cellular senescence mediated by p16INK4A-coupled miRNA pathways. Nucleic Acids Research vol. 42, (3) 1606-1618.
10.1093/nar/gkt10962011
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Liu L, Oliveira NMM, Cheney KM, Pade C, Dreja H, Bergin A-MH, Borgdorff V, Beach DH,
Bishop CL, Dittmar MT and McKnight A (2011).
A whole genome screen for HIV restriction factors. Retrovirology vol. 8,
10.1186/1742-4690-8-942010
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Borgdorff V, Lleonart ME,
Bishop CL, Fessart D, Bergin AH, Overhoff MG and Beach DH (2010).
Multiple microRNAs rescue from Ras-induced senescence by inhibiting p21(Waf1/Cip1). Oncogene vol. 29, (15) 2262-2271.
10.1038/onc.2009.497
Bishop CL, Bergin A-M, Fessart D, Borgdorff V, Hatzimasoura E, Garbe JC, Stampfer MR, Koh J and Beach DH (2010).
Primary cilium dependent and independent Hedgehog signaling inhibits p16INK4A. Mol Cell vol. 40, (4) 533-547.
10.1016/j.molcel.2010.10.0272007
Bishop CL, Ulas S, Baena-Gonzalez E, Aro EM, Purton S, Nugent JHA and Maenpaa P (2007).
The PsbZ subunit of photosystem II in Synechocystis sp PCC 6803 modulates electron flow through the photosynthetic electron transfer chain. Photosynth Res vol. 93, (1-3) 139-147.
10.1007/s11120-007-9182-02006
Bishop CL, Ramalho M, Nadkarni N, Kong WM, Higgins CF and Krauzewicz N (2006).
Role for centromeric heterochromatin and PML nuclear bodies in the cellular response to foreign DNA (vol 26, pg 2583, 2006). Mol Cell Biol vol. 26, (10) 3997-3997.
10.1128/MCB.26.10.3997.2006
Bishop CL, Ramalho M, Nadkarni N, May Kong W, Higgins CF and Krauzewicz N (2006).
Role for centromeric heterochromatin and PML nuclear bodies in the cellular response to foreign DNA. Mol Cell Biol vol. 26, (7) 2583-2594.
10.1128/MCB.26.7.2583-2594.20062003
Bishop CL, Purton S and Nugent JHA (2003).
Molecular analysis of the Chlamydomonas nuclear gene encoding PsbW and demonstration that PsbW is a subunit of photosystem II, but not photosystem I. Plant Mol Biol vol. 52, (2) 285-289.
10.1023/a:1023963113290