Prof Cleo Bishop
Professor of Senescence
Blizard Institute
Queen Mary University of London
Queen Mary University of London
Research
Breast Cancer, Kidney, Skin, Senescence, Ageing, p16
Interests
Cleo’s is the Director of the QMUL Phenotypic Screening Facility, with >18 years experience in compound/genetic high-throughput screening using 2D/3D in vitro models.Her research seeks to illuminate senescence mechanisms, understand how cells age, explore the interplay between healthy ageing and cellular rejuvenation, and target senescence for ageing and cancer therapy.
Ageing team: understand the fundamental mechanisms that senescence heterogeneity; uncover novel routes to cellular rejuvenation; explore how senescence underpins ageing phenotypes; and discover novel senostatics and senolytics for healthy ageing.
Cancer team: how cells sense early carcinogenic events; find mechanisms to selectively trigger senescence in breast cancer; identify new genetic targets for pro-senescence therapy; and discover novel senostatic and senolytic approaches for cancer therapy.
Publications
2025

Wallis R, Hughes BK, Moore M, O’Sullivan EA, McIlvenna LC, Gammon L, Hope A, Bellany F et al.
In Cold Spring Harbor Laboratory
12-06-2025

Hughes BK, Davis A, Milligan D, Wallis R, Mossa F, Philpott MP, Wainwright LJ, Gunn DA et al.
Genome Medicine, Springer Science and Business Media Llc vol. 17 (1)
14-01-2025
2024

O’Sullivan EA, Wallis R, Mossa F, Bishop CL
Npj Aging, Springer Science and Business Media Llc vol. 10 (1)
14-09-2024

Duran I, Bishop CL, Gil J, Wallis R
Nature Aging, Springer Science and Business Media Llc vol. 4 (9), 1167-1170.
26-08-2024

Ogrodnik M, Carlos Acosta J, Adams PD, d’Adda di Fagagna F, Baker DJ, Bishop CL, Chandra T, Collado M et al.
Cell, Elsevier Bv vol. 187 (16), 4150-4175.
01-08-2024

Lujan C, Tyler EJ, Ecker S, Webster AP, Stead ER, Martinez-Miguel VE, Milligan D, Garbe JC et al.
Genome Medicine, Springer Science and Business Media Llc vol. 16 (1)
02-07-2024

Rolas L, Stein M, Barkaway A, Reglero-Real N, Sciacca E, Yaseen M, Wang H, Vazquez-Martinez L et al.
Embo Reports, Springer Nature vol. 25 (9), 3842-3869.
25-06-2024

Lowe R, Overhoff MG, Ramagopalan SV, Garbe JC, Koh J, Stampfer MR, Beach DH, Rakyan VK et al.
Genome Biology, Springer Science and Business Media Llc vol. 25 (1)
10-06-2024
2023

Bishop C, Hughes B, Davis A, Milligan D, Wallis R, Philpott M, Wainwright L, Gunn D
In Research Square Platform Llc
17-11-2023

Hughes BK, Davis A, Milligan D, Wallis R, Philpott MP, Wainwright LJ, Gunn DA, Bishop CL
In Cold Spring Harbor Laboratory
23-10-2023

Wallis R, Bishop CL
Cell Metabolism, Elsevier Bv vol. 35 (10), 1675-1676.
01-10-2023

Gorkic M, Messenger D, Wainwright L, Connelly J, Bishop CL
British Journal of Dermatology, Oxford University Press (Oup) vol. 189 (1), e27-e27.
07-07-2023

Gorkic M, Messenger D, Wainwright L, Connelly J, Bishop C
Journal of Investigative Dermatology, Elsevier Bv vol. 143 (5), S249-S249.
01-05-2023

Hughes BK, Wallis R, Bishop CL
Cell and Tissue Research, Springer Science and Business Media Llc vol. 394 (1), 1-16.
05-04-2023

Gorkic M, Messenger D, Wainwright L, Connelly J, Bishop C
01-01-2023
2022

Hughes BK, Bishop CL
Biomedicines, Mdpi Ag vol. 10 (12), 3111-3111.
02-12-2022

Wallis R, Milligan D, Hughes B, Mizen H, López-Domínguez JA, Eduputa U, Tyler EJ, Serrano M et al.
Aging, Impact Journals, Llc vol. 14 (10), 4220-4246.
16-05-2022
2021

Palmer A, Epton S, Crawley E, Straface M, Gammon L, Edgar MM, Xu Y, Elahi S et al.
Frontiers in Neuroscience, Frontiers Media Sa vol. 15
07-10-2021

Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen-Woods C, Reglero-Real N, Stein M et al.
Immunity, Elsevier vol. 54 (7), 1494-1510.e7.
24-05-2021

Tyler EJ, Gutierrez del Arroyo A, Hughes BK, Wallis R, Garbe JC, Stampfer MR, Koh J, Lowe R et al.
Aging Cell, Wiley vol. 20 (3)
06-02-2021

Wallis R, Josipovic N, Mizen H, Robles‐Tenorio A, Tyler EJ, Papantonis A, Bishop CL
Journal of Extracellular Vesicles, Wiley vol. 10 (4)
01-02-2021
2020

Tyler EJ, del Arroyo AG, Wallis R, Hughes B, Garbe JC, Stampfer MR, Koh J, Lowe R et al.
In Cold Spring Harbor Laboratory
01-10-2020

Milligan DA, Tyler EJ, Bishop CL
Mechanisms of Ageing and Development, Elsevier Bv vol. 190, 111261-111261.
01-09-2020

Wallis R, Mizen H, Bishop CL
Mechanisms of Ageing and Development, Elsevier Bv vol. 189, 111263-111263.
01-07-2020

Avelar RA, Ortega JG, Tacutu R, Tyler EJ, Bennett D, Binetti P, Budovsky A, Chatsirisupachai K et al.
Genome Biology, Springer Science and Business Media Llc vol. 21 (1)
07-04-2020
2019

Lujan C, Tyler EJ, Ecker S, Webster AP, Stead ER, Martinez Miguel VE, Milligan D, Garbe JC et al.
In Cold Spring Harbor Laboratory
13-10-2019

Gorgoulis V, Adams PD, Alimonti A, Bennett DC, Bischof O, Bishop C, Campisi J, Collado M et al.
Cell, Elsevier Bv vol. 179 (4), 813-827.
01-10-2019

Avelar RA, Ortega JG, Tacutu R, Tyler E, Bennett D, Binetti P, Budovsky A, Chatsirisupachai K et al.
In Cold Spring Harbor Laboratory
23-08-2019

Almeida FV, Gammon L, Laly AC, Pundel OJ, Bishop CL, Connelly JT
Advanced Biosystems, Wiley vol. 3 (8)
01-08-2019

Almeida FV, Gammon L, Laly AC, Pundel OJ, Bishop CL, Connelly JT
Advanced Biosystems, Wiley, 1900011-1900011.
13-06-2019

Lewis A, Nijhuis A, Berti G, Bishop CL, Feakins R, Lindsay JO, Silver A
25-01-2019
2018

Moore M, Gammon L, Dreger S, Koh J, Garbe JC, Stampfer MR, Philpott M, Jones L et al.
In Cold Spring Harbor Laboratory
14-11-2018

Bolland H, McIntyre A, Shams-Nateri A, Bishop C, Silver A
01-01-2018
2017

Milligan D, Newman J, Caley M, Wainwright L, Jenkins G, Philpott M, Bishop C
01-10-2017

Thompson CL, Plant JCT, Wann AKT, Bishop CL, Novak P, Mitchison HM, Beales PL, Chapple JP et al.
European Cells and Materials, Forum Multimedia Publishing Llc vol. 34, 128-141.
20-09-2017

Nijhuis A, Thompson H, Adam J, Parker A, Gammon L, Lewis A, Bundy JG, Soga T et al.
Human Molecular Genetics, Oxford University Press (Oup) vol. 26 (8), 1552-1564.
16-02-2017

Nijhuis A, Curciarello R, Mehta S, Feakins R, Bishop CL, Lindsay JO, Silver A
Cell and Tissue Research, Springer Science and Business Media Llc vol. 368 (2), 325-335.
11-02-2017
2016

Clarke RW, Novak P, Zhukov A, Tyler EJ, Cano-Jaimez M, Drews A, Richards O, Volynski K et al.
Soft Matter, Royal Society of Chemistry (Rsc) vol. 12 (38), 7953-7958.
01-01-2016
2015

Lowe R, Overhoff MG, Ramagopalan SV, Garbe JC, Koh J, Stampfer MR, Beach DH, Rakyan VK et al.
Genome Biology, Springer Science and Business Media Llc vol. 16 (1)
17-09-2015

Lewis A, Mehta S, Hanna LN, Rogalski LA, Jeffery R, Nijhuis A, Kumagai T, Biancheri P et al.
Inflammatory Bowel Diseases, Oxford University Press (Oup) vol. 21 (8), 1926-1934.
01-08-2015

Murray A, Letourneau A, Canzonetta C, Stathaki E, Gimelli S, Sloan-Bena F, Abrehart R, Goh P et al.
Stem Cells, Oxford University Press (Oup) vol. 33 (6), 2077-2084.
21-05-2015

Moore M, Philpott M, Bishop C
Annals of Oncology, Elsevier Bv vol. 26, iii15-iii15.
01-05-2015
2014

Nijhuis A, Biancheri P, Lewis A, Bishop CL, Giuffrida P, Chan C, Feakins R, Poulsom R et al.
Clinical Science, Portland Press Ltd. vol. 127 (5), 341-350.
15-05-2014
2013

Overhoff MG, Garbe JC, Koh J, Stampfer MR, Beach DH, Bishop CL
Nucleic Acids Research, Oxford University Press (Oup) vol. 42 (3), 1606-1618.
09-11-2013
2011

Liu L, Oliveira NMM, Cheney KM, Pade C, Dreja H, Bergin A-MH, Borgdorff V, Beach DH et al.
Retrovirology, Springer Science and Business Media Llc vol. 8 (1)
14-11-2011
2010

Bishop CL, Bergin AMH, Fessart D, Borgdorff V, Hatzimasoura E, Garbe JC, Stampfer MR, Koh J et al.
Mol Cell vol. 40 (4), 533-547.
24-11-2010

Borgdorff V, Lleonart ME, Bishop CL, Fessart D, Bergin AH, Overhoff MG, Beach DH
Oncogene vol. 29 (15), 2262-2271.
01-04-2010
2007

Bishop CL, Ulas S, Baena-Gonzalez E, Aro E-M, Purton S, Nugent JHA, Mäenpää P
Photosynthesis Research, Springer Science and Business Media Llc vol. 93 (1-3), 139-147.
22-05-2007
2006

Molecular and Cellular Biology, Informa Uk Limited vol. 26 (10), 3997-3997.
01-05-2006

Bishop CL, Ramalho M, Nadkarni N, Kong WM, Higgins CF, Krauzewicz N
Mol Cell Biol vol. 26 (7), 2583-2594.
01-04-2006
2004

Ramalho M, Bishop C, Higgins CF, Krauzewicz J
01-01-2004
2003

Bishop CL, Purton S, Nugent JHA
Plant Molecular Biology, Springer Science and Business Media Llc vol. 52 (2), 285-289.
01-05-2003

Ramalho M, Bishop CL, Higgins CF, Krauzewicz N
01-01-2003

Bishop CL, Ramalho M, McBride AA, Higgins CF, Krauzewicz N
01-01-2003
Grants


Cleo Bishop and Prabhakar Rajan
£73,420 Barts and the London Charity
18-06-2025 - 31-03-2026

Martin Knight and Cleo Bishop
£39,986 Kidney Research UK
Grant Summary
01-12-2023 - 30-11-2025

Martin Knight, Hazel Screen, Wen Wang, Clare Thompson and Cleo Bishop
£260,676 EPSRC - EU Scheme
Grant Summary
01-12-2023 - 30-11-2027

John Connelly and Cleo Bishop
£554,319 BBSRC Biotechnology and Biological Sciences Research Council
15-05-2023 - 14-05-2026

Cleo Bishop
£340,339 Wellcome Trust
01-01-2022 - 31-12-2026

Cleo Bishop and John Connelly
£118,835 BBSRC Biotechnology and Biological Sciences Research Council
01-10-2021 - 30-09-2025

Cleo Bishop and John Connelly
£76,000 Unilever UK Ltd
01-10-2021 - 30-09-2025

Cleo Bishop and Michael Philpott
£114,126 BBSRC Biotechnology and Biological Sciences Research Council
01-10-2020 - 30-09-2024

Cleo Bishop and Michael Philpott
£82,000 Unilever UK Ltd
01-10-2020 - 30-09-2024

Cleo Bishop, Oliver Pearce and John Connelly
£242,221 Barts and the London Charity
01-07-2020 - 31-05-2024

John Connelly and Cleo Bishop
£134,519 DMT Dunhill Medical Trust, The
15-04-2019 - 15-06-2021

Cleo Bishop
£178,534 BBSRC Biotechnology and Biological Sciences Research Council
19-07-2017 - 31-12-2019

Cleo Bishop
£219,622 Unilever UK Ltd
01-01-2017 - 31-12-2019

Cleo Bishop
£307,272 Barts and the London Charity
01-11-2016 - 31-10-2019

Cleo Bishop
£103,042 BBSRC Biotechnology and Biological Sciences Research Council
01-10-2015 - 30-09-2019

Cleo Bishop
£68,000 Unilever UK Ltd
01-10-2015 - 29-02-2020