Prof Amrita Ahluwalia

Amrita Ahluwalia

Dean For Research Faculty of Medicine and Dentistry

William Harvey Research Institute (WHRI)
QMUL

Research

Sex differences, Nitrite/Nitrate/Nitric oxide, Xanthine oxidoreductase, inflammation, cardiovascular

Cardiovascular Models

Interests

Sex differences in drug action related to treatment of cardiovascular disease is neglected, however, most drugs removed for use by the FDA relate to adverse effects in women. I am interested in exploring sex differences using in vitro models. Separately the enzyme xanthine oxidoreductase has been implicated in cardiovascular disease development. We have developed small molecules that target this enzyme and identified rare mutations that are linked with disease. Exploring drug action in genetic models in vitro is of interest.

Publications

Publications of specific relevance to Predictive in vitro Models

2023

Sienel RI, Mamrak U, Biller J, Roth S, Zellner A, Parakaw T, Khambata RS, Liesz A, Haffner C, Ahluwalia A, Seker BF and Plesnila N (2023). Inhaled nitric oxide suppresses neuroinflammation in experimental ischemic stroke. Springer Nature  Journal of Neuroinflammation  vol. 20, (1) 10.1186/s12974-023-02988-3
Corder R, Khan NQ, Lilley S, Fox R, Tyler J, Angbohang A, Caton PW, Mullen W, Filomena F, Ahluwalia A, Crozier A and Malkinson J (2023). Characterisation of pomegranate juice polyphenols identifies oenothein B as an endothelium-dependent vasodilator and regulator of endothelial function that enhances actions of oligomeric procyanidins. Oxford University Press (Oup)  European Heart Journal  vol. 44, (Supplement_2) 10.1093/eurheartj/ehad655.3128
Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod K, Borghi C and Ahluwalia A (2023). Corrigendum to “Natural mutations of human XDH promote the nitrite (NO2 −)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?” [Redox Biol. 4 (67) (2023) 102864]. Elsevier  Redox Biology  vol. 67, 10.1016/j.redox.2023.102925
Jones DA, Beirne A-M, Kelham M, Rathod KS, Andiapen M, Wynne L, Godec T, Forooghi N, Ramaseshan R, Moon JC, Davies C, Bourantas CV, Baumbach A, Manisty C, Wragg A, Ahluwalia A, Pugliese F, Mathur A and Committees and Investigators FTB-CT (2023). Computed Tomography Cardiac Angiography Before Invasive Coronary Angiography in Patients With Previous Bypass Surgery: The BYPASS-CTCA Trial. Wolters Kluwer  Circulation  vol. 148, (18) 1371-1380. 10.1161/circulationaha.123.064465
Shabbir A, Chhetri I, Khambata RS, Parakaw T, Lau C, Aubdool MABN, Massimo G, Dyson N, Kapil V, Godec T, Apea V, Flint J, Orkin C, Rathod KS and Ahluwalia A (2023). A double-blind, randomised, placebo-controlled parallel study to investigate the effect of sex and dietary nitrate on COVID-19 vaccine-induced vascular dysfunction in healthy men and women: protocol of the DiNOVasc-COVID-19 study. Springer Nature  Trials  vol. 24, (1) 10.1186/s13063-023-07616-2
Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod KS, Borghi C and Ahluwalia A (2023). Natural mutations of human XDH promote the nitrite (NO2 −)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health? Elsevier  Redox Biology  vol. 67, 10.1016/j.redox.2023.102864
Bosseboeuf E, Chikh A, Chaker AB, Mitchell TP, Vignaraja D, Rajendrakumar R, Khambata RS, Nightingale TD, Mason JC, Randi AM, Ahluwalia A and Raimondi C (2023). Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow. American Association For The Advancement of Science (Aaas)  Science Signaling  vol. 16, (786) 10.1126/scisignal.abo4863
Panettieri RA, Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y, Patel HH, Sobey CG, Stefanska B, Stephens G, Teixeira M, Vergnolle N, Ferdinandy P and Ahluwalia A (2023). BJP recommendations for publishing research on tobacco smoke and environmental tobacco smoke exposure. Wiley  British Journal of Pharmacology  vol. 180, (12) 1537-1541. 10.1111/bph.16089
Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y, Panettieri RA, Patel HH, Sobey CG, Stefanska B, Stephens G, Teixeira M, Vergnolle N, Ferdinandy P and Ahluwalia A (2023). Considering and reporting sex as an experimental variable II: An update on progress in the British Journal of Pharmacology. Wiley  British Journal of Pharmacology  vol. 180, (9) 1191-1196. 10.1111/bph.16049
Hikin LJ, Ho J, Morley SR, Ahluwalia A and Smith PR (2023). Sodium nitrite poisoning: A series of 20 fatalities in which post-mortem blood nitrite and nitrate concentrations are reported. Elsevier  Forensic Science International  vol. 345, 10.1016/j.forsciint.2023.111610
Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC, Bansal J, Pitrola K, Shaw C, D'Acquisto F, Colas RA, Marelli-Berg F, Dalli J and Ahluwalia A (2023). Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans. American Society For Clinical Investigation  Journal of Clinical Investigation  vol. 133, (2) 10.1172/jci168068

2022

Fernandes D, Khambata RS, Massimo G, Ruivo E, Gee LC, Foster J, Goddard A, Curtis M, Barnes MR, Wade WG, Godec T, Orlandi M, D'Aiuto F and Ahluwalia A (2022). Local delivery of nitric oxide prevents endothelial dysfunction in periodontitis. Elsevier  Pharmacological Research  vol. 188, 10.1016/j.phrs.2022.106616
Ahluwalia A, Hoa N, Moreira D, Aziz D, Singh K, Patel KN and Levin ER (2022). Membrane Estrogen Receptor β Is Sufficient to Mitigate Cardiac Cell Pathology. Endocrinology  vol. 164, (2) 10.1210/endocr/bqac200
Ingrande J, Patel HH, Kendall D, Stefanska B, Alexander S, Bakhle M, Cirino G, Docherty JR, George CH, Insel PA, Ji Y, King BF, Lilley E, Panettieri RA, Ramage AG, Sobey CG, Stanford SC, Stephens G, Teixeira M, Vergnolle N and Ahluwalia A (2022). Guidance for the use and reporting of anaesthetic agents in BJP manuscripts involving work with animals. Wiley  British Journal of Pharmacology  vol. 180, (3) 255-263. 10.1111/bph.15992
Hikin L, Ahluwalia A, Morley S and Smith P (2022). Sodium nitrite poisoning; A case series of 15 fatalities. Elsevier  Toxicologie Analytique Et Clinique  vol. 34, (3) s48-s49. 10.1016/j.toxac.2022.06.056
Curtis MJ, Alexander SPH, Cirino G, George CH, Kendall DA, Insel PA, Izzo AA, Ji Y, Panettieri RA, Patel HH, Sobey CG, Stanford SC, Stanley P, Stefanska B, Stephens GJ, Teixeira MM, Vergnolle N and Ahluwalia A (2022). Planning experiments: Updated guidance on experimental design and analysis and their reporting III. Wiley  British Journal of Pharmacology  vol. 179, (15) 3907-3913. 10.1111/bph.15868
Spitschan M, Santhi N, Ahluwalia A, Fischer D, Hunt L, Karp NA, Lévi F, Pineda-Torra I, Vidafar P and White R (2022). Sex differences and sex bias in human circadian and sleep physiology research. Elife  Elife  vol. 11, 10.7554/elife.65419
Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Moreira SAM, Rathod K, Chen J, Bubb K, Colas R, Khambata RS, Dalli J and Ahluwalia A (2022). 20‐hydroxyeicosatetraenoic acid (20‐HETE) is a pivotal endogenous ligand for TRPV1‐mediated neurogenic inflammation in the skin. Wiley  British Journal of Pharmacology  vol. 179, (7) 1450-1469. 10.1111/bph.15726
Tarnawski AS and Ahluwalia A (2022). Endothelial cells and blood vessels are major targets for COVID-19-induced tissue injury and spreading to various organs. World J Gastroenterol  vol. 28, (3) 275-289. 10.3748/wjg.v28.i3.275
Rizk JG, Wenziger C, Tran D, Hashemi L, Moradi H, Streja E and Ahluwalia A (2022). Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Use Associated with Reduced Mortality and Other Disease Outcomes in US Veterans with COVID-19. Drugs  vol. 82, (1) 43-54. 10.1007/s40265-021-01639-2

2021

Ahluwalia A, Patel K, Hoa N, Brzozowska I, Jones MK and Tarnawski AS (2021). Melatonin ameliorates aging-related impaired angiogenesis in gastric endothelial cells via local actions on mitochondria and VEGF-survivin signaling. Am J Physiol Gastrointest Liver Physiol  vol. 321, (6) G682-G689. 10.1152/ajpgi.00101.2021
Rathod KS, Jones DA, Jain AK, Lim P, MacCarthy PA, Rakhit R, Lockie T, Kalra S, Dalby MC, Malik IS, Whitbread M, Firoozi S, Bogle R, Redwood S, Cooper J, Gupta A, Lansky A, Wragg A, Mathur A and Ahluwalia A (2021). The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction. Am J Cardiovasc Dis  vol. 11, (5) 659-678.
Maffia P, Antoniades C, Ahluwalia A and Cirino G (2021). Molecular imaging—The first visual themed issue published in the British Journal of Pharmacology. Wiley  British Journal of Pharmacology  vol. 178, (21) 4213-4215. 10.1111/bph.15632
Shabbir A, Lau C, Rathod KS, Chhetri I, Haque A, Godec T, Khambata RS, Kapil V and Ahluwalia A (2021). Inorganic nitrate attenuates the systemic inflammatory response in typhoid vaccine-induced endothelial dysfunction in healthy volunteers. Oxford University Press (Oup)  European Heart Journal  vol. 42, (Supplement_1) 10.1093/eurheartj/ehab724.3009
Lau C, Shabbir A, Rathod KS, Chhetri I, Ono M, Hamers AJP, Amarin JJ, Ibrahim A, Nuredini G, Godec T, Kapil V and Ahluwalia A (2021). Inorganic nitrate attenuates endothelial dysfunction consequent to systemic inflammation. Oxford University Press (Oup)  European Heart Journal  vol. 42, (Supplement_1) 10.1093/eurheartj/ehab724.3008
Primus C, Masucci M, Whitear C, Moreira SAM, Kumar NA, Chhetri I, Rathod KS, Khambata R, Kapil V and Ahluwalia A (2021). A pro-resolving phenotype underpins the anti-inflammatory effects of inorganic nitrate. Oxford University Press (Oup)  European Heart Journal  vol. 42, (Supplement_1) 10.1093/eurheartj/ehab724.3352
Gee LC, Massimo G, Lau C, Primus C, Fernandes D, Chen J, Rathod KS, Hamers AJP, Filomena F, Nuredini G, Ibrahim AS, Khambata RS, Gupta AK, Moon JC, Kapil V and Ahluwalia A (2021). Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide. Wiley  British Journal of Pharmacology  vol. 179, (20) 4757-4777. 10.1111/bph.15636
Beirne A-M, Rathod KS, Castle E, Andiapen M, Richards A, Bellin A, Hammond V, Godec T, Moon JC, Davies C, Bourantas CV, Wragg A, Ahluwalia A, Pugliese F, Mathur A and Jones DA (2021). The BYPASS-CTCA Study: the value of Computed Tomography Cardiac Angiography (CTCA) in improving patient-related outcomes in patients with previous bypass operation undergoing invasive coronary angiography: Study Protocol of a Randomised Controlled Trial. Ame Publishing Company  Annals of Translational Medicine  10.21037/atm-21-1455
Wang J, Mei F, Bai L, Zhou S, Liu D, Yao L, Ahluwalia A, Ghiladi RA, Su L, Shu T, Gong M, Wang X, Zhu L, Cai K and Zhang X (2021). Serum nitrite and nitrate: A potential biomarker for post-covid-19 complications? Elsevier  Free Radical Biology and Medicine  vol. 175, 216-225. 10.1016/j.freeradbiomed.2021.08.237
Tarnawski AS and Ahluwalia A (2021). The Critical Role of Growth Factors in Gastric Ulcer Healing: The Cellular and Molecular Mechanisms and Potential Clinical Implications. Cells  vol. 10, (8) 10.3390/cells10081964
George CH, Alexander SPH, Cirino G, Insel PA, Izzo AA, Ji Y, Kendall DA, Panettieri RA, Patel HH, Sobey CG, Stanford SC, Stefanska B, Stephens G, Teixeira M and Ahluwalia A (2021). Editorial policy regarding the citation of preprints in the British Journal of Pharmacology (BJP). Wiley  British Journal of Pharmacology  vol. 178, (18) 3605-3610. 10.1111/bph.15589
Beirne A-M, Mitchelmore O, Palma S, Andiapen M, Rathod KS, Hammond V, Bellin A, Cooper J, Wright P, Antoniou S, Yaqoob MM, Naci H, Mathur A, Ahluwalia A and Jones DA (2021). NITRATE-CIN Study: Protocol of a Randomized (1:1) Single-Center, UK, Double-Blind Placebo-Controlled Trial Testing the Effect of Inorganic Nitrate on Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography for Acute Coronary Syndromes. Sage Publications  Journal of Cardiovascular Pharmacology and Therapeutics  vol. 26, (4) 303-309. 10.1177/1074248421000520

2020

Kelham M, Choudry FA, Hamshere S, Beirne A-M, Rathod KS, Baumbach A, Ahluwalia A, Mathur A and Jones DA (2020). Therapeutic Implications of COVID-19 for the Interventional Cardiologist. Sage Publications  Journal of Cardiovascular Pharmacology and Therapeutics  vol. 26, (3) 203-216. 10.1177/1074248420982736
Shabbir A and Ahluwalia A (2020). Second wave and second opportunity: capitalizing on cardiovascular research activity during the COVID-19 pandemic. Oxford University Press (Oup)  European Heart Journal - Quality of Care and Clinical Outcomes  vol. 7, (3) 321-322. 10.1093/ehjqcco/qcaa087
Ahluwalia A, Hoa N, Ge L, Blumberg B and Levin ER (2020). Mechanisms by Which Membrane and Nuclear ER Alpha Inhibit Adipogenesis in Cells Isolated From Female Mice. Endocrinology  vol. 161, (11) 10.1210/endocr/bqaa175
Shabbir A, Rathod KS, Khambata RS and Ahluwalia A (2020). Sex Differences in the Inflammatory Response: Pharmacological Opportunities for Therapeutics for Coronary Artery Disease. Annual Reviews  The Annual Review of Pharmacology and Toxicology  vol. 61, (1) 1-27. 10.1146/annurev-pharmtox-010919-023229
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2020). The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research. Springer Nature  Bmc Veterinary Research  vol. 16, (1) 10.1186/s12917-020-02451-y
Lilley E, Stanford SC, Kendall DE, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA, Izzo AA, Ji Y, Panettieri RA, Sobey CG, Stefanska B, Stephens G, Teixeira M and Ahluwalia A (2020). ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020. Wiley  British Journal of Pharmacology  vol. 177, (16) 3611-3616. 10.1111/bph.15178
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2020). The ARRIVE guidelines 2.0: updated guidelines for reporting animal research. Wiley  The Journal of Physiology  vol. 598, (18) 3793-3801. 10.1113/jp280389
du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2020). Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0. Public Library of Science (Plos)  Plos Biology  vol. 18, (7) 10.1371/journal.pbio.3000411
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2020). The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research*. Sage Publications  Cerebrovascular and Brain Metabolism Reviews  vol. 40, (9) 1769-1777. 10.1177/0271678x20943823
Kapil V, Khambata RS, Jones DA, Rathod K, Primus C, Massimo G, Fukuto JM and Ahluwalia A (2020). The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway. Pharmacological Reviews  vol. 72, (3) 692-766. 10.1124/pr.120.019240
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Wuerbel H (2020). The ARRIVE guidelines 2.0: updated guidelines for reporting animal research. Portico  Bmj Open Science  vol. 4, (1) 10.1136/bmjos-2020-100115
Cirino G and Ahluwalia A (2020). The many mechanisms of action of Chloroquine: to use or not to use (in COVID‐19) that is the question. Wiley  British Journal of Pharmacology  vol. 177, (15) 3361-3362. 10.1111/bph.15177
Izzo AA, Teixeira M, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA, Ji Y, Kendall DA, Panettieri RA, Sobey CG, Stanford SC, Stefanska B, Stephens G and Ahluwalia A (2020). A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: Reproducibility of natural product research. Wiley  British Journal of Pharmacology  vol. 177, (10) 2169-2178. 10.1111/bph.15054
Lau CWZ, Hamers AJP, Rathod KS, Shabbir A, Cooper J, Primus CP, Davies C, Mathur A, Moon JC, Kapil V and Ahluwalia A (2020). Randomised, double-blind, placebo-controlled clinical trial investigating the effects of inorganic nitrate in hypertension-induced target organ damage: Protocol of the NITRATE-TOD study in the UK. Bmj Journals  Bmj Open  vol. 10, (1) 10.1136/bmjopen-2019-034399

2019

Dreyer G, Kieswich J, Harwood S, Ahluwalia A and Yaqoob MM (2019). Ergocalciferol improves endothelial vasodilatory and vasoconstrictor function in an in vivo model of mild uraemia. Portland Press  Bioscience Reports  vol. 39, (12) 10.1042/bsr20190711
George CH, Alexander SPH, Cirino G, Docherty JR, Hoyer D, Insel PA, Izzo AA, Ji Y, Panettieri RA, Sobey CG, Stanford SC, Stefanska B, Stephens G, Teixeira M and Ahluwalia A (2019). The BJP expects authors to share data. Wiley  British Journal of Pharmacology  vol. 176, (24) 4595-4598. 10.1111/bph.14907
Ahluwalia A, Hoa N, Jones MK and Tarnawski AS (2019). NSAID-induced injury of gastric epithelial cells is reversible: roles of mitochondria, AMP kinase, NGF, and PGE2. Am J Physiol Gastrointest Liver Physiol  vol. 317, (6) G862-G871. 10.1152/ajpgi.00192.2019
Ingram JR and Ahluwalia A (2019). The pharmacology of itch. Wiley  British Journal of Pharmacology  vol. 176, (23) 4419-4420. 10.1111/bph.14865
Ingram JR and Ahluwalia A (2019). The pharmacology of itch. Wiley  British Journal of Dermatology  10.1111/bjd.18525
Jones DA, Mathur A and Ahluwalia A (2019). Letter by Jones et al regarding article, “Optimized treatment of ST-elevation myocardial infarction”. American Heart Association  Circulation Research  vol. 125, (6) E29-E29. 10.1161/CIRCRESAHA.119.315692
Docherty JR, Stanford SC, Panettieri RA, Alexander SPH, Cirino G, George CH, Hoyer D, Izzo AA, Ji Y, Lilley E, Sobey CG, Stanley P, Stefanska B, Stephens G, Teixeira M and Ahluwalia A (2019). Sex: A change in our guidelines to authors to ensure that this is no longer an ignored experimental variable. Wiley  British Journal of Pharmacology  vol. 176, (21) 4081-4086. 10.1111/bph.14761
du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2019). Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019. Cold Spring Harbor Laboratory  10.1101/703355
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lidster K, MacCallum CJ, Macleod M, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2019). The ARRIVE guidelines 2019: updated guidelines for reporting animal research. Cold Spring Harbor Laboratory  10.1101/703181
Ahluwalia A, Jones MK, Hoa N and Tarnawski AS (2019). Mitochondria in gastric epithelial cells are the key targets for NSAIDs-induced injury and NGF cytoprotection. J Cell Biochem  vol. 120, (7) 11651-11659. 10.1002/jcb.28445
Jones DA, Rathod KS, Williamson A, Mand K, Harrington D, Andiapen M, van Eijl S, Westwood M, Antoniou S, Schilling RJ, Ahluwalia A and Mathur A (2019). Corrigendum to “The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction” [Int. J. Cardiol. 266 (2018) 1–6]. Elsevier  International Journal of Cardiology  vol. 292, 10.1016/j.ijcard.2019.04.076
Guzik TJ and Ahluwalia A (2019). Plan S: in Service or Disservice to Society?The controversial plan for scientific research publications to be published in compliant Open Access Journals or on compliant Open Access Platforms, is discussed. Oxford University Press (Oup)  European Heart Journal  vol. 40, (12) 949-952. 10.1093/eurheartj/ehz065
Guzik TJ and Ahluwalia A (2019). Plan S: In service or disservice to society? Wiley  British Journal of Pharmacology  vol. 176, (6) 753-756. 10.1111/bph.14590

2018

Tarnawski AS and Ahluwalia A (2018). Increased susceptibility of aging gastric mucosa to injury and delayed healing: Clinical implications. World J Gastroenterol  vol. 24, (42) 4721-4727. 10.3748/wjg.v24.i42.4721
Jones DA, Rathod KS, Williamson A, Harrington D, Andiapen M, van Eijl S, Westwood M, Antoniou S, Schilling RJ, Ahluwalia A and Mathur A (2018). The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction. Elsevier  International Journal of Cardiology  vol. 266, 1-6. 10.1016/j.ijcard.2018.01.029
Curtis MJ, Ashton JC, Moon LDF and Ahluwalia A (2018). Clarification of the basis for the selection of requirements for publication in the British Journal of Pharmacology. Wiley  British Journal of Pharmacology  vol. 175, (18) 3633-3635. 10.1111/bph.14443
AHLUWALIA A, JONES D and MATHUR A (2018). Sodium Nitrite-Mediated Cardioprotection in Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: A Cost-Effectiveness Analysis. Sage Publications  Journal of Cardiovascular Pharmacology and Therapeutics  10.1177/1074248418784940
Jones DA, Whittaker P, Rathod KS, Richards AJ, Andiapen M, Antoniou S, Mathur A and Ahluwalia A (2018). P2564Sodium nitrite-mediated cardioprotection in primary percutaneous coronary intervention for ST-elevation myocardial infarction: a cost-effectiveness analysis. Oxford University Press (Oup)  European Heart Journal  vol. 39, (suppl_1) 10.1093/eurheartj/ehy565.p2564
Kapil V, Rathod KS, Khambata RS, Bahra M, Velmurugan S, Purba A, Watson DS, Barnes MR, Wade WG and Ahluwalia A (2018). Sex differences in the nitrate-nitrite-NO• pathway: Role of oral nitrate-reducing bacteria. Elsevier  Free Radical Biology and Medicine  vol. 126, 113-121. 10.1016/j.freeradbiomed.2018.07.010
Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J, Thiemermann C and Ahluwalia A (2018). Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis. Faseb J  fj201701303-fj201701303. 10.1096/fj.201701303R
Ahluwalia A and Cirino G (2018). Launch of mini‐reviews in hot topics. Wiley  British Journal of Pharmacology  vol. 175, (13) 2537-2537. 10.1111/bph.14342
du Sert NP, Hurst V, Ahluwalia A, Alam S, Altman DG, Avey MT, Baker M, Browne W, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Howells DW, Karp NA, MacCallum CJ, Macleod M, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H and Holgate ST (2018). Revision of the ARRIVE guidelines: rationale and scope. Portico  Bmj Open Science  vol. 2, (1) 10.1136/bmjos-2018-000002
Yellon DM, He Z, Khambata R, Ahluwalia A and Davidson SM (2018). The GTN patch: a simple and effective new approach to cardioprotection? Springer Nature  Basic Research in Cardiology  vol. 113, (3) 10.1007/s00395-018-0681-2
Curtis MJ, Alexander S, Cirino G, Docherty JR, George CH, Giembycz MA, Hoyer D, Insel PA, Izzo AA, Ji Y, MacEwan DJ, Sobey CG, Stanford SC, Teixeira MM, Wonnacott S and Ahluwalia A (2018). Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers. Wiley  British Journal of Pharmacology  vol. 175, (7) 987-993. 10.1111/bph.14153
Ahluwalia A, Brzozowska IM, Hoa N, Jones MK and Tarnawski AS (2018). Melatonin signaling in mitochondria extends beyond neurons and neuroprotection: Implications for angiogenesis and cardio/gastroprotection. Proc Natl Acad Sci U S A  vol. 115, (9) E1942-E1943. 10.1073/pnas.1722131115
AHLUWALIA A (2018). Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology. Wiley  British Journal of Pharmacology  vol. 175, 407-411. 10.1111/bph.14112
Ahluwalia A, Jones MK, Hoa N, Zhu E, Brzozowski T and Tarnawski AS (2018). Reduced NGF in Gastric Endothelial Cells Is One of the Main Causes of Impaired Angiogenesis in Aging Gastric Mucosa. Cell Mol Gastroenterol Hepatol  vol. 6, (2) 199-213. 10.1016/j.jcmgh.2018.05.003
Jandhyala DM, Ahluwalia A, Schimmel JJ, Rogers AB, Leong JM and Thorpe CM (2018). Correction for Jandhyala et al., Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation. Infect Immun  vol. 86, (1) 10.1128/IAI.00753-17

2017

Osborne NJ, Ritskes-Hoitinga M, Ahluwahlia A, Alam S, Brown M, Henderson H, de Leeuw W, Marsh J, Moher D, van Oort E, Rawle F, Riederer BM, Sanchez-Morgado J, Sena ES, Struthers C, Westmore M, Avey MT, Kalman R, O’Connor A, Sargeant J, Petrie A and Smith A (2017). Letter to the editor - round table unites to tackle culture change in an effort to improve animal research reporting. Springer Nature  Bmc Veterinary Research  vol. 13, (1) 10.1186/s12917-017-1235-9
Kapil V (2017). Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017. Bmc Pharmacol Toxicol  vol. 18, (Suppl 1) 64-64. 10.1186/s40360-017-0170-5
Ahluwalia A, Jones MK, Hoa N and Tarnawski AS (2017). NGF protects endothelial cells from indomethacin-induced injury through activation of mitochondria and upregulation of IGF-1. Elsevier  Cellular Signalling  vol. 40, 22-29. 10.1016/j.cellsig.2017.08.006
Rathod KS, Hamshere S, Khambata RS, Andiapen M, Westwood M, Mathur A, Ahluwalia A and Jones DA (2017). Combined analysis of the safety of intra-coronary drug delivery during primary percutaneous coronary intervention for acute myocardial infarction: A study of three clinical trials. Sage Journals  Jrsm Cardiovasc Dis  vol. 6, 20480040177-20480040177. 10.1177/2048004017725988
George CH, Stanford SC, Alexander S, Cirino G, Docherty JR, Giembycz MA, Hoyer D, Insel PA, Izzo AA, Ji Y, MacEwan DJ, Sobey CG, Wonnacott S and Ahluwalia A (2017). Updating the guidelines for data transparency in the British Journal of Pharmacology – data sharing and the use of scatter plots instead of bar charts. Wiley  British Journal of Pharmacology  vol. 174, (17) 2801-2804. 10.1111/bph.13925
Campo G, Pavasini R, Morciano G, Lincoff MA, Gibson MC, Kitakaze M, Lonborg J, Ahluwalia A, Ishii H, Frenneaux M, Ovize M, Galvani M, Atar D, Ibanez B, Cerisano G, Biscaglia S, Neil BJ, Asakura M, Engstrom T, Jones DA, Dawson D, Ferrari R, Pinton P and Ottani F (2017). Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention. Elsevier  Data in Brief  vol. 14, 197-205. 10.1016/j.dib.2017.07.033
Yuzugulen J, Douthwaite JA, Wood EG, Villar IC, Patel NSA, Jegard J, Gaertner H, Rossitto-Borlat I, Rose K, Hartley O, Cutillas PR, Ahluwalia A and Corder R (2017). Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1. Sci Rep  vol. 7, (1) 4956-4956. 10.1038/s41598-017-05365-2
Campo G, Pavasini R, Morciano G, Lincoff AM, Gibson CM, Kitakaze M, Lonborg J, Ahluwalia A, Ishii H, Frenneaux M, Ovize M, Galvani M, Atar D, Ibanez B, Cerisano G, Biscaglia S, Neil BJ, Asakura M, Engstrom T, Jones DA, Dawson D, Ferrari R, Pinton P and Ottani F (2017). Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials. Elsevier  International Journal of Cardiology  vol. 244, 59-66. 10.1016/j.ijcard.2017.06.040
AHLUWALIA A (2017). The anti-inflammatory actions of inorganic nitrate stabilise the atherosclerotic plaque. National Academy of Sciences  Proceedings of The National Academy of Sciences of Usa  10.1073/pnas.1613063114
Jones DA, Rathod KS and Ahluwalia A (2017). Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation. Nitric Oxide: Biology and Pathobiology: Third Edition  10.1016/B978-0-12-804273-1.00015-6
Jones DA, Rathod KS and Ahluwalia A (2017). Chapter 15 Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation. Nitric Oxide  Elsevier  10.1016/b978-0-12-804273-1.00015-6

2016

Rathod KS, Jones DA, Van-Eijl TJA, Tsang H, Warren H, Hamshere SM, Kapil V, Jain AK, Deaner A, Poulter N, Caulfield MJ, Mathur A and Ahluwalia A (2016). Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study. Bmj  Bmj Open  vol. 6, (12) 10.1136/bmjopen-2016-012728
AHLUWALIA A (2016). Accelerated resolution underlies sex differences in the inflammatory response in human. American Society For Clinical Investigation  Journal of Clinical Investigation  vol. 127, (1) 169-182. 10.1172/JCI89429.
Ahluwalia A, Jones MK, Brzozowski T and Tarnawski AS (2016). Nerve growth factor is critical requirement for in vitro angiogenesis in gastric endothelial cells. American Physiological Society  Ajp Gastrointestinal and Liver Physiology  vol. 311, (5) g981-g987. 10.1152/ajpgi.00334.2016
Jones DA, Khambata RS, Andiapen M, Rathod KS, Mathur A and Ahluwalia A (2016). Intracoronary nitrite suppresses the inflammatory response following primary percutaneous coronary intervention. Bmj Publishing Group  Heart  10.1136/heartjnl-2016-309748
Hoa NT, Ge L, Martini F, Chau V, Ahluwalia A, Kruse CA and Jadus MR (2016). Temozolomide induces the expression of the glioma Big Potassium (gBK) ion channel, while inhibiting fascin-1 expression: possible targets for glioma therapy. Taylor & Francis  Expert Opinion On Therapeutic Targets  vol. 20, (10) 1155-1167. 10.1080/14728222.2016.1208172
Ahluwalia A, Gladwin M, Coleman GD, Hord N, Howard G, Kim‐Shapiro DB, Lajous M, Larsen FJ, Lefer DJ, McClure LA, Nolan BT, Pluta R, Schechter A, Wang C, Ward MH and Harman JL (2016). Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop. Wolters Kluwer  Journal of The American Heart Association  vol. 5, (7) 10.1161/jaha.116.003402
Samarasena JB, Ahluwalia A, Shinoura S, Choi KD, Lee JG, Chang KJ and Tarnawski AS (2016). In vivo imaging of porcine gastric enteric nervous system using confocal laser endomicroscopy &molecular neuronal probe. Wiley  Journal of Gastroenterology and Hepatology  vol. 31, (4) 802-807. 10.1111/jgh.13194
Ivanova E, Coroiu A, Ahluwalia A, Alexandrov E and Lafreniere KD (2016). Preliminary Findings on the Association Between Symptoms of Depression and Adherence to Antiretroviral Therapy in Individuals Born Inside Versus Outside of Canada. Wolters Kluwer  Journal of The Association of Nurses in Aids Care  vol. 27, (4) 512-523. 10.1016/j.jana.2016.02.005
Aguinaldo JP, Ahluwalia A, Hambly K, Koornstra J, Rankin B and Roesslein K (2016). Needs and Supports in Transitional Housing for People Living with HIV/AIDS in Ontario, Canada. Taylor & Francis  Journal of Social Service Research  vol. 42, (3) 352-362. 10.1080/01488376.2015.1101046
Gee LC and Ahluwalia A (2016). Dietary Nitrate Lowers Blood Pressure: Epidemiological, Pre-clinical Experimental and Clinical Trial Evidence. Springer Nature  Current Hypertension Reports  vol. 18, (2) 10.1007/s11906-015-0623-4
Rathod KS, Velmurugan S and Ahluwalia A (2016). A 'green' diet-based approach to cardiovascular health? Is inorganic nitrate the answer? Molecular Nutrition and Food Research  vol. 60, (1) 185-202. 10.1002/mnfr.201500313

2015

Velmurugan S, Gan JM, Rathod KS, Khambata RS, Ghosh SM, Hartley A, Van Eijl S, Sagi-Kiss V, Chowdhury TA, Curtis M, Kuhnle GG, Wade WG and Ahluwalia A (2015). Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study 1–3. Elsevier  American Journal of Clinical Nutrition  vol. 103, (1) 25-38. 10.3945/ajcn.115.116244
Jandhyala DM, Ahluwalia A, Schimmel JJ, Rogers AB, Leong JM and Thorpe CM (2015). Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation. American Society For Microbiology  Infection and Immunity  vol. 84, (1) 138-148. 10.1128/iai.00977-15
Rathod KS, Velmurugan S and Ahluwalia A (2015). A ‘green’ diet‐based approach to cardiovascular health? Is inorganic nitrate the answer? Wiley  Molecular Nutrition & Food Research  vol. 60, (1) 185-202. 10.1002/mnfr.201500313
Samarasena JB, Tarnawski AS, Ahluwalia A, Shinoura S, Choi KD, Lee JG and Chang KJ (2015). EUS-guided in vivo imaging of the porcine esophageal enteric nervous system by using needle-based confocal laser endomicroscopy. Elsevier  Gastrointestinal Endoscopy  vol. 82, (6) 1116-1120. 10.1016/j.gie.2015.06.048
(2015). Erratum. Wiley  British Journal of Pharmacology  vol. 172, (18) 4600-4600. 10.1111/bph.13275
Curtis MJ, Bond RA, Spina D, Ahluwalia A, Alexander SPA, Giembycz MA, Gilchrist A, Hoyer D, Insel PA, Izzo AA, Lawrence AJ, MacEwan DJ, Moon LDF, Wonnacott S, Weston AH and McGrath JC (2015). Editorial. Wiley  British Journal of Pharmacology  vol. 172, (14) 3461-3471. 10.1111/bph.12856
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A (2015). Erratum: Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex (Free Radical Biology and Medicine (2013) 65 (1521-1532)). Free Radical Biology and Medicine  vol. 84, 10.1016/j.freeradbiomed.2015.03.015
Tolstanova G, Deng X, Ahluwalia A, Paunovic B, Prysiazhniuk A, Ostapchenko L, Tarnawski A, Sandor Z and Szabo S (2015). Role of Dopamine and D2 Dopamine Receptor in the Pathogenesis of Inflammatory Bowel Disease. Springer Nature  Digestive Diseases and Sciences  vol. 60, (10) 2963-2975. 10.1007/s10620-015-3698-5
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A (2015). Erratum to “Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex” [Free Radic. Biol. Med. 65 (2013) 1521–1532]. Elsevier  Free Radical Biology and Medicine  vol. 84, 10.1016/j.freeradbiomed.2015.03.015
Khambata RS, Ghosh SM and Ahluwalia A (2015). “Repurposing” of Xanthine Oxidoreductase as a Nitrite Reductase: A New Paradigm for Therapeutic Targeting in Hypertension. Mary Ann Liebert  Antioxidants & Redox Signaling  vol. 23, (4) 340-353. 10.1089/ars.2015.6254
Lara J, Ashor AW, Oggioni C, Ahluwalia A, Mathers JC and Siervo M (2015). Effects of inorganic nitrate and beetroot supplementation on endothelial function: a systematic review and meta-analysis. Springer Nature  European Journal of Nutrition  vol. 55, (2) 451-459. 10.1007/s00394-015-0872-7
Macé V, Ahluwalia A, Coron E, Le Rhun M, Boureille A, Bossard C, Mosnier J, Matysiak‐Budnik T and Tarnawski AS (2015). Confocal laser endomicroscopy & colitis. Wiley  Journal of Gastroenterology and Hepatology  vol. 30, (S1) 85-92. 10.1111/jgh.12748
Kapil V, Khambata RS, Robertson A, Caulfield MJ and Ahluwalia A (2015). Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: A randomized, phase 2, double-blind, placebo-controlled study. Lippincott Williams and Wilkins  Hypertension  vol. 65, (2) 320-327. 10.1161/HYPERTENSIONAHA.114.04675
Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, Van Eijl S, Webb AJ, Westwood MA, Parmar MK, Mathur A and Ahluwalia A (2015). Randomized phase 2 trial of intracoronary nitrite during acute myocardial infarction. Circulation Research  vol. 116, (3) 437-447. 10.1161/CIRCRESAHA.116.305082

2014

Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, van Eijl S, Webb AJ, Westwood MA, Parmar MK, Mathur A and Ahluwalia A (2014). Randomized Phase 2 Trial of Intracoronary Nitrite During Acute Myocardial Infarction. Wolters Kluwer  Circulation Research  vol. 116, (3) 437-447. 10.1161/circresaha.116.305082
Tarnawski AS, Ahluwalia A and Jones MK (2014). Angiogenesis in gastric mucosa. Wiley  Journal of Gastroenterology and Hepatology  vol. 29, (S4) 112-123. 10.1111/jgh.12734
Kapil V, Khambata RS, Robertson A, Caulfield MJ and Ahluwalia A (2014). Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients. Wolters Kluwer  Hypertension  vol. 65, (2) 320-327. 10.1161/hypertensionaha.114.04675
Velmurugan S, Ghosh S, Khambata R, Van Eijl S, Robertson A, Chowdhury T and Ahluwalia A (2014). P200 Dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia. Elsevier  Nitric Oxide  vol. 42, 10.1016/j.niox.2014.09.141
Rathod K, Ghosh S, Khambata R and Ahluwalia A (2014). P175 Xanthine oxidoreductase in atherosclerotic mice: Determination of expression and nitrite reductase activity. Elsevier  Nitric Oxide  vol. 42, 10.1016/j.niox.2014.09.119
Jones DA, Pellaton C, Velmurugan S, Andiapen M, Antoniou S, Van Eijl S, Westwood MA, Webb AJ, Mathur A and Ahluwalia A (2014). P141 The safety and efficacy of intra-coronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): A single centre, randomised, double-blind controlled trial. Elsevier  Nitric Oxide  vol. 42, 127-128. 10.1016/j.niox.2014.09.087
Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ, Rebstock A-S, Worthington RJ, Simone MI, Mota F, Rivilla F, Vallejo S, Peiró C, Sánchez Ferrer CF, Djordjevic S, Caulfield MJ, MacAllister RJ, Selwood DL, Ahluwalia A and Hobbs AJ (2014). Endothelial C-type natriuretic peptide maintains vascular homeostasis. J Clin Invest  vol. 124, (9) 4039-4051. 10.1172/JCI74281
Ahluwalia A, Baatar D, Jones MK and Tarnawski AS (2014). Novel mechanisms and signaling pathways of esophageal ulcer healing: the role of prostaglandin EP2 receptors, cAMP, and pCREB. American Physiological Society  Ajp Gastrointestinal and Liver Physiology  vol. 307, (6) g602-g610. 10.1152/ajpgi.00177.2014
Kapil V, Weitzberg E, Lundberg JO and Ahluwalia A (2014). Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health. Nitric Oxide  vol. 38, 45-57. 10.1016/j.niox.2014.03.162
Kapil V, Weitzberg E, Lundberg JO and Ahluwalia A (2014). Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health. Nitric Oxide - Biology and Chemistry  vol. 38, (1) 45-57. 10.1016/j.niox.2014.03.162
Khomenko T, Deng X, Ahluwalia A, Tarnawski A, Patel KN, Sandor Z and Szabo S (2014). STAT3 and Importins Are Novel Mediators of Early Molecular and Cellular Responses in Experimental Duodenal Ulceration. Springer Nature  Digestive Diseases and Sciences  vol. 59, (2) 297-306. 10.1007/s10620-013-2807-6
Tarnawski AS, Ahluwalia A and Jones MK (2014). Increased susceptibility of aging gastric mucosa to injury: The mechanisms and clinical implications. Baishideng Publishing Group  World Journal of Gastroenterology  vol. 20, (16) 4467-4482. 10.3748/wjg.v20.i16.4467
Ahluwalia A, Jones MK, Matysiak-Budnik T and Tarnawski AS (2014). VEGF and colon cancer growth beyond angiogenesis: does VEGF directly mediate colon cancer growth via a non-angiogenic mechanism? Bentham Science Publishers  Current Pharmaceutical Design  vol. 20, (7) 1041-1044. 10.2174/1381612819999131218175905

2013

Ahluwalia A, Jones MK and Tarnawski AS (2013). Key role of endothelial importin-α in VEGF expression and gastric angiogenesis: novel insight into aging gastropathy. American Physiological Society  Ajp Gastrointestinal and Liver Physiology  vol. 306, (4) g338-g345. 10.1152/ajpgi.00382.2013
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A (2013). Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex. Free Radic Biol Med  vol. 65, 1521-1532. 10.1016/j.freeradbiomed.2013.06.031
Yuzugulen J, Wood EG, Villar IC, Douthwaite JA, Patel NSAI, Jegard J, Montoya A, Cutillas P, Gaertner H, Rossitto-Borlat I, Rose K, Hartley O, Ahluwalia A and Corder R (2013). Characterisation of the “Endothelin-Like Domain Peptide” (ELDP) co-synthesised with Endothelin-1 from the EDN1 gene. Elsevier  Life Sciences  vol. 93, (25-26) 10.1016/j.lfs.2013.12.037
Bubb KJ, Wen H, Panayiotou CM, Finsterbusch M, Khan FJ, Chan MV, Priestley JV, Baker MD and Ahluwalia A (2013). Activation of neuronal transient receptor potential vanilloid 1 channel underlies 20-hydroxyeicosatetraenoic acid-induced vasoactivity: role for protein kinase A. Hypertension  vol. 62, (2) 426-433. 10.1161/HYPERTENSIONAHA.111.00942
Ahluwalia A, Jones MK, Szabo S and Tarnawski AS (2013). Aberrant, ectopic expression of VEGF and VEGF receptors 1 and 2 in malignant colonic epithelial cells. Implications for these cells growth via an autocrine mechanism. Elsevier  Biochemical and Biophysical Research Communications  vol. 437, (4) 515-520. 10.1016/j.bbrc.2013.06.096
Ahluwalia A, Jones MK, Deng X, Sandor Z, Szabo S and Tarnawski AS (2013). An imbalance between VEGF and endostatin underlies impaired angiogenesis in gastric mucosa of aging rats. American Physiological Society  Ajp Gastrointestinal and Liver Physiology  vol. 305, (4) g325-g332. 10.1152/ajpgi.00127.2013
Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S, Yousuf M, Benjamin N, Webb AJ, Caulfield MJ, Hobbs AJ and Ahluwalia A (2013). Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential. Hypertension  vol. 61, (5) 1091-1102. 10.1161/HYPERTENSIONAHA.111.00933
Kapil V, Haydar SMA, Pearl V, Lundberg JO, Weitzberg E and Ahluwalia A (2013). Physiological role for nitrate-reducing oral bacteria in blood pressure control. Free Radic Biol Med  vol. 55, 93-100. 10.1016/j.freeradbiomed.2012.11.013
Ahluwalia A and Hobbs AJ (2013). Letter by Ahluwalia and Hobbs Regarding Article, Nitrate-Nitrite-Nitric Oxide Pathway in Pulmonary Arterial Hypertension Therapeutics. Circulation  vol. 127, (2) E275-E275. 10.1161/CIRCULATIONAHA.112.118356
Jones DA, Andiapen M, Van-Eijl TJA, Webb AJ, Antoniou S, Schilling RJ, Ahluwalia A and Mathur A (2013). The safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): study protocol of a randomised controlled trial. Bmj Open  vol. 3, (4) 10.1136/bmjopen-2013-002813
Rousselle A, Qadri F, Leukel L, Yilmaz R, Fontaine J-F, Sihn G, Bader M, Ahluwalia A and Duchene J (2013). CXCL5 limits macrophage foam cell formation in atherosclerosis. Journal of Clinical Investigation  vol. 123, (3) 1343-1347. 10.1172/JCI66580
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A (2013). Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex. Free Radical Biology and Medicine  vol. 65, 1521-1532. 10.1016/j.freeradbiomed.2013.06.031

2012

Chan MV, Bubb KJ, Noyce A, Villar IC, Duchene J, Hobbs AJ, Scotland RS and Ahluwalia A (2012). Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation. Br J Pharmacol  vol. 167, (4) 805-817. 10.1111/j.1476-5381.2012.02012.x
Bubb KJ, Khambata RS and Ahluwalia A (2012). Sexual dimorphism in rodent models of hypertension and atherosclerosis. Br J Pharmacol  vol. 167, (2) 298-312. 10.1111/j.1476-5381.2012.02036.x
Baliga RS, Milsom AB, Ghosh SM, Trinder SL, Macallister RJ, Ahluwalia A and Hobbs AJ (2012). Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase. Circulation  vol. 125, (23) 2922-2932. 10.1161/CIRCULATIONAHA.112.100586
Bahra M, Kapil V, Pearl V, Ghosh S and Ahluwalia A (2012). Inorganic nitrate ingestion improves vascular compliance but does not alter flow-mediated dilatation in healthy volunteers. Nitric Oxide  vol. 26, (4) 197-202. 10.1016/j.niox.2012.01.004
Wen H, Östman J, Bubb KJ, Panayiotou C, Priestley JV, Baker MD and Ahluwalia A (2012). 20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel. J Biol Chem  vol. 287, (17) 13868-13876. 10.1074/jbc.M111.334896
Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Del Carro U, Zambroni D, Brain SD, Perretti M, Ahluwalia A, Priestley JV, Chavakis T, Imhof BA, Feltri ML and Nourshargh S (2012). Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves. Faseb J  vol. 26, (3) 1064-1076. 10.1096/fj.11-196220
Yuzugulen J, Wood EG, Douthwaite JA, Villar IC, Patel NS, Jegard J, Montoya A, Cutillas P, Hartley O, Ahluwalia A and Corder R (2012). Characterization of Proendothelin-1 Derived Peptides Identifies a Co-secreted Modulator of ET-1 Vasoconstriction, and Provides Insights for Biomarker Measurements. Circulation  vol. 126, (21)
Velmurugan S, Pearl V, Ghosh SM, Davies S, Khambata RS, van Eijl S, Kapil V and Ahluwalia A (2012). Inorganic Nitrate Attenuates Platelet Reactivity in Healthy Males but not Females: Role of the Erythrocyte and Cyclic GMP. Circulation  vol. 126, (21)
Moyes AJ, Khambata RS, Ahluwalia A and Hobbs AJ (2012). Accelerated Atherogenesis and Diminished Vascular Integrity in Mice Lacking Endothelial C-Type Natriuretic Peptide. Circulation  vol. 126, (21)
Stone SM, Thorpe CM, Ahluwalia A, Rogers AB, Obata F, Vozenilek A, Kolling GL, Kane AV, Magun BE and Jandhyala DM (2012). Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib. Frontiers  Frontiers in Cellular and Infection Microbiology  vol. 2, 10.3389/fcimb.2012.00135

2011

Duchene J and Ahluwalia A (2011). Kallikrein-kinin system in inflammation. 10.1515/9783110252354
Duchene J and Ahluwalia A (2011). 16 Kallikrein-kinin system in infl ammation. Kinins  De Gruyter  10.1515/9783110252354.261
Paunovic B, Deng X, Khomenko T, Ahluwalia A, Tolstanova G, Tarnawski A, Szabo S and Sandor Z (2011). Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats. American Society For Pharmacology & Experimental Therapeutics (Aspet)  Journal of Pharmacology and Experimental Therapeutics  vol. 339, (2) 430-437. 10.1124/jpet.111.183665
Florkiewicz RZ, Ahluwalia A, Sandor Z, Szabo S and Tarnawski AS (2011). Gastric mucosal injury activates bFGF gene expression and triggers preferential translation of high molecular weight bFGF isoforms through CUG-initiated, non-canonical codons. Elsevier  Biochemical and Biophysical Research Communications  vol. 409, (3) 494-499. 10.1016/j.bbrc.2011.05.033
Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ and Ahluwalia A (2011). Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin. Arterioscler Thromb Vasc Biol  vol. 31, (5) 1075-1083. 10.1161/ATVBAHA.111.223545
Monette LE, Rourke SB, Gibson K, Bekele TM, Tucker R, Greene S, Sobota M, Koornstra J, Byers S, Marks E, Bacon J, Watson JR, Hwang SW, Ahluwalia A, Dunn JR, Guenter D, Hambly K, Bhuiyan S and Positive Spaces Healthy Places Team (2011). Inequalities in Determinants of Health Among Aboriginal and Caucasian Persons Living With HIV/AIDS in Ontario: Results From the Positive Spaces, Healthy Places Study. Springer Nature  Canadian Journal of Public Health  vol. 102, (3) 215-219. 10.1007/bf03404900
Kapil V, Benjamin N, Hobbs A and Ahluwalia A (2011). Response to Inorganic Nitrate for Blood Pressure Lowering? Hypertension  vol. 57, (2) E3-E3. 10.1161/HYPERTENSIONAHA.110.164814
Rourke SB, Sobota M, Tucker R, Bekele T, Gibson K, Greene S, Price C, Koornstra JJJ, Monette L, Byers S, Watson J, Hwang SW, Guenter D, Dunn J, Ahluwalia A, Wilson MG and Bacon J (2011). Social determinants of health associated with hepatitis C co-infection among people living with HIV: results from the Positive Spaces, Healthy Places study. Open Medicine  vol. 5, (3) e120-e131.

2010

Kapil V, Webb AJ and Ahluwalia A (2010). Inorganic nitrate and the cardiovascular system. Heart  vol. 96, (21) 1703-1709. 10.1136/hrt.2009.180372
Yamashiro K, Milsom AB, Duchene J, Panayiotou C, Urabe T, Hattori N and Ahluwalia A (2010). Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice. J Cereb Blood Flow Metab  vol. 30, (8) 1494-1503. 10.1038/jcbfm.2010.34
Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, Arghandawi S, Pearl V, Benjamin N, Loukogeorgakis S, Macallister R, Hobbs AJ, Webb AJ and Ahluwalia A (2010). Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO. Hypertension  vol. 56, (2) 274-281. 10.1161/HYPERTENSIONAHA.110.153536
Tarnawski AS, Pai R, Tanigawa T, Matysiak-Budnik T and Ahluwalia A (2010). PTEN silencing reverses aging-related impairment of angiogenesis in microvascular endothelial cells. Elsevier  Biochemical and Biophysical Research Communications  vol. 394, (2) 291-296. 10.1016/j.bbrc.2010.02.161
Milsom AB, Patel NSA, Mazzon E, Tripatara P, Storey A, Mota-Filipe H, Sepodes B, Webb AJ, Cuzzocrea S, Hobbs AJ, Thiemermann C and Ahluwalia A (2010). Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice. Nitric Oxide-Biol Ch  vol. 22, (2) 141-148. 10.1016/j.niox.2009.10.010
(2010). A Role of Matrix Metalloproteinase-8 in Atherosclerosis: Correction. Wolters Kluwer  Circulation Research  vol. 106, (1) 10.1161/res.0b013e3181cdee32
WEBB A, Webb A and Ahluwalia A (2010). Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System. Nitric Oxide Biology and Pathobiology , Editors: Ignarro LJ. Academic Press  10.1016/B978-0-12-373866-0.00017-4
Webb A and Ahluwalia A (2010). Chapter 17 Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System. Nitric Oxide  Elsevier  10.1016/b978-0-12-373866-0.00017-4
Webb AJ and Ahluwalia A (2010). Mechanisms of nitrite reduction in ischemia in the cardiovascular system. Nitric Oxide: Biology and Pathobiology , Editors: Ignarro L. Elsevier  10.1016/B978-0-12-373866-0.00017-4

2009

Lundberg JO, Gladwin MT, Ahluwalia A, Benjamin N, Bryan NS, Butler A, Cabrales P, Fago A, Feelisch M, Ford PC, Freeman BA, Frenneaux M, Friedman J, Kelm M, Kevil CG, Kim-Shapiro DB, Kozlov AV, Lancaster JR, Lefer DJ, McColl K, McCurry K, Patel RP, Petersson J, Rassaf T, Reutov VP, Richter-Addo GB, Schechter A, Shiva S, Tsuchiya K and van Faassen EE (2009). Nitrate and nitrite in biology, nutrition and therapeutics. Nat Chem Biol  vol. 5, (12) 865-869. 10.1038/nchembio.260
Duchene J, Cayla C, Vessillier S, Scotland R, Yamashiro K, Lecomte F, Syed I, Vo P, Marrelli A, Pitzalis C, Cipollone F, Schanstra J, Bascands J-L, Hobbs AJ, Perretti M and Ahluwalia A (2009). Laminar shear stress regulates endothelial kinin B1 receptor expression and function: potential implication in atherogenesis. Arterioscler Thromb Vasc Biol  vol. 29, (11) 1757-1763. 10.1161/ATVBAHA.109.191775
Laxton RC, Hu Y, Duchene J, Zhang F, Zhang Z, Leung K-Y, Xiao Q, Scotland RS, Hodgkinson CP, Smith K, Willeit J, López-Otín C, Simpson IA, Kiechl S, Ahluwalia A, Xu Q and Ye S (2009). A role of matrix metalloproteinase-8 in atherosclerosis. Circ Res  vol. 105, (9) 921-929. 10.1161/CIRCRESAHA.109.200279
Greene S, Ahluwalia A, Watson J, Tucker R, Rourke SB, Koornstra J, Sobota M, Monette L and Byers S (2009). Between skepticism and empowerment: the experiences of peer research assistants in HIV/AIDS, housing and homelessness community‐based research. Taylor & Francis  International Journal of Social Research Methodology  vol. 12, (4) 361-373. 10.1080/13645570802553780
Greene S, Tucker R, Rourke SB, Monette L, Koornstra J, Sobota M, Byers S, Hwang S, Dunn J, Guenter D, Ahluwalia A and Watson J (2009). “Under My Umbrella”: The housing experiences of HIV positive parents who live with and care for their children in Ontario. Springer Nature  Archives of Women\'s Mental Health  vol. 13, (3) 223-232. 10.1007/s00737-009-0090-5
Kapil V, Rehman F, Arghandawi S, Milsom A, Benjamin N, Hobbs A, MacAllister R, Webb A and Ahluwalia A (2009). BLOOD PRESSURE LOWERING EFFECTS OF ORAL INORGANIC NITRATE VIA BIOCONVERSION TO NITRITE. Basic Clin Pharmacol  vol. 105, 31-31.
Okorie M, Akram F, Loukogeorgakis S, Webb A, Deanfield J, Benjamin N, Hobbs A, MacAllister R and Ahluwalia A (2009). ORAL INORGANIC NITRATE PROTECTS AGAINST ENDOTHELIAL ISCHAEMIA-REPERFUSION INJURY IN HUMANS. Basic Clin Pharmacol  vol. 105, 26-26.
Duchene J and Ahluwalia A (2009). The kinin B(1) receptor and inflammation: new therapeutic target for cardiovascular disease. Curr Opin Pharmacol  vol. 9, (2) 125-131. 10.1016/j.coph.2008.11.011
Hobbs AJ, Gane P, Lumsden N, Nobles M, Rebstock A-S, Simone M, Villar I, Worthington R, Xiao F, Ahluwalia A and Selwood D (2009). Design and development of novel non-peptide agonists at natriuretic peptide receptor-C. Faseb Journal  vol. 23, 10.1096/fasebj.23.1_supplement.756.8
Klein J, Gonzalez J, Duchene J, Esposito L, Pradere JP, Neau E, Delage C, Calise D, Ahluwalia A, Carayon P, Pesquero JB, Bader M, Schanstra JP and Bascands JL (2009). Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy. Faseb J  vol. 23, (1) 134-142. 10.1096/fj.08-115600

2008

Tolstanova G, Khomenko T, Deng X, Chen L, Tarnawski A, Ahluwalia A, Szabo S and Sandor Z (2008). Neutralizing Anti-Vascular Endothelial Growth Factor (VEGF) Antibody Reduces Severity of Experimental Ulcerative Colitis in Rats: Direct Evidence for the Pathogenic Role of VEGF. American Society For Pharmacology & Experimental Therapeutics (Aspet)  Journal of Pharmacology and Experimental Therapeutics  vol. 328, (3) 749-757. 10.1124/jpet.108.145128
Webb AJ, Milsom AB, Rathod KS, Chu WL, Qureshi S, Lovell MJ, Lecomte FMJ, Perrett D, Raimondo C, Khoshbin E, Ahmed Z, Uppal R, Benjamin N, Hobbs AJ and Ahluwalia A (2008). Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase. Circ Res  vol. 103, (9) 957-964. 10.1161/CIRCRESAHA.108.175810
Villar IC, Hobbs AJ and Ahluwalia A (2008). Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor. J Endocrinol  vol. 197, (3) 447-462. 10.1677/JOE-08-0070
Jandhyala DM, Ahluwalia A, Obrig T and Thorpe CM (2008). ZAK: a MAP3Kinase that transduces Shiga toxin‐ and ricin‐induced proinflammatory cytokine expression. Hindawi  Cellular Microbiology  vol. 10, (7) 1468-1477. 10.1111/j.1462-5822.2008.01139.x
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ and Ahluwalia A (2008). Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension  vol. 51, (3) 784-790. 10.1161/HYPERTENSIONAHA.107.103523
Webb A, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin B, Macallister R, Hobbs A and Abluwalia A (2008). Acute blood pressure lowering and vasoprotective effects of dietary nitrate. Faseb Journal  vol. 22, 10.1096/fasebj.22.1_supplement.737.30
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ and Ahluwalia A (2008). Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. American Heart Association  Hypertension  vol. 51, 784-790. 10.1161/HYPERTENSIONAHA.107.103523

2007

Duchene J, Lecomte F, Ahmed S, Cayla C, Pesquero J, Bader M, Perretti M and Ahluwalia A (2007). A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5. J Immunol  vol. 179, (7) 4849-4856. 10.4049/jimmunol.179.7.4849
Sexton A, McDonald M, Cayla C, Thiemermann C and Ahluwalia A (2007). 12-Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1. Faseb J  vol. 21, (11) 2695-2703. 10.1096/fj.06-7828com
Tarnawski A, Pai R, Deng X, Ahluwalia A, Khomenko T, Tanigawa T, Akahoshi T, Sandor Z and Szabo S (2007). Aging Gastropathy—Novel Mechanisms: Hypoxia, Up-regulation of Multifunctional Phosphatase PTEN, and Proapoptotic Factors. Elsevier  Gastroenterology  vol. 133, (6) 1938-1947.e1. 10.1053/j.gastro.2007.08.037
Villar IC, Panayiotou CM, Sheraz A, Madhani M, Scotland RS, Nobles M, Kemp-Harper B, Ahluwalia A and Hobbs AJ (2007). Definitive role for natriuretic peptide receptor-C in mediating the vasorelaxant activity of C-type natriuretic peptide and endothelium-derived hyperpolarising factor. Cardiovasc Res  vol. 74, (3) 515-525. 10.1016/j.cardiores.2007.02.032
Tripatara P, Patel NSA, Webb A, Rathod K, Lecomte FMJ, Mazzon E, Cuzzocrea S, Yaqoob MM, Ahluwalia A and Thiemermann C (2007). Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase. J Am Soc Nephrol  vol. 18, (2) 570-580. 10.1681/ASN.2006050450

2006

Villar IC, Ahluwalia A and Hobbs AJ (2006). Distinct pathways regulate endothelium derived hyperpolarising factor-mediated responses in rat mesenteric arteries. Acta Pharmacol Sin  vol. 27, (9) 1276-1276.
Villar IC, Francis S, Webb A, Hobbs AJ and Ahluwalia A (2006). Novel aspects of endothelium-dependent regulation of vascular tone. Kidney Int  vol. 70, (5) 840-853. 10.1038/sj.ki.5001680

2005

Scotland RS, Cohen M, Foster P, Lovell M, Mathur A, Ahluwalia A and Hobbs AJ (2005). C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression. P Natl Acad Sci Usa  vol. 102, (40) 14452-14457. 10.1073/pnas.0504961102
Webb A, Qureshi S, Benjamin N, Perrett D and Ahluwalia A (2005). Xanthine oxidase activity provides an alternative source of no during ischaemia from inorganic nitrite in rat blood vessels. Brit J Clin Pharmaco  vol. 59, (5) 631-632.
Ahluwalia A and Hobbs AJ (2005). Endothelium-derived C-type natriuretic peptide: more than just a hyperpolarizing factor. Trends Pharmacol Sci  vol. 26, (3) 162-167. 10.1016/j.tips.2005.01.005
Vo PA, Lad B, Tomlinson JAP, Francis S and Ahluwalia A (2005). autoregulatory role of endothelium-derived nitric oxide (NO) on Lipopolysaccharide-induced vascular inducible NO synthase expression and function. J Biol Chem  vol. 280, (8) 7236-7243. 10.1074/jbc.M411317200
Scotland RS, Madhani M, Chauhan S, Moncada S, Andresen J, Nilsson H, Hobbs AJ and Ahluwalia A (2005). Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice - Key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo. Circulation  vol. 111, (6) 796-803. 10.1161/01.CIR.0000155238.70797.4E
Scotland RS, Ahluwalia A and Hobbs AJ (2005). C-type natniuretic peptide in vascular physiology and disease. Pharmacol Therapeut  vol. 105, (2) 85-93. 10.1016/j.pharmthera.2004.08.011
Ahluwalia A, SCOTLAND RS, Andersen J, Chauhan S, Moncada S, Nilsson H, Hobbs AJ and Madhani M (2005). Investigation of Vascular Responses in Endothelial Nitric Oxide Synthase/Cyclooxygenase-1 Double-Knockout Mice: Key Role for Endothelium-Derived Hyperpolarizing Factor in the Regulation of Blood Pressure in Vivo. Circulation  vol. 111, (6) 796-803. 10.1161/01.CIR.0000155238.70797.4E
AHLUWALIA A, Scotland RS, Hobbs AJ, Moncada S, Chauhan S, Andresen J, Nilsson H and Madhani M (2005). Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo. Circulation  vol. 111, (6) 796-803.
AHLUWALIA A, Francis S, Tomlinson JA, Lad B and Vo PA (2005). role of endothelium-derived nitric oxide (NO) on Lipopolysaccharide-induced vascular inducible NO synthase expression and function. J Biol Chem  vol. 25280, (8) 7236-7243.
AHLUWALIA A, Mathur A, Lovell M, Hobbs AJ, Cohen M and Scotland RS (2005). C-type natriuretic peptide inhibits leukocyte recruitment and platelet aggregation. Pnas  vol. 102, (40) 14452-14457.

2004

Scotland RS, Chauhan S, Davis C, De Felipe C, Hunt S, Kabir J, Kotsonis P, Oh U and Ahluwalia A (2004). Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction. Circ Res  vol. 95, (10) 1027-1034. 10.1161/01.RES.0000148633.93110.24
AHLUWALIA A, Oh U, Kabir J, De Felipe C, Chauhan S, Scotland RS, Davis C, Hunt S and Kotsonis P (2004). Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction. Circ Res  vol. 95, (10) 1027-1034. 10.1161/01.RES.0000148633.93110.24
Chauhan SD, Hobbs AJ and Ahluwalia A (2004). C-type natriuretic peptide: new candidate for endothelium-derived hyperpolarising factor. Int J Biochem Cell Biol  vol. 36, (10) 1878-1881. 10.1016/j.biocel.2003.09.009
Webb A, Bond R, McLean P, Uppal R, Benjamin N and Ahluwalia A (2004). Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage. P Natl Acad Sci Usa  vol. 101, (37) 13683-13688. 10.1073/pnas.0402927101
Hobbs A, Foster P, Prescott C, Scotland R and Ahluwalia A (2004). Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury - Novel cardioprotective role for endothelium-derived C-type natriuretic peptide. Circulation  vol. 110, (10) 1231-1235. 10.1161/01.CIR.0000141802.29945.34
Ahluwalia A, MacAllister RJ and Hobbs AJ (2004). Vascular actions of natriuretic peptides. Cyclic GMP-dependent and -independent mechanisms. Basic Res Cardiol  vol. 99, (2) 83-89. 10.1007/s00395-004-0459-6
AHLUWALIA A (2004). DICHOTOMOUS ROLE OF THE ENDOTHELIUM IN LPS-INDUCED ENDOTHELIAL DYSFUNCTION. Wolters Kluwer  Shock  vol. 21, (Supplement) 10.1097/00024382-200403001-00579
Ahluwalia A, Foster P, Scotland RS, McLean PG, Mathur A, Perretti M, Moncada S and Hobbs AJ (2004). Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment. P Natl Acad Sci Usa  vol. 101, (5) 1386-1391. 10.1073/pnas.0304264101
AHLUWALIA A, Sarkar D, Aston D and McLean P (2004). Protease-activated receptor (PAR)-2 causes endothelium-dependant, NO-independant coronary vasodilatation: involvement of C-fibres and EDHF. Circ. Res  vol. 90, 465-472.
AHLUWALIA A, Hobbs A, Prescott C, Scotland R and Foster P (2004). Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide. Circulation  vol. 110, (10) 1231-1235. 10.1161/01.CIR.0000141802.29945.34
Ahluwalia A, PERRETTI M, Mathur A, Moncada S, McLean PG, Hobbs AJ, Scotland RS and Foster P (2004). Inhibition of leukocyte-endothelial cell interactions by nitric oxide via a cGMP-mediated down-regulation of P-selectin expression. Proceedings of The National Academy of Sciences Usa  vol. 101, 1386-1391.

2003

Ahluwalia A (2003). To b'EET or not to b'EET? That is the question! Clin Sci (Lond)  vol. 105, (4) 399-401. 10.1042/CS20030232
Chauhan SD, Nilsson H, Ahluwalia A and Hobbs AJ (2003). Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor. P Natl Acad Sci Usa  vol. 100, (3) 1426-1431. 10.1073/pnas.0336365100
AHLUWALIA A, Hobbs AJ, Seggara G, Chauhan SD, Vo PA and MacAllister RJ (2003). Protection against liposaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice. Faseb J  vol. 17, (6) 773-775. 10.1096/fj.02-0668fje
Chauhan S, Rahman A, Nilsson H, Clapp L, MacAllister R and Ahluwalia A (2003). NO contributes to EDHF-like responses in rat small arteries: a role for NO stores. Cardiovasc Res  vol. 57, (1) 207-216. 10.1016/s0008-6363(02)00611-9

2002

Chauhan SD, MacAllister RJ, Hobbs AJ and Ahluwalia A (2002). Mechanisms underlying the vasorelaxant activity of C-type natriuretic peptide (CNP) in rat mesenteric resistance arteries. Faseb J  vol. 16, (4) A572-A572.
McLean P and Ahluwalia A (2002). Protease-activated receptor (PAR)-2 activation causes EDHF-like coronary vasodilation: selective preservation in ischemia-reperfusion injury, involvement of lipoxygenase products, VR1 receptors and C-fibers. Faseb J  vol. 16, (4) A569-A569.
McLean PG, Aston D, Sarkar D and Ahluwalia A (2002). Protease-activated receptor-2 activation causes EDHF-like coronary vasodilation - Selective preservation in ischemia/reperfusion injury: Involvement of lipoxygenase products, VR1 receptors, and C-fibers. Circ Res  vol. 90, (4) 465-472. 10.1161/hh0402.105372
Hesslinger C, Chen Z, Ahluwalia A, Selwood DL, Vallance P, Pfeilschifter J and Hingorani AD (2002). Regulation of GTP Cyclohydrolase I by Estrogen. Chemistry and Biology of Pteridines and Folates  Springer Nature  10.1007/978-1-4615-0945-5_26

2001

Scotland RS, Chauhan S, Vallance PJ and Ahluwalia A (2001). An endothelium-derived hyperpolarizing factor-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of endothelial nitric oxide synthase-derived nitric oxide. Hypertension  vol. 38, (4) 833-839. 10.1161/hy1001.092651
Ahluwalia A (2001). Nepadutant Menarini Richerche. Curr Opin Investig Drugs  vol. 2, (7) 919-922.
Ahluwalia A, SCOTLAND RS, Vallance PJ and Chauhan S (2001). An EDHF-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of eNOS-derived nitric oxide. Hypertension  vol. 38, (4) 833-839.

2000

McLean PG, Perretti M and Ahluwalia A (2000). Kinin B1 receptors and the cardiovascular system: regulation of expression and function. Oxford University Press (Oup)  Cardiovascular Research  vol. 48, (2) 194-210. 10.1016/s0008-6363(00)00184-x
McLean PG, Ahluwalia A and Perretti M (2000). Association between Kinin B1 Receptor Expression and Leukocyte Trafficking across Mouse Mesenteric Postcapillary Venules. Rockefeller University Press  Journal of Experimental Medicine  vol. 192, (3) 367-380. 10.1084/jem.192.3.367
Scotland RS, Vallance PJT and Ahluwalia A (2000). Endogenous factors involved in regulation of tone of arterial vasa vasorum: implications for conduit vessel physiology. Oxford University Press (Oup)  Cardiovascular Research  vol. 46, (3) 403-411. 10.1016/s0008-6363(00)00023-7
PERRETTI M and AHLUWALIA A (2000). The Microcirculation and Inflammation: Site of Action for Glucocorticoids. Wiley  Microcirculation  vol. 7, (3) 147-161. 10.1111/j.1549-8719.2000.tb00117.x
Bogle RG, McLean PG, Ahluwalia A and Vallance P (2000). Impaired vascular sensitivity to nitric oxide in the coronary microvasculature after endotoxaemia. Wiley  British Journal of Pharmacology  vol. 130, (1) 118-124. 10.1038/sj.bjp.0703267
McLean PG, Perretti M and Ahluwalia A (2000). Kinin B1 receptors as novel anti-inflammatory targets. Taylor & Francis  Expert Opinion On Therapeutic Targets  vol. 4, (2) 127-141. 10.1517/14728222.4.2.127
Chauhan SD, MacAllister RJ, Clapp LH and Ahluwalia A (2000). Evidence that no may contribute to EDHF-like responses in rat mesenteric and hepatic small arteries. British Journal of Pharmacology  vol. 129,
Ahluwalia A and Scotland R (2000). Activation of sensory C-fibres partially mediates the vascular myogenic response. Faseb Journal  vol. 14, (4) A143-A143.

1999

KAKUYAMA M, AHLUWALIA A, RODRIGO J and VALLANCE P (1999). Cholinergic Contraction Is Altered in nNOS Knockouts. American Thoracic Society  American Journal of Respiratory and Critical Care Medicine  vol. 160, (6) 2072-2078. 10.1164/ajrccm.160.6.9808105
Scotland R, Vallance P and Ahluwalia A (1999). Endothelin alters the reactivity of vasa vasorum: mechanisms and implications for conduit vessel physiology and pathophysiology. Wiley  British Journal of Pharmacology  vol. 128, (6) 1229-1234. 10.1038/sj.bjp.0702930
McLean PG, Perretti M and Ahluwalia A (1999). Inducible expression of the kinin B1 receptor in the endotoxemic heart: mechanisms of des‐Arg9bradykinin‐induced coronary vasodilation. Wiley  British Journal of Pharmacology  vol. 128, (2) 275-282. 10.1038/sj.bjp.0702743
Ahluwalia A and Perretti M (1999). B1 receptors as a new inflammatory target. Could this B the 1? Elsevier  Trends in Pharmacological Sciences  vol. 20, (3) 100-104. 10.1016/s0165-6147(99)01321-8
Scotland R, Vallance P and Ahluwalia A (1999). On the regulation of tone in vasa vasorum. Oxford University Press (Oup)  Cardiovascular Research  vol. 41, (1) 237-245. 10.1016/s0008-6363(98)00223-5
McLean PG, Perretti M and Ahluwalia A (1999). The involvement of kinin B1 receptors in the hypotensive response to endotoxin in rats. British Journal of Pharmacology  vol. 127, U62-U62.
Varsani M, MacAllister R, Ahluwalia A and Marshall I (1999). Investigation of the α1 adrenoceptor subtype(s) mediating contraction in the human internal mammary artery. British Journal of Pharmacology  vol. 127,

1998

Ahluwalia A, De Felipe C, O'Brien J, Hunt SP and Perretti M (1998). Impaired IL‐1β‐induced neutrophil accumulation in tachykinin NK1 receptor knockout mice. Wiley  British Journal of Pharmacology  vol. 124, (6) 1013-1015. 10.1038/sj.bjp.0701978
Ahluwalia A, Giuliani S, Scotland R and Maggi CA (1998). Ovalbumin‐induced neurogenic inflammation in the bladder of sensitized rats. Wiley  British Journal of Pharmacology  vol. 124, (1) 190-196. 10.1038/sj.bjp.0701793
Ahluwalia A (1998). Topical glucocorticoids and the skin-mechanisms of action: an update. Hindawi  Mediators of Inflammation  vol. 7, (3) 183-193. 10.1080/09629359891126
McLean PG, Perretti M and Ahluwalia A (1998). Investigation of endotoxin-inducible B1 and constitutive B2 kinin receptors mediating coronary vasodilation in the rat isolated heart. Naunyn-Schmiedebergs Archives of Pharmacology  vol. 358, (1) R335-R335.
Kakuyama M, Vallance P and Ahluwalia A (1998). Endothelium‐dependent sensory NANC vasodilatation: involvement of ATP, CGRP and a possible NO store. Wiley  British Journal of Pharmacology  vol. 123, (2) 310-316. 10.1038/sj.bjp.0701610

1997

Ahluwalia A, Gokulan K, Nath I and Rao DN (1997). Modification of Delivery System Enhances MHC Nonrestricted Immunogenicity of V3 Loop Region of HIV‐1 gp120. Wiley  Microbiology and Immunology  vol. 41, (10) 779-784. 10.1111/j.1348-0421.1997.tb01926.x
Ahluwalia A and Vallance P (1997). Evidence for functional responses to sensory nerve stimulation of rat small mesenteric veins. Journal of Pharmacology and Experimental Therapeutics  vol. 281, (1) 9-14.
Ahluwalia A, Giuliani S and Maggi CA (1997). Allergic inflammation in the rat urinary bladder: Involvement of mast cells and C-fibres. British Journal of Pharmacology  vol. 122,
Ahluwalia A and Cellek S (1997). Regulation of the cardiovascular system by non-adrenergic non-chollnergic nerves. Wolters Kluwer  Current Opinion in Nephrology & Hypertension  vol. 6, (1) 74-79. 10.1097/00041552-199701000-00014
Scotland RS, Vallance PJ and Ahluwalia A (1997). Comparison of vascular reactivity of porcine aorta and its vasa vasorum. Circulation  vol. 96, (8) 908-908.
Kakuyama M, Vallance PJ and Ahluwalia A (1997). P-30 Non-adrenergic non-cholinergic relaxation of the rabbit mesenteric small artery: Involvement of NO. Elsevier  Journal of Pharmacological Sciences  vol. 75, 10.1016/s0021-5198(19)41531-x

1996

Halpern SM, Ahluwalia A, Makunura CN and Jordan S (1996). Investigation of notalgia paraesthetica using laser Doppler velocimetry and immunohistochemistry before and after treatment with topical capsaicin. Wiley  Journal of The European Academy of Dermatology and Venereology  vol. 7, (3) 228-234. 10.1111/j.1468-3083.1996.tb00575.x
Ahluwalia A and Vallance P (1996). Interaction between sympathetic and sensory nerves in rat small arteries: involvement of nitric oxide. American Physiological Society  American Journal of Physiology  vol. 271, (3) h969-h976. 10.1152/ajpheart.1996.271.3.h969
Perretti M, Ahluwalia A, Harris JG, Harris HJ, Wheller SK and Flower RJ (1996). Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1. Wiley  British Journal of Pharmacology  vol. 117, (6) 1145-1154. 10.1111/j.1476-5381.1996.tb16709.x
Ahluwalia A and Perretti M (1996). Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse. The American Association of Immunologists  The Journal of Immunology  vol. 156, (1) 269-274. 10.4049/jimmunol.156.1.269
Ahluwalia A and Vallance PJ (1996). Reactivity of the vasa vasorum. Circulation  vol. 94, (8) 3443-3443.

1995

Ahluwalia A, Giuliani S and Maggi CA (1995). Demonstration of a ‘septide‐sensitive’ inflammatory response in rat skin. Wiley  British Journal of Pharmacology  vol. 116, (4) 2170-2174. 10.1111/j.1476-5381.1995.tb15050.x
Ahluwalia A, Newbold P, Brain SD and Flower RJ (1995). Topical glucocorticoids inhibit neurogenic inflammation: involvement of lipocortin 1. Elsevier  European Journal of Pharmacology  vol. 283, (1-3) 193-198. 10.1016/0014-2999(95)00350-t
AHLUWALIA A, NEWBOLD P and FLOWER RJ (1995). TOPICAL GLUCOCORTICOIDS INHIBIT NEUROGENIC INFLAMMATION - INVOLVEMENT OF LIPOCORTIN-1. British Journal of Pharmacology  vol. 114, P61-P61.
AHLUWALIA A, GIULIANI S and MAGGI CA (1995). DEMONSTRATION OF A SEPTIDE-SENSITIVE INFLAMMATORY RESPONSE IN RAT SKIN. British Journal of Pharmacology  vol. 114, P41-P41.

1994

Ahluwalia A and Perretti M (1994). Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse. Elsevier  European Journal of Pharmacology  vol. 264, (3) 407-415. 10.1016/0014-2999(94)00503-6
Ahluwalia A, Mohamed RW and Flower RJ (1994). Induction of lipocortin 1 by topical steroid in rat skin. Elsevier  Biochemical Pharmacology  vol. 48, (8) 1647-1654. 10.1016/0006-2952(94)90210-0
Ahluwalia A, Maggi CA, Santicioli P, Lecci A and Giuliani S (1994). Characterization of the capsaicin‐sensitive component of cyclophosphamide‐induced inflammation in the rat urinary bladder. Wiley  British Journal of Pharmacology  vol. 111, (4) 1017-1022. 10.1111/j.1476-5381.1994.tb14845.x
Ahluwalia A and Perretti M (1994). Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors. Journal of Pharmacology and Experimental Therapeutics  vol. 268, (3) 1526-1531.
AHLUWALIA A and FLOWER RJ (1994). CHARACTERIZATION OF CAPSAICIN-INDUCED VASODILATION OF THE PERFUSED RABBIT EAR AND ITS MODULATION BY DEXAMETHASONE. British Journal of Pharmacology  vol. 112, U104-U104.

1993

Perretti M, Ahluwalia A, Harris JG, Goulding NJ and Flower RJ (1993). Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody. The American Association of Immunologists  The Journal of Immunology  vol. 151, (8) 4306-4314. 10.4049/jimmunol.151.8.4306
Perretti M, Ahluwalia A, Flower RJ and Manzini S (1993). Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors. Immunology  vol. 80, (1) 73-77.
Ahluwalia A and Flower RJ (1993). Investigations into the mechanism of vasoconstrictor action of the topical steroid betamethasone‐17‐valerate in the rat. Wiley  British Journal of Pharmacology  vol. 108, (2) 544-548. 10.1111/j.1476-5381.1993.tb12838.x
AHLUWALIA A, FLOWER RJ and PERRETTI M (1993). DUAL-ACTION OF PROSTAGLANDINS (PGS) IN THE MOUSE SKIN EDEMA TEST. British Journal of Pharmacology  vol. 109, P5-P5.
AHLUWALIA A and FLOWER RJ (1993). Topical betamethasone‐17‐valerate inhibits heat‐induced vasodilatation in man. Oxford University Press (Oup)  British Journal of Dermatology  vol. 128, (1) 45-48. 10.1111/j.1365-2133.1993.tb00146.x

1992

Ahluwalia A, Peers SH and Flower RJ (1992). Steroid inhibition of oedema formation in the rat skin. Wiley  British Journal of Pharmacology  vol. 106, (3) 628-631. 10.1111/j.1476-5381.1992.tb14386.x
AHLUWALIA A and FLOWER RJ (1992). TOPICAL STEROIDS AND ACE INHIBITORS - A COMMON LINK. British Journal of Pharmacology  vol. 106, P5-P5.

Grants

Grants of specific relevance to Predictive in vitro Models
NIHR Barts BRC
Ahluwalia A
£20,994,785 NIHR (01-12-2022 - 30-11-2027)
QMUL 1st intake 2021 4-Year PhD Studentship (5th) Scheme: Ms Nicola Dark; Ms Christina Gkantsinikoudi; Mr Thomas Wright
Ahluwalia A
£444,465 British Heart Foundation (01-10-2021 - 30-09-2025)
QMUL 4th intake 2020 4-Year PhD Studentship (4th) Scheme
Ahluwalia A
£594,796 British Heart Foundation (01-10-2020 - 30-09-2024)


Queen Mary 3rd intake 2019 4-Year PhD Studentship (4th) Scheme: Ms Laura Deelen; Nicki Dyson; Ms Trupti Kolvekar; Mr Balraj Singh Sandhar
Ahluwalia A
£702,757 British Heart Foundation (01-10-2019 - 30-09-2023)
QMUL 2nd intake 2018 4-Year PhD Studentship (4th) Scheme: Ms Silvia Fanti; Ms Hannah Nicholls; Ms Kaya Olczak; Mr Darren Wilson (4 years)
Ahluwalia A
£652,264 British Heart Foundation (01-10-2018 - 30-09-2022)
QMUL 1st intake 2017 4 Year PhD Studentship (4th) Scheme: Mr Joshua Dignam; Ms Shireen Mohammad; Ms Nur Mousa; Mr Stefan Russo (4 years)
Ahluwalia A
£649,024 British Heart Foundation (01-10-2017 - 30-09-2021)
Investigation of the therapeutic potential of dietary nitrate in atherosclerosis
Ahluwalia A
£196,410 British Heart Foundation (28-09-2010 - 30-09-2013)
Characterisation of the physiological roles and pathological significance of endothelium-derived C-type natriuretic peptide: a novel vasoprotective signalling paradigm.
Hobbs AJ, Ahluwalia A and Tinker A
£476,952 Wellcome Trust (04-11-2008 - 03-07-2011)
Summary
Vascular autoregulation and inflammation: Role of sensory C-fibres and TRPV1.
Ahluwalia A, Baker MD and Priestley JV
£353,189 Wellcome Trust (01-09-2007 - 31-08-2010)
Summary
Design and development of novel non-peptide agonists at the natriuretic peptide receptor-C and evaluation of therapeutic potential for cardiovascular disease
Hobbs AJ, Ahluwalia A, Madge DJ and Selwood DL
£733,988 Wellcome Trust (09-01-2006 - 08-03-2009)
Summary
Mechanisms regulating expression and function of the kinin B1 receptor in cardiovascular inflammation.
Ahluwalia A and Perretti M
£299,837 Wellcome Trust (01-11-2002 - 31-07-2007)
Summary
Design and development of novel non-peptide agonists at the natriuretic peptide receptor-C and evaluation of therapeutic potential for cardiovascular disease
Hobbs AJ, Ahluwalia A and Madge DJ
£50,000 Wellcome Trust (01-12-2004 - 30-11-2005)
Summary
Characterisation of C-type natriuretic peptide (CNP) as an endothelium-derivedhyperpolarising factor: regulation of vascular tone, and platelet reactivity.
Hobbs AJ, Ahluwalia A, Leaney JL and Scotland RS
£130,460 Wellcome Trust (01-04-2003 - 31-05-2005)
Summary
Intravital microscopy set up.
Ahluwalia A, Hobbs AJ and Vallance PJ
£71,208 Wellcome Trust (01-07-2001 - 30-09-2002)
Summary