Prof Amrita Ahluwalia

Dean For Research Faculty of Medicine and Dentistry

The William Harvey Research Institute
Queen Mary University of London

a.ahluwalia@qmul.ac.uk

www.qmul.ac.uk/whri/people/academic-staff/items/ahluwaliaamrita.html

Research
Publications
Grants

Research

Sex differences, Nitrite/Nitrate/Nitric oxide, Xanthine oxidoreductase, inflammation, cardiovascular

Cardiovascular Models

Interests

Sex differences in drug action related to treatment of cardiovascular disease is neglected, however, most drugs removed for use by the FDA relate to adverse effects in women. I am interested in exploring sex differences using in vitro models.
Separately the enzyme xanthine oxidoreductase has been implicated in cardiovascular disease development. We have developed small molecules that target this enzyme and identified rare mutations that are linked with disease. Exploring drug action in genetic models in vitro is of interest.

Publications

2025

Recent innovations in targeting redox biology for therapeutics
Cortese‐Krott MM, Fukuto JM, Ahluwalia A
British Journal of Pharmacology, Wiley

DOI 10.1111/bph.70156

21-08-2025

Accelerating inflammatory resolution in humans to improve endothelial function and vascular health: Targeting the non-canonical pathway for NO
Lau C, Primus CP, Shabbir A, Chhetri I, Ono M, Masucci M, Bin Noorany Aubdool MA, Amarin J et al.
Redox Biology, Elsevier Bv vol. 82, 103592-103592.

DOI 10.1016/j.redox.2025.103592

01-05-2025

Addressing cultural and knowledge barriers to enable preclinical sex inclusive research
Gaskill BN, Phillips B, Ho J, Rafferty H, Onada OO, Rooney A, Ahluwalia A, Karp NA
In Cold Spring Harbor Laboratory

DOI 10.1101/2025.03.18.643949

19-03-2025

Introduction to the Theme “Novel Therapeutics with the Potential to Advance Health Care”
Insel PA, Amara SG, Ahluwalia A
Annual Review of Pharmacology and Toxicology, Annual Reviews vol. 65 (1), 1-5.

DOI 10.1146/annurev-pharmtox-090324-021727

QMRO

23-01-2025

2024

CTCA Prior to Invasive Coronary Angiography in Patients With Previous Bypass Surgery: Patient-Related Outcomes, Imaging Resource Utilization, and Cardiac Events at 3 Years From the BYPASS-CTCA Trial
Kelham M, Beirne A-M, Rathod KS, Andiapen M, Wynne L, Learoyd AE, Forooghi N, Ramaseshan R et al.
Circulation: Cardiovascular Interventions, Ovid Technologies (Wolters Kluwer Health) vol. 17 (12)

DOI 10.1161/circinterventions.124.014142

01-12-2024

Potential Opportunities for Pharmacogenetic-Based Therapeutic Exploitation of Xanthine Dehydrogenase in Cardiovascular Disease
Massimo G, Dyson N, Olotu F, Khambata RS, Ahluwalia A
Antioxidants, Mdpi Ag vol. 13 (12), 1439-1439.

DOI 10.3390/antiox13121439

QMRO

22-11-2024

The nitrite reductase activity of xanthine oxidoreductase sustains cardiovascular health
Dyson N, Khambata RS, Parakaw T, Massimo G, Khuat NHH, Noor AA, Gee LC, Lim I et al.
In Cold Spring Harbor Laboratory

DOI 10.1101/2024.11.01.621390

03-11-2024

The NITRATE-OCT study-inorganic nitrate reduces in-stent restenosis in patients with stable coronary artery disease: a double-blind, randomised controlled trial
Rathod KS, Mathur A, Shabbir A, Khambata RS, Lau C, Beirne A-M, Chhetri I, Ono M et al.
Eclinicalmedicine, Elsevier Bv vol. 77, 102885-102885.

DOI 10.1016/j.eclinm.2024.102885

QMRO

01-11-2024

OP5 Diagnostic accuracy of CTCA for graft and native disease assessment in patients with previous CABG: insights from the BYPASS-CTCA trial
Vyas R, Kelham M, Beirne A-M, Rathod KS, Andiapen M, Wynne L, Learoyd AE, Forooghi N et al.
BSCI/BSCCT Annual Meeting 2024.

DOI 10.1136/heartjnl-2024-bsci.5

01-09-2024

The effect of CTCA guided selective invasive graft assessment on coronary angiographic parameters and outcomes: Insights from the BYPASS-CTCA trial
Kelham M, Beirne A-M, Rathod KS, Andiapen M, Wynne L, Ramaseshan R, Learoyd AE, Forooghi N et al.
Journal of Cardiovascular Computed Tomography, Elsevier Bv vol. 18 (3), 291-296.

DOI 10.1016/j.jcct.2024.03.004

QMRO

01-05-2024

Inorganic nitrate benefits contrast-induced nephropathy after coronary angiography for acute coronary syndromes: the NITRATE-CIN trial
Jones DA, Beirne A-M, Kelham M, Wynne L, Andiapen M, Rathod KS, Parakaw T, Adams J et al.
European Heart Journal, Oxford University Press (Oup) vol. 45 (18), 1647-1658.

DOI 10.1093/eurheartj/ehae100

QMRO

21-03-2024

2023

Inhaled nitric oxide suppresses neuroinflammation in experimental ischemic stroke
Sienel RI, Mamrak U, Biller J, Roth S, Zellner A, Parakaw T, Khambata RS, Liesz A et al.
Journal of Neuroinflammation, Springer Science and Business Media Llc vol. 20 (1)

DOI 10.1186/s12974-023-02988-3

QMRO

15-12-2023

Natural mutations of human XDH promote the nitrite (NO2−)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?
Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod KS et al.
Redox Biology, Elsevier Bv vol. 67, 102864-102864.

DOI 10.1016/j.redox.2023.102864

QMRO

01-11-2023

Corrigendum to “Natural mutations of human XDH promote the nitrite (NO2−)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?” [Redox Biol. 4 (67) (2023) 102864]
Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod K et al.
Redox Biology, Elsevier Bv vol. 67, 102925-102925.

DOI 10.1016/j.redox.2023.102925

QMRO

01-11-2023

Computed Tomography Cardiac Angiography Before Invasive Coronary Angiography in Patients With Previous Bypass Surgery: The BYPASS-CTCA Trial
Jones DA, Beirne A-M, Kelham M, Rathod KS, Andiapen M, Wynne L, Godec T, Forooghi N et al.
Circulation, Ovid Technologies (Wolters Kluwer Health) vol. 148 (18), 1371-1380.

DOI 10.1161/circulationaha.123.064465

QMRO

31-10-2023

A double-blind, randomised, placebo-controlled parallel study to investigate the effect of sex and dietary nitrate on COVID-19 vaccine-induced vascular dysfunction in healthy men and women: protocol of the DiNOVasc-COVID-19 study
Shabbir A, Chhetri I, Khambata RS, Parakaw T, Lau C, Aubdool MABN, Massimo G, Dyson N et al.
Trials, Springer Science and Business Media Llc vol. 24 (1)

DOI 10.1186/s13063-023-07616-2

QMRO

16-09-2023

34 Investigation of the effects of dietary nitrate on vascular function, platelet reactivity and restenosis in patients with stable angina (nitrate-oct study)
Rathod K, Warren H, Tufaro V, Jain A, Ono M, Chhetri I, Garcia-Garcia H, Bourantas C et al.
British Cardiovascular Society Annual Conference, ‘Future-proofing Cardiology for the next 10 years’, 5–7 June 2023.

DOI 10.1136/heartjnl-2023-bcs.34

01-06-2023

D Investigation of the effects of dietary nitrate on vascular function, platelet reactivity and restenosis in patients with stable angina (NITRATE-OCT study)
Rathod KS, Shabbir A, Jones DA, Khambata RS, Lau C, Beirne A-M, Ono M, Chhetri I et al.
British Cardiovascular Society Annual Conference, ‘Future-proofing Cardiology for the next 10 years’, 5–7 June 2023.

DOI 10.1136/heartjnl-2023-bcs.302

01-06-2023

Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow
Bosseboeuf E, Chikh A, Chaker AB, Mitchell TP, Vignaraja D, Rajendrakumar R, Khambata RS, Nightingale TD et al.
Science Signaling, American Association For The Advancement of Science (Aaas) vol. 16 (786)

DOI 10.1126/scisignal.abo4863

QMRO

23-05-2023

BJP recommendations for publishing research on tobacco smoke and environmental tobacco smoke exposure
Panettieri RA, Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y et al.
British Journal of Pharmacology, Wiley vol. 180 (12), 1537-1541.

DOI 10.1111/bph.16089

QMRO

24-04-2023

Sodium nitrite poisoning: A series of 20 fatalities in which post-mortem blood nitrite and nitrate concentrations are reported
Hikin LJ, Ho J, Morley SR, Ahluwalia A, Smith PR
Forensic Science International, Elsevier Bv vol. 345, 111610-111610.

DOI 10.1016/j.forsciint.2023.111610

QMRO

01-04-2023

Natural mutations of humanXDHpromote the nitrite (NO₂^-)-reductase capacity of xanthine oxidoreductase: a novel mechanism to promote redox health?
Massimo G, Khambata RS, Chapman T, Birchall K, Shabbir A, Dyson N, Rathod K, Borghi C et al.
In Cold Spring Harbor Laboratory

DOI 10.1101/2023.03.24.533749

24-03-2023

Considering and reporting sex as an experimental variable II: An update on progress in the British Journal of Pharmacology
Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y, Panettieri RA et al.
British Journal of Pharmacology, Wiley vol. 180 (9), 1191-1196.

DOI 10.1111/bph.16049

QMRO

06-03-2023

Local delivery of nitric oxide prevents endothelial dysfunction in periodontitis
Fernandes D, Khambata RS, Massimo G, Ruivo E, Gee LC, Foster J, Goddard A, Curtis M et al.
Pharmacological Research, Elsevier Bv vol. 188, 106616-106616.

DOI 10.1016/j.phrs.2022.106616

QMRO

01-02-2023

Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans
Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC et al.
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 133 (2)

DOI 10.1172/jci168068

QMRO

17-01-2023

Local delivery of nitric oxide prevents endothelial dysfunction in periodontitis
Khambata R, Fernandes D, Massimo G, Ruivo E, Gee LC, Foster J, Goddard A, Curtis M et al.

QMRO

01-01-2023

Nitrite reductase activity of liver-derived Xanthine Oxidoreductase maintains cardiovascular homeostasis
Dyson N, Khambata R, Massimo G, Parakaw T, Rathod K, Ahluwalia A

QMRO

01-01-2023

Natural Mutations Of Human Xdh Promote The Nitirte (No2-)-Reductase Capacity Of Xanthine Oxidoreductase: A Novel Mechanism To Promote Redox Health?
Massimo G, Khambata R, Chapman T, Birchall K, Borghi C, Ahluwalia A

QMRO

01-01-2023

Considering And Reporting Sex As An Experimental Variable: An Update On Progress In The British Journal Of Pharmacology
Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Panettieri RAJ, Patel HH et al.

QMRO

01-01-2023

2022

Guidance for the use and reporting of anaesthetic agents inBJPmanuscripts involving work with animals
Ingrande J, Patel HH, Kendall D, Stefanska B, Alexander S, Bakhle M, Cirino G, Docherty JR et al.
British Journal of Pharmacology, Wiley vol. 180 (3), 255-263.

DOI 10.1111/bph.15992

QMRO

18-12-2022

Sodium nitrite poisoning; A case series of 15 fatalities
Hikin L, Ahluwalia A, Morley S, Smith P
Toxicologie Analytique Et Clinique, Elsevier Bv vol. 34 (3), S48-S49.

DOI 10.1016/j.toxac.2022.06.056

QMRO

01-09-2022

Planning experiments: Updated guidance on experimental design and analysis and their reporting III
Curtis MJ, Alexander SPH, Cirino G, George CH, Kendall DA, Insel PA, Izzo AA, Ji Y et al.
British Journal of Pharmacology, Wiley vol. 179 (15), 3907-3913.

DOI 10.1111/bph.15868

QMRO

07-06-2022

BS37 Leukocytic nitrate reductase activity mitigates systemic inflammation-induced endothelial dysfunction in humans by accelerating resolution
Shabbir A, Rathod K, Primus C, Lau C, Chhetri I, Ono M, Khambata R, Massimo G et al.
British Cardiovascular Society Annual Conference, ‘100 years of Cardiology’, 6–8 June 2022.

DOI 10.1136/heartjnl-2022-bcs.217

QMRO

01-06-2022

Sex differences and sex bias in human circadian and sleep physiology research
Spitschan M, Santhi N, Ahluwalia A, Fischer D, Hunt L, Karp NA, Lévi F, Pineda-Torra I et al.
Elife, Elife Sciences Publications, Ltd vol. 11

DOI 10.7554/elife.65419

QMRO

18-02-2022

20‐hydroxyeicosatetraenoic acid (20‐HETE) is a pivotal endogenous ligand for TRPV1‐mediated neurogenic inflammation in the skin
Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Montalvo Moreira SA, Rathod K, Chen J et al.
British Journal of Pharmacology, Wiley vol. 179 (7), 1450-1469.

DOI 10.1111/bph.15726

QMRO

14-02-2022

2021

Serum nitrite and nitrate: A potential biomarker for post-covid-19 complications?
Wang J, Mei F, Bai L, Zhou S, Liu D, Yao L, Ahluwalia A, Ghiladi RA et al.
Free Radical Biology and Medicine, Elsevier Bv vol. 175, 216-225.

DOI 10.1016/j.freeradbiomed.2021.08.237

QMRO

01-11-2021

Molecular imaging—The first visual themed issue published in the British Journal of Pharmacology
Maffia P, Antoniades C, Ahluwalia A, Cirino G
British Journal of Pharmacology, Wiley vol. 178 (21), 4213-4215.

DOI 10.1111/bph.15632

QMRO

19-10-2021

Inorganic nitrate attenuates endothelial dysfunction consequent to systemic inflammation
Lau C, Shabbir A, Rathod KS, Chhetri I, Ono M, Hamers AJP, Amarin JJ, Ibrahim A et al.
European Heart Journal, Oxford University Press (Oup) vol. 42 (Supplement_1)

DOI 10.1093/eurheartj/ehab724.3008

QMRO

12-10-2021

A pro-resolving phenotype underpins the anti-inflammatory effects of inorganic nitrate
Primus C, Masucci M, Whitear C, Montalvo Moreira SA, Ajit Kumar N, Chhetri I, Rathod KS, Khambata R et al.
European Heart Journal, Oxford University Press (Oup) vol. 42 (Supplement_1)

DOI 10.1093/eurheartj/ehab724.3352

QMRO

12-10-2021

Inorganic nitrate attenuates the systemic inflammatory response in typhoid vaccine-induced endothelial dysfunction in healthy volunteers
Shabbir A, Lau C, Rathod KS, Chhetri I, Haque A, Godec T, Khambata RS, Kapil V et al.
European Heart Journal, Oxford University Press (Oup) vol. 42 (Supplement_1)

DOI 10.1093/eurheartj/ehab724.3009

QMRO

12-10-2021

Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide
Gee LC, Massimo G, Lau C, Primus C, Fernandes D, Chen J, Rathod KS, Hamers AJP et al.
British Journal of Pharmacology, Wiley vol. 179 (20), 4757-4777.

DOI 10.1111/bph.15636

QMRO

06-10-2021

The BYPASS-CTCA Study: the value of Computed Tomography Cardiac Angiography (CTCA) in improving patient-related outcomes in patients with previous bypass operation undergoing invasive coronary angiography: Study Protocol of a Randomised Controlled Trial
Beirne A-M, Rathod KS, Castle E, Andiapen M, Richards A, Bellin A, Hammond V, Godec T et al.
Annals of Translational Medicine, Ame Publishing Company vol. 9 (17), 1395-1395.

DOI 10.21037/atm-21-1455

QMRO

01-09-2021

Editorial policy regarding the citation of preprints in the British Journal of Pharmacology (BJP)
George CH, Alexander SPH, Cirino G, Insel PA, Izzo AA, Ji Y, Kendall DA, Panettieri RA et al.
British Journal of Pharmacology, Wiley vol. 178 (18), 3605-3610.

DOI 10.1111/bph.15589

QMRO

30-07-2021

NITRATE-CIN Study: Protocol of a Randomized (1:1) Single-Center, UK, Double-Blind Placebo-Controlled Trial Testing the Effect of Inorganic Nitrate on Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography for Acute Coronary Syndromes
Beirne A-M, Mitchelmore O, Palma S, Andiapen M, Rathod KS, Hammond V, Bellin A, Cooper J et al.
Journal of Cardiovascular Pharmacology and Therapeutics, Sage Publications vol. 26 (4), 303-309.

DOI 10.1177/1074248421000520

QMRO

25-03-2021

Sex Differences in the Inflammatory Response: Pharmacological Opportunities for Therapeutics for Coronary Artery Disease
Shabbir A, Rathod KS, Khambata RS, Ahluwalia A
Annual Review of Pharmacology and Toxicology, Annual Reviews vol. 61 (1), 333-359.

DOI 10.1146/annurev-pharmtox-010919-023229

QMRO

06-01-2021

The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction
Rathod KS, Jones DA, Jain AK, Lim P, MacCarthy PA, Rakhit R, Lockie T, Kalra S et al.
American Journal of Cardiovascular Disease vol. 11 (5), 659-+.

QMRO

01-01-2021

QMRO

01-01-2021

2020

Therapeutic Implications of COVID-19 for the Interventional Cardiologist
Kelham M, Choudry FA, Hamshere S, Beirne A-M, Rathod KS, Baumbach A, Ahluwalia A, Mathur A et al.
Journal of Cardiovascular Pharmacology and Therapeutics, Sage Publications vol. 26 (3), 203-216.

DOI 10.1177/1074248420982736

QMRO

17-12-2020

Second wave and second opportunity: capitalizing on cardiovascular research activity during the COVID-19 pandemic
Shabbir A, Ahluwalia A
European Heart Journal - Quality of Care and Clinical Outcomes, Oxford University Press (Oup) vol. 7 (3), 321-322.

DOI 10.1093/ehjqcco/qcaa087

QMRO

23-11-2020

The ARRIVE guidelines 2.0: updated guidelines for reporting animal\n\t\t\t\t\t\tresearchThe ARRIVE guidelines 2.0: updated guidelines for reporting animal\n\t\t\t\t\t\tresearch
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al.
Bmj Open Science, Portico vol. 44 (11)

DOI 10.1136/bmjos-2020-100115

20-07-2020

ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020
Lilley E, Stanford SC, Kendall DE, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA et al.
British Journal of Pharmacology, Wiley vol. 177 (16), 3611-3616.

DOI 10.1111/bph.15178

14-07-2020

The ARRIVE guidelines 2.0: updated guidelines for reporting animal research
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al.
The Journal of Physiology, Wiley vol. 598 (18), 3793-3801.

DOI 10.1113/jp280389

14-07-2020

Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
Percie du Sert N, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC et al.
Plos Biology, Public Library of Science (Plos) vol. 18 (7), e3000411-e3000411.

DOI 10.1371/journal.pbio.3000411

14-07-2020

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research*
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al.
Journal of Cerebral Blood Flow &Amp; Metabolism, Sage Publications vol. 40 (9), 1769-1777.

DOI 10.1177/0271678x20943823

14-07-2020

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al.
Plos Biology, Public Library of Science (Plos) vol. 18 (7), e3000410-e3000410.

DOI 10.1371/journal.pbio.3000410

14-07-2020

The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway
Kapil V, Khambata RS, Jones DA, Rathod K, Primus C, Massimo G, Fukuto JM, Ahluwalia A
Pharmacological Reviews, Elsevier Bv vol. 72 (3), 692-766.

DOI 10.1124/pr.120.019240

QMRO

01-07-2020

The many mechanisms of action of Chloroquine: to use or not to use (in COVID‐19) that is the question
Cirino G, Ahluwalia A
British Journal of Pharmacology, Wiley vol. 177 (15), 3361-3362.

DOI 10.1111/bph.15177

QMRO

30-06-2020

Research priorities for rehabilitation and aging with HIV: a framework from the Canada-International HIV and Rehabilitation Research Collaborative (CIHRRC)
O'Brien KK, Ibáñez-Carrasco F, Solomon P, Harding R, Brown D, Ahluwalia P, Carusone SC, Baxter L et al.
In Springer Science and Business Media Llc

DOI 10.21203/rs.2.20149/v2

14-05-2020

A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: Reproducibility of natural product research
Izzo AA, Teixeira M, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA, Ji Y et al.
British Journal of Pharmacology, Wiley vol. 177 (10), 2169-2178.

DOI 10.1111/bph.15054

QMRO

16-04-2020

DOI 10.21203/rs.2.20149/v1

07-01-2020

Randomised, double-blind, placebo-controlled clinical trial investigating the effects of inorganic nitrate in hypertension-induced target organ damage: protocol of the NITRATE-TOD study in the UK
Lau CWZ, Hamers AJP, Rathod KS, Shabbir A, Cooper J, Primus CP, Davies C, Mathur A et al.
Bmj Open, Bmj vol. 10 (1), e034399-e034399.

DOI 10.1136/bmjopen-2019-034399

QMRO

01-01-2020

2019

Ergocalciferol improves endothelial vasodilatory and vasoconstrictor function in an in vivo model of mild uraemia
Dreyer G, Kieswich J, Harwood S, Ahluwalia A, Yaqoob MM
Bioscience Reports, Portland Press Ltd. vol. 39 (12)

DOI 10.1042/bsr20190711

QMRO

17-12-2019

The BJP expects authors to share data
George CH, Alexander SPH, Cirino G, Docherty JR, Hoyer D, Insel PA, Izzo AA, Ji Y et al.
British Journal of Pharmacology, Wiley vol. 176 (24), 4595-4598.

DOI 10.1111/bph.14907

QMRO

01-12-2019

Natural Mutations of the Human Xdh Impact upon the Nitric Oxide-generating Capacity of Xanthine Oxidoreductase

DOI 10.1016/j.freeradbiomed.2019.10.310

QMRO

01-12-2019

The pharmacology of itch
Ingram JR, Ahluwalia A
British Journal of Pharmacology, Wiley vol. 176 (23), 4419-4420.

DOI 10.1111/bph.14865

QMRO

14-10-2019

The pharmacology of itch
Ingram JR, Ahluwalia A
British Journal of Dermatology, Oxford University Press (Oup) vol. 184 (1)

DOI 10.1111/bjd.18525

QMRO

03-10-2019

Corrigendum to “The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction” [Int. J. Cardiol. 266 (2018) 1–6]
Jones DA, Rathod KS, Williamson A, Mand K, Harrington D, Andiapen M, van Eijl S, Westwood M et al.
International Journal of Cardiology, Elsevier Bv vol. 292, 284-284.

DOI 10.1016/j.ijcard.2019.04.076

QMRO

01-10-2019

Letter by Jones et al Regarding Article, “Optimized Treatment of ST-Elevation Myocardial Infarction”
Jones DA, Mathur A, Ahluwalia A
Circulation Research, Ovid Technologies (Wolters Kluwer Health) vol. 125 (6)

DOI 10.1161/circresaha.119.315692

QMRO

30-08-2019

Sex: A change in our guidelines to authors to ensure that this is no longer an ignored experimental variable
Docherty JR, Stanford SC, Panettieri RA, Alexander SPH, Cirino G, George CH, Hoyer D, Izzo AA et al.
British Journal of Pharmacology, Wiley vol. 176 (21), 4081-4086.

DOI 10.1111/bph.14761

QMRO

23-08-2019

Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019
Percie du Sert N, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC et al.

DOI 10.1101/703355

15-07-2019

The ARRIVE guidelines 2019: updated guidelines for reporting animal research
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al.

DOI 10.1101/703181

15-07-2019

Plan S: in Service or Disservice to Society?
Guzik TJ, Ahluwalia A
European Heart Journal, Oxford University Press (Oup) vol. 40 (12), 949-952.

DOI 10.1093/eurheartj/ehz065

QMRO

21-03-2019

Plan S: In service or disservice to society?
Guzik TJ, Ahluwalia A
British Journal of Pharmacology, Wiley vol. 176 (6), 753-756.

DOI 10.1111/bph.14590

QMRO

27-02-2019

2018

Inorganic Nitrate as a Regulator of Vascular Function
Ahluwalia A

DOI 10.1016/j.freeradbiomed.2018.10.376

QMRO

01-11-2018

Sex differences in the nitrate-nitrite-NO• pathway: Role of oral nitrate-reducing bacteria
Kapil V, Rathod KS, Khambata RS, Bahra M, Velmurugan S, Purba A, S. Watson D, Barnes MR et al.
Free Radical Biology and Medicine, Elsevier Bv vol. 126, 113-121.

DOI 10.1016/j.freeradbiomed.2018.07.010

QMRO

01-10-2018

The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction
Jones DA, Rathod KS, Williamson A, Harrington D, Andiapen M, van Eijl S, Westwood M, Antoniou S et al.
International Journal of Cardiology, Elsevier Bv vol. 266, 1-6.

DOI 10.1016/j.ijcard.2018.01.029

QMRO

01-09-2018

Clarification of the basis for the selection of requirements for publication in the British Journal of Pharmacology
Curtis MJ, Ashton JC, Moon LDF, Ahluwalia A
British Journal of Pharmacology, Wiley vol. 175 (18), 3633-3635.

DOI 10.1111/bph.14443

24-08-2018

Sodium Nitrite–Mediated Cardioprotection in Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: A Cost-Effectiveness Analysis
Jones DA, Whittaker P, Rathod KS, Richards AJ, Andiapen M, Antoniou S, Mathur A, Ahluwalia A
Journal of Cardiovascular Pharmacology and Therapeutics, Sage Publications vol. 24 (2), 113-119.

DOI 10.1177/1074248418784940

QMRO

06-08-2018

P2564Sodium nitrite-mediated cardioprotection in primary percutaneous coronary intervention for ST-elevation myocardial infarction: a cost-effectiveness analysis
Jones DA, Whittaker P, Rathod KS, Richards AJ, Andiapen M, Antoniou S, Mathur A, Ahluwalia A
European Heart Journal, Oxford University Press (Oup) vol. 39 (suppl_1)

DOI 10.1093/eurheartj/ehy565.p2564

01-08-2018

Launch of mini‐reviews in hot topics
Ahluwalia A, Cirino G
British Journal of Pharmacology, Wiley vol. 175 (13), 2537-2537.

DOI 10.1111/bph.14342

QMRO

15-06-2018

Revision of the ARRIVE guidelines: rationale and scope
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Altman DG, Avey MT, Baker M, Browne W et al.
Bmj Open Science, Portico vol. 2 (1)

DOI 10.1136/bmjos-2018-000002

12-06-2018

The GTN patch: a simple and effective new approach to cardioprotection?
Yellon DM, He Z, Khambata R, Ahluwalia A, Davidson SM
Basic Research in Cardiology, Springer Science and Business Media Llc vol. 113 (3)

DOI 10.1007/s00395-018-0681-2

QMRO

17-04-2018

Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers
Curtis MJ, Alexander S, Cirino G, Docherty JR, George CH, Giembycz MA, Hoyer D, Insel PA et al.
British Journal of Pharmacology, Wiley vol. 175 (7), 987-993.

DOI 10.1111/bph.14153

QMRO

09-03-2018

Endogenously generated arachidonate‐derived ligands for TRPV1 induce cardiac protection in sepsis
Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J et al.
The Faseb Journal, Wiley vol. 32 (7), 3816-3831.

DOI 10.1096/fj.201701303r

QMRO

20-02-2018

Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology
Alexander SPH, Roberts RE, Broughton BRS, Sobey CG, George CH, Stanford SC, Cirino G, Docherty JR et al.
British Journal of Pharmacology, Wiley vol. 175 (3), 407-411.

DOI 10.1111/bph.14112

QMRO

19-01-2018

Sodium nitrite-mediated cardioprotection in primary percutaneous coronary intervention for ST-elevation myocardial infarction: a cost-effectiveness analysis
Jones DA, Whittaker P, Rathod KS, Richards AJ, Andiapen M, Antoniou S, Mathur A, Ahluwalia A

QMRO

01-01-2018

2017

NGF protects endothelial cells from indomethacin-induced injury through activation of mitochondria and upregulation of IGF-1
Ahluwalia A, Jones MK, Hoa N, Tarnawski AS
Cellular Signalling, Elsevier Bv vol. 40, 22-29.

DOI 10.1016/j.cellsig.2017.08.006

01-12-2017

Letter to the editor - round table unites to\ntackle culture change in an effort to improve animal research reporting
Osborne NJ, Ritskes-Hoitinga M, Ahluwahlia A, Alam S, Brown M, Henderson H, de Leeuw W, Marsh J et al.
Bmc Veterinary Research, Springer Science and Business Media Llc vol. 13 (1)

DOI 10.1186/s12917-017-1235-9

QMRO

07-11-2017

Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials
Campo G, Pavasini R, Morciano G, Lincoff AM, Gibson CM, Kitakaze M, Lonborg J, Ahluwalia A et al.
International Journal of Cardiology, Elsevier Bv vol. 244, 59-66.

DOI 10.1016/j.ijcard.2017.06.040

QMRO

01-10-2017

Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention
Campo G, Pavasini R, Morciano G, Lincoff MA, C. Gibson M, Kitakaze M, Lonborg J, Ahluwalia A et al.
Data in Brief, Elsevier Bv vol. 14, 197-205.

DOI 10.1016/j.dib.2017.07.033

QMRO

01-10-2017

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications
Todd Milne G, Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS et al.
Bmc Pharmacology and Toxicology, Springer Science and Business Media Llc vol. 18 (S1)

DOI 10.1186/s40360-017-0170-5

QMRO

01-10-2017

Updating the guidelines for data transparency in the British Journal of Pharmacology – data sharing and the use of scatter plots instead of bar charts
George CH, Stanford SC, Alexander S, Cirino G, Docherty JR, Giembycz MA, Hoyer D, Insel PA et al.
British Journal of Pharmacology, Wiley vol. 174 (17), 2801-2804.

DOI 10.1111/bph.13925

QMRO

11-08-2017

Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1
Yuzugulen J, Douthwaite JA, Wood EG, Villar IC, Patel NSA, Jegard J, Gaertner H, Rossitto-Borlat I et al.
Scientific Reports, Springer Science and Business Media Llc vol. 7 (1)

DOI 10.1038/s41598-017-05365-2

QMRO

10-07-2017

Arachidonic acid metabolites induce TRPV1‐mediated inflammation
Hamers AJP, Ahluwalia A

DOI 10.1096/fasebj.31.1_supplement.825.5

01-04-2017

Sex differences in the inflammatory response and inflammation-induced vascular dysfunction
Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, Gee L, Bansal J et al.

DOI 10.1016/s0140-6736(17)30416-6

QMRO

01-02-2017

Antiinflammatory actions of inorganic nitrate stabilize the atherosclerotic plaque
Khambata RS, Ghosh SM, Rathod KS, Thevathasan T, Filomena F, Xiao Q, Ahluwalia A
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 114 (4)

DOI 10.1073/pnas.1613063114

QMRO

05-01-2017

Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation
Jones DA, Rathod KS, Ahluwalia A
In Nitric Oxide, Elsevier 195-211.

DOI 10.1016/b978-0-12-804273-1.00015-6

01-01-2017

Combined analysis of the safety of intra-coronary drug delivery during primary percutaneous coronary intervention for acute myocardial infarction: A study of three clinical trials
Rathod KS, Hamshere S, Khambata RS, Andiapen M, Westwood M, Mathur A, Ahluwalia A, Jones DA
Jrsm Cardiovascular Disease, Sage Publications vol. 6

DOI 10.1177/2048004017725988

QMRO

01-01-2017

Chapter 15 Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation
Jones DA, Rathod KS, Ahluwalia A
In Nitric Oxide, Elsevier 195-211.

DOI 10.1016/b978-0-12-804273-1.00015-6

01-01-2017

Effects of Dietary Nitrate on Blood Pressure-dependent and Independent Cardiac Dysfunction
Gee LC, Massimo G, Rathod KS, Fernandes D, Ahluwalia A

01-01-2017

2016

Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study
Rathod KS, Jones DA, Van-Eijl TJA, Tsang H, Warren H, Hamshere SM, Kapil V, Jain AK et al.
Bmj Open, Bmj vol. 6 (12), e012728-e012728.

DOI 10.1136/bmjopen-2016-012728

QMRO

01-12-2016

DOI 10.1172/jci89429

QMRO

28-11-2016

Nerve growth factor is critical requirement for in vitro angiogenesis in gastric endothelial cells
Ahluwalia A, Jones MK, Brzozowski T, Tarnawski AS
American Journal of Physiology-Gastrointestinal and Liver Physiology, American Physiological Society vol. 311 (5), G981-G987.

DOI 10.1152/ajpgi.00334.2016

01-11-2016

Intracoronary nitrite suppresses the inflammatory response following primary percutaneous coronary intervention
Jones DA, Khambata RS, Andiapen M, Rathod KS, Mathur A, Ahluwalia A
Heart, Bmj vol. 103 (7), 508.2-516.

DOI 10.1136/heartjnl-2016-309748

QMRO

28-09-2016

Temozolomide induces the expression of the glioma Big Potassium (gBK) ion channel, while inhibiting fascin-1 expression: possible targets for glioma therapy
Hoa NT, Ge L, Martini F, Chau V, Ahluwalia A, Kruse CA, Jadus MR
Expert Opinion On Therapeutic Targets, Informa Uk Limited vol. 20 (10), 1155-1167.

DOI 10.1080/14728222.2016.1208172

13-07-2016

Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop
Ahluwalia A, Gladwin M, Coleman GD, Hord N, Howard G, Kim‐Shapiro DB, Lajous M, Larsen FJ et al.
Journal of The American Heart Association, Ovid Technologies (Wolters Kluwer Health) vol. 5 (7)

DOI 10.1161/jaha.116.003402

QMRO

06-07-2016

Preliminary Findings on the Association Between Symptoms of Depression and Adherence to Antiretroviral Therapy in Individuals Born Inside Versus Outside of Canada
Ivanova E, Coroiu A, Ahluwalia A, Alexandrov E, Lafreniere KD
Journal of The Association of Nurses in Aids Care, Ovid Technologies (Wolters Kluwer Health) vol. 27 (4), 512-523.

DOI 10.1016/j.jana.2016.02.005

01-07-2016

Activation of TRPV1 by 12(s)‐HpETE and 20‐HETE Releases CGRP and Protects the Heart Against the Cardiac Dysfunction Caused by LPS
Chen J, Hamers AJP, Finsterbusch M, Thiemermann C, Ahluwalia A

DOI 10.1096/fasebj.30.1_supplement.306.4

01-04-2016

Dietary nitrate suppresses platelet reactivity in Apolipoprotein E Knockout Mice
Filomena F, Khambata R, Ahluwalia A

DOI 10.1096/fasebj.30.1_supplement.1177.19

01-04-2016

Investigation of the influence of sex on cantharidin‐induced inflammation in healthy volunteers
Rathod KS, Siddiqui U, Hartley A, Khambata RS, Ahluwalia A

DOI 10.1096/fasebj.30.1_supplement.716.9

01-04-2016

Dietary Nitrate Supresses Leukocyte Recruitment and Activation in Apolipoprotein E Knockout Mice
Khambata RS, Ghosh SM, Rathod KS, Thevathasan T, Ahluwalia A

DOI 10.1096/fasebj.30.1_supplement.165.2

01-04-2016

In vivo imaging of porcine gastric enteric nervous system using confocal laser endomicroscopy &molecular neuronal probe
Samarasena JB, Ahluwalia A, Shinoura S, Choi KD, Lee JG, Chang KJ, Tarnawski AS
Journal of Gastroenterology and Hepatology, Wiley vol. 31 (4), 802-807.

DOI 10.1111/jgh.13194

01-04-2016

Needs and Supports in Transitional Housing for People Living with HIV/AIDS in Ontario, Canada
Aguinaldo JP, Ahluwalia A, Hambly K, Koornstra J, Rankin B, Roesslein K
Journal of Social Service Research, Informa Uk Limited vol. 42 (3), 352-362.

DOI 10.1080/01488376.2015.1101046

05-02-2016

Dietary Nitrate Lowers Blood Pressure: Epidemiological, Pre-clinical Experimental and Clinical Trial Evidence
Gee LC, Ahluwalia A
Current Hypertension Reports, Springer Science and Business Media Llc vol. 18 (2)

DOI 10.1007/s11906-015-0623-4

QMRO

27-01-2016

Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study
Velmurugan S, Gan JM, Rathod KS, Khambata RS, Ghosh SM, Hartley A, Van Eijl S, Sagi-Kiss V et al.
The American Journal of Clinical Nutrition, Elsevier Bv vol. 103 (1), 25-38.

DOI 10.3945/ajcn.115.116244

QMRO

01-01-2016

A 'green' diet-based approach to cardiovascular health? Is inorganic nitrate the answer?
Rathod KS, Velmurugan S, Ahluwalia A
Molecular Nutrition and Food Research vol. 60 (1), 185-202.

DOI 10.1002/mnfr.201500313

01-01-2016

ACTIVATION OF TRPV1 BY 12(S)-HPETE AND 20-HETE RELEASES CGRP AND PROTECTS THE HEART AGAINST THE CARDIAC DYSFUNCTION CAUSED BY LPS
Chen J, Hamers AJP, Finsterbusch M, Thiemermann C, Ahluwalia A

01-01-2016

Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation
Jandhyala DM, Ahluwalia A, Schimmel JJ, Rogers AB, Leong JM, Thorpe CM
Infection and Immunity, American Society For Microbiology vol. 84 (1), 138-148.

DOI 10.1128/iai.00977-15

01-01-2016

2015

EUS-guided in vivo imaging of the porcine esophageal enteric nervous system by using needle-based confocal laser endomicroscopy
Samarasena JB, Tarnawski AS, Ahluwalia A, Shinoura S, Choi KD, Lee JG, Chang KJ
Gastrointestinal Endoscopy, Elsevier Bv vol. 82 (6), 1116-1120.

DOI 10.1016/j.gie.2015.06.048

01-12-2015

Abstract 10110: Effects of Inorganic Nitrate on Endothelial Dysfunction Induced by Periodontitis
Fernandes D, Khambata R, Ahluwalia A
Circulation, Ovid Technologies (Wolters Kluwer Health) vol. 132 (suppl_3)

DOI 10.1161/circ.132.suppl_3.10110

10-11-2015

A ‘green’ diet‐based approach to cardiovascular health? Is inorganic nitrate the answer?
Rathod KS, Velmurugan S, Ahluwalia A
Molecular Nutrition &Amp; Food Research, Wiley vol. 60 (1), 185-202.

DOI 10.1002/mnfr.201500313

13-09-2015

Erratum

British Journal of Pharmacology, Wiley vol. 172 (18), 4600-4600.

DOI 10.1111/bph.13275

27-08-2015

“Repurposing” of Xanthine Oxidoreductase as a Nitrite Reductase: A New Paradigm for Therapeutic Targeting in Hypertension
Khambata RS, Ghosh SM, Ahluwalia A
Antioxidants &Amp; Redox Signaling, Mary Ann Liebert Inc vol. 23 (4), 340-353.

DOI 10.1089/ars.2015.6254

QMRO

01-08-2015

Erratum to “Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex” [Free Radic. Biol. Med. 65 (2013) 1521–1532]
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.
Free Radical Biology and Medicine, Elsevier Bv vol. 84, 385-385.

DOI 10.1016/j.freeradbiomed.2015.03.015

QMRO

01-07-2015

Experimental design and analysis and their reporting: new guidance for publication in BJP
Curtis MJ, Bond RA, Spina D, Ahluwalia A, Alexander SPA, Giembycz MA, Gilchrist A, Hoyer D et al.
British Journal of Pharmacology, Wiley vol. 172 (14), 3461-3471.

DOI 10.1111/bph.12856

26-06-2015

Erratum: Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex (Free Radical Biology and Medicine (2013) 65 (1521-1532))
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.
Free Radical Biology and Medicine vol. 84

DOI 10.1016/j.freeradbiomed.2015.03.015

QMRO

29-05-2015

Role of Dopamine and D2 Dopamine Receptor in the Pathogenesis of Inflammatory Bowel Disease
Tolstanova G, Deng X, Ahluwalia A, Paunovic B, Prysiazhniuk A, Ostapchenko L, Tarnawski A, Sandor Z et al.
Digestive Diseases and Sciences, Springer Science and Business Media Llc vol. 60 (10), 2963-2975.

DOI 10.1007/s10620-015-3698-5

14-05-2015

Effects of inorganic nitrate and beetroot supplementation on endothelial function: a systematic review and meta-analysis
Lara J, Ashor AW, Oggioni C, Ahluwalia A, Mathers JC, Siervo M
European Journal of Nutrition, Springer Science and Business Media Llc vol. 55 (2), 451-459.

DOI 10.1007/s00394-015-0872-7

13-03-2015

Confocal laser endomicroscopy: A new gold standard for the assessment of mucosal healing in ulcerative colitis
Macé V, Ahluwalia A, Coron E, Le Rhun M, Boureille A, Bossard C, Mosnier J, Matysiak‐Budnik T et al.
Journal of Gastroenterology and Hepatology, Wiley vol. 30 (S1), 85-92.

DOI 10.1111/jgh.12748

01-03-2015

Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients
Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A
Hypertension, Ovid Technologies (Wolters Kluwer Health) vol. 65 (2), 320-327.

DOI 10.1161/hypertensionaha.114.04675

QMRO

01-02-2015

Randomized Phase 2 Trial of Intracoronary Nitrite During Acute Myocardial Infarction
Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, van Eijl S, Webb AJ et al.
Circulation Research, Ovid Technologies (Wolters Kluwer Health) vol. 116 (3), 437-447.

DOI 10.1161/circresaha.116.305082

30-01-2015

Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients A Randomized, Phase 2, Double-Blind, Placebo-Controlled Study
Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A
Hypertension vol. 65 (2), 320-U174.

DOI 10.1161/HYPERTENSIONAHA.114.04675

01-01-2015

Randomized phase 2 trial of intracoronary nitrite during acute myocardial infarction
Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, Van Eijl S, Webb AJ et al.
Circulation Research vol. 116 (3), 437-447.

DOI 10.1161/CIRCRESAHA.116.305082

QMRO

01-01-2015

Acute administration of dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia
Velmurugan S, Ghosh SM, Khambata RS, Van Eijl S, Robertson A, Chowdhury TA, Ahluwalia A

01-01-2015

Effects of Inorganic Nitrate on Endothelial Dysfunction Induced by Periodontitis
Fernandes D, Khambata R, Ahluwalia A

01-01-2015

2014

Angiogenesis in gastric mucosa: An important component of gastric erosion and ulcer healing and its impairment in aging
Tarnawski AS, Ahluwalia A, Jones MK
Journal of Gastroenterology and Hepatology, Wiley vol. 29 (S4), 112-123.

DOI 10.1111/jgh.12734

01-12-2014

Dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia
Velmurugan S, Ghosh S, Khambata R, Van Eijl S, Robertson A, Chowdhury T, Ahluwalia A
Nitric Oxide, Elsevier Bv vol. 42, 147-147.

DOI 10.1016/j.niox.2014.09.141

01-11-2014

Xanthine oxidoreductase in atherosclerotic mice: Determination of expression and nitrite reductase activity
Rathod K, Ghosh S, Khambata R, Ahluwalia A
Nitric Oxide, Elsevier Bv vol. 42, 139-139.

DOI 10.1016/j.niox.2014.09.119

01-11-2014

The safety and efficacy of intra-coronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): A single centre, randomised, double-blind controlled trial
Jones DA, Pellaton C, Velmurugan S, Andiapen M, Antoniou S, Van Eijl S, Westwood MA, Webb AJ et al.
Nitric Oxide, Elsevier Bv vol. 42, 127-128.

DOI 10.1016/j.niox.2014.09.087

01-11-2014

Novel mechanisms and signaling pathways of esophageal ulcer healing: the role of prostaglandin EP2 receptors, cAMP, and pCREB
Ahluwalia A, Baatar D, Jones MK, Tarnawski AS
American Journal of Physiology-Gastrointestinal and Liver Physiology, American Physiological Society vol. 307 (6), G602-G610.

DOI 10.1152/ajpgi.00177.2014

15-09-2014

Endothelial C-type natriuretic peptide maintains vascular homeostasis
Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ et al.
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 124 (9), 4039-4051.

DOI 10.1172/jci74281

QMRO

08-08-2014

Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health
Kapil V, Weitzberg E, Lundberg JO, Ahluwalia A
Nitric Oxide, Elsevier Bv vol. 38, 45-57.

DOI 10.1016/j.niox.2014.03.162

01-04-2014

Key role of endothelial importin-α in VEGF expression and gastric angiogenesis: novel insight into aging gastropathy
Ahluwalia A, Jones MK, Tarnawski AS
American Journal of Physiology-Gastrointestinal and Liver Physiology, American Physiological Society vol. 306 (4), G338-G345.

DOI 10.1152/ajpgi.00382.2013

15-02-2014

VEGF and Colon Cancer Growth Beyond Angiogenesis: Does VEGF Directly Mediate Colon Cancer Growth Via a Non-angiogenic Mechanism?
Ahluwalia A, Jones M, Matysiak-Budnik T, Tarnawski A
Current Pharmaceutical Design, Bentham Science Publishers Ltd. vol. 20 (7), 1041-1044.

DOI 10.2174/1381612819999131218175905

01-02-2014

STAT3 and Importins Are Novel Mediators of Early Molecular and Cellular Responses in Experimental Duodenal Ulceration
Khomenko T, Deng X, Ahluwalia A, Tarnawski A, Patel KN, Sandor Z, Szabo S
Digestive Diseases and Sciences, Springer Science and Business Media Llc vol. 59 (2), 297-306.

DOI 10.1007/s10620-013-2807-6

03-01-2014

Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health
Kapil V, Weitzberg E, Lundberg JO, Ahluwalia A
Nitric Oxide-Biology and Chemistry vol. 38, 45-57.

DOI 10.1016/j.niox.2014.03.162

01-01-2014

Dietary nitrate improves endothelial function, vascular stiffness and modifies platelet markers of atherogenesis in hypercholesterolemia
Velmurugan S, Ghosh SM, Khambata RS, Robertson AC, Van Eijl TJA, Chowdhury TA, Ahluwalia A

01-01-2014

The safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): a single centre, randomised, double-blind controlled trial
Jones DA, Pellaton C, Velmurugan S, Andiapen M, Antoniou S, Van Eijl S, Westwood M, Parmar MK et al.

01-01-2014

DIETARY INORGANIC NITRATE REDUCES INFLAMMATORY CELL RECRUITMENT IN MICE
Ghosh S, Khambata R, Ahluwalia A

01-01-2014

Increased susceptibility of aging gastric mucosa to injury: The mechanisms and clinical implications
Tarnawski AS
World Journal of Gastroenterology, Baishideng Publishing Group Inc. vol. 20 (16), 4467-4467.

DOI 10.3748/wjg.v20.i16.4467

01-01-2014

2013

Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al.
Free Radical Biology and Medicine, Elsevier Bv vol. 65, 1521-1532.

DOI 10.1016/j.freeradbiomed.2013.06.031

01-12-2013

Characterisation of the “Endothelin-Like Domain Peptide” (ELDP) co-synthesised with Endothelin-1 from the EDN1 gene
Yuzugulen J, Wood EG, Villar IC, Douthwaite JA, Patel NSAINS, Jegard J, Montoya A, Cutillas P et al.
Life Sciences, Elsevier Bv vol. 93 (25-26), e2-e2.

DOI 10.1016/j.lfs.2013.12.037

01-12-2013

An imbalance between VEGF and endostatin underlies impaired angiogenesis in gastric mucosa of aging rats
Ahluwalia A, Jones MK, Deng X, Sandor Z, Szabo S, Tarnawski AS
American Journal of Physiology-Gastrointestinal and Liver Physiology, American Physiological Society vol. 305 (4), G325-G332.

DOI 10.1152/ajpgi.00127.2013

15-08-2013

Activation of Neuronal Transient Receptor Potential Vanilloid 1 Channel Underlies 20-Hydroxyeicosatetraenoic Acid–Induced Vasoactivity
Bubb KJ, Wen H, Panayiotou CM, Finsterbusch M, Khan FJ, Chan MV, Priestley JV, Baker MD et al.
Hypertension, Ovid Technologies (Wolters Kluwer Health) vol. 62 (2), 426-433.

DOI 10.1161/hypertensionaha.111.00942

01-08-2013

Aberrant, ectopic expression of VEGF and VEGF receptors 1 and 2 in malignant colonic epithelial cells. Implications for these cells growth via an autocrine mechanism
Ahluwalia A, Jones MK, Szabo S, Tarnawski AS
Biochemical and Biophysical Research Communications, Elsevier Bv vol. 437 (4), 515-520.

DOI 10.1016/j.bbrc.2013.06.096

01-08-2013

Enhanced Vasodilator Activity of Nitrite in Hypertension
Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S et al.
Hypertension, Ovid Technologies (Wolters Kluwer Health) vol. 61 (5), 1091-1102.

DOI 10.1161/hypertensionaha.111.00933

01-05-2013

P22
Jones DA, Khambata RS, Mathur A, Ahluwalia A

DOI 10.1016/j.niox.2013.02.024

01-04-2013

P28
Ghosh SM, Kapil V, Bubb K, Fuentes-Calvo I, Ahluwalia A

DOI 10.1016/j.niox.2013.02.030

01-04-2013

Kinin B1 receptor regulates inflammatory cell recruitment during low laminar shear stress
Martin K, Perretti M, Ahluwalia A

DOI 10.1096/fasebj.27.1_supplement.646.4

01-04-2013

CXCL5 limits macrophage foam cell formation in atherosclerosis
Rousselle A, Qadri F, Leukel L, Yilmaz R, Fontaine J-F, Sihn G, Bader M, Ahluwalia A et al.
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 123 (3), 1343-1347.

DOI 10.1172/jci66580

08-02-2013

Physiological role for nitrate-reducing oral bacteria in blood pressure control
Kapil V, Haydar SMA, Pearl V, Lundberg JO, Weitzberg E, Ahluwalia A
Free Radical Biology and Medicine, Elsevier Bv vol. 55, 93-100.

DOI 10.1016/j.freeradbiomed.2012.11.013

01-02-2013

Letter by Ahluwalia and Hobbs Regarding Article, “Nitrate-Nitrite-Nitric Oxide Pathway in Pulmonary Arterial Hypertension Therapeutics”
Ahluwalia A, Hobbs AJ
Circulation, Ovid Technologies (Wolters Kluwer Health) vol. 127 (2)

DOI 10.1161/circulationaha.112.118356

15-01-2013

The safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): study protocol of a randomised controlled trial
Jones DA, Andiapen M, Van-Eijl TJA, Webb AJ, Antoniou S, Schilling RJ, Ahluwalia A, Mathur A
Bmj Open, Bmj vol. 3 (4), e002813-e002813.

DOI 10.1136/bmjopen-2013-002813

QMRO

01-01-2013

DOI 10.1016/j.freeradbiomed.2013.06.031

01-01-2013

2012

Abstract 18898: Characterization of Proendothelin-1 Derived Peptides Identifies a Co-secreted Modulator of ET-1 Vasoconstriction, and Provides Insights for Biomarker Measurements
Yuzugulen J, Wood EG, Douthwaite JA, Villar IC, Patel NS, Jegard J, Montoya A, Cutillas P et al.
Circulation, Ovid Technologies (Wolters Kluwer Health) vol. 126 (suppl_21)

DOI 10.1161/circ.126.suppl_21.a18898

20-11-2012

Distinct endothelial pathways underlie sexual dimorphism in vascular auto‐regulation
Chan MV, Bubb KJ, Noyce A, Villar IC, Duchene J, Hobbs AJ, Scotland RS, Ahluwalia A
British Journal of Pharmacology, Wiley vol. 167 (4), 805-817.

DOI 10.1111/j.1476-5381.2012.02012.x

25-09-2012

Sexual dimorphism in rodent models of hypertension and atherosclerosis
Bubb KJ, Khambata RS, Ahluwalia A
British Journal of Pharmacology, Wiley vol. 167 (2), 298-312.

DOI 10.1111/j.1476-5381.2012.02036.x

22-08-2012

Nitrite superfusion reduces leukocyte–endothelial interactions in the mouse cremaster model
Khambata R, Ghosh S, Ahluwalia A

DOI 10.1016/j.niox.2012.04.055

01-07-2012

Nitrite induced-hypotension is enhanced in hypertension: Role for xanthine oxidoreductase
Fuentes-Calvo I, Bubb K, Ghosh S, Ahluwalia A

DOI 10.1016/j.niox.2012.04.110

01-07-2012

Mechanisms underlying nitrite reduction in hypertension: Role for erythrocyte xanthine oxidoreductase
Ghosh S, Kapil V, Bubb K, Fuentes I, Ahluwalia A

DOI 10.1016/j.niox.2012.04.109

01-07-2012

Inorganic nitrate supplementation attenuates platelet reactivity in healthy male volunteers
Velmurugan S, Pearl V, Davies S, Bahra M, Ghosh S, Kapil V, Ahluwalia A

DOI 10.1016/j.niox.2012.04.099

01-07-2012

Dietary Nitrate Ameliorates Pulmonary Hypertension
Baliga RS, Milsom AB, Ghosh SM, Trinder SL, MacAllister RJ, Ahluwalia A, Hobbs AJ
Circulation, Ovid Technologies (Wolters Kluwer Health) vol. 125 (23), 2922-2932.

DOI 10.1161/circulationaha.112.100586

12-06-2012

Inorganic nitrate ingestion improves vascular compliance but does not alter flow-mediated dilatation in healthy volunteers
Bahra M, Kapil V, Pearl V, Ghosh S, Ahluwalia A
Nitric Oxide, Elsevier Bv vol. 26 (4), 197-202.

DOI 10.1016/j.niox.2012.01.004

01-05-2012

Dietary Nitrate: A Novel Therapy For Pulmonary Hypertension
Baliga RS, Milsom AB, Trinder SL, Ghosh S, MacAllister RJ, Ahluwalia A, Hobbs AJ
American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California.

DOI 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3413

01-05-2012

20-Hydroxyeicosatetraenoic Acid (20-HETE) Is a Novel Activator of Transient Receptor Potential Vanilloid 1 (TRPV1) Channel
Wen H, Östman J, Bubb KJ, Panayiotou C, Priestley JV, Baker MD, Ahluwalia A
Journal of Biological Chemistry, Elsevier Bv vol. 287 (17), 13868-13876.

DOI 10.1074/jbc.m111.334896

01-04-2012

20-HETE-induced activation of TRPV1: a novel pathway influencing blood pressure and coronary resistance
Bubb KJ, Ahluwalia A

01-01-2012

Inorganic nitrate ingestion decreases blood pressure and improves vascular compliance in healthy volunteers
Bahra M, Kapil V, Pearl V, Ghosh S, Ahluwalia A

01-01-2012

Inorganic Nitrate Attenuates Platelet Reactivity in Healthy Males but not Females: Role of the Erythrocyte and Cyclic GMP
Velmurugan S, Pearl V, Ghosh SM, Davies S, Khambata RS, van Eijl S, Kapil V, Ahluwalia A
Circulation vol. 126 (21)
01-01-2012

Accelerated Atherogenesis and Diminished Vascular Integrity in Mice Lacking Endothelial C-Type Natriuretic Peptide
Moyes AJ, Khambata RS, Ahluwalia A, Hobbs AJ
Circulation vol. 126 (21)
01-01-2012

Characterization of Proendothelin-1 Derived Peptides Identifies a Co-secreted Modulator of ET-1 Vasoconstriction, and Provides Insights for Biomarker Measurements
Yuzugulen J, Wood EG, Douthwaite JA, Villar IC, Patel NS, Jegard J, Montoya A, Cutillas P et al.
Circulation vol. 126 (21)
01-01-2012

Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib
Stone SM, Thorpe CM, Ahluwalia A, Rogers AB, Obata F, Vozenilek A, Kolling GL, Kane AV et al.
Frontiers in Cellular and Infection Microbiology, Frontiers Media Sa vol. 2

DOI 10.3389/fcimb.2012.00135

01-01-2012

2011

Schwann cell‐specific JAM‐C‐deficient mice reveal novel expression and functions for JAM‐C in peripheral nerves
Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Carro UD, Zambroni D, Brain SD et al.
The Faseb Journal, Wiley vol. 26 (3), 1064-1076.

DOI 10.1096/fj.11-196220

16-11-2011

Kinins

, De Gruyter

DOI 10.1515/9783110252354

16-11-2011

16 Kallikrein-kinin system in infl ammation
Duchene J, Ahluwalia A
In Kinins, De Gruyter 261-272.

DOI 10.1515/9783110252354.261

16-11-2011

Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats
Paunovic B, Deng X, Khomenko T, Ahluwalia A, Tolstanova G, Tarnawski A, Szabo S, Sandor Z
The Journal of Pharmacology and Experimental Therapeutics, Elsevier Bv vol. 339 (2), 430-437.

DOI 10.1124/jpet.111.183665

01-11-2011

Gastric mucosal injury activates bFGF gene expression and triggers preferential translation of high molecular weight bFGF isoforms through CUG-initiated, non-canonical codons
Florkiewicz RZ, Ahluwalia A, Sandor Z, Szabo S, Tarnawski AS
Biochemical and Biophysical Research Communications, Elsevier Bv vol. 409 (3), 494-499.

DOI 10.1016/j.bbrc.2011.05.033

01-06-2011

Suppression of Endothelial P-Selectin Expression Contributes to Reduced Cell Trafficking in Females An Effect Independent of NO and Prostacyclin
Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ et al.
Arterioscl Throm Vas vol. 31 (5), 1075-1083.

DOI 10.1161/ATVBAHA.111.223545

01-05-2011

Interruption of the entero-salivary metabolism of nitrate to nitrite increases blood pressure in healthy volunteers
Kapil V, Syed M, Pearl V, Allaker R, Ahluwalia A

DOI 10.1016/j.niox.2011.03.282

01-05-2011

P54. Dietary nitrate attenuates platelet reactivity: Role of the erythrocyte and influence of sex
Velmurugan S, Kapil V, McKnight AHO, Aboud Z, Davies S, Milsom AB, Pearl V, Liverani E et al.

DOI 10.1016/j.niox.2011.03.285

01-05-2011

Inequalities in Determinants of Health Among Aboriginal and Caucasian Persons Living With HIV/AIDS in Ontario: Results From the Positive Spaces, Healthy Places Study
Monette LE, Rourke SB, Gibson K, Bekele TM, Tucker R, Greene S, Sobota M, Koornstra J et al.
Canadian Journal of Public Health, Springer Science and Business Media Llc vol. 102 (3), 215-219.

DOI 10.1007/bf03404900

01-05-2011

Response to Inorganic Nitrate for Blood Pressure Lowering?
Kapil V, Benjamin N, Hobbs A, Ahluwalia A
Hypertension, Ovid Technologies (Wolters Kluwer Health) vol. 57 (2)

DOI 10.1161/hypertensionaha.110.164814

01-02-2011

Social determinants of health associated with hepatitis C co-infection among people living with HIV: results from the Positive Spaces, Healthy Places study.
Rourke SB, Sobota M, Tucker R, Bekele T, Gibson K, Greene S, Price C, Koornstra JJJ et al.
Open Medicine : a Peer-Reviewed, Independent, Open-Access Journal vol. 5 (3), e120-e131.
01-01-2011

2010

Inorganic nitrate and the cardiovascular system
Kapil V, Webb AJ, Ahluwalia A
Heart vol. 96 (21), 1703-1709.

DOI 10.1136/hrt.2009.180372

01-11-2010

Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice
Yamashiro K, Milsom AB, Duchene J, Panayiotou C, Urabe T, Hattori N, Ahluwalia A
J Cerebr Blood F Met vol. 30 (8), 1494-1503.

DOI 10.1038/jcbfm.2010.34

01-08-2010

Inorganic Nitrate Supplementation Lowers Blood Pressure in Humans Role for Nitrite-Derived NO
Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, Arghandawi S, Pearl V et al.
Hypertension vol. 56 (2), 274-U174.

DOI 10.1161/HYPERTENSIONAHA.110.153536

01-08-2010

PTEN silencing reverses aging-related impairment of angiogenesis in microvascular endothelial cells
Tarnawski AS, Pai R, Tanigawa T, Matysiak-Budnik T, Ahluwalia A
Biochemical and Biophysical Research Communications, Elsevier Bv vol. 394 (2), 291-296.

DOI 10.1016/j.bbrc.2010.02.161

01-04-2010

Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia–reperfusion injury in mice
Milsom AB, Patel NSA, Mazzon E, Tripatara P, Storey A, Mota-Filipe H, Sepodes B, Webb AJ et al.

DOI 10.1016/j.niox.2009.10.010

01-02-2010

A Role of Matrix Metalloproteinase-8 in Atherosclerosis (vol 105, pg 921, 2009)
Laxton RC, Hu Y, Duchene J, Zhang F, Zhang Z, Leung KY, Xiao Q, Scotland RS et al.
Circ Res vol. 106 (1), E1-E1.

DOI 10.1161/RES.0b013e3181cdee32

08-01-2010

Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice
Milsom AB, Patel NSA, Mazzon E, Tripatara P, Storey A, Mota-Filipe H, Sepodes B, Webb AJ et al.
Nitric Oxide-Biology and Chemistry vol. 22 (2), 141-148.

DOI 10.1016/j.niox.2009.10.010

01-01-2010

Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System
Webb A, Ahluwalia A
In Nitric Oxide, Elsevier 555-586.

DOI 10.1016/b978-0-12-373866-0.00017-4

01-01-2010

Chapter 17 Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System
Webb A, Ahluwalia A
In Nitric Oxide, Elsevier 555-586.

DOI 10.1016/b978-0-12-373866-0.00017-4

01-01-2010

Oral inorganic nitrate lowers blood pressure in healthy male, but not female, volunteers, via bioconversion to nitrite
Kapil V, Maleki-Toyserkani S, Rehman F, Arghandawi S, Pearl V, Milsom A, Benjamin N, Hobbs A et al.

01-01-2010

2009

Nitrate and nitrite in biology, nutrition and therapeutics
Lundberg JO, Gladwin MT, Ahluwalia A, Benjamin N, Bryan NS, Butler A, Cabrales P, Fago A et al.
Nature Chemical Biology, Springer Science and Business Media Llc vol. 5 (12), 865-869.

DOI 10.1038/nchembio.260

01-12-2009

Laminar Shear Stress Regulates Endothelial Kinin B1 Receptor Expression and Function Potential Implication in Atherogenesis
Duchene J, Cayla C, Vessillier S, Scotland R, Yamashiro K, Lecomte F, Syed I, Vo P et al.
Arterioscl Throm Vas vol. 29 (11), 1757-1763.

DOI 10.1161/ATVBAHA.109.191775

01-11-2009

A Role of Matrix Metalloproteinase-8 in Atherosclerosis
Laxton RC, Hu YH, Duchene J, Zhang F, Zhang ZY, Leung KY, Xiao QZ, Scotland RS et al.
Circ Res vol. 105 (9), 921-U231.

DOI 10.1161/CIRCRESAHA.109.200279

23-10-2009

Between skepticism and empowerment: the experiences of peer research assistants in HIV/AIDS, housing and homelessness community‐based research
Greene S, Ahluwalia A, Watson J, Tucker R, Rourke SB, Koornstra J, Sobota M, Monette L et al.
International Journal of Social Research Methodology, Informa Uk Limited vol. 12 (4), 361-373.

DOI 10.1080/13645570802553780

01-10-2009

“Under My Umbrella”: The housing experiences of HIV positive parents who live with and care for their children in Ontario
Greene S, Tucker R, Rourke SB, Monette L, Koornstra J, Sobota M, Byers S, Hwang S et al.
Archives of Women's Mental Health, Springer Science and Business Media Llc vol. 13 (3), 223-232.

DOI 10.1007/s00737-009-0090-5

16-09-2009

Design and development of novel non‐peptide agonists at natriuretic peptide receptor‐C
Hobbs AJ, Gane P, Lumsden N, Nobles M, Rebstock A, Simone M, Villar I, Worthington R et al.
The Faseb Journal, Wiley vol. 23 (S1)

DOI 10.1096/fasebj.23.1_supplement.756.8

01-04-2009

The kinin B-1 receptor and inflammation: new therapeutic target for cardiovascular disease
Duchene J, Ahluwalia A
Curr Opin Pharmacol vol. 9 (2), 125-131.

DOI 10.1016/j.coph.2008.11.011

01-04-2009

Neutralizing Anti-Vascular Endothelial Growth Factor (VEGF) Antibody Reduces Severity of Experimental Ulcerative Colitis in Rats: Direct Evidence for the Pathogenic Role of VEGF
Tolstanova G, Khomenko T, Deng X, Chen L, Tarnawski A, Ahluwalia A, Szabo S, Sandor Z
The Journal of Pharmacology and Experimental Therapeutics, Elsevier Bv vol. 328 (3), 749-757.

DOI 10.1124/jpet.108.145128

01-03-2009

Oral inorganic nitrate lowers blood pressure and protects against endothelial ischaemia-reperfusion injury in humans
Kapil V, Okorie M, Akram F, Rehman F, Milsom A, Arghandawi S, Pearl V, Deanfield J et al.

01-01-2009

BLOOD PRESSURE LOWERING EFFECTS OF ORAL INORGANIC NITRATE VIA BIOCONVERSION TO NITRITE
Kapil V, Rehman F, Arghandawi S, Milsom A, Benjamin N, Hobbs A, MacAllister R, Webb A et al.
Basic & Clinical Pharmacology & Toxicology vol. 105, 31-31.
01-01-2009

THERAPEUTIC TARGETTING OF ATHEROSCLEROTIC PLAQUES WITH LATENT INTERLEUKIN-4
Vessillier S, Duchene J, Vojnovic I, Cipollone F, Mezzetti A, White S, Ahluwalia A, Bishop-Bailey D et al.

DOI 10.1136/hrt.2009.178129h

01-01-2009

Erthrocyte and endothelial nitrite in hypoxia: role for NOS and XOR
Ahluwalia A

01-01-2009

ORAL INORGANIC NITRATE PROTECTS AGAINST ENDOTHELIAL ISCHAEMIA-REPERFUSION INJURY IN HUMANS
Okorie M, Akram F, Loukogeorgakis S, Webb A, Deanfield J, Benjamin N, Hobbs A, MacAllister R et al.
Basic & Clinical Pharmacology & Toxicology vol. 105, 26-26.
01-01-2009

Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System
Webb A, Ahluwalia A
In Nitric Oxide Biology and Pathobiology 555-586.

DOI 10.1016/B978-0-12-373866-0.00017-4

01-01-2009

2008

Mechanisms Underlying Erythrocyte and Endothelial Nitrite Reduction to Nitric Oxide in Hypoxia Role for Xanthine Oxidoreductase and Endothelial Nitric Oxide Synthase
Webb AJ, Milsom AB, Rathod KS, Chu WL, Qureshi S, Lovell MJ, Lecomte FMJ, Perrett D et al.
Circ Res vol. 103 (9), 957-U114.

DOI 10.1161/CIRCRESAHA.108.175810

24-10-2008

Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy
Klein J, Gonzalez J, Duchene J, Esposito L, Pradere JP, Neau E, Delage C, Calise D et al.
The Faseb Journal, Wiley vol. 23 (1), 134-142.

DOI 10.1096/fj.08-115600

22-09-2008

ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression
Jandhyala DM, Ahluwalia A, Obrig T, Thorpe CM
Cellular Microbiology, Hindawi Limited vol. 10 (7), 1468-1477.

DOI 10.1111/j.1462-5822.2008.01139.x

01-07-2008

Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor
Villar IC, Hobbs AJ, Ahluwalia A
Journal of Endocrinology, Bioscientifica vol. 197 (3), 447-462.

DOI 10.1677/joe-08-0070

01-06-2008

Endothelium‐derived hyperpolarising factor (EDHF) underlies sex‐differences in the pressure‐induced myogenic response
Chan M, Villar I, Scotland R, Ahluwalia A

DOI 10.1096/fasebj.22.1_supplement.719.4

01-03-2008

Acute blood pressure lowering and vasoprotective effects of dietary nitrate
Webb A, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P et al.
The Faseb Journal, Wiley vol. 22 (S1)

DOI 10.1096/fasebj.22.1_supplement.737.30

01-03-2008

Opposing effects of the kinin B₁ and B₂ receptors in LPS‐induced hypotension.
Duchene J, Francis S, Lecomte F, Stidwill R, Singer M, Cayla C, Bader M, Perretti M et al.

DOI 10.1096/fasebj.22.1_supplement.912.26

01-03-2008

Selective regulation of chemokine CXCL6 by estrogen receptorβ (ERβ)
Scotland RS, Roy B, Duchene J, Ahluwalia A

DOI 10.1096/fasebj.22.1_supplement.718.3

01-03-2008

Acute Blood Pressure Lowering, Vasoprotective, and Antiplatelet Properties of Dietary Nitrate via Bioconversion to Nitrite
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P et al.
Hypertension, Ovid Technologies (Wolters Kluwer Health) vol. 51 (3), 784-790.

DOI 10.1161/hypertensionaha.107.103523

01-03-2008

The enterosalivary bioconversion of nitrate to nitrite underlies the blood pressure (BP) lowering and anti-platelet effects of a dietary nitrate load
Aboud Z, Misra S, Warner T, Miall P, Benjamin N, Hobbs A, Webb A, Ahluwalia A

01-01-2008

Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite.
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P et al.
Hypertension, American Heart Association vol. 51, 784-790.

DOI 10.1161/HYPERTENSIONAHA.107.103523

01-01-2008

Stabilisation of atherosclerotic plaques: The latent targeting cytokines strategy
Vessillier S, Duchene J, Vojnovic I, Ahluwalia A, Bishop-Bailey D, Chernajovsky Y, Warner TD

01-01-2008

Nitric oxide-induced relaxation in female resistance arteries is endothelium-dependent
Chan MV, Hobbs AJ, Scotland RS, Ahluwalia A

01-01-2008

P38. Endothelial nitric oxide synthase acts as a nitrite reductase in human endothelial cells
Milsom AB, Hobbs AJ, Ahluwalia A

DOI 10.1016/j.niox.2008.06.134

01-01-2008

O33. Mechanisms of nitrite reduction in the cardiovascular system
Ahluwalia A

DOI 10.1016/j.niox.2008.06.034

01-01-2008

2007

Aging Gastropathy—Novel Mechanisms: Hypoxia, Up-regulation of Multifunctional Phosphatase PTEN, and Proapoptotic Factors
Tarnawski A, Pai R, Deng X, Ahluwalia A, Khomenko T, Tanigawa T, Akahoshi T, Sandor Z et al.
Gastroenterology, Elsevier Bv vol. 133 (6), 1938-1947.e1.

DOI 10.1053/j.gastro.2007.08.037

01-12-2007

A novel inflammatory pathway recruitment: Role for the kinin chemokine CXCL5
Duchene J, Lecomte F, Ahmed S, Cayla C, Pesquero J, Bader M, Perretti M, Ahluwalia A
J Immunol vol. 179 (7), 4849-4856.

DOI 10.4049/jimmunol.179.7.4849

01-10-2007

12-Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1
Sexton A, McDonald M, Cayla C, Thiemermann C, Ahluwalia A
Faseb J vol. 21 (11), 2695-2703.

DOI 10.1096/fj.06-7828com

01-09-2007

Definitive role for natriuretic peptide receptor-C in mediating the vasorelaxant activity of C-type natriuretic peptide and endothelium-derived hyperpolarising factor
VILLAR I, PANAYIOTOU C, SHERAZ A, MADHANI M, SCOTLAND R, NOBLES M, KEMPHARPER B, AHLUWALIA A et al.
Cardiovascular Research, Oxford University Press (Oup) vol. 74 (3), 515-525.

DOI 10.1016/j.cardiores.2007.02.032

01-06-2007

Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: Role for xanthine oxidoreductase
Tripatara P, Patel NSA, Webb A, Rathod K, Lecomte FMJ, Mazzon E, Cuzzocrea S, Yaqoob MM et al.
J Am Soc Nephrol vol. 18 (2), 570-580.

DOI 10.1681/ASN.2006050450

01-02-2007

Acute blood pressure lowering and vasoprotective effects of beetroot juice: relationship to nitrite derived from dietary nitrate
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Rashid R, Deanfield J, Benjamin N, Macallister R et al.

01-01-2007

Acute blood pressure (BP) lowering and vasoprotective effects of beetroot juice: relationship to nitrite derived from dietary nitrate
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Rashid R, Deanfield J, Benjamin N, MacAllister R et al.

01-01-2007

2006

Nitrite Is Reduced to Nitric Oxide by Xanthine Oxidoreductase and Nitric Oxide Synthase in the Erythrocyte Membrane in Hypoxemia.
Rathod KS, Webb AJ, Lovell MJ, Lecomte F, Ahluwalia A

DOI 10.1182/blood.v108.11.1560.1560

16-11-2006

Novel aspects of endothelium-dependent regulation of vascular tone
Villar IC, Francis S, Webb A, Hobbs AJ, Ahluwalia A
Kidney International, Elsevier Bv vol. 70 (5), 840-853.

DOI 10.1038/sj.ki.5001680

01-09-2006

Identification of an endogenous cardioprotective pathway involving 12‐lipoxygenase (12‐LOX), C‐fibers and the non‐selective cation channel TRPV1
Goddard A, McDonald M, Thiemermann C, Ahluwalia A

DOI 10.1096/fasebj.20.4.a230

01-03-2006

INFLAMMATORY CHEMOKINE CXCL5 EXPRESSION BY ENDOTHELIAL CELLS IS DEPENDENT UPON KININ B1 RECEPTOR ACTIVATION
Duchene J, Lecomte F, Perretti M, Ahluwalia A

DOI 10.1096/fasebj.20.4.a702-c

01-03-2006

Gender‐differences in leukocyte activation in vivo: role of endothelium‐derived mediators
Scotland RS, Duchene J, Hobbs A, Ahluwalia A

DOI 10.1096/fasebj.20.5.a1193-b

01-03-2006

Distinct pathways regulate endothelium derived hyperpolarising factor-mediated responses in rat mesenteric arteries
Villar IC, Ahluwalia A, Hobbs AJ
Acta Pharmacologica Sinica vol. 27 (9), 1276-1276.
01-01-2006

2005

C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression
Scotland RS, Cohen M, Foster P, Lovell M, Mathur A, Ahluwalia A, Hobbs AJ
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 102 (40), 14452-14457.

DOI 10.1073/pnas.0504961102

22-09-2005

Endothelium-derived C-type natriuretic peptide: more than just a hyperpolarizing factor
Ahluwalia A, Hobbs AJ
Trends in Pharmacological Sciences, Elsevier Bv vol. 26 (3), 162-167.

DOI 10.1016/j.tips.2005.01.005

01-03-2005

Autoregulatory role of endothelium-derived nitric oxide (NO) on lipopolysaccharide-induced vascular inducible NO synthase expression and function
Vo PA, Lad B, Tomlinson JAP, Francis S, Ahluwalia A
J Biol Chem vol. 280 (8), 7236-7243.

DOI 10.1074/jbc.M411317200

25-02-2005

Investigation of Vascular Responses in Endothelial Nitric Oxide Synthase/Cyclooxygenase-1 Double-Knockout Mice
Scotland RS, Madhani M, Chauhan S, Moncada S, Andresen J, Nilsson H, Hobbs AJ, Ahluwalia A
Circulation, Ovid Technologies (Wolters Kluwer Health) vol. 111 (6), 796-803.

DOI 10.1161/01.cir.0000155238.70797.4e

15-02-2005

C-type natriuretic peptide in vascular physiology and disease
Scotland RS, Ahluwalia A, Hobbs AJ
Pharmacology &Amp; Therapeutics, Elsevier Bv vol. 105 (2), 85-93.

DOI 10.1016/j.pharmthera.2004.08.011

01-02-2005

Investigation of Vascular Responses in Endothelial Nitric Oxide Synthase/Cyclooxygenase-1 Double-Knockout Mice: Key Role for Endothelium-Derived Hyperpolarizing Factor in the Regulation of Blood Pressure in Vivo
Ahluwalia A, SCOTLAND RS, Andersen J, Chauhan S, Moncada S, Nilsson H, Hobbs AJ, Madhani M
Circulation vol. 111 (6), 796-803.

DOI 10.1161/01.CIR.0000155238.70797.4E

01-02-2005

Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo.
AHLUWALIA A, Scotland RS, Hobbs AJ, Moncada S, Chauhan S, Andresen J, Nilsson H, Madhani M
Circulation vol. 111 (6), 796-803.
01-01-2005

The natriuretic peptide receptor-C antagonist, M372049, blocks C-type natriuretic peptide and endothelium-derived hyperpolarizing factor-induced relaxation of resistance arteries
Ahluwalia A, Villar I, Scotland RS, Hobbs A

01-01-2005

role of endothelium-derived nitric oxide (NO) on Lipopolysaccharide-induced vascular inducible NO synthase expression and function.
AHLUWALIA A, Francis S, Tomlinson JA, Lad B, Vo PA
J Biol Chem vol. 25280 (8), 7236-7243.
01-01-2005

Xanthine oxidase activity provides an alternative source of no during ischaemia from inorganic nitrite in rat blood vessels
Webb A, Qureshi S, Benjamin N, Perrett D, Ahluwalia A
British Journal of Clinical Pharmacology vol. 59 (5), 631-632.
01-01-2005

C-type natriuretic peptide inhibits leukocyte recruitment and platelet aggregation
AHLUWALIA A, Mathur A, Lovell M, Hobbs AJ, Cohen M, Scotland RS
Pnas vol. 102 (40), 14452-14457.
01-01-2005

Chemokine involvement in kinin B1 receptor-mediated leukocyte recruitment
Duchene J, Perretti M, Ahluwalia A

01-01-2005

2004

Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation - A novel mechanism involved in myogenic constriction
Scotland RS, Chauhan S, Davis C, De Felipe C, Hunt S, Kabir J, Kotsonis P, Oh U et al.
Circ Res vol. 95 (10), 1027-1034.

DOI 10.1161/01.RES.0000148633.93110.24

12-11-2004

Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction
AHLUWALIA A, Oh U, Kabir J, De Felipe C, Chauhan S, Scotland RS, Davis C, Hunt S et al.
Circ Res vol. 95 (10), 1027-1034.

DOI 10.1161/01.RES.0000148633.93110.24

01-11-2004

C-type natriuretic peptide: new candidate for endothelium-derived hyperpolarising factor
Chauhan SD, Hobbs AJ, Ahluwalia A
Int J Biochem Cell B vol. 36 (10), 1878-1881.

DOI 10.1016/j.biocel.2003.09.009

01-10-2004

Natriuretic Peptide Receptor-C Regulates Coronary Blood Flow and Prevents Myocardial Ischemia/Reperfusion Injury
Hobbs A, Foster P, Prescott C, Scotland R, Ahluwalia A
Circulation, Ovid Technologies (Wolters Kluwer Health) vol. 110 (10), 1231-1235.

DOI 10.1161/01.cir.0000141802.29945.34

07-09-2004

Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia–reperfusion damage
Webb A, Bond R, McLean P, Uppal R, Benjamin N, Ahluwalia A
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 101 (37), 13683-13688.

DOI 10.1073/pnas.0402927101

03-09-2004

HUMAN AND RAT MYOCARDIUM REDUCES NITRITE TO NITRIC OXIDE UNDER ISCHAEMIC CONDITIONS, IN A PROCESS DEPENDENT ON XANTHINE OXIDOREDUCTASE
Webb AJ, Bond R, Uppal R, Benjamin N, Ahluwalia A

DOI 10.1097/00004872-200406002-00054

01-06-2004

ESSENTIAL ROLE FOR ENDOTHELIUM-DERIVED NO IN LIPOPOLYSACCHARIDE-INDUCED INOS EXPRESSION AND FUNCTION
Vo PA, Ladd B, Tomlinson JAP, Ahluwalia A

DOI 10.1097/00024382-200403001-00381

01-03-2004

Vascular actions of natriuretic peptides - Cyclic GMP-dependent and -independent mechanisms
Ahluwalia A, MacAllister RJ, Hobbs AJ
Basic Res Cardiol vol. 99 (2), 83-89.

DOI 10.1007/s00395-004-0459-6

01-03-2004

DICHOTOMOUS ROLE OF THE ENDOTHELIUM IN LPS-INDUCED ENDOTHELIAL DYSFUNCTION
AHLUWALIA A
Shock, Ovid Technologies (Wolters Kluwer Health) vol. 21 (Supplement), 145-145.

DOI 10.1097/00024382-200403001-00579

01-03-2004

Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment
Ahluwalia A, Foster P, Scotland RS, McLean PG, Mathur A, Perretti M, Moncada S, Hobbs AJ
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 101 (5), 1386-1391.

DOI 10.1073/pnas.0304264101

23-01-2004

Bradykinin protects against ischemia/reperfusion injury by opening mitochondrial KATP channels in the endothelial cell: a role for nitric oxide
Foster P, Mathur A, Ahluwalia A

01-01-2004

Protease-activated receptor (PAR)-2 causes endothelium-dependant, NO-independant coronary vasodilatation: involvement of C-fibres and EDHF.
AHLUWALIA A, Sarkar D, Aston D, McLean P
Circ. Res vol. 90, 465-472.
01-01-2004

Endothelial C-type natriuretic peptide regulates coronary blood flow and prevents ischemia-reperfusion injury
Ahluwalia A, Foster P, Prescott C, Hobbs AJ

01-01-2004

Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury - Novel cardioprotective role for endothelium-derived C-type natriuretic peptide
Hobbs A, Foster P, Prescott C, Scotland R, Ahluwalia A
Circulation vol. 110 (10), 1231-1235.

DOI 10.1161/01.CIR.0000141802.29945.34

01-01-2004

Inhibition of leukocyte-endothelial cell interactions by nitric oxide via a cGMP-mediated down-regulation of P-selectin expression.
Ahluwalia A, PERRETTI M, Mathur A, Moncada S, McLean PG, Hobbs AJ, Scotland RS, Foster P
Proceedings of The National Academy of Sciences Usa vol. 101, 1386-1391.
01-01-2004

C-type natriuretic peptide inhibits leukocyte recruitment in vivo via natriuretic peptide receptor-C activation
Scotland R, Foster P, Ahluwalia A, Hobbs AJ

01-01-2004

2003

To b'EET or not to b'EET? That is the question!
Ahluwalia A
Clin Sci vol. 105 (4), 399-401.

DOI 10.1042/CS20030232

01-10-2003

Protection against lipopolysaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice
Chauhan SD, Seggara G, Vo PA, MacAllister RJ, Hobbs AJ, Ahluwalia A
Faseb J vol. 17 (2), 773-+.

DOI 10.1096/fj.02-0668fje

01-02-2003

Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor
Chauhan SD, Nilsson H, Ahluwalia A, Hobbs AJ
Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 100 (3), 1426-1431.

DOI 10.1073/pnas.0336365100

27-01-2003

The role of the endothelium and constitutive NO in LPS-induced vasorelaxation
Vo PA, Tomlinson JAP, Chauhan SD, Ahluwalia A

01-01-2003

Anti-leukocyte properties of a novel non NO-based soluble guanylate cyclase activator, BAY 41-2272
Foster P, Mathur A, McLean P, Perretti M, Moncada S, Ahluwalia A, Hobbs A

01-01-2003

Inorganic nitrite: Protector against ischaemia reperfusion injury in the heart?
Webb A, McLean P, Ahluwalia A, Benjamin N

01-01-2003

Characterisation of eNOS/COX-1 double knockout mice: a novel model for the study of endothelium-derived hyperpolarising factor
Scotland RS, Chauhan SD, Hobbs AJ, Ahluwalia A

01-01-2003

Endothelium-derived hyperpolarising factor (EDHF) is C-type natriuretic peptide (CNP) in mesenteric resistance arteries
Hobbs AJ, Chauhan SD, Nilsson H, Ahluwalia A

01-01-2003

NO contributes to EDHF-like responses in rat small arteries: a role for NO stores
Chauhan S, Rahman A, Nilsson H, Clapp L, MacAllister R, Ahluwalia A
Cardiovasc Res vol. 57 (1), 207-216.

DOI 10.1016/s0008-6363(02)00611-9

01-01-2003

Regulation of kinin B1 receptors in emlothelial cells by laminar shear stress
Vo PA, Syed I, McLean P, Bascands JL, Perretti M, Ahluwalia A

01-01-2003

2002

Protease-Activated Receptor-2 Activation Causes EDHF-Like Coronary Vasodilation
McLean PG, Aston D, Sarkar D, Ahluwalia A
Circulation Research, Ovid Technologies (Wolters Kluwer Health) vol. 90 (4), 465-472.

DOI 10.1161/hh0402.105372

08-03-2002

Mechanisms underlying the vasorelaxant activity of C-type natriuretic peptide (CNP) in rat mesenteric resistance arteries
Chauhan SD, MacAllister RJ, Hobbs AJ, Ahluwalia A
Faseb Journal vol. 16 (4), A572-A572.
01-01-2002

Protease-activated receptor (PAR)-2 activation causes EDHF-like coronary vasodilation: selective preservation in ischemia-reperfusion injury, involvement of lipoxygenase products, VR1 receptors and C-fibers
McLean P, Ahluwalia A
Faseb Journal vol. 16 (4), A569-A569.
01-01-2002

Regulation of GTP Cyclohydrolase I by Estrogen
Hesslinger C, Chen Z, Ahluwalia A, Selwood DL, Vallance P, Pfeilschifter J, Hingorani AD
In Chemistry and Biology of Pteridines and Folates, Springer Us 157-161.

DOI 10.1007/978-1-4615-0945-5_26

01-01-2002

2001

An endothelium-derived hyperpolarizing factor-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of endothelial nitric oxide synthase-derived nitric oxide
Scotland RS, Chauhan S, Vallance PJT, Ahluwalia A
Hypertension vol. 38 (4), 833-839.

DOI 10.1161/hy1001.092651

01-10-2001

Nepadutant Menarini Richerche
Ahluwalia A
Current Opinion in Investigational Drugs vol. 2 (7), 919-922.
14-08-2001

An EDHF-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of eNOS-derived nitric oxide
Ahluwalia A, SCOTLAND RS, Vallance PJ, Chauhan S
Hypertension vol. 38 (4), 833-839.
01-01-2001

2000

Kinin B1 receptors and the cardiovascular system: regulation of expression and function
McLean P
Cardiovascular Research, Oxford University Press (Oup) vol. 48 (2), 194-210.

DOI 10.1016/s0008-6363(00)00184-x

01-11-2000

Association between Kinin B1 Receptor Expression and Leukocyte Trafficking across Mouse Mesenteric Postcapillary Venules
McLean PG, Ahluwalia A, Perretti M
The Journal of Experimental Medicine, Rockefeller University Press vol. 192 (3), 367-380.

DOI 10.1084/jem.192.3.367

31-07-2000

Endogenous factors involved in regulation of tone of arterial vasa vasorum: implications for conduit vessel physiology
Scotland R
Cardiovascular Research, Oxford University Press (Oup) vol. 46 (3), 403-411.

DOI 10.1016/s0008-6363(00)00023-7

01-06-2000

The Microcirculation and Inflammation: Site of Action for Glucocorticoids
PERRETTI M, AHLUWALIA A
Microcirculation, Wiley vol. 7 (3), 147-161.

DOI 10.1111/j.1549-8719.2000.tb00117.x

01-06-2000

Impaired vascular sensitivity to nitric oxide in the coronary microvasculature after endotoxaemia
Bogle RG, McLean PG, Ahluwalia A, Vallance P
British Journal of Pharmacology, Wiley vol. 130 (1), 118-124.

DOI 10.1038/sj.bjp.0703267

01-05-2000

Kinin B₁receptors as novel anti-inflammatory targets
McLean PG, Perretti M, Ahluwalia A
Emerging Therapeutic Targets, Informa Uk Limited vol. 4 (2), 127-141.

DOI 10.1517/14728222.4.2.127

01-04-2000

Evidence that no may contribute to \EDHF-like\ responses in rat mesenteric and hepatic small arteries
Chauhan SD, MacAllister RJ, Clapp LH, Ahluwalia A
British Journal of Pharmacology vol. 129
01-01-2000

Activation of sensory C-fibres partially mediates the vascular myogenic response
Ahluwalia A, Scotland R
Faseb Journal vol. 14 (4), A143-A143.
01-01-2000

1999

Cholinergic Contraction Is Altered in nNOS Knockouts
KAKUYAMA M, AHLUWALIA A, RODRIGO J, VALLANCE P
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society vol. 160 (6), 2072-2078.

DOI 10.1164/ajrccm.160.6.9808105

01-12-1999

Endothelin alters the reactivity of vasa vasorum: mechanisms and implications for conduit vessel physiology and pathophysiology
Scotland R, Vallance P, Ahluwalia A
British Journal of Pharmacology, Wiley vol. 128 (6), 1229-1234.

DOI 10.1038/sj.bjp.0702930

01-11-1999

Inducible expression of the kinin B₁ receptor in the endotoxemic heart: mechanisms of des‐Arg⁹bradykinin‐induced coronary vasodilation
McLean PG, Perretti M, Ahluwalia A
British Journal of Pharmacology, Wiley vol. 128 (2), 275-282.

DOI 10.1038/sj.bjp.0702743

01-09-1999

B1 receptors as a new inflammatory target. Could this B the 1?
Ahluwalia A, Perretti M
Trends in Pharmacological Sciences, Elsevier Bv vol. 20 (3), 100-104.

DOI 10.1016/s0165-6147(99)01321-8

01-03-1999

On the regulation of tone in vasa vasorum
Scotland R
Cardiovascular Research, Oxford University Press (Oup) vol. 41 (1), 237-245.

DOI 10.1016/s0008-6363(98)00223-5

01-01-1999

The involvement of kinin B1 receptors in the hypotensive response to endotoxin in rats
McLean PG, Perretti M, Ahluwalia A
British Journal of Pharmacology vol. 127, U62-U62.
01-01-1999

Investigation of the α₁ adrenoceptor subtype(s) mediating contraction in the human internal mammary artery
Varsani M, MacAllister R, Ahluwalia A, Marshall I
British Journal of Pharmacology vol. 127
01-01-1999

1998

Impaired IL‐1β‐induced neutrophil accumulation in tachykinin NK₁ receptor knockout mice
Ahluwalia A, De Felipe C, O'Brien J, Hunt SP, Perretti M
British Journal of Pharmacology, Wiley vol. 124 (6), 1013-1015.

DOI 10.1038/sj.bjp.0701978

01-07-1998

Ovalbumin‐induced neurogenic inflammation in the bladder of sensitized rats
Ahluwalia A, Giuliani S, Scotland R, Maggi CA
British Journal of Pharmacology, Wiley vol. 124 (1), 190-196.

DOI 10.1038/sj.bjp.0701793

01-05-1998

Topical glucocorticoids and the skin‐mechanisms of action: an update
Ahluwalia A
Mediators of Inflammation, Wiley vol. 7 (3), 183-193.

DOI 10.1080/09629359891126

01-01-1998

Endothelium‐dependent sensory NANC vasodilatation: involvement of ATP, CGRP and a possible NO store
Kakuyama M, Vallance P, Ahluwalia A
British Journal of Pharmacology, Wiley vol. 123 (2), 310-316.

DOI 10.1038/sj.bjp.0701610

01-01-1998

Investigation of endotoxin-inducible B₁ and constitutive B₂ kinin receptors mediating coronary vasodilation in the rat isolated heart.
McLean PG, Perretti M, Ahluwalia A
Naunyn-Schmiedebergs Archives of Pharmacology vol. 358 (1), R335-R335.
01-01-1998

1997

An insight into recent developmens in understanding the mechanisms and management of septic shock
Ahluwalia A, Bhagat K

01-12-1997

Modification of Delivery System Enhances MHC Nonrestricted Immunogenicity of V3 Loop Region of HIV‐1 gp120
Ahluwalia A, Gokulan K, Nath I, Rao DN
Microbiology and Immunology, Wiley vol. 41 (10), 779-784.

DOI 10.1111/j.1348-0421.1997.tb01926.x

01-10-1997

Evidence for Functional Responses to Sensory Nerve Stimulation of Rat Small Mesenteric Veins
Ahluwalia A, Vallance P
The Journal of Pharmacology and Experimental Therapeutics, Elsevier Bv vol. 281 (1), 9-14.

DOI 10.1016/s0022-3565(24)36574-7

01-04-1997

Allergic inflammation in the rat urinary bladder: Involvement of mast cells and C-fibres
Ahluwalia A, Giuliani S, Maggi CA
British Journal of Pharmacology vol. 122
01-01-1997

Regulation of the cardiovascular system by non-adrenergic non-chollnergic nerves
Ahluwalia A, Cellek S
Current Opinion in Nephrology and Hypertension, Ovid Technologies (Wolters Kluwer Health) vol. 6 (1), 74-79.

DOI 10.1097/00041552-199701000-00014

01-01-1997

Comparison of vascular reactivity of porcine aorta and its vasa vasorum
Scotland RS, Vallance PJ, Ahluwalia A
Circulation vol. 96 (8), 908-908.
01-01-1997

Non-adrenergic non-cholinergic relaxation of the rabbit mesenteric small artery: Involvement of NO
Kakuyama M, Vallance PJ, Ahluwalia A
Japanese Journal of Pharmacology, Elsevier Bv vol. 75, 30-30.

DOI 10.1016/s0021-5198(19)41531-x

01-01-1997

1996

Investigation of notalgia paraesthetica using laser Doppler velocimetry and immunohistochemistry before and after treatment with topical capsaicin
Halpern SM, Ahluwalia A, Makunura CN, Jordan S
Journal of The European Academy of Dermatology and Venereology, Wiley vol. 7 (3), 228-234.

DOI 10.1111/j.1468-3083.1996.tb00575.x

01-11-1996

Interaction between sympathetic and sensory nerves in rat small arteries: involvement of nitric oxide
Ahluwalia A, Vallance P
American Journal of Physiology-Heart and Circulatory Physiology, American Physiological Society vol. 271 (3), H969-H976.

DOI 10.1152/ajpheart.1996.271.3.h969

01-09-1996

Acute inflammatory response in the mouse: Exacerbation by immunoneutralization of lipocortin 1
Perretti M, Ahluwalia A, Harris JG, Harris HJ, Wheller SK, Flower RJ
Brit J Pharmacol vol. 117 (6), 1145-1154.

DOI 10.1111/j.1476-5381.1996.tb16709.x

01-03-1996

Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse.
Ahluwalia A, Perretti M
The Journal of Immunology, Oxford University Press (Oup) vol. 156 (1), 269-274.

DOI 10.4049/jimmunol.156.1.269

01-01-1996

Reactivity of the vasa vasorum
Ahluwalia A, Vallance PJ
Circulation vol. 94 (8), 3443-3443.
01-01-1996

1995

Demonstration of a ‘septide‐sensitive’ inflammatory response in rat skin
Ahluwalia A, Giuliani S, Maggi CA
British Journal of Pharmacology, Wiley vol. 116 (4), 2170-2174.

DOI 10.1111/j.1476-5381.1995.tb15050.x

01-10-1995

TOPICAL GLUCOCORTICOIDS INHIBIT NEUROGENIC INFLAMMATION - INVOLVEMENT OF LIPOCORTIN-1
AHLUWALIA A, NEWBOLD P, BRAIN SD, FLOWER RJ
Eur J Pharmacol vol. 283 (1-3), 193-198.

DOI 10.1016/0014-2999(95)00350-t

05-09-1995

TOPICAL GLUCOCORTICOIDS INHIBIT NEUROGENIC INFLAMMATION - INVOLVEMENT OF LIPOCORTIN-1
AHLUWALIA A, NEWBOLD P, FLOWER RJ
Brit J Pharmacol vol. 114, P61-P61.
01-04-1995

DEMONSTRATION OF A SEPTIDE-SENSITIVE INFLAMMATORY RESPONSE IN RAT SKIN
AHLUWALIA A, GIULIANI S, MAGGI CA
British Journal of Pharmacology vol. 114, P41-P41.
01-01-1995

1994

Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse
Ahluwalia A, Perretti M
European Journal of Pharmacology, Elsevier Bv vol. 264 (3), 407-415.

DOI 10.1016/0014-2999(94)00503-6

01-11-1994

INDUCTION OF LIPOCORTIN-1 BY TOPICAL STEROID IN RAT SKIN
AHLUWALIA A, MOHAMED RW, FLOWER RJ
Biochem Pharmacol vol. 48 (8), 1647-1654.

DOI 10.1016/0006-2952(94)90210-0

18-10-1994

CHARACTERIZATION OF CAPSAICIN-INDUCED VASODILATION OF THE PERFUSED RABBIT EAR AND ITS MODULATION BY DEXAMETHASONE
AHLUWALIA A, FLOWER RJ
Brit J Pharmacol vol. 112, U104-U104.
01-05-1994

Characterization of the capsaicin‐sensitive component of cyclophosphamide‐induced inflammation in the rat urinary bladder
Ahluwalia A, Maggi CA, Santicioli P, Lecci A, Giuliani S
British Journal of Pharmacology, Wiley vol. 111 (4), 1017-1022.

DOI 10.1111/j.1476-5381.1994.tb14845.x

01-04-1994

Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors.
Ahluwalia A, Perretti M
The Journal of Pharmacology and Experimental Therapeutics, Elsevier Bv vol. 268 (3), 1526-1531.

DOI 10.1016/s0022-3565(25)38645-3

01-03-1994

1993

LIPOCORTIN-1 FRAGMENTS INHIBIT NEUTROPHIL ACCUMULATION AND NEUTROPHIL-DEPENDENT EDEMA IN THE MOUSE - A QUALITATIVE COMPARISON WITH AN ANTI-CD11B MONOCLONAL-ANTIBODY
PERRETTI M, AHLUWALIA A, HARRIS JG, GOULDING NJ, FLOWER RJ
J Immunol vol. 151 (8), 4306-4314.

DOI 10.4049/jimmunol.151.8.4306

15-10-1993

ENDOGENOUS TACHYKININS PLAY A ROLE IN IL-1-INDUCED NEUTROPHIL ACCUMULATION - INVOLVEMENT OF NK-1 RECEPTORS
PERRETTI M, AHLUWALIA A, FLOWER RJ, MANZINI S
Immunology vol. 80 (1), 73-77.
01-09-1993

DUAL-ACTION OF PROSTAGLANDINS (PGS) IN THE MOUSE SKIN EDEMA TEST
AHLUWALIA A, FLOWER RJ, PERRETTI M
Brit J Pharmacol vol. 109, P5-P5.
01-07-1993

INVESTIGATIONS INTO THE MECHANISM OF VASOCONSTRICTOR ACTION OF THE TOPICAL STEROID BETAMETHASONE-17-VALERATE IN THE RAT
AHLUWALIA A, FLOWER RJ
Brit J Pharmacol vol. 108 (2), 544-548.

DOI 10.1111/j.1476-5381.1993.tb12838.x

01-02-1993

EFFECT OF CHRONIC CAPSAICIN AND GUANETHIDINE TREATMENT ON SKIN BLOOD-FLOW OF THE RAT
AHLUWALIA A, FLOWER RJ

DOI 10.1007/BF01991123

01-01-1993

TOPICAL BETAMETHASONE-17-VALERATE INHIBITS HEAT-INDUCED VASODILATATION IN MAN
AHLUWALIA A, FLOWER RJ
Brit J Dermatol vol. 128 (1), 45-48.

DOI 10.1111/j.1365-2133.1993.tb00146.x

01-01-1993

1992

TOPICAL STEROIDS AND ACE INHIBITORS - A COMMON LINK
AHLUWALIA A, FLOWER RJ
Brit J Pharmacol vol. 106, P5-P5.
01-07-1992

STEROID INHIBITION OF EDEMA FORMATION IN THE RAT SKIN
AHLUWALIA A, PEERS SH, FLOWER RJ
Brit J Pharmacol vol. 106 (3), 628-631.

DOI 10.1111/j.1476-5381.1992.tb14386.x

01-07-1992

Sodium Nitrite Poisoning: A Series of 20 Fatalities in Which Post-Mortem Blood Nitrite and Nitrate Concentrations are Reported
Hikin LJ, Ho J, Ahluwalia A, Smith P

DOI 10.2139/ssrn.4213190

The NITRATE-CIN Study: A randomised, double-blind placebo-controlled trial testing the effect of inorganic nitrate on contrast-induced nephropathy in patients undergoing coronary angiography for acute coronary syndromes
Ahluwalia A
European Heart Journal, Oxford University Press

DOI 10.1093/eurheartj/ehae100

QMRO

Grants

Clinical Effectiveness and Mechanisms of Action of Gonadotropins for Pubertal Induction in Adolescent & Young Adult Males with Gonadotropin Deficiency
Sasha Howard and Amrita Ahluwalia
£1,939,075 NIHR National Institute for Health Research
01-04-2025 - 31-03-2029

Continuum-Lint QM Abbott funding
Anthony Mathur and Amrita Ahluwalia
£174,960 Abbott Medical UK Ltd
01-12-2024 - 30-09-2025

Feasibility study to determine the potential for a food fortification platform to provide population scale mitigation of heart disease risk
Amrita Ahluwalia and Anthony Mathur
£120,848 Innovate UK
01-10-2024 - 31-12-2025

QMUL 4th Intake 2024, 4 Year PhD Studentship (5th) Scheme
Amrita Ahluwalia
£479,408 BHF British Heart Foundation
01-10-2024 - 30-09-2028

Enhancing Cardiovascular cGMP to Target Hypertensive Heart Failure in Females
Amrita Ahluwalia
£139,727 NHMRC National Health and Medical Research Council (Australia)
02-04-2024 - 01-04-2027

QMUL 3rd intake, 2023 4-Year PhD Studentship (5th) Scheme
Amrita Ahluwalia
£479,924 BHF British Heart Foundation
01-10-2023 - 30-09-2027

A randomised trial assessing the duration of anti-coagulation treatment for LV thrombus QMUL Part
Daniel Jones and Amrita Ahluwalia
£277,790 Barts and the London Charity
01-03-2023 - 28-02-2026

QMUL 2nd intake 2022 - 4 Year PhD Studentship (5th) Scheme
Amrita Ahluwalia
£447,561 BHF British Heart Foundation
01-10-2022 - 30-09-2026

Randomised Control Trial: Cryoballoon/Radio frequency ablation of a trial fibrillation versus medical treatment for heart failureTreatment
Amrita Ahluwalia
£975,493 BHF British Heart Foundation
01-09-2022 - 28-02-2028

Clinical Investigation of the Tricento Tricuspid Valve for TR in Patients with Carcinoid HD
Andreas Baumbach, Anthony Mathur, Ruth Bowles and Amrita Ahluwalia
£369,055 Barts and the London Charity
01-08-2022 - 31-12-2026

Assessment of nitrite/nitrate in biological samples
Amrita Ahluwalia
£150,000 WHRL William Harvey Research Limited
01-07-2022 - 31-12-2025

Evaluation of Sirolimus Drug Eluting Balloon(SELUTION SLRTM)for Treatment of De-Novo Coronary Artery Disease in an All-comers Patient Population(SELUTIONCADUK-I)
Amrita Ahluwalia
£270,250 Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust
01-02-2022 - 31-05-2026

BHF 4 Year PhD Studentships (2021 - 2024 intakes)
Amrita Ahluwalia
£444,465 BHF British Heart Foundation
01-10-2021 - 30-09-2025

A Multi Site, Placebo Controlled, Double Blind Randomised Clinical Trial Evaluating The Effectiveness Of Sodium Zirconium Cyclosilicate Versus Placebo To Enable Safe Optimisation Of RASi Therapy In Patients With Diabetic Kidney Disease QM
Amrita Ahluwalia
£217,020 BH NHS Barts Health NHS
01-04-2022 - 30-09-2024

DiNOmo-HF Crowdfunding: Investigation of Dietary Nitrate Optimisation by hyperuricaeamia stratification of Heart Failure
Amrita Ahluwalia and Christopher Primus
£5,000 Barts and the London Charity
01-01-2021 - 31-12-2021

Therapeutic utility of targeting C-type natriuretic peptide to maintain endothelial integrity
Adrian Hobbs and Amrita Ahluwalia
£334,632 MRC Medical Research Council
05-10-2020 - 31-07-2025

BHF 4-Year PhD Studentship Award
Amrita Ahluwalia
£594,796 BHF British Heart Foundation
01-10-2020 - 30-09-2024

Therapeutics or Clinical Pharmacology- Krishnaraj Sinhji Rathod
Amrita Ahluwalia
£507,914 NIHR National Institute for Health Research
02-10-2019 - 01-10-2023

BHF 4-Year PhD Studentship Award (3rd Intake 2019 OF 4th Scheme)
Amrita Ahluwalia
£653,416 BHF British Heart Foundation
01-10-2019 - 30-09-2023

A Multi site, placebo controlled, double blind randomised clinical trial evaluating the effectiveness of sodium zirconium cyclosilicate versus placebo to enable safe optimisation of RASi therapy in patients with diabetic kidney disease.
Kieran McCafferty and Amrita Ahluwalia
£559,581 AZ AstraZeneca UK Limited
01-09-2019 - 31-12-2021

Inorganic nitrate treatment reduces inflammation in humans: assessment of mechanisms
Amrita Ahluwalia, Rob Krams, Federica Marelli-Berg and Jacqueline Cooper
£206,297 British Heart Foundation
19-08-2019 - 18-02-2022

Analysis of the microbiome in patients with stable angina
Amrita Ahluwalia and Krishnaraj Rathod
£49,966 Barts and the London Charity
01-06-2019 - 31-05-2020

A phase 2, Randomized, 3 Arm Parallel Group, Placebo and Active-Controlled Study of the Effect of PL-8177 Administered via Sub-cutaneous Injection in Healthy Male Volunteers on Inflammatory Onset and Resolution
Amrita Ahluwalia and Jesmond Dalli
£545,919 Palatin Technologies
01-05-2019 - 30-04-2022

TRP13/17 Effect of inorganic nitrate on contrast-induced nephropathy in patients undergoing coronary angiograph/ percutaneous coronary intervention for Acute Coronary Syndrome (ACS): A randomised single-centre, double-blind placebo-controlled trial
Amrita Ahluwalia, Anthony Mathur and Daniel Jones
£144,825 HRUK Heart Research UK
25-10-2018 - 31-12-2022

Assessment of the effects of nutritional extracts upon endothelial cell function
Amrita Ahluwalia
£95,939 WHRL William Harvey Research Limited
18-10-2018 - 31-12-2021

BHF 4-Year PhD Studentship Award- 2nd intake
Amrita Ahluwalia
£652,264 BHF British Heart Foundation
01-10-2018 - 30-09-2022

BHF 4-Year PhD Studentship Award
Amrita Ahluwalia
£692,452 BHF British Heart Foundation
01-10-2017 - 28-02-2022

Investigation of Dietary Nitrate Optimisation by hyperuricaemia
Amrita Ahluwalia and Christopher Primus
£186,644 Willoughby Trustees
01-10-2017 - 28-02-2021

Generation of a floxed Xdh gene knockout mourse
Amrita Ahluwalia
£39,000 Barts and the London Charity
01-08-2017 - 31-07-2018

Delineating physiological and pathological regulatory roles for C-type natriuretic peptide in cardiac structure and function
Adrian Hobbs and Amrita Ahluwalia
£817,911 British Heart Foundation
01-10-2016 - 28-02-2022

Phenotyping of the xanthine dehydrogenase knockout mouse: effects on nitrite reduction
Amrita Ahluwalia
£41,875 WHRL William Harvey Research Limited
01-09-2015 - 31-08-2018

Creating global leadership in cardiovascular care, research and education
Amrita Ahluwalia
£10,276,879 Barts and the London Charity
01-07-2015 - 31-03-2024