Dr Pradeepa Madapura
Senior Lecturer
Blizard Institute
Queen Mary University of London
Queen Mary University of London
Research
Neurodevelopmental disorders, brain organoids, In vitro brain development, neuroepigenetics, functional genomics
Interests
We use human stem cell-derived cerebral organoid models to investigate the mechanism through which mutations in epigenetic regulators contribute to neurodevelopmental and cardiovascular disorders.Publications
2024

Jayakumar S, Patel M, Boulet F, Aziz H, Brooke GN, Tummala H, Pradeepa MM
Nature Communications, Springer Nature vol. 15 (1)
07-06-2024

Jacob DR, Guiblet WM, Mamayusupova H, Shtumpf M, Ciuta I, Ruje L, Gretton S, Bikova M et al.
Clinical Epigenetics, Springer Nature vol. 16 (1)
01-04-2024

Jayakumar S, Patel M, Boulet F, Aziz H, Brooke GN, Tummala H, Pradeepa MM
Nature Communications, Springer Nature vol. 15 (1)
08-01-2024
2023

Pal D, Patel M, Boulet F, Sundarraj J, Grant OA, Branco MR, Basu S, Santos SDM et al.
Nature Structural & Molecular Biology, Springer Nature vol. 30 (7), 935-947.
12-06-2023

De Vas MG, Boulet F, Joshi SS, Garstang MG, Khan TN, Atla G, Parry D, Moore D et al.
Life Science Alliance, Life Science Alliance vol. 6 (5)
28-02-2023
2022

Genome Biology, Springer Nature vol. 23 (1)
14-02-2022
2021

Sundarraj J, Taylor GCA, von Kriegsheim A, Pradeepa MM
Wellcome Open Research, F1000research vol. 2
14-09-2021

Sundarraj J, Taylor GCA, von Kriegsheim A, Pradeepa MM
Wellcome Open Research, F1000research vol. 2
16-08-2021

Olley G, Pradeepa MM, Grimes GR, Piquet S, Polo SE, FitzPatrick DR, Bickmore WA, Boumendil C
Nature Communications, Springer Nature vol. 12 (1)
25-05-2021
2019

Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ et al.
Nature Genetics, Springer Nature vol. 51 (7), 1192-1192.
03-06-2019
2018

Garstang MG, Pradeepa MM
Mol Cell vol. 71 (1), 3-5.
05-07-2018

Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ et al.
Nature Genetics, Springer Nature vol. 50 (5), 767-767.
12-02-2018

Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ et al.
Nature Genetics, Springer Nature vol. 50 (3), 329-332.
29-01-2018
2017

Marin R, Cortez D, Lamanna F, Pradeepa MM, Leushkin E, Julien P, Liechti A, Halbert J et al.
Genome Research, Cold Spring Harbor Laboratory vol. 27 (12), 1974-1987.
13-11-2017

Pradeepa MM, Taylor GCA, von Kriegsheim A
Wellcome Open Research, F1000research vol. 2
12-09-2017

Pradeepa MM, McKenna F, Taylor GCA, Bengani H, Grimes GR, Wood AJ, Bhatia S, Bickmore WA
Plos Genetics, Public Library of Science (Plos) vol. 13 (4)
06-04-2017

Pradeepa MM
Transcription vol. 8 (1), 40-47.
01-01-2017
2016

Marulasiddappa P, Pradeepa MM, Kumar Y, Grimes G, Illingworth R, Bickmore W
Protocol Exchange, Springer Nature
05-05-2016

Pradeepa MM, Grimes GR, Kumar Y, Olley G, Taylor GCA, Schneider R, Bickmore WA
Nature Genetics vol. 48 (6), 681-686.
18-04-2016

Robertson KA, Hsieh WY, Forster T, Blanc M, Lu H, Crick PJ, Yutuc E, Watterson S et al.
Plos Biology, Public Library of Science (Plos) vol. 14 (3)
03-03-2016
2015

Illingworth RS, Moffat M, Mann AR, Read D, Hunter CJ, Pradeepa MM, Adams IR, Bickmore WA
Genes & Development, Cold Spring Harbor Laboratory vol. 29 (18), 1897-1902.
15-09-2015

Gupta N, Madapura MP, Bhat UA, Rao MRS
Journal of Biological Chemistry, Elsevier vol. 290 (19), 12101-12122.
28-03-2015
2014

Pradeepa MM, Grimes GR, Taylor GCA, Sutherland HG, Bickmore WA
Nucleic Acids Research, Oxford University Press (Oup) vol. 42 (14), 9021-9032.
23-07-2014
2013

Taylor GCA, Eskeland R, Hekimoglu-Balkan B, Pradeepa MM, Bickmore WA
Genome Research, Cold Spring Harbor Laboratory vol. 23 (12), 2053-2065.
29-08-2013
2012

Pradeepa MM, Sutherland HG, Ule J, Grimes GR, Bickmore WA
Plos Genetics, Public Library of Science (Plos) vol. 8 (5)
01-01-2012
2009

Pradeepa MM, Nikhil G, Kishore AH, Bharath GN, Kundu TK, Rao MRS
Journal of Biological Chemistry, Elsevier vol. 284 (43), 29956-29967.
26-08-2009

Kolthur-Seetharam U, Pradeepa MM, Gupta N, Narayanaswamy R, Rao MRS
Journal of Histochemistry & Cytochemistry, Sage Publications vol. 57 (10), 951-962.
08-06-2009
2008

Pradeepa MM, Manjunatha S, Sathish V, Agrawal S, Rao MRS
Molecular and Cellular Biology, Taylor & Francis vol. 28 (13), 4331-4341.
01-07-2008
2007

Pradeepa MM, Rao MRS
Society of Reproduction and Fertility vol. 63, 1-10.
01-01-2007

Dhar S, Pradeepa MM, Rao MRS
Proceedings of The National Academy of Sciences India Section B-Biological Sciences vol. 77, 61-71.
01-01-2007
Grants

Pradeepa Madapura
£74,499 Barts and the London Charity
11-06-2025 - 10-06-2026

Pradeepa Madapura
£759,321 MRC Medical Research Council
01-11-2023 - 31-10-2026

Pradeepa Madapura and Nicolae Radu Zabet
£205,822 Barts and the London Charity
01-04-2023 - 31-03-2027

Pradeepa Madapura
£179,947 EU Commission - Horizon 2020
05-01-2021 - 18-01-2023

Pradeepa Madapura
£821,014 MRC Medical Research Council
01-02-2020 - 31-10-2023

Pradeepa Madapura
£40,000 Barts and the London Charity
01-09-2019 - 31-08-2021