Dr Muy-Teck Teh

Muy-Teck Teh

Senior Lecturer

Centre for Oral Immunobiology & Regenerative Medicine, Institute
Queen Mary University of London
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Research

cancer spheroids, 3D in vitro culture model, chemoresistance, high-throughput 3D drug screening, transcriptome pattern recognition, mRNA biomarkers

Cancer Models

Interests

We are developing a high-throughput 3D cancer spheroid drug screening method to identify drugs that could counteract chemoresistance and identify transcriptome biomarker for predicting drug-gene interaction.

Publications

Publications of specific relevance to Predictive in vitro Models

2024

Usman S, Bushaala A, Teh MT and Waseem A (2024). Site-Directed Mutagenesis to Mutate Multiple Residues in a Single Reaction. Springer Nature  10.1007/7651_2023_511

2023

Wan H, Teh M-T, Mastroianni G and Ahmad US (2023). Comparative Transcriptome Analysis Identifies Desmoglein-3 as a Potential Oncogene in Oral Cancer Cells. Mdpi  Cells  vol. 12, (23) 10.3390/cells12232710
Teh M-T (2023). Identification of multidrug chemoresistant genes in head and neck squamous cell carcinoma cells. Biomed Central  Molecular Cancer  10.1186/s12943-023-01846-3
Perussolo J, Teh M-T, Gkranias N, Tiberi S, Petrie A, Cutino-Moguel M-T and Donos N (2023). Efficacy of three antimicrobial mouthwashes in reducing SARS-CoV-2 viral load in the saliva of hospitalized patients: a randomized controlled pilot study. Springer Nature  Scientific Reports  vol. 13, (1) 10.1038/s41598-023-39308-x

2022

Waseem A (2022). Transcriptome Analysis Reveals Vimentin-Induced Disruption of Cell–Cell Associations Augments Breast Cancer Cell Migration. Mdpi  Cells  10.3390/cells11244035
Usman S, Aldehlawi H, Nguyen TKN, Teh M-T and Waseem A (2022). Impact of N-Terminal Tags on De Novo Vimentin Intermediate Filament Assembly. Mdpi  International Journal of Molecular Sciences  vol. 23, (11) 6349-6349. 10.3390/ijms23116349
Teh M-T (2022). Molecular Signatures of Tumour and Its Microenvironment for Precise Quantitative Diagnosis of Oral Squamous Cell Carcinoma: An International Multi-Cohort Diagnostic Validation Study. Mdpi Ag  Cancers  10.3390/cancers14061389
Mech AM, Merteroglu M, Sealy IM, Teh M-T, White RJ, Havelange W, Brennan CH and Busch-Nentwich EM (2022). Behavioral and Gene Regulatory Responses to Developmental Drug Exposures in Zebrafish. Frontiers  Frontiers in Psychiatry  vol. 12, 10.3389/fpsyt.2021.795175

2021

Sapkota D, Sharma S, Søland TM, Braz‐Silva PH and Teh M (2021). Expression profile of SARS‐CoV‐2 cellular entry proteins in normal oral mucosa and oral squamous cell carcinoma. Wiley  Clinical and Experimental Dental Research  10.1002/cre2.510
Usman S (2021). Vimentin Is at the Heart of Epithelial Mesenchymal Transition (EMT) Mediated Metastasis., Editors: Philip Gregory . Mdpi  Cancers  vol. 13, (19) 4985-4985. 10.3390/cancers13194985
Ponzoni L, Melzi G, Marabini L, Martini A, Petrillo G, Teh M-T, Torres-Perez JV, Morara S, Gotti C, Braida D, Brennan CH and Sala M (2021). Conservation of mechanisms regulating emotional-like responses on spontaneous nicotine withdrawal in zebrafish and mammals. Elsevier  Progress in Neuro-Psychopharmacology and Biological Psychiatry  vol. 111, 10.1016/j.pnpbp.2021.110334
Usman S, Jamal A, Teh M-T and Waseem A (2021). Major Molecular Signaling Pathways in Oral Cancer Associated With Therapeutic Resistance. Frontiers in Oral Health  vol. 1, 603160-603160. 10.3389/froh.2020.603160

2020

Ponzoni L, Teh MT, Torres-Perez JV, Brennan CH, Braida D and Sala M (2020). Increased Response to 3,4-Methylenedioxymethamphetamine (MDMA) Reward and Altered Gene Expression in Zebrafish During Short- and Long-Term Nicotine Withdrawal. Springer (Part of Springer Nature)  Molecular Neurobiology  10.1007/s12035-020-02225-5
Teh M-T (2020). RASSF1A inhibits PDGFB-driven malignant phenotypes of nasopharyngeal carcinoma cells in a YAP1-dependent manner. Nature Publishing Group  Cell Death and Disease  10.1038/s41419-020-03054-z
Garcia Gonzalez J, Brock A, Parker M, Riley R, Joliffe D, SUDWARTS A, Teh M-T, Busch-Nentwich E, Stemple D, Martineau A, Kaprio J, Kuan V, Walton R and Brennan C (2020). Identification of Slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour. Elife Sciences Publications Ltd  Elife  10.7554/eLife.51295
Aldehlawi H, Usman S, Lalli A, Ahmad F, WILLIAMS G, Teh M-T and Waseem A (2020). Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes. Nature Publishing Group  Scientific Reports  vol. 10, (4829) 10.1038/s41598-020-61640-9
Teh M-T (2020). A Novel Diagnostic Tool for Cancer Detection. Science Diffusion Ltd  Scientia  10.33548/scientia572

2019

Uttagomol J, Ahmad US, Rehman A, Huang Y, Laly AC, Kang A, Soetaert J, Chance R, Teh M-T, Connelly JT and Wan H (2019). Evidence for the Desmosomal Cadherin Desmoglein-3 in Regulating YAP and Phospho-YAP in Keratinocyte Responses to Mechanical Forces. Mdpi  International Journal of Molecular Sciences  vol. 20, (24) 10.3390/ijms20246221
Teh M-T (2019). The transcription factor FOXM1 regulates the balance between proliferation and aberrant differentiation in head and neck squamous cell carcinoma. Wiley  Journal of Pathology  10.1002/path.5342
Yeung J-YS, Hutchison I, Waseem A and Teh M-T (2019). qMIDS: A Digital Diagnostic Test for Oral Cancer. British Journal of Oral and Maxillofacial Surgery  vol. 57, (10) e86-e87. 10.1016/j.bjoms.2019.10.252
Rehman A, Cai Y, Hünefeld C, Jedličková H, Huang Y, Teck Teh M, Sharif Ahmad U, Uttagomol J, Wang Y, Kang A, Warnes G, Harwood C, Bergamaschi D, Kenneth Parkinson E, Röcken M and Wan H (2019). The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53. Springer Nature  Cell Death & Disease  vol. 10, (10) 10.1038/s41419-019-1988-0
Teh M-T (2019). Clinical correlation of opposing molecular signatures in head and neck squamous cell carcinoma. Biomed Central  Bmc Cancer  10.1186/s12885-019-6059-5
ALDEHLAWI H, Niemiec NA, AVISETTI DR, LALLI A, Teh M-T and WASEEM A (2019). The monoclonal antibody EPR1614Y against the stem cell biomarker keratin K15 lacks specificity and reacts with other keratins. Nature Publishing Group  Scientific Reports  vol. 9, 10.1038/s41598-018-38163-5

2018

TEH M (2018). Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation. Biomed Central  Molecular Cancer  10.1186/s12943-018-0846-5

2017

Pantazi E, Gemenetzidis E, Teh M-T, Reddy SV, Warnes G, Evagora C, Trigiante G and Philpott MP (2017). GLI2 Is a Regulator of β-Catenin and Is Associated with Loss of E-Cadherin, Cell Invasiveness, and Long-Term Epidermal Regeneration. Elsevier  Journal of Investigative Dermatology  vol. 137, (8) 1719-1730. 10.1016/j.jid.2016.11.046

2016

Parajuli H, Teh MT, Abrahamsen S, Christoffersen I, Neppelberg E, Lybak S, Osman T, Johannessen AC, Gullberg D, Skarstein K and Costea DE (2016). Integrin α11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression. J Oral Pathol Med  10.1111/jop.12493
TEH M and Wan HONG (2016). Independent Evaluation of a FOXM1-based Quantitative Malignancy Diagnostic System (qMIDS) on Head and Neck Squamous Cell Carcinomas. Impact Journals  Oncotarget  vol. 7, (34) 54555-54563. 10.18632/oncotarget.10512
TEH M (2016). Oral Cancer Biomarkers: Is it a Meaningless Game?, Editors: TEH M. Openventio  Dentistry Open Journal  vol. 3, (1) e1-e3. 10.17140/DOJ-3-e005

2015

Parker MO, Brock AJ, Sudwarts A, Teh M-T, Combe FJ and Brennan CH (2015). Developmental role of acetylcholinesterase in impulse control in zebrafish. Frontiers  Frontiers in Behavioral Neuroscience  vol. 9, 10.3389/fnbeh.2015.00271
Sapkota D, Bruland O, Parajuli H, Osman TA, Teh M-T, Johannessen AC and Costea DE (2015). S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma. Springer Nature  Bmc Cancer  vol. 15, (1) 10.1186/s12885-015-1622-1
TEH M (2015). Is Salivary Exosome the Answer to Early Detection of Oral Cancer? Openventio Publishers  Dentistry Open Journal  vol. 2, (2) e3-e4. 10.17140/DOJ-2-e002
Teh M-T (2015). Can Challenges of Oral Cancer Diagnosis be Resolved? Omics International  Dental Health Current Research  vol. 01, (01) 10.4172/2470-0886.1000e103

2014

Parker MO, Annan LV, Kanellopoulos AH, Brock AJ, Combe FJ, Baiamonte M, Teh MT and Brennan CH (2014). The utility of zebrafish to study the mechanisms by which ethanol affects social behavior and anxiety during early brain development. Progress in Neuro-Psychopharmacology and Biological Psychiatry  vol. 55, 94-100. 10.1016/j.pnpbp.2014.03.011
Parker MO, Evans AM-D, Brock AJ, Combe FJ, Teh M-T and Brennan CH (2014). PNE and habit. Wiley  Addiction Biology  vol. 21, (1) 49-60. 10.1111/adb.12176
Schmidt BL, Kuczynski J, Bhattacharya A, Huey B, Corby PM, Queiroz ELS, Nightingale K, Kerr AR, DeLacure MD, Veeramachaneni R, Olshen AB and Albertson DG (2014). Changes in Abundance of Oral Microbiota Associated with Oral Cancer. Public Library of Science (Plos)  Plos One  vol. 9, (6) 10.1371/journal.pone.0098741
Parker MO, Annan LV, Kanellopoulos AH, Brock AJ, Combe FJ, Baiamonte M, Teh M-T and Brennan CH (2014). The utility of zebrafish to study the mechanisms by which ethanol affects social behavior and anxiety during early brain development. Elsevier  Progress in Neuro-Psychopharmacology and Biological Psychiatry  vol. 55, 94-100. 10.1016/j.pnpbp.2014.03.011
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh M-T, Lu Y-J and Philpott MP (2014). GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis. Cell Death Dis  vol. 5, (1) 10.1038/cddis.2013.535

2013

Hwang S, Mahadevan S, Qadir F, Hutchison IL, Costea DE, Neppelberg E, Liavaag PG, Waseem A and Teh M-T (2013). Identification of FOXM1-induced epigenetic markers for head and neck squamous cell carcinomas. Cancer  vol. 119, (24) 4249-4258. 10.1002/cncr.28354
Bose A, Teh M-T, Mackenzie IC and Waseem A (2013). Keratin K15 as a Biomarker of Epidermal Stem Cells. Mdpi  International Journal of Molecular Sciences  vol. 14, (10) 19385-19398. 10.3390/ijms141019385
Teh M-T, Hutchison IL, Costea DE, Neppelberg E, Liavaag PG, Purdie K, Harwood C, Wan H, Odell EW, Hackshaw A and Waseem A (2013). Exploiting FOXM1-orchestrated molecular network for early squamous cell carcinoma diagnosis and prognosis. Int J Cancer  vol. 132, (9) 2095-2106. 10.1002/ijc.27886

2012

Teh M-T (2012). Cells brainwashed by FOXM1: do they have potential as biomarkers of cancer? Biomark Med  vol. 6, (4) 499-501. 10.2217/bmm.12.33
Pitiyage GN, Lim KP, Gemenitzidis E, Teh M, Waseem A, Prime SS, Tilakaratne WM, Fortune F and Parkinson EK (2012). Increased secretion of tissue inhibitors of metalloproteinases 1 and 2 (TIMPs ‐1 and ‐2) in fibroblasts are early indictors of oral sub‐mucous fibrosis and ageing. Wiley  Journal of Oral Pathology and Medicine  vol. 41, (6) 454-462. 10.1111/j.1600-0714.2012.01129.x
Teh M-T, Gemenetzidis E, Patel D, Tariq R, Nadir A, Bahta AW, Waseem A and Hutchison IL (2012). FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma. Plos One  vol. 7, (3) 10.1371/journal.pone.0034329
Bose A, Teh M-T, Hutchison IL, Wan H, Leigh IM and Waseem A (2012). Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling. Plos One  vol. 7, (6) 10.1371/journal.pone.0038599
Teh M-T (2012). FOXM1 coming of age: time for translation into clinical benefits? Front Oncol  vol. 2, 10.3389/fonc.2012.00146

2011

TEH M (2011). Chapter 14: Initiation of Human Tumourigenesis: Upregulation of FOXM1 Transcription Factor. Stem Cells and Cancer Stem Cells,Volume 3 , Editors: Hayat MA. Springer Verlag 
Teh M-T (2011). Initiation of Human Tumourigenesis: Upregulation of FOXM1 Transcription Factor. Stem Cells and Cancer Stem Cells,Volume 3  Springer Nature  10.1007/978-94-007-2415-0_14
(2011). Correction: Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1. American Association For Cancer Research (Aacr)  Cancer Research  vol. 71, (1) 290-290. 10.1158/0008-5472.can-10-4082
Teh M-T, Parkinson EK, Thurlow JK, Liu F, Fortune F and Wan H (2011). A molecular study of desmosomes identifies a desmoglein isoform switch in head and neck squamous cell carcinoma. J Oral Pathol Med  vol. 40, (1) 67-76. 10.1111/j.1600-0714.2010.00951.x

2010

Gemenetzidis E, Costea DE, Parkinson EK, Waseem A, Wan H and Teh MT (2010). Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1. American Association For Cancer Research  Cancer Research  vol. 22, (70) 9515-9526. 10.1158/0008-5472.CAN-10-2173
Waseem A, Ali M, Odell EW, Fortune F and Teh M-T (2010). Downstream targets of FOXM1: CEP55 and HELLS are cancer progression markers of head and neck squamous cell carcinoma. Oral Oncol  vol. 46, (7) 536-542. 10.1016/j.oraloncology.2010.03.022
Wang HX, Teh MT, Ji YM, Patel V, Firouzabadian S, Patel AA, Gutkind JS and Yeudall WA (2010). EPS8 upregulates FOXM1 expression, enhancing cell growth and motility. Carcinogenesis  vol. 31, (6) 1132-1141. 10.1093/carcin/bgq058
Teh M-T, Gemenetzidis E, Chaplin T, Young BD and Philpott MP (2010). Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes. Mol Cancer  vol. 9, 10.1186/1476-4598-9-45
Gemenetzidis E, Elena-Costea D, Parkinson EK, Waseem A, Wan H and Teh MT (2010). Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1. American Association For Cancer Research.  Cancer Research  vol. 70, (22) 9515-9526. 10.1158/0008-5472.CAN-10-2173
Tsang SM, Liu L, Teh M-T, Wheeler A, Grose R, Hart IR, Garrod DR, Fortune F and Wan H (2010). Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src. Plosone  Plos One  vol. 5, (12) 10.1371/journal.pone.0014211

2009

Gemenetzidis E, Bose A, Riaz AM, Chaplin T, Young BD, Ali M, Sugden D, Thurlow JK, Cheong S-C, Teo S-H, Wan H, Waseem A, Parkinson EK, Fortune F and Teh M-T (2009). FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation. Plos One  vol. 4, (3) 10.1371/journal.pone.0004849

2008

Teh MT, Tilakaratne WM, Chaplin T, Young BD, Ariyawardana A, Pitiyage G, Lalli A, Stewart JE, Hagi-Pavli E, Cruchley A, Waseem A and Fortune F (2008). Fingerprinting genomic instability in oral submucous fibrosis. J Oral Pathol Med  vol. 37, (7) 430-436. 10.1111/j.1600-0714.2008.00643.x
Tilakaratne WM, Iqbal Z, Teh MT, Ariyawardana A, Pitiyage G, Cruchley A, Stewart JE, Hagi-Pavli E, Lalli A, Waseem A, Parkinson EK and Fortune F (2008). Upregulation of HIF-1 alpha in malignant transformation of oral submucous fibrosis. J Oral Pathol Med  vol. 37, (6) 372-377. 10.1111/j.1600-0714.2007.00625.x
Lalli A, Tilakaratne WM, Ariyawardana A, Fitchett C, Leigh IM, Hagi-Pavli E, Cruchley AT, Parkinson EK, Teh MT, Fortune F and Waseem A (2008). An altered keratinocyte phenotype in oral submucous fibrosis: correlation of keratin K17 expression with disease severity. J Oral Pathol Med  vol. 37, (4) 211-220. 10.1111/j.1600-0714.2007.00609.x

2007

Purdie KJ, Lambert SR, Teh M-T, Chaplin T, Molloy G, Raghavan M, Kelsell DP, Leigh IM, Harwood CA, Proby CM and Young BD (2007). Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis. Genes Chromosomes Cancer  vol. 46, (7) 661-669. 10.1002/gcc.20447
Faust R, Garratt PJ, Perez MAT, Piccio VJD, Madsen C, Stenstrom A, Frolund B, Davidson K, Teh MT and Sugden D (2007). 7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: Effect of substituents on potency and binding affinity. Bioorgan Med Chem  vol. 15, (13) 4543-4551. 10.1016/j.bmc.2007.04.013
Tilakaratne W, Iqbal Z, Teh MT, Ariyawardana A, Pitiyage G, Cruchley A, Hagi-Pavli E, Lalli A, Waseem A, Parkinson K and Fortune F (2007). P245 Up regulation of HIF-1a in the progression and malignant transformation of oral submucous fibrosis. Elsevier  Oral Oncology Supplement  vol. 2, (1) 204-205. 10.1016/s1744-7895(07)70522-9
Teh MT, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM, Kelsell DP and Philpott MP (2007). Erratum: Role for WNT16B in human epidermal keratinocyte proliferation and differentiation (Journal of Cell Science vol. 120 (330-339)). Journal of Cell Science  vol. 120, (5) 10.1242/jcs.03421
Teh MT, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM, Kelsell DP and Philpott MP (2007). Role for WNT16B in human epidermal keratinocyte proliferation and differentiation (vol 120, pg 330, 2007). J Cell Sci  vol. 120, (5) 917-917. 10.1242/jcs.03329
Teh M-T, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM, Kelsell DP and Philpott MP (2007). Role for WNT16B in human epidermal keratinocyte proliferation and differentiation. J Cell Sci  vol. 120, (Pt 2) 330-339. 10.1242/jcs.03329

2006

Blaydon DC, Ishii Y, O'Toole EA, Unsworth HC, Teh M-T, Rüschendorf F, Sinclair C, Hopsu-Havu VK, Tidman N, Moss C, Watson R, de Berker D, Wajid M, Christiano AM and Kelsell DP (2006). The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia. Nat Genet  vol. 38, (11) 1245-1247. 10.1038/ng1883
Tsotinis A, Vlachou M, Papahatjis DP, Calogeropoulou T, Nikas SP, Garratt PJ, Piccio V, Vonhoff S, Davidson K, Teh MT and Sugden D (2006). Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines. J Med Chem  vol. 49, (12) 3509-3519. 10.1021/jm0512544

2005

Teh M-T, Blaydon D, Chaplin T, Foot NJ, Skoulakis S, Raghavan M, Harwood CA, Proby CM, Philpott MP, Young BD and Kelsell DP (2005). Genomewide single nucleotide polymorphism microarray mapping in basal cell carcinomas unveils uniparental disomy as a key somatic event. Cancer Res  vol. 65, (19) 8597-8603. 10.1158/0008-5472.CAN-05-0842
Kelsell DP, Norgett EE, Unsworth H, Teh M-T, Cullup T, Mein CA, Dopping-Hepenstal PJ, Dale BA, Tadini G, Fleckman P, Stephens KG, Sybert VP, Mallory SB, North BV, Witt DR, Sprecher E, Taylor AEM, Ilchyshyn A, Kennedy CT, Goodyear H, Moss C, Paige D, Harper JI, Young BD, Leigh IM, Eady RAJ and O'Toole EA (2005). Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis. Am J Hum Genet  vol. 76, (5) 794-803. 10.1086/429844

2004

Sugden D, Davidson K, Hough KA and Teh M-T (2004). Melatonin, melatonin receptors and melanophores: a moving story. Pigment Cell Res  vol. 17, (5) 454-460. 10.1111/j.1600-0749.2004.00185.x
Davies DJ, Faust R, Garratt PJ, Marivingt-Mounir C, Davidson K, Teh MT and Sugden D (2004). Binding affinity and biological activity of oxygen and sulfur isosteres at melatonin receptors as a function of their hydrogen bonding capability. Bioorg Chem  vol. 32, (1) 1-12. 10.1016/j.bioorg.2003.09.004

2002

Teh M-T, Wong S-T, Neill GW, Ghali LR, Philpott MP and Quinn AG (2002). FOXM1 is a downstream target of Gli1 in basal cell carcinomas. Cancer Res  vol. 62, (16) 4773-4780.
Philpott MP, NEILL GW, Leigh IM, Quinn AG, Ghali LR, Wong ST and Teh MT (2002). FOXM1 is a downstream target of Gli1 in basal cell carcinomas. Cancer Res.  vol. 62, (16) 4773-4780.
Teh M-T and Sugden D (2002). Desensitization of pigment granule aggregation in Xenopus leavis melanophores: melatonin degradation rather than receptor down-regulation is responsible. J Neurochem  vol. 81, (4) 719-727. 10.1046/j.1471-4159.2002.00885.x

2001

Teh MT and Sugden D (2001). An endogenous 5-HT7 receptor mediates pigment granule dispersion in Xenopus laevis melanophores. Brit J Pharmacol  vol. 132, (8) 1799-1808. 10.1038/sj.bjp.0703988

2000

Teh MT (2000). Cellular and Molecular Studies on Pigment-Granule Translocation in Xenopus Melanophores., Editors: Sugden DD.
Faust R, Garratt PJ, Jones R, Yeh LK, Tsotinis A, Panoussopoulou M, Calogeropoulou T, Teh MT and Sugden D (2000). Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1-a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles. J Med Chem  vol. 43, (6) 1050-1061. 10.1021/jm980684+

1999

Li PK, Sugden D, Teh MT, Chu GH and Witt-Enderby PA (1999). Synthesis and studies of irreversible melatonin receptor ligands. Abstr Pap Am Chem S  vol. 218, U962-U962.
Teh MT and Sugden D (1999). The putative melatonin receptor antagonist GR128107 is a partial agonist on Xenopus laevis melanophores. Brit J Pharmacol  vol. 126, (5) 1237-1245. 10.1038/sj.bjp.0702404

1998

Teh MT and Sugden D (1998). GR128107 is a partial melatonin receptor agonist on Xenopus laevis melanophores. Brit J Pharmacol  vol. 125, U39-U39.
Teh MT and Sugden D (1998). Comparison of the structure-activity relationships of melatonin receptor agonists and antagonists: Lengthening the N-acyl side-chain has differing effects on potency on Xenopus melanophores. N-S Arch Pharmacol  vol. 358, (5) 522-528. 10.1007/pl00005288
Davies DJ, Garratt PJ, Tocher DA, Vonhoff S, Davies J, Teh MT and Sugden D (1998). Mapping the melatonin receptor. 5. Melatonin agonists and antagonists derived from tetrahydrocyclopent[b]indoles, tetrahydrocarbazoles and hexahydrocyclohept[b]indoles. J Med Chem  vol. 41, (4) 451-467. 10.1021/jm970246n

Grants

Grants of specific relevance to Predictive in vitro Models
Development and validation of a molecular diagnostic tool for early diagnostic and personalized treatment of oral cancer
Costea DE, Mohamed NGA, Mohamed NMG, Nginamau ES, Suleiman A, Almahdi H, Uhlin-Hansen L, Dongre H, Jacobsen MR, Calenic B, Parajuli H, Sawant S, Muy-Teck T, Vaidya M, Johannessen AC, Neppelberg E, Sapkota D, Osman TA-H, Rajthala S, ahmed I and Teh M-T
Western Norway Regional Health Authority (01-01-2014 - 31-12-2016)
Summary