Dr Muy-Teck Teh

Muy-Teck Teh

Senior Lecturer

Centre for Oral Immunobiology & Regenerative Medicine, Institute
Queen Mary University of London
www.qmul.ac.uk/dentistry/people/profiles/drmuyteckteh.html
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Research

cancer spheroids, 3D in vitro culture model, chemoresistance, high-throughput 3D drug screening, transcriptome pattern recognition, mRNA biomarkers

Cancer Models

Interests

We are developing a high-throughput 3D cancer spheroid drug screening method to identify drugs that could counteract chemoresistance and identify transcriptome biomarker for predicting drug-gene interaction.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2025

A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial–mesenchymal transition and stemness in breast cancer
Usman S, Yeudall WA, Teh M-T, Ghloum F, Tummala H, Waseem A
Elife, Elife Sciences Publications, Ltd vol. 14 
21-07-2025
Membrane transporter progressive ankylosis protein homologue (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation, and ageing
James EN, Teh M-T, Li Y, Wagner-Bock C, Al-Khateeb ZF, Karen-Ng LP, Roberts T, Synchyshyn L et al.
Frontiers in Aging, Frontiers Media Sa vol. 6 
04-06-2025

2024

A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer
Usman S, Yeudall WA, Teh M-T, Ghloum F, Tummala H, Waseem A
In Cold Spring Harbor Laboratory 
15-11-2024
A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer

Elife, Elife Sciences Publications vol. 623301 
11-11-2024
Artificial Intelligence in Head and Neck Cancer: Innovations, Applications, and Future Directions
Pham TD, Teh M-T, Chatzopoulou D, Holmes S, Coulthard P
Current Oncology, Mdpi Ag vol. 31 (9), 5255-5290.  
06-09-2024
Membrane transporter Progressive Ankylosis Protein Homolog (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation and ageing
James EN, Teh M-T, Li Y, Wagner-Bock C, Al-Khateeb ZF, Karen-Ng LP, Roberts T, Synchyshyn L et al.
In Cold Spring Harbor Laboratory 
30-08-2024
Artificial Intelligence in Head and Neck Cancer: Innovations, Applications, and Future Directions
Pham TD, Teh M-T, Chatzopoulou D, Holmes S, Coulthard P
In Mdpi Ag 
09-08-2024
Site-Directed Mutagenesis to Mutate Multiple Residues in a Single Reaction

, Springer Us, 123-133.  
01-01-2024
Preparation and Use of shRNA for Knocking Down Specific Genes

, Springer Us, 55-72.  
01-01-2024

2023

Comparative Transcriptome Analysis Identifies Desmoglein-3 as a Potential Oncogene in Oral Cancer Cells
Wan H, Teh M-T, Mastroianni G, Ahmad US
Cells, Mdpi Ag vol. 12 (23), 2710-2710.  
26-11-2023
Comparative Transcriptome Analysis Identifies Desmoglein-3 as a Potential Oncogene in ORAL Cancer
Wan H, Teh M-T, Mastroianni G, Ahmad US
In Mdpi Ag 
25-09-2023
Identification of multidrug chemoresistant genes in head and neck squamous cell carcinoma cells

Molecular Cancer, Springer Science and Business Media Llc vol. 22 (1) 
04-09-2023
Efficacy of three antimicrobial mouthwashes in reducing SARS-CoV-2 viral load in the saliva of hospitalized patients: a randomized controlled pilot study
Perussolo J, Teh M-T, Gkranias N, Tiberi S, Petrie A, Cutino-Moguel M-T, Donos N
Scientific Reports, Springer Science and Business Media Llc vol. 13 (1) 
04-08-2023
Methods for diagnosing cancer (Version 2 - USA)
Teh M-T
USA Patent US20230133776. 
04-05-2023

2022

Transcriptome Analysis Reveals Vimentin-Induced Disruption of Cell–Cell Associations Augments Breast Cancer Cell Migration

Cells, Mdpi Ag vol. 11 (24), 4035-4035.  
13-12-2022
Transcriptome analysis reveals vimentin-induced disruption of cell-cell associations augments cancer cell migration

In Springer Science and Business Media Llc 
09-11-2022
Transcriptome analysis reveals vimentin-induced downregulation of cell-cell associations augments cancer cell migration
Usman S, Jamal A, Bushaala A, Waseem NH, Al-Dehlawi H, Yeudall A, Teh M-T, Tummala H et al.
In Springer Science and Business Media Llc 
03-11-2022
Vimentin Mediated Downregulation of Intercelluar Associations Augments Cancer Cell Migration

PER-IADR Oral Health Congress 2022 15 Sep 2022 - 17 Sep 2022. 
17-09-2022
Impact of N-Terminal Tags on De Novo Vimentin Intermediate Filament Assembly

International Journal of Molecular Sciences, Mdpi Ag vol. 23 (11), 6349-6349.  
06-06-2022
Molecular Signatures of Tumour and Its Microenvironment for Precise Quantitative Diagnosis of Oral Squamous Cell Carcinoma: An International Multi-Cohort Diagnostic Validation Study

Cancers, Mdpi Ag vol. 14 (6), 1389-1389.  
09-03-2022
Behavioral and Gene Regulatory Responses to Developmental Drug Exposures in Zebrafish
Mech AM, Merteroglu M, Sealy IM, Teh M-T, White RJ, Havelange W, Brennan CH, Busch-Nentwich EM
Frontiers in Psychiatry, Frontiers Media Sa vol. 12 
10-01-2022
Molecular Signatures of Tumour and Its Microenvironment for Precise Quantitative Diagnosis of Oral Squamous Cell Carcinoma: An International Multi-Cohort Diagnostic Validation Study

Cancers vol. 14 (6) 
01-01-2022

2021

Free Head Domain of Vimentin Is Crucial For Filament Assembly

Cell Bio Virtual 2021 EMBO Meeting American Society of Cell Biology 1 Dec 2021 - 10 Dec 2021. 
10-12-2021
Conservation of mechanisms regulating emotional-like responses on spontaneous nicotine withdrawal in zebrafish and mammals
Ponzoni L, Melzi G, Marabini L, Martini A, Petrillo G, Teh M-T, Torres-Perez JV, Morara S et al.
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Elsevier Bv vol. 111, 110334-110334.  
01-12-2021
Expression profile of SARS‐CoV‐2 cellular entry proteins in normal oral mucosa and oral squamous cell carcinoma
Sapkota D, Sharma S, Søland TM, Braz‐Silva PH, Teh M
Clinical and Experimental Dental Research, Wiley vol. 8 (1), 117-122.  
02-11-2021
Vimentin Is at the Heart of Epithelial Mesenchymal Transition (EMT) Mediated Metastasis

Cancers, Mdpi Ag vol. 13 (19), 4985-4985.  
05-10-2021
Methods for diagnosing cancer (Version 2)
Teh M-T
Patent WO2021013891. 
28-01-2021
Major Molecular Signaling Pathways in Oral Cancer Associated With Therapeutic Resistance

Frontiers in Oral Health, Frontiers Media Sa vol. 1 
25-01-2021

2020

Increased Response to 3,4-Methylenedioxymethamphetamine (MDMA) Reward and Altered Gene Expression in Zebrafish During Short- and Long-Term Nicotine Withdrawal
Ponzoni L, Teh M-T, Torres-Perez JV, Brennan CH, Braida D, Sala M
Molecular Neurobiology, Springer Science and Business Media Llc vol. 58 (4), 1650-1663.  
24-11-2020
RASSF1A inhibits PDGFB-driven malignant phenotypes of nasopharyngeal carcinoma cells in a YAP1-dependent manner
Liang Y-Y, Deng X-B, Lin X-T, Jiang L-L, Huang X-T, Mo Z-W, Yuan Y-W, Teh M-T
Cell Death &Amp; Disease, Springer Science and Business Media Llc vol. 11 (10) 
14-10-2020
Identification of slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour
García-González J, Brock AJ, Parker MO, Riley RJ, Joliffe D, Sudwarts A, Teh M-T, Busch-Nentwich EM et al.
Elife, Elife Sciences Publications, Ltd vol. 9 
25-03-2020
Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes

Scientific Reports, Springer Science and Business Media Llc vol. 10 (1) 
16-03-2020
A Novel Diagnostic Tool for Cancer Detection
Teh M-T
Scientia, Science Diffusion Ltd 
01-01-2020

2019

Evidence for the Desmosomal Cadherin Desmoglein-3 in Regulating YAP and Phospho-YAP in Keratinocyte Responses to Mechanical Forces
Uttagomol J, Ahmad US, Rehman A, Huang Y, Laly AC, Kang A, Soetaert J, Chance R et al.
International Journal of Molecular Sciences, Mdpi Ag vol. 20 (24), 6221-6221.  
10-12-2019
The transcription factor FOXM1 regulates the balance between proliferation and aberrant differentiation in head and neck squamous cell carcinoma
Roh V, Hiou‐Feige A, Misetic V, Rivals J, Sponarova J, Teh M, Ferreira Lopes S, Truan Z et al.
The Journal of Pathology, Wiley vol. 250 (1), 107-119.  
03-12-2019
qMIDS: A Digital Diagnostic Test for Oral Cancer

British Journal of Oral and Maxillofacial Surgery, Elsevier Bv vol. 57 (10), e86-e87.  
01-12-2019
The desmosomal cadherin Desmoglein-3 regulates YAP and phospho-YAP in keratinocyte responses to mechanical forces
Uttagomol J, Ahmad US, Rehman A, Huang Y, Laly AC, Kang A, Soetaert J, Chance R et al.
In Cold Spring Harbor Laboratory 
01-11-2019
The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53
Rehman A, Cai Y, Hünefeld C, Jedličková H, Huang Y, Teck Teh M, Sharif Ahmad U, Uttagomol J et al.
Cell Death &Amp; Disease, Springer Science and Business Media Llc vol. 10 (10) 
03-10-2019
Clinical correlation of opposing molecular signatures in head and neck squamous cell carcinoma

Bmc Cancer, Springer Science and Business Media Llc vol. 19 (1) 
23-08-2019
The monoclonal antibody EPR1614Y against the stem cell biomarker keratin K15 lacks specificity and reacts with other keratins

Scientific Reports, Springer Science and Business Media Llc vol. 9 (1) 
13-02-2019

2018

Identification ofSlit3as a locus affecting nicotine preference in zebrafish and human smoking behaviour
García-González J, Brock AJ, Parker MO, Riley R, Jolliffe D, Sudwarts A, Teh M-T, Busch-Nentwich EM et al.
In Cold Spring Harbor Laboratory 
26-10-2018
The Pemphigus Vulgaris antigen desmoglein-3 suppresses p53 function via the YAP-Hippo pathway
Rehman A, Cai Y, Hünefeld C, Jedličková H, Huang Y, Teh MT, Uttagomol J, Kang A et al.
In Cold Spring Harbor Laboratory 
25-08-2018
Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation
Qadir F, Aziz MA, Sari CP, Ma H, Dai H, Wang X, Raithatha D, Da Silva LGL et al.
Molecular Cancer, Springer Science and Business Media Llc vol. 17 (1) 
16-07-2018
Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation

Molecular Cancer vol. 17 
01-01-2018

2017

GLI2 Is a Regulator of β-Catenin and Is Associated with Loss of E-Cadherin, Cell Invasiveness, and Long-Term Epidermal Regeneration
Pantazi E, Gemenetzidis E, Teh M-T, Reddy SV, Warnes G, Evagora C, Trigiante G, Philpott MP
Journal of Investigative Dermatology, Elsevier Bv vol. 137 (8), 1719-1730.  
01-08-2017

2016

Integrin α11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression
Parajuli H, Teh M, Abrahamsen S, Christoffersen I, Neppelberg E, Lybak S, Osman T, Johannessen AC et al.
Journal of Oral Pathology &Amp; Medicine, Wiley vol. 46 (4), 267-275.  
04-10-2016
Independent evaluation of a FOXM1-based quantitative malignancy diagnostic system (qMIDS) on head and neck squamous cell carcinomas
Ma H, Dai H, Duan X, Tang Z, Liu R, Sun K, Zhou K, Chen H et al.
Oncotarget, Impact Journals, Llc vol. 7 (34), 54555-54563.  
09-07-2016
Oral Cancer Biomarkers: Is it a Meaningless Game?
Teh M-T
Dentistry - Open Journal, Openventio Publishers vol. 3 (1), e1-e3.  
17-06-2016
S100A16 Functions as a Tumor Suppressor Protein in Oral Squamous Cell Carcinoma
Sapkota D, Bruland O, Parajuli H, Osman T, Teh MT, Johannessen A, Costea D
 
01-03-2016

2015

Developmental role of acetylcholinesterase in impulse control in zebrafish
Parker MO, Brock AJ, Sudwarts A, Teh M-T, Combe FJ, Brennan CH
Frontiers in Behavioral Neuroscience, Frontiers Media Sa vol. 9 
16-10-2015
S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma
Sapkota D, Bruland O, Parajuli H, Osman TA, Teh M-T, Johannessen AC, Costea DE
Bmc Cancer, Springer Science and Business Media Llc vol. 15 (1) 
09-09-2015
Is Salivary Exosome the Answer to Early Detection of Oral Cancer?
Teh M-T
Dentistry - Open Journal, Openventio Publishers vol. 2 (2), e3-e4.  
25-08-2015
Can Challenges of Oral Cancer Diagnosis be Resolved?
Teh M-T
Dental Health: Current Research, Omics Publishing Group vol. 01 (01) 
01-01-2015
HOXA7 suppresses keratinocyte differentiation via PKC/AP-1 pathway

 
01-01-2015

2014

The utility of zebrafish to study the mechanisms by which ethanol affects social behavior and anxiety during early brain development
Parker MO, Annan LV, Kanellopoulos AH, Brock AJ, Combe FJ, Baiamonte M, Teh MT, Brennan CH
Progress in Neuro Psychopharmacology and Biological Psychiatry vol. 55, 94-100.  
03-12-2014
The utility of zebrafish to study the mechanisms by which ethanol affects social behavior and anxiety during early brain development
Parker MO, Annan LV, Kanellopoulos AH, Brock AJ, Combe FJ, Baiamonte M, Teh M-T, Brennan CH
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Elsevier Bv vol. 55, 94-100.  
01-12-2014
Moderate alcohol exposure during early brain development increases stimulus‐response habits in adulthood
Parker MO, Evans AM, Brock AJ, Combe FJ, Teh M, Brennan CH
Addiction Biology, Wiley vol. 21 (1), 49-60.  
19-08-2014
Changes in Abundance of Oral Microbiota Associated with Oral Cancer
Schmidt BL, Kuczynski J, Bhattacharya A, Huey B, Corby PM, Queiroz ELS, Nightingale K, Kerr AR et al.
Plos One, Public Library of Science (Plos) vol. 9 (6), e98741-e98741.  
02-06-2014
GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh M-T et al.
Cell Death &Amp; Disease, Springer Science and Business Media Llc vol. 5 (1), e1028-e1028.  
30-01-2014

2013

Identification of FOXM1‐induced epigenetic markers for head and neck squamous cell carcinomas

Cancer, Wiley vol. 119 (24), 4249-4258.  
01-10-2013
Keratin K15 as a Biomarker of Epidermal Stem Cells

International Journal of Molecular Sciences, Mdpi Ag vol. 14 (10), 19385-19398.  
25-09-2013
GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao E, Ikram M, Neill G et al.
 
01-01-2013

2012

Exploiting FOXM1‐orchestrated molecular network for early squamous cell carcinoma diagnosis and prognosis

International Journal of Cancer, Wiley vol. 132 (9), 2095-2106.  
25-10-2012
Cells Brainwashed by FOXM1: Do they have Potential as Biomarkers of Cancer?
Teh M-T
Biomarkers in Medicine, Informa Uk Limited vol. 6 (4), 499-501.  
01-08-2012
Two Mechanisms Regulate Keratin K15 Expression In Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signalling

Plos One, Public Library of Science (Plos) vol. 7 (6), e38599-e38599.  
27-06-2012
FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squamous Cell Carcinoma

Plos One, Public Library of Science (Plos) vol. 7 (3), e34329-e34329.  
26-03-2012
Increased secretion of tissue inhibitors of metalloproteinases 1 and 2 (TIMPs ‐1 and ‐2) in fibroblasts are early indictors of oral sub‐mucous fibrosis and ageing

Journal of Oral Pathology &Amp; Medicine, Wiley vol. 41 (6), 454-462.  
03-03-2012
Methods for Diagnosing Cancer (Version 1)
Teh MT
Patent WO2012013931. 
02-02-2012
FOXM1 coming of age: time for translation into clinical benefits?
Teh M-T
Frontiers in Oncology, Frontiers Media Sa vol. 2 
01-01-2012

2011

Chapter 14: Initiation of Human Tumourigenesis: Upregulation of FOXM1 Transcription Factor.
TEH M
In Stem Cells and Cancer Stem Cells,Volume 3, Springer Verlag 149-154.  
22-11-2011
Initiation of Human Tumourigenesis: Upregulation of FOXM1 Transcription Factor
Teh M-T
In Stem Cells and Cancer Stem Cells,Volume 3, Springer Netherlands 149-154.  
21-10-2011
Correction: Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1

Cancer Research, American Association For Cancer Research (Aacr) vol. 71 (1), 290-290.  
01-01-2011
A molecular study of desmosomes identifies a desmoglein isoform switch in head and neck squamous cell carcinoma
Teh MT, Parkinson EK, Thurlow JK, Liu F, Fortune F, Wan H
J Oral Pathol Med vol. 40 (1), 67-76.  
01-01-2011

2010

Desmoglein 3, via an Interaction with E-cadherin, Is Associated with Activation of Src
Tsang SM, Liu L, Teh MT, Wheeler A, Grose R, Hart IR, Garrod DR, Fortune F et al.
Plos One vol. 5 (12) 
03-12-2010
Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1
Gemenetzidis E, Costea DE, Parkinson EK, Waseem A, Wan H, Teh MT
Cancer Research, American Association For Cancer Research vol. 22 (70), 9515-9526.  
15-11-2010
Downstream targets of FOXM1: CEP55 and HELLS are cancer progression markers of head and neck squamous cell carcinoma

Oral Oncol vol. 46 (7), 536-542.  
01-07-2010
EPS8 upregulates FOXM1 expression, enhancing cell growth and motility
Wang H, Teh M-T, Ji Y, Patel V, Firouzabadian S, Patel AA, Gutkind JS, Yeudall WA
Carcinogenesis, Oxford University Press (Oup) vol. 31 (6), 1132-1141.  
29-03-2010
Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes
Teh MT, Gemenetzidis E, Chaplin T, Young BD, Philpott MP
Mol Cancer vol. 9 
26-02-2010
Overexpression of GLI2 in human keratinocytes results in resistance to ultraviolet B-induced apoptosis and increased chromosomal instability
Pantazi E, Trigiante G, Warnes G, Gemenetzidis E, Teh M-T, Ikram M, Shan L, Lu YJ et al.
 
01-01-2010
Novel role for human desmoglein 3 in regulating E-cadherin mediated adherens junctions through Src family kinase activation
Tsang S, Liu L, Teh M, Wheeler A, Piper K, Grose R, Hart I, Garrod D et al.
 
01-01-2010

2009

FOXM1 Upregulation Is an Early Event in Human Squamous Cell Carcinoma and it Is Enhanced by Nicotine during Malignant Transformation

Plos One vol. 4 (3) 
16-03-2009
Overexpression of GLI2 in human keratinocytes results in polyploidy and resistance to ultraviolet B-induced apoptosis
Pantazi E, Trigianti G, Warnes G, Gemenetzidis E, Teh M-T, Philpott MP
 
01-01-2009

2008

Fingerprinting genomic instability in oral submucous fibrosis

J Oral Pathol Med vol. 37 (7), 430-436.  
01-08-2008
Upregulation of HIF‐1α in malignant transformation of oral submucous fibrosis

Journal of Oral Pathology &Amp; Medicine, Wiley vol. 37 (6), 372-377.  
21-01-2008
An altered keratinocyte phenotype in oral submucous fibrosis: correlation of keratin K17 expression with disease severity

Journal of Oral Pathology &Amp; Medicine, Wiley vol. 37 (4), 211-220.  
19-01-2008

2007

Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis
Purdie KJ, Lambert SR, Teh MT, Chaplin T, Molloy G, Raghavan M, Kelsell DR, Leigh IM et al.
Gene Chromosome Canc vol. 46 (7), 661-669.  
01-07-2007
7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: Effect of substituents on potency and binding affinity
Faust R, Garratt PJ, Trujillo Pérez MA, Piccio VJ-D, Madsen C, Stenstrøm A, Frølund B, Davidson K et al.
Bioorganic &Amp; Medicinal Chemistry, Elsevier Bv vol. 15 (13), 4543-4551.  
01-07-2007
P245 Up regulation of HIF-1a in the progression and malignant transformation of oral submucous fibrosis

Oral Oncology Supplement, Elsevier Bv vol. 2 (1), 204-205.  
01-05-2007
Role for WNT16B in human epidermal keratinocyte proliferation and differentiation
Teh M-T, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM et al.
Journal of Cell Science, The Company of Biologists vol. 120 (5), 917-917.  
01-03-2007
Role for WNT16B in human epidermal keratinocyte proliferation and differentiation
Teh MT, Blaydon D, Ghali LR, Edmunds S, Pantazi E, Barnes MR, Leigh IM, Kelsell DP et al.
J Cell Sci vol. 120 (2), 330-339.  
15-01-2007
Up regulation of HIF-1α in the progression and malignant transformation of oral submucous fibrosis

 
01-01-2007
Role for WNT16B in human epidermal keratinocyte proliferation and differentiation (vol 120, pg 330, 2007)
Teh M-T, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM et al.
Journal of Cell Science vol. 120 (5), 917-917.  
01-01-2007
Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis
Purdie K, Lambert S, Teh M, Chaplin T, Molloy G, Raghavan M, Kelsell DP, Leigh IM et al.
 
01-01-2007

2006

The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia
Blaydon DC, Ishii Y, O'Toole EA, Unsworth HC, Teh MT, Ruschendorf F, Sinclair C, Hopsu-Havu VK et al.
Nat Genet vol. 38 (11), 1245-1247.  
01-11-2006
Mapping the Melatonin Receptor. 7. Subtype Selective Ligands Based on β-SubstitutedN-Acyl-5-methoxytryptamines and β-SubstitutedN-Acyl-5-methoxy-1-methyltryptamines
Tsotinis A, Vlachou M, Papahatjis DP, Calogeropoulou T, Nikas SP, Garratt PJ, Piccio V, Vonhoff S et al.
Journal of Medicinal Chemistry, American Chemical Society (Acs) vol. 49 (12), 3509-3519.  
09-05-2006
R-spondin 4 (RSPO4), a novel secreted protein implicated in Wnt signalling, is mutated in inherited anonychia
Blaydon DC, Ishii Y, O'Toole EA, Teh MT, Hopsu-Havu VK, Moss C, Ruschendorf F, Wajid M et al.
 
01-01-2006
Allelic imbalances and chromosome 9p microdeletion demonstrated in cutaneous squamous cell carcinomas using single nucleotide polymorphism microarray analysis
Purdie K, Teh M, Harwood C, Young B, Proby C, Leigh I
 
01-01-2006

2005

Genomewide single nucleotide polymorphism microarray mapping in basal cell carcinomas unveils uniparental disomy as a key somatic event
Teh MT, Blaydon D, Chaplin T, Foot NJ, Skoulakis S, Raghavan M, Harwood CA, Proby CM et al.
Cancer Res vol. 65 (19), 8597-8603.  
01-10-2005
Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis
Kelsell DP, Norgett EE, Unsworth H, Teh MT, Cullup T, Mein CA, Dopping-Hepenstal PJ, Dale BA et al.
Am J Hum Genet vol. 76 (5), 794-803.  
01-05-2005
Genome-wide SNP microarray mapping in basal cell carcinomas unveils uniparental dismay as a key somatic event
Blaydon DC, Teh M, Foot NJ, Philpott MP, Harwood C, Proby C, Young BD, Kelsell DP
 
01-01-2005
The Human forkhead transcription factor FOXM1B enhances DNA repair and suppresses UVB-induced apoptosis
Teh MT, Quinn AG, Philpott MP
 
01-01-2005
FOXM1b activates DNA repair and suppresses UVB-induced apoptosis in human keratinocytes
Teh M, Quinn AG, Philpott MP
 
01-01-2005
Mutations in ABCA12 underlie harlequin ichthyosis
Kelsell DP, Norgett E, Unsworth H, Teh M, Cullop T, Dale B, Leigh IM, Eady RA et al.
 
01-01-2005
Clinical and molecular features of Harlequin ichthyosis
Kelsell DP, Norgett EE, Unsworth H, Teh MT, Cullup T, Mein CA, Dopping-Hepenstal PJ, Kennedy CT et al.
 
01-01-2005

2004

Melatonin, melatonin receptors and melanophores: A moving story
Sugden D, Davidson K, Hough KA, Teh MT
Pigm Cell Res vol. 17 (5), 454-460.  
01-10-2004
Binding affinity and biological activity of oxygen and sulfur isosteres at melatonin receptors as a function of their hydrogen bonding capability
Davies DJ, Faust R, Garratt PJ, Marivingt-Mounir C, Kathryn Davidson, Teh M-T, Sugden D
Bioorganic Chemistry, Elsevier Bv vol. 32 (1), 1-12.  
01-02-2004

2002

FOXM1 is a downstream target of Gli1 in basal cell carcinomas
Teh MT, Wong ST, Neill GW, Ghali LR, Philpott MP, Quinn AG
Cancer Res vol. 62 (16), 4773-4780.  
15-08-2002
Desensitization of pigment granule aggregation in Xenopus leavis melanophores: melatonin degradation rather than receptor down-regulation is responsible
Teh MT, Sugden D
J Neurochem vol. 81 (4), 719-727.  
01-05-2002
FOXM1 is a downstream target of hedgehog signalling in basal cell carcinomas (BCC)
Teh MT, Wong ST, Neill G, Ghali L, Philpott M, Quinn A
 
01-01-2002

2001

An endogenous 5‐HT7 receptor mediates pigment granule dispersion in Xenopus laevis melanophores
Teh M, Sugden D
British Journal of Pharmacology, Wiley vol. 132 (8), 1799-1808.  
01-04-2001

2000

Cellular and Molecular Studies on Pigment-Granule Translocation in Xenopus Melanophores
Teh MT
 
01-06-2000
Mapping the Melatonin Receptor. 6. Melatonin Agonists and Antagonists Derived from 6H-Isoindolo[2,1-a]indoles, 5,6-Dihydroindolo[2,1-a]isoquinolines, and 6,7-Dihydro-5H-benzo[c]azepino[2,1-a]indoles
Faust R, Garratt PJ, Jones R, Yeh L-K, Tsotinis A, Panoussopoulou M, Calogeropoulou T, Teh M-T et al.
Journal of Medicinal Chemistry, American Chemical Society (Acs) vol. 43 (6), 1050-1061.  
01-03-2000

1999

The putative melatonin receptor antagonist GR128107 is a partial agonist on Xenopus laevis melanophores
Teh M, Sugden D
British Journal of Pharmacology, Wiley vol. 126 (5), 1237-1245.  
01-03-1999
Synthesis and studies of irreversible melatonin receptor ligands.
Li PK, Sugden D, Teh MT, Chu GH, Witt-Enderby PA
Abstracts of Papers of The American Chemical Society vol. 218, U962-U962.  
01-01-1999
Design of subtype selective melatonin receptor agonists and antagonists
Sugden D, Yeh L-K, Teh M-T
 
01-01-1999

1998

Comparison of the structure-activity relationships of melatonin receptor agonists and antagonists: lengthening the N-acyl side-chain has differing effects on potency on Xenopus melanophores
Teh M-T, Sugden D
Naunyn-Schmiedeberg's Archives of Pharmacology, Springer Science and Business Media Llc vol. 358 (5), 522-528.  
02-11-1998
Mapping the Melatonin Receptor. 5. Melatonin Agonists and Antagonists Derived from Tetrahydrocyclopent[b]indoles, Tetrahydrocarbazoles and Hexahydrocyclohept[b]indoles
Davies DJ, Garratt PJ, Tocher DA, Vonhoff S, Davies J, Teh M-T, Sugden D
Journal of Medicinal Chemistry, American Chemical Society (Acs) vol. 41 (4), 451-467.  
27-01-1998
GR128107 is a partial melatonin receptor agonist on Xenopus laevis melanophores
Teh MT, Sugden D
British Journal of Pharmacology vol. 125, U39-U39.  
01-01-1998

1997

Melatonin receptor pharmacology: toward subtype specificity
Sugden D, Pickering H, Teh M, Garratt PJ
 
01-11-1997

Grants

solid heart iconGrants of specific relevance to Predictive in vitro Models
solid heart iconThe molecular mechanisms underlying the tumour-determined immune cell infiltrate in oral squamous cell carcinoma
Adrian Biddle and Muy-Teck Teh
£298,338 MCSBHT Medical College of St Bartholomew's Hospital Trust
01-09-2021 - 31-01-2026

bullet iconUsing novel AI tools to improve the diagnostic accuracy of qMIDS- oral cancer early diagnostic tool
Muy-Teck Teh
£22,313 Curenetics Limited
08-05-2023 - 07-05-2024
bullet iconqMIDS head and neck tumour identification technology
Muy-Teck Teh
£59,978 Guizhou Medical University (GMU)
01-05-2019 - 30-04-2024