Publications

Publications of specific relevance to Predictive in vitro Models
2023

Smith C, Abdullah M, Hassan S, Qamar Y, Hall C, Maitra S, Maharaj A, Mariela MRL, Read J,
Chan L,
Metherell L and Musa S (2023).
Genetic Aetiology of Primary Adrenal Insufficiency in Sudan. Bioscientifica Endocrine Abstracts 10.1530/endoabs.90.p560
Smith CJ,
Chan L and
Metherell LA (2023).
769 Reduced expression of PPOX, the variegate porphyria gene, causes intrinsic pathological changes to keratinocytes. Elsevier Journal of Investigative Dermatology vol. 143, (5)
10.1016/j.jid.2023.03.778
Baksh RA, Pape SE,
Chan LF, Aslam AA, Gulliford MC, Strydom A and GO-DS21 Consortium (2023).
Multiple morbidity across the lifespan in people with Down syndrome or intellectual disabilities: a population-based cohort study using electronic health records. Lancet Public Health 10.1016/S2468-2667(23)00057-9
Hasenmajer V, Ferrigno R, Minnetti M, Pellegrini B, Isidori AM, Lenzi A, Salerno M, Cappa M,
Chan L, De Martino MC and Savage MO (2023).
Rare forms of genetic paediatric adrenal insufficiency: Excluding congenital adrenal hyperplasia. Reviews in Endocrine and Metabolic Disorders vol. 24, (2) 345-363.
10.1007/s11154-023-09784-7
Parry CM,
Chan LF, Carr DF and Hawcutt DB (2023).
Platelet-derived growth factor D expression in adrenal cells is modulated by corticosteroids: putative role in adrenal suppression. Pediatr Res vol. 93, (1) 97-101.
10.1038/s41390-022-02094-92022
Chan L, Smith C, Read J, Hall C, Maharaj A, Ramirez LM, Qamar Y, Hughes C, Clark A, Musa S, Prasad R and
Metherell L (2022).
RF33 | PSAT69 A Combined Candidate Gene/Whole Exome Sequencing Approach Permits a Rapid Genetic Diagnosis for >81% Individuals with Primary Adrenal Insufficiency. The Endocrine Society Journal of The Endocrine Society vol. 6, (Suppl 1) a140-a141.
10.1210/jendso/bvac150.286
Chan L (2022).
Identification of a novel specific small-molecule melanocortin-2-receptor antagonist. Bioscientifica Endocrine Connections vol. 11, (12)
10.1530/EC-22-0338
Aslam A, Baksh A, Pape S, Consortium G-D, Strydom A, Gulliford M and
Chan L (2022).
Diabetes and obesity in down syndrome across the lifespan: a retrospective cohort study using UK electronic health records. Endocrine Abstracts 10.1530/endoabs.85.oc9.3
Maitra S, Smith C, Hall C, Read J, Maharaj AV, Mariela MRL, Qamar Y, Prasad R,
Chan LF and
Metherell LA (2022).
The lack of genotype: phenotype correlations in rare causes of primary adrenal insufficiency highlights the need for genetic testing. Bioscientifica Endocrine Abstracts 10.1530/endoabs.85.oc5.5
Aslam A, Baksh A, Pape S, Strydom A, Gulliford M and Chan L (2022).
Diabetes and obesity in Down Syndrome across the lifespan: a retrospective cohort study using UK electronic health records. American Diabetes Association Diabetes Care 10.2337/dc22-0482
Baksh RA, Strydom A, Pape SE,
Chan LF and Gulliford MC (2022).
Susceptibility to COVID-19 Diagnosis in People with Down Syndrome Compared to the General Population: Matched-Cohort Study Using Primary Care Electronic Records in the UK. Journal of General Internal Medicine vol. 37, (8) 2009-2015.
10.1007/s11606-022-07420-9
Smith C, Read J, Hall C, Maharaj A, Marroquin RL, Qamar Y, Hughes C, Clark A, Prasad R,
Chan L, Musa S and
Metherell L (2022).
A rapid genetic diagnosis for >80% individuals with non-CAH Primary Adrenal Insufficiency is achievable by candidate gene sequencing combined with WES. Bioscientifica Endocrine Abstracts 10.1530/endoabs.81.rc2.1
Perez-Ternero C, Aubdool AA, Makwana R,
Sanger GJ, Stimson RH,
Chan LF, Moyes AJ and
Hobbs AJ (2022).
C-type natriuretic peptide is a pivotal regulator of metabolic homeostasis. Proceedings of The National Academy of Sciences of The United States of America vol. 119, (13)
10.1073/pnas.2116470119
Baksh RA, Pape SE,
Chan LF, Aslam AA, Gulliford MC, Strydom A and Consortium G-D (2022).
Multiple Morbidity Across the Lifespan in People with Down Syndrome or Intellectual Disability: Population-Based Cohort Study Using Electronic Health Records. Elsevier The Lancet Public Health 10.2139/ssrn.42827212021

Smith C, Maharaj A, Qamar Y, Read J, Williams J, Marimuthu V,
Chan L and
Metherell L (2021).
In vitro splicing assay proves the pathogenicity of intronic variants in MRAP. Bioscientifica Endocrine Abstracts 10.1530/endoabs.77.p134
H I, O D, F F, V C, AK G, NJ R, J B, V P, Y P, LF C, D B-Z, PJ M, Y N and M S-B (2021).
Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signalling. 10.1530/ey.18.11.2
Degtjarik O, Israeli H,
Chan LF, Ben-Zvi D, Niv MY, McCormick PJ and Shalev-Benami M (2021).
To eat or not to eat: cryo-EM structure of melanocortin receptor 4 reveals mechanism of a 'hunger switch' initiating satiety signalling. Acta Crystallographica Section a: Foundations and Advances vol. 77, (a2) c480-c480.
10.1107/s0108767321092060
Buonocore F, Maharaj A, Qamar Y, Koehler K, Suntharalingham JP,
Chan LF, Ferraz-De-Souza B, Hughes CR, Lin L, Prasad R, Allgrove J, Andrews ET, Buchanan CR, Cheetham TD, Crowne EC, Davies JH, Gregory JW, Hindmarsh PC, Hulse T, Krone NP, Shah P, Shaikh MG, Roberts C, Clayton PE, Dattani MT, Thomas NS, Huebner A, Clark AJ,
Metherell LA and Achermann JC (2021).
Genetic Analysis of Pediatric Primary Adrenal Insufficiency of Unknown Etiology: 25 Years' Experience in the UK. Journal of The Endocrine Society vol. 5, (8)
10.1210/jendso/bvab086
Israeli H, Degtjarik O, Fierro F, Chunilal V, Gill AK, Roth NJ, Botta J, Prabahar V, Peleg Y,
Chan LF, Ben-Zvi D,
McCormick PJ, Niv MY and Shalev-Benami M (2021).
Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling. Science vol. 372, (6544) 808-814.
10.1126/science.abf7958
Smith C, Maharaj AV, Qamar Y, Read J, Williams J,
Chan L, Marimuthu V and
Metherell L (2021).
In Vitro Splicing Assay Proves the Pathogenicity of Intronic Variants in MRAP. Journal of The Endocrine Society vol. 5, (Suppl 1) a85-a86.
10.1210/jendso/bvab048.172
Maudhoo A, Maharaj A, Buonocore F, Martos-Moreno GA, Argente J, Achermann JC,
Chan LF and
Metherell LA (2021).
Missplicing due to a synonymous, t96= exonic substitution in the t-box transcription factor tbx19 resulting in isolated acth deficiency. Endocrinology, Diabetes and Metabolism Case Reports vol. 2021, (1)
10.1530/EDM-21-01282020

Maharaj A, Williams J, Bradshaw T, Güran T, Braslavsky D, Casas J,
Chan LF,
Metherell LA and Prasad R (2020).
Sphingosine-1-phosphate lyase (SGPL1) deficiency is associated with mitochondrial dysfunction. J Steroid Biochem Mol Biol vol. 202,
10.1016/j.jsbmb.2020.1057302019

Qamar Y, Maharaj A,
Chan L, AbdulBagi S, Abdullah M and
Metherell L (2019).
Rare causes of primary adrenal insufficiency (PAI) in children from Sudan. Bioscientifica Endocrine Abstracts 10.1530/endoabs.66.oc5.9
Smith C, Maharaj A, Prasad R, Hughes C, Qamar Y, Clark A,
Chan L and
Metherell L (2019).
Twenty-five years of familial glucocorticoid deficiency: genotypic and phenotypic variability. Bioscientifica Endocrine Abstracts 10.1530/endoabs.65.p48
Qamar Y, Maharaj A,
Chan L, Deeb A and
Metherell L (2019).
Splice-site mutations in the melanocortin-2 receptor accessory protein that lead to early-onset familial glucocorticoid deficiency type 2. Bioscientifica Endocrine Abstracts 10.1530/endoabs.65.cc2
Novoselova TV, King PJ, Guasti L,
Metherell LA, Clark AJL and
Chan LF (2019).
ACTH signalling and adrenal development: Lessons from mouse models. Endocrine Connections vol. 8, (7) R122-R130.
10.1530/EC-19-0190
Maharaj A, Maudhoo A,
Chan LF, Novoselova T, Prasad R,
Metherell LA and Guasti L (2019).
Isolated glucocorticoid deficiency: Genetic causes and animal models. Journal of Steroid Biochemistry and Molecular Biology vol. 189, 73-80.
10.1016/j.jsbmb.2019.02.0122018

Maudhoo A, Maharaj A, Buonocore F, Martos-Moreno GA, Argente J, Achermann J,
Chan L and
Metherell L (2018).
Missplicing due to a silent exonic substitution in the T-box transcription factor TBX19 resulting in Isolated ACTH deficiency. Bioscientifica Endocrine Abstracts 10.1530/endoabs.59.cc2
Novoselova TV, Hussain M, King PJ, Guasti L,
Metherell LA, Charalambous M, Clark AJL and
Chan LF (2018).
MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation. Faseb Journal vol. 32, (11) 6186-6196.
10.1096/fj.201701274RR
Chan L, Hussain M, Forfar R, Khurana P, Cook J, Lewis S, McIver E, Jerman J, Taylor D and Clark A (2018).
Identification and characterisation of a small-molecule ACTH receptor/Melanocortin-2-receptor antagonist. Endocrine Abstracts 10.1530/endoabs.58.oc4.4
Bruschetta G, Kim JD, Diano S and
CHAN L (2018).
Overexpression of Melanocortin 2 Receptor Accessory Protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure. Elsevier Molecular Metabolism 10.1016/j.molmet.2018.09.010
Novoselova TV,
Chan LF and Clark AJL (2018).
Pathophysiology of melanocortin receptors and their accessory proteins. Best Pract Res Clin Endocrinol Metab vol. 32, (2) 93-106.
10.1016/j.beem.2018.02.0022017

Clark AJL and
Chan LF (2017).
Promiscuity among the MRAPs. Bioscientifica Journal of Molecular Endocrinology vol. 58, (3) F1-F4.
10.1530/JME-17-00022016
CHAN L (2016).
A central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity. National Academy of Sciences Proceedings of The National Academy of Sciences of Usa 10.1073/pnas.1607464113
Clark AJ, Forfar R, Hussain M, Jerman J, McIver E, Taylor D and
Chan L (2016).
ACTH Antagonists. Frontiers Media Frontiers in Endocrinology vol. 7,
10.3389/fendo.2016.00101
Novoselova TV, Larder R, Rimmington D, Lelliott C, Wynn E, Gorrigan RJ, Tate P, Guasti L, Sanger Mouse Genetics Project T, O'Rahilly S, Clark AJL, Logan DW, Coll AP and
Chan LF (2016).
Loss of Mrap2 is associated with Sim 1 deficiency and increased circulating cholesterol. Journal of Endocrinology JOE-16-0057-JOE-16-0057.
10.1530/JOE-16-00572015

Buonocore F,
Chan L, Achermann J and
Metherell L (2015).
Molecular diagnosis of patients with adrenal insufficiency using a targeted custom Haloplex next-generation sequencing panel. Bioscientifica Endocrine Abstracts 10.1530/endoabs.38.oc3.1
Chan LF, Campbell DC, Novoselova TV, Clark AJL and
Metherell LA (2015).
Whole-Exome Sequencing in the Differential Diagnosis of Primary Adrenal Insufficiency in Children. Frontiers in Endocrinology vol. 6,
10.3389/fendo.2015.00113
Novoselova TV, Rath SR, Carpenter K, Pachter N, Dickinson JE, Price G,
Chan LF, Choong CS and
Metherell LA (2015).
NNT Pseudoexon Activation as a Novel Mechanism for Disease in Two Siblings With Familial Glucocorticoid Deficiency. Endocrine Society Journal of Clinical Endocrinology & Metabolism vol. 100, (2) E350-E354.
10.1210/jc.2014-3641
Jackson DS, Ramachandrappa S, Clark AJ and
Chan LF (2015).
Melanocortin receptor accessory proteins in adrenal disease and obesity. Frontiers in Neuroscience vol. 9, (MAY)
10.3389/fnins.2015.002132014

Novoselova T, Larder R, Rimmington D, Lelliott C, Wynn E, O'Rahilly S, Clark A, Logan D, Coll A and
Chan L (2014).
Melanocortin 2 receptor accessory protein 2 (Mrap2) regulates hypothalamic melanocortin-4-receptor trafficking in vivo. Endocrine Abstracts 10.1530/endoabs.36.p60
Chan L, Novoselova T, Rath S, Carpenter K, Pachter N, Price G, Dickinson J, Choong C and
Metherell L (2014).
cDNA analysis reveals NNT pseudoexon activation in two siblings with familial glucocorticoid deficiency. Bioscientifica Endocrine Abstracts 10.1530/endoabs.36.p4
Novoselova T, Spoudeas H, Huebner A, Cheetham T,
Chan L and
Metherell L (2014).
Varied clinical presentations of six patients with mutations in CYP11A1 encoding the cholesterol side-chain cleavage enzyme, P450scc. Bioscientifica Endocrine Abstracts 10.1530/endoabs.36.p12
Prasad R,
Chan LF, Hughes CR, Kaski JP, Kowalczyk JC, Savage MO, Peters CJ, Nathwani N, Clark AJL, Storr HL and
Metherell LA (2014).
Thioredoxin Reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD). J Clin Endocrinol Metab vol. 99, (8) E1556-E1563.
10.1210/jc.2013-38442013

Asai M, Ramachandrappa S, Joachim M, Shen Y, Zhang R, Nuthalapati N, Ramanathan V, Strochlic DE, Ferket P, Linhart K, Ho C, Novoselova TV, Garg S, Ridderstråle M, Marcus C, Hirschhorn JN, Keogh JM, O’Rahilly S,
CHAN L, Clark AJ, Farooqi IS and Majzoub JA (2013).
Loss of Function of the Melanocortin 2 Receptor Accessory Protein 2 Is Associated with Mammalian Obesity. American Association For The Advancement of Science Science vol. 341, (6143) 275-278.
10.1126/science.1233000
Novoselova TV, Jackson D, Campbell DC, Clark AJL and
Chan LF (2013).
Melanocortin receptor accessory proteins in adrenal gland physiology and beyond. J Endocrinol vol. 217, (1) R1-11.
10.1530/JOE-12-0501
Prasad R, Hughes C,
Chan L, Peters C, Nathwani N, Clark A, Storr H and
Metherell L (2013).
A mutation in thioredoxin reductase 2 (TXNRD2) is associated with a predominantly adrenal phenotype in humans. Bioscientifica Endocrine Abstracts 1-1.
10.1530/endoabs.31.oc2.5
Ramachandrappa S, Gorrigan RJ, Clark AJL and
Chan LF (2013).
The melanocortin receptors and their accessory proteins. Front Endocrinol (Lausanne) vol. 4,
10.3389/fendo.2013.00009
Asai M, Ramachandrappa S, Joachim M, Shen Y, Zhang R, Nuthalapati N, Ramanathan V, Strochlic DE, Ferket P, Linhart K, Ho C, Novoselova TV, Garg S, Ridderstråle M, Marcus C, Hirschhorn JN, Keogh JM, O'Rahilly S,
Chan LF, Clark AJ, Farooqi IS and Majzoub JA (2013).
Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity. Science vol. 341, (6143) 275-278.
10.1126/science.12330002011

Jain V,
Metherell LA, David A, Sharma R, Sharma PK, Clark AJL and
Chan LF (2011).
Neonatal presentation of familial glucocorticoid deficiency resulting from a novel splice mutation in the melanocortin 2 receptor accessory protein. Eur J Endocrinol vol. 165, (6) 987-991.
10.1530/EJE-11-0581
Gorrigan RJ, Guasti L, King P, Clark AJ and
Chan LF (2011).
Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland. J Mol Endocrinol vol. 46, (3) 227-232.
10.1530/JME-11-0011
Chan LF, Vaidya M, Westphal B, Allgrove J, Martin L, Afshar F, Hindmarsh PC, Savage MO, Grossman AB and Storr HL (2011).
Use of intravenous etomidate to control acute psychosis induced by the hypercortisolaemia in severe paediatric Cushing's disease. Horm Res Paediatr vol. 75, (6) 441-446.
10.1159/0003244192010
Chan L, Albertsson-Wikland K, Camacho-Hübner C and Hochberg Z (2010).
Signal transduction in child health: closing the gap between clinical and basic research. Sci Signal vol. 3, (143)
10.1126/scisignal.3143mr3
Dias RP, Kumaran A,
Chan LF, Martin L, Afshar F, Matson M, Plowman PN, Monson JP, Besser GM, Grossman AB, Savage MO and Storr HL (2010).
Diagnosis, management and therapeutic outcome in prepubertal Cushing's disease. Eur J Endocrinol vol. 162, (3) 603-609.
10.1530/EJE-09-0509
Dias RP,
Chan LF,
Metherell LA, Pearce SHS and Clark AJL (2010).
Isolated Addison's disease is unlikely to be caused by mutations in MC2R, MRAP or STAR, three genes responsible for familial glucocorticoid deficiency. Eur J Endocrinol vol. 162, (2) 357-359.
10.1530/EJE-09-0720
Savage MO, Dias RP,
Chan LF, Afshar F, Plowman PN, Matson M, Grossman AB and STORR HL (2010).
Diagnosis and Treatment of Cushing’s Disease in Children. Pediatric Neuroendocrinology , Editors: Loche S, Cappa M, Ghizzoni L, Maghnie M and Savage MO.
Karger Publishers 10.1159/000262535
Savage MO, Dias RP,
Chan LF, Afshar F, Plowman NP, Matson M, Grossman AB and Storr HL (2010).
Diagnosis and treatment of Cushing's disease in children. Endocr Dev vol. 17, 134-145.
10.1159/0002625352009
Chan LF,
Metherell LA, Krude H, Ball C, O'Riordan SMP, Costigan C, Lynch SA, Savage MO, Cavarzere P and Clark AJL (2009).
Homozygous nonsense and frameshift mutations of the ACTH receptor in children with familial glucocorticoid deficiency (FGD) are not associated with long-term mineralocorticoid deficiency. Clin Endocrinol (Oxf) vol. 71, (2) 171-175.
10.1111/j.1365-2265.2008.03511.x
Chan LF, Webb TR, Chung T-T, Meimaridou E, Cooray SN, Guasti L,
Chapple JP, Egertová M, Elphick MR, Cheetham ME,
Metherell LA and Clark AJL (2009).
MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family. Proc Natl Acad Sci U S A vol. 106, (15) 6146-6151.
10.1073/pnas.0809918106
Chan LF, Chung T-T, Massoud AF,
Metherell LA and Clark AJL (2009).
Functional consequence of a novel Y129C mutation in a patient with two contradictory melanocortin-2-receptor mutations. Eur J Endocrinol vol. 160, (4) 705-710.
10.1530/EJE-08-0636
Cooray SN,
Chan L, Webb TR,
Metherell L and Clark AJL (2009).
Accessory proteins are vital for the functional expression of certain G protein-coupled receptors. Mol Cell Endocrinol vol. 300, (1-2) 17-24.
10.1016/j.mce.2008.10.004
Webb TR,
Chan L, Cooray SN, Cheetham ME,
Chapple JP and Clark AJL (2009).
Distinct melanocortin 2 receptor accessory protein domains are required for melanocortin 2 receptor interaction and promotion of receptor trafficking. Endocrinology vol. 150, (2) 720-726.
10.1210/en.2008-0941
Metherell LA, Chung TT,
Chan LF and Clark AJL (2009).
Genotype:phenotype relationships in familial glucocorticoid deficiency types 1 and 2. Horm Res vol. 72, 211-211.
Chan LF, David A, Jain V, Clark AJL and
Metherell LA (2009).
A novel splice mutation (IVSds3+3insTA) in the melanocortin 2 receptor accessory protein that leads to skipping of exon 3. Horm Res vol. 72, 70-70.

Dias RP, Kumaran A,
Chan LF, Martin L, Afshar F, Matson M, Plowman PN, Monson JP, Besser GM, Grossman AB, Savage MO and Storr HL (2009).
Prepubertal Cushing's disease: diagnosis, management and therapeutic outcome. Hormone Research vol. 72, 72-72.
Chan LF, Metherell LA, Krude H, Ball C, O'Riordan SM, Costigan C, Lynch SA, Savage MO, Cavarzere P and Clark AJ (2009).
Homozygous nonsense and frameshift mutations of the ACTH receptor in children with familial glucocorticoid deficiency (FGD) are not associated with long-term mineralocorticoid deficiency. Clin Endocrinol (Oxf) vol. 71, (2) 171-175.
10.1111/j.1365-2265.2008.03511.x2008

Chung TT, Webb TR,
Chan LF, Cooray SN,
Metherell LA, King PJ,
Chapple JP and Clark AJL (2008).
The majority of adrenocorticotropin receptor (melanocortin 2 receptor) mutations found in familial glucocorticoid deficiency type 1 lead to defective trafficking of the receptor to the cell surface. J Clin Endocrinol Metab vol. 93, (12) 4948-4954.
10.1210/jc.2008-1744
Savage MO,
Chan LF, Grossman AB and Storr HL (2008).
Work-up and management of paediatric Cushing's syndrome. Curr Opin Endocrinol Diabetes Obes vol. 15, (4) 346-351.
10.1097/MED.0b013e328305082f
O'Riordan SMP, Lynch SA, Hindmarsh PC,
Chan LF, Clark AJL and Costigan C (2008).
A novel variant of familial glucocorticoid deficiency prevalent among the Irish traveler population. J Clin Endocr Metab vol. 93, (7) 2896-2899.
10.1210/jc.2008-0034
O'Riordan SMP, Lynch SA, Hindmarsh PC,
Chan LF, Clark AJL and Costigan C (2008).
A novel variant of familial glucorticoid deficiency prevalent among the Irish traveler population. J Clin Endocrinol Metab. vol. 93, (7) 2896-2899.
10.1210/jc.2008-0034
Chan LF, Clark AJL and
Metherell LA (2008).
Familial glucocorticoid deficiency: advances in the molecular understanding of ACTH action. Horm Res vol. 69, (2) 75-82.
10.1159/000111810
Storr H, Alexandraki K,
Chan L, Martin L, Monson J, Besser M, Grossman A and Savage M (2008).
Comparisons in the epidemiology and diagnostic features between paediatric and adult Cushing's disease. Horm Res vol. 70, 24-25.
Chan L, Chung TT, Massoud A,
Metherell L and Clark A (2008).
Functional consequence of two opposing MC2R mutations in a child with severe FGD phenotype. Horm Res vol. 70, 23-23.

Savage MO,
Chan LF, Afshar F, Plowman PN, Grossman AB and Storr HL (2008).
Advances in the management of paediatric Cushing's disease. Horm Res vol. 69, (6) 327-333.
10.1159/0001173882007
Chan LF, Storr HL, Grossman AB and Savage MO (2007).
Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment. Arq Bras Endocrinol Metabol vol. 51, (8) 1261-1271.
10.1590/s0004-27302007000800012
Storr HL,
Chan LF, Grossman AB and Savage MO (2007).
Paediatric Cushing's syndrome: epidemiology, investigation and therapeutic advances. Trends Endocrin Met vol. 18, (4) 167-174.
10.1016/j.tem.2007.03.006
Chan LF, Storr HL, Plowman PN, Perry LA, Besser GM, Grossman AB and Savage MO (2007).
Long-term anterior pituitary function in patients with paediatric Cushing's disease treated with pituitary radiotherapy. Eur J Endocrinol vol. 156, (4) 477-482.
10.1530/EJE-06-0588
Savage MO, Storr HL,
Chan LF and Grossman AB (2007).
Diagnosis and treatment of pediatric Cushing's disease. Pituitary vol. 10, (4) 365-371.
10.1007/s11102-007-0056-42006
Chan L, Storr H, Plowman PN, Perry L, Monson J, Besser GM, Grossman A and Savage M (2006).
Anterior pituitary function in the long-term follow-up of five paediatric Cushing's disease patients treated with pituitary radiotherapy. Horm Res vol. 65, 186-186.
2004
Chan LF, Storr HL, Scheimberg I, Perry LA, Banerjee K, Miraki-Moud F, Camacho-Hubner C and Savage MO (2004).
Pseudo-precocious puberty caused by a juvenile granulosa cell tumor secreting androstenedione, inhibin and insulin-like growth factor-I. J Pediatr Endocr Met vol. 17, (4) 679-684.
10.1515/jpem.2004.17.4.679