Prof Kairbaan Hodivala-Dilke

Kairbaan Hodivala-Dilke

Professor

Barts Cancer Institute
Queen Mary University of London

Research

Cancer Models

Interests

Modelling the TME for human relevant therapy tests

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2025

Endothelial Cell pY397-FAK Expression Predicts the Risk of Breast Cancer Recurrences after Radiotherapy in the SweBCG91-RT Cohort
Drake RJG, Landén AH, Holmberg E, Tullberg AS, Killander F, Niméus E, Jordan A, McGuinness J et al.
Clinical Cancer Research, American Association For Cancer Research (Aacr) vol. 31 (7), 1323-1332.  
05-02-2025
Importance of integrin transmembrane helical interactions for antagonistic versus agonistic ligand behavior: Consequences for medical applications
Reuning U, D'Amore VM, Hodivala-Dilke K, Marinelli L, Kessler H
Bioorganic Chemistry, Elsevier vol. 156 
19-01-2025

2024

Targeting the tumour vasculature: from vessel destruction to promotion
Guelfi S, Hodivala-Dilke K, Bergers G
Nature Reviews Cancer, Springer Nature vol. 24 (10), 655-675.  
29-08-2024
Treatment with αvβ3-integrin-specific 29P attenuates pressure-overload induced cardiac remodelling after transverse aortic constriction in mice
Njegić A, Laid L, Zi M, Maniati E, Wang J, Chelu A, Wisniewski L, Hunter J et al.
Journal of Molecular and Cellular Cardiology Plus, Elsevier vol. 8 
12-03-2024

2023

Effects of senescence on the tumour microenvironment and response to therapy
Reynolds LE, Maallin S, Haston S, Martinez‐Barbera JP, Hodivala‐Dilke KM, Pedrosa A
The Febs Journal, Wiley vol. 291 (11), 2306-2319.  
01-11-2023
Author Correction: Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gómez-Escudero J, Muñoz-Félix JM, Batista S, Dukinfield M et al.
Nature Communications, Springer Nature vol. 14 (1) 
06-09-2023

2022

Primary tumor–derived systemic nANGPTL4 inhibits metastasis
Hübers C, Pari AAA, Grieshober D, Petkov M, Schmidt A, Messmer T, Heyer CM, Schölch S et al.
Journal of Experimental Medicine, Rockefeller University Press vol. 220 (1) 
21-10-2022
ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning
D'Amico G, Fernandez I, Gómez-Escudero J, Kim H, Maniati E, Azman MS, Mardakheh FK, Serrels B et al.
Development, The Company of Biologists vol. 149 (13) 
01-07-2022
Suppression of endothelial cell FAK expression reduces pancreatic ductal adenocarcinoma metastasis after gemcitabine treatmentEC FAK regulates gemcitabine treated liver metastasis

Cancer Research, American Association For Cancer Research (Aacr) vol. 82 (10), 1909-1925.  
29-03-2022
Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A et al.
Cell Reports, Elsevier vol. 38 (4) 
01-01-2022

2021

Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth

The Journal of Pathology, Wiley vol. 256 (2), 235-247.  
20-12-2021
Improved Immunotherapy Efficacy by Vascular Modulation
Newport EL, Pedrosa AR, Njegic A, Hodivala-Dilke KM, Muñoz-Félix JM
Cancers, Mdpi vol. 13 (20) 
17-10-2021
Correction to: Phosphorylation of pericyte FAK‑Y861 affects tumour cell apoptosis and tumour blood vessel regression
Lees DM, Reynolds LE, Pedrosa AR, Roy-Luzarraga M, Hodivala-Dilke KM
Angiogenesis, Springer Nature vol. 24 (3), 483-487.  
04-07-2021
Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression
Lees DM, Reynolds LE, Pedrosa AR, Roy-Luzarraga M, Hodivala-Dilke KM
Angiogenesis, Springer Nature vol. 24 (3), 471-482.  
17-03-2021
Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice
Delvecchio FR, Fincham REA, Spear S, Clear A, Roy-Luzarraga M, Balkwill FR, Gribben JG, Bombardieri M et al.
Cellular and Molecular Gastroenterology and Hepatology, Elsevier vol. 12 (5), 1543-1565.  
01-01-2021

2020

Regulation of tumour progression and metastasis by Endothelial-FAK upon chemotherapy treatment
Roy-Luzarraga M, Reynolds L, Hodivala-Dilke K
Pancreatology, Elsevier vol. 20 (8) 
01-12-2020
Association of Low Tumor Endothelial Cell pY397–Focal Adhesion Kinase Expression With Survival in Patients With Neoadjuvant-Treated Locally Advanced Breast Cancer
Roy-Luzarraga M, Abdel-Fatah T, Reynolds LE, Clear A, Taylor JG, Gribben JG, Chan S, Jones L et al.
Jama Network Open, American Medical Association (Ama) vol. 3 (10) 
01-10-2020
Tumor Cell–Derived Angiopoietin-2 Promotes Metastasis in Melanoma
Abdul Pari AA, Singhal M, Hübers C, Mogler C, Schieb B, Gampp A, Gengenbacher N, Reynolds LE et al.
Cancer Research, American Association For Cancer Research (Aacr) vol. 80 (12), 2586-2598.  
15-06-2020
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gómez-Escudero J, Muñoz-Félix JM, Batista S, Dukinfield M et al.
Nature Communications, Springer Nature vol. 11 (1) 
04-06-2020
Abstract A31: Tumor stroma in the development of acquired cancer therapy resistance
Gomez-Escudero J, Maniati E, Whiting F, Wang J, Graham T, Hodivala-Dilke K
 
01-06-2020
Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells
Wong P-P, Muñoz-Félix JM, Hijazi M, Kim H, Robinson SD, De Luxán-Delgado B, Rodríguez-Hernández I, Maiques O et al.
Cell, Elsevier vol. 181 (6), 1346-1363.e21.  
29-05-2020
Cancer associated fibroblast FAK regulates malignant cell metabolism
Demircioglu F, Wang J, Candido J, Costa ASH, Casado P, de Luxan Delgado B, Reynolds LE, Gomez-Escudero J et al.
Nature Communications, Springer Science and Business Media Llc vol. 11 (1) 
10-03-2020
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway
Wilcz‐Villega E, Carter E, Ironside A, Xu R, Mataloni I, Holdsworth J, Jones W, Moreno Béjar R et al.
Embo Molecular Medicine, Springer Nature vol. 12 (2) 
13-01-2020

2019

“Splitting the matrix”: intussusceptive angiogenesis meets MT1‐MMP
D'Amico G, Muñoz‐Félix JM, Pedrosa AR, Hodivala‐Dilke KM
Embo Molecular Medicine, Springer Nature vol. 12 (2) 
20-12-2019
Repurposing an anti‐cancer agent for the treatment of hypertrophic heart disease
Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J et al.
The Journal of Pathology, Wiley vol. 249 (4), 523-535.  
30-10-2019
Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861
Pedrosa A-R, Bodrug N, Gomez-Escudero J, Carter EP, Reynolds LE, Georgiou PN, Fernandez I, Lees DM et al.
Cancer Research, American Association For Cancer Research (Aacr) vol. 79 (17), 4371-4386.  
01-09-2019
Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations
Li J, Fukase Y, Shang Y, Zou W, Muñoz-Félix JM, Buitrago L, van Agthoven J, Zhang Y et al.
Acs Pharmacology & Translational Science, American Chemical Society (Acs) vol. 2 (6), 387-401.  
02-08-2019
Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction
Li Z, Solomonidis EG, Meloni M, Taylor RS, Duffin R, Dobie R, Magalhaes MS, Henderson BEP et al.
European Heart Journal, Oxford University Press (Oup) vol. 40 (30), 2507-2520.  
04-06-2019
C-type natriuretic peptide co-ordinates cardiac structure and function
Moyes AJ, Chu SM, Aubdool AA, Dukinfield MS, Margulies KB, Bedi KC, Hodivala-Dilke K, Baliga RS et al.
European Heart Journal, Oxford University Press (Oup) vol. 41 (9), 1006-1020.  
21-03-2019

2018

A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia.
Foxler DE, Bridge KS, Foster JG, Grevitt P, Curry S, Shah KM, Davidson KM, Nagano A et al.
Embo Mol Med 
21-06-2018

2017

Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3
Weinmüller M, Rechenmacher F, Marelli UK, Reichart F, Kapp TG, Räder AFB, Di Leva FS, Marinelli L et al.
Angewandte Chemie International Edition, Wiley vol. 56 (51), 16405-16409.  
23-11-2017
Focal Adhesion Kinase (FAK) tyrosine 397E mutation restores the vascular leakage defect in endothelium‐specific FAK‐kinase dead mice
Alexopoulou AN, Lees DM, Bodrug N, Lechertier T, Fernandez I, D'Amico G, Dukinfield M, Batista S et al.
The Journal of Pathology, Wiley vol. 242 (3), 358-370.  
01-06-2017
Multiple roles of integrin-α3 at the neuromuscular junction
Ross JA, Webster RG, Lechertier T, Reynolds LE, Turmaine M, Bencze M, Jamshidi Y, Cetin H et al.
Journal of Cell Science, The Company of Biologists vol. 130 (10), 1772-1784.  
06-04-2017
Dual role of pericyte α6β1-integrin in tumour blood vessels
Reynolds LE, D'Amico G, Lechertier T, Papachristodoulou A, Muñoz-Félix JM, De Arcangelis A, Baker M, Serrels B et al.
Journal of Cell Science, The Company of Biologists vol. 130 (9), 1583-1595.  
13-03-2017
Correction: A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma

Clinical Cancer Research, American Association For Cancer Research (Aacr) vol. 23 (3), 870-870.  
31-01-2017
Development of non-invasive imaging of integrin alpha-v-beta-6 (αvβ6)-positive lung cancers in advance of testing αvβ6-targeted therapies
Rudran B, Desai A, Luzarraga M, Hodivala-Dilke K, Foster J, Sosabowski J, Marshall J
 
01-01-2017

2016

Exploring Novel Methods for Modulating Tumor Blood Vessels in Cancer Treatment
Wong P-P, Bodrug N, Hodivala-Dilke KM
Current Biology, Elsevier vol. 26 (21), r1161-r1166.  
01-11-2016
αvβ3 Integrin and tumour blood vessels—learning from the past to shape the future
Demircioglu F, Hodivala-Dilke K
Current Opinion in Cell Biology, Elsevier vol. 42, 121-127.  
27-07-2016
Molecular Pathways: Endothelial Cell FAK--A Target for Cancer Treatment
Roy-Luzarraga M, Hodivala-Dilke K
Clinical Cancer Research, American Association For Cancer Research vol. 22 (15), 3718-3724.  
04-06-2016
Pancreatic stellate cells regulate blood vessel density in the stroma of pancreatic ductal adenocarcinoma
Di Maggio F, Arumugam P, Delvecchio FR, Batista S, Lechertier T, Hodivala-Dilke K, Kocher HM
Pancreatology, Elsevier 
01-06-2016
A promyelocytic leukemia protein-thrombospondin 2 axis and the risk of relapse in neuroblastoma.
Dvorkina M, Nieddu V, Chakelam S, Pezzolo A, Cantilena S, Leite AP, Chayka O, Regad T et al.
Clinical Cancer Research, American Association For Cancer Research 
13-04-2016

2015

Suppression of TGFβ and Angiogenesis by Type VII Collagen in Cutaneous SCC.
Martins VL, Caley MP, Moore K, Szentpetery Z, Marsh ST, Murrell DF, Kim MH, Avari M et al.
J Natl Cancer Inst vol. 108 (1) 
16-10-2015
G.O.9 Integrins are required for synaptic transmission and development of the neuromuscular junction
Ross J, Webster R, Lechertier T, Reynolds L, Muntoni F, Beeson D, Hodivala-Dilke K, Conti F
 
01-10-2015
Interleukin-6 Stimulates Defective Angiogenesis
Gopinathan G, Milagre C, Pearce OMT, Reynolds LE, Hodivala-Dilke K, Leinster DA, Zhong H, Hollingsworth RE et al.
Cancer Research, American Association For Cancer Research (Aacr) vol. 75 (15), 3098-3107.  
01-08-2015
Abstract 4162: Interleukin–6 stimulates defective angiogenesis
Gopinathan G, Milagre C, Pearce OMT, Reynolds L, Hodivala-Dilke K, Leinster A, Zhong H, Hollingsworth RE et al.
Cancer Research, American Association For Cancer Research (Aacr) vol. 75 (15_Supplement), 4162-4162.  
01-08-2015
Dual-Action Combination Therapy Enhances Angiogenesis while Reducing Tumor Growth and Spread

Cancer Cell, Elsevier vol. 27 (1), 123-137.  
01-01-2015
The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling
Birdsey GM, Shah AV, Dufton N, Reynolds LE, Almagro LO, Yang Y, Aspalter IM, Khan ST et al.
Developmental Cell, Elsevier vol. 32 (1), 82-96.  
01-01-2015
NOVEL DUAL-ACTION COMBINATION THERAPY ENHANCES ANGIOGENESIS WHILST REDUCING TUMOR GROWTH AND SPREAD

 
01-01-2015
REGULATION OF VASCULAR DEVELOPMENT AND ANGIOGENESIS BY THE TRANSCRIPTION FACTOR ERG
Birdsey GM, Shah AV, Dufton N, Reynolds LE, Almagro LO, Yang Y, Aspalter IM, Mason JC et al.
 
01-01-2015

2014

Generation of point-mutant FAK knockin mice.
Tavora B, Batista S, Alexopoulou AN, Kostourou V, Fernandez I, Robinson SD, Lees DM, Serrels B et al.
Genesis vol. 52 (11), 907-915.  
01-11-2014
106 Beta-3 integrin inhibition reduces inflammatory cytokine release but not anti-cancer activity of oncolytic adenovirus in ovarian cancer
Browne AK, Tookman LA, Ingemarsdotter CK, Bouwman R, Pirlo K, Wang Y, Hodivala-Dilke KM, McNeish IA et al.
 
01-11-2014
Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy.
Tavora B, Reynolds LE, Batista S, Demircioglu F, Fernandez I, Lechertier T, Lees DM, Wong P-P et al.
Nature vol. 514 (7520), 112-116.  
02-10-2014
Haematopoietic focal adhesion kinase deficiency alters haematopoietic homeostasis to drive tumour metastasis.
Batista S, Maniati E, Reynolds LE, Tavora B, Lees DM, Fernandez I, Elia G, Casanovas O et al.
Nat Commun vol. 5 
01-10-2014
203 Hypoxia-inducible Factor-1 Regulates Matrix Metalloproteinase-14 Expression: Underlying Effects of Hypoxia and Statins.
Moore AD, Hodgkinson C, Lapenna A, Zhang F, Witkowska K, Liang Ng F, Headland SE, Reynolds L et al.
 
01-06-2014
Tumour-associated endothelial-FAK correlated with molecular sub-type and prognostic factors in invasive breast cancer.
Alexopoulou AN, Ho-Yen CM, Papalazarou V, Elia G, Jones JL, Hodivala-Dilke K
Bmc Cancer vol. 14 
02-04-2014
Acute depletion of endothelial β3-integrin transiently inhibits tumor growth and angiogenesis in mice.
Steri V, Ellison TS, Gontarczyk AM, Weilbaecher K, Schneider JG, Edwards D, Fruttiger M, Hodivala-Dilke KM et al.
Circulation Research, American Heart Association vol. 114 (1), 79-91.  
03-01-2014
The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling
Shah AV, Birdsey GM, Reynolds LE, Dufton N, Almagro LO, Yang Y, Aspalter IM, Khan ST et al.
Angiogenesis vol. 17 (3), 715-715.  
01-01-2014

2013

Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen-1 and nidogen-2.
Martino-Echarri E, Fernández-Rodríguez R, Rodríguez-Baena FJ, Barrientos-Durán A, Torres-Collado AX, Plaza-Calonge MDC, Amador-Cubero S, Cortés J et al.
Int J Cancer vol. 133 (10), 2315-2324.  
15-11-2013
Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice.
Jones DT, Lechertier T, Reynolds LE, Mitter R, Robinson SD, Kirn-Safran CB, Hodivala-Dilke KM
Dis Model Mech vol. 6 (1), 115-124.  
01-01-2013
Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth.
Baker M, Reynolds LE, Robinson SD, Lees DM, Parsons M, Elia G, Hodivala-Dilke K
Plos One vol. 8 (5) 
01-01-2013
Dose- and schedule-dependent changes in vascular morphology after PI3K and PI3K/mTOR inhibition: in vitro vs. in vivo effects
Fokas E, Lechterier T, Hackl W, S-M M, McKenna WG, Hodivala-Dilke K, Muschel RJ
 
01-01-2013
FAK-heterozygous mice display enhanced tumour angiogenesis.
Kostourou V, Lechertier T, Reynolds LE, Lees DM, Baker M, Jones DT, Tavora B, Ramjaun AR et al.
Nat Commun vol. 4 
01-01-2013
Fascin 1 is dispensable for developmental and tumour angiogenesis.
Ma Y, Reynolds LE, Li A, Stevenson RP, Hodivala-Dilke KM, Yamashiro S, Machesky LM
Biol Open vol. 2 (11), 1187-1191.  
01-01-2013

2012

Focal adhesion kinase and tumour angiogenesis.
Lechertier T, Hodivala-Dilke K
J Pathol vol. 226 (2), 404-412.  
01-01-2012
Roles of α3-integrin in development of the neuromuscular system
Ross J, Lechertier T, Morgan J, Muntoni F, Hodivala-Dilke K, Conti F
 
01-01-2012
Gene expression analysis in human breast cancer associated blood vessels.
Jones DT, Lechertier T, Mitter R, Herbert JMJ, Bicknell R, Jones JL, Li J-L, Buffa F et al.
Plos One vol. 7 (10) 
01-01-2012
Up-regulation of αvβ6 integrin and fibronectin EDA in myoepithelial cells contribute to the angiogenic switch in pre-invasive breast cancer
Dreger SA, Payne SJ, Dawoud M, Robinson SD, Marshall JF, Hodivala-Dilke KM, Allen MD, Jones JL
 
01-01-2012

2011

Use of the mouse aortic ring assay to study angiogenesis.
Baker M, Robinson SD, Lechertier T, Barber PR, Tavora B, D'Amico G, Jones DT, Vojnovic B et al.
Nat Protoc vol. 7 (1), 89-104.  
22-12-2011
The role of β3-integrins in tumor angiogenesis: context is everything.
Robinson SD, Hodivala-Dilke KM
Curr Opin Cell Biol vol. 23 (5), 630-637.  
01-10-2011
Abstract SY16-03: Dose matters and angiogenesis
Hodivala-Dilke KM
Cancer Research, American Association For Cancer Research (Aacr) vol. 71 (8_Supplement) 
15-04-2011
Abstract 3479: Claudin-14: A novel regulator of angiogenesis
Baker M, Robinson SD, Hodivala-Dilke K, Ben-Yosef T
Cancer Research, American Association For Cancer Research (Aacr) vol. 71 (8_Supplement), 3479-3479.  
15-04-2011
Abstract 517: Deficiency of FAK in the bone marrow compartment enhances tumour metastasis
Batista SA, Reynolds L, Tavora B, Hodivala-Dilke K
Cancer Research, American Association For Cancer Research (Aacr) vol. 71 (8_Supplement), 517-517.  
15-04-2011
Dose matters and angiogenesis
Hodivala-Dilke KM
Cancer Research vol. 71 
15-04-2011
Abstract 3472: Endothelial FAK is required for tumor angiogenesis
Tavora B, Hodivala-dilke K
 
15-04-2011
Abstract 4848: Genetic profile of invasive breast cancer vasculature using laser capture microdissection (LCM) to capture vessels
Jones DT, Lechertier T, Herbert J, Bicknell R, Jones LJ, Harris AL, Hodivala-Dilke K
 
15-04-2011
Measuring angiogenesis in mice.
Tavora B, Batista S, Hodivala-Dilke K
Methods Mol Biol vol. 769, 351-358.  
01-01-2011

2010

Endothelial FAK is required for tumour angiogenesis.
Tavora B, Batista S, Reynolds LE, Jadeja S, Robinson S, Kostourou V, Hart I, Fruttiger M et al.
Embo Mol Med vol. 2 (12), 516-528.  
01-12-2010
Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.
da Silva RG, Tavora B, Robinson SD, Reynolds LE, Szekeres C, Lamar J, Batista S, Kostourou V et al.
Am J Pathol vol. 177 (3), 1534-1548.  
01-09-2010
Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome (Corrigendum)
Reynolds LE, Watson AR, Baker M, Jones TA, D'Amico G, Robinson SD, Joffre C, Garrido-Urbani S et al.
Nature vol. 466 (7304) 
15-07-2010
Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.
Reynolds LE, Watson AR, Baker M, Jones TA, D'Amico G, Robinson SD, Joffre C, Garrido-Urbani S et al.
Nature vol. 465 (7299), 813-817.  
10-06-2010
Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration.
Worth DC, Hodivala-Dilke K, Robinson SD, King SJ, Morton PE, Gertler FB, Humphries MJ, Parsons M
J Cell Biol vol. 189 (2), 369-383.  
19-04-2010
Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent.
D'Amico G, Robinson SD, Germain M, Reynolds LE, Thomas GJ, Elia G, Saunders G, Fruttiger M et al.
Plos One vol. 5 (3) 
22-03-2010
Deficiency of bone marrow beta3-integrin enhances non-functional neovascularization.
Watson AR, Pitchford SC, Reynolds LE, Direkze N, Brittan M, Alison MR, Rankin S, Wright NA et al.
J Pathol vol. 220 (4), 435-445.  
01-03-2010
Genetic ablation of the alpha 6-integrin subunit in Tie1Cre mice enhances tumour angiogenesis.
Germain M, De Arcangelis A, Robinson SD, Baker M, Tavora B, D'Amico G, Silva R, Kostourou V et al.
J Pathol vol. 220 (3), 370-381.  
01-02-2010
Regulation of lymphatic-blood vessel separation by endothelial Rac1 (vol 136, pg 4043, 2009)
D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V et al.
Development vol. 137 (2), 359-359.  
15-01-2010

2009

Microenvironmental Changes in DCIS: Myoepithelial Cells Change from Tumour Suppressor to Tumour Promoter
Dawoud MM, Jones D, Hodivala-Dilke K, Dreger S, Chelala C, Asaad NY, Jones L
 
15-12-2009
Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis.
Robinson SD, Reynolds LE, Kostourou V, Reynolds AR, da Silva RG, Tavora B, Baker M, Marshall JF et al.
J Biol Chem vol. 284 (49), 33966-33981.  
04-12-2009
Regulation of lymphatic-blood vessel separation by endothelial Rac1.
D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V et al.
Development vol. 136 (23), 4043-4053.  
01-12-2009
Will integrin inhibitors have proangiogenic effects in the clinic? Reply
Reynolds AR, Hodivala-Dilke KM
Nat Med vol. 15 (7), 727-727.  
01-07-2009
Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.
Reynolds AR, Hart IR, Watson AR, Welti JC, Silva RG, Robinson SD, Da Violante G, Gourlaouen M et al.
Nat Med vol. 15 (4), 392-400.  
01-04-2009
BETA3-INTEGRIN DEFICIENCY IN BONE MARROW ENHANCES ANGIOGENESIS IN A MOUSE MODEL OF PANCREATIC CANCER
Watson AR, Schier S, Wright NA, Hodivala-Dilke KM
 
01-04-2009
The role of cell adhesion pathways in angiogenesis.
Ramjaun AR, Hodivala-Dilke K
Int J Biochem Cell Biol vol. 41 (3), 521-530.  
01-03-2009

2008

alpha v beta 3 integrin and angiogenesis: a moody integrin in a changing environment
Hodivala-Dilke K
Curr Opin Cell Biol vol. 20 (5), 514-519.  
01-10-2008
Integrins - The keys to unlocking angiogenesis
Silva R, D'Amico G, Hodivala-Dilke KM, Reynolds LE
Arterioscl Throm Vas vol. 28 (10), 1703-1713.  
01-10-2008
The role of beta 3-integrin on bone marrow-derived cells in inflammatory bowel diseases
Schier S, Watson A, Hodivala-Dilke K, Wright NA
Gastroenterology vol. 134 (4), A257-A257.  
01-04-2008
alpha3beta1 integrin-controlled Smad7 regulates reepithelialization during wound healing in mice.
Reynolds LE, Conti FJ, Silva R, Robinson SD, Iyer V, Rudling R, Cross B, Nye E et al.
J Clin Invest vol. 118 (3), 965-974.  
01-03-2008
Efficient, inducible Cre-recombinase activation in vascular endothelium
Claxton S, Kostourou V, Jadeja S, Chambon P, Hodivala-Dilke K, Fruttiger M
Genesis vol. 46 (2), 74-80.  
01-02-2008
Farnesyltransferase inhibitors target multiple endothelial cell functions in angiogenesis.
Scott AN, Hetheridge C, Reynolds AR, Nayak V, Hodivala-Dilke K, Mellor H
Angiogenesis vol. 11 (4), 337-346.  
01-01-2008

2007

Regulation of COX-2-mediated signaling by alpha 3 type IV noncollagenous domain in tumor angiogenesis
Boosani CS, Mannam AP, Cosgrove D, Silva R, Hodivala-Dilke KM, Keshamouni VG, Sudhakar A
Blood vol. 110 (4), 1168-1177.  
15-08-2007
Activation of PPARbeta/delta induces endothelial cell proliferation and angiogenesis.
Piqueras L, Reynolds AR, Hodivala-Dilke KM, Alfranca A, Redondo JM, Hatae T, Tanabe T, Warner TD et al.
Arterioscler Thromb Vasc Biol vol. 27 (1), 63-69.  
01-01-2007

2006

Requirements for apoptotic cell contact in regulation of macrophage responses
Lucas M, Stuart LM, Zhang A, Hodivala-Dilke K, Febbraio M, Silverstein R, Savill J, Lacy-Hulbert A
J Immunol vol. 177 (6), 4047-4054.  
15-09-2006
Bone marrow contributes to functionally active cells in tumour stroma
Direkze NC, Jeffery R, Hodivala-Dilke K, Burke F, Hunt FT, Poulsom R, Balkwill F, Wright NA et al.
 
01-09-2006
Evaluating the role of b3-integrins in angiogenesis
Hodivala-Dilke KM, Reynolds L, Reynolds A, Robinson S, Wyder L, Lively J, Taverna D, Hynes R et al.
 
06-03-2006
Bone marrow-derived stromal cells express lineage-related messenger RNA species.
Direkze NC, Jeffery R, Hodivala-Dilke K, Hunt T, Playford RJ, Elia G, Poulsom R, Wright NA et al.
Cancer Res vol. 66 (3), 1265-1269.  
01-02-2006
Novel roles for integrins in tumour angiogenesis
Germain M, Silva R, Reynolds L, Robinson S, DiPersio M, Kreidberg J, Georges-Labouesse E, Hodivala-Dilke K
 
01-01-2006
Generation of genetically modified embryonic stem cells for the development of knockout mouse animal model systems.
Robinson SD, Wilson S, Hodivala-Dilke KM
Methods Mol Med vol. 120, 465-477.  
01-01-2006
Primary mouse endothelial cell culture for assays of angiogenesis.
Reynolds LE, Hodivala-Dilke KM
Methods Mol Med vol. 120, 503-509.  
01-01-2006

2005

Therapeutic expression of the platelet-specific integrin, alpha IIb beta 3, in a murine model for Glanzmann thrombasthenia
Fang J, Hodivala-Dilke K, Johnson BD, Du LM, Hynes RO, White GC, Wilcox DA
Blood vol. 106 (8), 2671-2679.  
15-10-2005
Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth
Lamagna C, Hodivala-Dilke KM, Imhof BA, Aurrand-Lions M
Cancer Res vol. 65 (13), 5703-5710.  
01-07-2005
Bone marrow contributes functionally active cell types to tumour stroma
Direkze N, Jeffery R, Hodivala-Dilke K, Burke F, Hunt T, Poulsom R, Alison M, Balkwill F et al.
 
01-04-2005
Bone marrow contributes to functionally active cells in tumour stroma
Direkze NC, Jeffery R, Hodivala-Dilke K, Burke F, Hunt FT, Poulsom R, Alison MR, Balkwill F et al.
 
01-04-2005
Transplanted Bone marrow cells engraft within the mouse epidermis and proliferate with no evidence of cell fusion
Brittan M, Braun KM, Reynolds LM, Conti FJ, Reynolds AR, Poulsom R, Alison MR, Wright NA et al.
 
01-03-2005
Accelerated re-epithelialization in beta3-integrin-deficient- mice is associated with enhanced TGF-beta1 signaling.
Reynolds LE, Conti FJ, Lucas M, Grose R, Robinson S, Stone M, Saunders G, Dickson C et al.
Nat Med vol. 11 (2), 167-174.  
01-02-2005
Bone marrow cells engraft within the epidermis and proliferate in vivo with no evidence of cell fusion.
Brittan M, Braun KM, Reynolds LE, Conti FJ, Reynolds AR, Poulsom R, Alison MR, Wright NA et al.
J Pathol vol. 205 (1), 1-13.  
01-01-2005

2004

Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.
McLean GW, Komiyama NH, Serrels B, Asano H, Reynolds L, Conti F, Hodivala-Dilke K, Metzger D et al.
Genes Dev vol. 18 (24), 2998-3003.  
15-12-2004
Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts.
Direkze NC, Hodivala-Dilke K, Jeffery R, Hunt T, Poulsom R, Oukrif D, Alison MR, Wright NA
Cancer Res vol. 64 (23), 8492-8495.  
01-12-2004
Elevated Flk1 (vascular endothelial growth factor receptor 2) signaling mediates enhanced angiogenesis in beta3-integrin-deficient mice.
Reynolds AR, Reynolds LE, Nagel TE, Lively JC, Robinson SD, Hicklin DJ, Bodary SC, Hodivala-Dilke KM
Cancer Res vol. 64 (23), 8643-8650.  
01-12-2004
Beta3-integrin regulates vascular endothelial growth factor-A-dependent permeability.
Robinson SD, Reynolds LE, Wyder L, Hicklin DJ, Hodivala-Dilke KM
Arterioscler Thromb Vasc Biol vol. 24 (11), 2108-2114.  
01-11-2004
Bone marrow contributes to tumour stroma
Direkze NC, Hodivala-Dilke K, Jeffery R, Hunt T, Oukrif D, Preston SL, Alison MR, Wright NA
 
01-09-2004
Bone marrow contributes to tumour stroma
Direkze NC, Hodivala-Dilke K, Jeffery R, Hunt T, Preston SL, Alison MR, Wright NA
 
01-04-2004

2003

Integrins and angiogenesis: unlocking the route to gene therapy.
Mistry A, Harbottle R, Hart S, Hodivala-Dilke KM
Curr Opin Mol Ther vol. 5 (6), 603-610.  
01-12-2003
A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning.
Petiot A, Conti FJA, Grose R, Revest J-M, Hodivala-Dilke KM, Dickson C
Development vol. 130 (22), 5493-5501.  
01-11-2003
Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis.
Alugupalli KR, Michelson AD, Joris I, Schwan TG, Hodivala-Dilke K, Hynes RO, Leong JM
Blood vol. 102 (8), 2843-2850.  
15-10-2003
Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes.
Wan H, Stone MG, Simpson C, Reynolds LE, Marshall JF, Hart IR, Hodivala-Dilke KM, Eady RAJ
J Cell Sci vol. 116 (Pt 20), 4239-4248.  
15-10-2003
Integrins in angiogenesis: multitalented molecules in a balancing act.
Hodivala-Dilke KM, Reynolds AR, Reynolds LE
Cell Tissue Res vol. 314 (1), 131-144.  
01-10-2003
Bone marrow derived cells contribute to a population of fibroblasts and myofibroblasts which engraft to multiple sites, including the gastrointestinal tract
Direkze NC, Forbes SJ, Brittan M, Hunt T, Jeffery R, Preston SL, Poulsom R, Hodivala-Dilke K et al.
 
01-09-2003
alpha3beta1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis.
Conti FJA, Rudling RJ, Robson A, Hodivala-Dilke KM
J Cell Sci vol. 116 (Pt 13), 2737-2747.  
01-07-2003
Therapeutic expression of a platelet-specific integrin, alpha IIb beta 3
Wilcox DA, Hodivala-Dilke KM, Johnson BD, Hynes RO, White GC
 
01-05-2003
Bone marrow derived cells contribute to a population of fibroblasts and myofibroblasts which engraft to multiple sites, including the gastrointestinal tract
Direkze NC, Forbes S, Brittan M, Hunt T, Jeffrey R, Preston S, Poulsom R, Hodivala-Dilke K et al.
 
01-04-2003
Nanoparticle-mediated gene delivery to tumour neovasculature.
Reynolds AR, Moein Moghimi S, Hodivala-Dilke K
Trends Mol Med vol. 9 (1), 2-4.  
01-01-2003
Multiple organ engraftment by bone-marrow-derived myofibroblasts and fibroblasts in bone-marrow-transplanted mice.
Direkze NC, Forbes SJ, Brittan M, Hunt T, Jeffery R, Preston SL, Poulsom R, Hodivala-Dilke K et al.
Stem Cells vol. 21 (5), 514-520.  
01-01-2003

2002

Lung repair by haematopoietic stem cells (HSC) after bone marrow transplant (BMT)
Jones SM, Hunt T, Brittan M, Jeffery R, Forbes S, Hodivala-Dilke K, Alison M, Wright N et al.
 
01-12-2002
Lineage-specific correction of Glanzmann thrombasthenia by expression of a functional hybrid murine-human alpha IIb beta 3 integrin complex on the surface of platelets of beta 3-knockout mice.
Wilcox DA, Hodivala-Dilke KM, Johnson BD, Hynes RO, White GC
 
16-11-2002
Diversity of desmoplakin expression in basal palm keratinocytes: A possible clue to the identification of epidermal stem cells
Wan H, Marshall J, Reynolds LE, Stone MG, McGrath JA, Hodivala-Dilke KM, Eady RAJ
J Invest Dermatol vol. 119 (3), 714-714.  
01-09-2002
CD36 or alphavbeta3 and alphavbeta5 integrins are not essential for MHC class I cross-presentation of cell-associated antigen by CD8 alpha+ murine dendritic cells.
Schulz O, Pennington DJ, Hodivala-Dilke K, Febbraio M, Reis e Sousa C
J Immunol vol. 168 (12), 6057-6065.  
15-06-2002
Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies.
Francis SE, Goh KL, Hodivala-Dilke K, Bader BL, Stark M, Davidson D, Hynes RO
Arterioscler Thromb Vasc Biol vol. 22 (6), 927-933.  
01-06-2002
Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colon.
Brittan M, Hunt T, Jeffery R, Poulsom R, Forbes SJ, Hodivala-Dilke K, Goldman J, Alison MR et al.
Gut vol. 50 (6), 752-757.  
01-06-2002
Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colon
Forbes SJ, Hunt T, Brittan M, Jeffery R, Poulsom R, Hodivala-Dilke K, Alison MR, Wright NA
Gut vol. 50, A35-A35.  
01-04-2002
Bone marrow derivation of intestinal subepithelial myofibroblasts in the mouse and human small intestine and colon
Brittan M, Hunt T, Jeffery R, Poulsom R, Forbes S, Hodivala-Dilke K, Alison M, Wright NA
Gastroenterology vol. 122 (4), A95-A96.  
01-04-2002
Primary mouse keratinocyte culture.
Hodivala-Dilke K
Methods Mol Biol vol. 188, 139-144.  
01-01-2002
Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins.
Reynolds LE, Wyder L, Lively JC, Taverna D, Robinson SD, Huang X, Sheppard D, Hynes RO et al.
Nat Med vol. 8 (1), 27-34.  
01-01-2002
The diverse roles of integrins and their ligands in angiogenesis.
Hynes RO, Lively JC, McCarty JH, Taverna D, Francis SE, Hodivala-Dilke K, Xiao Q
Cold Spring Harb Symp Quant Biol vol. 67, 143-153.  
01-01-2002

2001

Sticky science is skin deep
Hodivala-Dilke K
Journal of Cell Science, The Company of Biologists vol. 114 (20), 3582-3582.  
15-10-2001
Kidney from bone marrow in humans and mice.
Forbes SJ, Wyles SM, Ryan ED, Navaratnarasah S, Hodivala-Dilke KM, Jeffrey R, Hunt T, Alison MR et al.
J Pathol vol. 195, 3A-3A.  
01-09-2001
Bone marrow contributes to renal parenchymal turnover and regeneration.
Poulsom R, Forbes SJ, Hodivala-Dilke K, Ryan E, Wyles S, Navaratnarasah S, Jeffery R, Hunt T et al.
J Pathol vol. 195 (2), 229-235.  
01-09-2001
Bone marrow stem cells make hepatocytes with replicative potential.
Forbes SJ, Alison MR, Hodivala-Dilke KM, Jeffery R, Poulsom R, Wright NA
Gastroenterology vol. 120 (5), A62-A62.  
01-04-2001
Hepatocytes derived from bone marrow stem cells demonstrate polyploidisation
Forbes SJ, Hodivala-Dilke KM, Jeffery R, Alison MR, Poulsom R, Thomas H, Wright NA
J Hepatol vol. 34, 20-21.  
01-04-2001
Hepatocytes derived from bone marrow stem cells show polyploidization in humans and mice
Forbes SJ, Hodivala-Dilke KM, Jeffery R, Hunt T, Alison MR, Poulsom R, Wright NA
Gut vol. 48, A65-A66.  
01-03-2001

2000

In vitro characterization of integrin-deficient endothelial cells and aortic explants
Lively JC, Hodivala-Dilke K, Hynes RO
Mol Biol Cell vol. 11, 51A-51A.  
01-12-2000
Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts
McHugh KP, Hodivala-Dilke K, Zheng M-H, Namba N, Lam J, Novack D, Feng X, Ross FP et al.
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 105 (4), 433-440.  
15-02-2000

1999

Integrins in vascular development
Hynes RO, Bader BL, Hodivala-Dilke K
Brazilian Journal of Medical and Biological Research, Fapunifesp (Scielo) vol. 32 (5), 501-510.  
01-05-1999
β3-integrin–deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival
Hodivala-Dilke KM, McHugh KP, Tsakiris DA, Rayburn H, Crowley D, Ullman-Culleré M, Ross FP, Coller BS et al.
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 103 (2), 229-238.  
15-01-1999
Insights and Questions Arising from Studies of a Mouse Model of Glanzmann Thrombasthenia
Hynes RO, Hodivala-Dilke KM
Thrombosis and Haemostasis, Thieme vol. 82 (02), 481-485.  
01-01-1999
Hemostasis in the Mouse (Mus musculus): A Review
Tsakiris DA, Scudder L, Hodivala-Dilke K, Hynes RO, Coller BS
Thrombosis and Haemostasis, Thieme vol. 81 (02), 177-188.  
01-01-1999

1998

Novel Roles for α3β1 Integrin as a Regulator of Cytoskeletal Assembly and as a Trans-dominant Inhibitor of Integrin Receptor Function in Mouse Keratinocytes
Hodivala-Dilke KM, DiPersio CM, Kreidberg JA, Hynes RO
Journal of Cell Biology, Rockefeller University Press vol. 142 (5), 1357-1369.  
07-09-1998

1997

alpha 3 beta 1 integrin is required for normal development of the epidermal basement membrane
DiPersio CM, HodivalaDilke KM, Jaenisch R, Kreidberg JA, Hynes RO
J Cell Biol vol. 137 (3), 729-742.  
05-05-1997

1995

Calcium-Induced Changes in Distribution and Solubility of Cadherins, Integrins and Their Associated Cytoplasmic Proteins in Human Keratinocytes
Braga VMM, Hodivala KJ, Watt FM
Cell Communication & Adhesion, Taylor & Francis vol. 3 (3), 201-215.  
01-01-1995

1994

Integrin expression and function in HPV 16-immortalised human keratinocytes in the presence or absence of v-Ha-ras. Comparison with cervical intraepithelial neoplasia.
Hodivala KJ, Pei XF, Liu QY, Jones PH, Rytina ER, Gilbert C, Singer A, Watt FM
Oncogene vol. 9 (3), 943-948.  
01-03-1994
Cell Adhesion: Fibronectin and integrin knockouts come unstuck
Watt FM, Hodivala KJ
Current Biology, Elsevier vol. 4 (3), 270-272.  
01-03-1994
Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation
Hodivala K, Watt F
Journal of Cell Biology, Rockefeller University Press vol. 124 (4), 589-600.  
15-02-1994

1991

Detection of mature malaria infections in live mosquitoes
Billingsley PF, Hodivala KJ, Winger LA, Sinden RE
Transactions of The Royal Society of Tropical Medicine and Hygiene, Oxford University Press (Oup) vol. 85 (4), 450-453.  
01-07-1991

1990

An antigen specific to the liver stage of rodent malaria recognized by a monoclonal antibody
SUHRBIER A, WINGER L, O'DOWD C, HODIVALA K, SINDEN RE
Parasite Immunology, Wiley vol. 12 (4‐5), 473-481.  
01-09-1990
The development and routine application of high-density exoerythrocytic-stage cultures of Plasmodium berghei.
Sinden RE, Suhrbier A, Davies CS, Fleck SL, Hodivala K, Nicholas JC
Bulletin of The World Health Organization vol. 68 Suppl (Suppl), 115-125.  
01-01-1990
A liver-stage specific antigen of P. berghei identified by a monoclonal antibody.
Winger L, Suhrbier A, O'Dowd CA, Hodivala KJ, Sinden RE
Bulletin of The World Health Organization vol. 68 Suppl (Suppl), 172-177.  
01-01-1990

1989

Contrasts in antigen expression in the erythrocytic and exoerythrocytic stages of rodent malaria
Suhrbier A, Wiser MF, Winger L, Harte P, Newton MF, Hodivala KJ, Nicholas J, Sinden RE
Parasitology, Cambridge University Press (Cup) vol. 99 (2), 165-170.  
01-10-1989

Grants

solid heart iconGrants of specific relevance to Predictive in vitro Models
bullet iconMapping ethnicity driven changes in breast cancer biology
Kairbaan Hodivala-Dilke
£60,898 Barts and the London Charity
01-05-2025 - 30-04-2026
bullet iconImaging tools for the early signposting of treatment resistance and metastasis
Kairbaan Hodivala-Dilke
£249,477 CR-UK Cancer Research UK
01-01-2025 - 30-06-2027
bullet iconMultiomic Analysis of Immunotherapy Features Evidencing Success & Toxicity
Kairbaan Hodivala-Dilke, Thomas Powles and Bernadett Szabados
£318,526 MRC Medical Research Council
01-08-2024 - 31-07-2028
bullet iconExploiting the effects of mural cell b3-integrin expression in the control of cancer growth, resistan
Kairbaan Hodivala-Dilke
£1,798,616 CR-UK Cancer Research UK
01-11-2021 - 31-10-2026
bullet iconNovel Combination Strategies for the Improved Treatment of Lung Cancer
Kairbaan Hodivala-Dilke
£445,614 Barts and the London Charity
19-04-2021 - 15-02-2026
bullet iconInvestigating the role of vascular endothelial-cell senescence driving resistance to DNA-damaging therapies and metastasis formation in lung cancer
Kairbaan Hodivala-Dilke
£536,663 MRC Medical Research Council
01-01-2021 - 23-09-2025
bullet iconManipulating the tumour endothelium and effects on enhancing radiotherapy
Kairbaan Hodivala-Dilke
£381,144 Cancer Research UK
01-10-2020 - 01-06-2026
bullet iconReducing pancreatic cancer metastasis by targetting the endothelial cell niche
Kairbaan Hodivala-Dilke
£200,000 PCRF Pancreatic Cancer Research Fund
01-04-2020 - 28-02-2026


bullet iconDevelopment of endothelial targeting antibody-PROTAC conjugate for improved sensitisation to DNA-dam -Resub
Kairbaan Hodivala-Dilke
£27,740 Barts and the London Charity
01-08-2023 - 01-09-2025
bullet iconInvestigating the effect of CDK7i on PDAC -Carrick Therapeutics
Kairbaan Hodivala-Dilke
£25,072 Carrick Therapeutics Limited
01-12-2022 - 30-11-2023
bullet iconTargeting radiation-induced vascular dysfunction and inflammation to modulate responses to therapy
Kairbaan Hodivala-Dilke
£43,768 CR-UK Cancer Research UK
01-09-2022 - 31-08-2023
bullet iconDevelopment of an improved human disease-relevant in vivo lung cancer model.
Tyson Sharp, Kairbaan Hodivala-Dilke, John Gribben and Michael Sheaff
£48,256 Barts and the London Charity
01-07-2022 - 31-08-2024
bullet iconEstablishing Radiation Research Infrastructure at QMUL
Kairbaan Hodivala-Dilke
£49,788 Barts and the London Charity
01-01-2022 - 31-12-2022
bullet iconTargeting the tumour microenvironment to enhance immunotherapy: A cross-disciplinary approach to ass
Kairbaan Hodivala-Dilke
£7,000 CR-UK Cancer Research UK
01-07-2021 - 30-06-2022
bullet iconUtilising novel, blood vessel-targeting aptamers to improve radiotherapy sensitivity a newly optimiz
Kairbaan Hodivala-Dilke
£19,763 CR-UK Cancer Research UK
01-07-2021 - 30-06-2022
bullet iconEnhancing radiotherapy sensitisation and improving cancer control by modulating tumour microenvironment derived angiocrine signalling
Kairbaan Hodivala-Dilke
£145,664 CR-UK Cancer Research UK
28-09-2020 - 27-09-2024
bullet iconImproving non-small cell lung cancer outcome by improving immunotherapy (extension)
Kairbaan Hodivala-Dilke
£26,000 Barts and the London Charity
01-10-2019 - 01-05-2021
bullet iconExploiting the tumour microenvironment to enhance therapy in cancer treatment - Bridging Fund
Kairbaan Hodivala-Dilke
£37,038 Barts and the London Charity
01-09-2019 - 28-02-2023
bullet iconImproving the efficacy of immunotherapy in advanced lung cancer
Kairbaan Hodivala-Dilke
£208,131 Worldwide Cancer Research
01-04-2019 - 21-09-2023
bullet iconThe role of T-Cells within tertiary lymphoid structures in pancreatic ductal adenocarcinoma
Hemant Kocher, John Gribben and Kairbaan Hodivala-Dilke
£197,313 PCRF Pancreatic Cancer Research Fund
01-02-2019 - 30-04-2023
bullet iconRepurposing Low Dose RGD-mimetics for Improved Heart Failure Treatment
Kairbaan Hodivala-Dilke and Adrian Hobbs
£232,729 BHF British Heart Foundation
01-01-2019 - 31-12-2021
bullet iconFaculty recruitment; Targeting the Tumour Stroma-Basic Biology to Therapeutic Innovation
Nicholas Lemoine, Victoria Marta Sanz-Moreno, Kamil Kranc and Kairbaan Hodivala-Dilke
£2,500,000 Barts and the London Charity
01-10-2018 - 31-01-2024
bullet iconImproving non-small cell lung cancer outcome by improving immunotherapy
Kairbaan Hodivala-Dilke
£48,880 Barts and the London Charity
01-09-2018 - 31-08-2019
bullet iconTail Vein Injection Novintum - 2
Kairbaan Hodivala-Dilke
£18,270 NOVINTUM BIOSCIENCE LTD
31-01-2018 - 28-02-2018
bullet iconUsing a Xenograft Mouse Model to Test Tumourigenicity / Metastases of IR Cells
Kairbaan Hodivala-Dilke
£39,380 NOVINTUM BIOSCIENCE LTD
20-08-2017 - 30-11-2017
bullet iconPhD Studentship - Dukinfield
Kairbaan Hodivala-Dilke
£36,000 BHF British Heart Foundation
01-08-2017 - 30-09-2018
bullet iconDual action therapy targeting tourmour stromal and malignant cell compartments for pancreatic ductal adenocarcinoma
Kairbaan Hodivala-Dilke
£249,167 Worldwide Cancer Research
15-02-2016 - 14-02-2019
bullet iconImproved treatment strategy for advanced NSC lung cancer
Kairbaan Hodivala-Dilke
£237,397 Barts and the London Charity
01-10-2015 - 30-09-2018
bullet iconTargeting tumour blood vessels to alter angiocrine factors and enhance chemosensitisation
Kairbaan Hodivala-Dilke
£148,986 CR-UK Cancer Research UK
01-10-2015 - 30-09-2019
bullet iconTargeting tumour blood vessels to alter angiocrine factors and enhance chemossensitisation
Kairbaan Hodivala-Dilke
£2,638,598 Cancer Research UK
01-10-2015 - 31-07-2022