Publications

Publications of specific relevance to Predictive in vitro Models
2019

de Gaetano M, Butler E, Gahan K, Zanetti A, Marai M,
Chen J, Cacace A, Hams E, Maingot C, McLoughlin A, Brennan E, Leroy X, Loscher CE, Fallon P,
Perretti M, Godson C and Guiry PJ (2019).
Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A4 mimetics (sLXms). European Journal of Medicinal Chemistry vol. 162, 80-108.
10.1016/j.ejmech.2018.10.0492018
Chen J, Hamers AJP, Finsterbusch M,
Massimo G, Zafar M, Corder R, Colas RA, Dalli J, Thiemermann C and Ahluwalia A (2018).
Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis. Faseb J fj201701303-fj201701303.
10.1096/fj.201701303R
Khan AI, Kapoor A,
Chen J, Martin L, Rogazzo M, Mercier T, Decosterd L, Collino M and Thiemermann C (2018).
The Antimalarial Drug Artesunate Attenuates Cardiac Injury in A Rodent Model of Myocardial Infarction. Shock vol. 49, (6) 675-681.
10.1097/SHK.00000000000009632017

Purvis GSD, Chiazza F,
Chen J, Loiola RA, Martin L, Fountoulakis N, Gnudi L, Collino M, Thiemermann C and
Solito E (2017).
Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes. Springer Verlag Diabetologia 10.1007/s00125-017-4469-y
Johnson FL, Patel NSA, Purvis GSD, Chiazza F,
Chen J, Sordi R, Hache G, Merezhko VV, Collino M, Yaqoob MM and Thiemermann C (2017).
Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis. J Am Heart Assoc vol. 6, (7)
10.1161/JAHA.116.005092
Martin L, Gombert A,
Chen J, Liebens J, Verleger J, Kalder J, Marx G, Jacobs M, Thiemermann C and Schuerholz T (2017).
The β-d-Endoglucuronidase Heparanase Is a Danger Molecule That Drives Systemic Inflammation and Correlates with Clinical Course after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair: Lessons Learnt from Mice and Men. Frontiers Media Front Immunol vol. 8, 681-681.
10.3389/fimmu.2017.006812016
Chen J and Thiemermann C (2016).
Selenium and niacin for sepsis therapy: The sum is greater than its parts. Critical Care Medicine vol. 44, (6) 1256-1257.
10.1097/CCM.0000000000001493
Chen J, Kieswich J, Chiazza F, Moyes A, Gobbetti T, Purvis G, Salvatori D, Patel N,
Perretti M,
Hobbs A, Collino M, Yaqoob M and THIEMERMANN C (2016).
IkB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD. American Society of Nephrology Journal of The American Society of Nephrology 10.1681/ASN.20150606702014

Gobbetti T, Coldewey SM, Chen J, McArthur S, Le Faouder P, Cenac N, Flower RJ, Thiemermann C and
Perretti M (2014).
Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis. Proceedings of The National Academy of Sciences of The United States of America vol. 111, (52) 18685-18690.
10.1073/pnas.1410938111
Chen J, Chiazza F, Collino M, Patel NSA, Coldewey SM and Thiemermann C (2014).
Gender dimorphism of the cardiac dysfunction in murine sepsis: Signalling mechanisms and age-dependency. Plos One vol. 9, (6)
10.1371/journal.pone.0100631