Publications

Publications of specific relevance to Predictive in vitro Models
2020

Sheikh MH, Henson S, Loiola RA, Mercurio S, Colamatteo A, Maniscalco GT, De Rosa V,
Mcarthur S and
Solito E (2020).
Immuno-metabolic impact of the multiple sclerosis patients’ sera on endothelial cells of the blood-brain barrier. Biomed Central Journal of Neuroinflammation 10.1186/s12974-020-01810-82019

Callender L, Carroll E, BOBER E, Akbar A,
Solito E and Henson S (2019).
Mitochondrial mass governs the extent of human T cell senescence. John Wiley & Sons Ltd Aging Cell vol. 19, (2)
10.1111/acel.13067
Solito E, Montague-Cardoso K, Pitcher T, Chisolm K, Salera G, Lindstrom E, Hewitt E and Malcangio M (2019).
Changes in vascular permeability in the spinal cord contribute to chemotherapy- induced neuropathic pain. Elsevier Brain Behaviour and Immunity 10.1016/j.bbi.2019.10.018
Solito E, Zub E, Canet G, Garbelli R, Blaquiere M, Rossini L, Pastori C, Sheikh M, Reutelingsperger C, Klement W, de Bock F, Audinat E, Givalois L and Marchi N (2019).
The GR-ANXA1 pathway is a pathological player and a candidate target in epilepsy., Editors: Weksler B.
Federation of American Society of Experimental Biology The Faseb Journal 10.1096/fj.201901596R
Solito E, Colamatteo A, Maggioli E, Azevedo Loiola R, Sheikh M, Cali G, Bruzzese D, Maniscalco T, Centonze D, Buttari F, Lanzillo R, Perna F, Zuccarelli B, Mottola M, Cassano S, Galgani M and De Rosa V (2019).
Reduced Annexin A1 expression associates with disease severity and inflammation in multiple sclerosis patients. American Association of Immunologists Journal of Immunology 10.4049/jimmunol.1801683
da Rocha GHO, Loiola RA, Pantaleão LDN, Reutelingsperger C,
Solito E and Farsky SHP (2019).
Control of expression and activity of peroxisome proliferated-activated receptor γ by Annexin A1 on microglia during efferocytosis. Wiley Cell Biochemistry and Function 10.1002/cbf.3433
Loiola RA, Wickstead ES,
Solito E and
Mcarthur S (2019).
Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Frontiers Media Frontiers in Endocrinology 10.3389/fendo.2019.00420
Purvis GSD, Collino M, Loiola RA, Baragetti A, Chiazza F, Brovelli M, Sheikh MH, Collotta D, Cento A, Mastrocola R, Aragno M, Cutrin JC, Reutelingsperger C, Grigore L, Catapano AL, Yaqoob MM, Norata GD,
Solito E and Thiemermann C (2019).
Identification of Annexina1 as an endogenous regulator of RhoA, and its role in the pathophysiology and experimental therapy of type-2 diabetes. Frontiers in Immunology vol. 10, (MAR)
10.3389/fimmu.2019.00571
Loiola RA, Wickstead ES,
Solito E and
McArthur S (2019).
Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Front Endocrinol (Lausanne) vol. 10,
10.3389/fendo.2019.004202018
SOLITO E and SHEIKH M (2018).
Annexin A1: Uncovering the Many Talents of an Old Protein. Mdpi Ag International Journal of Molecular Sciences vol. 19,
10.3390/ijms190410452017

Purvis GSD, Chiazza F,
Chen J, Loiola RA, Martin L, Fountoulakis N, Gnudi L, Collino M, Thiemermann C and
Solito E (2017).
Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes. Springer Verlag Diabetologia 10.1007/s00125-017-4469-y
Lima KM, Vago JP, Caux TR, Negreiros-Lima GL, Sugimoto MA, Tavares LP, Arribada RG, Carmo AAF, Galvão I, Costa BRC, Soriani FM, Pinho V,
Solito E,
Perretti M, Teixeira MM and Sousa LP (2017).
The resolution of acute inflammation induced by cyclic AMP is dependent on Annexin A1. Journal of Biological Chemistry vol. 292, (33) 13758-13773.
10.1074/jbc.M117.8003912016
McArthur S, Loiola RA, Maggioli E, Errede M, Virgintino D and
SOLITO E (2016).
The restorative role of annexin A1 at the blood–brain barrier. Biomed Central Fluids and Barriers of The Cns vol. 13, (17)
10.1186/s12987-016-0043-0
SOLITO E, Loiola R, Ries M, Shah U, Gentleamn S and Sastre M (2016).
The anti-inflammatory Annexin A1 induces
the clearance and degradation of the
amyloid-β peptide. Biomed Central Journal of Neuroinflammation vol. 13,
10.1186/s12974-016-0692-6
Sinniah A, Yazid S,
Perretti M,
Solito E and Flower RJ (2016).
The role of the Annexin-A1/FPR2 system in the regulation of mast cell degranulation provoked by compound 48/80 and in the inhibitory action of nedocromil. International Immunopharmacology vol. 32, 87-95.
10.1016/j.intimp.2016.01.003
Maggioli E, McArthur S, Mauro C, Kieswich J, Kusters DHM, Reutelingsperger CPM, Yaqoob M and
Solito E (2016).
Estrogen protects the blood–brain barrier from inflammation-induced disruption and increased lymphocyte trafficking. Brain, Behavior, and Immunity vol. 51, 212-222.
10.1016/j.bbi.2015.08.0202015

Yazid S, Gardner PJ, Carvalho L, Chu CJ, Flower RJ,
Solito E, Lee RWJ, Ali RR and Dick AD (2015).
Annexin-A1 restricts Th17 cells and attenuates the severity of autoimmune disease. Journal of Autoimmunity vol. 58, 1-11.
10.1016/j.jaut.2014.12.0042014

Queiroz CJDS, Nakata CMDAG,
Solito E and Damazo AS (2014).
Relationship between HPV and the biomarkers annexin A1 and p53 in oropharyngeal cancer. Infect Agent Cancer vol. 9,
10.1186/1750-9378-9-13
Mauro C, De Rosa V, Marelli-Berg F and
Solito E (2014).
Metabolic syndrome and the immunological affair with the blood-brain barrier. Front Immunol vol. 5,
10.3389/fimmu.2014.006772013

Girol AP, Mimura KKO, Drewes CC, Bolonheis SM,
Solito E, Farsky SHP, Gil CD and Oliani SM (2013).
Anti-inflammatory mechanisms of the annexin A1 protein and its mimetic peptide Ac2-26 in models of ocular inflammation in vivo and in vitro. J Immunol vol. 190, (11) 5689-5701.
10.4049/jimmunol.1202030
Cristante E, McArthur S, Mauro C, Maggioli E, Romero IA, Wylezinska-Arridge M, Couraud PO, Lopez-Tremoleda J, Christian HC, Weksler BB, Malaspina A and
Solito E (2013).
Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications. Proc Natl Acad Sci U S A vol. 110, (3) 832-841.
10.1073/pnas.1209362110
Yazid S, Sinniah A,
Solito E, Calder V and Flower RJ (2013).
Anti-allergic cromones inhibit histamine and eicosanoid release from activated human and murine mast cells by releasing Annexin A1. Plos One vol. 8, (3)
10.1371/journal.pone.00589632012

Mehet DK, Philip J,
Solito E, Buckingham JC and John CD (2012).
Evidence from in vitro and in vivo studies showing that nuclear factor-κB within the pituitary folliculostellate cells and corticotrophs regulates adrenocorticotrophic hormone secretion in experimental endotoxaemia. J Neuroendocrinol vol. 24, (6) 862-873.
10.1111/j.1365-2826.2012.02285.x2010

McArthur S, Cristante E, Paterno M, Christian H, Roncaroli F, Gillies GE and
Solito E (2010).
Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. J Immunol vol. 185, (10) 6317-6328.
10.4049/jimmunol.1001095
Yazid S, Leoni G, Getting SJ, Cooper D,
Solito E,
Perretti M and Flower RJ (2010).
Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization. Arterioscler Thromb Vasc Biol vol. 30, (9) 1718-1724.
10.1161/ATVBAHA.110.2095362009

McArthur S, Yazid S, Christian H, Sirha R, Flower R, Buckingham J and
Solito E (2009).
Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization. Faseb J vol. 23, (11) 4000-4010.
10.1096/fj.09-131391
Yazid S,
Solito E, Christian H, McArthur S, Goulding N and Flower R (2009).
Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1. Biochem Pharmacol vol. 77, (12) 1814-1826.
10.1016/j.bcp.2009.03.0102008

Yazid S,
Solito E, Christian H, Goulding N and Flower R (2008).
Further studies on the rapid glucocorticoid effects in the U937 monocytic cell line and its potentiation by cromoglycate-like drugs. Fund Clin Pharmacol vol. 22, 47-47.
McArthur S, Prasongchean W, Gillies G and
Solito E (2008).
A critical role for the anti-inflammatory protein annexin A1 in microglial phagocytosis. Fund Clin Pharmacol vol. 22, 23-23.

Damazo AS, Flower RJ,
Solito E and Oliani SM (2008).
Annexin-A1 gene expression during liver development and post-translation modification after experimental endotoxemia. Inflamm Res vol. 57, (3) 97-103.
10.1007/s00011-007-7114-2
Hu NJ, Bradshaw J, Lauter H, Buckingham J,
Solito E and Hofmann A (2008).
Membrane-induced folding and structure of membrane-bound annexin A1 N-terminal peptides: Implications for annexin-induced membrane aggregation. Biophys J vol. 94, (5) 1773-1781.
10.1529/biophysj.107.119685
Solito E, McArthur S, Christian H, Gavins F, Buckingham JC and Gillies GE (2008).
Annexin A1 in the brain--undiscovered roles? Trends Pharmacol Sci vol. 29, (3) 135-142.
10.1016/j.tips.2007.12.0032007

John CD, Sahni V, Mehet D, Morris JF, Christian HC,
Perretti M, Flower RJ,
Solito E and Buckingham JC (2007).
Formyl peptide receptors and the regulation of ACTH secretion: targets for annexin A1, lipoxins, and bacterial peptides. Faseb J vol. 21, (4) 1037-1046.
10.1096/fj.06-7299com2006

Warne JP, John CD, Christian HC, Morris JF, Flower RJ, Sugden D,
Solito E, Gillies GE and Buckingham JC (2006).
Gene deletion reveals roles for annexin A1 in the regulation of lipolysis and IL-6 release in epididymal adipose tissue. Am J Physiol-Endoc M vol. 291, (6) E1264-E1273.
10.1152/ajpendo.00655.2005
Kamal AM, Hayhoe RPG, Paramasivam A, Cooper D, Flower RJ,
Solito E and
Perretti M (2006).
Antiflammin-2 activates the human formyl-peptide receptor like 1. Scientificworldjournal vol. 6, 1375-1384.
10.1100/tsw.2006.247
Buckingham J, John C,
Solito E, Flower R, Christian H and Morris J (2006).
Annexin 1: a mediator of glucocorticoid action at the neuroendocrine-immune interface. Acta Pharmacol Sin vol. 27, 1-1.

Solito E, Christian HC, Festa M, Mulla A, Tierney T, Flower RJ and Buckingham JC (2006).
Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface. Faseb J vol. 20, (9) 1498-1500.
10.1096/fj.05-5319fje
Petrella A, Festa M, Ercolino SF, Zerilli M, Stassi G,
Solito E and Parente L (2006).
Down-regulation of annexin-1 expression in thyroid cancers is associated with tumour aggressiveness. Acta Pharmacol Sin vol. 27, 65-65.
Solito E, Christian HC, Festa M, Mulla A, Tierney T, Flower RJ and Buckingham JC (2006).
Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface. Faseb J vol. 20, (9) 1498-+.
10.1096/fj.05-5139fje
Petrella A, Festa M, Ercolino SF, Zerilli M, Stassi G,
Solito E and Parente L (2006).
Annexin-1 downregulation in thyroid cancer correlates to the degree of tumor differentiation. Cancer Biol Ther vol. 5, (6) 643-647.
10.4161/cbt.5.6.2700
Rodrigues-Lisoni FC, Mehet DK, Peitl P, John CD, da Silva WA, Tajara E, Buckingham JC and
Solito E (2006).
In vitro and in vivo studies on CCR10 regulation by Annexin A1 (vol 580, pg 1431, 2006). Febs Lett vol. 580, (7) 1908-1908.
10.1016/j.febslet.2006.02.026
Hayhoe RPG, Kamal AM,
Solito E, Flower RJ, Cooper D and
Perretti M (2006).
Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement. Blood vol. 107, (5) 2123-2130.
10.1182/blood-2005-08-3099
Rodrigues-Lisoni FC, Mehet DK, Peitl P, John CD, da Silva Júnior WA, Tajara E, Buckingham JC and
Solito E (2006).
In vitro and in vivo studies on CCR10 regulation by Annexin A1. Febs Lett vol. 580, (5) 1431-1438.
10.1016/j.febslet.2006.01.0722005

Petrella A, Festa M, Ercolino SF, Zerilli M, Stassi G,
Solito E and Parente L (2005).
Induction of annexin-1 during TRAIL-induced apoptosis in thyroid carcinoma cells. Cell Death Differ vol. 12, (10) 1358-1360.
10.1038/sj.cdd.4401645
Mulla A, Leroux C,
Solito E and Buckingham JC (2005).
Correlation between the antiinflammatory protein annexin 1 (lipocortin 1) and serum cortisol in subjects with normal and dysregulated adrenal function. J Clin Endocrinol Metab vol. 90, (1) 557-562.
10.1210/jc.2004-12302004

John CD, Christian HC, Morris JF, Flower RJ,
Solito E and Buckingham JC (2004).
Annexin 1 and the regulation of endocrine function. Trends Endocrin Met vol. 15, (3) 103-109.
10.1016/j.tem.2004.02.001
Mulla A, Christian HC,
Solito E, Mendoza N, Morris JF and Buckingham JC (2004).
Expression, subcellular localization and phosphorylation status of annexins 1 and 5 in human pituitary adenomas and a growth hormone-secreting carcinoma. Clin Endocrinol (Oxf) vol. 60, (1) 107-119.
10.1111/j.1365-2265.2004.01936.x2003

Tierney T, Christian HC, Morris JF,
Solito E and Buckingham JC (2003).
Evidence from studies on co-cultures of TtT/GF and AtT20 cells that Annexin 1 acts as a paracrine or juxtacrine mediator of the early inhibitory effects of glucocorticoids on ACTH release. J Neuroendocrinol vol. 15, (12) 1134-1143.
10.1111/j.1365-2826.2003.01111.x
John CD, Christian HC, Morris JF, Flower RJ,
Solito E and Buckingham JC (2003).
Kinase-dependent regulation of the secretion of thyrotrophin and luteinizing hormone by glucocorticoids and annexin 1 peptides. J Neuroendocrinol vol. 15, (10) 946-957.
10.1046/j.1365-2826.2003.01081.x
de Coupade C,
Solito E and Levine JD (2003).
Dexamethasone enhances interaction of endogenous annexin 1 with L-selectin and triggers shedding of L-selectin in the monocytic cell line U-937. Br J Pharmacol vol. 140, (1) 133-145.
10.1038/sj.bjp.0705413
Buckingham JC,
Solito E, John C, Tierney T, Taylor A, Flower R, Christian H and Morris J (2003).
Annexin 1: a paracrine/juxtacrine mediator of glucorticoid action in the neuroendocrine system. Cell Biochem Funct vol. 21, (3) 217-221.
10.1002/cbf.1076
Solito E, Kamal A, Russo-Marie F, Buckingham JC, Marullo S and
Perretti M (2003).
A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils. Faseb J vol. 17, (9) 1544-+.
10.1096/fj.02-0941fje
Croxtall JD, Gilroy DW,
Solito E, Choudhury Q, Ward BJ, Buckingham JC and Flower RJ (2003).
Attenuation of glucocorticoid functions in an Anx-A1-/- cell line. Biochem J vol. 371, (Pt 3) 927-935.
10.1042/BJ20021856
Solito E, Mulla A, Morris JF, Christian HC, Flower RJ and Buckingham JC (2003).
Dexamethasone induces rapid serine-phosphorylation and membrane translocation of annexin 1 in a human folliculostellate cell line via a novel nongenomic mechanism involving the glucocorticoid receptor, protein kinase c, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase. Endocrinology vol. 144, (4) 1164-1174.
10.1210/en.2002-220592
FLOWER RJ, John C,
Solito E, Morris J, Tierney T, Taylor A, Christian H and Buckingham JC (2003).
Annexin 1: a paracrine/juxtacrine mediator of glucorticoid action in the neuroendocrine system. Cell Biochemistry and Function. vol. 21, (3) 217-221.
10.1002/cbf.1076
FLOWER RJ, Morris JF, Christian HC, Buckingham JC,
Solito E and John CD (2003).
Kinase-Dependent Regulation of the Secretion of Thyrotrophin and Luteinizing Hormone By Glucocorticoids and Annexin 1 Peptides. J Neuroendocrinol. vol. 15, (10) 946-957.
10.1046/j.1365-2826.2003.01081.x2002
Perretti M, Chiang N, La M, Fierro IM, Marullo S, Getting SJ,
Solito E and Serhan CN (2002).
Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor. Nat Med vol. 8, (11) 1296-1302.
10.1038/nm786
Perretti M, Ingegnoli F, Wheller SK, Blades MC,
Solito E and Pitzalis C (2002).
Annexin 1 modulates monocyte-endothelial cell interaction in vitro and cell migration in vivo in the human SCID mouse transplantation model. J Immunol vol. 169, (4) 2085-2092.
10.4049/jimmunol.169.4.2085
Mulla A, Buckingham JC and
Solito E (2002).
LPS acts via IL-6 and IL-1 to modulate the expression and phosphorylation of annexin 1 in cell lines derived from the putative microglia of the neuroendocrine system. Brit J Pharmacol vol. 135,
Solito E, Mulla A and Buckingham JC (2002).
Dexamethasone induces serine phosphorylation of annexin 1: Involvement of PKC and PI3-kinase. Brit J Pharmacol vol. 135,

FLOWER RJ, Buckingham J, Christian H,
Solito E, John C, Cover P and Morris J (2002).
Annexin 1-dependent actions of glucocorticoids in the anterior pituitary gland: roles of the N-terminal domain and protein kinase C. Endocrinology. vol. 143, (8) 3060-3070.
10.1210/endo.143.8.89652001

Kamal AM, Smith SF, De Silva Wijayasinghe M,
Solito E and Corrigan CJ (2001).
An annexin 1 (ANXA1)-derived peptide inhibits prototype antigen-driven human T cell Th1 and Th2 responses in vitro. Clin Exp Allergy vol. 31, (7) 1116-1125.
10.1046/j.1365-2222.2001.01137.x
Perretti M, Getting SJ,
Solito E, Murphy PM and Gao JL (2001).
Involvement of the receptor for formylated peptides in the in vivo anti-migratory actions of annexin 1 and its mimetics. Am J Pathol vol. 158, (6) 1969-1973.
10.1016/S0002-9440(10)64667-6
John CD,
Solito E, Mulla A, Morris JF, Flower RJ and Buckingham JC (2001).
Dexamethasone induces serine phosphorylation of annexin 1 in pituitary cells and suppresses ACTH release by a PKC-dependent mechanism. Brit J Pharmacol vol. 133, U20-U20.
Solito E, de Coupade C, Canaider S, Goulding NJ and
Perretti M (2001).
Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation. Brit J Pharmacol vol. 133, (2) 217-228.
10.1038/sj.bjp.07040542000
Solito E, Tissot M, Russo-Marie F and Marullo S (2000).
Extracellular annexin-1 accelerates apoptosis of human polymorphonuclears neutrophils. Mol Biol Cell vol. 11, 462A-463A.

D'Amico M, Di Filippo C, La M, Solito E#27541#, McLean PG, Flower RJ#29483#, Oliani SM and Perretti M#20287# (2000).
Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocyte recruitment. Faseb J vol. 14, (13) 1867-1869.
10.1096/fj.99-0602fje
Solito E, Romero IA, Marullo S, Russo-Marie F and Weksler BB (2000).
Annexin 1 binds to U937 monocytic cells and inhibits their adhesion to microvascular endothelium: involvement of the alpha 4 beta 1 integrin. J Immunol vol. 165, (3) 1573-1581.
10.4049/jimmunol.165.3.1573
Mulla A, Christian H, Morris J, Mendoza N,
Solito E and Buckingham J (2000).
Expression of annexins 1 and 5 in human pituitary tumours. J Physiol-London vol. 525, 53P-54P.
Solito E, Tissot M, Russo-Marie F and Marullo S (2000).
Extracellular Annexin 1 induces apoptosis of human polymorphonuclear neutrophils. Faseb J vol. 14, (8) A1357-A1357.

Le Maire V,
Solito E, Russo-Marie F, Hernvann A, Le Marechal H, Ekindjian OG and Aussel C (2000).
System A neutral amino acid transporter regulation by interleukin-1beta in human osteoarthritic synovial cells: evidence for involvement of prostaglandin E(2) as a second messenger. J Cell Physiol vol. 183, (1) 65-73.
10.1002/(SICI)1097-4652(200004)183:1<65::AID-JCP8>3.0.CO;2-H
Canaider S,
Solito E, de Coupade C, Flower RJ, Russo-Marie F, Goulding NJ and
Perretti M (2000).
Increased apoptosis in U937 cells over-expressing lipocortin 1 (annexin I). Life Sci vol. 66, (18) PL265-PL270.
10.1016/s0024-3205(00)00500-2
Perretti M, Solito E#27541#, La M, Russo-Marie F, Marullo S, D'Amico M and Flower RJ (2000).
Annexin 1 activates human neutrophils: A mechanism for its anti-inflammatory in vivo effect. Faseb J vol. 14, (4) A8-A8.

de Coupade C, Gillet R, Bennoun M, Briand P, Russo-Marie F and
Solito E (2000).
Annexin 1 expression and phosphorylation are upregulated during liver regeneration and transformation in antithrombin III SV40 T large antigen transgenic mice. Hepatology vol. 31, (2) 371-380.
10.1002/hep.510310217
D'Amico M, Di Filippo C, Solito E#27541#, Flower RJ#29483# and Perretti M (2000).
Lipocortin 1 inhibits myocardial infarct by reducing local neutrophil infiltration. Brit J Pharmacol vol. 129, U56-U56.
1999

Gidon-Jeangirard C,
Solito E, Hofmann A, Russo-Marie F, Freyssinet JM and Martínez MC (1999).
Annexin V counteracts apoptosis while inducing Ca(2+) influx in human lymphocytic T cells. Biochem Biophys Res Commun vol. 265, (3) 709-715.
10.1006/bbrc.1999.1752
Canaider S,
Solito E, Goulding NJ, Flower RJ and Perretti M (1999).
Increased apoptosis in cells overexpressing lipocortin 1. Brit J Pharmacol vol. 126, U26-U26.

John CD, Cover PO, Taylor AD, Morris JF, Flower RJ,
Solito E and Buckingham JC (1999).
Evidence from in vivo and in vitro studies that the inhibitory actions of lipocortin 1 on anterior pituitary function require amino acid residues 13-26. Brit J Pharmacol vol. 126, U74-U74.

Raguenes-Nicol C, Russo-Marie F, Domage G, Diab N,
Solito E, Dray F, Mace JL and Streichenberger G (1999).
Anti-inflammatory mechanism of alminoprofen: action on the phospholipid metabolism pathway. Biochem Pharmacol vol. 57, (4) 433-443.
10.1016/s0006-2952(98)00312-8
Raugei G, Degl'Innocenti D, Chiarugi P, Solito E#27541#, Modesti A and Ramponi G (1999).
Preferential accumulation of muscle type acylphosphatase in the nucleus during differentiation. Biochem Mol Biol Int vol. 47, (1) 127-136.
10.1080/152165499002011231998

Lim LH,
Solito E, Russo-Marie F, Flower RJ and
Perretti M (1998).
Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1. Proc Natl Acad Sci U S A vol. 95, (24) 14535-14539.
10.1073/pnas.95.24.14535
Solito E, Raguenes-Nicol C, de Coupade C, Bisagni-Faure A and Russo-Marie F (1998).
U937 cells deprived of endogenous annexin 1 demonstrate an increased PLA2 activity. Br J Pharmacol vol. 124, (8) 1675-1683.
10.1038/sj.bjp.0701991
Solito E, de Coupade C, Parente L, Flower RJ and Russo-Marie F (1998).
IL-6 stimulates annexin 1 expression and translocation and suggests a new biological role as class II acute phase protein. Cytokine vol. 10, (7) 514-521.
10.1006/cyto.1997.0325
Solito E, de Coupade C, Parente L, Flower RJ and Russo-Marie F (1998).
Human annexin 1 is highly expressed during the differentiation of the epithelial cell line A 549: involvement of nuclear factor interleukin 6 in phorbol ester induction of annexin 1. Cell Growth Differ vol. 9, (4) 327-336.

Dubois T, Mira JP, Feliers D,
Solito E, Russo-Marie F and Oudinet JP (1998).
Annexin V inhibits protein kinase C activity via a mechanism of phospholipid sequestration. Biochem J vol. 330 ( Pt 3), 1277-1282.
10.1042/bj33012771997

Lim LHK, Getting SJ, Das AM,
Solito E, Flower RJ and Perretti M (1997).
Inhibition of neutrophil : endothelium interaction in murine post-capillary venules by lipocortin 1. Brit J Pharmacol vol. 122, U54-U54.

Voermans PH, Go KG, ter Horst GJ, Ruiters MH,
Solito E and Parente L (1997).
Expression of annexin and annexin-mRNA in rat brain under influence of steroid drugs. Acta Neurochir Suppl vol. 70, 222-224.
10.1007/978-3-7091-6837-0_681996

Cifone MG, Cironi L, Roncaioli P, Martinotti S, Toniato E, Cilenti L, Botti D,
Solito E, Parente L and Santoni A (1996).
Phospholipase A(2) activity and calpactin I levels in rat lymphokine-activated killer cells: Correlation with the cytotoxic activity. Cell Immunol vol. 170, (2) 274-282.
10.1006/cimm.1996.0161
Ambrosetti DC, Palla E, Mirtella A, Galeotti C,
Solito E, Navarra P, Parente L and Melli M (1996).
Synthetic alleles at position 121 define a functional domain of human interleukin-1 beta. Eur J Biochem vol. 238, (2) 308-316.
10.1111/j.1432-1033.1996.0308z.x
Voermans PH, Go KG, Horst GJ, Ruiters MH,
Solito E and Parente L (1996).
Induction of annexin-1 at transcriptional and post-transcriptional level in rat brain by methylprednisolone and the 21-aminosteroid U74389F. Mediators Inflamm vol. 5, (5) 370-378.
10.1155/S09629351960005311994
Solito E, Nuti S and Parente L (1994).
Dexamethasone-induced translocation of lipocortin (annexin) 1 to the cell membrane of U-937 cells. Br J Pharmacol vol. 112, (2) 347-348.
10.1111/j.1476-5381.1994.tb13075.x
Go KG, Zuiderveen F, De Ley L, Ter Haar JG, Parente L,
Solito E and Molenaar WM (1994).
Effect of steroids on brain lipocortin immunoreactivity. Acta Neurochir Suppl (Wien) vol. 60, 101-103.
10.1007/978-3-7091-9334-1_26
Go KG, Ter Haar JG, de Ley L, Zuiderveen F, Parente L,
Solito E and Molenaar WM (1994).
The effect of steroid treatment on lipocortin immunoreactivity of rat brain. Mediators Inflamm vol. 3, (3) 177-180.
10.1155/S0962935194000232
GO KG, ZUIDERVEEN F, DELEY L, TERHAAR JG, PARENTE L,
SOLITO E and MOLENAAR WM (1994).
EFFECT OF STEROIDS ON BRAIN LIPOCORTIN IMMUNOREACTIVITY. Acta Neurochir 101-103.

PARENTE L, NUTI S and
SOLITO E (1994).
DEXAMETHASONE INDUCES THE TRANSLOCATION OF LIPOCORTIN-1 TO THE MEMBRANE OF HUMAN MONOCYTIC U-937 CELLS. Brit J Pharmacol vol. 111, P72-P72.
SOLITO E, PALLA E, BENSI G, FASSINA G, MELLI M and PARENTE L (1994).
IDENTIFICATION OF ACTIVE-SITES OF INTERLEUKIN-1-BETA BY LOOP SUBSTITUTION AND SITE-DIRECTED MUTAGENESIS. Brit J Pharmacol vol. 111, P31-P31.
1993

De Caterina R, Sicari R, Giannessi D, Paggiaro PL, Paoletti P, Lazzerini G, Bernini W,
Solito E and Parente L (1993).
Macrophage-specific eicosanoid synthesis inhibition and lipocortin-1 induction by glucocorticoids. J Appl Physiol (1985) vol. 75, (6) 2368-2375.
10.1152/jappl.1993.75.6.2368
Palla E, Bensi G,
Solito E, Buonamassa DT, Fassina G, Raugei G, Spano F, Galeotti C, Mora M and Domenighini M (1993).
Loop substitution as a tool to identify active sites of interleukin-1 beta. J Biol Chem vol. 268, (18) 13486-13492.

BECHERUCCI C, PERRETTI M,
SOLITO E, GALEOTTI CL and PARENTE L (1993).
CONCEIVABLE DIFFERENCE IN THE ANTIINFLAMMATORY MECHANISMS OF LIPOCORTIN-1 AND LIPOCORTIN-5. Mediat Inflamm vol. 2, (2) 109-113.
10.1155/S0962935193000158
Rubartelli A, Bajetto A, Bonifaci N, Di Blas E,
Solito E and Sitia R (1993).
A novel way to get out of the cell. Cytotechnology vol. 11 Suppl 1, S37-S40.
10.1007/bf00746049
Solito E, De Caterina R, Giannessi D, Paggiaro PL, Sicari R and Parente L (1993).
Studies on the induction of lipocortin-1 by glucocorticoids. Ann Ist Super Sanita vol. 29, (3) 391-394.

Becherucci C,
Perretti M,
Solito E, Galeotti CL and Parente L (1993).
Conceivable difference in the anti-inflammatory mechanisms of lipocortins 1 and 5. Mediators Inflamm vol. 2, (2) 109-113.
10.1155/S09629351930001581992

Parente L,
Solito E, Giannessi P, Paggiari P, Sicari R and De Caterina R (1992).
Inhibition of eicosanoid formation and lipocortin induction by glucocorticoids in human cell lines and in patients with inflammatory lung disease. Pharmacol Res vol. 26 Suppl 2, 44-45.
10.1016/1043-6618(92)90591-x
Solito E, Raugei G, Melli M and Parente L (1992).
Glucocorticoid effect on lipocortin mRNA expression in U-937 cells. Pharmacol Res vol. 25 Suppl 1, 13-14.
10.1016/1043-6618(92)90517-f
Perretti M,
Solito E and Parente L (1992).
Evidence that endogenous interleukin-1 is involved in leukocyte migration in acute experimental inflammation in rats and mice. Agents Actions vol. 35, (1-2) 71-78.
10.1007/BF019909541991
Solito E, Raugei G, Melli M and Parente L (1991).
Dexamethasone induces the expression of the mRNA of lipocortin 1 and 2 and the release of lipocortin 1 and 5 in differentiated, but not undifferentiated U-937 cells. Febs Lett vol. 291, (2) 238-244.
10.1016/0014-5793(91)81293-h
SOLITO E, RAUGEI G, MELLI M and PARENTE L (1991).
DEXAMETHASONE INDUCES THE EXPRESSION OF THE MESSENGER-RNA OF LIPOCORTIN-1 AND LIPOCORTIN-2 AND THE RELEASE OF LIPOCORTIN-1 AND LIPOCORTIN-5 IN DIFFERENTIATED, BUT NOT UNDIFFERENTIATED U-937 CELLS. Febs Lett vol. 291, (2) 238-244.
10.1016/0014-5793(91)81293-H
Solito E, Raugei G, Melli M and Parente L (1991).
Effect of dexamethasone and phorbol myristate acetate on lipocortin 1, 2 and 5 mRNA and protein synthesis. Adv Prostaglandin Thromboxane Leukot Res vol. 21A, 291-294.

Boraschi D, Villa L, Ghiara P, Tagliabue A, Mengozzi M,
Solito E, Parente L, Silvestri S, Van Damme J and Ghezzi P (1991).
Mechanism of acute toxicity of IL-1 beta in mice. Eur Cytokine Netw vol. 2, (1) 61-67.
SOLITO E, RAUGEI G, MELLI M and PARENTE L (1991).
EFFECT OF DEXAMETHASONE AND PHORBOL-MYRISTATE ACETATE ON LIPOCORTIN-1, LIPOCORTIN-2 AND LIPOCORTIN-5 MESSENGER-RNA AND PROTEIN-SYNTHESIS. Adv Prostag Thromb L vol. 21, 291-294.
1990

Parente L, Becherucci C,
Perretti M,
Solito E, Mugridge KG, Galeotti CL, Raugei G, Melli M and Sanso M (1990).
Are the lipocortins the second messengers of the anti-inflammatory action of glucocorticoids? Prog Clin Biol Res vol. 349, 55-68.
1989
1988
SOLITO E and PARENTE L (1988).
ACTIVATION OF PHOSPHOLIPASE-A2 BY INTERLEUKIN-1 IN HUMAN-FIBROBLASTS. Lymphokine Res vol. 7, (3) 261-261.
1985
Solito E, Busoni P and Bini L (1985).
[Relational perspective in a district service for the substance-dependent]. Minerva Psichiatr vol. 26, (3) 267-269.