Dr Emilie Marhuenda
PDRA
School of Engineering and Materials Science
Queen Mary University of London
Queen Mary University of London
Research
Cardiomyocyte, Mechanobiology, Heart Disease, Intercalated Discs, Cell-cell signaling, Mechanosensing
Publications
2024
Tunable electrospun scaffolds of polyacrylonitrile loaded with carbon nanotubes: from synthesis to biological applicationsFromager B, Cambedouzou J, Marhuenda E, Iskratsch T, Pinault M, Bakalara N, Cornu D
Chembiochem, Wiley vol. 25 (7)
12-03-2024
Vascularised cardiac spheroids-on-a-chip for testing the toxicity of therapeuticsDi Cio S, Marhuenda E, Haddrick M, Gautrot JE
Scientific Reports, Springer Nature vol. 14 (1)
09-02-2024
Sox9 Accelerates Vascular Aging by Regulating Extracellular Matrix Composition and StiffnessFaleeva M, Ahmad S, Theofilatos K, Lynham S, Watson G, Whitehead M, Marhuenda E, Iskratsch T et al.
Circulation Research, Ovid Technologies (Wolters Kluwer Health) vol. 134 (3), 307-324.
02-02-2024
2023
Hypertensive Pressure Mechanosensing Alone Triggers Lipid Droplet Accumulation and Transdifferentiation of Vascular Smooth Muscle Cells to Foam CellsSwiatlowska P, Tipping W, Marhuenda E, Severi P, Fomin V, Yang Z, Xiao Q, Graham D et al.
Advanced Science, Wiley vol. 11 (9)
25-12-2023
Recent Advances in Electrospun Fibers for Biological ApplicationsFromager B, Marhuenda E, Louis B, Bakalara N, Cambedouzou J, Cornu D
Macromol—a Journal of Macromolecular Research, Mdpi vol. 3 (3), 569-613.
16-08-2023
Lem2 is essential for cardiac development by maintaining nuclear integrityRoss JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D et al.
Cardiovascular Research, Oxford University Press (Oup) vol. 119 (11), 2074-2088.
17-04-2023
Photoelectrochemical imaging of single cardiomyocytes and monitoring of their action potentials through contact force manipulation of organoidsJacques R, Zhou B, Marhuenda E, Gorecki J, Das A, Iskratsch T, Krause S
Biosensors and Bioelectronics, Elsevier Bv vol. 223, 115024-115024.
01-03-2023
2022
Mechanoregulation of vascular smooth muscle cells phenotype in atherosclerosisSwiatlowska P, Sit B, Feng Z, Marhuenda E, Zhou X, Xiao Q, Shanahan C, Yu C-H et al.
Journal of Molecular and Cellular Cardiology, Elsevier Bv vol. 173, S41-S42.
01-12-2022
Crosstalk between cell-matrix and cell-cell signaling in cardiomyocyte mechanosensingMarhuenda E, Iskratsch T, Xanthis I
Journal of Molecular and Cellular Cardiology, Elsevier vol. 173
01-12-2022
The cardiomyocyte mechanical code – Mechanical imprinting of talin interactions regulate cardiomyocyte mechanosensing and functionMarhuenda E, Pandey P, Xanthis I, O'Neill C, Iskratsch T
Journal of Molecular and Cellular Cardiology, Elsevier vol. 173
01-12-2022
Regulation of cardiomyocyte adhesion and mechanosignalling through distinct nanoscale behaviour of integrin ligands mimicking healthy or fibrotic extracellular matrixHawkes W, Marhuenda E, Reynolds P, O'Neill C, Pandey P, Samuel Wilson DG, Freeley M, Huang D et al.
Philosophical Transactions of The Royal Society B: Biological Sciences, The Royal Society vol. 377 (1864)
03-10-2022
Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switchingSwiatlowska P, Sit B, Feng Z, Marhuenda E, Xanthis I, Zingaro S, Ward M, Zhou X et al.
Science Advances, American Association For The Advancement of Science (Aaas) vol. 8 (15)
15-04-2022
2021
Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensingMarhuenda E, Fabre C, Zhang C, Martin-Fernandez M, Iskratsch T, Saleh A, Bauchet L, Cambedouzou J et al.
Journal of Experimental &Amp; Clinical Cancer Research, Springer Science and Business Media Llc vol. 40 (1)
24-04-2021
Targeting Several Biologically Reported Targets of Glioblastoma Multiforme by Assaying 2D and 3D Cultured CellsSixto-López Y, Marhuenda E, García-Vazquez JB, Fragoso-Vazquez MJ, Rosales-Hernández MC, Zacarías-Lara O, Méndez-Luna D, Gómez-Vidal JA et al.
Cellular and Molecular Neurobiology, Springer Nature vol. 42 (6), 1909-1920.
19-03-2021
2020
Matrix stiffness and blood pressure together regulate vascular smooth muscle cell phenotype switchingSwiatlowska P, Sit B, Feng Z, Marhuenda E, Xanthis I, Zingaro S, Ward M, Zhou X et al.
28-12-2020
Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensingMarhuenda E, Fabre C, Zhang C, Martin-Fernandez M, Iskratsch T, Saleh A, Bauchet L, Cambedouzou J et al.
, Cold Spring Harbor Laboratory
26-09-2020
2019
A novel 3D nanofibre scaffold conserves the plasticity of glioblastoma stem cell invasion by regulating galectin-3 and integrin-β1 expressionSaleh A, Marhuenda E, Fabre C, Hassani Z, Weille JD, Boukhaddaoui H, Guelfi S, Maldonado IL et al.
Scientific Reports, Springer Nature vol. 9 (1)
10-10-2019