Dr Babatunde Okesola
PDRA
School of Engineering and Materials Science , Institute of Bioen
Queen Mary University of London
b.okesola@qmul.ac.ukQueen Mary University of London
Research
Multicomponent biomaterials, Self-assembing hydrogels, Bio-instructive materials, Tissue regeneration, Biomineralization, Oxygenating biomaterials
Interests
I’m interested in developing multicomponent synthetic extracellular niches for various in vitro models ranging from vascularised bone tissue-like constructs to sealing of the fetal membrane defects.Publications
Publications of specific relevance to Predictive in vitro Models2021
Costa E, Okesola BO, Thrasivoulou C, Becker DL, Deprest JA, David AL and Chowdhury TT (2021). Cx43 mediates changes in myofibroblast contraction and collagen release in human amniotic membrane defects after trauma. Scientific Reports vol. 11, (1) 10.1038/s41598-021-94767-4Ajovalasit A, Redondo-Gómez C, Sabatino MA, Okesola BO, Braun K, Mata A and Dispenza C (2021). Carboxylated-xyloglucan and peptide amphiphile co-assembly in wound healing. Regen Biomater vol. 8, (5) 10.1093/rb/rbab040Okesola BO, Mendoza-Martinez AK, Cidonio G, Derkus B, Boccorh DK, Osuna De La Peña D, Elsharkawy S, Wu Y, Dawson JI, Wark AW, Knani D, Adams DJ, Oreffo ROC and Mata A (2021). De Novo Design of Functional Coassembling Organic-Inorganic Hydrogels for Hierarchical Mineralization and Neovascularization. Acs Nano vol. 15, (7) 11202-11217. 10.1021/acsnano.0c09814Wu Y, Fortunato GM, Okesola BO, Brocchetti FLPD, Suntornnond R, Connelly J, De Maria C, Rodriguez-Cabello JC, Vozzi G, Wang W and Mata A (2021). An interfacial self-assembling bioink for the manufacturing of capillary-like structures with tuneable and anisotropic permeability. Biofabrication vol. 13, (3) 10.1088/1758-5090/abe4c3Barrett DW, Okesola BO, Costa E, Thrasivoulou C, Becker DL, Mata A, Deprest JA, David AL and Chowdhury TT (2021). Potential sealing and repair of human FM defects after trauma with peptide amphiphiles and Cx43 antisense. Prenatal Diagnosis vol. 41, (1) 89-99. 10.1002/pd.58262020
Derkus B, Okesola BO, BARRETT DW, D Este M, Chowdhury TT, Eglin D and Mata A (2020). Multicomponent hydrogels for the formation of vascularized bone-like constructs in vitro. Elsevier Acta Biomaterialia 10.1016/j.actbio.2020.03.025 (2020). Growth-Factor Free Multicomponent Nanocomposite Hydrogels That Stimulate Bone Formation. Advanced Functional Materials vol. 30, (14) 10.1002/adfm.201906205Wu Y, Wang W, Mata A, Pugno N, Azevedo H, Karabasov S and Titirici M-M (2020). Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices. Nature Research (Part of Springer Nature) Nature Communications 10.1038/s41467-020-14716-zOkesola BO, Lau HK, Derkus B, Boccorh DK, Wu Y, Wark AW, Kiick KL and Mata A (2020). Covalent co-assembly between resilin-like polypeptide and peptide amphiphile into hydrogels with controlled nanostructure and improved mechanical properties. Biomaterials Science vol. 8, (3) 846-857. 10.1039/c9bm01796h2019
Okesola BO, Wu Y, Derkus B, Gani S, Wu D, Knani D, Smith DK, Adams DJ and Mata A (2019). Supramolecular Self-Assembly To Control Structural and Biological Properties of Multicomponent Hydrogels., Editors: Nicolas J. American Chemical Society (Acs) Chemistry of Materials vol. 31, (19) 7883-7897. 10.1021/acs.chemmater.9b018822018
MATA A (2018). Multicomponent self-assembly as a tool to harness new properties from peptides and proteins in materials design. Royal Society of Chemistry Chemical Society Reviews 10.1039/C8CS00121AOkesola BO, Redondo-Gómez C and Mata A (2018). Multicomponent self-assembly: Supramolecular design of complex hydrogels for biomedical applications. Self-Assembling Biomaterials: Molecular Design, Characterization and Application in Biology and Medicine 10.1016/B978-0-08-102015-9.00019-8Okesola BO, Redondo-Gómez C and Mata A (2018). 18 Multicomponent self-assembly: Supramolecular design of complex hydrogels for biomedical applications. Self-Assembling Biomaterials 10.1016/b978-0-08-102015-9.00019-82016
Okesola BO and Smith DK (2016). Applying low-molecular weight supramolecular gelators in an environmental setting-self-assembled gels as smart materials for pollutant removal. Chemical Society Reviews vol. 45, (15) 4226-4251. 10.1039/c6cs00124fOkesola BO, Suravaram SK, Parkin A and Smith DK (2016). ChemInform Abstract: Selective Extraction and in situ Reduction of Precious Metal Salts from Model Waste to Generate Hybrid Gels with Embedded Electrocatalytic Nanoparticles. Cheminform vol. 47, (11) no-no. 10.1002/chin.201611228Okesola BO, Suravaram SK, Parkin A and Smith DK (2016). Selective Extraction and in Situ Reduction of Precious Metal Salts from Model Waste to Generate Hybrid Gels with Embedded Electrocatalytic Nanoparticles. Angewandte Chemie - International Edition vol. 55, (1) 183-187. 10.1002/anie.2015076842015
Okesola BO, Suravaram SK, Parkin A and Smith DK (2015). Selective Extraction and In Situ Reduction of Precious Metal Salts from Model Waste To Generate Hybrid Gels with Embedded Electrocatalytic Nanoparticles. Angewandte Chemie vol. 128, (1) 191-195. 10.1002/ange.201507684Okesola BO, Vieira VMP, Cornwell DJ, Whitelaw NK and Smith DK (2015). 1,3:2,4-Dibenzylidene-d-sorbitol (DBS) and its derivatives-efficient, versatile and industrially-relevant low-molecular-weight gelators with over 100 years of history and a bright future. Soft Matter vol. 11, (24) 4768-4787. 10.1039/c5sm00845jHowe EJ, Okesola BO and Smith DK (2015). Self-assembled sorbitol-derived supramolecular hydrogels for the controlled encapsulation and release of active pharmaceutical ingredients. Chemical Communications vol. 51, (35) 7451-7454. 10.1039/c5cc01868d2014
Cornwell DJ, Okesola BO and Smith DK (2014). Multidomain hybrid hydrogels: Spatially resolved photopatterned synthetic nanomaterials combining polymer and low-molecular-weight gelators. Angewandte Chemie - International Edition 10.1002/anie.201405098Cornwell DJ, Okesola BO and Smith DK (2014). Multidomain Hybrid Hydrogels: Spatially Resolved Photopatterned Synthetic Nanomaterials Combining Polymer and Low‐Molecular‐Weight Gelators. Angewandte Chemie vol. 126, (46) 12669-12673. 10.1002/ange.2014050982013
Okesola BO and Smith DK (2013). Versatile supramolecular pH-tolerant hydrogels which demonstrate pH-dependent selective adsorption of dyes from aqueous solution. Chemical Communications vol. 49, (95) 11164-11166. 10.1039/c3cc45969aCornwell DJ, Okesola BO and Smith DK (2013). Hybrid polymer and low molecular weight gels-dynamic two-component soft materials with both responsive and robust nanoscale networks. Soft Matter vol. 9, (36) 8730-8736. 10.1039/c3sm51967h