Christie IN, Theparambil SM, Braga A, Doronin M, Hosford PS, Brazhe A, Mascarenhas A, Nizari S, Hadjihambi A, Wells JA, Hobbs A, Semyanov A, Abramov AY, Angelova PR and Gourine AV (2023). Astrocytes produce nitric oxide via nitrite reduction in mitochondria to regulate cerebral blood flow during brain hypoxia. Elsevier  Cell Reports  vol. 42, (12) 10.1016/j.celrep.2023.113514

Aubdool AA, Moyes AJ, Perez-Ternero C, Tsui JC, Lu HS, Daugherty A and Hobbs AJ (2023). Abstract 15171: Endothelium-Derived C-Type Natriuretic Peptide Prevents the Development and Progression of Abdominal Aortic Aneurysm. Wolters Kluwer  Circulation  vol. 148, (Suppl_1) 10.1161/circ.148.suppl_1.15171

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Koesling D, Kuhn M, MacEwan D, Monie TP, Potter LR, Russwurm M, Schmidt HHHW, Stasch J-P and Waldman SA (2023). The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Wiley  British Journal of Pharmacology  vol. 180, (S2) s241-s288. 10.1111/bph.16180

Fato BR, de Alwis N, Hobbs AJ, Kaitu'u-Lino TJ, Bubb KJ and Hannan NJ (2023). PO3_08. C-type natriuretic peptide relaxes omental arteries in a new ex vivo model of preeclampsia. Elsevier  Pregnancy Hypertension  vol. 33, 10.1016/j.preghy.2023.07.048

Andresen H, Pérez‐Ternero C, Robinson J, Dickey DM, Hobbs AJ, Potter LR, Levy FO, Cataliotti A and Moltzau LR (2023). Novel enhancers of guanylyl cyclase‐A activity acting via allosteric modulation. Wiley  British Journal of Pharmacology  vol. 180, (24) 3254-3270. 10.1111/bph.16203

Dignam JP, Perez-Ternero C, Aubdool AA and Hobbs AJ (2023). C-Type Natriuretic Peptide Signalling Attenuates the Development of Pulmonary Hypertension and Right Ventricular Remodelling.

Beuve A, Brouckaert P, Burnett JC, Friebe A, Garthwaite J, Hobbs AJ, Koesling D, Kuhn M, Potter LR, Russwurm M, Schmidt HHHW, Stasch J-P and Waldman SA (2023). Receptor guanylyl cyclase (RGC) family in GtoPdb v.2023.1. University of Edinburgh  Iuphar/Bps Guide to Pharmacology Cite  vol. 2023, (1) 10.2218/gtopdb/f1022/2023.1

Perez-Ternero C, Pallier PN, Tremoleda JL, Delogu A, Fernandes C, Michael-Titus AT and Hobbs AJ (2022). C-type natriuretic peptide preserves central neurological function by maintaining blood-brain barrier integrity. Frontiers  Frontiers in Molecular Neuroscience  vol. 15, 10.3389/fnmol.2022.991112

Zarenkiewicz J, Perez-Ternero C, Kojasoy V, McGinity C, Khodade VS, Lin J, Tantillo DJ, Toscano JP, Hobbs AJ and Fukuto JM (2022). The reaction of hydropersulfides (RSSH) with S-nitrosothiols (RS-NO) and the biological/physiological implications. Elsevier  Free Radical Biology and Medicine  vol. 188, 459-467. 10.1016/j.freeradbiomed.2022.06.245

Perez-Ternero C, Aubdool AA, Makwana R, Sanger GJ, Stimson RH, Chan LF, Moyes AJ and Hobbs AJ (2022). C-type natriuretic peptide is a pivotal regulator of metabolic homeostasis. Proceedings of The National Academy of Sciences  Proceedings of The National Academy of Sciences of The United States of America  vol. 119, (13) 10.1073/pnas.2116470119

Smith RJ, Perez-Ternero C, Conole D, Martin C, Myers SH, Hobbs AJ and Selwood DL (2022). A Series of Substituted Bis-Aminotriazines Are Activators of the Natriuretic Peptide Receptor C. American Chemical Society (Acs)  Journal of Medicinal Chemistry  vol. 65, (7) 5495-5513. 10.1021/acs.jmedchem.1c01974

Fukuto JM, Perez-Ternero C, Zarenkiewicz J, Lin J, Hobbs AJ and Toscano JP (2022). Hydropersulfides (RSSH) and Nitric Oxide (NO) Signaling: Possible Effects on S-Nitrosothiols (RS-NO). Mdpi  Antioxidants  vol. 11, (1) 10.3390/antiox11010169

Scott TE, Qin CX, Drummond GR, Hobbs AJ and Kemp-Harper BK (2021). Innovative Anti-Inflammatory and Pro-resolving Strategies for Pulmonary Hypertension: High Blood Pressure Research Council of Australia Award 2019. Hypertension  vol. 78, (5) 1168-1184. 10.1161/HYPERTENSIONAHA.120.14525

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Kuhn M, MacEwan D, Monie TP, Papapetropoulos A, Potter LR, Schmidt HHHW, Szabo C and Waldman SA (2021). THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors. British Journal of Pharmacology  vol. 178, (S1) S264-S312. 10.1111/bph.15541

Beuve A, Brouckaert P, Burnett JC, Friebe A, Garthwaite J, Hobbs AJ, Koesling D, Kuhn M, Potter LR, Russwurm M, Schmidt HHHW, Stasch J-P and Waldman SA (2021). Receptor guanylyl cyclase (RGC) family in GtoPdb v.2021.3. Iuphar/Bps Guide to Pharmacology Cite  vol. 2021, (3) 10.2218/gtopdb/f1022/2021.3

Petraina A, Nogales C, Krahn T, Mucke H, Lüscher TF, Fischmeister R, Kass DA, Burnett JC, Hobbs AJ and Schmidt HHHW (2021). Cyclic GMP modulating drugs in cardiovascular diseases: mechanism-based network pharmacology. Oxford University Press (Oup)  Cardiovascular Research  vol. 118, (9) 2085-2102. 10.1093/cvr/cvab240

Grange RMH, Preedy MEJ, Renukanthan A, Dignam JP, Lowe VJ, Moyes AJ, Pérez‐Ternero C, Aubdool AA, Baliga RS and Hobbs AJ (2021). Multidrug resistance proteins preferentially regulate natriuretic peptide‐driven cGMP signalling in the heart and vasculature. Wiley  British Journal of Pharmacology  vol. 179, (11) 2443-2459. 10.1111/bph.15593

Dignam JP, Scott TE, Kemp‐Harper BK and Hobbs AJ (2021). Animal models of pulmonary hypertension: Getting to the heart of the problem. Wiley  British Journal of Pharmacology  vol. 179, (5) 811-837. 10.1111/bph.15444

Fukuto JM and Hobbs AJ (2020). A comparison of the chemical biology of hydropersulfides (RSSH) with other protective biological antioxidants and nucleophiles. Elsevier  Nitric Oxide  vol. 107, 46-57. 10.1016/j.niox.2020.11.004

Aziz Q, Chen J, Moyes AJ, Li Y, Anderson NA, Ang R, Aksentijevic D, Sebastian S, Hobbs AJ, Thiemermann C and Tinker A (2020). Vascular KATP channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia. Springer Science and Business Media Llc  Journal of Molecular Medicine  10.1007/s00109-020-01946-3

Beuve A, Brouckaert P, Burnett JC, Friebe A, Garthwaite J, Hobbs AJ, Koesling D, Kuhn M, Potter LR, Russwurm M, Schmidt HHHW, Stasch J-P and Waldman SA (2020). Receptor guanylyl cyclase (RGC) family (version 2020.3) in the IUPHAR/BPS Guide to Pharmacology Database. Iuphar/Bps Guide to Pharmacology Cite  vol. 2020, (3) 10.2218/gtopdb/f1022/2020.3

Armstrong P, Ferreira PM, Chan M, Lundberg Slingsby M, Crescente M, Shih C, Kirkby N, Hobbs A and Warner T (2020). Combination of cyclic nucleotide modulators with P2Y12 receptor antagonists as anti-platelet therapy. Wiley  Journal of Thrombosis and Haemostasis  10.1111/jth.14826

Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J, Bedi KC, Margulies KB, Sanz‐Moreno V, Hobbs A and Hodivala‐Dilke K (2019). Repurposing an anti‐cancer agent for the treatment of hypertrophic heart disease. Wiley  The Journal of Pathology  vol. 249, (4) 523-535. 10.1002/path.5340

Beuve A, Brouckaert P, Burnett JC, Friebe A, Garthwaite J, Hobbs AJ, Koesling D, Kuhn M, Potter LR, Russwurm M, Schmidt HHHW, Stasch J-P and Waldman SA (2019). Receptor guanylyl cyclase (RGC) family (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. Iuphar/Bps Guide to Pharmacology Cite  vol. 2019, (4) 10.2218/gtopdb/f1022/2019.4

Hobbs AJ (2019). Nitric oxide biology & pathobiology (3rd edition) editors: Louis Ignarro & Bruce Freeman. Elsevier  Nitric Oxide  vol. 90, 10.1016/j.niox.2018.10.005

Preedy MEJ, Baliga RS and Hobbs AJ (2019). Multiplicity of Nitric Oxide and Natriuretic Peptide Signalling in Heart Failure. Lippincott, Williams & Wilkins  Journal of Cardiovascular Pharmacology  10.1097/FJC.0000000000000724

Sandner P, Zimmer DP, Milne GT, Follmann M, Hobbs A and Stasch J-P (2019). Correction to: Soluble Guanylate Cyclase Stimulators and Activators. Springer Verlag  Handbook of Experimental Pharmacology  10.1007/164_2019_249

Moyes AJ and Hobbs AJ (2019). C-Type Natriuretic Peptide: A Multifaceted Paracrine Regulator in the Heart and Vasculature. Mdpi  International Journal of Molecular Sciences  vol. 20, (9) 10.3390/ijms20092281

Hobbs AJ, Moyes AJ, Baliga RS, Ghedia D, Ochiel R, Sylvestre Y, Doré CJ, Chowdhury K, Maclagan K, Quartly HL, Sofat R, Smit A, Schreiber BE, Coghlan GJ and MacAllister RJ (2019). Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double‐blind, placebo‐controlled, proof‐of‐concept trial. Wiley  British Journal of Pharmacology  vol. 176, (9) 1251-1267. 10.1111/bph.14621

Moyes AJ, Chu SM, Aubdool AA, Dukinfield MS, Margulies KB, Bedi KC, Hodivala-Dilke K, Baliga RS and Hobbs AJ (2019). C-type natriuretic peptide co-ordinates cardiac structure and function. Oxford University Press (Oup)  European Heart Journal  vol. 41, (9) 10.1093/eurheartj/ehz093

Sandner P, Zimmer DP, Milne GT, Follmann M, Hobbs A and Stasch J-P (2019). Soluble Guanylate Cyclase Stimulators and Activators. Handb Exp Pharmacol  10.1007/164_2018_197

Bubb KJ, Aubdool AA, Moyes AJ, Lewis S, Drayton JP, Tang O, Mehta V, Zachary IC, Abraham DJ, Tsui J and Hobbs AJ (2018). Endothelial C-Type Natriuretic Peptide is a Critical Regulator of Angiogenesis and Vascular Remodeling. Circulation  10.1161/CIRCULATIONAHA.118.036344

Conole D, Myers SH, Mota F, Hobbs AJ and Selwood DL (2018). Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands. Wiley  Chemical Biology & Drug Design  vol. 93, (6) 1011-1020. 10.1111/cbdd.13395

Baliga RS, Preedy MEJ, Dukinfield MS, Chu SM, Aubdool AA, Bubb KJ, Moyes AJ, Tones MA and Hobbs AJ (2018). Phosphodiesterase 2 inhibition preferentially promotes NO/guanylyl cyclase/cGMP signaling to reverse the development of heart failure. Proc Natl Acad Sci U S A  10.1073/pnas.1800996115

Scott TE, Kemp‐Harper BK and Hobbs AJ (2018). Inflammasomes: a novel therapeutic target in pulmonary hypertension? Wiley  British Journal of Pharmacology  vol. 176, (12) 1880-1896. 10.1111/bph.14375

Fukuto JM, Ignarro LJ, Nagy P, Wink DA, Kevil CG, Feelisch M, Cortese‐Krott MM, Bianco CL, Kumagai Y, Hobbs AJ, Lin J, Ida T and Akaike T (2018). Biological hydropersulfides and related polysulfides – a new concept and perspective in redox biology. Wiley  Febs Letters  vol. 592, (12) 2140-2152. 10.1002/1873-3468.13090

Barrese V, Stott JB, Figueiredo HB, Aubdool AA, Hobbs AJ, Jepps TA, McNeish AJ and Greenwood IA (2018). Angiotensin II Promotes KV7.4 Channels Degradation Through Reduced Interaction With HSP90 (Heat Shock Protein 90). Wolters Kluwer  Hypertension  vol. 71, (6) 1091-1100. 10.1161/hypertensionaha.118.11116

Motwani MP, Bennett F, Norris PC, Maini AA, George MJ, Newson J, Henderson A, Hobbs AJ, Tepper M, White B, Serhan CN, MacAllister R and Gilroy DW (2018). Potent Anti‐Inflammatory and Pro‐Resolving Effects of Anabasum in a Human Model of Self‐Resolving Acute Inflammation. Wiley  Clinical Pharmacology & Therapeutics  vol. 104, (4) 675-686. 10.1002/cpt.980

Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA, Abbracchio MP, Aldrich R, Al-Hosaini K, Arumugam TV, Attali B, Bäck M, Barnes NM, Bathgate R, Beart PM, Becirovic E, Bettler B, Biel M and Birdsall NJ (2017). THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview. British Journal of Pharmacology  vol. 174, S1-S16. 10.1111/bph.13882

Kapil V (2017). Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017. Bmc Pharmacol Toxicol  vol. 18, (Suppl 1) 64-64. 10.1186/s40360-017-0170-5

Ren M, Ng FL, Warren HR, Witkowska K, Baron M, Jia Z, Cabrera C, Zhang R, Mifsud B, Munroe PB, Xiao Q, Townsend-Nicholson A, Hobbs AJ, Ye S and Caulfield MJ (2017). The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle. Oxford University Press (Oup)  Human Molecular Genetics  vol. 27, (1) 199-210. 10.1093/hmg/ddx375

Villar IC, Bubb KJ, Moyes AJ, Steiness E, Gulbrandsen T, Levy FO and Hobbs AJ (2016). Functional pharmacological characterization of SER100 in cardiovascular health and disease. Wiley  Br J Pharmacol  10.1111/bph.13634

Ren M, Ng F, Witkowska K, Baron M, Townsend-Nicholson A, Xiao Q, Hobbs A, Ye S and Caulfield MJ (2016). [OP.7C.08] BLOOD-PRESSURE ASSOCIATED VARIANTS IN NPR3 AFFECT HUMAN VASCULAR SMOOTH MUSCLE CELLS PROLIFERATION AND CALCIUM RESPONSE TO ANGIOTENSIN II. Wolters Kluwer  Journal of Hypertension  vol. 34, (&NA;) 10.1097/01.hjh.0000491573.57396.0f

Hobbs AJ (2016). A Janus-Faced Role for Atrial Natriuretic Peptide in Myocardial Infarction? Circ Res  vol. 119, (2) 181-183. 10.1161/CIRCRESAHA.116.309119

Hobbs AJ (2016). Guanylyl cyclase can't stand the HETE. Am J Physiol Heart Circ Physiol  vol. 310, (11) H1608-H1610. 10.1152/ajpheart.00326.2016

Chen J, Kieswich J, Chiazza F, Moyes A, Gobbetti T, Purvis G, Salvatori D, Patel N, Perretti M, Hobbs A, Collino M, Yaqoob M and THIEMERMANN C (2016). IkB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD. American Society of Nephrology  Journal of The American Society of Nephrology  10.1681/ASN.2015060670

Moyes AJ, Stanford SC, Hosford PS, Hobbs AJ and Ramage AG (2016). Raised arterial blood pressure in neurokinin-1 receptor-deficient mice ( NK1R −/− ): evidence for a neural rather than a vascular mechanism. Experimental Physiology  vol. 101, (5) 588-598. 10.1113/EP085347

Oettrich JM, Dao VT, Frijhoff J, Kleikers PWM, Casas AI, Hobbs AJ and Schmidt HHHW (2016). Clinical Relevance of Cyclic GMP Modulators: A Translational Success Story of Network Pharmacology. Clinical Pharmacology & Therapeutics  vol. 99, (4) 360-362. 10.1002/cpt.336

Moyes AJ, Chu SM, Baliga RS and Hobbs AJ (2015). Abstract 19478: Endothelial and Cardiomyocyte -derived C-type Natriuretic Peptide Coordinate Heart Structure and Function. Wolters Kluwer  Circulation  vol. 132, (suppl_3) 10.1161/circ.132.suppl_3.19478

Sand CA and Hobbs AJ (2015). The nuances of NO synthase regulation in sepsis: Could targeting BH4 be the answer? Elsevier  Vascular Pharmacology  vol. 77, 35-37. 10.1016/j.vph.2015.10.008

Allen RMH, Renukanthan A, Bubb KJ, Villar IC, Moyes AJ, Baliga RS and Hobbs AJ (2015). Investigation of the role of multidrug resistance proteins (MRPs) in vascular homeostasis. Springer Nature  Bmc Pharmacology and Toxicology  vol. 16, (Suppl 1) 10.1186/2050-6511-16-s1-a33

Hobbs AJ (2015). Pivotal vascular homeostatic role for endothelium-derived C-type natriuretic peptide (CNP). Springer Nature  Bmc Pharmacology and Toxicology  vol. 16, (Suppl 1) 10.1186/2050-6511-16-s1-a27

Ren M, Ng FL, Witkowska K, Baron M, Townsend-Nicholson A, Xiao Q, Hobbs A, Ye S and Caulfield M (2015). Abstract P048: Blood-Pressure Associated Variants in Natriuretic Peptide Receptor C Affect Human Vascular Smooth Muscle Cells Proliferation and Calcium Flux in Response to Angiotensin II. Wolters Kluwer  Hypertension  vol. 66, (suppl_1) 10.1161/hyp.66.suppl_1.p048

Peake NJ, Bader DL, Vessillier S, Ramachandran M, Salter DM, Hobbs AJ and Chowdhury TT (2015). C-type natriuretic peptide signalling drives homeostatic effects in human chondrocytes. Elsevier  Biochemical and Biophysical Research Communications  vol. 465, (4) 784-789. 10.1016/j.bbrc.2015.08.087

O'Brien A, China L, Massey KA, Nicolaou A, Winstanley A, Newson J, Hobbs A, Audzevich T and Gilroy DW (2015). Bile duct‐ligated mice exhibit multiple phenotypic similarities to acute decompensation patients despite histological differences. Wiley  Liver International  vol. 36, (6) 837-846. 10.1111/liv.12876

Allen R, Renukanthan A, Bubb K, Villar I, Moyes A, Baliga R and Hobbs A (2015). Investigation of the Role of Multidrug Resistance Proteins (MRPs) in Vascular Homeostasis. Wiley  The Faseb Journal  vol. 29, (S1) 10.1096/fasebj.29.1_supplement.783.8

Peake N, Pavlov A, D'Souza A, Alfasahin I, Pingaan-Murphy B, Sukhurukov G, Hobbs A and Chowdhury T (2015). Polyelectrolyte microencapsules loaded with C-type natriuretic peptide protect cartilage from IL-1B induced damage. Elsevier  Osteoarthritis and Cartilage  vol. 23, a141-a142. 10.1016/j.joca.2015.02.881

Papapetropoulos A, Hobbs AJ and Topouzis S (2015). Translational promise for NO pathway. Wiley  British Journal of Pharmacology  vol. 172, (6) 1397-1414. 10.1111/bph.12980

Peake NJ, Pavlov AM, D'Souza A, Pingguan-Murphy B, Sukhorukov GB, Hobbs AJ and CHOWDHURY TT (2015). Controlled Release of C-Type Natriuretic Peptide by Microencapsulation Dampens Proinflammatory Effects Induced by IL-1β in Cartilage Explants. American Chemical Society  Biomacromolecules  10.1021/bm501575w

Bubb KJ, Hobbs AJ and Klinger JR (2015). Modulation of cGMP Synthesis and Metabolism. Diagnosis and Management of Pulmonary Hypertension  Springer Nature  10.1007/978-1-4939-2636-7_15

Ren M, Ng FL, Witkowska K, Baron M, Townsend-Nicholson A, Xiao Q, Hobbs A, Ye S and Caulfield M (2015). Blood-pressure associated variants in NPR3 affect human vascular smooth muscle cells proliferation and calcium response to angiotensin II. Journal of Human Hypertension  vol. 29, (10) 624-624.

Ono K, Akaike T, Sawa T, Kumagai Y, Wink DA, Tantillo DJ, Hobbs AJ, Nagy P, Xian M, Lin J and Fukuto JM (2014). Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: implications of their possible biological activity and utility. Free Radic Biol Med  vol. 77, 82-94. 10.1016/j.freeradbiomed.2014.09.007

Peake NJ, Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F and Chowdhury TT (2014). Role of C-type natriuretic peptide signalling in maintaining cartilage and bone function. Osteoarthritis Cartilage  vol. 22, (11) 1800-1807. 10.1016/j.joca.2014.07.018

Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ, Rebstock A-S, Worthington RJ, Simone MI, Mota F, Rivilla F, Vallejo S, Peiró C, Sánchez Ferrer CF, Djordjevic S, Caulfield MJ, MacAllister RJ, Selwood DL, Ahluwalia A and Hobbs AJ (2014). Endothelial C-type natriuretic peptide maintains vascular homeostasis. J Clin Invest  vol. 124, (9) 4039-4051. 10.1172/JCI74281

Bubb KJ, Trinder SL, Baliga RS, Patel J, Clapp LH, MacAllister RJ and Hobbs AJ (2014). Inhibition of phosphodiesterase 2 augments cGMP and cAMP signaling to ameliorate pulmonary hypertension. Circulation  vol. 130, (6) 496-507. 10.1161/CIRCULATIONAHA.114.009751

Baliga RS, Scotton CJ, Trinder SL, Chambers RC, MacAllister RJ and Hobbs AJ (2014). Intrinsic defence capacity and therapeutic potential of natriuretic peptides in pulmonary hypertension associated with lung fibrosis. Br J Pharmacol  vol. 171, (14) 3463-3475. 10.1111/bph.12694

Hobbs AJ (2014). Natriuretic peptide receptors and heart failure: to B or not to B blocked? Naunyn Schmiedebergs Arch Pharmacol  vol. 387, (1) 1-4. 10.1007/s00210-013-0946-0

Gonzales MA, Han H, Moyes A, Radinos A, Hobbs AJ, Coombs N, Oliver SRJ and Mascharak PK (2014). Light-triggered carbon monoxide delivery with Al-MCM-41-based nanoparticles bearing a designed manganese carbonyl complex. Journal of Materials Chemistry B  vol. 2, (15) 2107-2113. 10.1039/c3tb21309a

Alexander SPH, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ, Abul-Hasn N, Anderson CM, Anderson CMH, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJM, Boison D, Bonner TI, Brailsford L, Bröer S, Brown P and Calo G (2013). Overview. Wiley  British Journal of Pharmacology  vol. 170, (8) 1449-1458. 10.1111/bph.12444

Derrett-Smith EC, Dooley A, Gilbane AJ, Trinder SL, Khan K, Baliga R, Holmes AM, Hobbs AJ, Abraham D and Denton CP (2013). Endothelial injury in a transforming growth factor β-dependent mouse model of scleroderma induces pulmonary arterial hypertension. Arthritis Rheum  vol. 65, (11) 2928-2939. 10.1002/art.38078

Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S, Yousuf M, Benjamin N, Webb AJ, Caulfield MJ, Hobbs AJ and Ahluwalia A (2013). Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential. Hypertension  vol. 61, (5) 1091-1102. 10.1161/HYPERTENSIONAHA.111.00933

Baliga RS, Macallister RJ and Hobbs AJ (2013). Vasoactive peptides and the pathogenesis of pulmonary hypertension: role and potential therapeutic application. Handb Exp Pharmacol  vol. 218, 477-511. 10.1007/978-3-642-38664-0_19

Ahluwalia A and Hobbs AJ (2013). Letter by Ahluwalia and Hobbs Regarding Article, Nitrate-Nitrite-Nitric Oxide Pathway in Pulmonary Arterial Hypertension Therapeutics. Circulation  vol. 127, (2) E275-E275. 10.1161/CIRCULATIONAHA.112.118356

Sciarretta S, Marchitti S, Bianchi F, Moyes A, Barbato E, Di Castro S, Stanzione R, Cotugno M, Castello L, Calvieri C, Eberini I, Sadoshima J, Hobbs AJ, Volpe M and Rubattu S (2013). C2238 Atrial Natriuretic Peptide Molecular Variant Is Associated With Endothelial Damage and Dysfunction Through Natriuretic Peptide Receptor C Signaling. Circulation Research  vol. 112, (10) 1355-+. 10.1161/CIRCRESAHA.113.301325

Peake N, Su N, Ramachandran M, Achan P, Salter DM, Bader DL, Moyes AJ, Hobbs AJ and Chowdhury TT (2013). Natriuretic peptide receptors regulate cytoprotective effects in an ex vivo human 3D / bioreactor model. Bio Med Central  Arthritis Research and Therapy  vol. 15, (4) 10.1186/ar4253

Baliga RS, MacAllister RJ and Hobbs AJ (2013). Vasoactive Peptides and the Pathogenesis of Pulmonary Hypertension: Role and Potential Therapeutic Application. Pharmacotherapy of Pulmonary Hypertension  Springer Nature  10.1007/978-3-662-45805-1_19

Chan MV, Bubb KJ, Noyce A, Villar IC, Duchene J, Hobbs AJ, Scotland RS and Ahluwalia A (2012). Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation. Br J Pharmacol  vol. 167, (4) 805-817. 10.1111/j.1476-5381.2012.02012.x

Baliga RS, Milsom AB, Ghosh SM, Trinder SL, Macallister RJ, Ahluwalia A and Hobbs AJ (2012). Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase. Circulation  vol. 125, (23) 2922-2932. 10.1161/CIRCULATIONAHA.112.100586

Gonzalez MA, Yim MA, Cheng S, Moyes A, Hobbs AJ and Mascharak PK (2012). Manganese Carbonyls Bearing Tripodal Polypyridine Ligands as Photoactive Carbon Monoxide-Releasing Molecules. Inorganic Chemistry  vol. 51, (1) 601-608. 10.1021/ic2021287

Moyes AJ, Khambata RS, Ahluwalia A and Hobbs AJ (2012). Accelerated Atherogenesis and Diminished Vascular Integrity in Mice Lacking Endothelial C-Type Natriuretic Peptide. Circulation  vol. 126, (21)

Khambata RS, Panayiotou CM and Hobbs AJ (2011). Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide. Br J Pharmacol  vol. 164, (2b) 584-597. 10.1111/j.1476-5381.2011.01400.x

Pourcet B, Feig JE, Vengrenyuk Y, Hobbs AJ, Kepka-Lenhart D, Garabedian MJ, Morris SM, Fisher EA and Pineda-Torra I (2011). LXRα regulates macrophage arginase 1 through PU.1 and interferon regulatory factor 8. Circ Res  vol. 109, (5) 492-501. 10.1161/CIRCRESAHA.111.241810

Baliga RS, Trinder SL, Scotton CJ, Chambers RC, MacAllister RJ and Hobbs AJ (2011). Enhancing natriuretic peptide bioactivity prevents bleomycin-induced pulmonary fibrosis. Springer Nature  Bmc Pharmacology  vol. 11, (Suppl 1) 10.1186/1471-2210-11-s1-p3

Quinteiro FM, Gane P, Rebstock A-S, Worthington R, Simone M, Djordevic S, Hobbs A and Selwood D (2011). Design and development of novel non-peptide agonists at NPR-C. Springer Nature  Bmc Pharmacology  vol. 11, (Suppl 1) 10.1186/1471-2210-11-s1-p54

Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ and Ahluwalia A (2011). Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin. Arterioscler Thromb Vasc Biol  vol. 31, (5) 1075-1083. 10.1161/ATVBAHA.111.223545

Baliga RS, MacAllister RJ and Hobbs AJ (2011). New perspectives for the treatment of pulmonary hypertension. Br J Pharmacol  vol. 163, (1) 125-140. 10.1111/j.1476-5381.2010.01164.x

Gonzalez MA, Fry NL, Burt R, Davda R, Hobbs A and Mascharak PK (2011). Designed Iron Carbonyls as Carbon Monoxide (CO) Releasing Molecules: Rapid CO Release and Delivery to Myoglobin in Aqueous Buffer, and Vasorelaxation of Mouse Aorta. Inorg Chem  vol. 50, (7) 3127-3134. 10.1021/ic2000848

Kapil V, Benjamin N, Hobbs A and Ahluwalia A (2011). Response to Inorganic Nitrate for Blood Pressure Lowering? Hypertension  vol. 57, (2) E3-E3. 10.1161/HYPERTENSIONAHA.110.164814

Derrett-Smith EC, Dooley A, Baliga R, Hobbs A, MacAllister R, Abraham D and Denton CP (2010). Perturbed VEGF signalling within the pulmonary vasculature of a TGF beta dependent mouse model of systemic sclerosis. Clin Exp Rheumatol  vol. 28, (5) S63-S63.

Madhani M, Hall AR, Cuello F, Charles RL, Burgoyne JR, Fuller W, Hobbs AJ, Shattock MJ and Eaton P (2010). Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury. Am J Physiol-Heart C  vol. 299, (3) H827-H836. 10.1152/ajpheart.00129.2010

Panayiotou CM, Baliga R, Stidwill R, Taylor V, Singer M and Hobbs AJ (2010). Resistance to endotoxic shock in mice lacking natriuretic peptide receptor-A. Br J Pharmacol  vol. 160, (8) 2045-2054. 10.1111/j.1476-5381.2010.00830.x

Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, Arghandawi S, Pearl V, Benjamin N, Loukogeorgakis S, Macallister R, Hobbs AJ, Webb AJ and Ahluwalia A (2010). Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO. Hypertension  vol. 56, (2) 274-281. 10.1161/HYPERTENSIONAHA.110.153536

Milsom AB, Patel NSA, Mazzon E, Tripatara P, Storey A, Mota-Filipe H, Sepodes B, Webb AJ, Cuzzocrea S, Hobbs AJ, Thiemermann C and Ahluwalia A (2010). Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice. Nitric Oxide-Biol Ch  vol. 22, (2) 141-148. 10.1016/j.niox.2009.10.010

Lumsden NG, Khambata RS and Hobbs AJ (2010). C-type Natriuretic Peptide (CNP): Cardiovascular Roles and Potential as a Therapeutic Target. Curr Pharm Design  vol. 16, (37) 4080-4088.

Khambata RS, Panayiotou CM, Xiao F and Hobbs AJ (2010). The anti-atherogenic potential of C-type natriuretic peptide: Disparate regulation of endothelial and vascular smooth muscle cell proliferation via natriuretic peptide receptor-C. Faseb Journal  vol. 24, 10.1096/fasebj.24.1_supplement.573.4

Hobbs AJ and Stasch J-P (2010). Chapter 9 Soluble Guanylate Cyclase Allosteric Activation and Redox Regulation. Nitric Oxide  Elsevier  10.1016/b978-0-12-373866-0.00009-5

Hobbs AJ and Stasch JP (2010). Soluble Guanylate Cyclase. Allosteric Activation and Redox Regulation. Nitric Oxide  10.1016/B978-0-12-373866-0.00009-5

Lumsden NG, Khambata RS and Hobbs AJ (2010). C-type natriuretic peptide (CNP): cardiovascular roles and potential as a therapeutic target. Curr Pharm Des  vol. 16, (37) 4080-4088. 10.2174/138161210794519237

Duchene J, Cayla C, Vessillier S, Scotland R, Yamashiro K, Lecomte F, Syed I, Vo P, Marrelli A, Pitzalis C, Cipollone F, Schanstra J, Bascands J-L, Hobbs AJ, Perretti M and Ahluwalia A (2009). Laminar shear stress regulates endothelial kinin B1 receptor expression and function: potential implication in atherogenesis. Arterioscler Thromb Vasc Biol  vol. 29, (11) 1757-1763. 10.1161/ATVBAHA.109.191775

Miller TW, Cherney MM, Lee AJ, Francoleon NE, Farmer PJ, King SB, Hobbs AJ, Miranda KM, Burstyn JN and Fukuto JM (2009). The Effects of Nitroxyl (HNO) on Soluble Guanylate Cyclase Activity INTERACTIONS AT FERROUS HEME AND CYSTEINE THIOLS. J Biol Chem  vol. 284, (33) 21788-21796. 10.1074/jbc.M109.014282

Morris T, Stables M, Hobbs A, de Souza P, Colville-Nash P, Warner T, Newson J, Bellingan G and Gilroy DW (2009). Effects of Low-Dose Aspirin on Acute Inflammatory Responses in Humans. J Immunol  vol. 183, (3) 2089-2096. 10.4049/jimmunol.0900477

Kapil V, Rehman F, Arghandawi S, Milsom A, Benjamin N, Hobbs A, MacAllister R, Webb A and Ahluwalia A (2009). BLOOD PRESSURE LOWERING EFFECTS OF ORAL INORGANIC NITRATE VIA BIOCONVERSION TO NITRITE. Basic Clin Pharmacol  vol. 105, 31-31.

Baliga RS, Trinder S, Scotton CJ, Chambers RC, MacAllister RJ and Hobbs AJ (2009). Manipulating the natriuretic peptide system for the treatment of pulmonary hypertension. Springer Nature  Bmc Pharmacology  vol. 9, (Suppl 1) 10.1186/1471-2210-9-s1-p2

Okorie M, Akram F, Loukogeorgakis S, Webb A, Deanfield J, Benjamin N, Hobbs A, MacAllister R and Ahluwalia A (2009). ORAL INORGANIC NITRATE PROTECTS AGAINST ENDOTHELIAL ISCHAEMIA-REPERFUSION INJURY IN HUMANS. Basic Clin Pharmacol  vol. 105, 26-26.

Diller GP, Bedard E, Wort SJ, Gatzoulis MA, van Eijl S, Ali O, Wilkins MR, Wharton J, Okonko DO, Howard LS, Thum T, Bauersachs J, Gibbs JSR and Hobbs AJ (2009). Response to Letter Regarding Article, Circulating Endothelial Progenitor Cells in Patients With Eisenmenger Syndrome and Idiopathic Pulmonary Arterial Hypertension. Circulation  vol. 119, (9) E231-E231. 10.1161/CIRCULATIONAHA.108.816363

Hajihosseini MK, Ramasamy S, De Langhe S, Lana-Elola E, Rice D, Rio LQ, Kelly R, Sharpe J and Bellusci S (2009). Involvement of Fibroblast growth factor 10 (Fgf10) in the anterior-posterior patterning and specification of muscle and tendon progenitors in the developing mouse limbs. Faseb Journal  vol. 23,

Hobbs AJ, Gane P, Lumsden N, Nobles M, Rebstock A-S, Simone M, Villar I, Worthington R, Xiao F, Ahluwalia A and Selwood D (2009). Design and development of novel non-peptide agonists at natriuretic peptide receptor-C. Faseb Journal  vol. 23, 10.1096/fasebj.23.1_supplement.756.8

Stasch J-P and Hobbs AJ (2009). NO-Independent, Haem-Dependent Soluble Guanylate Cyclase Stimulators. Cgmp: Generators, Effectors and Therapeutic Implications  Springer Nature  10.1007/978-3-540-68964-5_13

Webb AJ, Milsom AB, Rathod KS, Chu WL, Qureshi S, Lovell MJ, Lecomte FMJ, Perrett D, Raimondo C, Khoshbin E, Ahmed Z, Uppal R, Benjamin N, Hobbs AJ and Ahluwalia A (2008). Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase. Circ Res  vol. 103, (9) 957-964. 10.1161/CIRCRESAHA.108.175810

Baliga RS, Zhao L, Madhani M, Lopez-Torondel B, Visintin C, Selwood D, Wilkins MR, MacAllister RJ and Hobbs AJ (2008). Synergy between natriuretic peptides and phosphodiesterase 5 inhibitors ameliorates pulmonary arterial hypertension. Am J Respir Crit Care Med  vol. 178, (8) 861-869. 10.1164/rccm.200801-121OC

Marro ML, Peiro C, Panayiotou CM, Baliga RS, Meurer S, Schmidt HHHW and Hobbs AJ (2008). Characterization of the human alpha(1)beta(1) soluble guanylyl cyclase promoter - Key role for NF-kappa B(p50) and CCAAT-binding factors in regulating expression of the nitric oxide receptor. J Biol Chem  vol. 283, (29) 20027-20036. 10.1074/jbc.M801223200

Diller GP, van Eijl S, Okonko DO, Howard LS, Ali O, Thum T, Wort SJ, Bedard E, Gibbs JSR, Bauersachs J, Hobbs AJ, Wilkins MR, Gatzoulis MA and Wharton J (2008). Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension. Circulation  vol. 117, (23) 3020-3030. 10.1161/CIRCULATIONAHA.108.769646

Villar IC, Hobbs AJ and Ahluwalia A (2008). Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor. J Endocrinol  vol. 197, (3) 447-462. 10.1677/JOE-08-0070

Morton J, Coles B, Wright K, Gallimore A, Morrow JD, Terry ES, Anning PB, Morgan BP, Dioszeghy V, Kuhn H, Chaitidis P, Hobbs AJ, Jones SA and O'Donnell VB (2008). Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFN gamma-dependent iNOS expression in the vasculature of healthy mice. Blood  vol. 111, (10) 5187-5194. 10.1182/blood-2007-10-117283

Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ and Ahluwalia A (2008). Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension  vol. 51, (3) 784-790. 10.1161/HYPERTENSIONAHA.107.103523

Panayiotou CM, Stidwill R, Taylor V, Singer M and Hobbs AJ (2008). Resistance to endotoxic shock in mice lacking natriuretic peptide receptor-A. Faseb Journal  vol. 22, 10.1096/fasebj.22.1_supplement.1129.15

Webb A, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin B, Macallister R, Hobbs A and Abluwalia A (2008). Acute blood pressure lowering and vasoprotective effects of dietary nitrate. Faseb Journal  vol. 22, 10.1096/fasebj.22.1_supplement.737.30

Panayiotou CM and Hobbs AJ (2007). NPR-A gene deletion reverses vascular dysfunction associated with sepsis. Springer Nature  Bmc Pharmacology  vol. 7, (Suppl 1) 10.1186/1471-2210-7-s1-p44

Hobbs AJ (2007). Exploiting the natriuretic peptide system for the treatment of pulmonary hypertension. Springer Nature  Bmc Pharmacology  vol. 7, (Suppl 1) 10.1186/1471-2210-7-s1-s7

Baliga RS, Zhao L, Wilkins MR, MacAllister RJ and Hobbs AJ (2007). Selective modulation of ANP-dependent dilatation in the pulmonary vasculature by PDE 5 inhibitors: a novel combination therapy for pulmonary hypertension? Springer Nature  Bmc Pharmacology  vol. 7, (Suppl 1) 10.1186/1471-2210-7-s1-p2

Villar IC, Panayiotou CM, Sheraz A, Madhani M, Scotland RS, Nobles M, Kemp-Harper B, Ahluwalia A and Hobbs AJ (2007). Definitive role for natriuretic peptide receptor-C in mediating the vasorelaxant activity of C-type natriuretic peptide and endothelium-derived hyperpolarising factor. Cardiovasc Res  vol. 74, (3) 515-525. 10.1016/j.cardiores.2007.02.032

Paolocci N, Jackson MI, Lopez BE, Miranda K, Tocchetti CG, Wink DA, Hobbs AJ and Fukuto JM (2007). The pharmacology of nitroxyl (HNO) and its therapeutic potential: Not just the janus face of NO. Pharmacology & Therapeutics  vol. 113, (2) 442-458. 10.1016/j.pharmthera.2006.11.002

Madhani M, Patra AK, Miller TW, Eroy-Reveles AA, Hobbs AJ, Fukuto JM and Mascharak PK (2006). Biological activity of designed photolabile metal nitrosyls: light-dependent activation of soluble guanylate cyclase and vasorelaxant properties in rat aorta. J Med Chem  vol. 49, (25) 7325-7330. 10.1021/jm0604629

Madhani M, Okorie M, Hobbs AJ and MacAllister RJ (2006). Reciprocal regulation of human soluble and particulate guanylate cyclases in vivo. Br J Pharmacol  vol. 149, (6) 797-801. 10.1038/sj.bjp.0706920

Villar IC, Ahluwalia A and Hobbs AJ (2006). Distinct pathways regulate endothelium derived hyperpolarising factor-mediated responses in rat mesenteric arteries. Acta Pharmacol Sin  vol. 27, (9) 1276-1276.

Villar IC, Francis S, Webb A, Hobbs AJ and Ahluwalia A (2006). Novel aspects of endothelium-dependent regulation of vascular tone. Kidney Int  vol. 70, (5) 840-853. 10.1038/sj.ki.5001680

Marro M, Panayiotou C and Hobbs A (2006). Vascular inflammation modulates alpha 1 and beta 1 soluble guanylate cyclase promoter activity in human aortic smooth muscle cells (HASMCs). Acta Pharmacol Sin  vol. 27, 172-172.

Panayiotou CM and Hobbs AJ (2006). C-Type natriuretic peptide mediates ERK1/2 phosphorylation via Gi-coupled natriuretic peptide receptor-C in rat aortic smooth muscle cells. Acta Pharmacol Sin  vol. 27, 170-170.

Scotland RS, Cohen M, Foster P, Lovell M, Mathur A, Ahluwalia A and Hobbs AJ (2005). C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression. P Natl Acad Sci Usa  vol. 102, (40) 14452-14457. 10.1073/pnas.0504961102

Marro ML and Hobbs AJ (2005). Characterisation of human a1 and b1 soluble guanylate cyclase promoter activity in human aortic smooth muscle cells. Springer Nature  Bmc Pharmacology  vol. 5, (Suppl 1) 10.1186/1471-2210-5-s1-p34

Connelly L, Madhani M and Hobbs AJ (2005). Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo. J Biol Chem  vol. 280, (11) 10040-10046. 10.1074/jbc.M411991200

Ahluwalia A and Hobbs AJ (2005). Endothelium-derived C-type natriuretic peptide: more than just a hyperpolarizing factor. Trends Pharmacol Sci  vol. 26, (3) 162-167. 10.1016/j.tips.2005.01.005

Scotland RS, Madhani M, Chauhan S, Moncada S, Andresen J, Nilsson H, Hobbs AJ and Ahluwalia A (2005). Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice - Key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo. Circulation  vol. 111, (6) 796-803. 10.1161/01.CIR.0000155238.70797.4E

Scotland RS, Ahluwalia A and Hobbs AJ (2005). C-type natniuretic peptide in vascular physiology and disease. Pharmacol Therapeut  vol. 105, (2) 85-93. 10.1016/j.pharmthera.2004.08.011

Chauhan SD, Hobbs AJ and Ahluwalia A (2004). C-type natriuretic peptide: new candidate for endothelium-derived hyperpolarising factor. Int J Biochem Cell Biol  vol. 36, (10) 1878-1881. 10.1016/j.biocel.2003.09.009

Hobbs A, Foster P, Prescott C, Scotland R and Ahluwalia A (2004). Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury - Novel cardioprotective role for endothelium-derived C-type natriuretic peptide. Circulation  vol. 110, (10) 1231-1235. 10.1161/01.CIR.0000141802.29945.34

Ahluwalia A, MacAllister RJ and Hobbs AJ (2004). Vascular actions of natriuretic peptides. Cyclic GMP-dependent and -independent mechanisms. Basic Res Cardiol  vol. 99, (2) 83-89. 10.1007/s00395-004-0459-6

Ahluwalia A, Foster P, Scotland RS, McLean PG, Mathur A, Perretti M, Moncada S and Hobbs AJ (2004). Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment. P Natl Acad Sci Usa  vol. 101, (5) 1386-1391. 10.1073/pnas.0304264101

AHLUWALIA A, Hobbs A, Prescott C, Scotland R and Foster P (2004). Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide. Circulation  vol. 110, (10) 1231-1235. 10.1161/01.CIR.0000141802.29945.34

Hobbs AJ and Moncada S (2003). Antiplatelet properties of a novel, non-NO-based soluble guanylate cyclase activator, BAY 41-2272. Vascul Pharmacol  vol. 40, (3) 149-154. 10.1016/s1537-1891(03)00046-6

Madhani M, Scotland RS, MacAllister RJ and Hobbs AJ (2003). Vascular natriuretic peptide receptor-linked particulate guanylate cyclases are modulated by nitric oxide-cyclic GMP signalling. Br J Pharmacol  vol. 139, (7) 1289-1296. 10.1038/sj.bjp.0705365

Connelly L, Jacobs AT, Palacios-Callender M, Moncada S and Hobbs AJ (2003). Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression. J Biol Chem  vol. 278, (29) 26480-26487. 10.1074/jbc.M302238200

Madhani M, MacAllister R and Hobbs A (2003). Interactions between soluble guanylate cyclase and natriuretic peptide receptor-linked particulate guanylate cyclases in the mammalian vasculature. Springer Nature  Bmc News and Views  vol. 3, (S2) 10.1186/2048-4623-3-s2-p0033

Chauhan SD, Nilsson H, Ahluwalia A and Hobbs AJ (2003). Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor. P Natl Acad Sci Usa  vol. 100, (3) 1426-1431. 10.1073/pnas.0336365100

Kalsi JS, Rees RW, Hobbs AJ, Royle M, Kell PD, Ralph DJ, Moncada S and Cellek S (2003). BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro. J Urol  vol. 169, (2) 761-766. 10.1097/01.ju.0000043880.58140.69

KALSI JS, REES RW, HOBBS AJ, ROYLE M, KELL PD, RALPH DJ, MONCADA S and CELLEK S (2003). BAY41-2272, a Novel Nitric Oxide Independent Soluble Guanylate Cyclase Activator, Relaxes Human and Rabbit Corpus Cavernosum In Vitro. Wolters Kluwer  Journal of Urology  vol. 169, (2) 761-766. 10.1097/00005392-200302000-00081

AHLUWALIA A, Hobbs AJ, Seggara G, Chauhan SD, Vo PA and MacAllister RJ (2003). Protection against liposaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice. Faseb J  vol. 17, (6) 773-775. 10.1096/fj.02-0668fje

Hobbs AJ, Gladwin MT, Patel RP, Williams DLH and Butler AR (2002). Haemoglobin: NO transporter, NO inactivator or NOne of the above? Trends Pharmacol Sci  vol. 23, (9) 406-411. 10.1016/s0165-6147(02)02067-9

Hobbs AJ, Gladwin MT, Patel RP, Williams DLH and Butler AR (2002). Haernoglobin: NO transporter, NO inactivator or NOne of the above? Trends Pharmacol Sci  vol. 23, (9) 406-411. 10.1016/S0165-6147(02)02067-9

Hobbs AJ (2002). Soluble guanylate cyclase: an old therapeutic target re-visited. Br J Pharmacol  vol. 136, (5) 637-640. 10.1038/sj.bjp.0704779

Chauhan SD, MacAllister RJ, Hobbs AJ and Ahluwalia A (2002). Mechanisms underlying the vasorelaxant activity of C-type natriuretic peptide (CNP) in rat mesenteric resistance arteries. Faseb J  vol. 16, (4) A572-A572.

Connelly L, Palacios-Callender M, Ameixa C, Moncada S and Hobbs AJ (2001). Biphasic regulation of NF-kappa B activity underlies the pro- and anti-inflammatory actions of nitric oxide. J Immunol  vol. 166, (6) 3873-3881. 10.4049/jimmunol.166.6.3873

Hussain MB, MacAllister RJ and Hobbs AJ (2001). Reciprocal regulation of cGMP-mediated vasorelaxation by soluble and particulate guanylate cyclases. Am J Physiol Heart Circ Physiol  vol. 280, (3) H1151-H1159. 10.1152/ajpheart.2001.280.3.H1151

Selwood DL, Brummell DG, Budworth J, Burtin GE, Campbell RO, Chana SS, Charles IG, Fernandez PA, Glen RC, Goggin MC, Hobbs AJ, Kling MR, Liu Q, Madge DJ, Meillerais S, Powell KL, Reynolds K, Spacey GD, Stables JN, Tatlock MA, Wheeler KA, Wishart G and Woo CK (2001). Synthesis and biological evaluation of novel pyrazoles and indazoles as activators of the nitric oxide receptor, soluble guanylate cyclase. J Med Chem  vol. 44, (1) 78-93. 10.1021/jm001034k

Hobbs AJ (2000). Soluble guanylate cyclase. Taylor & Francis  Expert Opinion On Therapeutic Targets  vol. 4, (6) 735-749. 10.1517/14728222.4.6.735

Cavero M, Hobbs A, Madge D, Motherwell WB, Selwood D and Potier P (2000). Synthesis and biological evaluation of enantiopure thionitrites: the solid-phase synthesis and nitrosation of D-glutathione as a molecular probe. Bioorg Med Chem Lett  vol. 10, (7) 641-644. 10.1016/s0960-894x(00)00060-3

Hussain MB, MacAllister RJ and Hobbs AJ (2000). Regulation of cGMP-mediated vasorelaxation in mouse thoracic aorta: Interactions of the soluble and particulate guanylate cyclases. Brit J Pharmacol  vol. 129,

Shah S, Hobbs A, Singh R, Cuevas J, Ignarro LJ and Chaudhuri G (2000). Gastrointestinal motility during pregnancy: role of nitrergic component of NANC nerves. American Journal of Physiology-Regulatory Integrative and Comparative Physiology  vol. 279, (4) R1478-R1485. 10.1152/ajpregu.2000.279.4.R1478

Hussain MB, Hobbs AJ and MacAllister RJ (1999). Autoregulation of nitric oxide-soluble guanylate cyclase-cyclic GMP signalling in mouse thoracic aorta. Br J Pharmacol  vol. 128, (5) 1082-1088. 10.1038/sj.bjp.0702874

Wolzt M, MacAllister RJ, Davis D, Feelisch M, Moncada S, Vallance P and Hobbs AJ (1999). Biochemical characterization of S-nitrosohemoglobin. Mechanisms underlying synthesis, no release, and biological activity. J Biol Chem  vol. 274, (41) 28983-28990. 10.1074/jbc.274.41.28983

Hobbs AJ and Ignarro LJ (1999). Chemistry and Molecular Biology of Nitric Oxide Synthesis. The Haemodynamic Effects of Nitric Oxide  World Scientific Publishing  10.1142/9781848160781_0003

Hussain MB, Hobbs AJ and MacAllister RJ (1999). Enhanced sensitivity of the soluble guanylate cyclase/cyclic GMP system in the eNOS knockout mouse. Brit J Pharmacol  vol. 126, U41-U41.

Hobbs AJ, Higgs A and Moncada S (1999). Inhibition of nitric oxide synthase as a potential therapeutic target. Annu Rev Pharmacol Toxicol  vol. 39, 191-220. 10.1146/annurev.pharmtox.39.1.191

Hobbs AJ and Moncada S (1999). Inducible nitric oxide synthase and inflammation. Inducible Enzymes in The Inflammatory Response  Springer Nature  10.1007/978-3-0348-8747-2_2

Hobbs AJ (1997). Soluble guanylate cyclase: the forgotten sibling. Trends Pharmacol Sci  vol. 18, (12) 484-491. 10.1016/s0165-6147(97)01137-1

Hobbs AJ (1997). Soluble guanylate cyclase: the forgotten sibling. Elsevier  Trends in Pharmacological Sciences  vol. 18, (4) 484-491. 10.1016/s0165-6147(97)90687-8

Cohen GA, Hobbs AJ, Fitch RM, Zinner MJ, Chaudhuri G and Ignarro LJ (1996). Nitric oxide regulates endothelium-dependent vasodilator responses in rabbit hindquarters vascular bed in vivo. Am J Physiol  vol. 271, (1 Pt 2) H133-H139. 10.1152/ajpheart.1996.271.1.H133

Hobbs AJ and Ignarro LJ (1996). Nitric oxide cyclic GMP signal transduction system. Nitric Oxide, Pt B  vol. 269, 134-148. 10.1016/s0076-6879(96)69016-8

SHAH SN, CUEVAS JM, HOBBS AJ, WHANG E, IGNARRO LJ, ASHLEY SW and CHAUDHURI G (1995). ENHANCED ACTIONS OF NITRIC-OXIDE IN MODULATING GASTROINTESTINAL SMOOTH-MUSCLE FUNCTION DURING PREGNANCY. Gastroenterology  vol. 108, (4) A1246-A1246. 10.1016/0016-5085(95)29278-0

Griscavage JM, Hobbs AJ and Ignarro LJ (1995). Negative modulation of nitric oxide synthase by nitric oxide and nitroso compounds. Adv Pharmacol  vol. 34, 215-234. 10.1016/s1054-3589(08)61088-1

SHAH SN, CUEVAS JM, HOBBS AJ, WHANG E, ASHLEY SW, IGNARRO LJ and CHAUDHURI G (1995). CHANGES IN GASTROINTESTINAL SMOOTH-MUSCLE REACTIVITY DURING PREGNANCY MAY BE INDUCED BY NITRIC-OXIDE. Gastroenterology  vol. 108, (4) A688-A688. 10.1016/0016-5085(95)27063-9

HOBBS AJ, COHEN GA, FITCH RM, YIN TL, CHAUDHURI G and IGNARRO LJ (1995). DIFFERENTIAL INHIBITORY EFFECT OF L-NAME ON ENDOTHELIUM-DEPENDENT RELAXATION IN-VITRO AND IN-VIVO. Faseb Journal  vol. 9, (3) A328-A328.

SHAH SN, CUEVAS JM, HOBBS AJ, WHANG E, ASHLEY SW, IGNARRO LJ and CHAUDHURI G (1995). THE ROLE OF NITRIC-OXIDE IN MODULATING GASTROINTESTINAL SMOOTH-MUSCLE REACTIVITY DURING PREGNANCY. Faseb Journal  vol. 9, (3) A86-A86.

COHEN GA, HOBBS AJ, FITCH RM, ASHLEY SW, CRYER MH, CHAUDHURI G and IGNARRO LJ (1995). STIMULATED RELEASE OF NITRIC-OXIDE (NO) IS LINKED TO ALPHA-ADRENOCEPTOR ACTIVATION IN-VIVO. Faseb Journal  vol. 9, (3) A328-A328.

HOBBS AJ, FUKUTO JM and IGNARRO LJ (1994). FORMATION OF FREE NITRIC-OXIDE FROM L-ARGININE BY NITRIC-OXIDE SYNTHASE - DIRECT ENHANCEMENT OF GENERATION BY SUPEROXIDE-DISMUTASE. Proceedings of The National Academy of Sciences of The United States of America  vol. 91, (23) 10992-10996. 10.1073/pnas.91.23.10992

HOBBS AJ, GRISCAVAGE JM, ROGERS NE, BYRNS RE, FUKUTO JM and IGNARRO LJ (1994). FORMATION OF FREE NITRIC-OXIDE FROM L-ARGININE BY NITRIC-OXIDE SYNTHASE AND ENHANCEMENT OF GENERATION BY SUPEROXIDE-DISMUTASE. Faseb Journal  vol. 8, (4) A360-A360.

Fukuto JM, Hobbs AJ and Ignarro LJ (1993). Conversion of nitroxyl (HNO) to nitric oxide (NO) in biological systems: the role of physiological oxidants and relevance to the biological activity of HNO. Biochem Biophys Res Commun  vol. 196, (2) 707-713. 10.1006/bbrc.1993.2307

Brave SR, Bhat S, Hobbs AJ, Tucker JF and Gibson A (1993). The influence of L-NG-nitro-arginine on sympathetic nerve induced contraction and noradrenaline release in the rat isolated anococcygeus muscle. J Auton Pharmacol  vol. 13, (3) 219-225. 10.1111/j.1474-8673.1993.tb00269.x

Gibson A, Babbedge R, Brave SR, Hart SL, Hobbs AJ, Tucker JF, Wallace P and Moore PK (1992). An investigation of some S-nitrosothiols, and of hydroxy-arginine, on the mouse anococcygeus. Br J Pharmacol  vol. 107, (3) 715-721. 10.1111/j.1476-5381.1992.tb14512.x

Hobbs AJ, Tucker JF and Gibson A (1991). Differentiation by hydroquinone of relaxations induced by exogenous and endogenous nitrates in non-vascular smooth muscle: role of superoxide anions. Br J Pharmacol  vol. 104, (3) 645-650. 10.1111/j.1476-5381.1991.tb12483.x

Brave SR, Hobbs AJ, Gibson A and Tucker JF (1991). The influence of L-NG-nitro-arginine on field stimulation induced contractions and acetylcholine release in guinea pig isolated tracheal smooth muscle. Biochem Biophys Res Commun  vol. 179, (2) 1017-1022. 10.1016/0006-291x(91)91920-8

Mirzazadeh S, Hobbs AJ, Tucker JF and Gibson A (1991). Cyclic nucleotide content of the rat anococcygeus during relaxations induced by drugs or by non-adrenergic, non-cholinergic field stimulation. J Pharm Pharmacol  vol. 43, (4) 247-251. 10.1111/j.2042-7158.1991.tb06677.x

Hobbs AJ and Gibson A (1990). L-NG-nitro-arginine and its methyl ester are potent inhibitors of non-adrenergic, non-cholinergic transmission in the rat anococcygeus. Br J Pharmacol  vol. 100, (4) 749-752. 10.1111/j.1476-5381.1990.tb14086.x

Tucker JF, Brave SR, Charalambous L, Hobbs AJ and Gibson A (1990). L-NG-nitro arginine inhibits non-adrenergic, non-cholinergic relaxations of guinea-pig isolated tracheal smooth muscle. Br J Pharmacol  vol. 100, (4) 663-664. 10.1111/j.1476-5381.1990.tb14072.x

Gibson A, Hobbs AJ and Mirzazadeh S (1990). L-NG-nitroarginine is a potent inhibitor of non-adrenergic, non-cholinergic relaxations in the rat anococcygeus muscle. Elsevier  European Journal of Pharmacology  vol. 183, (5) 10.1016/0014-2999(90)92110-5

Gibson A, Mirzazadeh S, Hobbs AJ and Moore PK (1990). L-NG-monomethyl arginine and L-NG-nitro arginine inhibit non-adrenergic, non-cholinergic relaxation of the mouse anococcygeus muscle. Br J Pharmacol  vol. 99, (3) 602-606. 10.1111/j.1476-5381.1990.tb12976.x