A World-Leading Centre for Predictive in vitro Model Research, Training and Translation
Research with the Centre incorporates a wide range of model systems including 2D and 3D cell culture models, organoids, microphysiological systems, organ-on-a-chip technology, Non Animal Methods (NAMs), and other types of in vitro model.
With approximately 100 academic staff across the Faculty of Science and Engineering and the Faculty of Medicine and Dentistry, Queen Mary's Centre for Predictive in vitro Models is leading development and use of these complex in vitro models in partnership an extensive list of partners and industry affiliates.
Queen Mary provide leadership in this field hosting the annual UK symposium and engaging with Government, policy makers, funders, industry and other stake holders to support development and adoption of this transformative technology.
Events
| Mon 16 - Tue 17 Jun 2025 | 3rd Workshop on the European Commission roadmap towards phasing out animal testing for chemical safety assessments |
| Wed 18 - Fri 20 Jun 2025 | Tissue & Cell Engineering Society Conference 2025 |
 Fri 27 Jun 202510:00 - 16:00 | The UK Microsystems Network Launch |
| Sun 28 Sep - Wed 1 Oct 2025 | Bioengineered Tissue Systems & Models |
Recent Publications
- Engineering growth factor gradients to drive spatiotemporal tissue patterning in organ-on-a-chip systems
Hopkins T, Midha S, Grossemy S, Screen HRC, Wann AKT and Knight MM
Journal of Tissue Engineering vol. 16
18-04-2025 - Formyl-peptide receptor type 2 activation mitigates heart and lung damage in inflammatory arthritis
Margraf A, Chen J, Christoforou M, Claria-Ribas P, Henriques Schneider A, Cecconello C, Bu W, Imbert PRC, Wright TD, Russo S, Blacksell IA, Koenis DS, Dalli J, Lupisella JA, Wurtz NR, Garcia RA, Cooper D, Norling LV and Perretti M
Embo Molecular Medicine, Springer Nature, 1-31.
03-04-2025 - Endothelial c-REL orchestrates atherosclerosis at regions of disturbed flow through crosstalk with TXNIP-p38 and non-canonical NF-κB pathways
Ayllon BT, Bowden N, Souilhol C, Darwish H, Tian S, Duckworth C, Pritchard DM, Xu S, Sayers J, Francis S, Serbanovic-Canic J, Oakley F and Evans PC
Cardiovascular Research, Oxford University Press (Oup)
21-02-2025
Recent Grants
- The influence of a complex in vitro tumour microenvironment on cancer stem cells metastasis
Adrian Biddle and Ana Caetano
£547,066 National Centre for the Replacement, Refinement and Reduction of Animals in Research
01-05-2025 - 30-04-2028 - RAEng Research Chair Sept 2024 KA Hing
Karin Hing
£209,059 Royal Academy of Engineering
28-04-2025 - 27-04-2030 - Does endothelial EPAS1 protect arteries from atherosclerosis progression?
Paul Evans and Federica Marelli-Berg
£217,281 Barts and the London Charity
01-04-2025 - 31-03-2029