Miss Yu Hou

Yu Hou

PhD student (China Scholarship Council Studentship)

School of Engineering and Materials Science
Queen Mary University of London

Research

Arterial organ chip, Primary cilia mechanobiology, microfluidics

Underpinning Bioengineering

PhD Title

Organ-on-a-chip model of atherosclerosis based on the Emulate chip

Interests

My interest focus is developing an organ-on-a-chip model capable of stimulating arterial endothelial cells to replicate the artery and mimic the biomechanical environment that predisposes to atherosclerosis. After validating the atherosclerotic chip model in terms of primary cilia expression, I am also interested in testing whether it can prevent atherosclerosis.

Publications

solid heart iconPublications of specific relevance to Predictive <em>in vitro</em> Models

2022

YAP activation inhibits inflammatory signalling and cartilage breakdown associated with reduced primary cilia expression
Meng H, Fu S, Ferreira MB, Hou Y, Pearce OM, Gavara N and Knight MM
Osteoarthritis and Cartilage, Elsevier vol. 31 (5), 600-612.  
08-11-2022