Dr Weiqi Li

Weiqi Li
School of Engineering and Materials Science/Institute of Bioengi
Queen Mary University of London

Research

The endothelial glycocalyx, Actin cytoskeleton, Junctional complex, Cell mechanics, Directional cell migration, Angiogenesis

Interests

My research interest lies in the mechano-regulation of the endothelial glycocalyx in vitro, particularly looking into the interplay with the cytoskeletal system and junctional complex, with the use of super-resolution microscopy, confocal microscopy and atomic force microscopy.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2023

Advances in AI‐based cancer cytopathology
Yang Y, Guan S, Ou Z, Li W, Yan L, Situ B
Interdisciplinary Medicine, Wiley vol. 1 (3) 
01-07-2023

2021

The role of actomyosin in the regulation of syndecan-1 in hyperosmosis

Biochimica Et Biophysica Acta (Bba) - General Subjects, Elsevier Bv vol. 1865 (10), 129975-129975.  
01-10-2021
Hyaluronan (HA) Immobilized on Surfaces via Self-Assembled Monolayers of HA-Binding Peptide Modulates Endothelial Cell Spreading and Migration through Focal Adhesion

Acs Applied Materials &Amp; Interfaces, American Chemical Society (Acs) vol. 13 (22), 25792-25804.  
26-05-2021

2020

Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices

Nature Communications, Springer Science and Business Media Llc vol. 11 (1) 
04-03-2020

2019

Membrane tension regulates syndecan-1 expression through actin remodelling

Biochimica Et Biophysica Acta (Bba) - General Subjects, Elsevier Bv vol. 1863 (11), 129413-129413.  
01-11-2019
Mimicking the endothelial glycocalyx through the supramolecular presentation of hyaluronan on patterned surfaces

Faraday Discussions, Royal Society of Chemistry (Rsc) vol. 219, 168-182.  
01-01-2019

2018

Cobalt ions stimulate a fibrotic response through matrix remodelling, fibroblast contraction and release of pro-fibrotic signals from macrophages
Xu J, Nyga A, Li W, Zhang X, Gavara N, Knight MM, Shelton JC
European Cells and Materials vol. 36, 142-155.  
01-07-2018

2017

Structural alteration of the endothelial glycocalyx: contribution of the actin cytoskeleton

Biomechanics and Modeling in Mechanobiology, Springer Science and Business Media Llc vol. 17 (1), 147-158.  
14-08-2017

2015

3D imaging of cell interactions with electrospun PLGA nanofiber membranes for bone regeneration
Stachewicz U, Qiao T, Rawlinson SCF, Almeida FV, Li W-Q, Cattell M, Barber AH
Acta Biomaterialia, Elsevier/Science Direct vol. 27, 88-100.  
05-09-2015

2014

Converging Parallel Plate Flow Chambers for Studies on the Effect of the Spatial Gradient of Wall Shear Stress on Endothelial Cells

Journal of Biosciences and Medicines, Scientific Research Publishing, Inc. vol. 02 (02), 50-56.  
01-01-2014