Close

We use cookies to improve your experience of our website. Privacy Policy

Skip to main content
Menu

Dr Tina Chowdhury

Tina Chowdhury

Senior Lecturer in Regenerative Medicine

School of Engineering and Materials Science
Queen Mary University of London
+44 (0)20 7882 7560

www.sems.qmul.ac.uk/staff/t.t.chowdhury

Publications of specific relevance to Predictive in vitro Models

Publications

2020

Derkus B, Okesola BO, BARRETT DW, DEste M, Chowdhury TT, Eglin D and Mata A (2020). Multicomponent hydrogels for the formation of vascularized bone-like constructs in vitro. Elsevier  Acta Biomaterialia  10.1016/j.actbio.2020.03.025
Read JE, Luo D, Chowdhury TT, Flower RJ, Poston RN, Sukhorukov GB and Gould DJ (2020). Magnetically responsive layer-by-layer microcapsules can be retained in cells and under flow conditions to promote local drug release without triggering ROS production. Nanoscale  vol. 12, (14) 7735-7748. 10.1039/c9nr10329e
Dawsmith W, Ohtani N, Donnan R, Naftaly M, Dudley RA and Chowdhury TT (2020). Microwave Frequency Dependent Dielectric Properties of Blood as a Potential Technique to Measure Hydration. Institute of Electrical and Electronics Engineers (Ieee)  Ieee Access  1-1. 10.1109/access.2020.2977432
Barrett DW, Okesola BO, Costa E, Thrasivoulou C, Becker DL, Mata A, Deprest JA, David AL and Chowdhury TT (2020). Potential sealing and repair of human FM defects after trauma with peptide amphiphiles and Cx43 antisense. Prenatal Diagnosis  10.1002/pd.5826

2019

BARRETT DW, John RK, Thrasivoulou C, MATA A, Deprest JA, Becker DL, David AL and CHOWDHURY TINA (2019). Targeting mechanotransduction mechanisms and tissue weakening signals in the human amniotic membrane. Nature Publishing Group  Scientific Reports  10.1038/s41598-019-42379-4

2018

Engels AC, Joyeux L, Van der Merwe J, Jimenez J, Prapanus S, Barrett DW, Connon C, Chowdhury TT, David AL and Deprest J (2018). Tissuepatch is biocompatible and seals iatrogenic membrane defects in a rabbit model. Wiley  Prenatal Diagnosis  vol. 38, (2) 99-105. 10.1002/pd.5191

2017

Barrett DW, Kethees A, Thrasivoulou C, Mata A, Virasami A, Sebire NJ, Engels AC, Deprest JA, Becker DL, David AL and Chowdhury TT (2017). Trauma induces overexpression of Cx43 in human fetal membrane defects. Prenatal Diagnosis  vol. 37, (9) 899-906. 10.1002/pd.5104

2016

Barrett DW, David AL, Thrasivoulou C, Mata A, Becker DL, Engels AC, Deprest JA and Chowdhury TT (2016). Connexin 43 is overexpressed in human fetal membrane defects after fetoscopic surgery. Prenatal Diagnosis  vol. 36, (10) 942-952. 10.1002/pd.4917
Tilwani RK, Vessillier S, Pingguan-Murphy B, Lee DA, Bader DL and Chowdhury TT (2016). Oxygen tension modulates the effects of TNFα in compressed chondrocytes. Inflamm Res  10.1007/s00011-016-0991-5

2015

Hossain MA, Chowdhury T and Bagul A (2015). Imaging modalities for the in vivo surveillance of mesenchymal stromal cells. Journal of Tissue Engineering and Regenerative Medicine  vol. 9, (11) 1217-1224. 10.1002/term.1907
Peake NJ, Bader DL, Vessillier S, Ramachandran M, Salter DM, Hobbs AJ and Chowdhury TT (2015). C-type natriuretic peptide signalling drives homeostatic effects in human chondrocytes. Biochemical and Biophysical Research Communications  vol. 465, (4) 784-789. 10.1016/j.bbrc.2015.08.087
(2015). Polyelectrolyte microencapsules loaded with C-type natriuretic peptide protect cartilage from IL-1B induced damage. Osteoarthritis and Cartilage  vol. 23, a141-a142. 10.1016/j.joca.2015.02.881
(2015). Controlled Release of C-Type Natriuretic Peptide by Microencapsulation Dampens Proinflammatory Effects Induced by IL-1β in Cartilage Explants. American Chemical Society  Biomacromolecules  10.1021/bm501575w

2014

Peake NJ, Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F and Chowdhury TT (2014). Role of C-type natriuretic peptide signalling in maintaining cartilage and bone function. Osteoarthritis Cartilage  vol. 22, (11) 1800-1807. 10.1016/j.joca.2014.07.018
Peake NJ, Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F and CHOWDHURY TT (2014). Role of C-type natriuretic peptide signaling in maintaining cartilage and bone function. Elsevier/Science Direct  Osteoarthritis and Cartilage  vol. online edition, 10.1016/j.joca.2014.07.018
Hossain MA, CHOWDHURY TT and Bagul A (2014). Imaging modalities for the in vivo surveillance of mesenchymal stromal cells. Wiley  Journal of Tissue Engineering and Regenerative Medicine  10.1002/term.1907
Chowdhury B, David A, Bader D, Thrasivoulou C, Becker D and Chowdhury T (2014). PFM.37 Cyclic tensile strain increases PGE2 release leading to weakening of the human term amniotic membrane. Archives of Disease in Childhood - Fetal and Neonatal Edition  vol. 99, (Suppl 1) 10.1136/archdischild-2014-306576.267
Parker E, Vessillier S, Abas WW, Bader DL, Pinguaan-Murphy B and Chowdhury TT (2014). α5β1 integrin mediates compression-induced inhibition of catabolic effects induced by fibronectin fragments in an oxygen-dependent manner. Osteoarthritis and Cartilage  vol. 22, 10.1016/j.joca.2014.02.572
Chowdhury B, David AL, Thrasivoulou C, Becker DL, Bader DL and Chowdhury TT (2014). Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane. Placenta  vol. 35, (12) 1057-1064. 10.1016/j.placenta.2014.09.006

2013

Parker E, Vessillier S, Pinguaan-Murphy B, Wan Abas WAB, Bader DL and Chowdhury TT (2013). Low oxygen tension increased FN-f induced catabolic activities - response prevented with biomechanical signals. Biomed Central  Arthritis Research and Therapy  vol. 15, (5) R163-R163. 10.1186/ar4346
Akanji O, Salter DM and Chowdhury TT (2013). Optimisation of quantitative real-time PCR studies in cartilage mechanobiology. Pcr Technology. Current Innovations , Editors: Nolan T and Bustin SA. Crc Pressi Llc  10.1201/b14930-25
Parker E, Pinguuan-Murphy B, Bader DL and Chowdhury TT (2013). FN-f induced catabolic activities are dependent on oxygen tension in chondrocyte/agarose constructs subjected to biomechanical signals. Osteoarthritis and Cartilage  vol. 21, 10.1016/j.joca.2013.02.440
Hossain MA, Frampton AE, Chowdhury TT and Morsey M (2013). Biological vascular grafts for hemodialysis access. Informa Healthcare  Expert Rev Med Devices  vol. 2, (10) 171-175. 10.1586/erd.12.85
Peake N, Su N, Ramachandran M, Achan P, Salter DM, Bader DL, Moyes AJ, Hobbs AJ and Chowdhury TT (2013). Natriuretic peptide receptors regulate cytoprotective effects in an ex vivo human 3D / bioreactor model. Bio Med Central  Arthritis Research and Therapy  vol. 15, (4) 10.1186/ar4253

2012

CHOWDHURY TT, Tilwani RK and Bader DL (2012). Biomechanical conditioning enhanced matrix synthesis in nucleus pulposus cells cultured in agarase constructs with TGFβ., Editors: Goldsmith EC and Lin SK. Journal Functional Biomaterials  vol. 3, 23-26. 10.3390/jfb3010023

2011

Ramachandran M, Achan P, Salter DM, Bader DL and Chowdhury TT (2011). Biomechanical signals and the C-type natriuretic peptide counteract catabolic activities induced by IL-1β in chondrocyte/agarose constructs. Arthritis Research and Therapy  vol. 13, (5) 10.1186/ar3459
Bader DL, Salter DM and Chowdhury TT (2011). Biomechanical influence of cartilage homeostasis in health and disease. Arthritis  vol. 2011, 10.1155/2011/979032
Lee DA, Brand J, Salter D, Akanji O-O and Chowdhury TT (2011). Quantification of mRNA using real-time PCR and Western blot analysis of MAPK events in chondrocyte/agarose constructs. Methods Mol Biol  vol. 695, 77-97. 10.1007/978-1-60761-984-0_6

2010

Chowdhury TT, Schulz RM, Rai SS, Thuemmler CB, Wuestneck N, Bader A and Homandberg GA (2010). Biomechanical modulation of collagen fragment-induced anabolic and catabolic activities in chondrocyte/agarose constructs. Arthritis Research and Therapy  vol. 12, (3) 10.1186/ar3009
McGlashan SR, Knight MM, Chowdhury TT, Joshi P, Jensen CG, Kennedy S and Poole CA (2010). Mechanical loading modulates chondrocyte primary cilia incidence and length. Cell Biology International  vol. 34, (5) 441-446. 10.1042/CBI20090094
Akanji OO, Sakthithasan P, Salter DM and Chowdhury TT (2010). Dynamic compression alters NFκB activation and IκB-α expression in IL-1β-stimulated chondrocyte/agarose constructs. Inflammation Research  vol. 59, (1) 41-52. 10.1007/s00011-009-0068-9

2009

Akanji OO, Salter DM and Chowdhury TT (2009). 458 DYNAMIC COMPRESSION ALTERS NF?B ACTIVATION AND I?B-α EXPRESSION IN IL-1β STIMULATED CHONDROCYTE/AGAROSE CONSTRUCTS. Osteoarthritis and Cartilage  vol. 17, s245-s246. 10.1016/s1063-4584(09)60479-9
Raveenthiran SP and Chowdhury TT (2009). Dynamic compression inhibits fibronectin fragment induced iNOS and COX-2 expression in chondrocyte/agarose constructs. Biomechanics and Modeling in Mechanobiology  vol. 8, (4) 273-283. 10.1007/s10237-008-0134-1

2008

Chowdhury TT, Salter DM, Bader DL and Lee DA (2008). Signal transduction pathways involving p38 MAPK, JNK, NF kappa B and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1 beta and dynamic compression. Inflamm Res  vol. 57, (7) 306-313. 10.1007/s00011-007-7126-y
CHOWDHURY TT, Akanjii OO, Salter DM and Lee DA (2008). Dynamic compression influences IL-1β induced NO and PGE2 release, via alterations in iNOS and COX-2 activity. 5th International Symposium On Mechanobiology of Cartilage and Chondrocyte , Editors: Stoltz JF.
Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Bader DL, Salter DM and Lee DA (2008). Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs. Arthritis Res Ther  vol. 10, (2) 10.1186/ar2389
Chowdhury TT, Akanji OO, Salter DM, Bader DL and Lee DA (2008). Dynamic compression influences interleukin-1 beta-induced nitric oxide and prostaglandin E-2 release by articular chondrocytes via alterations in iNOS and COX-2 expression. Biorheology  vol. 45, (3-4) 257-274. 10.3233/BIR-2008-0474

2007

Chowdhury TT, Akanji OO, Arghandawi S, Salter DM, Bader DL and Lee DA (2007). 52 REAL-TIME PCR USING MOLECULAR BEACONS TO DETECT INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS SUBJECTED TO IL-1β AND DYNAMIC COMPRESSION. Osteoarthritis and Cartilage  vol. 15, c42-c43. 10.1016/s1063-4584(07)61688-4
Campbell JJ, Blain EJ, Chowdhury TT and Knight MM (2007). Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes. Biochemical and Biophysical Research Communications  vol. 361, (2) 329-334. 10.1016/j.bbrc.2007.06.185

2006

Chowdhury TT and Knight MM (2006). Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression. Journal of Cellular Physiology  vol. 209, (3) 845-853. 10.1002/jcp.20768
Chowdhury TT, Appleby RN, Salter DM, Bader DA and Lee DA (2006). Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes. Biomech Model Mechanobiol  vol. 5, (2-3) 192-201. 10.1007/s10237-006-0032-3
Chowdhury TT, Bader DL and Lee DA (2006). Anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated chondrocytes. Biochem Biophys Res Commun  vol. 339, (1) 241-247. 10.1016/j.bbrc.2005.11.016
CHOWDHURY TT, Bader DL and Lee DA (2006). Dynamic compression counteracts IL-1β induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Mechanobiology: Cartilage and Chondrocyte , Editors: Stoltz JF. Ios Press 
Chowdhury TT, Bader DL and Lee DA (2006). Dynamic compression counteracts IL-1beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Biorheology  vol. 43, (3,4) 413-429.

2005

Chowdhury TT, Bader DL and Lee DA (2005). Dynamic compression counteracts IL-1-induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Proceedings of The 2005 Summer Bioengineering Conference  vol. 2005, 251-252.
Chowdhury TT, Appleby RN, Salter DA, Bader DL and Lee DA (2005). Integrin mediated mechanotransduction in IL-1 stimulated bovine chondrocytes cultured in agarose constructs. Proceedings of The 2005 Summer Bioengineering Conference  vol. 2005, 545-546.
Chowdhury TT, Bader DL and Lee DA (2005). Dynamic compression counteracts IL-1β induced INOS and COX-2 activity by human chondrocytes cultured in agarose constructs. European Cells and Materials  vol. 10, (SUPPL.2)
Catuogno C, Chowdhury TT, Bader DL and Lee DA (2005). Dynamic compression influences the biochemical response of human mesenchymal stem cells cultured in agarose constructs. European Cells and Materials  vol. 10, (SUPPL.2)
Sudre L, Cheung F, Kevorkian L, Young DA, Darrah C, Donell ST, Shepstone L, Porter S, Brockbank S, Edwards DR, Parker AE, Clark IM, Boubriak OA, Urban JPG, Cui Z, Tew SR, Li Y, Tweats LM, Hawkins RE, Hardingham TE, Green D, Partridge KA, Leveque I, Mann S, Oreffo ROC, Ball SG, Kielty CM, Qin M, Tai G and Polak JM (2005). British society for matrix biology autumn meeting. International Journal of Experimental Pathology  vol. 86, (3) 10.1111/j.0959-9673.2005.00426.x

2004

Chowdhury TT, Salter DM, Bader DL and Lee DA (2004). Integrin-mediated mechanotransduction processes in TGFbeta-stimulated monolayer-expanded chondrocytes. Biochem Biophys Res Commun  vol. 318, (4) 873-881. 10.1016/j.bbrc.2004.04.107
Bryant SJ, Chowdhury TT, Lee DA, Bader DL and Anseth KS (2004). Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels. Ann Biomed Eng  vol. 32, (3) 407-417. 10.1023/b:abme.0000017535.00602.ca

2003

Chowdhury TT, Bader DL, Shelton JC and Lee DA (2003). Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression. Arch Biochem Biophys  vol. 417, (1) 105-111. 10.1016/s0003-9861(03)00340-0
Chowdhury TT, Bader DL and Lee DA (2003). Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE2 by superficial zone chondrocytes cultured in agarose constructs. Osteoarthritis Cartilage  vol. 11, (9) 688-696. 10.1016/s1063-4584(03)00149-3
Chowdhury TT, LEE DA, Salter DM, Shelton JC and Bader DL (2003). alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta-stimulated human chondrocyte / agarose constructs and subjected to dynamic compression. Osteoarthritis Cartilage  vol. 11, (Suppl 1) S2-S3.
Chowdhury TT, Shelton JC, Bader DL and LEE DA (2003). Control of mechanotrasduction processes in dynamically stimulated human and bovine chondrocytes cultured in agarose constructs. Internat. J. Artificial Organs  vol. 26, (9) 858-858.

2001

Chowdhury TT, Bader DL and Lee DA (2001). Dynamic compression inhibits the synthesis of nitric oxide and PGE(2) by IL-1beta-stimulated chondrocytes cultured in agarose constructs. Biochem Biophys Res Commun  vol. 285, (5) 1168-1174. 10.1006/bbrc.2001.5311

2000

Chowdhury TT, Bader DL and Lee DA (2000). Dynamic compression inhibits the synthesis of nitric oxide by IL-1β stimulated chondrocytes cultured in agarose constructs. Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell 

Grants

Grants of specific relevance to Predictive in vitro Models
DTP 2016-2017 Queen Mary, University of London
Chowdhury TT
£1,316,870 Engineering and Physical Sciences Research Council (30-09-2016 - 29-09-2021)
Abstract
Healing the fetal membrane
Chowdhury TT
£28,500 Rosetrees Trust (23-10-2014 - 22-10-2017)


Beneficial effect of CNP and mechanical loading in human cartilage
Chowdhury TT
£45,000 AO Foundation (09-09-2010 - 09-10-2013)