Publications

Publications of specific relevance to Predictive in vitro Models
2021

Costa E,
Okesola BO, Thrasivoulou C, Becker DL, Deprest JA, David AL and
Chowdhury TT (2021).
Cx43 mediates changes in myofibroblast contraction and collagen release in human amniotic membrane defects after trauma. Scientific Reports vol. 11, (1)
10.1038/s41598-021-94767-4
Meng H,
Chowdhury TT and Gavara N (2021).
The Mechanical Interplay Between Differentiating Mesenchymal Stem Cells and Gelatin-Based Substrates Measured by Atomic Force Microscopy. Frontiers in Cell and Developmental Biology vol. 9,
10.3389/fcell.2021.697525
Barrett DW,
Okesola BO, Costa E, Thrasivoulou C, Becker DL, Mata A, Deprest JA, David AL and
Chowdhury TT (2021).
Potential sealing and repair of human FM defects after trauma with peptide amphiphiles and Cx43 antisense. Prenatal Diagnosis vol. 41, (1) 89-99.
10.1002/pd.58262020

Read JE, Luo D,
Chowdhury TT, Flower RJ, Poston RN, Sukhorukov GB and Gould DJ (2020).
Magnetically responsive layer-by-layer microcapsules can be retained in cells and under flow conditions to promote local drug release without triggering ROS production. Nanoscale vol. 12, (14) 7735-7748.
10.1039/c9nr10329e
Dawsmith W, Ohtani N, Donnan R, Naftaly M, Dudley RA and
Chowdhury TT (2020).
Microwave Frequency Dependent Dielectric Properties of Blood as a Potential Technique to Measure Hydration. Institute of Electrical and Electronics Engineers (Ieee) Ieee Access 1-1.
10.1109/access.2020.29774322019

BARRETT DW, John RK, Thrasivoulou C, MATA A, Deprest JA, Becker DL, David AL and
CHOWDHURY TINA (2019).
Targeting mechanotransduction
mechanisms and tissue weakening
signals in the human amniotic
membrane. Nature Publishing Group Scientific Reports 10.1038/s41598-019-42379-4
Chowdhury TT, Barrett DW and David AL (2019).
Strategies to Repair Defects in the Fetal Membrane. Fetal Therapy: Scientific Basis and Critical Appraisal of Clinical Benefits 10.1017/9781108564434.0512018

Engels AC, Joyeux L, Van der Merwe J, Jimenez J, Pranpanus S, Barrett DW, Connon C,
Chowdhury TT, David AL and Deprest J (2018).
Erratum to: Tissuepatch is biocompatible and seals iatrogenic membrane defects in a rabbit model (Prenatal Diagnosis, (2018), 38, 2, (99-105), 10.1002/pd.5191). Prenatal Diagnosis vol. 38, (6)
10.1002/pd.52542017

Engels AC, Joyeux L, Van der Merwe J, Jimenez J, Prapanus S, Barrett DW, Connon C,
Chowdhury TT, David AL and Deprest J (2017).
Tissuepatch is biocompatible and seals iatrogenic membrane defects in a rabbit model. Wiley Prenatal Diagnosis vol. 38, (2) 99-105.
10.1002/pd.5191
Barrett DW, Kethees A, Thrasivoulou C, Mata A, Virasami A, Sebire NJ, Engels AC, Deprest JA, Becker DL, David AL and
Chowdhury TT (2017).
Trauma induces overexpression of Cx43 in human fetal membrane defects. Prenatal Diagnosis vol. 37, (9) 899-906.
10.1002/pd.51042016

Barrett DW, David AL, Thrasivoulou C, Mata A, Becker DL, Engels AC, Deprest JA and
Chowdhury TT (2016).
Connexin 43 is overexpressed in human fetal membrane defects after fetoscopic surgery. Prenatal Diagnosis vol. 36, (10) 942-952.
10.1002/pd.49172015

Hossain MA,
Chowdhury T and Bagul A (2015).
Imaging modalities for the in vivo surveillance of mesenchymal stromal cells. Journal of Tissue Engineering and Regenerative Medicine vol. 9, (11) 1217-1224.
10.1002/term.1907
Peake NJ, Bader DL, Vessillier S, Ramachandran M, Salter DM,
Hobbs AJ and
Chowdhury TT (2015).
C-type natriuretic peptide signalling drives homeostatic effects in human chondrocytes. Biochemical and Biophysical Research Communications vol. 465, (4) 784-789.
10.1016/j.bbrc.2015.08.087
Peake N, Pavlov A, D'Souza A, Alfasahin I, Pingaan-Murphy B, Sukhurukov G,
Hobbs A and
Chowdhury T (2015).
Polyelectrolyte microencapsules loaded with C-type natriuretic peptide protect cartilage from IL-1B induced damage. Osteoarthritis and Cartilage vol. 23, a141-a142.
10.1016/j.joca.2015.02.881
Peake NJ, Pavlov AM, D'Souza A, Pingguan-Murphy B, Sukhorukov GB,
Hobbs AJ and
CHOWDHURY TT (2015).
Controlled Release of C-Type Natriuretic Peptide by Microencapsulation Dampens Proinflammatory Effects Induced by IL-1β in Cartilage Explants. American Chemical Society Biomacromolecules 10.1021/bm501575w2014

Peake NJ,
Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F and
Chowdhury TT (2014).
Role of C-type natriuretic peptide signalling in maintaining cartilage and bone function. Osteoarthritis Cartilage vol. 22, (11) 1800-1807.
10.1016/j.joca.2014.07.018
Peake NJ, Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F and
CHOWDHURY TT (2014).
Role of C-type natriuretic peptide signaling in maintaining cartilage and bone function. Elsevier/Science Direct Osteoarthritis and Cartilage vol. online edition,
10.1016/j.joca.2014.07.018
Hossain MA,
CHOWDHURY TT and Bagul A (2014).
Imaging modalities for the in vivo surveillance of mesenchymal stromal cells. Wiley Journal of Tissue Engineering and Regenerative Medicine 10.1002/term.1907
Chowdhury B, David A, Bader D, Thrasivoulou C, Becker D and
Chowdhury T (2014).
PFM.37 Cyclic tensile strain increases PGE2 release leading to weakening of the human term amniotic membrane. Archives of Disease in Childhood - Fetal and Neonatal Edition vol. 99, (Suppl 1)
10.1136/archdischild-2014-306576.267
Parker E, Vessillier S, Abas WW, Bader DL, Pinguaan-Murphy B and
Chowdhury TT (2014).
α5β1 integrin mediates compression-induced inhibition of catabolic effects induced by fibronectin fragments in an oxygen-dependent manner. Osteoarthritis and Cartilage vol. 22,
10.1016/j.joca.2014.02.572
Chowdhury B, David AL, Thrasivoulou C, Becker DL, Bader DL and
Chowdhury TT (2014).
Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane. Placenta vol. 35, (12) 1057-1064.
10.1016/j.placenta.2014.09.0062013

Parker E, Vessillier S, Pinguaan-Murphy B, Wan Abas WAB, Bader DL and
Chowdhury TT (2013).
Low oxygen tension increased FN-f induced catabolic activities - response prevented with biomechanical signals. Biomed Central Arthritis Research and Therapy vol. 15, (5) R163-R163.
10.1186/ar4346
Akanji O, Salter DM and
Chowdhury TT (2013).
Optimisation of quantitative real-time PCR studies in cartilage mechanobiology. Pcr Technology. Current Innovations , Editors: Nolan T and Bustin SA.
Crc Pressi Llc 10.1201/b14930-25
Parker E, Pinguuan-Murphy B, Bader DL and
Chowdhury TT (2013).
FN-f induced catabolic activities are dependent on oxygen tension in chondrocyte/agarose constructs subjected to biomechanical signals. Osteoarthritis and Cartilage vol. 21,
10.1016/j.joca.2013.02.440
Hossain MA, Frampton AE,
Chowdhury TT and Morsey M (2013).
Biological vascular grafts for hemodialysis access. Informa Healthcare Expert Rev Med Devices vol. 2, (10) 171-175.
10.1586/erd.12.85
Peake N, Su N, Ramachandran M, Achan P, Salter DM, Bader DL, Moyes AJ,
Hobbs AJ and
Chowdhury TT (2013).
Natriuretic peptide receptors regulate cytoprotective effects in an ex vivo human 3D / bioreactor model. Bio Med Central Arthritis Research and Therapy vol. 15, (4)
10.1186/ar4253
Akanji O, Salter D and
Chowdhury T (2013).
Optimization of Quantitative Real-Time PCR for Studies in Cartilage Mechanobiology. Pcr Technology: Current Innovations, Third Edition 10.1201/b14930-232012
CHOWDHURY TT, Tilwani RK and Bader DL (2012).
Biomechanical conditioning enhanced matrix synthesis in nucleus pulposus cells cultured in agarase constructs with TGFβ., Editors: Goldsmith EC and Lin SK.
Journal Functional Biomaterials vol. 3, 23-26.
10.3390/jfb30100232011

Ramachandran M, Achan P, Salter DM, Bader DL and
Chowdhury TT (2011).
Biomechanical signals and the C-type natriuretic peptide counteract catabolic activities induced by IL-1β in chondrocyte/agarose constructs. Arthritis Research and Therapy vol. 13, (5)
10.1186/ar3459
Bader DL, Salter DM and
Chowdhury TT (2011).
Biomechanical influence of cartilage homeostasis in health and disease. Arthritis vol. 2011,
10.1155/2011/979032
Lee DA, Brand J, Salter D, Akanji O-O and
Chowdhury TT (2011).
Quantification of mRNA using real-time PCR and Western blot analysis of MAPK events in chondrocyte/agarose constructs. Methods Mol Biol vol. 695, 77-97.
10.1007/978-1-60761-984-0_62010
Chowdhury TT, Schulz RM, Rai SS, Thuemmler CB, Wuestneck N, Bader A and Homandberg GA (2010).
Biomechanical modulation of collagen fragment-induced anabolic and catabolic activities in chondrocyte/agarose constructs. Arthritis Research and Therapy vol. 12, (3)
10.1186/ar3009
McGlashan SR,
Knight MM,
Chowdhury TT, Joshi P, Jensen CG, Kennedy S and Poole CA (2010).
Mechanical loading modulates chondrocyte primary cilia incidence and length. Cell Biology International vol. 34, (5) 441-446.
10.1042/CBI20090094
Akanji OO, Sakthithasan P, Salter DM and
Chowdhury TT (2010).
Dynamic compression alters NFκB activation and IκB-α expression in IL-1β-stimulated chondrocyte/agarose constructs. Inflammation Research vol. 59, (1) 41-52.
10.1007/s00011-009-0068-92009

Akanji OO, Salter DM and
Chowdhury TT (2009).
458 DYNAMIC COMPRESSION ALTERS NF?B ACTIVATION AND I?B-α EXPRESSION IN IL-1β STIMULATED CHONDROCYTE/AGAROSE CONSTRUCTS. Osteoarthritis and Cartilage vol. 17, s245-s246.
10.1016/s1063-4584(09)60479-9
Raveenthiran SP and
Chowdhury TT (2009).
Dynamic compression inhibits fibronectin fragment induced iNOS and COX-2 expression in chondrocyte/agarose constructs. Biomechanics and Modeling in Mechanobiology vol. 8, (4) 273-283.
10.1007/s10237-008-0134-12008

Raveenthiran SP and
Chowdhury TT (2008).
451 DYNAMIC COMPRESSION COUNTERACTS FIBRONECTIN-FRAGMENT INDUCED INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS. Osteoarthritis and Cartilage vol. 16, s195-s196.
10.1016/s1063-4584(08)60492-6
Chowdhury TT, Salter DM, Bader DL and
Lee DA (2008).
Signal transduction pathways involving p38 MAPK, JNK, NF kappa B and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1 beta and dynamic compression. Inflamm Res vol. 57, (7) 306-313.
10.1007/s00011-007-7126-y
CHOWDHURY TT, Akanjii OO, Salter DM and Lee DA (2008).
Dynamic compression influences IL-1β induced NO and PGE2 release, via alterations in iNOS and COX-2 activity. 5th International Symposium On Mechanobiology of Cartilage and Chondrocyte , Editors: Stoltz JF.
Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Bader DL, Salter DM and
Lee DA (2008).
Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs. Arthritis Res Ther vol. 10, (2)
10.1186/ar2389
Chowdhury TT, Akanji OO, Salter DM, Bader DL and
Lee DA (2008).
Dynamic compression influences interleukin-1 beta-induced nitric oxide and prostaglandin E-2 release by articular chondrocytes via alterations in iNOS and COX-2 expression. Biorheology vol. 45, (3-4) 257-274.
10.3233/BIR-2008-04742007
Chowdhury TT, Akanji OO, Arghandawi S, Salter DM, Bader DL and
Lee DA (2007).
52 REAL-TIME PCR USING MOLECULAR BEACONS TO DETECT INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS SUBJECTED TO IL-1β AND DYNAMIC COMPRESSION. Osteoarthritis and Cartilage vol. 15, c42-c43.
10.1016/s1063-4584(07)61688-4
Campbell JJ, Blain EJ,
Chowdhury TT and
Knight MM (2007).
Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes. Biochemical and Biophysical Research Communications vol. 361, (2) 329-334.
10.1016/j.bbrc.2007.06.1852006
Chowdhury TT and
Knight MM (2006).
Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression. Journal of Cellular Physiology vol. 209, (3) 845-853.
10.1002/jcp.20768
Chowdhury TT, Appleby RN, Salter DM, Bader DA and
Lee DA (2006).
Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes. Biomech Model Mechanobiol vol. 5, (2-3) 192-201.
10.1007/s10237-006-0032-3
CHOWDHURY TT, Bader DL and Lee DA (2006).
Dynamic compression counteracts IL-1β induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Mechanobiology: Cartilage and Chondrocyte , Editors: Stoltz JF.
Ios Press
Chowdhury TT, Bader DL and
Lee DA (2006).
Dynamic compression counteracts IL-1beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Biorheology vol. 43, (3,4) 413-429.
2005
Chowdhury TT, Bader DL and
Lee DA (2005).
Dynamic compression counteracts IL-1-induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 251-252.
Chowdhury TT, Appleby RN, Salter DA, Bader DL and
Lee DA (2005).
Integrin mediated mechanotransduction in IL-1 stimulated bovine chondrocytes cultured in agarose constructs. Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 545-546.
Chowdhury TT, Bader DL and
Lee DA (2005).
Dynamic compression counteracts IL-1β induced INOS and COX-2 activity by human chondrocytes cultured in agarose constructs. European Cells and Materials vol. 10, (SUPPL.2)

Catuogno C,
Chowdhury TT, Bader DL and
Lee DA (2005).
Dynamic compression influences the biochemical response of human mesenchymal stem cells cultured in agarose constructs. European Cells and Materials vol. 10, (SUPPL.2)

Sudre L, Cheung F, Kevorkian L, Young DA, Darrah C, Donell ST, Shepstone L, Porter S, Brockbank S, Edwards DR, Parker AE, Clark IM, Boubriak OA, Urban JPG, Cui Z, Tew SR, Li Y, Tweats LM, Hawkins RE, Hardingham TE, Green D, Partridge KA, Leveque I, Mann S, Oreffo ROC, Ball SG, Kielty CM, Qin M, Tai G and Polak JM (2005).
British society for matrix biology autumn meeting. International Journal of Experimental Pathology vol. 86, (3)
10.1111/j.0959-9673.2005.00426.x2004
Chowdhury TT, Salter DM, Bader DL and
Lee DA (2004).
Integrin-mediated mechanotransduction processes in TGFbeta-stimulated monolayer-expanded chondrocytes. Biochem Biophys Res Commun vol. 318, (4) 873-881.
10.1016/j.bbrc.2004.04.107
Bryant SJ,
Chowdhury TT,
Lee DA, Bader DL and Anseth KS (2004).
Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels. Ann Biomed Eng vol. 32, (3) 407-417.
10.1023/b:abme.0000017535.00602.ca2003
Chowdhury TT, Bader DL and
Lee DA (2003).
Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE2 by superficial zone chondrocytes cultured in agarose constructs. Osteoarthritis Cartilage vol. 11, (9) 688-696.
10.1016/s1063-4584(03)00149-3
Chowdhury TT,
Shelton JC, Bader DL and
LEE DA (2003).
Control of mechanotrasduction processes in dynamically stimulated human and bovine chondrocytes cultured in agarose constructs. Internat. J. Artificial Organs vol. 26, (9) 858-858.
Chowdhury TT,
LEE DA, Salter DM,
Shelton JC and Bader DL (2003).
alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta-stimulated human chondrocyte / agarose constructs and subjected to dynamic compression. Osteoarthritis Cartilage vol. 11, (Suppl 1) S2-S3.
2001
Chowdhury TT, Bader DL and
Lee DA (2001).
Dynamic compression inhibits the synthesis of nitric oxide and PGE(2) by IL-1beta-stimulated chondrocytes cultured in agarose constructs. Biochem Biophys Res Commun vol. 285, (5) 1168-1174.
10.1006/bbrc.2001.53112000
Chowdhury TT, Bader DL and
Lee DA (2000).
Dynamic compression inhibits the synthesis of nitric oxide by IL-1β stimulated chondrocytes cultured in agarose constructs. Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell