Dr Nidal Khatib

Nidal Khatib

Research Fellow

Queen Mary University of London
ORCID Google Scholar LinkedIn

Research

Microphysiological systems, Tendon, Mechanobiology, Organ-chip

Musculoskeletal Models

Interests

My main area of expertise is in musculoskeletal physiology and disease, with a focus on mechanobiology, disease pathology and biomechanics.

My previous research has focussed on the importance of biophysical cues in embryonic skeletal development and in the progression of skeletal conditions such as osteoarthritis.

In my current role at QMUL, I am contributing to the Screen research group interest of developing physiologically-relevant in vitro models of tendon and tendinopathy. This includes development of a human vascularised tendon-on-a-chip model, and elucidating mechanobiological and inflammatory disease pathways.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2025

Maternal exercise rescues fetal akinesia-impaired joint and bone development
Panebianco C, Huang Y, Khatib N, Gottlieb D, Essaidi M, Ahmed S, Dyment N, Simmons R et al.
Biorxiv 
17-06-2025

2023

Continuous non-invasive measurement of cardiac output in neonatal intensive care using regional impedance cardiography: a prospective observational study
Banerjee J, Khatib N, Mansfield RC, Sathiyamurthy S, Kariholu U, Lees C
Archives of Disease in Childhood Fetal & Neonatal, Bmj vol. 109 (4), 450-455.  
14-12-2023
Mechanoregulatory role of TRPV4 in prenatal skeletal development
Khatib NS, Monsen J, Ahmed S, Huang Y, Hoey DA, Nowlan NC
Science Advances, American Association For The Advancement of Science (Aaas) vol. 9 (4) 
25-01-2023

2021

Differential effect of frequency and duration of mechanical loading on fetal chick cartilage and bone development
Khatib N, Department of Bioengineering ICL, Parisi C, Nowlan N
Ecells & Materials, European Cells and Materials vol. 41, 531-545.  
25-05-2021

2019

Comparison of gait, functional activities, and patient-reported outcome measures in patients with knee osteoarthritis and healthy adults using 3D motion analysis and activity monitoring: an exploratory case-control analysis
Sparkes V, Whatling GM, Biggs P, Khatib N, Al-Amri M, Williams D, Hemming R, Hagen M et al.
Orthopedic Research and Reviews, Taylor & Francis vol. 11, 129-140.  
01-09-2019
Dynamic medial knee overloading influences inflammation and bone remodelling in the degenerative knee
Khatib N, Biggs P, Wilson C, Williams R, Mason D, Holt C
Osteoarthritis and Cartilage. 
01-04-2019

2018

Subjects with medial and lateral tibiofemoral articular cartilage defects do not alter compartmental loading during walking
Van Rossom S, Khatib N, Holt C, Van Assche D, Jonkers I
Clinical Biomechanics, Elsevier vol. 60, 149-156.  
13-10-2018
Identifying load responsive synovial fluid metabolic markers following pivot-shift testing in ACL injury subjects
Khatib N, Andreas P, Fairhurst S, Wilson C, Mason D
Osteoarthritis and Cartilage. 
01-04-2018

2016

Developing an in vitro model of healthy and osteoarthritic medial knee compartmental loading
Khatib N, Metcalf A, Blain E, Mason D, Holt C
Osteoarthritis and Cartilage. 
01-04-2016