Publications
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Publications of specific relevance to Predictive in vitro Models
2023
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Bhattacharya P, Dhawan UK, Hussain MT, Singh P, Bhagat KK, Singhal A, Austin-Williams S, Sengupta S and
Subramanian M (2023).
Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling. Elsevier Cell Reports vol. 42, (7)
10.1016/j.celrep.2023.1128082022
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Dhawan UK, Margraf A, Lech M and
Subramanian M (2022).
Hypercholesterolemia promotes autoantibody production and a lupus‐like pathology via decreased DNase‐mediated clearance of DNA. Wiley Journal of Cellular and Molecular Medicine vol. 26, (20) 5267-5276.
10.1111/jcmm.17556![](/publications/bullet24.png)
Bhattacharya P, Kanagasooriyan R and
Subramanian M (2022).
Tackling inflammation in atherosclerosis: Are we there yet and what lies beyond? Elsevier Current Opinion in Pharmacology vol. 66,
10.1016/j.coph.2022.102283![](/publications/bullet24.png)
Manickam V, Dhawan UK, Singh D, Gupta M and
Subramanian M (2022).
Pomegranate Peel Extract Decreases Plaque Necrosis and Advanced Atherosclerosis Progression in Apoe -/- Mice. Frontiers Frontiers in Pharmacology vol. 13,
10.3389/fphar.2022.8883002021
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Dhawan UK, Bhattacharya P, Narayanan S, Manickam V, Aggarwal A and
Subramanian M (2021).
Hypercholesterolemia Impairs Clearance of Neutrophil Extracellular Traps and Promotes Inflammation and Atherosclerotic Plaque Progression. American Heart Association Arteriosclerosis, Thrombosis and Vascular Biology ATVBAHA1203-ATVBAHA1203.
10.1161/ATVBAHA.120.316389![](/publications/bullet24.png)
Dhawan UK, Singhal A and
Subramanian M (2021).
Dead cell and debris clearance in the atherosclerotic plaque: Mechanisms and therapeutic opportunities to promote inflammation resolution. Elsevier Pharmacological Research vol. 170,
10.1016/j.phrs.2021.105699![](/publications/bullet24.png)
Naushin S, Sardana V, Ujjainiya R, Bhatheja N, Kutum R, Bhaskar AK, Pradhan S, Prakash S, Khan R, Rawat BS, Tallapaka KB, Anumalla M, Chandak GR, Lahiri A, Kar S, Mulay SR, Mugale MN, Srivastava M, Khan S, Srivastava A, Tomar B, Veerapandian M, Venkatachalam G, Vijayakumar SR, Agarwal A, Gupta D, Halami PM, Peddha MS, Sundaram GM and Veeranna RP (2021).
Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2. Elife Elife vol. 10,
10.7554/elife.66537![](/publications/bullet24.png)
DeBerge M, Glinton K,
Subramanian M, Wilsbacher LD, Rothlin CV, Tabas I and Thorp EB (2021).
Macrophage AXL receptor tyrosine kinase inflames the heart after reperfused myocardial infarction. American Society For Clinical Investigation Journal of Clinical Investigation vol. 131, (6)
10.1172/jci1395762020
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Yurdagul A,
Subramanian M, Wang X, Crown SB, Ilkayeva OR, Darville L, Kolluru GK, Rymond CC, Gerlach BD, Zheng Z, Kuriakose G, Kevil CG, Koomen JM, Cleveland JL, Muoio DM and Tabas I (2020).
Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury. Elsevier Cell Metabolism vol. 31, (3) 518-533.e10.
10.1016/j.cmet.2020.01.0012018
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Proto JD, Doran AC, Gusarova G, Yurdagul A, Sozen E,
Subramanian M, Islam MN, Rymond CC, Du J, Hook J, Kuriakose G, Bhattacharya J and Tabas I (2018).
Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution. Elsevier Immunity vol. 49, (4) 666-677.e6.
10.1016/j.immuni.2018.07.015![](/publications/bullet24.png)
Proto JD, Doran AC,
Subramanian M, Wang H, Zhang M, Sozen E, Rymond CC, Kuriakose G, D'Agati V, Winchester R, Sykes M, Yang Y-G and Tabas I (2018).
Hypercholesterolemia induces T cell expansion in humanized immune mice. American Society For Clinical Investigation Journal of Clinical Investigation vol. 128, (6) 2370-2375.
10.1172/jci977852017
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Wang Y,
Subramanian M, Yurdagul A, Barbosa-Lorenzi VC, Cai B, de Juan-Sanz J, Ryan TA, Nomura M, Maxfield FR and Tabas I (2017).
Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages. Elsevier Cell vol. 171, (2) 331-345.e22.
10.1016/j.cell.2017.08.0412016
Subramanian M, Proto JD, Matsushima GK and Tabas I (2016).
Deficiency of AXL in Bone Marrow-Derived Cells Does Not Affect Advanced Atherosclerotic Lesion Progression. Springer Nature Scientific Reports vol. 6, (1)
10.1038/srep39111![](/publications/bullet24.png)
Cai B, Thorp EB, Doran AC,
Subramanian M, Sansbury BE, Lin C-S, Spite M, Fredman G and Tabas I (2016).
MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation. Proceedings of The National Academy of Sciences Proceedings of The National Academy of Sciences of The United States of America vol. 113, (23) 6526-6531.
10.1073/pnas.1524292113![](/publications/bullet24.png)
Kamaly N, Fredman G, Fojas JJR,
Subramanian M, Choi WI, Zepeda K, Vilos C, Yu M, Gadde S, Wu J, Milton J, Leitao RC, Fernandes LR, Hasan M, Gao H, Nguyen V, Harris J, Tabas I and Farokhzad OC (2016).
Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis. American Chemical Society (Acs) Acs Nano vol. 10, (5) 5280-5292.
10.1021/acsnano.6b011142015
Subramanian M, Ozcan L, Ghorpade DS, Ferrante AW and Tabas I (2015).
Suppression of Adaptive Immune Cell Activation Does Not Alter Innate Immune Adipose Inflammation or Insulin Resistance in Obesity. Public Library of Science (Plos) Plos One vol. 10, (8)
10.1371/journal.pone.0135842![](/publications/bullet24.png)
Proto J,
Subramanian M, Islam M, Hook J, Gusarova G, Bhattacharya J and Tabas I (2015).
A Potential Role for Regulatory T Cells in Apoptotic Cell Clearance by Macrophages in a Murine Model of Acute Lung Injury. Wiley The Faseb Journal vol. 29, (S1)
10.1096/fasebj.29.1_supplement.148.3
Subramanian M, Thorp E and Tabas I (2015).
Identification of a non-growth factor role for GM-CSF in advanced atherosclerosis: promotion of macrophage apoptosis and plaque necrosis through IL-23 signaling. Circ Res vol. 116, (2) e13-e24.
10.1161/CIRCRESAHA.116.304794![](/publications/bullet24.png)
Ash D,
Subramanian M, Surolia A and Shaha C (2015).
Nitric oxide is the key mediator of death induced by fisetin in human acute monocytic leukemia cells. American Journal of Cancer Research vol. 5, (2) 481-497.
2014
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Wang M,
Subramanian M, Abramowicz S, Murphy AJ, Gonen A, Witztum J, Welch C, Tabas I, Westerterp M and Tall AR (2014).
Interleukin-3/Granulocyte Macrophage Colony–Stimulating Factor Receptor Promotes Stem Cell Expansion, Monocytosis, and Atheroma Macrophage Burden in Mice With Hematopoietic ApoE Deficiency. Wolters Kluwer Arteriosclerosis Thrombosis and Vascular Biology vol. 34, (5) 976-984.
10.1161/atvbaha.113.303097
Subramanian M and Tabas I (2014).
A new RIDDle in DC-mediated cross-presentation. Springer Nature Nature Immunology vol. 15, (3) 213-215.
10.1038/ni.2826
Subramanian M, Hayes CD, Thome JJ, Thorp E, Matsushima GK, Herz J, Farber DL, Liu K, Lakshmana M and Tabas I (2014).
An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo. American Society For Clinical Investigation Journal of Clinical Investigation vol. 124, (3) 1296-1308.
10.1172/jci72051![](/publications/bullet24.png)
Westphalen K, Gusarova GA, Islam MN,
Subramanian M, Cohen TS, Prince AS and Bhattacharya J (2014).
Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity. Springer Nature Nature vol. 506, (7489) 503-506.
10.1038/nature129022013
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Kamaly N, Fredman G,
Subramanian M, Gadde S, Pesic A, Cheung L, Fayad ZA, Langer R, Tabas I and Farokhzad OC (2013).
Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles. Proceedings of The National Academy of Sciences Proceedings of The National Academy of Sciences of The United States of America vol. 110, (16) 6506-6511.
10.1073/pnas.13033771102012
Subramanian M, Thorp E, Hansson GK and Tabas I (2012).
Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs. American Society For Clinical Investigation Journal of Clinical Investigation vol. 123, (1) 179-188.
10.1172/jci64617![](/publications/bullet24.png)
Liao X, Sluimer JC, Wang Y,
Subramanian M, Brown K, Pattison JS, Robbins J, Martinez J and Tabas I (2012).
Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis. Elsevier Cell Metabolism vol. 15, (4) 545-553.
10.1016/j.cmet.2012.01.0222011
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Thorp E,
Subramanian M and Tabas I (2011).
The role of macrophages and dendritic cells in the clearance of apoptotic cells in advanced atherosclerosis. Wiley European Journal of Immunology vol. 41, (9) 2515-2518.
10.1002/eji.201141719![](/publications/bullet24.png)
Thorp E, Vaisar T,
Subramanian M, Mautner L, Blobel C and Tabas I (2011).
Shedding of the Mer Tyrosine Kinase Receptor Is Mediated by ADAM17 Protein through a Pathway Involving Reactive Oxygen Species, Protein Kinase Cδ, and p38 Mitogen-activated Protein Kinase (MAPK). Elsevier Journal of Biological Chemistry vol. 286, (38) 33335-33344.
10.1074/jbc.m111.2630202009
Subramanian M and Shaha C (2009).
Oestrogen modulates human macrophage apoptosis via differential signalling through oestrogen receptor‐α and β. Wiley Journal of Cellular and Molecular Medicine vol. 13, (8b) 2317-2329.
10.1111/j.1582-4934.2008.00679.x
Subramanian M and Shaha C (2009).
Oestrogen modulates human macrophage apoptosis via differential signalling through oestrogen receptor-α and β. Journal of Cellular and Molecular Medicine vol. 13, (8B) 2317-2329.
10.1111/j.1582-4934.2009.00679.x2007
Subramanian M and Shaha C (2007).
Up-Regulation of Bcl-2 through ERK Phosphorylation Is Associated with Human Macrophage Survival in an Estrogen Microenvironment. The American Association of Immunologists The Journal of Immunology vol. 179, (4) 2330-2338.
10.4049/jimmunol.179.4.2330