Dr Isabel M Palacios
Lecturer
School of Biological and Behavioural Sciences
Queen Mary University of London
Queen Mary University of London
Research
tissue architecture, cytoskeletons, human stem cells, drosophila, organoids, cerebral organoids, healthy and diseased, neurodegeneration
Interests
Techniques: Drosophila, 2D and 3D cell culture models and human organoids.Reserach:
1. Tissue Biomechanics in the Whole Organism. Our research group focuses on understanding the genetic and cell biophysics of cell and tissue organisation in a multicellular organism, using Drosophila melanogaster as a model system. These are basic cellular processes that are conserved in the development of all organisms, and that contribute to diseases when mis-regulated.
2. Tissue biomechanics in 3D Human Cerebral Organoids. Limited knowledge exists regarding how morphogenesis and tissue architecture may contribute to the development of our brain. Combining bioengineering, cell biophysics and functional genetics we are studying the biophysical principles governing neuro-epithelia formation, the early brain development stage.
Experimental biophysicists and biologists are welcome to join us. https://palacioslabqmul.squarespace.com/research
Isa is also a co-founder of the DrosAfrica charity (https://drosafrica.org), building a connected African biomedical research community using Drosophila as a model system.
Publications
2024

Palacios IM, Palacios De Castro MI
Biorxiv Journal
24-04-2024
2023

López EM, Kabanova A, Winkel A, Franze K, Palacios IM, Martín-Bermudo MD
Plos Biology, Public Library of Science vol. 21 (6)
28-06-2023
2020

Palacios I, Vicente-Crespo M, Martín-Bermudo MD
Nature Reviews Molecular Cell Biology, Springer Nature vol. 21 (10), 558-559.
17-08-2020

Santa-Cruz Mateos C, Valencia-Expósito A, Palacios IM, Martín-Bermudo MD
Plos Genetics, Public Library of Science (Plos) vol. 16 (6), e1008717-e1008717.
01-06-2020

Drechsler M, Lang LF, Al-Khatib L, Dirks H, Burger M, Schönlieb C-B, Palacios IM
Molecular Biology of The Cell, American Society For Cell Biology, mbcE1908044-mbcE1908044.
08-04-2020
2019

Francis D, Chanana B, Fernandez B, Gordon B, Mak T, Palacios IM
Plos One, Public Library of Science (Plos) vol. 14 (4)
03-04-2019
2017

PALACIOS IM
Nature Communications, Nature Publishing Group vol. 8
15-11-2017

Martín-Bermudo MD, Gebel L, Palacios IM
Seminars in Cell & Developmental Biology, Elsevier Bv vol. 70, 58-64.
30-08-2017
2016

Ng BF, Selvaraj GK, Santa-Cruz Mateos C, Grosheva I, Alvarez-Garcia I, Martín-Bermudo MD, Palacios IM
Journal of Cell Science, The Company of Biologists vol. 129 (9), e1.2-e1.2.
01-05-2016

Vicente‐Crespo M, Muñoz‐Descalzo S, Weil T, Martín‐Bermudo MD, Palacios I
01-04-2016

Ng BF, Selvaraj GK, Santa-Cruz Mateos C, Grosheva I, Alvarez-Garcia I, Martín-Bermudo MD, Palacios IM
Development, The Company of Biologists vol. 143 (8), 1388-1399.
07-03-2016

Saavedra P, Brittle A, Palacios IM, Strutt D, Casal J, Lawrence PA
Biology Open, The Company of Biologists vol. 5 (4), 397-408.
02-03-2016
2015

Palacios IM, Drechsler M, Ganguly S
01-01-2015

Palacios IM, Martin-Bermudo M
01-01-2015

Palacios IM, Drechsler M, Ganguly S
01-01-2015
2014

Palacios IM
Journal of Cell Biology, Rockefeller University Press vol. 204 (3), 287-289.
03-02-2014

Saavedra P, Vincent J-P, Palacios IM, Lawrence PA, Casal J
Elife, Elife vol. 3
01-01-2014

Gómez-Lamarca MJ, Cobreros-Reguera L, Ibáñez-Jiménez B, Palacios IM, Martín-Bermudo MD
Journal of Cell Science, The Company of Biologists vol. 127 (21), 4667-4678.
01-01-2014

Braun AL, Chanana B, Palacios IM
01-01-2014

Drechsler M, Goldstein R, Palacios IM
01-01-2014

Williams LS, Ganguly S, Loiseau P, Ng BF, Palacios IM
Journal of Cell Science, The Company of Biologists vol. 127 (1), e1-e1.
01-01-2014
2013

Roca-Varela ML, Palacios IM
International Journal of English Studies, Servicio De Publicaciones De La Universidad De Murcia vol. 13 (2), 53-68.
01-12-2013

Williams LS, Ganguly S, Loiseau P, Ng BF, Palacios IM
Development, The Company of Biologists vol. 141 (1), 176-186.
20-11-2013
2012

Palacios IM
Briefings in Functional Genomics, Oxford University Press (Oup) vol. 12 (1), 25-36.
11-11-2012

Ganguly S, Williams LS, Palacios IM, Goldstein RE
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 109 (38), 15109-15114.
04-09-2012

Baden T, Palacios I, Vicente M, Martin Bermudo MD, Yusuf S, Godino LP
01-01-2012
2011

Avery P, Vicente-Crespo M, Francis D, Nashchekina O, Alonso CR, Palacios IM
Rna, Cold Spring Harbor Laboratory vol. 17 (4), 624-638.
11-02-2011

Vicente-Crespo M, Palacios IM
Biochemical Society Transactions, Portland Press vol. 39 (1), 411-411.
19-01-2011
2010

Vicente-Crespo M, Palacios IM
Biochemical Society Transactions, Portland Press vol. 38 (6), 1500-1505.
24-11-2010

Loiseau P, Davies T, Williams LS, Mishima M, Palacios IM
Journal of Cell Science, The Company of Biologists vol. 123 (16), e1-e1.
15-08-2010

Loiseau P, Davies T, Williams LS, Mishima M, Palacios IM
Development, The Company of Biologists vol. 137 (16), 2763-2772.
14-07-2010
2007

Meignin C, Alvarez-Garcia I, Davis I, Palacios IM
Current Biology, Elsevier vol. 17 (21), 1871-1878.
25-10-2007

Palacios IM
Seminars in Cell and Developmental Biology, Elsevier vol. 18 (2), 163-170.
26-01-2007
2004

Palacios IM, Gatfield D, St Johnston D, Izaurralde E
Nature, Springer Nature vol. 427 (6976), 753-757.
01-02-2004
2003

Macchi P, Kroening S, Palacios IM, Baldassa S, Grunewald B, Ambrosino C, Goetze B, Lupas A et al.
Journal of Neuroscience, Society For Neuroscience vol. 23 (13), 5778-5788.
02-07-2003
2002

Palacios IM, St Johnston D
Development, The Company of Biologists vol. 129 (23), 5473-5485.
01-12-2002

Benton R, Palacios IM, St Johnston D
Developmental Cell, Elsevier vol. 3 (5), 659-671.
01-11-2002

Palacios IM
Current Biology, Elsevier vol. 12 (2), r50-r52.
01-01-2002
2001

Palacios IM, Johnston DS
Annual Review of Cell and Developmental Biology, Annual Reviews vol. 17 (1), 569-614.
01-11-2001

Wagner C, Palacios I, Jaeger L, St Johnston D, Ehresmann B, Ehresmann C, Brunel C
Journal of Molecular Biology, Elsevier vol. 313 (3), 511-524.
01-10-2001

van Eeden FJM, Palacios IM, Petronczki M, Weston MJD, St Johnston D
Journal of Cell Biology, Rockefeller University Press vol. 154 (3), 511-524.
30-07-2001

Palacios I, Izaurralde E
In Encyclopedia of Life Sciences, Wiley
19-04-2001
1997

Palacios I, Hetzer M, Adam SA, Mattaj IW
The Embo Journal, Springer Nature vol. 16 (22), 6783-6792.
15-11-1997

Palacios I, Izaurralde E
01-02-1997

Dingwall C, Palacios I
Methods in Cell Biology, Elsevier vol. 53, 517-543.
01-01-1997
1996

Palacios I, Weis K, Klebe C, Mattaj IW, Dingwall C
Journal of Cell Biology, Rockefeller University Press vol. 133 (3), 485-494.
01-05-1996

Perales B, de la Luna S, Palacios I, Ortín J
Journal of Virology, American Society For Microbiology vol. 70 (3), 1678-1686.
01-03-1996
1995

Boelens WC, Palacios I, Mattaj IW
Rna vol. 1 (3), 273-283.
01-05-1995
Grants


Viji Draviam Sastry, Caroline Brennan, Vidya Darbari, Jose Martin Duran, Ivan Kadurin, Isabel M Palacios, Richard Pickersgill, Sarah McClelland, Tyson Sharp and Martin Knight
£386,205 MRC Medical Research Council
01-10-2022 - 31-03-2023

Conrad Mullineaux, Caroline Brennan, Alexandre De Mendoza Soler, Viji Draviam Sastry, Maurice Elphick, Christoph Engl, Isabel M Palacios, Matteo Palma, Marina Resmini, Alexander Ruban, Peter Thorpe, Angelika Stollewerk, Jose Martin Duran, Paulo Baptista Ribeiro, Susana Godinho, Richard Grose, Stephanie Kermorgant, Peter McCormick and Tyson Sharp
£390,834 BBSRC Biotechnology and Biological Sciences Research Council
01-08-2022 - 31-07-2023