Dr GIANMICHELE MASSIMO
QUEEN MARY UNIVERSITY OF LONDONg.email@example.com
InterestsMy research activity aims to understand how genetic mutations of the xanthine oxidase enzyme affect its activity. To do that, I developed a stable cell line of hXDH-HEK-293. Since my first steps in science, I have been using primary and secondary cell lines for my research activity. Now I am more in than phase where I want to learn how to develop a 3-D cell model and understand what sort of advantages I could get from this approach for my current and future project.
Kapil V, Khambata RS, Jones DA, Rathod K, Primus C, Massimo G, Fukuto JM and Ahluwalia A (2020). The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway. Pharmacological Reviews vol. 72, (3) 692-766. 10.1124/pr.120.019240