Dr Christopher Chapman

Christopher Chapman

Lecturer in Bioengineering

Queen Mary University of London

Research

bioelectronics, biosensing, medical devices, conducting polymers

Interests

Interested in pairing bioelectronic sensors to in vitro models to achieve real-time readout from the in vitro model system. Investigating coupling multiple modalities of recordings such as impedance, pH, and biomarker sensing to the in vitro systems.

Publications

Publications of specific relevance to Predictive in vitro Models

2023

Chapman CAR, Fernandez-Patel S, Jahan N, Cuttaz EA, Novikov A, Goding JA and Green RA (2023). Controlled electroactive release from solid-state conductive elastomer electrodes. Elsevier  Materials Today Bio  vol. 23, 10.1016/j.mtbio.2023.100883
Alkahtani ME, Elbadawi M, Chapman CAR, Green RA, Gaisford S, Orlu M and Basit AW (2023). Electroactive Polymers for On‐Demand Drug Release. Wiley  Advanced Healthcare Materials  vol. 13, (3) 10.1002/adhm.202301759
Steenbergen N, Busha I, Morgan A, Mattathil C, Pinto AL, Spyridakos F, Sokolovskiy I, Tahirbegi B, Chapman C, Cuttaz E, Litvinova K, Goding J and Green R (2023). Surface electromyography using dry polymeric electrodes. Aip Publishing  Apl Bioengineering  vol. 7, (3) 10.1063/5.0148101

2022

Rapeaux A, Syed O, Cuttaz E, Chapman CAR, Green RA and Constandinou TG (2022). Preparation of Rat Sciatic Nerve for Ex Vivo Neurophysiology. Myjove Corporation  Journal of Visualized Experiments  (185) 10.3791/63838
Rapeaux A, Syed O, Cuttaz E, Chapman CAR, Green RA and Constandinou TG (2022). Preparation of Rat Sciatic Nerve for Ex Vivo Neurophysiology. Myjove Corporation  Journal of Visualized Experiments  (185) 10.3791/63838-v

2021

Chapman CAR, Cuttaz EA, Tahirbegi B, Novikov A, Petkos K, Koutsoftidis S, Drakakis EM, Goding JA and Green RA (2021). Flexible Networks of Patterned Conducting Polymer Nanowires for Fully Polymeric Bioelectronics. Wiley  Advanced Nanobiomed Research  vol. 2, (3) 10.1002/anbr.202100102
Portillo-Lara R, Tahirbegi B, Chapman CAR, Goding JA and Green RA (2021). Mind the gap: State-of-the-art technologies and applications for EEG-based brain–computer interfaces. Aip Publishing  Apl Bioengineering  vol. 5, (3) 10.1063/5.0047237
Cuttaz EA, Chapman CAR, Syed O, Goding JA and Green RA (2021). Stretchable, Fully Polymeric Electrode Arrays for Peripheral Nerve Stimulation. Wiley  Advanced Science  vol. 8, (8) 10.1002/advs.202004033
Aristovich K, Donega M, Fjordbakk C, Tarotin I, Chapman CAR, Viscasillas J, Stathopoulou T-R, Crawford A, Chew D, Perkins J and Holder D (2021). Model-based geometrical optimisation and in vivo validation of a spatially selective multielectrode cuff array for vagus nerve neuromodulation. Elsevier  Journal of Neuroscience Methods  vol. 352, 10.1016/j.jneumeth.2021.109079

2020

Novikov A, Goding J, Chapman C, Cuttaz E and Green RA (2020). Stretchable bioelectronics: Mitigating the challenges of the percolation threshold in conductive elastomers. Aip Publishing  Apl Materials  vol. 8, (10) 10.1063/5.0005410
Chapman CAR, Cuttaz EA, Goding JA and Green RA (2020). Actively controlled local drug delivery using conductive polymer-based devices. Aip Publishing  Applied Physics Letters  vol. 116, (1) 10.1063/1.5138587
Syed O, Chapman C, Vallejo-Giraldo C, Genta M, Goding J, Kanelos E and Green R (2020). 3D Cell Culture Systems for the Development of Neural Interfaces. Neural Interface Engineering  Springer Nature  10.1007/978-3-030-41854-0_8

2019

Chapman CAR, Smith TM, Kelly M, Avery J, Rouanet T, Aristovich K, Chew DJ and Holder DS (2019). Optimisation of bioimpedance measurements of neuronal activity with an ex vivo preparation of Cancer pagurus peripheral nerves. Elsevier  Journal of Neuroscience Methods  vol. 327, 10.1016/j.jneumeth.2019.108322
Hope J, Aristovich K, Chapman CAR, Volschenk A, Vanholsbeeck F and McDaid A (2019). Extracting impedance changes from a frequency multiplexed signal during neural activity in sciatic nerve of rat: preliminary study in vitro. Iop Publishing  Physiological Measurement  vol. 40, (3) 10.1088/1361-6579/ab0c24

2018

Chapman CAR, Aristovich K, Donega M, Fjordbakk CT, Stathopoulou T-R, Viscasillas J, Avery J, Perkins JD and Holder D (2018). Electrode fabrication and interface optimization for imaging of evoked peripheral nervous system activity with electrical impedance tomography (EIT). Iop Publishing  Journal of Neural Engineering  vol. 16, (1) 10.1088/1741-2552/aae868

2017

Chapman CAR, Goshi N and Seker E (2017). Multifunctional Neural Interfaces for Closed‐Loop Control of Neural Activity. Wiley  Advanced Functional Materials  vol. 28, (12) 10.1002/adfm.201703523
Chapman CAR, Zhu X, Chen H, Yanik AA, Lein PJ and Seker E (2017). Nanostructure Introduces Artifacts in Quantitative Immunofluorescence by Influencing Fluorophore Intensity. Springer Nature  Scientific Reports  vol. 7, (1) 10.1038/s41598-017-00447-7
Chapman CAR, Wang L, Chen H, Garrison J, Lein PJ and Seker E (2017). Neural Interfaces: Nanoporous Gold Biointerfaces: Modifying Nanostructure to Control Neural Cell Coverage and Enhance Electrophysiological Recording Performance (Adv. Funct. Mater. 3/2017). Wiley  Advanced Functional Materials  vol. 27, (3) 10.1002/adfm.201770015

2016

Chapman CAR, Wang L, Chen H, Garrison J, Lein PJ and Seker E (2016). Nanoporous Gold Biointerfaces: Modifying Nanostructure to Control Neural Cell Coverage and Enhance Electrophysiological Recording Performance. Wiley  Advanced Functional Materials  vol. 27, (3) 10.1002/adfm.201604631
Chapman CAR, Chen H, Stamou M, Lein PJ and Seker E (2016). Mechanisms of Reduced Astrocyte Surface Coverage in Cortical Neuron-Glia Co-cultures on Nanoporous Gold Surfaces. Springer Nature  Cellular and Molecular Bioengineering  vol. 9, (3) 433-442. 10.1007/s12195-016-0449-4
Chapman CAR, Ly S, Wang L, Seker E and Matthews MJ (2016). Utilizing dynamic laser speckle to probe nanoscale morphology evolution in nanoporous gold thin films. Optica Publishing Group  Optics Express  vol. 24, (5) 5323-5333. 10.1364/oe.24.005323
Chapman CAR, Wang L, Biener J, Seker E, Biener MM and Matthews MJ (2016). Engineering on-chip nanoporous gold material libraries via precision photothermal treatment. Royal Society of Chemistry (Rsc)  Nanoscale  vol. 8, (2) 785-795. 10.1039/c5nr04580k
Chapman CAR, Daggumati P, Gott SC, Rao MP and Seker E (2016). Substrate topography guides pore morphology evolution in nanoporous gold thin films. Elsevier  Scripta Materialia  vol. 110, 33-36. 10.1016/j.scriptamat.2015.07.039

2015

Chapman CAR, Chen H, Stamou M, Biener J, Biener MM, Lein PJ and Seker E (2015). Nanoporous Gold as a Neural Interface Coating: Effects of Topography, Surface Chemistry, and Feature Size. American Chemical Society (Acs)  Acs Applied Materials & Interfaces  vol. 7, (13) 7093-7100. 10.1021/acsami.5b00410

2013

Daggumati P, Kurtulus O, Chapman CAR, Dimlioglu D and Seker E (2013). Microfabrication of nanoporous gold patterns for cell-material interaction studies. Myjove Corporation  Journal of Visualized Experiments  (77) 10.3791/50678
Daggumati P, Kurtulus O, Chapman CAR, Dimlioglu D and Seker E (2013). Microfabrication of Nanoporous Gold Patterns for Cell-material Interaction Studies. Myjove Corporation  Journal of Visualized Experiments  (77) 10.3791/50678-v

Grants

Grants of specific relevance to Predictive in vitro Models
Precision cancer treatment through solid-state intratumoural chemotherapeutic delivery via implanted electroactive polymer electrodes
Chapman C
£180,000 Rosetrees Trust (28-12-2020 - 28-12-2023)