Dr Swati Midha
PDRA
School of Engineering and Material Science
Queen Mary University of London
Queen Mary University of London
Research
organ-on-chip, musculoskeletal, in vitro models, stem cells, biomaterials, mechanobiology
Interests
I am currently involved in an EPSRC-funded project at the School of Engineering and Materials Science. By integrating unique materials and various ligand and cell modalities with advanced biofabrication techniques, such as digital light processing, we aim to create a versatile toolkit for spatial tissue patterning. This toolkit will be applicable across a wide range of organ-chip platforms, with a particular emphasis on developing more effective musculoskeletal (MSK) models as demonstrators, including but not limited to bone and cartilage, for understanding and treating MSK disorders.Publications
2025
Mitochondrial heteroplasmy disrupts osteoclast differentiation and bone resorption by impairing respiratory complex ILeng H, Jiang J, Gassner K, Midha S, Justo-Méndez R, Zheng J, Hall T, Luo L et al.
In Cold Spring Harbor Laboratory
02-05-2025
Engineering growth factor gradients to drive spatiotemporal tissue patterning in organ-on-a-chip systemsHopkins T, Midha S, Grossemy S, Screen HRC, Wann AKT, Knight MM
Journal of Tissue Engineering, Sage Publications vol. 16
18-04-2025
Volumetric Imaging and Analysis of Primary Cilia in Musculoskeletal Tissue using the ARL13B-CENTRIN-2 Mouse ModelJohnson T, Midha S, Wann A
Journal of Visualized Experiments, Myjove Corporation (217)
28-03-2025
2022
Three-Dimensional Engineered Peripheral Nerve: Toward a New Era of Patient-Specific Nerve Repair SolutionsSelim OA, Lakhani S, Midha S, Mosahebi A, Kalaskar DM
Tissue Engineering Part B: Reviews, Mary Ann Liebert Inc vol. 28 (2), 295-335.
01-04-2022
Design and In Vivo Testing of Novel Single-Stage Tendon Graft Using Polyurethane Nanocomposite Polymer for Tendon ReconstructionAjam Y, Midha S, Tan ACW, Blunn G, Kalaskar DM
Journal of Plastic, Reconstructive &Amp; Aesthetic Surgery, Elsevier Bv vol. 75 (4), 1467-1475.
01-04-2022
Biofabrication of the osteochondral unit and its applications: Current and future directions for 3D bioprintingSantos-Beato P, Midha S, Pitsillides AA, Miller A, Torii R, Kalaskar DM
Journal of Tissue Engineering, Sage Publications vol. 13
01-01-2022
2021
Study on the cytocompatibility, mechanical and antimicrobial properties of 3D printed composite scaffolds based on PVA/ Gold nanoparticles (AuNP)/ Ampicillin (AMP) for bone tissue engineeringTopsakal A, Midha S, Yuca E, Tukay A, Sasmazel HT, Kalaskar DM, Gunduz O
Materials Today Communications, Elsevier Bv vol. 28, 102458-102458.
01-09-2021
Self – aligned mesoporous titania nanotubes – reduced graphene oxide hybrid surface: A potential scaffold for osteogenesisWadhwa S, Roy S, Mittal N, John AT, Midha S, Mohanty S, Vasanthan KS, Mathur A et al.
International Journal of Materials Research, Walter De Gruyter Gmbh vol. 112 (7), 584-590.
28-07-2021
Recent developments and characterization techniques in Ulag S, Uysal E, Bedir T, Sengor M, Ekren N, Ustundag CB, Midha S, Kalaskar DM et al.
Polymers For Advanced Technologies, Wiley vol. 32 (8), 3287-3296.
20-04-2021
Rapid tumor inhibitionviamagnetic hyperthermia regulated by caspase 3 with time-dependent clearance of iron oxide nanoparticlesChauhan A, Midha S, Kumar R, Meena R, Singh P, Jha SK, Kuanr BK
Biomaterials Science, Royal Society of Chemistry (Rsc) vol. 9 (8), 2972-2990.
01-01-2021
2020
Advances in Dental Implantology using Nanomaterials and Allied Technology ApplicationsMidha S, sybill D
In Advances in Dental Implantology Using Nanomaterials and Allied Technology Applications, Springer Nature
31-10-2020
Tissue-specific mesenchymal stem cell-dependent osteogenesis in highly porous chitosan-based bone analogsMidha S, Jain KG, Bhaskar N, Kaur A, Rawat S, Giri S, Basu B, Mohanty S
Stem Cells Translational Medicine, Oxford University Press (Oup) vol. 10 (2), 303-319.
13-10-2020
2019
Functional Skin Grafts: Where Biomaterials Meet Stem CellsKaur A, Midha S, Giri S, Mohanty S
Stem Cells International, Wiley vol. 2019, 1-20.
01-07-2019
Advances in three‐dimensional bioprinting of bone: Progress and challengesMidha S, Dalela M, Sybil D, Patra P, Mohanty S
Journal of Tissue Engineering and Regenerative Medicine, Wiley
24-04-2019
2018
Antioxidant and antibacterial hydroxyapatite-based biocomposite for orthopedic applicationsPandey A, Midha S, Sharma RK, Maurya R, Nigam VK, Ghosh S, Balani K
Materials Science and Engineering: C, Elsevier Bv vol. 88, 13-24.
01-07-2018
Microporous Hydroxyapatite Ceramic Composites as Tissue Engineering Scaffolds: An Experimental and Computational StudyKanhed S, Awasthi S, Midha S, Nair J, Nisar A, Patel AK, Pandey A, Sharma R et al.
Advanced Engineering Materials, Wiley vol. 20 (7)
22-03-2018
Differential Regulation of Hedgehog and Parathyroid Signaling in Mulberry and Nonmulberry Silk Fibroin Textile BraidsMidha S, Chawla S, Chakraborty J, Chameettachal S, Ghosh S
Acs Biomaterials Science &Amp; Engineering, American Chemical Society (Acs) vol. 4 (2), 595-607.
23-01-2018
Silk‐Based Bioinks for 3D BioprintingChawla S, Midha S, Sharma A, Ghosh S
Advanced Healthcare Materials, Wiley vol. 7 (8)
23-01-2018
2017
Silk-based bioinks for 3D bioprintingMidha S, ghosh S
In Regenerative Medicine: Laboratory to Clinic, Springer
21-09-2017
Nonmulberry Silk Braids Direct Terminal Osteocytic Differentiation through Activation of Wnt-SignalingMidha S, Chameettachal S, Dey E, Ghosh S
Acs Biomaterials Science &Amp; Engineering, American Chemical Society (Acs) vol. 3 (6), 1062-1074.
31-03-2017
2016
Elucidation of differential mineralisation on native and regenerated silk matricesMidha S, Tripathi R, Geng H, Lee PD, Ghosh S
Materials Science and Engineering: C, Elsevier Bv vol. 68, 663-674.
01-11-2016
Regulation of Chondrogenesis and Hypertrophy in Silk Fibroin-Gelatin-Based 3D Bioprinted ConstructsChameettachal S, Midha S, Ghosh S
Acs Biomaterials Science &Amp; Engineering, American Chemical Society (Acs) vol. 2 (9), 1450-1463.
17-08-2016
Osteogenic signaling on silk-based matricesMidha S, Murab S, Ghosh S
Biomaterials, Elsevier Bv vol. 97, 133-153.
01-08-2016
Silk fibroin as biomaterial for bone tissue engineeringMelke J, Midha S, Ghosh S, Ito K, Hofmann S
Acta Biomaterialia, Elsevier Bv vol. 31, 1-16.
01-02-2016
Preservation of biomacromolecular composition and ultrastructure of a decellularized cornea using a perfusion bioreactorNara S, Chameettachal S, Midha S, Murab S, Ghosh S
Rsc Advances, Royal Society of Chemistry (Rsc) vol. 6 (3), 2225-2240.
01-01-2016
2015
Nonmulberry Silk Fibroin Scaffold Shows Superior Osteoconductivity Than Mulberry Silk Fibroin in Calvarial Bone RegenerationSahu N, Baligar P, Midha S, Kundu B, Bhattacharjee M, Mukherjee S, Mukherjee S, Maushart F et al.
Advanced Healthcare Materials, Wiley vol. 4 (11), 1709-1721.
17-06-2015
Effect of visco-elastic silk-chitosan microcomposite scaffolds on matrix deposition and biomechanical functionality for cartilage tissue engineeringChameettachal S, Murab S, Vaid R, Midha S, Ghosh S
Journal of Tissue Engineering and Regenerative Medicine, Wiley vol. 11 (4), 1212-1229.
07-04-2015
Strategies for faster detachment of corneal cell sheet using micropatterned thermoresponsive matricesNara S, Chameettachal S, Midha S, Singh H, Tandon R, Mohanty S, Ghosh S
Journal of Materials Chemistry B, Royal Society of Chemistry (Rsc) vol. 3 (20), 4155-4169.
01-01-2015
2013
Preconditioned 70S30C bioactive glass foams promote osteogenesis in vivoMidha S, Kim TB, van den Bergh W, Lee PD, Jones JR, Mitchell CA
Acta Biomaterialia, Elsevier Bv vol. 9 (11), 9169-9182.
01-11-2013
2012
Bioactive Glass Foam Scaffolds are Remodelled by Osteoclasts and Support the Formation of Mineralized Matrix and Vascular Networks In VitroMidha S, van den Bergh W, Kim TB, Lee PD, Jones JR, Mitchell CA
Advanced Healthcare Materials, Wiley vol. 2 (3), 490-499.
22-10-2012