Dr Neil McCarthy
PhDMRC Career Development Fellow; Senior Lecturer in Immunology
CPM Theme lead - Infectious Disease & Inflammation Models
Centre for Immunobiology, The Blizard Institute
Queen Mary University of London
Queen Mary University of London
Research
Intestine, Inflammation, Candida, Fungus, Crohn's disease, Ulcerative colitis
Interests
The McCarthy lab studies host–pathogen interactions at mucosal surfaces, with a particular focus on γδ T-cells and their role in gut barrier protection against microbial infection and inflammation. The ultimate aim of this work is to understand how γδ T-cell function becomes dysregulated in inflammatory bowel disease (IBD) and could potentially be restored by novel agonist / antagonist immunotherapies.Publications
2025

Kalailingam P, Ngan SC, Iyappan R, Nehchiri A, Mohd-Kahliab K-H, Lee BST, Sharma B, Machan R, Bo ST, Chambers ES, Fajardo VA, Macpherson REK, Liu J, Klentrou P, Tsiani EL, Lim KL, Su IH, Gao Y-G, Richar AM, Kalaria RN, Chen CP, Balion C, de Kleijn D, McCarthy NE and Sze SK
Aging Cell
05-01-2025
2024

Mathew L, Carlson S, Savage M, Pardieu C, Sze N, Munro C, Naglik J, Stagg A, Kok K, Lindsay JO and McCarthy N
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 18 (Supplement_1), i446-i446.
24-01-2024

Ruchti F, Tuor M, Mathew L, McCarthy NE and LeibundGut-Landmann S
Plos Pathogens, Public Library of Science (Plos) vol. 20 (1)
12-01-2024

Tyler CJ, Hoti I, Griffiths DD, Cuff SM, Andrews R, Keisker M, Ahmed R, Hansen HP, Lindsay JO, Stagg AJ, Moser B, McCarthy NE and Eberl M
Discovery Immunology, Oxford University Press (Oup) vol. 3 (1)
01-01-2024
2023

Kalailingam P, Mohd‐Kahliab K, Ngan SC, Iyappan R, Melekh E, Lu T, Zien GW, Sharma B, Guo T, MacNeil AJ, MacPherson RE, Tsiani EL, O'Leary DD, Lim KL, Su IH, Gao Y, Richards AM, Kalaria RN, Chen CP, McCarthy NE and Sze SK
Embo Molecular Medicine, Springer Nature vol. 15 (12)
16-11-2023

Carlson SL, Mathew L, Savage M, Kok K, Lindsay JO, Munro CA and McCarthy NE
Journal of Fungi, Mdpi vol. 9 (11)
14-11-2023

Vinaiphat A, Pazhanchamy K, JebaMercy G, Ngan SC, Leow MK-S, Ho HH, Gao Y-G, Lim KL, Richards AM, de Kleijn DPV, Chen CP, Kalaria RN, Liu J, O’Leary DD, McCarthy NE and Sze SK
Arteriosclerosis Thrombosis and Vascular Biology, Wolters Kluwer vol. 43 (3), 427-442.
26-01-2023
2022

Ngan S-FC, McCarthy NE and Sze SK
Methods in Molecular Biology, Springer Nature vol. 2603, 43-58.
13-11-2022

Mathew L, Savage M, Pardieu C, O’Brien M, Sze SK, Eberl M, Stagg A, Gasparetto M, Kok K, Lindsay J and McCarthy N
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 16 (Supplement_1), i043-i044.
21-01-2022
2021

Hedin CR, McCarthy NE, Louis P, Farquharson FM, McCartney S, Stagg AJ, Lindsay JO and Whelan K
Clinical Nutrition, Elsevier vol. 40 (8), 5009-5019.
23-06-2021

Park JE, JebaMercy G, Pazhanchamy K, Guo X, Ngan SC, Liou KCK, Lynn SE, Ng SS, Meng W, Lim SC, Leow MK-S, Richards AM, Pennington DJ, de Kleijn DPV, Sorokin V, Ho HH, McCarthy NE and Sze SK
Atherosclerosis, Elsevier vol. 324, 58-68.
25-03-2021
2020

McCarthy NE, Stagg AJ, Price CL, Mann ER, Gellatly NL, Al-Hassi HO, Knight SC and Panoskaltsis N
Cancer Immunology Immunotherapy, Springer (Part of Springer Nature)
13-10-2020

Tse SW, Tan CF, Park JE, Gnanasekaran J, Gupta N, Low JK, Yeoh KW, Chng WJ, Tay CY, McCarthy NE, Lim SK and Sze SK
Cancers, Mdpi vol. 12 (10)
11-10-2020

Panoskaltsis N, McCarthy NE, Stagg AJ, Mummery CJ, Husni M, Arebi N, Greenstein D, Price CL, Al-Hassi HO, Koutinas M, Mantalaris A and Knight SC
Cancer Immunology, Immunotherapy, Springer Nature vol. 70 (4), 1127-1142.
08-10-2020

Panoskaltsis N, McCarthy NE and Knight SC
Cancer Immunology, Immunotherapy, Springer Nature vol. 70 (4), 1155-1160.
30-08-2020

Ng SS, Park JE, Meng W, Chen CP, Kalaria RN, McCarthy NE and Sze SK
Acs Omega, American Chemical Society (Acs) vol. 5 (23), 13528-13540.
20-05-2020
2019

Gill US and McCarthy NE
Journal of Hepatology, Elsevier
08-11-2019

Gupta N, Park JE, Tse W, Low JK, Kon OL, McCarthy N and Sze SK
Oncotarget, Impact Journals vol. 10 (57), 5970-5982.
15-10-2019

Cox SR, Lindsay JO, Fromentin S, Stagg AJ, McCarthy NE, Galleron N, Ibraim SB, Roume H, Levenez F, Pons N, Maziers N, Lomer MC, Ehrlich SD, Irving PM and Whelan K
Gastroenterology, Elsevier
02-10-2019
2018

McCarthy NE and Eberl M
Front Immunol, Frontiers Media S.a. vol. 9, 985-985.
07-05-2018

Cox SR, Stagg AJ, Fromentin S, Ehrlich SD, McCarthy NE, Galleron N, Levenez F, Lomer M, Lindsay JO, Irving PM and Whelan K
Gastroenterology, Elsevier vol. 154 (6), s-177.
01-05-2018

Harrow P, McCarthy N, Stagg A and Lindsay J
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 12 (supplement_1), s41-s41.
16-01-2018

Cox S, Stagg A, Fromentin S, Ehrlich D, McCarthy N, Galleron N, Levenez F, Lomer M, Lindsay J, Irving P and Whelan K
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 12 (supplement_1), s87-s87.
16-01-2018
2017

MCCARTHY NE, Tyler CJ, Lindsay JO, Stagg AJ, Moser B and Eberl M
Journal of Immunology, American Association of Immunologists
22-03-2017
2016

Giles EM, Sanders TJ, McCarthy NE, Lung J, Pathak M, MacDonald TT, Lindsay JO and Stagg AJ
Mucosal Immunology, Elsevier vol. 10 (1), 184-193.
25-05-2016

Petty RD, McCarthy NE, Le Dieu R and Kerr JR
Plos One, Public Library of Science (Plos) vol. 11 (3)
11-03-2016
2015

McCarthy NE, Hedin CR, Sanders TJ, Amon P, Hoti I, Ayada I, Baji V, Giles EM, Wildemann M, Bashir Z, Whelan K, Sanderson I, Lindsay JO and Stagg AJ
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 125 (8), 3215-3225.
13-07-2015

Brugha R, Mushtaq N, McCarthy NE, Stagg AJ and Grigg J
Clin Exp Allergy vol. 45 (3), 624-631.
01-03-2015
2014

Sanders TJ, McCarthy NE, Giles EM, Davidson KLM, Haltalli MLR, Hazell S, Lindsay JO and Stagg AJ
Gastroenterology vol. 146 (5)
01-05-2014

Hedin CR, McCarthy NE, Louis P, Farquharson FM, McCartney S, Taylor K, Prescott NJ, Murrells T, Stagg AJ, Whelan K and Lindsay JO
Gut
07-01-2014
2013

McCarthy NE, Bashir Z, Vossenkämper A, Hedin CR, Giles EM, Bhattacharjee S, Brown SG, Sanders TJ, Whelan K, MacDonald TT, Lindsay JO and Stagg AJ
J Immunol vol. 191 (5), 2752-2763.
01-09-2013

Hedin C, McCarthy NE, Louis P, Farquharson F, McCartney S, Taylor K, Prescott NJ, Murrells T, Stagg AJ, Whelan K and Lindsay JO
Gastroenterology, Elsevier vol. 144 (5)
01-05-2013
2012

Mann ER, McCarthy NE, Peake STC, Milestone AN, Al-Hassi HO, Bernardo D, Tee CT, Landy J, Pitcher MC, Cochrane SA, Hart AL, Stagg AJ and Knight SC
Clin Exp Immunol vol. 170 (2), 122-130.
01-11-2012

Mann ER, Bernardo D, Al-Hassi HO, English NR, Clark SK, McCarthy NE, Milestone AN, Cochrane SA, Hart AL, Stagg AJ and Knight SC
Inflamm Bowel Dis vol. 18 (7), 1275-1286.
01-07-2012

Benjamin JL, Hedin CRH, Koutsoumpas A, Ng SC, McCarthy NE, Prescott NJ, Pessoa-Lopes P, Mathew CG, Sanderson J, Hart AL, Kamm MA, Knight SC, Forbes A, Stagg AJ, Lindsay JO and Whelan K
Inflammatory Bowel Diseases vol. 18 (6), 1092-1100.
01-01-2012
2011

Ng SC, Benjamin JL, McCarthy NE, Hedin CRH, Koutsoumpas A, Plamondon S, Price CL, Hart AL, Kamm MA, Forbes A, Knight SC, Lindsay JO, Whelan K and Stagg AJ
Inflamm Bowel Dis vol. 17 (10), 2027-2037.
01-10-2011

Benjamin JL, Hedin CRH, Koutsoumpas A, Ng SC, McCarthy NE, Hart AL, Kamm MA, Sanderson JD, Knight SC, Forbes A, Stagg AJ, Whelan K and Lindsay JO
Gut vol. 60 (7), 923-929.
01-07-2011

Hedin CR, McCarthy NE, Bhattacharjee S, James G, Whelan K, Lindsay JO and Stagg AJ
Gastroenterology, Elsevier vol. 140 (5), s-489.
01-05-2011
2010

Mann ER, Ordiz DB, Al-Hassi HO, Clark SK, McCarthy NE, Milestone AN, Cochrane SA, Hart A, Stagg AJ and Knight SC
Gastroenterology, Elsevier vol. 138 (5), s-745.
01-05-2010
2009

Mann ER, McCarthy NE, Milestone AN, Cochrane SA, Stagg AJ, Hart A and Knight SC
Gastroenterology, Elsevier vol. 136 (5), a-252.
01-05-2009

Mann ER, Al-Hassi HO, Clark SK, McCarthy NE, Cochrane SA, Hart A, Stagg AJ and Knight SC
Gastroenterology, Elsevier vol. 136 (5), a-408.
01-05-2009

Ng SC, McCarthy NE, Plamondon S, Kamm MA, Stagg AJ and Knight SC
Gastroenterology, Elsevier vol. 136 (5), a-262.
01-05-2009

Ng SC, Rigby R, Hart AL, Plamondon S, Gellatly N, McCarthy NE, Al-Hassi HO, Kamm MA, Knight SC and Stagg AJ
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 3 (1), s132-s132.
01-02-2009

Ng SC, McCarthy NE, Plamondon S, Kamm MA, Stagg AJ and Knight SC
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 3 (1), s134-s135.
01-02-2009
2008

Holden NJ, Bedford PA, McCarthy NE, Marks NA, Ind PW, Jowsey IR, Basketter DA and Knight SC
Clin Exp Allergy vol. 38 (7), 1148-1159.
01-07-2008

Ng SC, Koutsoumpas A, Hedin CR, McCarthy NE, Plamondon S, Kamm MA, Knight SC, Forbes A, Lindsay JO, Whelan K and Stagg AJ
Gastroenterology, Elsevier vol. 134 (4)
01-04-2008

Ng SC, Koutsoumpas A, Hedin CRH, McCarthy N, Plamondon S, Kamm MA, Knight SC, Forbes A, Lindsay JO, Whelan K and Stagg AJ
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 2 (1)
01-02-2008
2007

McCarthy NE, Jones HA, Marks NA, Shiner RJ, Ind PW, Al-Hassi HO, English NR, Murray CM, Lambert JR, Knight SC and Stagg AJ
Clin Exp Allergy vol. 37 (1), 72-82.
01-01-2007
Grants

Neil McCarthy
£20,000 TC BioPharm
01-04-2023 - 30-09-2023

Neil McCarthy
£7,000 Barts and the London Charity
22-09-2022 - 21-09-2023

Neil McCarthy
£316,434 ImCheck Therapeutics SAS
02-03-2020 - 31-03-2023

Neil McCarthy
£153,432 Barts and the London Charity
30-09-2019 - 30-06-2023

Neil McCarthy
£556,418 MRC Medical Research Council
02-01-2018 - 30-06-2023