Publications

Publications of specific relevance to Predictive in vitro Models
2020

Ng SS, Park JE, Meng W, Chen CP, Kalaria RN,
Mccarthy NE and Sze SK (2020).
Pulsed SILAM Reveals in Vivo Dynamics of Murine Brain Protein Translation. Acs Omega 10.1021/acsomega.9b044392019

Gupta N, Park JE, Tse W, Low JK, Kon OL,
McCarthy N and Sze SK (2019).
ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer. Impact Journals Oncotarget vol. 10, (57) 5970-5982.
10.18632/oncotarget.27235
Cox SR, Lindsay JO, Fromentin S, Stagg AJ,
McCarthy NE, Galleron N, Ibraim SB, Roume H, Levenez F, Pons N, Maziers N, Lomer MC, Ehrlich SD, Irving PM and Whelan K (2019).
Effects of Low-FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized Trial. Elsevier Gastroenterology 10.1053/j.gastro.2019.09.0242018
2017
MCCARTHY NE, Tyler CJ, Lindsay JO, Stagg AJ, Moser B and Eberl M (2017).
Antigen-presenting human γδ T-cells promote intestinal CD4+ T-cell expression of IL-22 and mucosal release of calprotectin. American Association of Immunologists Journal of Immunology 10.4049/jimmunol.1700003
Giles EM, Sanders TJ,
McCarthy NE, Lung J, Pathak M, Macdonald TT, Lindsay JO and Stagg AJ (2017).
Regulation of human intestinal T-cell responses by type 1 interferon-STAT1 signaling is disrupted in inflammatory bowel disease. Mucosal Immunology vol. 10, (1) 184-193.
10.1038/mi.2016.442016

Petty RD,
McCarthy NE, Le Dieu R and Kerr JR (2016).
MicroRNAs hsa-miR-99b, hsa-miR-330, hsa-miR-126 and hsa-miR-30c: Potential Diagnostic Biomarkers in Natural Killer (NK) Cells of Patients with Chronic Fatigue Syndrome (CFS)/ Myalgic Encephalomyelitis (ME). Plos One vol. 11, (3)
10.1371/journal.pone.01509042015
McCarthy NE, Hedin CR, Sanders TJ, Amon P, Hoti I, Ayada I, Baji V, Giles EM, Wildemann M, Bashir Z, Whelan K, Sanderson I, Lindsay JO and Stagg AJ (2015).
Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn’s disease. American Society For Clinical Investigation Journal of Clinical Investigation vol. 125, (8) 3215-3225.
10.1172/JCI80840
Brugha R, Mushtaq N,
McCarthy NE, Stagg AJ and Grigg J (2015).
Respiratory tract dendritic cells in paediatric asthma. Clin Exp Allergy vol. 45, (3) 624-631.
10.1111/cea.124572014

Sanders TJ,
McCarthy NE, Giles EM, Davidson KLM, Haltalli MLR, Hazell S, Lindsay JO and Stagg AJ (2014).
Increased production of retinoic acid by intestinal macrophages contributes to their inflammatory phenotype in patients with Crohn's disease. Gastroenterology vol. 146, (5)
10.1053/j.gastro.2014.01.057
Hedin CR,
McCarthy NE, Louis P, Farquharson FM, McCartney S, Taylor K, Prescott NJ, Murrells T, Stagg AJ, Whelan K and Lindsay JO (2014).
Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings. Gut 10.1136/gutjnl-2013-3062262013
McCarthy NE, Bashir Z, Vossenkämper A, Hedin CR, Giles EM, Bhattacharjee S, Brown SG, Sanders TJ, Whelan K, MacDonald TT, Lindsay JO and Stagg AJ (2013).
Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cells. J Immunol vol. 191, (5) 2752-2763.
10.4049/jimmunol.12029592012

Mann ER,
McCarthy NE, Peake STC, Milestone AN, Al-Hassi HO, Bernardo D, Tee CT, Landy J, Pitcher MC, Cochrane SA, Hart AL, Stagg AJ and Knight SC (2012).
Skin- and gut-homing molecules on human circulating γδ T cells and their dysregulation in inflammatory bowel disease. Clin Exp Immunol vol. 170, (2) 122-130.
10.1111/j.1365-2249.2012.04649.x
Mann ER, Bernardo D, Al-Hassi HO, English NR, Clark SK,
McCarthy NE, Milestone AN, Cochrane SA, Hart AL, Stagg AJ and Knight SC (2012).
Human gut-specific homeostatic dendritic cells are generated from blood precursors by the gut microenvironment. Inflamm Bowel Dis vol. 18, (7) 1275-1286.
10.1002/ibd.21893
Benjamin JL, Hedin CRH, Koutsoumpas A, Ng SC,
McCarthy NE, Prescott NJ, Pessoa-Lopes P, Mathew CG, Sanderson J, Hart AL, Kamm MA, Knight SC, Forbes A, Stagg AJ, Lindsay JO and Whelan K (2012).
Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota. Inflammatory Bowel Diseases vol. 18, (6) 1092-1100.
10.1002/ibd.218642011

Ng SC, Benjamin JL,
McCarthy NE, Hedin CRH, Koutsoumpas A, Plamondon S, Price CL, Hart AL, Kamm MA, Forbes A, Knight SC, Lindsay JO, Whelan K and Stagg AJ (2011).
Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease. Inflamm Bowel Dis vol. 17, (10) 2027-2037.
10.1002/ibd.21590
Benjamin JL, Hedin CRH, Koutsoumpas A, Ng SC,
McCarthy NE, Hart AL, Kamm MA, Sanderson JD, Knight SC, Forbes A, Stagg AJ, Whelan K and Lindsay JO (2011).
Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease. Gut vol. 60, (7) 923-929.
10.1136/gut.2010.2320252008

Holden NJ, Bedford PA,
McCarthy NE, Marks NA, Ind PW, Jowsey IR, Basketter DA and Knight SC (2008).
Dendritic cells from control but not atopic donors respond to contact and respiratory sensitizer treatment in vitro with differential cytokine production and altered stimulatory capacity. Clin Exp Allergy vol. 38, (7) 1148-1159.
10.1111/j.1365-2222.2008.02997.x2007
McCarthy NE, Jones HA, Marks NA, Shiner RJ, Ind PW, Al-Hassi HO, English NR, Murray CM, Lambert JR, Knight SC and Stagg AJ (2007).
Inhaled allergen-driven CD1c up-regulation and enhanced antigen uptake by activated human respiratory-tract dendritic cells in atopic asthma. Clin Exp Allergy vol. 37, (1) 72-82.
10.1111/j.1365-2222.2006.02631.x