Isaacs JD, Brockbank S, Pedersen AW, Hilkens C, Anderson A, Stocks P, Lendrem D, Tarn J, Smith GR, Allen B, Casement J, Diboll J, Harry R, Cooles FAH, Cope AP, Simpson G, Toward R, Noble H, Parke A, Wu W, Clarke F, Scott D, Scott IC, Galloway J, Lempp H, Ibrahim F, Schwank S, Molyneux G, Lazarov T and Geissmann F (2022). RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients. Scientific Data  vol. 9, (1) 10.1038/s41597-022-01264-y

Elshikh M, El Sayed R, Aly N, Prediletto E, Hands R, Fossati-Jimack L, Bombardieri M, Lewis M and Pitzalis C (2022). POS0431 PDGF-BB, TNF-α, AND LT-β REGULATE FOLLICULAR DENDRITIC CELL DEVELOPMENT IN THE RHEUMATOID SYNOVIUM. Annals of The Rheumatic Diseases  vol. 81, (Suppl 1) 470.1-47470. 10.1136/annrheumdis-2022-eular.3358

Pontarini E, Chowdhury F, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Goldmann K, Fossati-Jimack L, Emery P, Ng WF, Sutcliffe N, Everett C, Fernandez C, Tappuni A, Lewis M, Pitzalis C, Bowman SJ and Bombardieri M (2021). OP0136 RITUXIMAB PREVENTS THE PROGRESSION OF B-CELL DRIVEN INFLAMMATORY INFILTRATE IN THE MINOR SALIVARY GLANDS OF PRIMARY SJOGREN’S SYNDROME BY DOWNREGULATING IMMUNOLOGICAL PATHWAYS KEY IN ECTOPIC GERMINAL CENTRE ORGANIZATION: RESULTS FROM THE TRACTISS TRIAL. Annals of The Rheumatic Diseases  vol. 80, (Suppl 1) 79-80. 10.1136/annrheumdis-2021-eular.3960

Pontarini E, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Fossati-Jimack L, Coleby R, Chowdhury F, Calcaterra F, Tappuni A, Lewis MJ, Fabris M, Quartuccio L, Bella SD, Bowman S, Pitzalis C, Mavilio D, De Vita S and Bombardieri M (2021). NKp30 Receptor Upregulation in Salivary Glands of Sjögren’s Syndrome Characterizes Ectopic Lymphoid Structures and Is Restricted by Rituximab Treatment. Frontiers in Immunology  vol. 12, 10.3389/fimmu.2021.706737

Rivellese F, Pontarini E, Fossati-Jimack L, Moura RA, Romão VC, Fonseca JE, Nerviani A, Cubuk C, Goldmann K, Bombardieri M, Lewis M and Pitzalis C (2021). OP0011 INTEGRATION OF FLOW AND DIGITAL CYTOMETRY IN EARLY TREATMENT-NAÏVE RHEUMATOID ARTHRITIS IDENTIFIES DISTINCT IMMUNOPHENOTYPES IN PERIPHERAL BLOOD AND DISEASE TISSUE. Annals of The Rheumatic Diseases  vol. 80, (Suppl 1) 7.2-7.7. 10.1136/annrheumdis-2021-eular.438

Ferrari M, Onuoha SC, Fossati-Jimack L, Nerviani A, Alves PL, Pagani S, Deantonio C, Colombo F, Santoro C, Sblattero D and Pitzalis C (2021). Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis. Frontiers in Immunology  vol. 12, 10.3389/fimmu.2021.640070

Jackson WD, Gulino A, Fossati-Jimack L, Castro Seoane R, Tian K, Best K, Köhl J, Belmonte B, Strid J and Botto M (2021). C3 Drives Inflammatory Skin Carcinogenesis Independently of C5. Journal of Investigative Dermatology  vol. 141, (2) 404-414.e6. 10.1016/j.jid.2020.06.025

Humby F, Durez P, Buch MH, Lewis MJ, Rizvi H, Rivellese F, Nerviani A, Giorli G, Mahto A, Montecucco C, Lauwerys B, Ng N, Ho P, Bombardieri M, Romão VC, Verschueren P, Kelly S, Sainaghi PP, Gendi N, Dasgupta B, Cauli A, Reynolds P, Cañete JD, Moots R, Taylor PC, Edwards CJ, Isaacs J, Sasieni P, Choy E and Pitzalis C (2021). Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial. The Lancet  vol. 397, (10271) 305-317. 10.1016/S0140-6736(20)32341-2

Pontarini E, Murray-Brown WJ, Croia C, Lucchesi D, Conway J, Rivellese F, Fossati-Jimack L, Astorri E, Prediletto E, Corsiero E, Romana Delvecchio F, Coleby R, Gelbhardt E, Bono A, Baldini C, Puxeddu I, Ruscitti P, Giacomelli R, Barone F, Fisher B, Bowman SJ, Colafrancesco S, Priori R, Sutcliffe N, Challacombe S, Carlesso G, Tappuni A, Pitzalis C and Bombardieri M (2020). Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren's syndrome with ectopic germinal centres and MALT lymphoma. Annals of The Rheumatic Diseases  vol. 79, (12) 1588-1599. 10.1136/annrheumdis-2020-217646

Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C and PEAC- R4RA investigators (2020). B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure. Wiley  Arthritis and Rheumatology  10.1002/art.41184

El Shikh MEM, El Sayed R, Nerviani A, Goldmann K, John CR, Hands R, Fossati-Jimack L, Lewis MJ and Pitzalis C (2019). Extracellular traps and PAD4 released by macrophages induce citrullination and auto-antibody production in autoimmune arthritis. Elsevier Bv  Journal of Autoimmunity  10.1016/j.jaut.2019.06.008

Pontarini E, Lucchesi D, Fossati-Jimack L, Coleby R, Tentorio P, Croia C, Bombardieri M and Mavilio D (2019). NK cell recruitment in salivary glands provides early viral control but is dispensable for tertiary lymphoid structure formation. Journal of Leukocyte Biology  vol. 105, (3) 589-602. 10.1002/JLB.5A1117-462RR

Cope AP, Barnes MR, Belson A, Binks M, Brockbank S, Bonachela-Capdevila F, Carini C, Fisher BA, Goodyear CS, Emery P, Ehrenstein MR, Gozzard N, Harris R, Hollis S, Keidel S, Levesque M, Lindholm C, McDermott MF, McInnes IB, Mela CM, Parker G, Read S, Pedersen AW, Ponchel F, Porter D, Rao R, Rowe A, Schulz-Knappe P, Sleeman MA and Symmons D (2018). The RA-MAP Consortium: a working model for academia-industry collaboration. Nat Rev Rheumatol  vol. 14, (1) 53-60. 10.1038/nrrheum.2017.200

Rivellese F, Mauro D, Nerviani A, Pagani S, Fossati-Jimack L, Messemaker T, Kurreeman FAS, Toes REM, Ramming A, Rauber S, Schett G, Jones GW, Jones SA, Rossi FW, De Paulis A, Marone G, El Shikh MEM, Humby F and Pitzalis C (2018). Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production. Annals of The Rheumatic Diseases  vol. 77, (12) 1773-1781. 10.1136/annrheumdis-2018-213418

Barbour TD, Ling GS, Ruseva MM, Fossati-Jimack L, Cook HT, Botto M and Pickering MC (2016). Complement receptor 3 mediates renal protection in experimental C3 glomerulopathy. Kidney Int  vol. 89, (4) 823-832. 10.1016/j.kint.2015.11.024

Saja MF, Baudino L, Jackson WD, Cook HT, Malik TH, Fossati-Jimack L, Ruseva M, Pickering MC, Woollard KJ and Botto M (2015). Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1(low) Monocytes. Cell Rep  vol. 12, (11) 1802-1815. 10.1016/j.celrep.2015.08.020

Fossati-Jimack L, Ling GS, Baudino L, Szajna M, Manivannan K, Zhao JC, Midgley R, Chai J-G, Simpson E, Botto M and Scott D (2015). Intranasal peptide-induced tolerance and linked suppression: consequences of complement deficiency. Immunology  vol. 144, (1) 149-157. 10.1111/imm.12358

Banda NK, Mehta G, Chao Y, Wang G, Inturi S, Fossati-Jimack L, Botto M, Wu L, Moghimi SM and Simberg D (2014). Mechanisms of complement activation by dextran-coated superparamagnetic iron oxide (SPIO) nanoworms in mouse versus human serum. Part Fibre Toxicol  vol. 11, 10.1186/s12989-014-0064-2

Sattler S, Ling G-S, Xu D, Hussaarts L, Romaine A, Zhao H, Fossati-Jimack L, Malik T, Cook HT, Botto M, Lau Y-L, Smits HH, Liew FY and Huang F-P (2014). IL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut. J Autoimmun  vol. 50, 107-122. 10.1016/j.jaut.2014.01.032

Baudino L, Sardini A, Ruseva MM, Fossati-Jimack L, Cook HT, Scott D, Simpson E and Botto M (2014). C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens. Proc Natl Acad Sci U S A  vol. 111, (4) 1503-1508. 10.1073/pnas.1316877111

Ling GS, Bennett J, Woollard KJ, Szajna M, Fossati-Jimack L, Taylor PR, Scott D, Franzoso G, Cook HT and Botto M (2014). Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages. Nat Commun  vol. 5, 10.1038/ncomms4039

Fossati-Jimack L, Ling GS, Cortini A, Szajna M, Malik TH, McDonald JU, Pickering MC, Cook HT, Taylor PR and Botto M (2013). Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells. Plos One  vol. 8, (2) 10.1371/journal.pone.0057082

Lewis MJ, Malik TH, Fossati-Jimack L, Carassiti D, Cook HT, Haskard DO and Botto M (2012). Distinct roles for complement in glomerulonephritis and atherosclerosis revealed in mice with a combination of lupus and hyperlipidemia. Arthritis and Rheumatism  vol. 64, (8) 2707-2718. 10.1002/art.34451

Tarzi RM, Sharp PEH, McDaid JP, Fossati-Jimack L, Herbert PE, Pusey CD, Cook HT and Warrens AN (2012). Mice with defective Fas ligand are protected from crescentic glomerulonephritis. Kidney Int  vol. 81, (2) 170-178. 10.1038/ki.2011.319

McDonald JU, Cortini A, Rosas M, Fossati-Jimack L, Ling GS, Lewis KJ, Dewitt S, Liddiard K, Brown GD, Jones SA, Hallett MB, Botto M and Taylor PR (2011). In vivo functional analysis and genetic modification of in vitro-derived mouse neutrophils. Faseb J  vol. 25, (6) 1972-1982. 10.1096/fj.10-178517

Santiago-Raber M-L, Amano H, Amano E, Fossati-Jimack L, Swee LK, Rolink A and Izui S (2010). Evidence that Yaa-induced loss of marginal zone B cells is a result of dendritic cell-mediated enhanced activation. J Autoimmun  vol. 34, (4) 349-355. 10.1016/j.jaut.2010.01.001

Carlucci F, Fossati-Jimack L, Dumitriu IE, Heidari Y, Walport MJ, Szajna M, Baruah P, Garden OA, Cook HT and Botto M (2010). Identification and characterization of a lupus suppressor 129 locus on chromosome 3. J Immunol  vol. 184, (11) 6256-6265. 10.4049/jimmunol.0901463

Heidari Y, Fossati-Jimack L, Carlucci F, Walport MJ, Cook HT and Botto M (2009). A lupus-susceptibility C57BL/6 locus on chromosome 3 (Sle18) contributes to autoantibody production in 129 mice. Genes Immun  vol. 10, (1) 47-55. 10.1038/gene.2008.78

Baudino L, Yoshinobu K, Morito N, Kikuchi S, Fossati-Jimack L, Morley BJ, Vyse TJ, Hirose S, Jørgensen TN, Tucker RM, Roark CL, Kotzin BL, Evans LH and Izui S (2008). Dissection of genetic mechanisms governing the expression of serum retroviral gp70 implicated in murine lupus nephritis. J Immunol  vol. 181, (4) 2846-2854. 10.4049/jimmunol.181.4.2846

Fossati-Jimack L, Cortes-Hernandez J, Norsworthy PJ, Cook HT, Walport MJ and Botto M (2008). Regulation of B cell tolerance by 129-derived chromosome 1 loci in C57BL/6 mice. Arthritis Rheum  vol. 58, (7) 2131-2141. 10.1002/art.23553

Fossati-Jimack L, Cortes-Hernandez J, Norsworthy PJ, Walport MJ, Cook HT and Botto M (2008). C1q deficiency promotes the production of transgenic-derived IgM and IgG3 autoantibodies in anti-DNA knock-in transgenic mice. Mol Immunol  vol. 45, (3) 787-795. 10.1016/j.molimm.2007.06.162

Baudino L, Fossati-Jimack L, Chevalley C, Martinez-Soria E, Shulman MJ and Izui S (2007). IgM and IgA anti-erythrocyte autoantibodies induce anemia in a mouse model through multivalency-dependent hemagglutination but not through complement activation. Blood  vol. 109, (12) 5355-5362. 10.1182/blood-2006-11-059899

Carlucci F, Cortes-Hernandez J, Fossati-Jimack L, Bygrave AE, Walport MJ, Vyse TJ, Cook HT and Botto M (2007). Genetic dissection of spontaneous autoimmunity driven by 129-derived chromosome 1 Loci when expressed on C57BL/6 mice. J Immunol  vol. 178, (4) 2352-2360. 10.4049/jimmunol.178.4.2352

Kikuchi S, Santiago-Raber M-L, Amano H, Amano E, Fossati-Jimack L, Moll T, Kotzin BL and Izui S (2006). Contribution of NZB autoimmunity 2 to Y-linked autoimmune acceleration-induced monocytosis in association with murine systemic lupus. J Immunol  vol. 176, (5) 3240-3247. 10.4049/jimmunol.176.5.3240

Tas SW, Quartier P, Botto M and Fossati-Jimack L (2006). Macrophages from patients with SLE and rheumatoid arthritis have defective adhesion in vitro, while only SLE macrophages have impaired uptake of apoptotic cells. Ann Rheum Dis  vol. 65, (2) 216-221. 10.1136/ard.2005.037143

Trendelenburg M, Fossati-Jimack L, Cortes-Hernandez J, Turnberg D, Lewis M, Izui S, Cook HT and Botto M (2005). The role of complement in cryoglobulin-induced immune complex glomerulonephritis. J Immunol  vol. 175, (10) 6909-6914. 10.4049/jimmunol.175.10.6909

Amano H, Amano E, Santiago-Raber M-L, Moll T, Martinez-Soria E, Fossati-Jimack L, Iwamoto M, Rozzo SJ, Kotzin BL and Izui S (2005). Selective expansion of a monocyte subset expressing the CD11c dendritic cell marker in the Yaa model of systemic lupus erythematosus. Arthritis Rheum  vol. 52, (9) 2790-2798. 10.1002/art.21365

Kikuchi S, Amano H, Amano E, Fossati-Jimack L, Santiago-Raber M-L, Moll T, Ida A, Kotzin BL and Izui S (2005). Identification of 2 major loci linked to autoimmune hemolytic anemia in NZB mice. Blood  vol. 106, (4) 1323-1329. 10.1182/blood-2005-02-0558

Kikuchi S, Fossati-Jimack L, Moll T, Amano H, Amano E, Ida A, Ibnou-Zekri N, Laporte C, Santiago-Raber M-L, Rozzo SJ, Kotzin BL and Izui S (2005). Differential role of three major New Zealand Black-derived loci linked with Yaa-induced murine lupus nephritis. J Immunol  vol. 174, (2) 1111-1117. 10.4049/jimmunol.174.2.1111

Cortes-Hernandez J, Fossati-Jimack L, Petry F, Loos M, Izui S, Walport MJ, Cook HT and Botto M (2004). Restoration of C1q levels by bone marrow transplantation attenuates autoimmune disease associated with C1q deficiency in mice. Eur J Immunol  vol. 34, (12) 3713-3722. 10.1002/eji.200425616

Haywood MEK, Rogers NJ, Rose SJ, Boyle J, McDermott A, Rankin JM, Thiruudaian V, Lewis MR, Fossati-Jimack L, Izui S, Walport MJ and Morley BJ (2004). Dissection of BXSB lupus phenotype using mice congenic for chromosome 1 demonstrates that separate intervals direct different aspects of disease. Journal of Immunology  vol. 173, (7) 4277-4285. 10.4049/jimmunol.173.7.4277

Lee NJ, Rigby RJ, Gill H, Boyle JJ, Fossati-Jimack L, Morley BJ and Vyse TJ (2004). Multiple loci are linked with anti-red blood cell antibody production in NZB mice -- comparison with other phenotypes implies complex modes of action. Clin Exp Immunol  vol. 138, (1) 39-46. 10.1111/j.1365-2249.2004.02560.x

Trendelenburg M, Manderson AP, Fossati-Jimack L, Walport MJ and Botto M (2004). Monocytosis and accelerated activation of lymphocytes in C1q-deficient autoimmune-prone mice. Immunology  vol. 113, (1) 80-88. 10.1111/j.1365-2567.2004.01940.x

Kuroki A, Moll T, López-Hoyos M, Fossati-Jimack L, Ibnou-Zekri N, Kikuchi S, Merino J, Merino R and Izui S (2004). Enforced Bcl-2 expression in B lymphocytes induces rheumatoid factor and anti-DNA production, but the Yaa mutation promotes only anti-DNA production. Eur J Immunol  vol. 34, (4) 1077-1084. 10.1002/eji.200424859

Norsworthy PJ, Fossati-Jimack L, Cortes-Hernandez J, Taylor PR, Bygrave AE, Thompson RD, Nourshargh S, Walport MJ and Botto M (2004). Murine CD93 (C1qRp) Contributes to the Removal of Apoptotic Cells in Vivo but Is Not Required for C1q-Mediated Enhancement of Phagocytosis. Journal of Immunology  vol. 172, (6) 3406-3414. 10.4049/jimmunol.172.6.3406

Lajaunias F, Ida A, Kikuchi S, Fossati-Jimack L, Martinez-Soria E, Moll T, Law C-L and Izui S (2003). Differential control of CD22 ligand expression on B and T lymphocytes, and enhanced expression in murine systemic lupus. Arthritis Rheum  vol. 48, (6) 1612-1621. 10.1002/art.11021

Tarzi RM, Davies KA, Robson MG, Fossati-Jimack L, Saito T, Walport MJ and Cook HT (2002). Nephrotoxic nephritis is mediated by Fcgamma receptors on circulating leukocytes and not intrinsic renal cells. Kidney Int  vol. 62, (6) 2087-2096. 10.1046/j.1523-1755.2002.00687.x

Cortes-Hernandez J, Fossati-Jimack L, Carugati A, Potter PK, Walport MJ, Cook HT and Botto M (2002). Murine glomerular mesangial cell uptake of apoptotic cells is inefficient and involves serum-mediated but complement-independent mechanisms. Clin Exp Immunol  vol. 130, (3) 459-466. 10.1046/j.1365-2249.2002.01998.x

Kikuchi S, Pastore Y, Fossati-Jimack L, Kuroki A, Yoshida H, Fulpius T, Araki K, Takahashi S, Lemoine R, Reininger L and Izui S (2002). A transgenic mouse model of autoimmune glomerulonephritis and necrotizing arteritis associated with cryoglobulinemia. J Immunol  vol. 169, (8) 4644-4650. 10.4049/jimmunol.169.8.4644

Kuroki A, Kuroda Y, Kikuchi S, Lajaunias F, Fulpius T, Pastore Y, Fossati-Jimack L, Reininger L, Toda T, Nakata M, Kojima N, Mizuochi T and Izui S (2002). Level of galactosylation determines cryoglobulin activity of murine IgG3 monoclonal rheumatoid factor. Blood  vol. 99, (8) 2922-2928. 10.1182/blood.v99.8.2922

Azeredo da Silveira S, Kikuchi S, Fossati-Jimack L, Moll T, Saito T, Verbeek JS, Botto M, Walport MJ, Carroll M and Izui S (2002). Complement activation selectively potentiates the pathogenicity of the IgG2b and IgG3 isotypes of a high affinity anti-erythrocyte autoantibody. J Exp Med  vol. 195, (6) 665-672. 10.1084/jem.20012024

Mitchell DA, Pickering MC, Warren J, Fossati-Jimack L, Cortes-Hernandez J, Cook HT, Botto M and Walport MJ (2002). C1q deficiency and autoimmunity: the effects of genetic background on disease expression. J Immunol  vol. 168, (5) 2538-2543. 10.4049/jimmunol.168.5.2538

Fossati-Jimack L, Azeredo da Silveira S, Moll T, Kina T, Kuypers FA, Oldenborg P-A, Reininger L and Izui S (2002). Selective increase of autoimmune epitope expression on aged erythrocytes in mice: implications in anti-erythrocyte autoimmune responses. J Autoimmun  vol. 18, (1) 17-25. 10.1006/jaut.2001.0563

Izui S, Fossati-Jimack L, da Silveira SA and Moll T (2001). Isotype-dependent pathogenicity of autoantibodies: analysis in experimental autoimmune hemolytic anemia. Springer Semin Immunopathol  vol. 23, (4) 433-445. 10.1007/s281-001-8169-1

Mizuochi T, Pastore Y, Shikata K, Kuroki A, Kikuchi S, Fulpius T, Nakata M, Fossati-Jimack L, Reininger L, Matsushita M, Fujita T and Izui S (2001). Role of galactosylation in the renal pathogenicity of murine immunoglobulin G3 monoclonal cryoglobulins. Blood  vol. 97, (11) 3537-3543. 10.1182/blood.v97.11.3537

Chicheportiche Y, Fossati-Jimack L, Moll S, Ibnou-Zekri N and Izui S (2000). Down-regulated expression of TWEAK mRNA in acute and chronic inflammatory pathologies. Biochem Biophys Res Commun  vol. 279, (1) 162-165. 10.1006/bbrc.2000.3913

Fossati-Jimack L, Ioan-Facsinay A, Reininger L, Chicheportiche Y, Watanabe N, Saito T, Hofhuis FM, Gessner JE, Schiller C, Schmidt RE, Honjo T, Verbeek JS and Izui S (2000). Markedly different pathogenicity of four immunoglobulin G isotype-switch variants of an antierythrocyte autoantibody is based on their capacity to interact in vivo with the low-affinity Fcgamma receptor III. J Exp Med  vol. 191, (8) 1293-1302. 10.1084/jem.191.8.1293

Hügin AW, Fossati-Jimack L and Izui S (2000). The autoimmune accelerating yaa mutation does not accelerate murine AIDS. Cell Immunol  vol. 200, (2) 76-80. 10.1006/cimm.2000.1611

Izui S, Ibnou-Zekri N, Fossati-Jimack L and Iwamoto M (2000). Lessons from BXSB and related mouse models. Int Rev Immunol  vol. 19, (4-5) 447-472. 10.3109/08830180009055507

Fossati-Jimack L, Reininger L, Chicheportiche Y, Clynes R, Ravetch JV, Honjo T and Izui S (1999). High pathogenic potential of low-affinity autoantibodies in experimental autoimmune hemolytic anemia. J Exp Med  vol. 190, (11) 1689-1696. 10.1084/jem.190.11.1689

Ibnou-Zekri N, Iwamoto M, Fossati L, McConahey PJ and Izui S (1997). Role of the major histocompatibility complex class II Ea gene in lupus susceptibility in mice. Proc Natl Acad Sci U S A  vol. 94, (26) 14654-14659. 10.1073/pnas.94.26.14654

Santiago ML, Fossati L, Jacquet C, Müller W, Izui S and Reininger L (1997). Interleukin-4 protects against a genetically linked lupus-like autoimmune syndrome. J Exp Med  vol. 185, (1) 65-70. 10.1084/jem.185.1.65

Takahashi S, Fossati L, Iwamoto M, Merino R, Motta R, Kobayakawa T and Izui S (1996). Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice. J Clin Invest  vol. 97, (7) 1597-1604. 10.1172/JCI118584

Fossati L, Sobel ES, Iwamoto M, Cohen PL, Eisenberg RA and Izui S (1995). The Yaa gene-mediated acceleration of murine lupus: Yaa- T cells from non-autoimmune mice collaborate with Yaa+ B cells to produce lupus autoantibodies in vivo. Eur J Immunol  vol. 25, (12) 3412-3417. 10.1002/eji.1830251231

Moll S, Menoud PA, Fulpius T, Pastore Y, Takahashi S, Fossati L, Vassalli JD, Sappino AP, Schifferli JA and Izui S (1995). Induction of plasminogen activator inhibitor type 1 in murine lupus-like glomerulonephritis. Kidney Int  vol. 48, (5) 1459-1468. 10.1038/ki.1995.435

Izui S, Iwamoto M, Fossati L, Merino R, Takahashi S and Ibnou-Zekri N (1995). The Yaa gene model of systemic lupus erythematosus. Immunol Rev  vol. 144, 137-156. 10.1111/j.1600-065x.1995.tb00068.x

Merino R, Fossati L, Iwamoto M, Takahashi S, Lemoine R, Ibnou-Zekri N, Pugliatti L, Merino J and Izui S (1995). Effect of long-term anti-CD4 or anti-CD8 treatment on the development of lpr CD4- CD8- double negative T cells and of the autoimmune syndrome in MRL-lpr/lpr mice. J Autoimmun  vol. 8, (1) 33-45. 10.1006/jaut.1995.0003

Fossati L, Iwamoto M, Merino R and Izui S (1995). Selective enhancing effect of the Yaa gene on immune responses against self and foreign antigens. Eur J Immunol  vol. 25, (1) 166-173. 10.1002/eji.1830250128

Herrera PL, Harlan DM, Fossati L, Izui S, Huarte J, Orci L, Vassalli JD and Vassalli P (1994). A CD8+ T-lymphocyte-mediated and CD4+ T-lymphocyte-independent autoimmune diabetes of early onset in transgenic mice. Diabetologia  vol. 37, (12) 1277-1279. 10.1007/BF00399802

Fossati L, Merino R, Iwamoto M, Lemoine R and Izui S (1994). Lack of association of V beta 8+ T cells with lupus-like syndrome in MRL-lpr/lpr mice. Eur J Immunol  vol. 24, (7) 1717-1720. 10.1002/eji.1830240741

Izui S, Berney T, Shibata T, Fulpius T, Fossati L and Merino R (1994). Molecular and cellular basis for pathogenicity of autoantibodies. Tohoku J Exp Med  vol. 173, (1) 15-30. 10.1620/tjem.173.15

Izui S, Merino R, Fossati L and Iwamoto M (1994). The role of the Yaa gene in lupus syndrome. Int Rev Immunol  vol. 11, (3) 211-230. 10.3109/08830189409061728

Izui S, Merino R, Iwamoto M and Fossati L (1994). Mechanisms of genetic control of murine systemic lupus erythematosus. Springer Semin Immunopathol  vol. 16, (2-3) 133-152. 10.1007/BF00197514

Merino R, Iwamoto M, Fossati L, Muniesa P, Araki K, Takahashi S, Huarte J, Yamamura K, Vassalli JD and Izui S (1993). Prevention of systemic lupus erythematosus in autoimmune BXSB mice by a transgene encoding I-E alpha chain. J Exp Med  vol. 178, (4) 1189-1197. 10.1084/jem.178.4.1189

Fossati L, Takahashi S, Merino R, Iwamoto M, Aubry JP, Nose M, Spach C, Motta R and Izui S (1993). An MRL/MpJ-lpr/lpr substrain with a limited expansion of lpr double-negative T cells and a reduced autoimmune syndrome. Int Immunol  vol. 5, (5) 525-532. 10.1093/intimm/5.5.525

Cerny A, Merino R, Fossati L, de Kossodo S, Heusser C, Waldvogel FA, Morse HC and Izui S (1992). Effect of cyclosporin A and zidovudine on immune abnormalities observed in the murine acquired immunodeficiency syndrome. J Infect Dis  vol. 166, (2) 285-290. 10.1093/infdis/166.2.285

Merino R, Fossati L, Lacour M, Lemoine R, Higaki M and Izui S (1992). H-2-linked control of the Yaa gene-induced acceleration of lupus-like autoimmune disease in BXSB mice. Eur J Immunol  vol. 22, (2) 295-299. 10.1002/eji.1830220202

Merino R, Fossati L and Izui S (1992). The lupus-prone BXSB strain: the Yaa gene model of systemic lupus erythematosus. Springer Semin Immunopathol  vol. 14, (2) 141-157. 10.1007/BF00195291

Merino R, Fossati L, Lacour M and Izui S (1991). Selective autoantibody production by Yaa+ B cells in autoimmune Yaa(+)-Yaa- bone marrow chimeric mice. J Exp Med  vol. 174, (5) 1023-1029. 10.1084/jem.174.5.1023

Reininger L, Shibata T, Schurmans S, Merino R, Fossati L, Lacour M and Izui S (1990). Spontaneous production of anti-mouse red blood cell autoantibodies is independent of the polyclonal activation in NZB mice. Eur J Immunol  vol. 20, (11) 2405-2410. 10.1002/eji.1830201107

Fossati L, Merino J and Izui S (1990). CD4+ T cells play a major role for IgM and IgG anti-DNA production in mice infected with Plasmodium yoelii. Clin Exp Immunol  vol. 79, (2) 291-296. 10.1111/j.1365-2249.1990.tb05193.x