Dr David Wareham
Clinical Senior Lecturer
Centre for Immunobiology, Blizard Institute
Faculty of Medicine and Dentistry, Queen Mary University of London
Faculty of Medicine and Dentistry, Queen Mary University of London
Publications
2023
Amulele AV, Ong’ayo G, Arara AM, Machanja EW, Etyang A, Aliyan NA, Wareham DW, Berkley JA and Gordon NC (2023). Recurrent spontaneous Escherichia coli meningitis in an adult: a case report. Oxford University Press (Oup) Jac-Antimicrobial Resistance vol. 5, (2) 10.1093/jacamr/dlad029
2022
Stevenson DR, Cherian BP, Kinzig M, Sörgel F and Wareham DW (2022). Intravenous cefiderocol for neurosurgical meningitis from an extensively drug-resistant New-Delhi metallo-β-lactamase-producing Pseudomonas aeruginosa strain. Elsevier Journal of Global Antimicrobial Resistance vol. 32, 29-30. 10.1016/j.jgar.2022.11.019
Bean DC and Wareham DW (2022). Corrigendum to ‘Draft genome sequence of a multidrug-resistant Pseudomonas aeruginosa producing blaSIM metallo-β-lactamase: London, UK’ [Journal of Global Antimicrobial Resistance 29 (2022) 222-224]. Elsevier Journal of Global Antimicrobial Resistance vol. 30, 10.1016/j.jgar.2022.07.013
Ledda A, Cummins M, Shaw LP, Jauneikaite E, Cole K, Lasalle F, Barry D, Turton J, Rosmarin C, Anaraki S, Wareham D, Stoesser N, Paul J, Manuel R, Cherian BP and Didelot X (2022). Hospital outbreak of carbapenem-resistant Enterobacterales associated with a bla OXA-48 plasmid carried mostly by Escherichia coli ST399. Microbiology Society Microbial Genomics vol. 8, (4) 10.1099/mgen.0.000675
Bean DC and Wareham DW (2022). Draft genome sequence of a multidrug-resistant Pseudomonas aeruginosa producing bla SIM metallo-β-lactamase: London, UK. Elsevier Journal of Global Antimicrobial Resistance vol. 29, 222-224. 10.1016/j.jgar.2022.03.022
Stevenson DR, Cherian BP, Kinzig M, Sörgel F and Wareham DW (2022). P44 Nosocomial neurosurgical meningitis due to XDR Pseudomonas aeruginosa: clinical experience with cefiderocol. Oxford University Press (Oup) Jac-Antimicrobial Resistance vol. 4, (Supplement_1) 10.1093/jacamr/dlac004.043
Wareham D, Attwood M, Casey AL, Coyne M, Hughes D, Lister M, Nahl J, Perry JD, Henriksen AS and Longshaw C (2022). P43 In vitro activity of cefiderocol and comparators against Gram-negative pathogens: ARTEMIS study in the UK. Oxford University Press (Oup) Jac-Antimicrobial Resistance vol. 4, (Supplement_1) 10.1093/jacamr/dlac004.042
2021
Shi Y, Wareham DW, Yuan Y, Deng X, Mata A and Azevedo HS (2021). Polymyxin B-Triggered Assembly of Peptide Hydrogels for Localized and Sustained Release of Combined Antimicrobial Therapy. Advanced Healthcare Materials 10.1002/adhm.202101465
Mabayoje DA, NicFhogartaigh C, Cherian BP, Tan MGM and Wareham DW (2021). Compassionate use of cefiderocol for carbapenem-resistant Acinetobacter baumannii prosthetic joint infection. Oxford University Press (Oup) Jac-Antimicrobial Resistance vol. 3, (Supplement_1) i21-i24. 10.1093/jacamr/dlab055
Montag D, Delgado CA, Quispe C, Wareham D, Gallo V, Sanchez-Choy J, Sánchez V, Anaya R, Flores E, Roca L, Mamani V, Medina JR, Velasquez P, Del Aguila C, Prendergast A and Palomino J (2021). Launching of the Anaemia Research Peruvian Cohort (ARPEC): a multicentre birth cohort project to explore the iron adaptive homeostasis, infant growth and development in three Peruvian regions. Bmj Bmj Open vol. 11, (5) 10.1136/bmjopen-2020-045609
McCarthy RR, Larrouy-Maumus GJ, Meiqi Tan MGC and Wareham DW (2021). Antibiotic Resistance Mechanisms and Their Transmission in Acinetobacter baumannii. Microbial Pathogenesis Springer Nature 10.1007/978-3-030-67452-6_7
2020
Lampejo T, Cherian BP, Tan MGM and Wareham DW (2020). Cefiderocol in the treatment of systemic carbapenemase-producing multidrug-resistant Klebsiella pneumoniae infection. Elsevier Journal of Global Antimicrobial Resistance vol. 23, 338-339. 10.1016/j.jgar.2020.10.008
Bean DC, Wigmore SM, Momin MHFA and Wareham DW (2020). Polymyxin Resistant Bacteria in Australian Poultry. Frontiers Frontiers in Sustainable Food Systems vol. 4, 10.3389/fsufs.2020.550318
Wareham DW, Momin MHFA, Phee LM, Hornsey M and Standing JF (2020). Cefepime/sulbactam as an enhanced antimicrobial combination therapy for the treatment of MDR Gram-negative infections—authors’ response. Oxford University Press (Oup) Journal of Antimicrobial Chemotherapy vol. 75, (9) 2713-2713. 10.1093/jac/dkaa270
Maslova E, Shi Y, Sjöberg F, Azevedo HS, Wareham DW and McCarthy RR (2020). An Invertebrate Burn Wound Model That Recapitulates the Hallmarks of Burn Trauma and Infection Seen in Mammalian Models. Frontiers Media Sa Frontiers in Microbiology vol. 11, 10.3389/fmicb.2020.00998
Shi Y, Wareham DW, Phee LM and Azevedo HS (2020). CHAPTER 12 Self-assembled Peptide Nanostructures for Antibacterial Applications. Peptide-Based Biomaterials Royal Society of Chemistry (Rsc) 10.1039/9781839161148-00395
2019
Day MJ, Hopkins KL, Wareham DW, Toleman MA, Elviss N, Randall L, Teale C, Cleary P, Wiuff C, Doumith M, Ellington MJ, Woodford N and Livermore DM (2019). Extended-spectrum β-lactamase-producing Escherichia coli in human-derived and foodchain-derived samples from England, Wales, and Scotland: an epidemiological surveillance and typing study. Elsevier The Lancet Infectious Diseases vol. 19, (12) 1325-1335. 10.1016/s1473-3099(19)30273-7
Wareham DW, Momin MHFA, Phee LM, Hornsey M and Standing JF (2019). Cefepime/sulbactam as an enhanced antimicrobial combination therapy for the treatment of MDR Gram-negative infections. Oxford University Press (Oup) Journal of Antimicrobial Chemotherapy vol. 75, (1) 135-139. 10.1093/jac/dkz420
Abdul Momin MHF, Liakopoulos A, Bean DC, Phee LM and Wareham DW (2019). A novel plasmid-mediated polymyxin resistance determinant (mcr-1.8) in Escherichia coli recovered from broiler chickens in Brunei Darussalam. J Antimicrob Chemother 10.1093/jac/dkz352
Phee L and Wareham D (2019). Detecting Antimicrobial Resistance. Tutorial Topics in Infection For The Combined Infection Training Programme Oxford University Press (Oup) 10.1093/oso/9780198801740.003.0056
Bean DC, Agarwal A, Cherian BP and Wareham DW (2019). Hypermucoviscous polymyxin-resistant Klebsiella pneumoniae from Kolkata, India: Genomic and phenotypic analysis. Elsevier Journal of Global Antimicrobial Resistance vol. 17, 1-2. 10.1016/j.jgar.2019.02.012
Phee LM, Kloprogge F, Morris R, Barrett J, Wareham DW and Standing JF (2019). Pharmacokinetic-pharmacodynamic modelling to investigate in vitro synergy between colistin and fusidic acid against MDR Acinetobacter baumannii. Oxford University Press (Oup) Journal of Antimicrobial Chemotherapy vol. 74, (4) 961-969. 10.1093/jac/dky524
2018
Hornsey M, Betts JW, Mehat JW, Wareham DW, van Vliet AHM, Woodward MJ and La Ragione RM (2018). Characterization of a colistin-resistant Avian Pathogenic Escherichia coli ST69 isolate recovered from a broiler chicken in Germany. J Med Microbiol vol. 68, (1) 111-114. 10.1099/jmm.0.000882
Livermore DM, Day M, Cleary P, Hopkins KL, Toleman MA, Wareham DW, Wiuff C, Doumith M and Woodford N (2018). OXA-1 β-lactamase and non-susceptibility to penicillin/β-lactamase inhibitor combinations among ESBL-producing Escherichia coli. Oxford University Press (Oup) Journal of Antimicrobial Chemotherapy vol. 74, (2) 326-333. 10.1093/jac/dky453
Wareham DW, Phee LM and Abdul Momin MHF (2018). Direct detection of carbapenem resistance determinants in clinical specimens using immunochromatographic lateral flow devices. J Antimicrob Chemother vol. 73, (7) 1997-1998. 10.1093/jac/dky095
WAREHAM DW (2018). Effects of In vivo Emergent Tigecycline Resistance on the Pathogenic Potential of Acinetobacter baumannii. Nature Publishing Group Scientific Reports 10.1038/s41598-018-22549-6
Betts JW, Abdul Momin HF, Phee LM and Wareham DW (2018). Comparative activity of tedizolid and glycopeptide combination therapies for the treatment of Staphylococcus aureus infections: an in vitro and in vivo evaluation against strains with reduced susceptibility to glycopeptides. J Med Microbiol vol. 67, (2) 265-271. 10.1099/jmm.0.000671
2017
Woodford N, Xu-McCrae L, Mushtaq S, Wu HHT, Ellington MJ, Lancaster O, Davies F, Donaldson H, Rao GG, Verma A, Wareham DW, Ciesielczuk H, Stone GG, Irani PM, Bracher S and Hawkey PM (2017). Prevalence of carbapenem resistance and carbapenemase production among Enterobacteriaceae isolated from urine in the UK: results of the UK infection-Carbapenem Resistance Evaluation Surveillance Trial (iCREST-UK). Oxford University Press (Oup) Journal of Antimicrobial Chemotherapy vol. 73, (3) 698-702. 10.1093/jac/dkx471
Abdul Momin MHF, Bean DC, Hendriksen RS, Haenni M, Phee LM and Wareham DW (2017). CHROMagar COL-APSE: a selective bacterial culture medium for the isolation and differentiation of colistin-resistant Gram-negative pathogens. J Med Microbiol vol. 66, (11) 1554-1561. 10.1099/jmm.0.000602
Ciesielczuk H, Phee LM, Dolphin H, Wilks M, Cherian BP and Wareham DW (2017). Optimal detection of carbapenemase-producing Enterobacteriaceae from rectal samples: a role for enrichment? Elsevier Journal of Hospital Infection vol. 98, (3) 270-274. 10.1016/j.jhin.2017.10.012
WAREHAM DW (2017). A Drug to Consider Re-purposing in the Targeted Treatment of Multi-drug Resistant Bacterial Infections? Journal of Laboratory and Precision Medicine vol. 2, (49) 10.21037/jlpm.2017.06.18
Abdul Momin MHF, Liakopoulos A and Wareham DW (2017). Draft Genome Sequence of a Multidrug-Resistant Sequence Type 231 Outbreak-Associated Clone of Klebsiella pneumoniae, KP41-2015, Producing OXA-232 Carbapenemase. Genome Announc vol. 5, (27) 10.1128/genomeA.00604-17
Betts JW, Hornsey M, Wareham DW and La Ragione RM (2017). In vitro and In vivo Activity of Theaflavin-Epicatechin Combinations versus Multidrug-Resistant Acinetobacter baumannii. Infect Dis Ther 10.1007/s40121-017-0161-2
Abdul Momin MHF, Liakopoulos A, Phee LM and Wareham DW (2017). Emergence and nosocomial spread of carbapenem-resistant OXA-232-producing Klebsiella pneumoniae in Brunei Darussalam. Elsevier J Glob Antimicrob Resist vol. 9, 96-99. 10.1016/j.jgar.2017.02.008
Tängdén T, Ramos Martín V, Felton TW, Nielsen EI, Marchand S, Brüggemann RJ, Bulitta JB, Bassetti M, Theuretzbacher U, Tsuji BT, Wareham DW, Friberg LE, De Waele JJ, Tam VH and Roberts JA (2017). The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections. Springer Nature Intensive Care Medicine vol. 43, (7) 1021-1032. 10.1007/s00134-017-4780-6
Cahill ST, Cain R, Wang DY, Lohans CT, Wareham DW, Oswin HP, Mohammed J, Spencer J, Fishwick CWG, McDonough MA, Schofield CJ and Brem J (2017). Cyclic Boronates Inhibit All Classes of β-Lactamases. American Society For Microbiology Antimicrobial Agents and Chemotherapy vol. 61, (4) e02260-e02216. 10.1128/aac.02260-16
Wareham DW and Abdul Momin MHF (2017). Rapid Detection of Carbapenemases in Enterobacteriaceae: Evaluation of the Resist-3 O.K.N. (OXA-48, KPC, NDM) Lateral Flow Multiplexed Assay. J Clin Microbiol vol. 55, (4) 1223-1225. 10.1128/JCM.02471-16
Liakopoulos A, Oikonomou O and Wareham DW (2017). Draft Genome Sequence of Providencia stuartii PS71, a Multidrug-Resistant Strain Associated with Nosocomial Infections in Greece. Genome Announc vol. 5, (12) 10.1128/genomeA.00056-17
Lüthje P, Pranada AB, Carruthers-Lay D, Desjardins M, Gaillot O, Wareham D, Ciesielczuk H and Özenci V (2017). Identification of microorganisms grown on chromogenic media by MALDI-TOF MS. Elsevier Journal of Microbiological Methods vol. 136, 17-20. 10.1016/j.mimet.2017.03.001
WAREHAM DW (2017). Draft Genome Sequence of a Canine Isolate of Methicillin-Resistant Staphylococcus haemolyticus. American Society For Microbiology Genome Announcements 10.1128/genomeA.00146-17
Bean DC, Wigmore SM and Wareham DW (2017). Draft Genome Sequence of Staphylococcus cohnii subsp. urealyticus Isolated from a Healthy Dog. Genome Announc vol. 5, (7) 10.1128/genomeA.01628-16
2016
Li G-B, Abboud MI, Brem J, Someya H, Lohans CT, Yang S-Y, Spencer J, Wareham DW, McDonough MA and Schofield CJ (2016). NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors. Chem Sci vol. 8, (2) 928-937. 10.1039/c6sc04524c
Oikonomou O, Liakopoulos A, Phee LM, Betts J, Mevius D and Wareham DW (2016). Providencia stuartii Isolates from Greece: Co-Carriage of Cephalosporin ( bla SHV-5 , bla VEB-1 ), Carbapenem ( bla VIM-1 ), and Aminoglycoside ( rmtB ) Resistance Determinants by a Multidrug-Resistant Outbreak Clone. Microbial Drug Resistance vol. 22, (5) 379-386. 10.1089/mdr.2015.0215
Betts JW, Sharili AS, La Ragione RM and Wareham DW (2016). In Vitro Antibacterial Activity of Curcumin–Polymyxin B Combinations against Multidrug-Resistant Bacteria Associated with Traumatic Wound Infections. Journal of Natural Products vol. 79, (6) 1702-1706. 10.1021/acs.jnatprod.6b00286
Ciesielczuk H, Jenkins C, Chattaway M, Doumith M, Hope R, Woodford N and Wareham DW (2016). Trends in ExPEC serogroups in the UK and their significance. European Journal of Clinical Microbiology & Infectious Diseases 10.1007/s10096-016-2707-8
Martínez-Guitián M, Vázquez-Ucha JC, Odingo J, Parish T, Poza M, Waite RD, Bou G, Wareham DW and Beceiro A (2016). Synergy between Colistin and the Signal Peptidase Inhibitor MD3 Is Dependent on the Mechanism of Colistin Resistance in Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy vol. 60, (7) 4375-4379. 10.1128/AAC.00510-16
Millar MR, Seale J, Turton J, Wilks M, Costeloe K, Woodford N, Juszczak E, Whiley A, Panton N and Wareham DW (2016). ESBL-producing Enterobacteriaceae in 24 neonatal units and associated networks in the south of England: no clustering of ESBL-producing Escherichia coli in units or networks. Oxford University Press (Oup) Journal of Antimicrobial Chemotherapy vol. 71, (5) 1174-1177. 10.1093/jac/dkv459
Betts JW, Phee LM, Momin MHFA, Umland K-D, Brem J, Schofield CJ and Wareham DW (2016). In vitro and in vivo activity of ML302F: a thioenolate inhibitor of VIM-subfamily metallo β-lactamses. Royal Society of Chemistry (Rsc) Rsc Medicinal Chemistry vol. 7, (1) 190-193. 10.1039/c5md00380f
2015
Betts JW, Phee LM and Wareham DW (2015). Rifaximin combined with polymyxins: A potential regimen for selective decontamination of multidrug-resistant bacteria in the digestive tract? Elsevier Journal of Global Antimicrobial Resistance vol. 4, 11-15. 10.1016/j.jgar.2015.11.008
Wareham DW, Shah R, Betts JW, Phee LM and Momin MHFA (2015). Evaluation of an Immunochromatographic Lateral Flow Assay (OXA-48 K-SeT) for Rapid Detection of OXA-48-Like Carbapenemases in Enterobacteriaceae. American Society For Microbiology Journal of Clinical Microbiology vol. 54, (2) 471-473. 10.1128/jcm.02900-15
Ciesielczuk H, Doumith M, Hope R, Woodford N and Wareham DW (2015). Characterization of the extra-intestinal pathogenic Escherichia coli ST131 clone among isolates recovered from urinary and bloodstream infections in the United Kingdom. Microbiology Society Journal of Medical Microbiology vol. 64, (12) 1496-1503. 10.1099/jmm.0.000179
Niebel M, Quick J, Prieto AMG, Hill RLR, Pike R, Huber D, David M, Hornsey M, Wareham D, Oppenheim B, Woodford N, van Schaik W and Loman N (2015). Deletions in a ribosomal protein-coding gene are associated with tigecycline resistance in Enterococcus faecium. Elsevier International Journal of Antimicrobial Agents vol. 46, (5) 572-575. 10.1016/j.ijantimicag.2015.07.009
Betts JW, Sharili AS, Phee LM and Wareham DW (2015). In Vitro Activity of Epigallocatechin Gallate and Quercetin Alone and in Combination versus Clinical Isolates of Methicillin-Resistant Staphylococcus aureus. American Chemical Society (Acs) Journal of Natural Products vol. 78, (8) 2145-2148. 10.1021/acs.jnatprod.5b00471
WAREHAM DW, Phee LM and Betts JW (2015). Colistin and Fusidic acid: A Novel Potent Synergistic Combination for the Treatment of Acinetobacter baumannii Infection. 10.1128/AAC.00753-15
Ciesielczuk H, Betts J, Phee L, Doumith M, Hope R, Woodford N and Wareham DW (2015). Comparative virulence of urinary and bloodstream isolates of extra-intestinal pathogenic Escherichia coli in a Galleria mellonella model. Taylor & Francis Virulence vol. 6, (2) 145-151. 10.4161/21505594.2014.988095
Makena A, Brem J, Pfeffer I, Geffen REJ, Wilkins SE, Tarhonskaya H, Flashman E, Phee LM, Wareham DW and Schofield CJ (2015). Biochemical characterization of New Delhi metallo-β-lactamase variants reveals differences in protein stability. J Antimicrob Chemother vol. 70, (2) 463-469. 10.1093/jac/dku403
2014
Personne Y, Curtis MA, Wareham DW and Waite RD (2014). Activity of the type I signal peptidase inhibitor MD3 against multidrug-resistant Gram-negative bacteria alone and in combination with colistin. J Antimicrob Chemother vol. 69, (12) 3236-3243. 10.1093/jac/dku309
Phee L, Bharathan B and Wareham DW (2014). 481Successful Treatment of Multi-drug Resistant Acinetobacter baumannii Ventilator-Associated Pneumonia with a Novel Colistin and Fusidic Acid Combination Therapy. Oxford University Press (Oup) Open Forum Infectious Diseases vol. 1, (suppl_1) s179-s179. 10.1093/ofid/ofu052.347
Betts JW, Phee LM, Woodford N and Wareham DW (2014). Activity of colistin in combination with tigecycline or rifampicin against multidrug-resistant Stenotrophomonas maltophilia. Eur J Clin Microbiol Infect Dis vol. 33, (9) 1565-1572. 10.1007/s10096-014-2101-3
Betts JW and Wareham DW (2014). In vitro activity of curcumin in combination with epigallocatechin gallate (EGCG) versus multidrug-resistant Acinetobacter baumannii. Bmc Microbiol vol. 14, 10.1186/1471-2180-14-172
Betts JW, Phee LM, Hornsey M, Woodford N and Wareham DW (2014). In vitro and in vivo activities of tigecycline-colistin combination therapies against carbapenem-resistant Enterobacteriaceae. Antimicrob Agents Chemother vol. 58, (6) 3541-3546. 10.1128/AAC.02449-14
Cheng F, Betts JW, Kelly SM, Wareham DW, Kornherr A, Dumestre F, Schaller J and Heinze T (2014). Whiter, brighter, and more stable cellulose paper coated with antibacterial carboxymethyl starch stabilized ZnO nanoparticles. Journal of Materials Chemistry B vol. 2, (20) 3057-3064. 10.1039/c3tb21734e
Cheng F, BETTS JW, Kelly SM, Wareham DW, Kornherr A, Dumestre F, Schaller J and Heinze T (2014). Whiter, brighter, and more stable cellulose paper coated with antibacterial carboxymethyl starch stabilized ZnO nanoparticles., Editors: McKenzie F. Royal Journals of Materials Chemistry B: Materials For Biology and Medicine vol. 2, 3057-3064. 10.1039/C4TB00548A
Woodford N, Wareham DW, Guerra B and Teale C (2014). Carbapenemase-producing enterobacteriaceae and non-enterobacteriaceae from animals and the environment: An emerging public health risk of our own making? Journal of Antimicrobial Chemotherapy vol. 69, (2) 287-291. 10.1093/jac/dkt392
2013
Ciesielczuk H, Hornsey M, Choi V, Woodford N and Wareham DW (2013). Development and evaluation of a multiplex PCR for eight plasmid-mediated quinolone-resistance determinants. J Med Microbiol vol. 62, (Pt 12) 1823-1827. 10.1099/jmm.0.064428-0
Ciesielczuk H, Hornsey M, Choi V, Woodford N and Wareham DW (2013). Development and evaluation of a multiplex PCR for eight plasmid-mediated quinolone-resistance determinants. Journal of Medical Microbiology vol. 62, (PART 12) 1823-1827. 10.1099/jmm.0.064428-0
Phee L, Hornsey M and Wareham DW (2013). In vitro activity of daptomycin in combination with low-dose colistin against a diverse collection of Gram-negative bacterial pathogens. Eur J Clin Microbiol Infect Dis vol. 32, (10) 1291-1294. 10.1007/s10096-013-1875-z
Hornsey M, Phee L, Stubbings W and Wareham DW (2013). In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens. International Journal of Antimicrobial Agents vol. 42, (4) 343-346. 10.1016/j.ijantimicag.2013.05.010
Phee L, Hornsey M and Wareham DW (2013). In vitro activity of daptomycin in combination with low-dose colistin against a diverse collection of Gram-negative bacterial pathogens. European Journal of Clinical Microbiology and Infectious Diseases vol. 32, (10) 1291-1294. 10.1007/s10096-013-1875-z
Betts JW, Wareham DW, Haswell SJ and Kelly SM (2013). Antifungal synergy of theaflavin and epicatechin combinations against Candida albicans. J Microbiol Biotechnol vol. 23, (9) 1322-1326. 10.4014/jmb.1303.03010
Wareham D, Phee L and Hornsey M (2013). P317 Isolation and characterisation of a novel Nesterenkonia species from a human bloodstream infection. Elsevier International Journal of Antimicrobial Agents vol. 42, s141-s142. 10.1016/s0924-8579(13)70558-2
Hornsey M, Phee L, Woodford N, Turton J, Meunier D, Thomas C and Wareham DW (2013). Evaluation of three selective chromogenic media, CHROMagar ESBL, CHROMagar CTX-M and CHROMagar KPC, for the detection of Klebsiella pneumoniae producing OXA-48 carbapenemase. J Clin Pathol vol. 66, (4) 348-350. 10.1136/jclinpath-2012-201234
Hornsey M, Phee L, Woodford N, Turton J, Meunier D, Thomas C and Wareham DW (2013). Evaluation of three selective chromogenic media, CHROMagar ESBL, CHROMagar CTX-M and CHROMagar KPC, for the detection of Klebsiella pneumoniae producing OXA-48 carbapenemase. Journal of Clinical Pathology vol. 66, (4) 348-350. 10.1136/jclinpath-2012-201234
Hornsey M, Phee L, Longshaw C and Wareham DW (2013). In vivo efficacy of telavancin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection. Int J Antimicrob Agents vol. 41, (3) 285-287. 10.1016/j.ijantimicag.2012.11.013
Hornsey M, Phee L, Longshaw C and Wareham DW (2013). In vivo efficacy of telavancin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection. International Journal of Antimicrobial Agents vol. 41, (3) 285-287. 10.1016/j.ijantimicag.2012.11.013
Hornsey M, Phee L, Stubbings W and Wareham DW (2013). In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens. International Journal of Antimicrobial Agents 10.1016/j.ijantimicag.2013.05.010
Baillie S, Ireland K, Warwick S, Wareham D and Wilks M (2013). Matrix-assisted laser desorption/ionisation-time of flight mass spectrometry: rapid identification of bacteria isolated from patients with cystic fibrosis. Br J Biomed Sci vol. 70, (4) 144-148. 10.1080/09674845.2013.11669948
2012
Hornsey M, Longshaw C, Phee L and Wareham DW (2012). In vitro activity of telavancin in combination with colistin versus Gram-negative bacterial pathogens. Antimicrob Agents Chemother vol. 56, (6) 3080-3085. 10.1128/AAC.05870-11
Waite RD, Wareham DW, Gardiner S and Whiley RA (2012). A Simple, Semiselective Medium for Anaerobic Isolation of Anginosus Group Streptococci from Patients with Chronic Lung Disease. American Society For Microbiology Journal of Clinical Microbiology vol. 50, (4) 1430-1432. 10.1128/jcm.06184-11
Hidalgo L, Hopkins KL, Wareham DW, Gutierrez B and Gonzalez-Zorn B (2012). Association of Extended-Spectrum β-Lactamase VEB-5 and 16S rRNA Methyltransferase ArmA in Salmonella enterica from the United Kingdom. Antimicrobial Agents and Chemotherapy vol. 56, (9) 4985-4987. 10.1128/AAC.00381-12
2011
Hornsey M, Phee L and Wareham DW (2011). A novel variant, NDM-5, of the New Delhi metallo-β-lactamase in a multidrug-resistant Escherichia coli ST648 isolate recovered from a patient in the United Kingdom. Antimicrob Agents Chemother vol. 55, (12) 5952-5954. 10.1128/AAC.05108-11
Hornsey M and Wareham DW (2011). In vivo efficacy of glycopeptide-colistin combination therapies in a Galleria mellonella model of Acinetobacter baumannii infection. Antimicrob Agents Chemother vol. 55, (7) 3534-3537. 10.1128/AAC.00230-11
Hornsey M, Loman N, Wareham DW, Ellington MJ, Pallen MJ, Turton JF, Underwood A, Gaulton T, Thomas CP, Doumith M, Livermore DM and Woodford N (2011). Whole-genome comparison of two Acinetobacter baumannii isolates from a single patient, where resistance developed during tigecycline therapy. J Antimicrob Chemother vol. 66, (7) 1499-1503. 10.1093/jac/dkr168
Reddy S, Rangaiah J, Addiman S, Wareham D, Wilson P and Sefton A (2011). Epidemiology, antibiotic resistance trends and the cost of enteric fever in East London, 2005-2010. Travel Med Infect Dis vol. 9, (4) 206-212. 10.1016/j.tmaid.2011.03.003
Wareham DW, Gordon NC and Hornsey M (2011). In vitro activity of teicoplanin combined with colistin versus multidrug-resistant strains of Acinetobacter baumannii. J Antimicrob Chemother vol. 66, (5) 1047-1051. 10.1093/jac/dkr069
Phee L, Gordon N, Hornsey M and Wareham D (2011). De-escalation of antimicrobial therapy in Gram-negative sepsis: easier said than done? Springer Nature Critical Care vol. 15, (Suppl 1) 10.1186/cc9639
Wareham DW and Gordon NC (2011). Modifications to CHROMagar Acinetobacter for improved selective growth of multi-drug resistant Acinetobacter baumannii. J Clin Pathol vol. 64, (2) 164-167. 10.1136/jcp.2010.083469
Shah A and Wareham D (2011). EVALUATION OF RAPID E TEST MIC TESTING USING CHROM AGAR ON LOWER RESPIRATORY TRACT SAMPLES; COLLECTED FROM ICU FROM PATIENTS WITH SUSPECTED VENTILATOR ASSOCIATED PNEUMONIACATEGORY: LESSON IN MICROBIOLOGY & INFECTION CONTROL. Journal of Infection vol. 63, (6) E22-E23. 10.1016/j.jinf.2011.04.051
Soleimanian S, Gordon NC and Wareham DW (2011). Polymicrobial necrotizing fasciitis involving enterobacteria producing CTX-M-15 extended-spectrum β-lactamases. J Med Microbiol vol. 60, (Pt 1) 135-137. 10.1099/jmm.0.021998-0
Wareham DW, Gordon NC and Shimizu K (2011). Two new variants of and creation of a repository for Stenotrophomonas maltophilia quinolone protection protein (Smqnr) genes. Int J Antimicrob Agents vol. 37, (1) 89-90. 10.1016/j.ijantimicag.2010.10.002
2010
Gordon NC, Png K and Wareham DW (2010). Potent synergy and sustained bactericidal activity of a vancomycin-colistin combination versus multidrug-resistant strains of Acinetobacter baumannii. Antimicrob Agents Chemother vol. 54, (12) 5316-5322. 10.1128/AAC.00922-10
Wareham DW, Umoren I, Khanna P and Gordon NC (2010). Allele-specific polymerase chain reaction (PCR) for rapid detection of the aac(6')-Ib-cr quinolone resistance gene. Int J Antimicrob Agents vol. 36, (5) 476-477. 10.1016/j.ijantimicag.2010.07.012
Gordon NC and Wareham DW (2010). Antimicrobial activity of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia. Int J Antimicrob Agents vol. 36, (2) 129-131. 10.1016/j.ijantimicag.2010.03.025
Hornsey M, Ellington MJ, Doumith M, Thomas CP, Gordon NC, Wareham DW, Quinn J, Lolans K, Livermore DM and Woodford N (2010). AdeABC-mediated efflux and tigecycline MICs for epidemic clones of Acinetobacter baumannii. J Antimicrob Chemother vol. 65, (8) 1589-1593. 10.1093/jac/dkq218
Hall TJ, Wren MW, Wareham DW, Jeanes A and Gant VA (2010). Effect of the dried residues of two hand gels on the survival of meticillin-resistant staphylococcus aureus and acinetobacter calcoaceticus-baumannii. Journal of Infection Prevention vol. 11, (3) 70-72. 10.1177/1757177410365579
Gordon NC and Wareham DW (2010). Novel variants of the Smqnr family of quinolone resistance genes in clinical isolates of Stenotrophomonas maltophilia. J Antimicrob Chemother vol. 65, (3) 483-489. 10.1093/jac/dkp476
Jozsef S, Wareham DW, Ratkai C, Aduse-Opoku J, Urban E and Elisabeth N (2010). Prevalence, nucleotide sequence and expression studies of two proteins of a 5.6 kb, Class III, Bacteroides plasmid frequently found in clinical isolates from European countries. Plasmid vol. 63, (2) 86-97. 10.1016/j.plasmid.2009.12.002
Gordon NC and Wareham DW (2010). Multidrug-resistant Acinetobacter baumannii: mechanisms of virulence and resistance. Int J Antimicrob Agents vol. 35, (3) 219-226. 10.1016/j.ijantimicag.2009.10.024
Wareham D and Bean D (2010). Molecular typing of multi-drug resistant Acinetobacter baumannii from London hospitals. Int J Infect Dis vol. 14, E36-E36. 10.1016/j.ijid.2010.02.1566
Wareham D and Bean D (2010). Nebulised colistin for nosocomial Acinetobacter baumannii respiratory tract infection. Cochrane Database of Systematic Reviews Wiley 10.1002/14651858.cd006820.pub2
Millar M and Wareham D (2010). Infections associated with implanted medical devices. Antibiotic and Chemotherapy: Expert Consult 10.1016/B978-0-7020-4064-1.00042-7
2009
Amin AK and Wareham DW (2009). Plasmid-mediated quinolone resistance genes in Enterobacteriaceae isolates associated with community and nosocomial urinary tract infection in East London, UK. Int J Antimicrob Agents vol. 34, (5) 490-491. 10.1016/j.ijantimicag.2009.01.003
Gordon NC and Wareham DW (2009). Failure of the MicroScan WalkAway system to detect heteroresistance to carbapenems in a patient with Enterobacter aerogenes bacteremia. J Clin Microbiol vol. 47, (9) 3024-3025. 10.1128/JCM.01033-09
Gordon NC and Wareham DW (2009). Evaluation of CHROMagar Acinetobacter for detection of enteric carriage of multidrug-resistant Acinetobacter baumannii in samples from critically ill patients. J Clin Microbiol vol. 47, (7) 2249-2251. 10.1128/JCM.00634-09
Wareham DW, Gordon NC, Casals JB and Bean DC (2009). Reduced susceptibility of multidrug-resistant Acinetobacter baumannii to tigecycline in combination with 1-(1-naphthylmethyl)-piperazine is not a pH-dependent phenomenon. J Antimicrob Chemoth vol. 63, (5) 1075-1076. 10.1093/jac/dkp072
Amin AK, O'Connor I, Lavin K and Wareham DW (2009). Prevention of an outbreak of nosocomial bloodstream infection associated with a new vascular access device by retraining of staff. J Hosp Infect vol. 72, (1) 85-87. 10.1016/j.jhin.2009.01.017
Soleimanian S and Wareham DW (2009). Pancreatitis, Diarrhea, and Glycopeptide Dependence. Wolters Kluwer Infectious Diseases in Clinical Practice vol. 17, (3) 206-207. 10.1097/ipc.0b013e31818718fd
Gordon NC and Wareham DW (2009). A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline. J Antimicrob Chemother vol. 63, (4) 775-780. 10.1093/jac/dkn555
Woodford N, Wareham DW and UK Antibacterial Antisense Study Group (2009). Tackling antibiotic resistance: a dose of common antisense? J Antimicrob Chemother vol. 63, (2) 225-229. 10.1093/jac/dkn467
Bean DC and Wareham DW (2009). Paradoxical effect of 1-(1-naphthylmethyl)-piperazine on resistance to tetracyclines in multidrug-resistant Acinetobacter baumannii. J Antimicrob Chemother vol. 63, (2) 349-352. 10.1093/jac/dkn493
Shah A, Gordon N, Pheel L and Wareham D (2009). Comparison of microscopic, phenotypic and molecular techniques for the rapid identification and susceptibility testing of Staphylococci from positive blood culture bottles. Springer Nature Critical Care vol. 13, (Suppl 4) 10.1186/cc8100
2008
Wareham DW, Bean DC, Khanna P, Hennessy EM, Krahe D, Ely A and Millar M (2008). Bloodstream infection due to Acinetobacter spp: epidemiology, risk factors and impact of multi-drug resistance. Eur J Clin Microbiol Infect Dis vol. 27, (7) 607-612. 10.1007/s10096-008-0473-y
Bean DC, Krahe D and Wareham DW (2008). Antimicrobial resistance in community and nosocomial Escherichia coli urinary tract isolates, London 2005-2006. Ann Clin Microbiol Antimicrob vol. 7, 10.1186/1476-0711-7-13
Khanna P, Doffman S, Griffiths L, Wareham D, Agrawal SG and Das S (2008). A case of febrile nelitropenia with a skin rash. J Infection vol. 56, (4) 309-309. 10.1016/j.jinf.2008.01.040
2007
Wareham D and Bean D (2007). Nebulised colistin for nosocomial Acinetobacter baumannii respiratory tract infection. Cochrane Database of Systematic Reviews (4) 10.1002/14651858.CD006820
Edwards J, Patel G and Wareham DW (2007). Low concentrations of commercial alcohol hand rubs facilitate growth of and secretion of extracellular proteins by multidrug-resistant strains of Acinetobacter baumannii. J Med Microbiol vol. 56, (Pt 12) 1595-1599. 10.1099/jmm.0.47442-0
Khanna P, Wareham DW, Bean DC and Krahé D (2007). Microbiological surveillance of gram-negative bactaeremia in the intensive care unit: a teaching hospital experience. Elsevier Journal of Infection vol. 55, (3) 10.1016/j.jinf.2007.04.133
Wareham DW and Curtis MA (2007). A genotypic and phenotypic comparison of type III secretion profiles of Pseudomonas aeruginosa cystic fibrosis and bacteremia isolates. Int J Med Microbiol vol. 297, (4) 227-234. 10.1016/j.ijmm.2007.02.004
Wareham DW and Breuer J (2007). Herpes zoster. Bmj vol. 334, (7605) 1211-1215. 10.1136/bmj.39206.571042.AE
Michael JS, Wareham DW, El-Karim A, Warwick S, Millar M and Das SS (2007). Evaluation of 16SrDNA PCR and sequencing for the diagnosis of infective endocarditis. Clin Res Cardiol vol. 96, (6) 411-412.
Wareham DW, Michael JS, Warwick S, Whitlock P, Wood A and Das SS (2007). The dangers of dog bites. J Clin Pathol vol. 60, (3) 328-329. 10.1136/jcp.2006.037671
Michael JS, Das SS and Wareham DW (2007). The Dangers of Dog Bites. Elsevier Journal of Infection vol. 54, (3) 10.1016/j.jinf.2006.10.012
Pumbwe L, Wareham DW, Aduse-Opoku J, Brazier JS and Wexler HM (2007). Genetic analysis of mechanisms of multidrug resistance in a clinical isolate of Bacteroides fragilis. Clin Microbiol Infect vol. 13, (2) 183-189. 10.1111/j.1469-0691.2006.01620.x
2006
Cepeda JA, Millar M, Sheridan EA, Warwick S, Raftery M, Bean DC and Wareham DW (2006). Listeriosis due to infection with a catalase-negative strain of Listeria monocytogenes. J Clin Microbiol vol. 44, (5) 1917-1918. 10.1128/JCM.44.5.1917-1918.2006
Wareham DW and Bean DC (2006). In-vitro activity of polymyxin B in combination with imipenem, rifampicin and azithromycin versus multidrug resistant strains of Acinetobacter baumannii producing OXA-23 carbapenemases. Ann Clin Microbiol Antimicrob vol. 5, 10.1186/1476-0711-5-10
Wareham DW, Abbas H, Karcher AM and Das SS (2006). Treatment of prosthetic valve infective endocarditis due to multi-resistant Gram-positive bacteria with linezolid. J Infect vol. 52, (4) 300-304. 10.1016/j.jinf.2005.05.022
Wareham DW and Bean DC (2006). In vitro activities of polymyxin B, imipenem, and rifampin against multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother vol. 50, (2) 10.1128/AAC.50.2.825-826.2006
2005
Wareham D (2005). Postherpetic neuralgia. Clin Evid (14) 1017-1025.
Wareham DW, Wilks M, Ahmed D, Brazier JS and Millar M (2005). Anaerobic sepsis due to multidrug-resistant Bacteroides fragilis: microbiological cure and clinical response with linezolid therapy. Clin Infect Dis vol. 40, (7) e67-e68. 10.1086/428623
Wareham DW, Papakonstantinopoulou A and Curtis MA (2005). The Pseudomonas aeruginosa PA14 type III secretion system is expressed but not essential to virulence in the Caenorhabditis elegans-P. aeruginosa pathogenicity model. Fems Microbiol Lett vol. 242, (2) 209-216. 10.1016/j.femsle.2004.11.018
WAREHAM DW, Das S and Michael J (2005). Advances in bacterial specific imaging. Brazilian Archives of Biology and Technology vol. 48, 145-152. 10.1590/S1516-89132005000700021
WAREHAM DW, Das SS, Abbas H and Karcher AM (2005). Treatment of infective endocarditis due to multiresistant Gram-positive bacteria with linezolid. J Infect 10.1016/j.jinf.2005.05.022
2004
Wareham D (2004). Postherpetic neuralgia. Clin Evid (12) 1182-1193.
2003
Wareham D (2003). Postherpetic neuralgia. Clin Evid (10) 942-952.
Lancaster T, Wareham D and Yaphe J (2003). Postherpetic neuralgia. Clinical Evidence (9) 890-900.
Lancaster T, Wareham DW and Yaphe J (2003). Postherpetic neuralgia. Am Fam Physician vol. 67, (7) 1557-1558.
Das SS, Britton KE, Solanki KK and Wareham DW (2003). (99m)Tc-ciprofloxacin scintigraphy in rabbit model of prosthetic joint infection. J Nucl Med vol. 44, (2) 317-319.
2002
Britton KE, Wareham DW, Das SS, Solanki KK, Amaral H, Bhatnagar A, Katamihardja AHS, Malamitsi J, Moustafa HM, Soroa VE, Sundram FX and Padhy AK (2002). Imaging bacterial infection with (99m)Tc-ciprofloxacin (Infecton). J Clin Pathol vol. 55, (11) 817-823. 10.1136/jcp.55.11.817
Das SS, Wareham DW and Britton KE (2002). 99mTc-labeled antimicrobial peptides for detection of bacterial and Candida albicans infections. J Nucl Med vol. 43, (8)
Lancaster T, Wareham D and Yaphe J (2002). Postherpetic neuralgia. Clinical Evidence (7) 738-746.
Wareham DW and Wilson P (2002). Chloramphenicol in the 21st century. Hosp Med vol. 63, (3) 157-161. 10.12968/hosp.2002.63.3.2061
BRITTON KE, Soroa VE, Das SS, Sundram FX, Padhy AK, Wareham DW, Solanki KK, Moustafa HM, Katamihardja AH, Bhatnagar A, Amaral H and Malamitsi J (2002). Imaging bacterial infection with (99m)Tc-Ciprofloxacin (Infecton). J Clin Pathol. vol. 55, 817-823. 10.1136/jcp.55.11.817
2001
Wareham DW, Döring G and Vochem M (2001). Sepsis in a newborn due to Pseudomas aeruginosa from a contaminated tub bath [4] (multiple letters). New England Journal of Medicine vol. 345, (22) 1644-1645. 10.1056/NEJM200111293452214
Wareham DW (2001). Sepsis in a newborn due to Pseudomonas aeruginosa from a contaminated tub bath. N Engl J Med vol. 345, (22) 1644-1645. 10.1056/nejm200111293452215
Britton KE, Wareham DW and Das SS (2001). Concerns about 99mTc-labelled ciprofloxacin for infection detection. Eur J Nucl Med vol. 28, (6) 779-781. 10.1007/s002590100520
Wareham DW, Breuer J, Healy MT and Goldhill DR (2001). Pneumonitis in an elderly Bangladeshi man. J Clin Pathol vol. 54, (6) 10.1136/jcp.54.6.494
BRITTON KE, Das SS and Wareham DW (2001). Concerns about 99mTc-labelledCiprofloxacin for infection detection. Eur J Nucl Med. vol. 28, 779-781. 10.1007/s002590100520
Breuer J and WAREHAM DW (2001). Primary varicella infection presenting in old age. Grand Rounds vol. 1, 3-4.
2000
Wareham DW and Breuer J (2000). Management of occupational exposure to hepatitis C: survey of United Kingdom practice. Communicable Disease and Public Health vol. 3, (4) 295-296.
Britton KE, Wareham D, Solanki KK and Das SS (2000). Imaging of bacterial infections with Tc-99m-labeled human neutrophil peptide-1. J Nucl Med vol. 41, (12) 2099-2100.
Das SS, Britton KE, Solanki KK and Wareham DW (2000). Technetium-99m labelled antimicrobial peptides discriminate between bacterial infections and sterile inflammations. Springer Nature European Journal of Nuclear Medicine and Molecular Imaging vol. 27, (12) 1865-1866. 10.1007/s002590000377
Britton KE, Solanki KK, Das SS, Amaral H, Bhatnagar A, Katamihardja AH, Malamitsi J, Moustafa H, Soroa VE, Sundram FX, Wareham DW and Padhy AK (2000). Bacterial specific imaging. Journal of Nuclear Medicine vol. 41, (5) 11P-11P.
Grants
Comparative Activity of Tedizolid versus Glycopeptide Combination Therapies for the Treatment of Staphylococcus aureus Infections:An in vitro and in vivo Evaluation against Strains with Reduced Susceptibility to Glycopeptides
Wareham DW
£36,699 Merck & Co., Inc. (27-05-2015 - 27-05-2016)
Wareham DW
£36,699 Merck & Co., Inc. (27-05-2015 - 27-05-2016)