Dr Carles Gaston-Massuet

Carles Gaston-Massuet

Senior Lecturer in Endocrine Genetics

Center of Enodcrinology, William Harvey Research Institute
Queen Mary University of London
07813 785064

Research

Endocrinology, Hypothalamus-pituitary axis, genetics, development, tumour biology, endocrine system

Interests

Genetics and molecular mechanisms underlying the hypothalmo-pituitary axis development and its link to disease from endocrine deficiencies to tumorigenesis.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2025

Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma
Mariniello K, Pittaway JFH, Altieri B, Borges KS, Hadjidemetriou I, Ribeiro C, Ruiz‐Babot G, Tourigny DS et al.
Cancer Communications, Wiley vol. 45 (6), 663-668.  
04-03-2025

2024

Senescent endothelial cells promote pathogenic neutrophil trafficking in inflamed tissues
Rolas L, Stein M, Barkaway A, Reglero-Real N, Sciacca E, Yaseen M, Wang H, Vazquez-Martinez L et al.
Embo Reports, Springer Nature vol. 25 (9), 3842-3869.  
25-06-2024

2023

Correction: RET signalling provides tumorigenic mechanism and tissue specificity for AIP-related somatotrophinomas
Garcia-Rendueles AR, Chenlo M, Oroz-Gonjar F, Solomou A, Mistry A, Barry S, Gaston-Massuet C, Garcia-Lavandeira M et al.
Oncogene, Springer Nature vol. 42 (49), 3655-3656.  
06-11-2023
Imprinted Dlk1 dosage as a size determinant of the mammalian pituitary gland
Scagliotti V, Vignola ML, Willis T, Howard M, Marinelli E, Gaston-Massuet C, Andoniadou C, Charalambous M
Elife, Elife vol. 12 
17-08-2023
Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.
Escuin S, Rose Raza-Knight S, Savery D, Gaston-Massuet C, Galea GL, Greene NDE, Copp AJ
Disease Models & Mechanisms vol. 16 (3) 
01-03-2023

2022

Phosphorylation of β-catenin at Serine552 correlates with invasion and recurrence of non-functioning pituitary neuroendocrine tumours
Rai A, Yelamanchi SD, Radotra BD, Gupta SK, Mukherjee KK, Tripathi M, Chhabra R, Ahuja CK et al.
Acta Neuropathologica Communications, Springer Nature vol. 10 (1) 
16-09-2022
The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates
Glaser J, Iranzo J, Borensztein M, Marinucci M, Gualtieri A, Jouhanneau C, Teissandier A, Gaston-Massuet C et al.
Elife, Elife vol. 11 
20-01-2022

2021

Hyper-phosphorylation of [beta]-catenin at Serine552 correlates with invasion and predicts recurrence of Non-Functioning Pituitary Tumours (NFPTs)
Rai A, Yelamanchi SD, Radotra BD, Gupta SK, Chhabra R, Pandey A, Korbonits M, Gaston-Massuet C et al.
BES2021. 
18-10-2021
RET signalling provides tumorigenic mechanism and tissue specificity for AIP-related somatotrophinomas
Garcia-Rendueles AR, Chenlo M, Oroz-Gonjar F, Solomou A, Mistry A, Barry S, Gaston-Massuet C, Garcia-Lavandeira M et al.
Oncogene, Springer Nature vol. 40 (45), 6354-6368.  
29-09-2021
Dysgenesis and Dysfunction of the Pancreas and Pituitary Due to FOXA2 Gene Defects
Kaygusuz SB, Ates EA, Vignola ML, Volkan B, Geckinli BB, Turan S, Bereket A, Gaston-Massuet C et al.
The Journal of Clinical Endocrinology & Metabolism, The Endocrine Society vol. 106 (10), e4142-e4154.  
17-05-2021
FOXA2 as a Candidate Gene Responsible for Congenital Panhypopituitarism: A Review of the Literature
Correia JC, Corral LG, Kaygusuz SB, Gualtieri A, Gaston-Massuet C
Journal of The Endocrine Society, The Endocrine Society vol. 5 (Supplement_1), a529-a529.  
03-05-2021
WNT3A‐loaded exosomes enable cartilage repair
Thomas BL, Eldridge SE, Nosrati B, Alvarez M, Thorup A, Nalesso G, Caxaria S, Barawi A et al.
Journal of Extracellular Vesicles, Wiley vol. 10 (7) 
01-05-2021
Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans

Nature Communications, Springer Nature vol. 12 (1) 
01-04-2021
Novel LZTR1 mutations in subjects with features of Noonan Syndrome and GH insensitivity negatively regulate GH-induced IGF-I production and hyperactivate GH-induced ERK1/2 activation in response to GH in vitro
Chatterjee S, Bertola DR, Agwu C, Maharaj A, Williams J, Cottrell E, Shapiro L, Andrews A et al.
 
01-01-2021

2020

Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin
Crescente M, Armstrong PC, Kirkby NS, Edin ML, Chan MV, Lih FB, Jiao J, Maffucci T et al.
The Faseb Journal, Wiley Periodicals Llc 
27-06-2020
A Novel SEMA3G Mutation in Two Siblings Affected by Syndromic GnRH Deficiency
Oleari R, André V, Lettieri A, Tahir S, Roth L, Paganoni A, Eberini I, Parravicini C et al.
Neuroendocrinology, Karger Publishers vol. 111 (5), 421-441.  
04-05-2020

2019

A novel clinical risk score that accurately predicts recurrence of craniopharyngioma - a multicentre cohort study
Kyprianou N, Blackburn J, Tan R, Korbonits M, Dattani M, Dutta P, Bhansali A, Rai A et al.
Endocrine Abstracts, Bioscientifica 
11-11-2019
Stem Cells, Self-Renewal, and Lineage Commitment in the Endocrine System
Mariniello K, Ruiz-Babot G, McGaugh EC, Nicholson JG, Gualtieri A, Gaston-Massuet C, Nostro MC, Guasti L
Frontiers in Endocrinology, Frontiers vol. 10 
08-11-2019
Transcriptomic analyses reveal deregulation of focal adhesion pathway in Aip KO mice and AIP mutation positive human tumours
Bollington M, Mistry A, Solomou A, Barry S, Begalli F, Vignola M, Lim CT, Herincs M et al.
Endocrine Abstracts, Bioscientifica 
06-11-2019
Investigating the role of AIP in pituitary tumourigenesis
Mistry A, Solomou A, Vignola ML, Lim CT, Herincs M, Caimari F, Costa AI, Begalli F et al.
Endocrine Abstracts, Bioscientifica 
06-11-2019
Cell-Specific Gene Deletion Reveals the Antithrombotic Function of COX1 and Explains the Vascular COX1/Prostacyclin Paradox
Mitchell JA, Shala F, Elghazouli Y, Warner TD, Gaston-Massuet C, Crescente M, Armstrong PC, Herschman HR et al.
Circulation Research, American Heart Association vol. 125 (9), 847-854.  
12-09-2019
Pathogenic variants in PLOD3 result in a Stickler syndrome-like connective tissue disorder with vascular complications
Ewans LJ, Colley A, Gaston-Massuet C, Gualtieri A, Cowley MJ, McCabe MJ, Anand D, Lachke SA et al.
Journal of Medical Genetics, Bmj vol. 56 (9) 
25-05-2019
Constitutive Activation of β-Catenin in Conventional Dendritic Cells Increases the Insulin Reserve to Ameliorate the Development of Type 2 Diabetes in Mice
Macdougall CE, Wood EG, Solomou A, Scagliotti V, Taketo MM, Gaston-Massuet C, Marelli-Berg FM, Charalambous M et al.
Diabetes, American Diabetes Association vol. 68 (7), 1473-1484.  
02-05-2019
Impaired EIF2S3 function associated with a novel phenotype of X-linked hypopituitarism with glucose dysregulation
Gregory LC, Ferreira CB, Young-Baird SK, Williams HJ, Harakalova M, van Haaften G, Rahman SA, Gaston-Massuet C et al.
Ebiomedicine, Elsevier vol. 42, 470-480.  
14-03-2019
Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors
Barry S, Carlsen E, Marques P, Stiles CE, Gadaleta E, Berney DM, Roncaroli F, Chelala C et al.
Oncogene, Springer Nature vol. 38 (27), 5381-5395.  
12-03-2019

2018

Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets
Macdougall CE, Wood EG, Loschko J, Scagliotti V, Cassidy FC, Robinson ME, Feldhahn N, Castellano L et al.
Cell Metabolism, Elsevier vol. 27 (3), 588-601.e4.  
01-03-2018
Rings and Bricks: Expression of Cohesin Components is Dynamic during Development and Adult Life
Bettini LR, Graziola F, Fazio G, Grazioli P, Scagliotti V, Pasquini M, Cazzaniga G, Biondi A et al.
International Journal of Molecular Sciences, Mdpi vol. 19 (2) 
01-02-2018
Investigating β-catenin signalling in conventional dendritic cells in obesity-induced tissue inflammation
Macdougall C, Wood E, Charalambous M, Gaston-Massuet C, Taketo MM, Marelli-Berg F, Longhi MP
 
01-01-2018

2017

The MAPK effector B-Raf is essential for hypothalamic-pituitary axis development and activating mutations in BRAF Cause Congenital hypopituitarism

Endocrine Abstracts, Bioscientifica 
30-10-2017
Novel FOXA2 mutation causes hyperinsulinism, hypopituitarism with craniofacial dysmorphism and endoderm-derived organ abnormalities
Giri D, Vignola ML, Gualtieri A, Scagliotti V, McNamara P, Peak M, Didi M, Gaston-Massuet C et al.
Endocrine Abstracts, Bioscientifica 
30-10-2017
A comprehensive analysis of the AIP mutation positive pituitary tumour microenvironment: role of stromal cells and the pro-inflammatory cytokine network
Barry S, Solomou A, Vignola L, Collier D, Carlsen E, Gadaleta E, Berney DM, Chelala C et al.
Endocrine Abstracts, Bioscientifica 
20-10-2017
Cyclooxygenase-2 is a potential target for the treatment of Adamantinomatous craniopharyngioma
Scagliotti V, Gutierrez LP, Gualtieri A, Jimenez F, Kirkby N, Mitchell J, Warner T, Gevers E et al.
 
20-10-2017
Investigating the role of AIP in mouse pituitary adenoma formation
Solomou A, Herincs M, Roncaroli F, Vignola ML, Gaston-Massuet C, Korbonits M
Endocrine Abstracts, Bioscientifica 
20-10-2017
The MAPK effector B-Raf is essential for hypothalamic-pituitary axis development and activating mutations in BRAF cause congenital hypopituitarism
Kyprianou N, Gregory L, Lillina VM, Besser R, Marinelli E, Gualtieri A, Scagliotti V, Davis S et al.
Endocrine Abstracts, Bioscientifica 
20-10-2017
Novel FOXA2 mutation causes Hyperinsulinism, Hypopituitarism with Craniofacial and Endoderm-derived organ abnormalities
Giri D, Vignola ML, Gualtieri A, Scagliotti V, McNamara P, Peak M, Didi M, Gaston-Massuet C et al.
Human Molecular Genetics, Oxford University Press (Oup) vol. 26 (22), 4315-4326.  
24-08-2017
Ephrin-B2 is critical regulator of endocrine organ development
Jimenez FA, Gualtieri A, Scagliotti V, Gaston-Massuet C
 
01-07-2017
PLATELET COX-1 KNOCKOUT MOUSE AS A MODEL OF THE EFFECTS OF ASPIRIN IN THE CARDIOVASCULAR SYSTEM
Crescente M, Armstrong PC, CHAN MV, Edin ML, Lih FB, Jiao J, Gaston-Massuet C, Cottrell GS et al.
BCS Annual Conference, ‘Cardiology at the Extremes'. 
01-06-2017
Ephrin-B2 is required for pituitary development
Jimenez F, Gualtieri A, Scagliotti V, Gaston-Massuet C
Endocrine Abstracts, Bioscientifica 
03-05-2017
Characterization of a Novel Mouse Model of Endothelial Cell Progerin Expression
Rolas L, Barkaway A, Morrell S, Golding M, Gaston-Massuet C, Lopez-Otin C, Nourshargh S
 
01-01-2017
IDENTIFICATION OF GENETIC VARIANTS IN A LARGE COHORT OF PATIENTS WITH CONGENITAL HYPOTHALAMO-PITUITARY DISORDERS
Gregory LC, Mccabe MJ, Alatzoglou KS, Turton JP, Webb EA, Williams H, Gaston-Massuet C, Kelberman D et al.
 
01-01-2017
A NOVEL DENOVO FORKHEAD BOX A2 (FOXA2) MUTATION LEADS TO CONGENITAL HYPERINSULINISM, CRANIOFACIAL DYSMORPHIC FEATURES AND CONGENITAL HYPOPITUITARISM
Giri D, Vignola ML, Gualtieri A, Scagliotti V, Didi M, Gaston-Massuet C, Senniappan S
 
01-01-2017

2016

Transcription factor 7-like 1 is involved in hypothalamo–pituitary axis development in mice and humans
Gaston-Massuet C, McCabe MJ, Scagliotti V, Young RM, Carreno G, Gregory LC, Jayakody SA, Pozzi S et al.
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 113 (5), e548-e557.  
13-01-2016
The MAPK Effector BRAF is Essential for the Integrity of Hypothalamic-Pituitary Development and Deregulation of this Pathway Causes Congenital Hypopituitarism
Gregory L, Kypranou N, Besser R, Vignola L, Temple K, Davis J, Gevers E, Dattani M et al.
 
01-01-2016
A Novel Mutation in Eukaryotic Translation Initiation Factor 2 Subunit 3 (EIF2S3) is Associated with X-Linked Hypopituitarism and Glucose Dysregulation
Gregory LC, Williams H, Rahman S, Ferreira CB, Alatzoglou KS, Kapoor RR, Hussain K, Gaston-Massuet C et al.
 
01-01-2016

2015

Cell death and cell proliferation in human spina bifida
Avagliano L, Doi P, Tosi D, Scagliotti V, Gualtieri A, Gaston-Massuet C, Pistocchi A, Gallina A et al.
Birth Defects Research Part a Clinical and Molecular Teratology, Wiley vol. 106 (2), 104-113.  
10-12-2015
CyclinD1 Down‐Regulation and Increased Apoptosis Are Common Features of Cohesinopathies
Fazio G, Gaston-Massuet C, Bettini LR, Graziola F, Scagliotti V, Cereda A, Ferrari L, Mazzola M et al.
Journal of Cellular Physiology, Wiley vol. 231 (3), 613-622.  
23-11-2015
Novel application of luciferase assay for the in vitro functional assessment of KAL1 variants in three females with septo-optic dysplasia (SOD)
McCabe MJ, Hu Y, Gregory LC, Gaston-Massuet C, Alatzoglou KS, Saldanha JW, Gualtieri A, Thankamony A et al.
Molecular and Cellular Endocrinology, Elsevier vol. 417, 63-72.  
14-09-2015
Histopathology and molecular characterisation of intrauterine-diagnosed congenital craniopharyngioma
Scagliotti V, Avagliano L, Gualtieri A, Graziola F, Doi P, Chalker J, Righini A, Korbonits M et al.
Pituitary, Springer Nature vol. 19 (1), 50-56.  
09-09-2015
The role of the sonic hedgehog signalling pathway in patients with midline defects and congenital hypopituitarism.
Gregory LC, Gaston-Massuet C, Andoniadou CL, Carreno G, Webb EA, Kelberman D, McCabe MJ, Panagiotakopoulos L et al.
Clin Endocrinol (Oxf) vol. 82 (5), 728-738.  
01-05-2015

2014

Pituitary and Neuroendocrinology
Gevers EF, Gaston-Massuet C, de Roux N
In Yearbook of Pediatric Endocrinology 2014, Karger Publishers 1-14.  
01-08-2014

2013

Sox2(+) stem/progenitor cells in the adult mouse pituitary support organ homeostasis and have tumor-inducing potential.
Andoniadou CL, Matsushima D, Mousavy Gharavy SN, Signore M, Mackintosh AI, Schaeffer M, Gaston-Massuet C, Mollard P et al.
Cell Stem Cell vol. 13 (4), 433-445.  
03-10-2013
Pituitary
Gevers EF, Gaston-Massuet C, Dattani MT
In Yearbook of Pediatric Endocrinology 2013, Karger Publishers 13-30.  
01-09-2013
Variations in PROKR2, but not PROK2, are associated with hypopituitarism and septo-optic dysplasia.
McCabe MJ, Gaston-Massuet C, Gregory LC, Alatzoglou KS, Tziaferi V, Sbai O, Rondard P, Masumoto K-H et al.
J Clin Endocrinol Metab vol. 98 (3), E547-E557.  
01-03-2013
Nipbl expression analysis in the developing mouse embryo
Graziola F, Scagliotti V, Gold-Diaz D, Gaston-Massuet C, Massa V
 
01-01-2013

2012

SOX2 regulates the hypothalamic-pituitary axis at multiple levels.
Jayakody SA, Andoniadou CL, Gaston-Massuet C, Signore M, Cariboni A, Bouloux PM, Le Tissier P, Pevny LH et al.
J Clin Invest vol. 122 (10), 3635-3646.  
01-10-2012
Pituitary
Gevers EF, Gaston-Massuet C, Dattani MT
In Yearbook of Pediatric Endocrinology 2012, Karger Publishers 13-28.  
11-09-2012
Identification of novel pathways involved in the pathogenesis of human adamantinomatous craniopharyngioma.
Andoniadou CL, Gaston-Massuet C, Reddy R, Schneider RP, Blasco MA, Le Tissier P, Jacques TS, Pevny LH et al.
Acta Neuropathol vol. 124 (2), 259-271.  
01-08-2012

2011

HESX1- and TCF3-mediated repression of Wnt/β-catenin targets is required for normal development of the anterior forebrain.
Andoniadou CL, Signore M, Young RM, Gaston-Massuet C, Wilson SW, Fuchs E, Martinez-Barbera JP
Development vol. 138 (22), 4931-4942.  
01-11-2011
Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunction.
McCabe MJ, Gaston-Massuet C, Tziaferi V, Gregory LC, Alatzoglou KS, Signore M, Puelles E, Gerrelli D et al.
J Clin Endocrinol Metab vol. 96 (10), E1709-E1718.  
01-10-2011
Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans.
GASTON MASSUET JC, Andoniadou CL, Signore M, Jayakody SA, Charolidi N, Kyeyune R, Vernay B, Jacques TS et al.
Proc Natl Acad Sci U S a. vol. 108 (28), 11482-11487.  
01-01-2011
Investigating genetic factors underlying hypopituitarism and septo-optic dysplasia in humans
Jayakody SA, Andoniadou C, Signore M, Gaston-Massuet C, Pevny LH, Brue T, Martinez-Barbera J-P
 
01-01-2011

2010

Enhancement of the Canonical Wnt Pathway in Rathke's Pouch Results in Pituitary Tumours Reminiscent of Human Adamantinomatous Craniopharyngioma
Gaston-Massuet C, Andoniadou CL, Signore M, Jayakody S, Charolidi N, Le Tissier P, Dattani M, Martinez-Barbera JP
 
01-01-2010
ASPP2 Binds Par-3 and Controls the Polarity and Proliferation of Neural Progenitors during CNS Development
Sottocornola R, Royer C, Vives V, Tordella L, Zhong S, Wang Y, Ratnayaka I, Shipman M et al.
Developmental Cell vol. 19 (1), 126-137.  
01-01-2010

2009

Absence of SIX3 mutations in patients with congenital hypopituitarism.
Gaston-Massuet C, Kelberman D, Dattani M, Martinez-Barbera JP
Am J Med Genet A vol. 149A (12), 2874-2876.  
01-12-2009
Abstracts of papers presented at the nineteenth Genetics Society's Mammalian Genetics and Development Workshop held at the Institute of Child Health, University College London on 20 and 21 November 2008
GREENE NDE, COPP AJ, PAUWS E, STANIER P, PHILPOTT A, BROS V, FLENNIKEN A, SCHIAVO G et al.
Genetics Research, Hindawi vol. 91 (2), 133-141.  
01-04-2009
Hesx1 antagonises canonical Wnt signalling in anterior forebrain and pituitary gland
Andoniadou CL, Gaston-Massuet C, Martinez-Barbera JP
 
01-01-2009
Molecular analysis of Hesx1 function in pituitary and hypothalamic development
Jayakody SA, Gaston-Massuet C, Andoniadou CL, Dattani M, Matinez-Barbera JP
 
01-01-2009
Role of Zic2 in mammalian neural tube closure
Massa V, Ybot-Gonzalez P, Savery D, Gaston-Massuet C, Greene NE, Copp AJ
Genetics Research vol. 91 (2), 140-140.  
01-01-2009

2008

Genetic interaction between the homeobox transcription factors HESX1 and SIX3 is required for normal pituitary development.
Gaston-Massuet C, Andoniadou CL, Signore M, Sajedi E, Bird S, Turner JMA, Martinez-Barbera JP
Dev Biol vol. 324 (2), 322-333.  
15-12-2008
Analysis of mouse models carrying the I26T and R160C substitutions in the transcriptional repressor HESX1 as models for septo-optic dysplasia and hypopituitarism.
Sajedi E, Gaston-Massuet C, Signore M, Andoniadou CL, Kelberman D, Castro S, Etchevers HC, Gerrelli D et al.
Dis Model Mech vol. 1 (4-5), 241-254.  
01-01-2008
DNMT1 interacts with the developmental transcriptional repressor HESX1.
Sajedi E, Gaston-Massuet C, Andoniadou CL, Signore M, Hurd PJ, Dattani M, Martinez-Barbera JP
Biochim Biophys Acta vol. 1783 (1), 131-143.  
01-01-2008

2007

Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling.
Ybot-Gonzalez P, Gaston-Massuet C, Girdler G, Klingensmith J, Arkell R, Greene NDE, Copp AJ
Development vol. 134 (17), 3203-3211.  
01-09-2007
Abstracts of papers presented at the seventeenth Genetics Society's Mammalian Genetics and Development Workshop held at the Institute of Child Health, University College London on 9 and 10 November 2006
ROMIO L, CASTRO S, LOPES C, HAMES R, FEATHER SA, FRY AM, WILSON SW, WOOLF AS et al.
Genetics Research, Hindawi vol. 89 (3), 181-188.  
01-06-2007
Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain.
Andoniadou CL, Signore M, Sajedi E, Gaston-Massuet C, Kelberman D, Burns AJ, Itasaki N, Dattani M et al.
Development vol. 134 (8), 1499-1508.  
01-04-2007
Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain
Andoniadou C, Signore M, Sajedi E, Gaston-Massuet C, Barbera JPM
 
01-01-2007

2006

Role of the homeobox gene Hesx1/HESX1 in forebrain and pituitary formation in mouse and humans
Sajed E, Gaston-Massuet C, Signore M, Dattani M, Martinez-Barbera JP
 
01-01-2006

2005

Zic4, a zinc-finger transcription factor, is expressed in the developing mouse nervous system.
Gaston-Massuet C, Henderson DJ, Greene NDE, Copp AJ
Dev Dyn vol. 233 (3), 1110-1115.  
01-07-2005

2003

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse.
Murdoch JN, Henderson DJ, Doudney K, Gaston-Massuet C, Phillips HM, Paternotte C, Arkell R, Stanier P et al.
Hum Mol Genet vol. 12 (2), 87-98.  
15-01-2003
Requirement for Zic2 during mouse neurulation.
Gaston-Massuet C, Elms P, Henderson D, Arkell R, Copp A
 
01-01-2003

Grants

solid heart iconGrants of specific relevance to Predictive in vitro Models
bullet iconNeurodevelopmental disorder gene pathways in syndromic intellectual disability and hypogonadism
Sasha Howard and Carles Gaston-Massuet
£140,412 Rosetrees Trust
08-01-2024 - 07-01-2027
bullet iconUnderstanding the role of cellular senescence in RASopathies
Carles Gaston-Massuet
£249,918 SPARKS Charity
01-09-2023 - 31-08-2027
bullet iconCharacterisation and identification of novel genetic determinants of craniopharyngiomas
Carles Gaston-Massuet
£405,010 Barts and the London Charity
01-09-2020 - 01-04-2026

bullet iconThe contribution of capsular and subcapsular progenitor cells in homeostatic adrenal cortex self-renewal and zonal-specific remodelling
Leonardo Guasti, Emanuel Rognoni and Carles Gaston-Massuet
£470,140 BBSRC Biotechnology and Biological Sciences Research Council
01-11-2021 - 31-10-2024
bullet iconCharacterisation of novel genetic determinants of Craniopharyngioma tumours
Carles Gaston-Massuet and James Blackburn
£314,195 MRC Medical Research Council
03-03-2020 - 02-08-2023
bullet iconUnderstanding the oncogenic mediated pro-inflammatory environment in stem cell driven hypothalamic pituitary tumours
Carles Gaston-Massuet and Rachael Kearns
£282,039 MRC Medical Research Council
04-10-2017 - 04-08-2023
bullet iconDTP 2015
Carles Gaston-Massuet
£37,648 Medical Research Council
01-10-2016 - 30-09-2018
bullet iconMolecular Characterisation assesment of potential biomarkers and novel drug targets for childhood craniopharyngioma
Carles Gaston-Massuet
£71,591 Children with Cancer UK
01-10-2014 - 12-01-2019