Close

We use cookies to improve your experience of our website. Privacy Policy

Skip to main content
Menu

Dr Sheetal Inamdar

Sheetal Inamdar

Post Doc Researcher

School of Engineering and Material Sciences
Queen Mary University of London

Research

Cartilage biomechanics, SAXS, Collagen, Multi-scale modelling, Nanomechanics

Interests

I am interested in the age related mechanisms that lead to altered tissue structure and mechanics through nanomechanical changes in the collagen matrix. We utilise bovine cartilage to model targeted structural changes which are then probed using small angle X-ray diffraction combined with in-situ mechanics.

Publications of specific relevance to Predictive in vitro Models

Publications

2019

Inamdar SR, Barbieri E, Terrill NJ, Knight MM and Gupta HS (2019). Proteoglycan degradation mimics static compression by altering the natural gradients in fibrillar organisation in cartilage. Elsevier  Acta Biomaterialia  vol. 97, 437-450. 10.1016/j.actbio.2019.07.055

2017

Inamdar SR, Knight DP, Terrill NJ, Karunaratne A, Cacho-Nerin F, Knight MM and Gupta HS (2017). The Secret Life of Collagen: Temporal Changes in Nanoscale Fibrillar Pre-Strain and Molecular Organization During Physiological Loading of Cartilage. Acs Nano  10.1021/acsnano.7b00563

2012

Chen J, Irianto J, Inamdar S, Pravincumar P, Lee DA, Bader DL and Knight MM (2012). Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment. Biophys J  vol. 103, (6) 1188-1197. 10.1016/j.bpj.2012.07.054