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Dr Peter McCormick

Peter McCormick

William Harvey Research Institute
School of Medicine & Dentistry, Queen Mary University of London

www.qmul.ac.uk/whri/people/academic-staff/items/mccormickpeter.html

Research

Interests

We use induced pluripotent stem cells in 2D and 3D cultures to look for early molecular signatures and mechanisms of disease onset in degenerative diseases. We also use 3D cultures of tumour cell lines to identify novel targets of metastasis and tumour growth.

Publications of specific relevance to Predictive in vitro Models

Publications

2020

Moreno-Delgado D, Puigdellívol M, Moreno E, Rodríguez-Ruiz M, Botta J, Gasperini P, Chiarlone A, Howell LA, Scarselli M, Casadó V, Cortés A, Ferré S, Guzmán M, Lluís C, Alberch J, Canela EI, Ginés S and McCormick PJ (2020). Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease. Elife  vol. 9, 10.7554/eLife.51093
Contino M and McCormick PJ (2020). Editorial: The Canonical and Non-Canonical Endocannabinoid System as a Target in Cancer and Acute and Chronic Pain. Frontiers in Pharmacology  vol. 11, 10.3389/fphar.2020.00312
Lewis R, Li J, McCormick PJ, L-H Huang C and Jeevaratnam K (2020). Is the sigma-1 receptor a potential pharmacological target for cardiac pathologies? A systematic review. Ijc Heart and Vasculature  vol. 26, 10.1016/j.ijcha.2019.100449
Botta J, Appelhans J and McCormick PJ (2020). Continuing challenges in targeting oligomeric GPCR-based drugs. 10.1016/bs.pmbts.2019.11.009

2019

Bridge T, Shaikh SA, Thomas P, Botta J, McCormick PJ and Sachdeva A (2019). Site-Specific Encoding of Photoactivity in Antibodies Enables Light-Mediated Antibody–Antigen Binding on Live Cells. Angewandte Chemie - International Edition  vol. 58, (50) 17986-17993. 10.1002/anie.201908655
Botta J, Bibic L, Killoran P, McCormick PJ and Howell LA (2019). Design and development of stapled transmembrane peptides that disrupt the activity of G-protein coupled receptor oligomers. J Biol Chem  10.1074/jbc.RA119.009160
Blasco-Benito S, Moreno E, Seijo-Vila M, Tundidor I, Andradas C, Caffarel MM, Caro-Villalobos M, Urigüen L, Diez-Alarcia R, Moreno-Bueno G, Hernández L, Manso L, Homar-Ruano P, McCormick PJ, Bibic L, Bernadó-Morales C, Arribas J, Canals M, Casadó V, Canela EI, Guzmán M, Pérez-Gómez E and Sánchez C (2019). Therapeutic targeting of HER2–CB2R heteromers in HER2-positive breast cancer. Proceedings of The National Academy of Sciences of The United States of America  vol. 116, (9) 3863-3872. 10.1073/pnas.1815034116
Blasco-Benito S, Moreno E, Seijo-Vila M, Tundidor I, Andradas C, Caffarel MM, Caro-Villalobos M, Urigüen L, Diez-Alarcia R, Moreno-Bueno G, Hernández L, Manso L, Homar-Ruano P, McCormick PJ, Bibic L, Bernadó-Morales C, Arribas J, Canals M, Casadó V, Canela EI, Guzmán M, Pérez-Gómez E and Sánchez C (2019). Erratum: Therapeutic targeting of HER2-CB2R heteromers in HER2-positive breast cancer (Proceedings of the National Academy of Sciences of the United States of America (2019) 116 (3863–3872) DOI: 10.1073/pnas.1815034116). Proceedings of The National Academy of Sciences of The United States of America  vol. 116, (13) 10.1073/pnas.1903209116

2018

Aringhieri S, Carli M, Kolachalam S, Verdesca V, Cini E, Rossi M, McCormick PJ, Corsini GU, Maggio R and Scarselli M (2018). Molecular targets of atypical antipsychotics: From mechanism of action to clinical differences. Pharmacology and Therapeutics  vol. 192, 20-41. 10.1016/j.pharmthera.2018.06.012
Navarro G, Cordomí A, Brugarolas M, Moreno E, Aguinaga D, Pérez-Benito L, Ferre S, Cortés A, Casadó V, Mallol J, Canela EI, Lluís C, Pardo L, McCormick PJ and Franco R (2018). Cross-communication between Gi and Gs in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain. Bmc Biology  vol. 16, (1) 10.1186/s12915-018-0491-x

2017

García-Cárceles J, Decara JM, Vázquez-Villa H, Rodríguez R, Codesido E, Cruces J, Brea J, Loza MI, Alén F, Botta J, McCormick PJ, Ballesteros JA, Benhamú B, Rodríguez De Fonseca F and López-Rodríguez ML (2017). A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity. Journal of Medicinal Chemistry  vol. 60, (23) 9575-9584. 10.1021/acs.jmedchem.7b00994
Sauvageau E, McCormick PJ and Lefrancois S (2017). In vivo monitoring of the recruitment and activation of AP-1 by Arf1. Scientific Reports  vol. 7, (1) 10.1038/s41598-017-07493-1
Fahradpour M, Keov P, Tognola C, Perez-Santamarina E, McCormick PJ, Ghassempour A and Gruber CW (2017). Cyclotides isolated from an ipecac root extract antagonize the corticotropin releasing factor type 1 receptor. Frontiers in Pharmacology  vol. 8, (SEP) 10.3389/fphar.2017.00616
Rodríguez-Ruiz M, Moreno E, Moreno-Delgado D, Navarro G, Mallol J, Cortés A, Lluís C, Canela EI, Casadó V, McCormick PJ and Franco R (2017). Heteroreceptor Complexes Formed by Dopamine D1, Histamine H3, and N-Methyl-D-Aspartate Glutamate Receptors as Targets to Prevent Neuronal Death in Alzheimer’s Disease. Molecular Neurobiology  vol. 54, (6) 4537-4550. 10.1007/s12035-016-9995-y
González-Vera JA, Medina RA, Martín-Fontecha M, Gonzalez A, De La Fuente T, Vázquez-Villa H, García-Cárceles J, Botta J, McCormick PJ, Benhamú B, Pardo L and López-Rodríguez ML (2017). A new serotonin 5-HT 6 receptor antagonist with procognitive activity - Importance of a halogen bond interaction to stabilize the binding. Scientific Reports  vol. 7, 10.1038/srep41293
HOWELL LA, Moreno E, Chiarlone A, Medrano M, Puigdellívol M, Bibic L, Resel E, Puente N, Casarejos MJ, Perucho J, Botta J, Suelves N, Ciruela F, Ginés S, Galve-Roperh I, Casadó V, Grandes P, Lutz B, Monory K, Canela EI, Lluís C, McCormick PJ and Guzmán M (2017). Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum. Nature Publishing Group  Neuropsychopharmacology (Nature)  10.1038/npp.2017.12
McCormick PJ and Botta J (2017). Heteromers form novel signaling complexes. Receptors  10.1007/978-3-319-60174-8_19
Hoffmann HM, Crouzin N, Moreno E, Raivio N, Fuentes S, McCormick PJ, Ortiz J and Vignes M (2017). Long-lasting impairment of mGluR5-activated intracellular pathways in the striatum after withdrawal of cocaine self-administration. International Journal of Neuropsychopharmacology  vol. 20, (1) 72-82. 10.1093/ijnp/pyw086

2016

Hernandez-Garzón E, Fernandez AM, Perez-Alvarez A, Genis L, Bascuñana P, Fernandez de la Rosa R, Delgado M, Angel Pozo M, Moreno E, McCormick PJ, Santi A, Trueba-Saiz A, Garcia-Caceres C, Tschöp MH, Araque A, Martin ED and Torres Aleman I (2016). The insulin-like growth factor I receptor regulates glucose transport by astrocytes. Glia  vol. 64, (11) 1962-1971. 10.1002/glia.23035
Busnelli M, Kleinau G, Muttenthaler M, Stoev S, Manning M, Bibic L, Howell LA, McCormick PJ, Di Lascio S, Braida D, Sala M, Rovati GE, Bellini T and Chini B (2016). Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure. Journal of Medicinal Chemistry  vol. 59, (15) 7152-7166. 10.1021/acs.jmedchem.6b00564
Navarro G, Aguinaga D, Angelats E, Medrano M, Moreno E, Mallol J, Cortés A, Canela EI, Casadó V, McCormick PJ, Lluís C and Ferré S (2016). A significant role of the truncated ghrelin receptor GHS-R1b in ghrelin-induced signaling in neurons. Journal of Biological Chemistry  vol. 291, (25) 13048-13062. 10.1074/jbc.M116.715144
Navarro G, Cordomí A, Zelman-Femiak M, Brugarolas M, Moreno E, Aguinaga D, Perez-Benito L, Cortés A, Casadó V, Mallol J, Canela EI, Lluís C, Pardo L, García-Sáez AJ, McCormick PJ and Franco R (2016). Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs. Bmc Biology  vol. 14, (1) 10.1186/s12915-016-0247-4
Scarselli M, Annibale P, McCormick PJ, Kolachalam S, Aringhieri S, Radenovic A, Corsini GU and Maggio R (2016). Revealing G-protein-coupled receptor oligomerization at the single-molecule level through a nanoscopic lens: Methods, dynamics and biological function. Febs Journal  vol. 283, (7) 1197-1217. 10.1111/febs.13577
Naval-Macabuhay I, Casanova V, Navarro G, García F, León A, Miralles L, Rovira C, Martinez-Navio JM, Gallart T, Mallol J, Gatell JM, Llúis C, Franco R, McCormick PJ and Climent N (2016). Adenosine deaminase regulates Treg expression in autologous T cell-dendritic cell cocultures from patients infected with HIV-1. Journal of Leukocyte Biology  vol. 99, (2) 349-359. 10.1189/jlb.3A1214-580RR

2015

Pérez-Gómez E, Andradas C, Blasco-Benito S, Caffarel MM, García-Taboada E, Villa-Morales M, Moreno E, Hamann S, Martín-Villar E, Flores JM, Wenners A, Alkatout I, Klapper W, Röcken C, Bronsert P, Stickeler E, Staebler A, Bauer M, Arnold N, Soriano J, Pérez-Martínez M, Megías D, Moreno-Bueno G, Ortega-Gutiérrez S, Artola M, Vázquez-Villa H, Quintanilla M, Fernández-Piqueras J, Canela EI and McCormick PJ (2015). Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer. Journal of The National Cancer Institute  vol. 107, (6) 10.1093/jnci/djv077
Navarro G, Quiroz C, Moreno-Delgado D, Sierakowiak A, McDowell K, Moreno E, Rea W, Cai NS, Aguinaga D, Howell LA, Hausch F, Cortés A, Mallol J, Casadó V, Lluís C, Canela EI, Ferré S and McCormick PJ (2015). Orexin–corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine. Journal of Neuroscience  vol. 35, (17) 6639-6653. 10.1523/JNEUROSCI.4364-14.2015
Viñals X, Moreno E, Lanfumey L, Cordomí A, Pastor A, De La Torre R, Gasperini P, Navarro G, Howell LA, Pardo L, Lluís C, Canela EI, McCormick PJ, Maldonado R and Robledo P (2015). Cognitive impairment induced by delta9- tetrahydrocannabinol occurs through heteromers between cannabinoid CB1 and serotonin 5-HT2A receptors. Plos Biology  vol. 13, (7) 10.1371/journal.pbio.1002194
Marada S, Navarro G, Truong A, Stewart DP, Arensdorf AM, Nachtergaele S, Angelats E, Opferman JT, Rohatgi R, McCormick PJ and Ogden SK (2015). Functional Divergence in the Role of N-Linked Glycosylation in Smoothened Signaling. Plos Genetics  vol. 11, (8) 10.1371/journal.pgen.1005473

2014

Navarro G, Aguinaga D, Moreno E, Hradsky J, Reddy PP, Cortés A, Mallol J, Casadó V, Mikhaylova M, Kreutz MR, Lluís C, Canela EI, McCormick PJ and Ferré S (2014). Intracellular calcium levels determine differential modulation of allosteric interactions within G protein-coupled receptor heteromers. Chemistry and Biology  vol. 21, (11) 1546-1556. 10.1016/j.chembiol.2014.10.004
Guitart X, Navarro G, Moreno E, Yano H, Cai NS, Sánchez-Soto M, Kumar-Barodia S, Naidu YT, Mallol J, Cortés A, Lluís C, Canela EI, Casadó V, McCormick PJ and Ferré S (2014). Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: The dopamine D1-D3receptor heterotetramer. Molecular Pharmacology  vol. 86, (4) 417-429. 10.1124/mol.114.093096
Moreno E, Andradas C, Medrano M, Caffarel MM, Pérez-Gómez E, Blasco-Benito S, Gómez-Cañas M, Pazos MR, Irving AJ, Lluís C, Canela EI, Fernández-Ruiz J, Guzmán M, McCormick PJ and Sánchez C (2014). Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling. Journal of Biological Chemistry  vol. 289, (32) 21960-21972. 10.1074/jbc.M114.561761
Zhang Y, Calado R, Rao M, Hong JA, Meeker AK, Dumitriu B, Atay S, McCormick PJ, Garfield SH, Wangsa D, Padilla-Nash HM, Burkett S, Zhang M, Kunst TF, Peterson NR, Xi S, Inchauste S, Altorki NK, Casson AG, Beer DG, Harris CC, Ried T, Young NS and Schrump DS (2014). Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas. Plos One  vol. 9, (7) 10.1371/journal.pone.0101010
Bonaventura J, Rico AJ, Moreno E, Sierra S, Sánchez M, Luquin N, Farré D, Müller CE, Martínez-Pinilla E, Cortés A, Mallol J, Armentero MT, Pinna A, Canela EI, Lluís C, McCormick PJ, Lanciego JL, Casadó V and Franco R (2014). L-DOPA-treatment in primates disrupts the expression of A2A adenosine-CB1 cannabinoid-D2 dopamine receptor heteromers in the caudate nucleus. Neuropharmacology  vol. 79, 90-100. 10.1016/j.neuropharm.2013.10.036
Moreno E, Moreno-Delgado D, Navarro G, Hoffmann HM, Fuentes S, Rosell-Vilar S, Gasperini P, Rodríguez-Ruiz M, Medrano M, Mallol J, Cortés A, Casadó V, Lluís C, Ferré S, Ortiz J, Canela E and McCormick PJ (2014). Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects. Journal of Neuroscience  vol. 34, (10) 3545-3558. 10.1523/JNEUROSCI.4147-13.2014
Pinna A, Bonaventura J, Farré D, Sánchez M, Simola N, Mallol J, Lluís C, Costa G, Baqi Y, Müller CE, Cortés A, McCormick P, Canela EI, Martínez-Pinilla E, Lanciego JL, Casadó V, Armentero MT and Franco R (2014). L-DOPA disrupts adenosine A2A-cannabinoid CB1-dopamine D2 receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: Biochemical and behavioral studies. Experimental Neurology  vol. 253, 180-191. 10.1016/j.expneurol.2013.12.021

2013

Cristóvão-Ferreira S, Navarro G, Brugarolas M, Pérez-Capote K, Vaz SH, Fattorini G, Conti F, Lluis C, Ribeiro JA, McCormick PJ, Casadó V, Franco R and Sebastião AM (2013). A1R-A2AR heteromers coupled to Gs and Gi/0 proteins modulate GABA transport into astrocytes. Purinergic Signalling  vol. 9, (3) 433-449. 10.1007/s11302-013-9364-5
Gracia E, Moreno E, Cortés A, Lluís C, Mallol J, McCormick PJ, Canela EI and Casadó V (2013). Homodimerization of adenosine A1 receptors in brain cortex explains the biphasic effects of caffeine. Neuropharmacology  vol. 71, 56-69. 10.1016/j.neuropharm.2013.03.005
Navarro G, Moreno E, Bonaventura J, Brugarolas M, Farré D, Aguinaga D, Mallol J, Cortés A, Casadó V, Lluís C, Ferre S, Franco R, Canela E and McCormick PJ (2013). Cocaine Inhibits Dopamine D2 Receptor Signaling via Sigma-1-D2 Receptor Heteromers. Plos One  vol. 8, (4) 10.1371/journal.pone.0061245
Gracia E, Farré D, Cortés A, Ferrer-Costa C, Orozco M, Mallol J, Lluís C, Canela EI, McCormick PJ, Franco R, Fanelli F and Casadó V (2013). The catalytic site structural gate of adenosine deaminase allosterically modulates ligand binding to adenosine receptors. Faseb Journal  vol. 27, (3) 1048-1061. 10.1096/fj.12-212621
Franco R, Martínez-Pinilla E, Ricobaraza A and McCormick PJ (2013). Challenges in the development of heteromer-GPCR-based drugs. Progress in Molecular Biology and Translational Science  10.1016/B978-0-12-386931-9.00006-4
Navarro G, McCormick PJ, Mallol J, Lluís C, Franco R, Cortés A, Casadó V, Canela EI and Ferré S (2013). Detection of receptor heteromers involving dopamine receptors by the sequential BRET-FRET technology. Methods in Molecular Biology  vol. 964, 95-105. 10.1007/978-1-62703-251-3_7

2012

Casanova V, Naval-Macabuhay I, Massanella M, Rodríguez-García M, Blanco J, Gatell JM, García F, Gallart T, Lluis C, Mallol J, Franco R, Climent N and McCormick PJ (2012). Adenosine Deaminase Enhances the Immunogenicity of Human Dendritic Cells from Healthy and HIV-Infected Individuals. Plos One  vol. 7, (12) 10.1371/journal.pone.0051287
Luquin N, Sierra S, Rico AJ, Gómez-Bautista V, Roda E, Conte-Perales L, Franco R, McCormick P, Labandeira-García JL and Lanciego JL (2012). Unmasking adenosine 2A receptors (A2ARs) in monkey basal ganglia output neurons using cholera toxin subunit B (CTB). Neurobiology of Disease  vol. 47, (3) 347-357. 10.1016/j.nbd.2012.05.006
Callén L, Moreno E, Barroso-Chinea P, Moreno-Delgado D, Cortés A, Mallol J, Casadó V, Lanciego JL, Franco R, Lluis C, Canela EI and McCormick PJ (2012). Cannabinoid receptors CB 1 and CB 2 form functional heteromers in brain. Journal of Biological Chemistry  vol. 287, (25) 20851-20865. 10.1074/jbc.M111.335273
González S, Rangel-Barajas C, Peper M, Lorenzo R, Moreno E, Ciruela F, Borycz J, Ortiz J, Lluís C, Franco R, McCormick PJ, Volkow ND, Rubinstein M, Floran B and Ferré S (2012). Dopamine D 4 receptor, but not the ADHD-associated D 4.7 variant, forms functional heteromers with the dopamine D 2S receptor in the brain. Molecular Psychiatry  vol. 17, (6) 650-662. 10.1038/mp.2011.93
Navarro G, Hradsky J, Lluís C, Casadó V, McCormick PJ, Kreutz MR and Mikhaylova M (2012). NCS-1 associates with adenosine A 2A receptors and modulates receptor function. Frontiers in Molecular Neuroscience  (APRIL) 10.3389/fnmol.2012.00053
Gasperini P, Espigol-Frigole G, McCormick PJ, Salvucci O, Maric D, Uldrick TS, Polizzotto MN, Yarchoan R and Tosato G (2012). Kaposi sarcoma herpesvirus promotes endothelial-to-mesenchymal transition through notch-dependent signaling. Cancer Research  vol. 72, (5) 1157-1169. 10.1158/0008-5472.CAN-11-3067
González S, Moreno-Delgado D, Moreno E, Pérez-Capote K, Franco R, Mallol J, Cortés A, Casadó V, Lluís C, Ortiz J, Ferré S, Canela E and McCormick PJ (2012). Circadian-related heteromerization of adrenergic and dopamine d4 receptors modulates melatonin synthesis and release in the pineal gland. Plos Biology  vol. 10, (6) 10.1371/journal.pbio.1001347

2011

Cristóvão-Ferreira S, Navarro G, Brugarolas M, Pérez-Capote K, Vaz SH, Fattorini G, Conti F, Lluis C, Ribeiro JA, McCormick PJ, Casadó V, Franco R and Sebastião AM (2011). Modulation of GABA transport by adenosine A 1R-A 2AR heteromers, which are coupled to both G s- and G i/o-Proteins. Journal of Neuroscience  vol. 31, (44) 15629-15639. 10.1523/JNEUROSCI.2526-11.2011
Hradsky J, Raghuram V, Reddy PP, Navarro G, Hupe M, Casado V, McCormick PJ, Sharma Y, Kreutz MR and Mikhaylova M (2011). Post-translational membrane insertion of tail-anchored transmembrane EF-hand Ca 2+ sensor calneurons requires the TRC40/Asna1 protein chaperone. Journal of Biological Chemistry  vol. 286, (42) 36762-36776. 10.1074/jbc.M111.280339
Moreno E, Vaz SH, Cai NS, Ferrada C, Quiroz C, Barodia SK, Kabbani N, Canela EI, McCormick PJ, Lluis C, Franco R, Ribeiro JA, Sebastião AM and Ferré S (2011). Dopamine-galanin receptor heteromers modulate cholinergic neurotransmission in the rat ventral hippocampus. Journal of Neuroscience  vol. 31, (20) 7412-7423. 10.1523/JNEUROSCI.0191-11.2011
Vendrell M, Molero A, González S, Pérez-Capote K, Lluis C, McCormick PJ, Franco R, Cortés A, Casadó V, Albericio F and Royo M (2011). Biotin ergopeptide probes for dopamine receptors. Journal of Medicinal Chemistry  vol. 54, (4) 1080-1090. 10.1021/jm101566d
Moreno E, Hoffmann H, Gonzalez-Sepúlveda M, Navarro G, Casadó V, Cortés A, Mallol J, Vignes M, McCormick PJ, Canela EI, Lluís C, Moratalla R, Ferré S, Ortiz J and Franco R (2011). Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway. Journal of Biological Chemistry  vol. 286, (7) 5846-5854. 10.1074/jbc.M110.161489

2010

Navarro G, Moreno E, Aymerich M, Marcellino D, McCormick PJ, Mallol J, Cortésa A, Casadó V, Canela EI, Ortiz J, Fuxe K, Lluís C, Ferré S and Franco R (2010). Direct involvement of σ-1 receptors in the dopamine D1 receptor-mediated effects of cocaine. Proceedings of The National Academy of Sciences of The United States of America  vol. 107, (43) 18676-18681. 10.1073/pnas.1008911107
De La Luz Sierra M, Sakakibara S, Gasperini P, Salvucci O, Jiang K, McCormick PJ, Segarra M, Stone J, Maric D, Zhu J, Qian X, Lowy DR and Tosato G (2010). The transcription factor Gfi1 regulates G-CSF signaling and neutrophil development through the Ras activator RasGRP1. Blood  vol. 115, (19) 3970-3979. 10.1182/blood-2009-10-246967

2009

McCormick PJ, Segarra M, Gasperini P, Gulino AV and Tosato G (2009). Impaired recruitment of GrK6 and β-arrestin2 causes delayed internalization and desensitization of a WHIM syndrome-associated CXCR4 mutant receptor. Plos One  vol. 4, (12) 10.1371/journal.pone.0008102

2008

McCormick PJ, Dumaresq-Doiron K, Pluviose AS, Pichette V, Tosato G and Lefrancois S (2008). Palmitoylation controls recycling in lysosomal sorting and trafficking. Traffic  vol. 9, (11) 1984-1997. 10.1111/j.1600-0854.2008.00814.x
Segarra M, Williams CK, De La Luz Sierra M, Bernardo M, McCormick PJ, Maric D, Regino C, Choyke P and Tosato G (2008). DII4 activation of Notch signaling reduces tumor vascularity and inhibits tumor growth. Blood  vol. 112, (5) 1904-1911. 10.1182/blood-2007-11-126045
Barral DC, Cavallari M, McCormick PJ, Garg S, Magee AI, Bonifacino JS, De Libero G and Brenner MB (2008). CD1a and MHC class I follow a similar endocytic recycling pathway. Traffic  vol. 9, (9) 1446-1457. 10.1111/j.1600-0854.2008.00781.x

2007

Sierra MDLL, Gasperini P, McCormick PJ, Zhu J and Tosato G (2007). Transcription factor Gfi-1 induced by G-CSF is a negative regulator of CXCR4 in myeloid cells. Blood  vol. 110, (7) 2276-2285. 10.1182/blood-2007-03-081448
Lefrançois S and McCormick PJ (2007). The Arf GEF GBF1 is required for GGA recruitment to Golgi membranes. Traffic  vol. 8, (10) 1440-1451. 10.1111/j.1600-0854.2007.00623.x
Saurí A, McCormick PJ, Johnson AE and Mingarro I (2007). Sec61α and TRAM are Sequentially Adjacent to a Nascent Viral Membrane Protein during its ER Integration. Journal of Molecular Biology  vol. 366, (2) 366-374. 10.1016/j.jmb.2006.11.052

2006

Salvucci O, Sierra MDLL, Martina JA, McCormick PJ and Tosato G (2006). EphB2 and EphB4 receptors forward signaling promotes SDF-1-induced endothelial cell chemotaxis and branching remodeling. Blood  vol. 108, (9) 2914-2922. 10.1182/blood-2006-05-023341

2005

McCormick PJ, Martina JA and Bonifacino JS (2005). Involvement of clathrin and AP-2 in the trafficking of MHC class II molecules to antigen-processing compartments. Proceedings of The National Academy of Sciences of The United States of America  vol. 102, (22) 7910-7915. 10.1073/pnas.0502206102

2004

Woolhead CA, McCormick PJ and Johnson AE (2004). Nascent membrane and secretory proteins differ in FRET-detected folding far inside the ribosome and in their exposure to ribosomal proteins. Cell  vol. 116, (5) 725-736. 10.1016/S0092-8674(04)00169-2

2003

McCormick PJ, Miao Y, Shao Y, Lin J and Johnson AE (2003). Cotranslational protein integration into the ER membrane is mediated by the binding of nascent chains to translocon proteins. Molecular Cell  vol. 12, (2) 329-341. 10.1016/S1097-2765(03)00304-6