Dr Eleni Hagi-Pavli

Eleni Hagi-Pavli

Senior Lecturer

Dental Institute, Centre for Oral Immunobiology and Regenerative
Faculty of Medicine and Dentistry, Queen Mary University of London


Publications of specific relevance to Predictive in vitro Models


Koidou VP, Hagi‐Pavli E, Nibali L and Donos N (2023). Elucidating the molecular healing of intrabony defects following non‐surgical periodontal therapy: A pilot study. Wiley  Journal of Periodontal Research  vol. 59, (1) 53-62. 10.1111/jre.13207
Alhallak K, Hagi-Pavli E and Nankali A (2023). A review on clinical use of CAD/CAM and 3D printed dentures. Springer Nature  British Dental Journal  1-5. 10.1038/s41415-022-5401-5


Karen-Ng LP, Ahmad US, Gomes L, Hunter KD, Wan H, Hagi-Pavli E and Parkinson EK (2022). Extracellular Prostaglandins E1 and E2 and Inflammatory Cytokines Are Regulated by the Senescence Program in Potentially Premalignant Oral Keratinocytes. Mdpi  Cancers  vol. 14, (11) 10.3390/cancers14112636
Nibali L, Stephen A, Hagi-Pavli E, Allaker R, Pino AD, Terranova V, Pisano M, Marca SD, Ferrara V, Scicali R, Giordano M, Purrello F, Donos N and Malatino L (2022). Analysis of gingival crevicular fluid biomarkers in patients with metabolic syndrome. Elsevier  Journal of Dentistry  vol. 118, 10.1016/j.jdent.2022.104065


Novak T, Hamedi M, Bergmeier LA, Fortune F and Hagi-Pavli E (2021). Saliva and Serum Cytokine Profiles During Oral Ulceration in Behçet’s Disease., Editors: Czerkinsky C. Frontier  Frontiers in Immunology  vol. 12, (22) 724900-724920. 10.3389/fimmu.2021.724900
Koidou VP, Hagi‐Pavli E, Cross S, Nibali L and Donos N (2021). Molecular profiling of intrabony defects' gingival crevicular fluid. Wiley  Journal of Periodontal Research  vol. 57, (1) 152-161. 10.1111/jre.12948


Koidou VP, Cavalli N, Hagi-Pavli E, Nibali L and Donos N (2020). Expression of inflammatory biomarkers and growth factors in gingival crevicular fluid at different healing intervals following non-surgical periodontal treatment: A systematic review. Wiley  Journal of Periodontal Research  10.1111/jre.12795
Novak T, Fortune F, Bergmeier L, Khan I and Hagi-Pavli E (2020). Neutrophil elastase and endogenous inhibitors in Behçet’s disease saliva. Wiley  Clinical and Experimental Immunology  10.1111/cei.13483


Seoudi N, Bergmeier LA, Hagi-Pavli E, Bibby D and Fortune F (2015). The seroprevalence and salivary shedding of herpesviruses in Behçet's syndrome and recurrent aphthous stomatitis. Taylor & Francis  Journal of Oral Microbiology  vol. 7, (1) 10.3402/jom.v7.27156


Hagi-Pavli E, Williams DM, Rowland JL, Thornhill M and Cruchley AT (2014). Characterizing the immunological effects of oral healthcare ingredients using an in vitro reconstructed human epithelial model. Food Chem Toxicol  vol. 74, 139-148. 10.1016/j.fct.2014.09.007
Hamedi M, Bergmeier LA, Hagi-Pavli E, VARTOUKIAN SR and Fortune F (2014). Differential expression of Suppressor of Cytokine Signalling proteins in Behçet’s Disease. Wiley Online  Scandinavian Journal of Immunology  vol. 80, (5) 369-376. 10.1111/sji.12211
Seoudi N, Bergmeier LA, Hagi-Pavli E, Bibby D, Curtis MA and Fortune F (2014). The role of TLR2 and 4 in Behçet's disease pathogenesis. Innate Immun  vol. 20, (4) 412-422. 10.1177/1753425913498042
Bergmeier LA, Hamedi M, Hagi-Pavli E, Seoudi N, Senusi A, Ijaz H and Fortune F (2014). HSP27 as a diagnostic marker in the saliva of Behcet's disease.


WHILEY RA, Sheikh NP, Mushtaq N, Hagi-Pavli E, Personne Y, Javaid D and Waite RD (2013). Differential Potentiation of Virulence of the Pseudomonas aeruginosa Cystic Fibrosis. Oxford Journals  Epidemics: The Journal of Infectious Diseases  vol. 209, (5) 769-780. 10.1093/infdis/jit568
Adegun OK, Tomlins PH, Hagi-Pavli E, Bader DL and Fortune F (2013). Quantitative optical coherence tomography of fluid-filled oral mucosal lesions. Lasers Med Sci  vol. 28, (5) 1249-1255. 10.1007/s10103-012-1208-y


Adegun OK, Tomlins PH, Hagi-Pavli E, McKenzie G, Piper K, Bader DL and Fortune F (2012). Quantitative analysis of optical coherence tomography and histopathology images of normal and dysplastic oral mucosal tissues. Lasers Med Sci  vol. 27, (4) 795-804. 10.1007/s10103-011-0975-1
Whiley RA, Cruchley AT, Gore C and Hagi-Pavli E (2012). Candida albicans strain-dependent modulation of pro-inflammatory cytokine release by in vitro oral and vaginal mucosal models. Cytokine  vol. 57, (1) 89-97. 10.1016/j.cyto.2011.10.017


Macey M, Hagi-Pavli E, Stewart J, Wallace GR, Stanford M, Shirlaw P and Fortune F (2011). Age, gender and disease-related platelet and neutrophil activation ex vivo in whole blood samples from patients with Behçet's disease. Rheumatology (Oxford)  vol. 50, (10) 1849-1859. 10.1093/rheumatology/ker177


Tomlins PH, Adegun O, Hagi-Pavli E, Piper K, Bader D and Fortune F (2010). Scattering attenuation microscopy of oral epithelial dysplasia. Spie  Journal of Biomedical Optics  vol. 15, (6) 10.1117/1.3505019
Bergmeier LA, Adegun O, Seoudi N, Hamedi M, Hagi-Pavli E and Fortune F (2010). INDUCIBLE HUMAN HEAT SHOCK PROTEIN (HSP70) IS ELEVATED IN THE SALIVA OF BEHCET'S PATIENTS. Clin Exp Rheumatol  vol. 28, (4) S123-S123.
Seoudi N, Hagi-Pavli E, Bergmeier L, Stewart J, Curtis M and Fortune F (2010). THE ORAL HEALTH AND MICROBIOTA OF UK BEHCET'S DISEASE PATIENTS. Clin Exp Rheumatol  vol. 28, (4) S124-S124.
Hagi-Pavli E, Macey M, Stewart J, Wallace G, Stanford M, Shirlaw P and Fortune F (2010). AGE, GENDER AND DISEASE RELATED PLATELET AND NEUTROPHIL ACTIVATION IN BEHCET'S. Clin Exp Rheumatol  vol. 28, (4) S128-S128. 10.1093/rheumatology/ker177
Hagi-Pavli E, Bergmeier L, Khan I, Seoudi N and Fortune F (2010). SECRETORY LEUKOCYTE PROTEASE INHIBITOR (SLPI) IN BEHCET'S PATIENTS SALIVA. Clin Exp Rheumatol  vol. 28, (4) S128-S128.
Hagi-Pavli E, Novak T, Bergmeier L, Seoudi N, Moeinian M and Fortune F (2010). PLASMA AND SALIVA CYTOKINE PROFILES IN BEHCET'S DISEASE: DO CYTOKINE LEVELS IN PLASMA CORRELATE WITH LEVELS IN SALIVA? Clin Exp Rheumatol  vol. 28, (4) S129-S129.


Mumcu G, Niazi S, Stewart J, Hagi-Pavli E, Gokani B, Seoudi N, Ergun T, Yavuz S, Stanford M, Fortune F and Direskeneli H (2009). Oral health and related quality of life status in patients from UK and Turkey: a comparative study in Behcet's disease. J Oral Pathol Med  vol. 38, (5) 406-409. 10.1111/j.1600-0714.2009.00752.x


Teh MT, Tilakaratne WM, Chaplin T, Young BD, Ariyawardana A, Pitiyage G, Lalli A, Stewart JE, Hagi-Pavli E, Cruchley A, Waseem A and Fortune F (2008). Fingerprinting genomic instability in oral submucous fibrosis. J Oral Pathol Med  vol. 37, (7) 430-436. 10.1111/j.1600-0714.2008.00643.x
Stewart JE, Mumcu G, Haque A, Hagi-Pavli E, Freysdot J, Direskeneli H, Shirlaw P, Wallace G, Stanford MR and Fortune F (2008). DIFFERENTIAL CYTOKINE EXPRESSION BY PBMC'S OF BEHCET'S PATIENTS: INFLUENCE OF SERUM AND SALIVA. Clin Exp Rheumatol  vol. 26, (4) S9-S9.
Tilakaratne WM, Iqbal Z, Teh MT, Ariyawardana A, Pitiyage G, Cruchley A, Stewart JE, Hagi-Pavli E, Lalli A, Waseem A, Parkinson EK and Fortune F (2008). Upregulation of HIF-1 alpha in malignant transformation of oral submucous fibrosis. J Oral Pathol Med  vol. 37, (6) 372-377. 10.1111/j.1600-0714.2007.00625.x
Mumcu G, Stewart J, Hagi-Pavli E, Gokani B, Seoudi N, Ergun T, Yavuz S, Stanford MR, Direskeneli H and Fortune F (2008). ORAL HEALTH AND QUALITY OF LIFE STATUS IN PATIENTS FROM UK AND TURKEY: A COMPARATIVE STUDY IN BEHCET'S DISEASE. Clin Exp Rheumatol  vol. 26, (4) S5-S6. 10.1111/j.1600-0714.2009.00752.x
Hagi-Pavli E, Plequezuelos O, Seoudi N, Stewart JE, Shirlaw P, Wallace G, Stanford MR and Fortune F (2008). EXPRESSION OF EPIDERMAL GROWTH FACTOR RECEPTOR AND ITS LIGANDS IN THE ORAL CAVITY OF BEHCET'S DISEASE PATIENTS. Clin Exp Rheumatol  vol. 26, (4) S9-S10.
Lalli A, Tilakaratne WM, Ariyawardana A, Fitchett C, Leigh IM, Hagi-Pavli E, Cruchley AT, Parkinson EK, Teh MT, Fortune F and Waseem A (2008). An altered keratinocyte phenotype in oral submucous fibrosis: correlation of keratin K17 expression with disease severity. J Oral Pathol Med  vol. 37, (4) 211-220. 10.1111/j.1600-0714.2007.00609.x


Tilakaratne W, Iqbal Z, Teh MT, Ariyawardana A, Pitiyage G, Cruchley A, Hagi-Pavli E, Lalli A, Waseem A, Parkinson K and Fortune F (2007). P245 Up regulation of HIF-1a in the progression and malignant transformation of oral submucous fibrosis. Elsevier  Oral Oncology Supplement  vol. 2, (1) 204-205. 10.1016/s1744-7895(07)70522-9


Tosanguan J, Hagi-Pavli E, Kapas S and Cruchley AT (2005). The role NF-kappa Bin mercury-induced IL-8 production by oral keratinocytes. Immunology  vol. 116, 28-29.
Hagi-Pavli E, Farthing PM, Henshaw FN and Kapas S (2005). Presentation of ICAM-1 protein at the cell surface of oral keratinocytes in the presence of adrenomedullin and corticotrophin. Cell Physiol Biochem  vol. 15, (1-4) 167-174. 10.1159/000083649


Pleguezuelos O, Hagi-Pavli E, Crowther G and Kapas S (2004). Adrenomedullin signals through NF-kappaB in epithelial cells. Febs Lett  vol. 577, (1-2) 249-254. 10.1016/j.febslet.2004.10.019
Kapas S, Pahal K, Cruchley AT, Hagi-Pavli E and Hinson JP (2004). Expression of adrenomedullin and its receptors in human salivary tissue. J Dent Res  vol. 83, (4) 333-337. 10.1177/154405910408300412
Hagi-Pavli E, Farthing PM and Kapas S (2004). Stimulation of adhesion molecule expression in human endothelial cells (HUVEC) by adrenomedullin and corticotrophin. Am J Physiol Cell Physiol  vol. 286, (2) C239-C246. 10.1152/ajpcell.00036.2003


Lundqvist CK, Hagi-Pavli E, Kapas S, Williams DM, Thornhill MH and Cruchley A (2003). HgCl2 induction of oral keratimacyte IL-8 production is mediated by the MAP kinase pathway. J Dent Res  vol. 82, B95-B95.


Kapas S, Bansal A, Bhargava V, Maher R, Malli D, Hagi-Pavli E and Allaker RP (2001). Adrenomedullin expression in pathogen-challenged oral epithelial cells. Peptides  vol. 22, (9) 1485-1489. 10.1016/S0196-9781(01\)00470-3
CRUCHLEY AT, Leigh IM, Navsaria H, Williams DM, Hagi-Pavli EP, Wertz PW, Selvaratnam L and Squier CA (2001). Permeability barrier properties of oral keratinocyte cultures: a model of intact human oral mucosa. Oral Diseases  vol. 7, (4) 252-258. 10.1034/j.1601-0825.2001.70409.x


Ellone MM, Cruchley AT, Hagi-Pavli E, Patel M, Braden M and Williams DM (2000). PERMEABILITY OF ORAL MUCOSAL TISSUES TO DEXAMETHASONE. Portland Press  Biochemical Society Transactions  vol. 28, (5) a201-a201. 10.1042/bst028a201a


Hagi‐Pavli EP, Simms CS, Ostler EL, Brocklehurst K and Gallacher G (1999). ChemInform Abstract: Synthesis of a Transition State Analogue for the Hydrolysis of Cocaine: Assistance to Phosphonylation of a 3β‐Hydroxytropane by a Neighboring Amide Group. Wiley  Cheminform  vol. 30, (43) no-no. 10.1002/chin.199943209
Hagi-Pavli EP, Simms CS, Ostler EL, Brocklehurst K and Gallacher G (1999). Synthesis of a transition state analogue for the hydrolysis of cocaine: Assistance to phosphonylation of a 3β-hydroxytropane by a neighbouring amide group. Elsevier  Bioorganic & Medicinal Chemistry Letters  vol. 9, (13) 1881-1884. 10.1016/s0960-894x(99)00293-0


Kapas S, Hagi‐Pavli E, Brown DW, Chhajlani V and Farthing PM (1998). Direct effects of corticotrophin on oral keratinocyte cell proliferation. Wiley  The Febs Journal  vol. 256, (1) 75-79. 10.1046/j.1432-1327.1998.2560075.x
Taichman NS, Cruchley AT, Fletcher LM, Hagi-Pavli EP, Paleolog EM, Abrams WR, Booth V, Edwards RM and Malamud D (1998). Vascular endothelial growth factor in normal human salivary glands and saliva: a possible role in the maintenance of mucosal homeostasis. Laboratory Investigation  vol. 78, (7) 869-875.


Kapas S, Brown DW, Farthing PM and Hagi-Pavli E (1997). Adrenomedullin has mitogenic effects on human oral keratinocytes: involvement of cyclic AMP. Wiley  Febs Letters  vol. 418, (3) 287-290. 10.1016/s0014-5793(97)01384-7
Hinson JP, Hagi-Pavli E, Thomson LM and Kapas S (1997). PROADRENOMEDULLIN N-TERMINAL 20-PEPTIDE (PAMP) RECEPTORS AND SIGNAL TRANSDUCTION IN THE RAT ADRENAL GLAND. Elsevier  Life Sciences  vol. 62, (5) 439-443. 10.1016/s0024-3205(97)01137-5
Kapas S, Thomson L, Hagi-Pavli E and Hinson JP (1997). Pro-adrenomedullfn 20 peptide (pamp) binds to specific-receptors in the rat adrenal gland. Faseb Journal  vol. 11, (9)
RESMINI M, VIGNA R, SIMMS C, BARBER NJ, HAGI-PAVLI EP, WATTS AB, VERMA C, GALLACHER G and BROCKLEHURST K (1997). Characterization of the hydrolytic activity of a polyclonal catalytic antibody preparation by pH-dependence and chemical modification studies: evidence for the involvement of Tyr and Arg side chains as hydrogen-bond donors. Portland Press  Biochemical Journal  vol. 326, (1) 279-287. 10.1042/bj3260279