Scientists at the CPM in Queen Mary University of London have developed advanced 3D printed human skin models that mimic key immune responses in real human tissue, opening the door to more accurate studies of skin diseases and inflammatory processes.

Developed by researchers at the Blizard Institute, the novel models include blood vessel-like microfluidic channels that can deliver circulating immune cells into the system, allowing scientists to study how the immune system reacts to threats such as bacteria without needing to rely on animal models.

The paper was published in Advanced Science. The studies were carried out by Dr Sarah Hindle as part of her PhD, along with Holly Bachas Brook and Dr Alexander Chrysanthou in Prof. John Connelly's group. The work also involved collaboration with Dr Matthew Caley in the Centre for Cell Biology and Cutaneous Research and Dr Emma Chambers in the Immunobiology group.

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